File size: 119,955 Bytes
8903732
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
1001
1002
1003
1004
1005
1006
1007
1008
1009
1010
1011
1012
1013
1014
1015
1016
1017
1018
1019
1020
1021
1022
1023
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
1034
1035
1036
1037
1038
1039
1040
1041
1042
1043
1044
1045
1046
1047
1048
1049
1050
1051
1052
1053
1054
1055
1056
1057
1058
1059
1060
1061
1062
1063
1064
1065
1066
1067
1068
1069
1070
1071
1072
1073
1074
1075
1076
1077
1078
1079
1080
1081
1082
1083
1084
1085
1086
1087
1088
1089
1090
1091
1092
1093
1094
1095
1096
1097
1098
1099
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112
1113
1114
1115
1116
1117
1118
1119
1120
1121
1122
1123
1124
1125
1126
1127
1128
1129
1130
{"id": "000001", "text": "Is treatment of class II malocclusion recommended during childhood?"}
{"id": "000002", "text": "Which are the main relative contraindications for surgery first orthognathic approach?"}
{"id": "000006", "text": "What is the recommended orientation for the placement of the IMF screw?"}
{"id": "000007", "text": "Which are the advantages of endoscopic approach to treat massive arterial epistaxis?"}
{"id": "000009", "text": "Does maxillary segmentation osteotomy produce neurosensory disturbances?"}
{"id": "000010", "text": "Which locations of IMF screws are associated to harming tooth roots?"}
{"id": "000013", "text": "What is the predictability of upper molar distalization with clear aligners?"}
{"id": "000014", "text": "Which are the main inconveniences of MAD treatment for patients suffering OSAS?"}
{"id": "000015", "text": "What are the benefits of using a self-etching primer for braces?"}
{"id": "000016", "text": "How do they test the strength of the adhesive used on braces?"}
{"id": "000017", "text": "What is the relationship between fixed orthodontic appliances and the development of white spot lesions?"}
{"id": "000018", "text": "Which are the best locations for IMF screw placement?"}
{"id": "000019", "text": "Which are the disadvantages of surgery first orthognathic approach?"}
{"id": "000020", "text": "What should be considered when using AI for medical information?"}
{"id": "000021", "text": "What is the usual cause of auditory or hearing issues after orthognathic surgery?"}
{"id": "000023", "text": "Which are the main methods used to treat massive head and neck epistaxis?"}
{"id": "000024", "text": "What are the limitations of using clear aligners?"}
{"id": "000028", "text": "Which are the main vertical compensations of the maxillomandibular placement for prediction of final occlusion?"}
{"id": "000029", "text": "Which are the disadvantages of 3D printed splints in orthognathic surgery?"}
{"id": "000032", "text": "What intervention is suggested in case of simple malocclusions?"}
{"id": "000035", "text": "What is the prevalence of alveolar nerve injury after an orthognathic surgery?"}
{"id": "000036", "text": "Why is it not recommended to put the IMF screws as far as possible from the tooth roots?"}
{"id": "000038", "text": "Are there any contraindications for the use of IMF screws?"}
{"id": "000039", "text": "What is used to bleach teeth?"}
{"id": "000041", "text": "Which are the main risk factors for inferior alveolar nerve injury during orthognathic surgery?"}
{"id": "000043", "text": "Which are the main factors associated with an increased length of orthodontic-orthognathic treatment?"}
{"id": "000044", "text": "Is there any benefit to using fluoride after bleaching?"}
{"id": "000045", "text": "Is the self-etching primer adhesive strong enough for braces?"}
{"id": "000049", "text": "Can clear aligner treatment be used for all types of tooth movement?"}
{"id": "000050", "text": "What are the potential consequences of not preventing white spot lesions during orthodontic treatment?"}
{"id": "000053", "text": "What are the recommendations for wire cerclage placement when longstanding postoperative MMF is expected?"}
{"id": "000055", "text": "What are the main challenges in achieving accurate tooth movement with clear aligners?"}
{"id": "000056", "text": "Are teeth in line of osteotomy of any risk during sagittal split osteotomy of the mandible?"}
{"id": "000057", "text": "What is the most frequent complication after an orthognathic surgery procedure?"}
{"id": "000059", "text": "Can clear aligners really produce more stable results compared to fixed appliances?"}
{"id": "000060", "text": "What is the recommended protocol for MAD treatment in patients with obstructive sleep apnea syndrome?"}
{"id": "000061", "text": "Is clear aligner suitable to treat extrusion?"}
{"id": "000062", "text": "What are the elements that affect the bond strength of orthodontic adhesives?"}
{"id": "000065", "text": "What are the advantages of CAD/CAM for surgical planning of orthognathic surgery?"}
{"id": "000068", "text": "What is the most frequent type of dental injury when anterior and buccal teeth are associated with facial fractures?"}
{"id": "000070", "text": "Which are the aims of presurgical preparation in the conventional orthognathic surgery presurgical protocol?"}
{"id": "000072", "text": "Can clear aligners really achieve root parallelism and torque?"}
{"id": "000073", "text": "How long does it usually take to undergo orthodontic treatment in adulthood?"}
{"id": "000075", "text": "How does clear aligner treatment compare to traditional braces?"}
{"id": "000076", "text": "What is obstructive sleep apnea (OSAS)?"}
{"id": "000077", "text": "How do fixed orthodontic appliances contribute to the development of white spot lesions?"}
{"id": "000079", "text": "What is the purpose of studies on tooth enamel roughness?"}
{"id": "000081", "text": "What is a self-etching primer used for in dentistry?"}
{"id": "000082", "text": "Which are the main transverse compensations of the maxillomandibular placement for prediction of final occlusion?"}
{"id": "000083", "text": "What methodology is used to evaluate the adhesive remnant on teeth?"}
{"id": "000085", "text": "Do clear aligners work on older adults?"}
{"id": "000086", "text": "What testing methods are used to assess the effectiveness of different adhesives?"}
{"id": "000087", "text": "Why is it important to evaluate the oral hygiene status of patients during orthodontic treatment?"}
{"id": "000088", "text": "What are the main complications related to surgical hardware in orthognathic surgery?"}
{"id": "000089", "text": "What is the prognosis of recovery of nerve injury after an orthognathic surgery procedure?"}
{"id": "000092", "text": "What are the main factors that drive the association between facial and dentoalveolar injuries?"}
{"id": "000093", "text": "Is 3D computer assisted surgical simulation system enough for the surgical planning?"}
{"id": "000095", "text": "How to diagnose OSAS?"}
{"id": "000096", "text": "What movements are clear aligners least effective in controlling?"}
{"id": "000097", "text": "What are the clinical advantages of using an unfilled adhesive system?"}
{"id": "000100", "text": "Do experimental adhesives leave a lot of glue on teeth after removing braces?"}
{"id": "000101", "text": "Which are the main anteroposterior compensations of the maxillomandibular placement for prediction of final occlusion?"}
{"id": "000102", "text": "What is the prevalence of white spot lesions in patients undergoing orthodontic treatment?"}
{"id": "000103", "text": "What is the most frequent mechanism of injury in facial fractures associated with dental injuries?"}
{"id": "000104", "text": "What auxiliary methods improve the effectiveness of clear aligners?"}
{"id": "000105", "text": "How does the filled adhesive system compare in terms of adhesive remnants after debonding?"}
{"id": "000106", "text": "How does the predictability of clear aligners compare with traditional braces?"}
{"id": "000107", "text": "Which patients have more risk of OSAS?"}
{"id": "000109", "text": "How accurate is clear aligner treatment for rotating teeth?"}
{"id": "000110", "text": "What are the usual functional problems caused by inferior alveolar nerve injury after an orthognathic surgery?"}
{"id": "000111", "text": "What are the differences between demyelinating and axonal nerve injury in terms of recovery?"}
{"id": "000113", "text": "What are the criteria that should be acknowledged for screw placement?"}
{"id": "000117", "text": "Which are the advantages of 3D systems in surgical planning for orthognathic surgery?"}
{"id": "000118", "text": "Are there non-surgical treatments for OSAS?"}
{"id": "000119", "text": "What are the advantages of personalized splints in orthognathic surgery?"}
{"id": "000120", "text": "Can tooth bleaching damage the enamel?"}
{"id": "000122", "text": "What is the role of oral hygiene in preventing white spot lesions during orthodontic treatment?"}
{"id": "000123", "text": "What are the main methods for testing sensory nerve function?"}
{"id": "000124", "text": "What is the most common location of a fracture in facial trauma associated with dental injuries?"}
{"id": "000125", "text": "What are the findings regarding the roughness of enamel after various treatments?"}
{"id": "000126", "text": "Which are the main risks of suffering OSAS?"}
{"id": "000131", "text": "How does the shear bond strength of the new unfilled SEP compare to traditional adhesives?"}
{"id": "000133", "text": "What are the main problems concerning bad splits in orthogntaic surgery?"}
{"id": "000135", "text": "How does hydrogen peroxide affect tooth color?"}
{"id": "000136", "text": "Why do teeth look whiter after bleaching?"}
{"id": "000138", "text": "Which are the most frequently affected teeth associated with facial fractures?"}
{"id": "000140", "text": "What future improvements are suggested for AI models like ChatGPT in healthcare?"}
{"id": "000142", "text": "Does the application of fluoride after bleaching have any observable effects on enamel?"}
{"id": "000143", "text": "What are the potential effects of tooth bleaching on enamel?"}
{"id": "000144", "text": "How common are white spot lesions in patients undergoing orthodontic treatment?"}
{"id": "000146", "text": "What are the benefits of using ChatGPT in healthcare?"}
{"id": "000147", "text": "Which are the advantages of 3D computer-assisted surgical simulation systems in orthognathic surgery?"}
{"id": "000148", "text": "How effective are clear aligners in straightening teeth?"}
{"id": "000149", "text": "What is the age most frequently associated with facial trauma?"}
{"id": "000153", "text": "What is done after bleaching to refine the teeth's surface?"}
{"id": "000154", "text": "How is the presurgial preparation of patients undergoing surgery first orthognathic approach?"}
{"id": "000155", "text": "What are the best materials for IMF screws to avoid screw shaft fractures or shearing of the screw head?"}
{"id": "000157", "text": "Which are the main factors associated to suffering a bad split in orthognathic surgery?"}
{"id": "000158", "text": "Is clear aligner treatment suitable for all ages?"}
{"id": "000159", "text": "Does tooth bleaching really work?"}
{"id": "000160", "text": "Why are Psuedoaneurysm dangerous?"}
{"id": "000163", "text": "Which are the main disadvantages of orthodontic interventions before and after orthognathic surgery?"}
{"id": "000164", "text": "Which are the factors that should be taken in consideration when deciding the location of IMF screws placement?"}
{"id": "000165", "text": "Is orthognathic surgery harmful for the temporomandibular joint?"}
{"id": "000166", "text": "What are the physiological stages of sleep?"}
{"id": "000167", "text": "What are the symptoms of white spot lesions?"}
{"id": "000168", "text": "What is the purpose of using fluoride after bleaching?"}
{"id": "000170", "text": "Can white spot lesions be treated?"}
{"id": "000171", "text": "What are white spot lesions and why do they form during orthodontic treatment?"}
{"id": "000176", "text": "Which are the required orthodontic criteria for surgery first approach applications?"}
{"id": "000177", "text": "What is usual cause of hemorrhage after maxillary osteotomy in orthognathic surgery?"}
{"id": "000178", "text": "Why is it important to prevent white spot lesions during orthodontic treatment?"}
{"id": "000181", "text": "What is the recommended indication of treatment for severe OSAS?"}
{"id": "000183", "text": "Why are surgical splints necessary for orthognathic surgery?"}
{"id": "000185", "text": "What is a bad split in orthognathic surgery?"}
{"id": "000187", "text": "How to avoid condylar sag during orthognathic surgery?"}
{"id": "000188", "text": "Which is the disadvantage of using an archwire bonded directly to tooth surfaces before orthognathic surgery in SFOA?"}
{"id": "000190", "text": "What are the typical temporomandibular joint symptoms that can appear in a patient undergoing maxillomandibular advancement?"}
{"id": "000193", "text": "Are clear aligners effective in moving teeth roots?"}
{"id": "000196", "text": "What is the classification of severity of OSAS?"}
{"id": "000198", "text": "What post-treatment steps are recommended after tooth bleaching?"}
{"id": "000199", "text": "Is there any maneuver that can help reduce the rate of bad splits in sagittal split osteotomy of the mandible during orthognathic surgery?"}
{"id": "000200", "text": "What is the usual management of a delayed epistaxis after orthognathic surgery?"}
{"id": "000201", "text": "What dose and frequency of Dupilumab can be used to treat acquired perforating dermatosis?"}
{"id": "000202", "text": "What are the histologic findings of primary cutaneous amyloidosis?"}
{"id": "000203", "text": "How quickly can I expect to see improvements in my skin condition with upadacitinib?"}
{"id": "000204", "text": "How does upadacitinib compare to other treatments for atopic dermatitis in terms of speed of response?"}
{"id": "000207", "text": "What are the healthcare resource utilization patterns for patients with hidradenitis suppurativa?"}
{"id": "000208", "text": "What are common cardiac manifestations of Fabry disease?"}
{"id": "000210", "text": "What is amyloid?"}
{"id": "000215", "text": "What is amyloidosis?"}
{"id": "000219", "text": "What are triggers for Darier Disease?"}
{"id": "000221", "text": "What kind of treatments are available for hidradenitis suppurativa?"}
{"id": "000222", "text": "What is the presentation of Hyper IgE Syndrome?"}
{"id": "000227", "text": "Can IL-17 inhibitors be used to treat Netherton syndrome?"}
{"id": "000231", "text": "What genes are mutated in familial amyloidosis?"}
{"id": "000234", "text": "Is amyloidosis a genetic disease?"}
{"id": "000236", "text": "What is Hidradenitis Suppurativa?"}
{"id": "000237", "text": "What biologics can be used to treat Netheron Syndrome?"}
{"id": "000239", "text": "What is the mode of inheritance of Hyper IgE Syndrome?"}
{"id": "000243", "text": "Can signs of harlequin ichthyosis be seen or evaluated prenatally?"}
{"id": "000245", "text": "Is upadacitinib as effective in adults as it is in younger patients?"}
{"id": "000248", "text": "What stain is most used to diagnose amyloidosis in biopsies?"}
{"id": "000250", "text": "What are the renal manifestations of Fabry Disease?"}
{"id": "000253", "text": "What can you see on prenatal ultrasound of babies with Harlequin ichthyosis?"}
{"id": "000261", "text": "What is primary cutaneous amyloidosis?"}
{"id": "000266", "text": "What are the clinical features of angiokeratomas in Fabry Disease?"}
{"id": "000269", "text": "What are subtypes of cutaneous amyloidosis?"}
{"id": "000270", "text": "What is the presentation of lichen amyloidosis?"}
{"id": "000273", "text": "What is Fabry disease?"}
{"id": "000274", "text": "What is the pathogenesis of amyloidosis?"}
{"id": "000276", "text": "What are the types of amyloidosis affecting the skin?"}
{"id": "000277", "text": "What medical conditions are associated with perforating dermatoses?"}
{"id": "000278", "text": "What are the implications of upadacitinib treatment on daily activities and patients' well-being?"}
{"id": "000283", "text": "What are the long-term benefits of using upadacitinib for atopic dermatitis?"}
{"id": "000288", "text": "What causes Fabry disease?"}
{"id": "000290", "text": "Does nodular amyloidosis have systemic involvement?"}
{"id": "000293", "text": "What special stains can be used for cutaneous amyloidosis?"}
{"id": "000297", "text": "Is surgery a common treatment for hidradenitis suppurativa?"}
{"id": "000298", "text": "What is the most common form of cutaneous amyloidosis?"}
{"id": "000299", "text": "Can upadacitinib help with the sleep problems caused by atopic dermatitis?"}
{"id": "000300", "text": "What is the pathogenesis of Darier Disease?"}
{"id": "000304", "text": "What other condition has similar presentation and histology as Darier Disease?"}
{"id": "000305", "text": "What gene causes Harlequin ichthyosis?"}
{"id": "000306", "text": "Does upadacitinib improve mental health for patients with atopic dermatitis?"}
{"id": "000307", "text": "What is the impact of hidradenitis suppurativa on patients' well-being?"}
{"id": "000308", "text": "What are the effects of Fabry Disease on the kidneys?"}
{"id": "000311", "text": "What are the current treatment options for Hidradenitis Suppurativa?"}
{"id": "000313", "text": "What organ systems are most affected in Fabry Disease?"}
{"id": "000319", "text": "What is the main treatment for Harlequin ichthyosis?"}
{"id": "000320", "text": "What are some early signs of Fabry Disease?"}
{"id": "000325", "text": "What are some dermatological issues that would prompt suspicion for  Fabry Disease?"}
{"id": "000327", "text": "What interleukins are important in the pathogenesis of pruritus?"}
{"id": "000332", "text": "What is the mode of inheritance of multiple endocrine neoplasia 2A?"}
{"id": "000335", "text": "What is the structure of amyloid protein?"}
{"id": "000338", "text": "How does upadacitinib impact the well-being of patients with moderate-to-severe atopic dermatitis?"}
{"id": "000340", "text": "What lab monitoring should be done in neonatal patients on oral retinoids and at what frequency?"}
{"id": "000341", "text": "What is the typical skin finding in Fabry Disease?"}
{"id": "000343", "text": "When is the typical onset of Fabry Disease?"}
{"id": "000347", "text": "What is the prevalence of Hidradenitis Suppurativa?"}
{"id": "000348", "text": "How does Fabry Disease present?"}
{"id": "000352", "text": "What is the most frequent presentation of acquired perforating dermatosis?"}
{"id": "000354", "text": "What gene mutations cause epidermolysis bullosa?"}
{"id": "000359", "text": "What are clinical manifestations of Fabry Disease?"}
{"id": "000363", "text": "What patient-reported outcomes are used in the upadacitinib studies?"}
{"id": "000376", "text": "How common is hidradenitis suppurativa?"}
{"id": "000378", "text": "What dose of oral retinoids should be given to babies with harlequin ichthyosis?"}
{"id": "000383", "text": "How should people use upadacitinib?"}
{"id": "000385", "text": "What are treatments for angiokeratomas?"}
{"id": "000386", "text": "What exacerbates Darier Disease?"}
{"id": "000388", "text": "What is the mode of inheritance of Fabry Disease?"}
{"id": "000391", "text": "What are the key mediators of itch?"}
{"id": "000395", "text": "What is the role of biologics in the treatment of hidradenitis suppurativa?"}
{"id": "000397", "text": "What is the cause of Porokeratosis?"}
{"id": "000400", "text": "What are the indications for surgical treatment of Hidradenitis Suppurativa?"}
{"id": "000401", "text": "What are the effects of microbiota on intestinal health?"}
{"id": "000404", "text": "What are the key findings in the analysis of intestinal microbiota in colitis?"}
{"id": "000405", "text": "What is the Barcelona Clinic Liver Cancer staging system?"}
{"id": "000406", "text": "What are the clinical implications of the relationship between NAFLD and sleep apnea?"}
{"id": "000410", "text": "Describe the pathogenesis of diseases caused by altered microbiota."}
{"id": "000411", "text": "What are the possible treatments after liver cancer recurs?"}
{"id": "000414", "text": "What immune mediated pathways are involved in the development of fibrosis in PSC?"}
{"id": "000415", "text": "What are the benefits of improving gut microbiota?"}
{"id": "000417", "text": "Can the gut microbiome influence colorectal anastomotic leak?"}
{"id": "000419", "text": "How is recurrence detected in hepatocellular carcinoma patients after surgery?"}
{"id": "000420", "text": "What mechanisms does Salvia miltiorrhiza use to combat obesity?"}
{"id": "000421", "text": "What does 'overall survival' mean?"}
{"id": "000424", "text": "Can certain gram-negative cocci in the gut microbiota be exploited to prevent excessive fat accumulation in hepatocytes?"}
{"id": "000425", "text": "How can we achieve more effective gene therapy for gastrointestinal tumours?"}
{"id": "000427", "text": "In patients who are at a higher risk of post-operative infection, which technique to treat HCCA would be recommended?"}
{"id": "000428", "text": "How can gut microbiota alterations contribute to PSC progression?"}
{"id": "000430", "text": "What is the benefit of combination therapy with anti-TNF and immunomodulators in the treatment of moderate to severe Crohn's disease?"}
{"id": "000431", "text": "How effective is liver resection?"}
{"id": "000432", "text": "How does the intestinal microbiota interfere with an individual's behavior?"}
{"id": "000433", "text": "What is non-alcoholic fatty liver disease?"}
{"id": "000435", "text": "How can we influence intestinal flora to optimize the immune system?"}
{"id": "000437", "text": "What is Salvia miltiorrhiza and what does it do?"}
{"id": "000438", "text": "Is it common to find cancer during celiac disease diagnosis?"}
{"id": "000440", "text": "How does Salvia miltiorrhiza influence lipid metabolism in obese rats?"}
{"id": "000443", "text": "How does the connection between the gut and the liver influence primary sclerosing cholangitis?"}
{"id": "000444", "text": "Why is radiotherapy less effective in treating certain tumour pathologies?"}
{"id": "000448", "text": "What is the relationship between primary sclerosing cholangitis and inflammatory bowel disease?"}
{"id": "000450", "text": "Is immunotherapy more relevant as a treatment for esophageal cancers than other drug therapies?"}
{"id": "000451", "text": "What are the risks of non-alcoholic fatty liver disease?"}
{"id": "000454", "text": "How do microbiota affect the intestinal mucus barrier?"}
{"id": "000459", "text": "What surgical intervention has been shown to reduce complications related to portal hypertension?"}
{"id": "000463", "text": "What job do intestinal microbiota and metabolites play in ulcerative colitis?"}
{"id": "000464", "text": "What specific changes in gut microbiota are induced by Salvia miltiorrhiza in the context of a high-fat diet?"}
{"id": "000467", "text": "If a patient has portal hypertension are they automatically at risk of GI bleeds?"}
{"id": "000468", "text": "What are the specific characteristics of peptic ulcer disease in children?"}
{"id": "000469", "text": "What are the long-term survival rates for patients undergoing liver resection for hepatocellular carcinoma?"}
{"id": "000470", "text": "What does 'curative resection' mean?"}
{"id": "000471", "text": "What dietary recommendations are suggested for patients with NAFLD and sleep apnea?"}
{"id": "000472", "text": "How does the intestinal flora influence the development of primary sclerosing cholangitis?"}
{"id": "000474", "text": "Does intraoperative assessment of anastomotic perfusion using ICG-FA reduce the risk of postoperative colorectal anastomotic leak?"}
{"id": "000475", "text": "When should a colorectal anastomotic leak be suspected?"}
{"id": "000476", "text": "Can changes in microbiota lead to ulcerative colitis?"}
{"id": "000478", "text": "In the event of a discrepancy between radiological criteria suggestive of hepatocarcinoma and biological and viral criteria, what differential diagnoses should be considered?"}
{"id": "000479", "text": "Does the response to treatment differ between Crohn's patients who have been previously treated with biologics, versus the ones who are starting them for the first time?"}
{"id": "000480", "text": "Is the low-FODMAP diet interesting as a remission treatment for Crohn's disease?"}
{"id": "000481", "text": "What are the main types of sleep apnea syndrome?"}
{"id": "000483", "text": "What is the most likely cause of increased gastrointestinal bleeding in patients with portal hypertension?"}
{"id": "000484", "text": "What does it mean when they say Salvia miltiorrhiza has anti-obesity effects?"}
{"id": "000485", "text": "What are the current challenges in treating primary sclerosing cholangitis?"}
{"id": "000487", "text": "What methods are used to diagnose non-alcoholic fatty liver disease?"}
{"id": "000488", "text": "Does longer operative time increase morbidity in colorectal surgery?"}
{"id": "000489", "text": "Is there a case for developing other therapies to better control gastroesophageal acid reflux?"}
{"id": "000490", "text": "Is the training and learning curve relevant in colorectal surgery?"}
{"id": "000493", "text": "How can we intervene in the diet of patients suffering from inflammatory bowel disease to achieve good symptom control without adversely affecting their quality of life?"}
{"id": "000494", "text": "Are there any predictive factors or specific biomarkers that could help identify patients most likely to benefit from immunotherapy for esophageal squamous cell carcinoma?"}
{"id": "000495", "text": "Should C-Reactive Protein (CRP) be measured during the postoperative period of colorectal surgery?"}
{"id": "000497", "text": "Does Salvia miltiorrhiza extract work to reduce body fat?"}
{"id": "000498", "text": "How do microbiota and metabolites interact with the immune system?"}
{"id": "000500", "text": "What is the influence of metabolic bariatric surgery on patients with both obesity and sleep apnea?"}
{"id": "000501", "text": "What role does the gut play in primary sclerosing cholangitis?"}
{"id": "000502", "text": "Can fat distribution cause more complications?"}
{"id": "000504", "text": "What molecular biology techniques could be applied to limit the progression of digestive tract tumors?"}
{"id": "000505", "text": "What methodologies are used to study the role of microbiota in ulcerative colitis?"}
{"id": "000508", "text": "Can Salvia miltiorrhiza help with losing fat?"}
{"id": "000511", "text": "What changes occur in the body due to a high-fat diet?"}
{"id": "000512", "text": "Which between TNF inhibitors and ustekinumab are more beneficial in the long-term treatment of Crohn's disease?"}
{"id": "000513", "text": "What is the relationship between non-alcoholic fatty liver disease and sleep apnea?"}
{"id": "000519", "text": "What are the symptoms of ulcerative colitis?"}
{"id": "000520", "text": "What findings can develop as a consequence of portal hypertension?"}
{"id": "000522", "text": "Does dextran sulfate sodium induce colitis?"}
{"id": "000523", "text": "What is used to diagnose celiac disease?"}
{"id": "000527", "text": "By what mechanism does a splenectomy help in the management of portal hypertension?"}
{"id": "000528", "text": "Would a prehabilitation protocol focused on improving the nutritional status reduce the rate of anastomotic leaks in patients undergoing colorectal surgery?"}
{"id": "000529", "text": "What other conditions can be found during an endoscopy for celiac disease?"}
{"id": "000532", "text": "Are there any specific proteins that can be exploited for more targeted treatment of digestive tumours?"}
{"id": "000533", "text": "Is gender a risk factor for colorectal anastomotic leak?"}
{"id": "000534", "text": "Can genetic susceptibility influence primary sclerosing cholangitis?"}
{"id": "000536", "text": "Can changing the gut bacteria help treat primary sclerosing cholangitis?"}
{"id": "000537", "text": "What is the role of exercise in managing non-alcoholic fatty liver disease?"}
{"id": "000538", "text": "What is the significance of microvascular invasion in hepatocellular carcinoma?"}
{"id": "000539", "text": "What role does intestinal flora play in the pathogenesis of primary sclerosing cholangitis (PSC)?"}
{"id": "000540", "text": "Can children be diagnosed with celiac disease without a biopsy?"}
{"id": "000543", "text": "Are there any metabolic degradation products that could be exploited for more precise monitoring of patients with hepatic steatosis?"}
{"id": "000545", "text": "Is pre-treatment to reduce tumour size more beneficial associated with surgery in advanced esophageal tumours?"}
{"id": "000546", "text": "How does Salvia miltiorrhiza contribute to the overall health of patients with obesity?"}
{"id": "000547", "text": "How to decide of a hepatocellular carcinoma patient needs liver resection?"}
{"id": "000549", "text": "What are the common gut microbiota alterations observed in patients with primary sclerosing cholangitis?"}
{"id": "000551", "text": "How does Salvia miltiorrhiza affect the gut?"}
{"id": "000552", "text": "If you suspect an anastomotic leak, what test should you do?"}
{"id": "000553", "text": "What factors influence the choice between different types of liver resection?"}
{"id": "000554", "text": "How could immune cell surface proteins be harnessed for more effective treatment of esophageal squamous cell carcinomas?"}
{"id": "000555", "text": "Is TAF15 involved in pathologies other than gastrointestinal tumors?"}
{"id": "000557", "text": "What types of bacteria found in overgrowth in the gastrointestinal tract are associated with development of hepatic sequelae?"}
{"id": "000561", "text": "What are the potential benefits of CPAP therapy for patients with sleep apnea?"}
{"id": "000562", "text": "How does the intestinal barrier function?"}
{"id": "000563", "text": "How does the leaky gut hypothesis explain the role of intestinal dysbiosis in the development of primary sclerosing cholangitis"}
{"id": "000564", "text": "Could a colorectal anastomotic leak be ruled out after the first week?"}
{"id": "000565", "text": "Do different surgical approaches have the same rate of colorectal anastomotic leak?"}
{"id": "000566", "text": "How is non-alcoholic fatty liver disease diagnosed?"}
{"id": "000569", "text": "What is the role of bile acids in primary sclerosing cholangitis?"}
{"id": "000570", "text": "How do certain microorganisms in the intestinal flora influence the development of fatty liver?"}
{"id": "000571", "text": "Is there any difference between the types of diverting stoma preferred after colorectal surgery?"}
{"id": "000572", "text": "What is continuous positive airway pressure therapy?"}
{"id": "000574", "text": "What surgical procedure can reduce mortality in PSC?"}
{"id": "000575", "text": "What is the role of intraoperative ultrasound in liver surgery?"}
{"id": "000577", "text": "Are there other diseases linked with non-alcoholic fatty liver disease?"}
{"id": "000578", "text": "Is celiac disease genetic?"}
{"id": "000580", "text": "Is there a need for an alternative to exclusive enteral nutrition for the treatment of inflammatory bowel disease?"}
{"id": "000582", "text": "Which biologics would be a suitable treatment for Crohn’s disease patients who are unresponsive to anti-TNF?"}
{"id": "000583", "text": "Is there any comorbidity index used in abdominal surgery?"}
{"id": "000584", "text": "What are the broader implications of Salvia miltiorrhiza's effects on lipid metabolism?"}
{"id": "000586", "text": "How can diet help manage non-alcoholic fatty liver disease?"}
{"id": "000587", "text": "Whenever possible, is it preferable to perform elective surgery to avoid anastomotic leaks?"}
{"id": "000588", "text": "What is fecal microbiota transplantation?"}
{"id": "000590", "text": "What composition of the microbiota can be used as a biomarker?"}
{"id": "000591", "text": "What is the relation between sleep apnea and the liver?"}
{"id": "000594", "text": "Can surgical experience impact the incidence of colorectal anastomotic leak?"}
{"id": "000595", "text": "Could an intervention at the level of the intestinal microbial flora be relevant to reduce the prevalence of hepatic steatosis?"}
{"id": "000596", "text": "What role do microbiota play in therapeutic efficacy?"}
{"id": "000597", "text": "What causes ulcerative colitis?"}
{"id": "000600", "text": "Which investigative methods are recommended as first-line treatment for occult GI bleeding?"}
{"id": "000605", "text": "How can we assess a group of people's knowledge of genetics?"}
{"id": "000606", "text": "What is the advantage of using Mendelian randomization?"}
{"id": "000608", "text": "Is there a link between the different types of epigenetic modifications?"}
{"id": "000609", "text": "How can nucleotide sequence changes responsible for muscular dystrophy not detected by multiplex PCR be detected?"}
{"id": "000610", "text": "What are circRNAs?"}
{"id": "000616", "text": "Can methylRAD be used when in samples with low DNA concentration, such as in exosome samples?"}
{"id": "000617", "text": "When processing DNA methylation data (from Epigenome-wide association studies), the CpG-sites that are SNPs can be affecting the results?"}
{"id": "000618", "text": "How many heritable factors are known to be related with drug response in stroke?"}
{"id": "000619", "text": "Are genetic factors influencing leprosy?"}
{"id": "000621", "text": "Can a vegetarian diet in a pregnant woman have consequences on the health of the fetus?"}
{"id": "000623", "text": "How can integrating genotyping data with proteomic massive data enhance our understanding of a pathology?"}
{"id": "000625", "text": "How are lncRNAs identified?"}
{"id": "000626", "text": "What are the findings about the genetic structure of Rana hanluica?"}
{"id": "000627", "text": "Are there specific genomic sites for markers of chronic kidney disease?"}
{"id": "000628", "text": "What are the implications of using genetic material in the search for new metabolites that are risk factors for diseases such as cardiovascular pathologies?"}
{"id": "000630", "text": "To identify a haplogroup of an ethnic origin, which marker should be targeted?"}
{"id": "000632", "text": "Which kind of cell to cell connections are mainly affected in BBB disruption?"}
{"id": "000633", "text": "What are mitochondrial diseases?"}
{"id": "000634", "text": "What are the chances of having alpha-mannosidosis?"}
{"id": "000636", "text": "Which conservation implications are suggested for Rana hanluica?"}
{"id": "000637", "text": "Is dna methylation always associated with gene expression changes of the gene where the dna methylation is located?"}
{"id": "000638", "text": "How are lncRNAs and circRNAs identified in a genome-wide study?"}
{"id": "000639", "text": "What genetic markers are used to study Rana hanluica?"}
{"id": "000640", "text": "Is it possible to take into account the co-variety of different DNA methylation-sites?"}
{"id": "000641", "text": "What is the significance of piRNAs in regards with the immune system?"}
{"id": "000643", "text": "What tools are used to analyze RNA data?"}
{"id": "000644", "text": "How do variations in keratinocyte regulatory elements near the genes SOX9 and KLF5 interact in the pathogenesis of HS?"}
{"id": "000645", "text": "Which is the most common epigenetic modification in mammals?"}
{"id": "000646", "text": "Can external factors modify the DNA methylation?"}
{"id": "000648", "text": "Can drinking alcohol affect kidney stones?"}
{"id": "000649", "text": "What is the immune response to Mycobacterium leprae?"}
{"id": "000656", "text": "Which biomolecular pathways can be modified by the alleles involved in the genesis of a varicose vein?"}
{"id": "000657", "text": "Is there any epigenetic modification associated with treatment response in stroke?"}
{"id": "000658", "text": "Are there any constraints on transferring polygenic scores to another ethnic group?"}
{"id": "000659", "text": "Are changes in DNA methylation associated with the risk of myocardial infarction?"}
{"id": "000660", "text": "How do mitochondrial diseases typically progress?"}
{"id": "000661", "text": "How valid is microsatellite genotyping for haplogrouping?"}
{"id": "000662", "text": "Can DNA methylation be studied in the entire genome using bisulfite conversion treatments?"}
{"id": "000663", "text": "What is the genetic variability of the Tunisian Barbarine sheep?"}
{"id": "000664", "text": "Which genes are associated with craniofacial morphology?"}
{"id": "000666", "text": "What are common complications of a school-age child with Rett syndrome?"}
{"id": "000667", "text": "Is epigenetics linked with changes in the gene expression?"}
{"id": "000668", "text": "Can mitochondrial diseases be inherited?"}
{"id": "000670", "text": "How are non-coding RNAs involved in the pathophysiology of multiple sclerosis?"}
{"id": "000672", "text": "What could be the constraint on the use of metabolites produced by genetic data as a biomarker of a specific pathology?"}
{"id": "000673", "text": "How do I determine whether a genetic variant that is altering a particular protein in the blood is also modifying the gene expression in other tissues"}
{"id": "000675", "text": "Are there any new recommendations for discovering geographic and ethnic patterns based on DNA?"}
{"id": "000677", "text": "Are the enzymes involved in DNA methylation maintenance the same also involved in \"the novo\" DNA methylation?"}
{"id": "000678", "text": "How are genetic traits associated to specific physical characteristics?"}
{"id": "000679", "text": "What methods can be used to assess genetic diversity?"}
{"id": "000680", "text": "What challenges are associated with studying rare genetic disorders?"}
{"id": "000681", "text": "Which are the expected genes to be affected in HS if we undergo a study that looks for SNPs?"}
{"id": "000682", "text": "Can the ancestry of subjects be estimated from DNA methylation studies?"}
{"id": "000683", "text": "Is DNA methylation in brain microvesicles altered after stroke?"}
{"id": "000684", "text": "What are the current findings about the relationship between alcohol consumption and kidney stones?"}
{"id": "000685", "text": "Is DNA methylation important in processes involving blood brain barrier reparation after stroke?"}
{"id": "000687", "text": "What genetic studies have been done on the Tunisian Barbarine sheep?"}
{"id": "000692", "text": "What is the role of KLF5 gene in the proposed pathogenesis of HS?"}
{"id": "000694", "text": "When we identify a genetic risk factor in stroke, how can we determine whether this factor is a cause or a consequence of stroke?"}
{"id": "000695", "text": "Is hydroximethylation a common epigenomic mechanism in the genome?"}
{"id": "000696", "text": "What is the intra-ethnic and inter-ethnic genetic diversity in terms of Y-DNA haplogroups among populations on the Indian subcontinent?"}
{"id": "000698", "text": "Can different environmental conditions alter the DNA methylation?"}
{"id": "000699", "text": "What are common complications of a teenager with Rett syndrome"}
{"id": "000700", "text": "Does the frequency of drinking alcohol matter for kidney stones?"}
{"id": "000702", "text": "Is the effect of epigenetics in regulating genetic levels dependent on the methylation site?"}
{"id": "000703", "text": "Can the integration of genetics and proteomics allow us to find treatments for diseases such as multiple sclerosis?"}
{"id": "000705", "text": "How is leprosy diagnosed?"}
{"id": "000706", "text": "Why is the integration of different omics in genetic studies important?"}
{"id": "000708", "text": "What are the consequences of leprosy?"}
{"id": "000709", "text": "How can we do a translational study to link genes to a disease and at the same time study the metabolic pathways involved without using animal models?"}
{"id": "000710", "text": "From which tissues, whose extraction is non-invasive, can DNA methylation information be obtained?"}
{"id": "000711", "text": "If I am planning an epigenetic study, and I have to choose an epigenetic mechanism to be studied, which is most usually selected in published studies?"}
{"id": "000712", "text": "What is the cause of leprosy?"}
{"id": "000713", "text": "Can pQTL studies help us to prioritize genes in genomic studies?"}
{"id": "000714", "text": "What could be the therapeutic value of long non-coding RNA assays in multiple sclerosis?"}
{"id": "000715", "text": "Why are wild potatoes more resistant to certain diseases than cultivated ones?"}
{"id": "000717", "text": "Can the expression of a gene be affected by DNA methylation?"}
{"id": "000718", "text": "Is it important to evolve towards personalized medicine in the case of stroke?"}
{"id": "000719", "text": "How is leprosy classified?"}
{"id": "000721", "text": "What methods were used to study the genome of the Tunisian Barbarine sheep?"}
{"id": "000722", "text": "What kinds of errors can taint the causal links resulting from the use of genetic data?"}
{"id": "000723", "text": "What are non-coding RNAs?"}
{"id": "000725", "text": "How reliable is the Y chromosome marker?"}
{"id": "000726", "text": "Why does the genetic pattern of nephropathy differ according to an individual's ethnic origin?"}
{"id": "000728", "text": "What are the effects of migration on genetics?"}
{"id": "000729", "text": "Why is genetic research important for the Tunisian Barbarine sheep?"}
{"id": "000730", "text": "In candidate genes, the results have an increase probability to be false positive or false negative?"}
{"id": "000732", "text": "What facial phenotypes are associated with a genetic anomaly?"}
{"id": "000733", "text": "How does the genetic structure of a breed influence its conservation strategies?"}
{"id": "000735", "text": "Are there genes uniquely associated with large vessel stroke?"}
{"id": "000736", "text": "What is the role of circRNAs in relation with miRNAs?"}
{"id": "000740", "text": "What is the role of SOX9 gene in the proposed pathogenesis of HS?"}
{"id": "000742", "text": "Is the BBB disrupture associated with worse stroke outcome?"}
{"id": "000743", "text": "What is the role of cirnRNAs?"}
{"id": "000744", "text": "Can EM-seq be used to study DNA methylation in different species?"}
{"id": "000746", "text": "How does alcohol consumption frequency influence the risk of developing upper urinary calculi?"}
{"id": "000749", "text": "do the consequences of DNA methylation depend on its location?"}
{"id": "000750", "text": "How can the integration of genetic and proteomic data help us in gene prioritization?"}
{"id": "000751", "text": "How do lncRNAs interact with miRNAs to regulate gene expression?"}
{"id": "000752", "text": "How does genetic diversity impact the conservation of local livestock breeds?"}
{"id": "000753", "text": "What role do population-specific studies play in understanding genetic disorders like alpha-mannosidosis?"}
{"id": "000755", "text": "What is unknown in the study of long non-coding RNAs?"}
{"id": "000756", "text": "What is the CCncRNAdb database for research?"}
{"id": "000757", "text": "What are the difficulties in annotating lncRNA sequences?"}
{"id": "000758", "text": "How can genetic studies impact the protection and the sustainable management of specific species?"}
{"id": "000760", "text": "What are the implications of studying the genetic diversity of local livestock breeds?"}
{"id": "000762", "text": "Which methods allow detection of a higher amount of DNA methylation, those based on restriction enzymes or bisulfite conversion?"}
{"id": "000765", "text": "What methods can be used to calculate the number of alpha-mannosidosis carriers?"}
{"id": "000766", "text": "What is the role of lncRNAs?"}
{"id": "000768", "text": "Are lncRNAs bad?"}
{"id": "000770", "text": "Are kidney stones linked to other diseases?"}
{"id": "000771", "text": "Is it possible to identify false positives in candidate gene studies?"}
{"id": "000772", "text": "Is the BBB important in determining cerebral ischemia prognosis?"}
{"id": "000774", "text": "Is it possible to analyze DNA methylation in regions with low DNA density?"}
{"id": "000775", "text": "What are the different types of non-coding RNAs?"}
{"id": "000776", "text": "Can changing my drinking habits reduce my risk of kidney stones?"}
{"id": "000781", "text": "Why is Rana hanluica important for research?"}
{"id": "000782", "text": "What are the applications of proteogenomics in disease research?"}
{"id": "000784", "text": "What are the main genes that can modify the likelihood of varicose veins?"}
{"id": "000786", "text": "What is the Tunisian barbarine sheep known for?"}
{"id": "000788", "text": "What are the implications of crossbreeding on the genetic diversity of local breeds?"}
{"id": "000789", "text": "Can non-coding RNA testing be a biomarker of the clinical course and severity of multiple sclerosis?"}
{"id": "000790", "text": "What are the limits of the gene-environment interaction method in assessing a group of people's knowledge of genetics?"}
{"id": "000792", "text": "What are the main applications of pQTLs?"}
{"id": "000793", "text": "Is the blood brain barrier disrupted in ischemic processes?"}
{"id": "000794", "text": "What is the function of Matrix Metalloproteinases (MMPs) in a stroke?"}
{"id": "000795", "text": "Is the age an important factor in determining stroke outcomes?"}
{"id": "000796", "text": "The Olink guide suggests using linear regression to analyze protein data, but the NPX values do not follow a normal distribution. What strategies can I use to address this issue?"}
{"id": "000797", "text": "Are the enzymatic methods used to detect DNA methylation able to detect methylation per single-bases?"}
{"id": "000798", "text": "How effective is whole-genome sequencing in diagnosing hereditary muscle diseases?"}
{"id": "000800", "text": "What is the impact of kidney stones on quality of life?"}
{"id": "000802", "text": "Does the hemorrhage duration due to brain artery rupture after endovascular\ntreatment have any impact in the neurological outcome?"}
{"id": "000803", "text": "Can plasma exosomes derived from different cells be used as predictors of disease risk?"}
{"id": "000804", "text": "How does mindfulness affect the brain in PTSD patients?"}
{"id": "000806", "text": "Does serum saline overload improve collateral status and reduce lesion size in a patient with acute cerebral infarct?"}
{"id": "000808", "text": "What is the anatomical organization of glymphatic system?"}
{"id": "000810", "text": "Can mindfulness help with emotional regulation in PTSD?"}
{"id": "000811", "text": "What are the main features seen in the brain of someone with Alzheimer's?"}
{"id": "000813", "text": "What does emotional conflict indicate in terms of psychiatric symptoms?"}
{"id": "000814", "text": "What neurobiological changes are associated with mindfulness-based treatments in PTSD?"}
{"id": "000815", "text": "Can systematised analysis of CT and MRI scans of stroke patients help to predict their outcome when they are in the emergency department?"}
{"id": "000816", "text": "Can RIC treatment be used to obtain multi-tissue protection after stroke?"}
{"id": "000818", "text": "Can hemicraniectomy as neurosurgical procedure improve outcome after malignant stroke?"}
{"id": "000819", "text": "How does adolescence impact vulnerability to psychiatric conditions?"}
{"id": "000820", "text": "Why do some people find it hard to make decisions?"}
{"id": "000821", "text": "How is ischemic stroke cured?"}
{"id": "000823", "text": "Is there any antidote for factor IIa inhibitors associated bleedings?"}
{"id": "000824", "text": "For what molecular reasons is the hypertensive response associated with worse prognosis in patients with\nprognosis of patients with cerebral hematoma?"}
{"id": "000828", "text": "How long does it typically take for hemorrhagic transformation to occur after a stroke?"}
{"id": "000830", "text": "Can RIC be used as an ischemic stroke treatment?"}
{"id": "000832", "text": "What is Alzheimer's disease?"}
{"id": "000833", "text": "What are the neuropathological features of Alzheimer's disease?"}
{"id": "000835", "text": "Why are genomic studies useful for finding potential therapeutic targets for the long-term progression of stroke?"}
{"id": "000838", "text": "Why do some people develop schizophrenia?"}
{"id": "000839", "text": "Are there currently any treatments to improve the long-term outcome of suffering a stroke\""}
{"id": "000840", "text": "What resources are required to perform a N-of-1 trial for psychosis?"}
{"id": "000843", "text": "What factors contribute to individual susceptibility to psychopathology?"}
{"id": "000844", "text": "What are the symptoms of PTSD?"}
{"id": "000845", "text": "Is it possible to have different gene expression depending on the presence of specific miRNA?"}
{"id": "000850", "text": "Can changes in the brain make someone more likely to develop psychiatric disorders?"}
{"id": "000851", "text": "Why is my patient with restless legs syndrome deteriorating despite treatment with pramiprexole?"}
{"id": "000852", "text": "Are exosomes a common cell communication mechanism shared between different cell types?"}
{"id": "000853", "text": "What role do environmental factors play in the development of Alzheimer's disease?"}
{"id": "000854", "text": "Which alzheimer's disease risk factors are associated with impaired glymphatic system?"}
{"id": "000855", "text": "If we can predict the occurrence of hemorrhagic transformation and control its progression, can we improve the prognosis for a stroke patient?"}
{"id": "000856", "text": "What is the flow direction of the cerebro-spinal fluid?"}
{"id": "000858", "text": "Is always the return of normal blood flow after stroke associated with a good prognosis?"}
{"id": "000859", "text": "To isolate exosomes, is it required to use complex technology and to have advanced lab knowledge?"}
{"id": "000860", "text": "Are doctors today able to anticipate which patients will suffer a haemorrhagic transformation after a stroke?"}
{"id": "000861", "text": "What are the challenges of using exposure therapy for PTSD?"}
{"id": "000862", "text": "Can the stroke outcome be predicted by the pattern of miRNA contained in neuronal-derived exosomes?"}
{"id": "000863", "text": "Is there a relation between choice-making and anxiety?"}
{"id": "000865", "text": "How does extracellular protein accumulation clear in the central nervous system?"}
{"id": "000866", "text": "Which molecules are associated with progressive improvement of blood pressure control after cerebral hemorrhage?\nfollowing cerebral hemorrhage?"}
{"id": "000869", "text": "Which neurosurgical procedure improves outcome of patients with hemorrhagic Stroke?"}
{"id": "000870", "text": "How does mindfulness-based cognitive therapy work?"}
{"id": "000871", "text": "Can Alzheimer's disease be inherited?"}
{"id": "000872", "text": "What clinical data can help determine if a patient is at higher or lower risk for hemorrhagic transformation?"}
{"id": "000873", "text": "Which are the clinical and radiological predictors of malignant stroke?"}
{"id": "000875", "text": "What is the role of AQP4 in the CSF flow?"}
{"id": "000876", "text": "What is the implication of astrocytes in the development of trigeminal neuralgia?"}
{"id": "000877", "text": "What is the prognosis for patients who experience hemorrhagic transformation as a complication after a stroke?"}
{"id": "000878", "text": "What sensitivity tests are utilized in Mendelian randomization (MR) analyses?"}
{"id": "000879", "text": "Is MCI a diagnosis hallmark in AD?"}
{"id": "000881", "text": "What specific brain regions are affected by DCC haploinsufficiency?"}
{"id": "000882", "text": "How can artificial intelligence assist in improving clinical practice in stroke field?"}
{"id": "000883", "text": "What are the radiological features associated with an increased risk of malignant stroke?"}
{"id": "000884", "text": "What does 'plasticity' in the dopamine system mean?"}
{"id": "000885", "text": "Is there experimental evidence of the role of astrocytes in the trigeminal nucleus caudalus?"}
{"id": "000886", "text": "What is the histologic architecture of the paravascular space of the glymphatic system?"}
{"id": "000887", "text": "What causes Alzheimer's disease?"}
{"id": "000888", "text": "How does adolescence affect the brain's dopamine system?"}
{"id": "000889", "text": "Why is it important to understand the mechanisms underlying haemorrhagic transformations in stroke patients?"}
{"id": "000892", "text": "Which is the recommended post-stroke ischemic induction protocol?"}
{"id": "000893", "text": "What is unknown about mindfulness-based treatments for PTSD?"}
{"id": "000894", "text": "How is decision-making difficulty measured?"}
{"id": "000895", "text": "What is the most important cause of dependence in older population?"}
{"id": "000896", "text": "Can mindfulness-based treatments be considered as first-line treatments for PTSD?"}
{"id": "000900", "text": "What methodology can be used to measure the development of ADHD symptoms in a N-of-1 trial?"}
{"id": "000901", "text": "What drives the flow of the cerebro spinal fluid through the subarachnoid region?"}
{"id": "000902", "text": "Are diffusion of water and other solutes possible in the brain in the absence of glial AQP4?"}
{"id": "000903", "text": "Why is the brain lymphatic system termed \"glymphatic system\"?"}
{"id": "000904", "text": "Are there differences in the conclusions drawn by radiologists from manual analysis of radiological images that could be reduced using systematic analysis with artificial intelligence tools?"}
{"id": "000905", "text": "Can exosomes reduce inflammation after return of normal blood flow in stroke?"}
{"id": "000906", "text": "Do Matrix Metalloproteinases (MMPs) play a causal role in ischemic stroke or stroke recovery?"}
{"id": "000907", "text": "Which artery or arterial segment has the highest risk of rupture after endovascular\ntreatment?"}
{"id": "000909", "text": "In patients with active intracranial hemorrhage after endovascular treatment, which\nbleeding duration has the worse outcome?"}
{"id": "000910", "text": "What is a hemorrhagic transformation?"}
{"id": "000911", "text": "What treatments are available for Alzheimer's disease?"}
{"id": "000912", "text": "According to clinical trials, what is the ideal blood pressure to improve the prognosis of patients with cerebral hemorrhage?\nprognosis of patients with cerebral hemorrhage?"}
{"id": "000914", "text": "How does Alzheimer's disease affect memory?"}
{"id": "000916", "text": "Can treatment with NF-KB inhibitors increase the risk of infections?"}
{"id": "000918", "text": "What are the different factors contributing to the development of augmentation syndrome in restless legs syndrome?"}
{"id": "000920", "text": "What is the role of netrin-1 in dopamine neuron development?"}
{"id": "000921", "text": "To analyze CT scans with machine learning, can we use raw images directly, or do we need a doctor to pre-process them first?"}
{"id": "000922", "text": "Is there a relationship between astrocytes and trigeminal neuralgia?"}
{"id": "000923", "text": "What is DCC and why is it important?"}
{"id": "000924", "text": "What is known about the mechanisms of brainstem microcircuitry in orofacial pain?"}
{"id": "000925", "text": "Are exosomes a potential treatment in stroke?"}
{"id": "000928", "text": "Is there any possible adverse effect of endovascular treatment in acute ischemic stroke?"}
{"id": "000929", "text": "How does stress affect the brain's dopamine system?"}
{"id": "000933", "text": "Does having less DCC affect behavior?"}
{"id": "000934", "text": "Can reperfusion treatments after a stroke decline the prognosis for stroke patients in some situations?"}
{"id": "000935", "text": "How does the immune system change with ageing?"}
{"id": "000936", "text": "What is the histologic architecture of the meningeal lymphatic system?"}
{"id": "000938", "text": "What are the current research directions in Alzheimer's disease treatment?"}
{"id": "000939", "text": "Is inflammation relevant in the AD pathology?"}
{"id": "000940", "text": "What is mindfulness-based stress reduction?"}
{"id": "000942", "text": "Do you have a list of modificable risk factors for hemorrhagic stroke?"}
{"id": "000943", "text": "What happens to someone that has less DCC protein?"}
{"id": "000944", "text": "How do researchers use MRI to study brain structure in mice?"}
{"id": "000946", "text": "Are miRNA contained in neuronal exosomes regulating important features in stroke?"}
{"id": "000947", "text": "What is the association between the cardiac cycle and the CSF flow?"}
{"id": "000948", "text": "Why should we invest in the study of stroke?"}
{"id": "000949", "text": "What are the mechanisms by which inflammatory processes induce damage in the brain after a stroke?"}
{"id": "000950", "text": "What is the anatomical distribution of meningeal lymphatic system?"}
{"id": "000951", "text": "How could I classify the severity of a brain artery rupture after endovascular\ntreatment?"}
{"id": "000952", "text": "How do mindfulness-based treatments compare to traditional therapies for PTSD?"}
{"id": "000957", "text": "How can we assess the status of a patient after a stroke?"}
{"id": "000958", "text": "What is the pathophysiology of trigeminal neuralgia?"}
{"id": "000959", "text": "What is the Mendelian Randomization (MR) technique used for?"}
{"id": "000960", "text": "What increases the predisposition to hemorrhagic transformation occurrence after suffering an ischemic stroke?"}
{"id": "000961", "text": "How to reduce the risk of losing physiological regulation of blood pressure to\nmaintain normal cerebral blood flow in acute stroke patients who underwent endovascular\ntreatment?"}
{"id": "000965", "text": "can the exosomes be useful for stroke diagnosis?"}
{"id": "000966", "text": "How does technology help in understanding psychiatric disorders?"}
{"id": "000967", "text": "How do amyloid β peptides and tau protein interact in Alzheimer's disease?"}
{"id": "000968", "text": "Do patients with Alzheimer's disease have problems to do normal tasks such as cooking or driving?"}
{"id": "000969", "text": "What is the role of meningeal lymphatics related to central nervous system immunity?"}
{"id": "000970", "text": "Are there any epigenetic modifications known to play a role in the pathogenesis of Alzheimer's disease?"}
{"id": "000972", "text": "What is the most recommended treatment of a brain artery rupture after\nendovascular treatment?"}
{"id": "000973", "text": "What is the best radiological predictor of malignant stroke when a patient with acute ischemic stroke is treated with an endovascular procedure?"}
{"id": "000974", "text": "Do symptomatic virus or bacterial contagions have any role in the incidence of\nacute cerebral infarcts with large vessel occlusion?"}
{"id": "000976", "text": "What is mindfulness in PTSD patient treatment?"}
{"id": "000977", "text": "What is trigeminal neuralgia?"}
{"id": "000980", "text": "Can mindfulness help reduce PTSD symptoms?"}
{"id": "000981", "text": "Which are the known factors or mechanisms associated to affect the CSF flow?"}
{"id": "000983", "text": "Why do people with depression avoid rewarding activities?"}
{"id": "000984", "text": "Can all strokes be treated effectively with the same approach?"}
{"id": "000985", "text": "Can exosomes isolated from blood provide information about brain molecular processes ?"}
{"id": "000986", "text": "What is the role of amyloid β in Alzheimer's disease?"}
{"id": "000988", "text": "What is the significance of glutamate in Alzheimer's disease?"}
{"id": "000989", "text": "How do high blood glucose levels affect the stroke?"}
{"id": "000990", "text": "Can a cranial perfusion CT help predict a malignant stroke?"}
{"id": "000991", "text": "What are the challenges in using exposure-based therapies for PTSD?"}
{"id": "000992", "text": "What criteria are used to select the SNPs used for Mendelian randomization (MR) analysis?"}
{"id": "000995", "text": "What information does the NIHSS provide regarding stroke prognosis?"}
{"id": "000998", "text": "What is netrin-1 and what role does it play in the brain?"}
{"id": "001001", "text": "What are the advantages of using suture tape in ankle ligament reconstruction?"}
{"id": "001005", "text": "What is the typical recovery protocol following total ankle arthroplasty?"}
{"id": "001008", "text": "What are the main consequences that can arrive from damaging the ankle syndesmosis?"}
{"id": "001009", "text": "What is the incidence of ankle syndesmotic injury?"}
{"id": "001010", "text": "What are the fundamental aspects required for the successful adoption of the PARS program?"}
{"id": "001012", "text": "What is the AO/OTA classification for trimalleolar fractures?"}
{"id": "001014", "text": "What is the recommended conservative protocol for acute injuries of the ankle syndesmosis without instability?"}
{"id": "001016", "text": "What is the recommended treatment for unstable subacute syndesmotic ankle sprains?"}
{"id": "001017", "text": "What is the PARS program?"}
{"id": "001023", "text": "Why do people undergo an arthroscopic bone marrow stimulation?"}
{"id": "001025", "text": "What are the clinical implications of different TMT1 morphologies in hallux valgus?"}
{"id": "001027", "text": "In what ways did the PARS program contribute to a decrease in malpractice?"}
{"id": "001030", "text": "How long does it usually take before you might need another surgery for an ankle injury?"}
{"id": "001031", "text": "What are the indications for using the BHR implant?"}
{"id": "001032", "text": "What is the role of LCL of the ankle?"}
{"id": "001039", "text": "What factors influence the likelihood of BHR implant failure?"}
{"id": "001040", "text": "What are the main advantages argued for performing external fixation instead of intramedullary nails of the femur in patients with multiple trauma in the emergency setting?"}
{"id": "001042", "text": "How are patient complaints categorized in the PARS program?"}
{"id": "001043", "text": "In a critical emergency patient with a Gustilo III femur fracture, does external fixation add any advantage over early intramedullary nail fixation?"}
{"id": "001047", "text": "What are the complications of ankle arthroplasty?"}
{"id": "001048", "text": "Why would someone need an Achilles tendon lengthening procedure?"}
{"id": "001049", "text": "What are the potential risks of using cement in knee implants?"}
{"id": "001051", "text": "Is it frequent to recover full range of motion and strength after suffering a brachial plexus injury?"}
{"id": "001052", "text": "What is a syndesmotic injury of the leg?"}
{"id": "001054", "text": "What is the recommended treatment for unstable acute syndesmotic ankle sprains?"}
{"id": "001055", "text": "In a patient that suffered an episode of multiple traumatic and severe injuries and an open comminuted fracture with a skin defect, would an intramedullary nail be recommended as a fracture treatment in the acute phase?"}
{"id": "001056", "text": "What are the sustained outcomes of total ankle arthroplasty using prostheses?"}
{"id": "001058", "text": "What is the advantage of MRI when ruling out injuries of the ankle syndesmosis?"}
{"id": "001062", "text": "What are the clinical advantages of BHR over total hip arthroplasty?"}
{"id": "001063", "text": "What are the main factors influencing the selection of surgical technique for the repair of trimalleolar fractures?"}
{"id": "001066", "text": "What are the advantages of locking plates when treating lateral malleolus fractures?"}
{"id": "001067", "text": "Is there a clear and consensual treatment for syndesmotic injuries of the ankle?"}
{"id": "001073", "text": "What is the most recommended classification for trimalleolar fractures?"}
{"id": "001078", "text": "When should a syndesmotic injury of the ankle be treated surgically?"}
{"id": "001082", "text": "What ligaments form the tibio-peroneal syndesmosis?"}
{"id": "001083", "text": "Does the patient have to choose the type of prosthesis he will have?"}
{"id": "001084", "text": "Why do some people get cementless knee implants?"}
{"id": "001085", "text": "What is the benefit of the suture-button fixation technique for the treatment of unstable acute syndesmotic ankle sprains ?"}
{"id": "001086", "text": "What are the most frequent functional disabilities of patients suffering brachial plexus injuries even after undergoing reconstruction?"}
{"id": "001087", "text": "What is the prognosis of acute syndesmotic ankle sprains without instability?"}
{"id": "001089", "text": "Can I play sports after getting a BHR implant?"}
{"id": "001090", "text": "What are the recommended medical imaging modalities for syndesmotic injuries of the ankle diagnosis?"}
{"id": "001091", "text": "What factors can lead to a higher risk of BHR implant failure?"}
{"id": "001092", "text": "What complications can be associated with total ankle arthroplasty?"}
{"id": "001093", "text": "What does 'DBM' stand for?"}
{"id": "001094", "text": "What are the benefits of having a PARS program in a medical practice?"}
{"id": "001095", "text": "In which situations is an external fixator a possible option for management of a trimalleolar fracture?"}
{"id": "001099", "text": "What are the implications of sesamoid position in hallux valgus recurrence?"}
{"id": "001100", "text": "What it the best muscle transfer for the recovery of shoulder abduction after long term brachial plexus injury?"}
{"id": "001105", "text": "Are there any specific groups of patients who have better outcomes with the BHR implant?"}
{"id": "001106", "text": "How can you evaluate if a patient will repeat the same intervention that had previously received as a measure of satisfaction with that intervention?"}
{"id": "001108", "text": "What is the indication for a posterior malleolus fixation in trimalleolar fractures?"}
{"id": "001109", "text": "What are the risks of nonunion in ankle arthrodesis?"}
{"id": "001115", "text": "Which is the period of time where surgeons should be more vigilant of the status of the wounds and joint symptoms after a TKA?"}
{"id": "001117", "text": "What can happen if you get a forefoot ulcer?"}
{"id": "001119", "text": "What are the articular and anatomic relations of the talus?"}
{"id": "001121", "text": "Between external fixation and intramedullary nail, which is the best treatment for a comminuted fracture in terms of reducing the need for critical care in a polytrauma patient?"}
{"id": "001123", "text": "What is the disadvantage of performing external fixation of an ipsilateral femur and tibia fracture?"}
{"id": "001124", "text": "What is the normal range of motion of the ankle in the sagittal plane?"}
{"id": "001125", "text": "Can ankle problems come back even after surgery?"}
{"id": "001127", "text": "What are the recommended views that radiographic imaging should include for the diagnosis of injuries of the ankle syndesmosis?"}
{"id": "001128", "text": "What are the main roles of every ankle ligament in the stabilization of the ankle?"}
{"id": "001131", "text": "What are the preferred tests for diagnosis of ankle syndesmosis?"}
{"id": "001132", "text": "How are patient complaints used to identify high-risk clinicians in the PARS program?"}
{"id": "001135", "text": "What is the recommended location of the screws to be placed for the treatment of unstable acute syndesmotic ankle sprains?"}
{"id": "001138", "text": "How long should a patient who received screws for the treatment of an unstable acute syndesmotic ankle sprain wait until full-weight bearing?"}
{"id": "001139", "text": "What is the generally recommended treatment for ankle fractures involving the posterior malleolus?"}
{"id": "001140", "text": "What components form the tibiofibular ligamentous complex?"}
{"id": "001144", "text": "What is total ankle arthroplasty?"}
{"id": "001147", "text": "What is the most frequently used technique to treat unstable acute syndesmotic ankle sprains?"}
{"id": "001149", "text": "What difficulties are encountered when utilizing cellular bone matrices?"}
{"id": "001153", "text": "What is the expected improvement of shoulder abduction and external rotation after lower trapezius muscle transfer in brachial plexus injury patients?"}
{"id": "001156", "text": "What is the recommended surgical technique for trimalleolar fractures in patients with osteoporosis?"}
{"id": "001158", "text": "How long does it take for patients suffering acute syndesmotic ankle sprains without instability to return to normal activity?"}
{"id": "001160", "text": "What is the evidence based recommended size and number of screws for the treatment of unstable acute syndesmotic ankle sprains?"}
{"id": "001162", "text": "Is there a classification system for posterior malleolus fractures?"}
{"id": "001166", "text": "How do the fusion rates compare among the different graft types used?"}
{"id": "001169", "text": "What are the demographic factors associated with forefoot ulcer development ?"}
{"id": "001173", "text": "What is the surgical treatment of recurrent prosthetic joint infection that carries the lowest risk of mortality?"}
{"id": "001180", "text": "Can Achilles tendon lengthening help prevent ulcers?"}
{"id": "001181", "text": "Which is the indication for an postero-lateral approach in posterior malleolus fractures?"}
{"id": "001183", "text": "How long should a patient who received suture-button fixation for the treatment of an unstable acute syndesmotic ankle sprain wait until full-weight bearing?"}
{"id": "001188", "text": "When can a syndesmotic injury of the ankle be treated conservatively?"}
{"id": "001191", "text": "Which surgery is Achilles tendon lengthening often associated with?"}
{"id": "001192", "text": "What are the primary and secondary outcomes measured in studies of arthroscopic BMS for OLT?"}
{"id": "001194", "text": "What are the advantages of intramedullary nails compared to standard plate ORIF for lateral malleolus fractures?"}
{"id": "001195", "text": "How does the BHR implant compare to total hip arthroplasty?"}
{"id": "001197", "text": "Do risk factors for knee arthroplasty infection change depending on the timing of infection?"}
{"id": "001200", "text": "When is the posteromedial approach useful in malleolar fractures?"}
{"id": "001201", "text": "Why does weight gain associate to OSAS?"}
{"id": "001202", "text": "Which are the main sleep questionnaires used for the diagnosis of OSAS?"}
{"id": "001203", "text": "Apart from PSG, are there other test that can be used for the diagnosis of OSAS?"}
{"id": "001204", "text": "What is the best surgical treatment for obstructive sleep apnea?"}
{"id": "001205", "text": "Which sedating agent is recommended for DISE?"}
{"id": "001210", "text": "Which are the risk factors associated with inferior position of the hyoid bone?"}
{"id": "001211", "text": "What is the impact of maxillo-mandibular advancement in the apnea and hypopnea index?"}
{"id": "001215", "text": "What is the success rate of TORS for obstructive sleep apnea as part of a multilevel surgical approach?"}
{"id": "001216", "text": "Which areas of the pharynx of patients with OSAS are most frequently reduced?"}
{"id": "001218", "text": "What is ruxolitinib used for?"}
{"id": "001225", "text": "What is Obstructive sleep apnea?"}
{"id": "001226", "text": "What impact did COVID-19 have on the frequency of laryngology procedures?"}
{"id": "001228", "text": "Why is MMA more successful than MLS in treating OSA?"}
{"id": "001230", "text": "What are the main findings regarding the factors associated with inadequate health literacy?"}
{"id": "001232", "text": "Can we find a trial comparing MMA and MLS in the treatment of OSA?"}
{"id": "001234", "text": "What should a nasal examination include when evaluating a patient for obstruction sleep apnea syndrome?"}
{"id": "001235", "text": "Is there an alternative hypothesis about the relation between hyoid bone position and sleep apnea?"}
{"id": "001237", "text": "Does a person's race impact their grasp of health information?"}
{"id": "001239", "text": "Is there long-term evidence of effectiveness of  hypoglossal nerve stimulation for the treatment of obstructive sleep apnea?"}
{"id": "001240", "text": "What is the value of drug-induced sedation endoscopy for obstructive sleep apnea examination?"}
{"id": "001242", "text": "What is the relation of the morphology of the palate and the tongue?"}
{"id": "001243", "text": "What are the potential risks associated with tranexamic acid?"}
{"id": "001244", "text": "What is the recommended protocol for DISE?"}
{"id": "001245", "text": "How often do doctors see chronic cough in their practice?"}
{"id": "001246", "text": "What is the long-term effect on AHI of MLS when treating OSA?"}
{"id": "001247", "text": "What is the main test for diagnosis of OSAS?"}
{"id": "001249", "text": "What are some common conditions treated with laryngology procedures?"}
{"id": "001251", "text": "What role does insurance type play in health literacy?"}
{"id": "001252", "text": "What is the effectiveness of maxillomandibular advancement in the treatment of OSA?"}
{"id": "001254", "text": "What were the common diagnoses leading to laryngology procedures during COVID-19?"}
{"id": "001256", "text": "If we divided MLS surgical techniques for sleep apnea syndrome into three levels based on the target structures, which type of surgery would provide the most benefit?"}
{"id": "001258", "text": "What should a physical examination include to correctly evaluate obstructive apnea disorder?"}
{"id": "001259", "text": "Why is it difficult to diagnose GPA?"}
{"id": "001260", "text": "Which factors are associated with a higher rate of complications of surgical treatment of OSA?"}
{"id": "001264", "text": "What is the success rate of upper airway stimulation when treating OSA?"}
{"id": "001265", "text": "What is the DISE classification to characterize the findings during the evaluation?"}
{"id": "001267", "text": "What is unexplained chronic cough?"}
{"id": "001268", "text": "Is there a pattern of collapse that is a predictor of failure of MMA in the treatment of OSA?"}
{"id": "001269", "text": "What led to the increase in laryngology procedures during the pandemic?"}
{"id": "001270", "text": "What is the most effective surgical treatment option for OSA?"}
{"id": "001271", "text": "Which subgroup (by target levels of treatment) is associated with a higher success of MLS in treating OSA?"}
{"id": "001273", "text": "Which test should be performed to evaluate the upper airway anatomy?"}
{"id": "001275", "text": "What is the gold-standard of OSA?"}
{"id": "001276", "text": "What were the effects of COVID-19 on patients needing laryngology procedures?"}
{"id": "001278", "text": "What should be done if GPA is suspected but tests are negative?"}
{"id": "001279", "text": "What were the clinical implications of the increase in laryngology procedures during the pandemic?"}
{"id": "001280", "text": "What are some common effects of chronic cough on a person's life?"}
{"id": "001281", "text": "What is DISE?"}
{"id": "001282", "text": "Is nasal breathing associated with obstructive sleep apnea?"}
{"id": "001286", "text": "Are there any facial morphologic features that are characteristic of sleep apnea syndrome?"}
{"id": "001288", "text": "How does limited understanding of health information impact patient care?"}
{"id": "001289", "text": "What is the Epworth Sleeping Scale?"}
{"id": "001291", "text": "What is the role of nasal surgery in the treatment plan for obstructive sleep apnea?"}
{"id": "001292", "text": "What happens during sleep in patients suffering OSA?"}
{"id": "001293", "text": "Which are the selection criteria for a patient to become a candidate for selective nerve stimulation to treat obstructive sleep apnea?"}
{"id": "001294", "text": "Are there any new treatments against chronic cough?"}
{"id": "001296", "text": "Which are the main predictors of failure of soft tissue surgical treatment of obstructive sleep apnea?"}
{"id": "001297", "text": "Which are the main osseous structures that should be evaluated for the diagnosis and categorization of a patient with sleep apnea before the indication for a maxillo-mandibular advancement?"}
{"id": "001298", "text": "What were the key reasons for the shift to more office-based laryngology procedures during the pandemic?"}
{"id": "001299", "text": "What is the success rate of MMA when treating OSA?"}
{"id": "001301", "text": "How are patients evaluated for HGNS?"}
{"id": "001303", "text": "Is it important to measure the location of the hyoid bone in relation to the mandible when considering orthognathic surgery for patients with sleep apnea?"}
{"id": "001304", "text": "What kind of treatments are used for chronic cough?"}
{"id": "001305", "text": "Is there a test or an exam that can predict the success orthognathic surgery for the treatment of obstructive sleep apnea syndrome?"}
{"id": "001307", "text": "What is the role of Oxygen Desaturation Index in the evaluation of obstructive sleep apnea?"}
{"id": "001308", "text": "How did the pandemic affect the number of laryngology procedures?"}
{"id": "001309", "text": "Is there a maneuver during endoscopic examination that can effectively evaluate upper airway collapsability?"}
{"id": "001315", "text": "What are the advantages of using cephalometric examination as a diagnostic tool for OSA?"}
{"id": "001316", "text": "What is the significance of c-ANCA in diagnosing GPA?"}
{"id": "001318", "text": "What is multilevel surgery when talking about OSA?"}
{"id": "001320", "text": "What is the main surgical option available for OSA patients with CCCp pattern of collapse?"}
{"id": "001323", "text": "What is the main test for diagnosis of obstructive sleep apnea?"}
{"id": "001325", "text": "How can maxillomandibular advancement decrease the severity of OSAS?"}
{"id": "001326", "text": "Is uvulopalatopharingoplasty an effective surgery for obstructive sleep apnea?"}
{"id": "001329", "text": "Did the pandemic cause any delays in laryngology procedures?"}
{"id": "001330", "text": "What is the logic behind neural stimulation for obstructive sleep apnea treatment?"}
{"id": "001331", "text": "What is the role of the hyoid bone in the respiratory system?"}
{"id": "001333", "text": "What is the volumetric change of the upper airway obtained after MLS in OSA patients?"}
{"id": "001334", "text": "Is MLS or MMA considered safe options for the treatment of OSA?"}
{"id": "001335", "text": "What is the effectiveness of the selective nerve stimulation therapy for obstructive sleep apnea?"}
{"id": "001336", "text": "Are maxillomandibular advancement and upper airway nerve stimulation compatible treatments for obstructive sleep apnea in the same patient?"}
{"id": "001338", "text": "How can a patient's health literacy be determined?"}
{"id": "001339", "text": "How frequently do patients struggle to understand medical information?"}
{"id": "001341", "text": "Is there a known level of the airway where collapse is a prognosticator of failure of MMA in the treatment of OSA?"}
{"id": "001342", "text": "What is the role of genioplasty advancement for the treatment of obstructive sleep apnea?"}
{"id": "001344", "text": "What are the potential benefits of using tranexamic acid in surgical patients with hematological malignancies?"}
{"id": "001346", "text": "What imaging techniques are used to assess nasal abscesses?"}
{"id": "001347", "text": "Are there anatomic differences in the upper airway of males and females?"}
{"id": "001348", "text": "What is the effectiveness of MMA as a treatment for OSAS?"}
{"id": "001349", "text": "Which surgical treatment of OSA is associated with a higher success rate of improving subjective feelings?"}
{"id": "001350", "text": "Which are the most frequent viruses known to produce infections during colder months?"}
{"id": "001352", "text": "What is the OSAS?"}
{"id": "001354", "text": "What are the functions of the inferior turbinates?"}
{"id": "001356", "text": "What are common causes of abscesses in the nasal cavity?"}
{"id": "001358", "text": "What are the main factors associated to affect the long-term success of MLS when treating OSA?"}
{"id": "001359", "text": "Which is the most effective surgical treatment of obstructive sleep apnea?"}
{"id": "001361", "text": "Which are the main determinants for success of MMA as a treatment for obstructive sleep apnea?"}
{"id": "001364", "text": "How did the pandemic affect the types of laryngology procedures performed?"}
{"id": "001367", "text": "How to assess the swallowing quality of patients?"}
{"id": "001371", "text": "What is the role of upper airway surgery for OSA treatment?"}
{"id": "001372", "text": "Is ambulatory sleep testing equivalent to polysomnography for the evaluation of obstructive sleep apnea?"}
{"id": "001373", "text": "Which are the main causes that lead to OSAS?"}
{"id": "001374", "text": "Is there a way to objectively measure improvement in a patient with sleep apnea syndrome after maxillomandibular advancement?"}
{"id": "001375", "text": "Which are the main indications for MMA in the algorithm of treatment of obstructive sleep apnea?"}
{"id": "001376", "text": "Do women have better smell sense than men?"}
{"id": "001378", "text": "Which DISE patterns from the VOTE classification are more associated with obstructive sleep apnea?"}
{"id": "001379", "text": "Is there a surgical solution for relentless soft palate obstruction after upper airway stimulation surgery where there is absence of velar-lingual synchronization?"}
{"id": "001382", "text": "Were laryngology procedures disrupted during the COVID-19 pandemic?"}
{"id": "001383", "text": "What would be the subgroup of patients with sleep apnea syndrome that would benefit the most from a maxillomandibular advancement?"}
{"id": "001384", "text": "Can the type of insurance people have be a factor of health literacy?"}
{"id": "001385", "text": "Which type of non-MMA multi-level surgical treatment has a higher success rate when treating MMA?"}
{"id": "001386", "text": "What are the official recommended treatments for chronic cough?"}
{"id": "001387", "text": "What is the rationale behind maxillomandibular advancement for the treatment of obstructive sleep apnea?"}
{"id": "001388", "text": "What is the AHI in the field of OSA?"}
{"id": "001391", "text": "Which are the main target nerves for neural stimulation for the treatment of obstructive sleep apnea?"}
{"id": "001392", "text": "Which are the most common viruses associated to infect patients in warmer months?"}
{"id": "001393", "text": "What is the advantage of the ESS as sleep questionnaire?"}
{"id": "001394", "text": "Is it necessary to perform a drug-induced sleep endoscopy before performing a hypoglossal nerve stimulation in the Netherlands?"}
{"id": "001395", "text": "What is the volumetric change of the upper airway obtained when treating OSA with MMA?"}
{"id": "001396", "text": "What is the long-term follow-up recommendation for patients who sustained a surgical treatment for OSA?"}
{"id": "001397", "text": "What is the association between hyoid bone position and OSAS?"}
{"id": "001398", "text": "What laboratory findings are associated with nasal abscesses?"}
{"id": "001399", "text": "What is the effect of the upper stimulation system in the upper airway to provide a relief from obstructive apnea?"}
{"id": "001400", "text": "What is the recommended algorithm of surgical treatment of OSA?"}
{"id": "001402", "text": "What should be considered before deciding on surgery for calcinosis cutis?"}
{"id": "001405", "text": "Which are the benefits of topical therapy for non-melanoma skin cancer?"}
{"id": "001406", "text": "In the cosmetic field, what is a \"filler\"?"}
{"id": "001407", "text": "What are the risks of choosing the wrong vessels for a flap?"}
{"id": "001408", "text": "Why do doctor use skin grafting in scalp reconstruction?"}
{"id": "001409", "text": "What genetic marker is commonly found in desmoid tumors?"}
{"id": "001410", "text": "What are the indications for using a free vascularized fibula graft in spinal surgery?"}
{"id": "001412", "text": "What surgical techniques are involved in the placement of a vascularized fibula graft?"}
{"id": "001414", "text": "What does it mean for a plastic surgeon to have a leadership position?"}
{"id": "001418", "text": "What is the surgical margin recommended for the standard surgical excision of non-melanoma skin cancer in the absence of Mohs surgery?"}
{"id": "001419", "text": "What is the indication for external fixator in the absence of bone instability after debridement of lower limbs with osteomyelitis?"}
{"id": "001421", "text": "Which is the recommended flap of choice for lower limb osteomoyelitis reconstruction?"}
{"id": "001424", "text": "What is the mechanism of action of photodynamic therapies for the treatment of non-melanoma skin cancer?"}
{"id": "001425", "text": "How can calcinosis cutis be treated?"}
{"id": "001432", "text": "What is the usual prophylactic treatment to avoid post-operative deep venous thrombosis?"}
{"id": "001433", "text": "How is a saphenous vein graft used in surgery?"}
{"id": "001434", "text": "Is there evidence to support earlier repair of ankyloglossia that improves the duration and effectiveness of breastfeeding?"}
{"id": "001440", "text": "What is the indication for achieving stability in osteomyelitis type IV if the defect is large or the soft tissues prevent acute compression?"}
{"id": "001443", "text": "What is the therapeutic plan for a patient that is diagnosed of a distal deep venous thrombosis?"}
{"id": "001447", "text": "When is the ergotrid flap a suitable reconstructive option?"}
{"id": "001448", "text": "What alternative recipient vessels can be considered if the internal mammary vessels are inadequate?"}
{"id": "001449", "text": "What is the main strategy for the treatment of primary melanoma?"}
{"id": "001450", "text": "What is the significance of the CTNNB1 mutation in desmoid tumors?"}
{"id": "001454", "text": "What are the common treatment options for desmoid tumors?"}
{"id": "001455", "text": "How is osteomyelitis treated?"}
{"id": "001456", "text": "What are the recommended margins of safe wide excision depending on the depth of the primary melanoma?"}
{"id": "001457", "text": "What are the results of venous doppler monitoring as flap monitoring method for head an neck, breast and lower limb free flap reconstruction?"}
{"id": "001460", "text": "Which are the best recipient vessels for tibial free flap reconstruction?"}
{"id": "001461", "text": "What is osteomyelitis?"}
{"id": "001463", "text": "What is the recommended management after a finding a suspicious lymph node?"}
{"id": "001469", "text": "What is the recommended management in case of local recurrence in patients treated by conventional surgical excision for a non-melanoma skin cancer?"}
{"id": "001471", "text": "Which is the indication of negative pressure wound therapy in lower limb acute trauma surgical management?"}
{"id": "001472", "text": "What is the role of 3D virtual surgical planning in the treatment of desmoid tumors?"}
{"id": "001475", "text": "Is there a situation where it is most beneficial to use topical therapies in non-melanoma skin cancer in the absence of Mohs micrographic surgery?"}
{"id": "001476", "text": "What are the implications of repeated BTA injections in terms of immunoreaction?"}
{"id": "001477", "text": "Why is the latissimus dorsi muscle chosen for scalp reconstruction?"}
{"id": "001478", "text": "What medical interventions can be necessary after a major scalp injury?"}
{"id": "001480", "text": "When is sentinel lymph node biopsy considered in patients suffering melanoma?"}
{"id": "001481", "text": "Which are the goals of flap coverage in osteomyelitis of the lower limb?"}
{"id": "001484", "text": "When is secondary intention a good option for reconstruction in non-melanoma skin cancer?"}
{"id": "001485", "text": "What is the treatment for iatrogenic facial nerve neuroapraxia after facelifting procedure?"}
{"id": "001486", "text": "Is surgery the only option for treating calcinosis cutis?"}
{"id": "001488", "text": "What is the risk of a second skin tumor after a primary non-melanoma skin cancer?"}
{"id": "001490", "text": "What is a DIEP flap used for?"}
{"id": "001494", "text": "Which are the main treatments available for ankyloglossia?"}
{"id": "001495", "text": "What is the most usual treatment for permanent cosmetic fillers' negative reactions?"}
{"id": "001496", "text": "What are the main findings regarding the recurrence rate in mastectomy scars?"}
{"id": "001497", "text": "Is there a situation where it is most beneficial to use brachytherapy in non-melanoma skin cancer in the absence of Mohs micrographic surgery?"}
{"id": "001498", "text": "What is the recommended surgical technique for frenotomy of patients over 3 months of age suffering ankyloglossia?"}
{"id": "001502", "text": "Why can the vessels chosen for a flap not be suitable?"}
{"id": "001503", "text": "What is the recommended image modality to assess the lymphatic draining and pathways in search of in-transit disease of melanoma when the physical exam is equivocal?"}
{"id": "001506", "text": "What is done if there is venous congestion during surgery?"}
{"id": "001507", "text": "Can permanent cosmetic fillers be any harmful?"}
{"id": "001508", "text": "What are the potential complications of cervical osteomyelitis surgery?"}
{"id": "001510", "text": "What is the efficacy of ultrasound or venography for the diagnosis of venous thromboembolism?"}
{"id": "001512", "text": "What happens after the muscle flap and skin graft heal?"}
{"id": "001513", "text": "What are the causes of facial aging?"}
{"id": "001514", "text": "Which are the inconveniences and benefits of curettage for non-melanoma skin cancer?"}
{"id": "001515", "text": "Which are the known risk factors for complete or partial necrosis of propeller flaps in lower limb extremity defects?"}
{"id": "001516", "text": "When is it recommended providing a reconstruction of skin defects with biologic wound agents?"}
{"id": "001522", "text": "Which scenarios advocate best for full thickness vs split thickness skin graft in the reconstruction of skin defects?"}
{"id": "001523", "text": "Can BTA injection have any side effects?"}
{"id": "001524", "text": "What are the key factors to consider before choosing a free vascularized fibula graft for spinal reconstruction?"}
{"id": "001529", "text": "What is the mechanism of action of topical therapies for the treatment of non-melanoma skin cancer?"}
{"id": "001532", "text": "What are the essential procedures for reconstructing significant scalp loss?"}
{"id": "001533", "text": "What are the challenges in treating pediatric desmoid tumors?"}
{"id": "001534", "text": "What is the recommended management in case of positive margins in patients treated by conventional surgical excision for a non-melanoma skin cancer?"}
{"id": "001535", "text": "Which are the inconveniences of topical therapy for non-melanoma skin cancer?"}
{"id": "001536", "text": "What is the recommended surgical technique for frenotomy of patients under 3 months of age suffering ankyloglossia?"}
{"id": "001537", "text": "Is there scientific evidence of the benefits of frenotomy in patients suffering ankyloglossia?"}
{"id": "001545", "text": "What is the effectiveness of the photodynamic therapy when treating non-melanoma skin cancer?"}
{"id": "001547", "text": "Which is the indication of negative pressure wound therapy in lower limb osteomyelitis surgical management?"}
{"id": "001548", "text": "When is deep pelvic ilio-inguinal dissection recommended in groin lymphadenectomy of melanoma patients?"}
{"id": "001550", "text": "What is the most effective surgical technique for ankyloglossia repairs?"}
{"id": "001551", "text": "What is a desmoid tumor?"}
{"id": "001552", "text": "What follow-up care is needed after flap surgery?"}
{"id": "001553", "text": "What are the signs that a flap surgery was successful?"}
{"id": "001557", "text": "What are the obstacles in reconstructing the cervical spine after an infection?"}
{"id": "001558", "text": "Is it necessary to treat distal thrombosis?"}
{"id": "001561", "text": "What are the main diagnostic uses of ultrasound in plastic surgery?"}
{"id": "001565", "text": "Can BTA injections affect areas other than where they were injected?"}
{"id": "001566", "text": "Are there any non-surgical treatments for calcinosis cutis?"}
{"id": "001568", "text": "What is the benefit of ultrasound screening for distal venous thrombosis?"}
{"id": "001574", "text": "What are the benefits of surgical repair of ankyloglossia?"}
{"id": "001577", "text": "Which are the options for dead space management in patients with lower limb osteomyelitis?"}
{"id": "001579", "text": "Intravenous vs oral antibiotic therapy, which of these shows better results when treating osteomyelitis?"}
{"id": "001580", "text": "What can contribute to a higher likelihood of a plastic surgeon assuming a leadership role?"}
{"id": "001584", "text": "What is the main risk of having deep venous thrombosis?"}
{"id": "001585", "text": "Which are the inconveniences and benefits of photodynamic therapy for non-melanoma skin cancer?"}
{"id": "001586", "text": "What is the benefit of ultrasound-guided thoracic paravertebral blocks in breast reduction patients?"}
{"id": "001589", "text": "Is there a significant relationship between the timing of breast reconstruction and the recurrence of cancer?"}
{"id": "001592", "text": "What are the risks of reconstructing a breast after mastectomy?"}
{"id": "001596", "text": "What are the indicators of successful venous drainage in flap surgery?"}
{"id": "001599", "text": "Is there a situation where it is most beneficial to use chemotherapy in non-melanoma skin cancer in the absence of Mohs micrographic surgery?"}
{"id": "001601", "text": "Has the HOP program been adapted for different groups of people?"}
{"id": "001602", "text": "What are the interpersonal and social mechanisms behind violent pathological behavior?"}
{"id": "001603", "text": "How can athletes learn more quickly and effectively during training sessions?"}
{"id": "001607", "text": "Is it possible to assess the prognosis of dementia management in advance?"}
{"id": "001608", "text": "Is there a significant treatment gap in mental health?"}
{"id": "001609", "text": "How do perceived social support and coping style mediate the relationship between patients' psychological state and quality of life?"}
{"id": "001610", "text": "Can someone's social skills before getting sick predict if their psychosis will be hard to treat?"}
{"id": "001612", "text": "What happens socially when mental illnesses are not treated?"}
{"id": "001613", "text": "Why is mental health research important?"}
{"id": "001614", "text": "What is the relationship between the risks inherent in farming, associated stress levels and mental well-being among women farmers, taking gender differences into account?"}
{"id": "001615", "text": "How does stigma affect individuals with mental health issues?"}
{"id": "001617", "text": "How could the HOP program be improved?"}
{"id": "001618", "text": "Can the MoCA test be used for screening assessment of the cognitive status of stroke patients?"}
{"id": "001621", "text": "What factors might interfere with the psychological well-being of working women?"}
{"id": "001622", "text": "How does the use of machine learning contribute to understanding treatment-resistant psychosis?"}
{"id": "001623", "text": "Does smoking cannabis affect the risk of treatment-resistant psychosis?"}
{"id": "001624", "text": "What are the key components of the HOP program?"}
{"id": "001625", "text": "Is there a connection between pre-disease IQ and the likelihood of treatment-resistant psychosis?"}
{"id": "001628", "text": "Why do people with mental health issues don't talk about their problems?"}
{"id": "001629", "text": "How do mothers with mental illness manage the perception of their maternal role and use discursive strategies to counter the negative stereotypes associated with their condition?"}
{"id": "001630", "text": "How do mothers with mental illness use discursive strategies to dissociate themselves from the stigmatized behaviors associated with their condition and assert their identity as responsible mothers?"}
{"id": "001632", "text": "How do genetic studies contribute to the prognosis of psychiatric disorders?"}
{"id": "001633", "text": "What is the global prevalence of major mental health conditions?"}
{"id": "001634", "text": "Does immediate feedback during executive function stimulation exercises increase sports performance?"}
{"id": "001635", "text": "How is the categorization of cancer helping for psychiatric treatment?"}
{"id": "001636", "text": "Has the suicide rate decreased in the past years?"}
{"id": "001638", "text": "Which psychological profile is most often affected by online abuse victimization in the context of romantic relationships?"}
{"id": "001643", "text": "Why is the presence of a raison d'être important to an individual's health?"}
{"id": "001644", "text": "What does it mean when someone has treatment-resistant psychosis?"}
{"id": "001646", "text": "How do mothers with mental illness use the concept of \"normality\" to position themselves in relation to the stereotypes associated with their condition and their maternal role?"}
{"id": "001648", "text": "What is the limit of ketamine's antidepressant effect in the treatment of treatment-resistant depression?"}
{"id": "001649", "text": "What outcomes have been observed from the HOP program?"}
{"id": "001650", "text": "In which situations is the MoCA test suitable for assessing the cognitive status of stroke patients?"}
{"id": "001652", "text": "How can the diversity of etiologies of violence in psychotic patients influence their therapeutic management?"}
{"id": "001654", "text": "Is the influence of genetic factors on the risk of depression comparable to other psychiatric diseases?"}
{"id": "001655", "text": "How can lithium affect suicide rates?"}
{"id": "001657", "text": "What are the therapeutic implications of applying the long-term needs prediction model in dementia?"}
{"id": "001658", "text": "How can categorising suicidal thoughts and behaviors aid in treatment?"}
{"id": "001659", "text": "Do psychiatric and neurological disorders share a common neural pathophysiology?"}
{"id": "001660", "text": "What are genome-wide association studies?"}
{"id": "001662", "text": "What can be done to improve the ability of autistic patients to cope with stressful events?"}
{"id": "001663", "text": "What psychological mechanisms can be used to reduce the incidence of cyberstalking?"}
{"id": "001664", "text": "Could dysfunction of complex networks of excitatory and inhibitory neurons be responsible for oligophrenia in psychiatric disorders?"}
{"id": "001666", "text": "Are antipsychotics efficient for people with schizophrenia?"}
{"id": "001667", "text": "What is the potential of AI in improving suicide risk assessments?"}
{"id": "001669", "text": "Can epigenetics be useful to assess the risk of drug failure in depression?"}
{"id": "001670", "text": "Can depression be diagnosed with the determination of levels of specific blood proteins?"}
{"id": "001672", "text": "Is a variation in the anatomical structure of the hippocampus involved in the onset of depressive syndrome?"}
{"id": "001674", "text": "What is the importance of monitoring the long-term cognitive status of stroke patients?"}
{"id": "001675", "text": "Does having a lower IQ mean someone is more likely to have treatment-resistant psychosis?"}
{"id": "001676", "text": "What metrics should be utilized for assessing suicidal risk?"}
{"id": "001677", "text": "What analytical approaches can be used to characterize different psychological patterns among people accused of sex crimes?"}
{"id": "001679", "text": "Could meditation techniques be as effective as psychotherapy in reducing the incidence of depression?"}
{"id": "001681", "text": "What causal link can there be between an individual's impulsive profile and their high exposure to crime?"}
{"id": "001682", "text": "How does resilience, as a psychological concept, influence the mental health of individuals working in stressful environments such as those encountered during the COVID-19 pandemic?"}
{"id": "001684", "text": "Is there a genetic basis for why some people develop treatment-resistant psychosis?"}
{"id": "001685", "text": "How can technology be used to benefit patients with neurodevelopmental disorders and improve their ability to cope with adversity?"}
{"id": "001686", "text": "What evidence supports the effectiveness of the HOP program?"}
{"id": "001687", "text": "What are the main goals of the HOP program?"}
{"id": "001689", "text": "What diagnostic criteria could be used to distinguish the various subtypes of encephalitis on the basis of their clinical manifestations?"}
{"id": "001692", "text": "What mechanisms can be used to incriminate the psychological state in the genesis of violence?"}
{"id": "001693", "text": "What is the current effectiveness of suicide risk assessments?"}
{"id": "001694", "text": "Can genetic information be used to anticipate the course of psychiatric disorders?"}
{"id": "001698", "text": "What are the sociodemographic characteristics and risk factors associated with social anxiety and social phobia in students?"}
{"id": "001700", "text": "What are the benefits of supporting disclosure in individuals with mental health issues?"}
{"id": "001703", "text": "How does antidepressant use, in combination with contextual and personal factors, influence changes in the psychological state of healthcare professionals in palliative care?"}
{"id": "001704", "text": "How do mindfulness and emotional regulation interact in a more receptive population?"}
{"id": "001706", "text": "How common is untreated mental illness?"}
{"id": "001707", "text": "What is the relationship between schizophrenia polygenic risk scores and treatment-resistant psychosis?"}
{"id": "001708", "text": "Why are funding and research for new mental health treatments decreasing?"}
{"id": "001709", "text": "Through what processes can society generate violent behavior in psychotic patients?"}
{"id": "001711", "text": "What factors are considered when analyzing the impact of lithium on suicide rates?"}
{"id": "001712", "text": "What aspects of social deprivation correlate with mental disorders and mortality?"}
{"id": "001713", "text": "What are the benefits of subclassifying illnesses?"}
{"id": "001716", "text": "What factors determine the onset of obsessive-compulsive disorders during antipsychotic treatment with clozapine?"}
{"id": "001717", "text": "What is the diagnostic relevance of LGI1-Ab-E in assessing neuropsychiatric manifestations, and how does this identification influence therapeutic strategies in the context of autoimmune encephalitis?"}
{"id": "001722", "text": "How does multi-object tracking improve performance in the prefrontal cortex?"}
{"id": "001723", "text": "What is the concept of ethical justice in research including vulnerable populations?"}
{"id": "001724", "text": "How can we reduce the prevalence of depressive symptoms in the military?"}
{"id": "001726", "text": "What is the CHADS2 calculator used for?"}
{"id": "001727", "text": "Do genetic studies help in categorizing psychiatric disorders?"}
{"id": "001730", "text": "What can increase the risk of developing treatment-resistant psychosis?"}
{"id": "001731", "text": "What is the role of genetic factors in predicting treatment-resistant psychosis?"}
{"id": "001732", "text": "Does multiple object tracking training lead to satisfactory results in terms of self-control?"}
{"id": "001734", "text": "What is the scoring range of the MoCA test?"}
{"id": "001736", "text": "What is the impact of mental health on the economy?"}
{"id": "001737", "text": "How does sensitivity to the behavior of others lead to violence?"}
{"id": "001738", "text": "What is the specific impact of different levels of ketamine administration on the variability of therapeutic efficacy observed in antidepressant treatment?"}
{"id": "001740", "text": "What psychosocial factors could increase the vulnerability of military personnel to depression?"}
{"id": "001742", "text": "How do working mothers avoid marginalization when giving their opinions in support groups?"}
{"id": "001743", "text": "How does the lack of research funding affect the development of new psychiatric treatments?"}
{"id": "001744", "text": "What are the benefits of improving mental health research?"}
{"id": "001747", "text": "What methods can be applied to reduce public stigma related to mental health?"}
{"id": "001748", "text": "What techniques can be used to improve a patient's aggressive behavior?"}
{"id": "001750", "text": "What are the economic implications of mental health issues?"}
{"id": "001751", "text": "Is talking about mental health issues actually helping?"}
{"id": "001752", "text": "What is lithium used for in medicine?"}
{"id": "001754", "text": "What are the limitations of current suicide prediction models?"}
{"id": "001755", "text": "Does the mother's lifestyle during pregnancy affect the risk of autism?"}
{"id": "001756", "text": "How can prolonged use of clozapine in a person with severe psychotic disorder trigger obsessive-compulsive disorder?"}
{"id": "001758", "text": "Does sensitivity to rejection play a role in a person's susceptibility to harassment?"}
{"id": "001760", "text": "What are the main obstacles faced by individuals with mental health issues?"}
{"id": "001761", "text": "How can technology improve the understanding of suicidal thoughts and behaviors?"}
{"id": "001762", "text": "How do societal expectations of mothers with mental illness influence their positioning and efforts to counter stereotypes of the \"bad mother\"?"}
{"id": "001763", "text": "By what neurobiological mechanisms does oxytocin secretion interact in the modulation of social anxiety symptoms and physical activity?"}
{"id": "001765", "text": "What does poor premorbid social adjustment mean?"}
{"id": "001766", "text": "What has been the trend in funding for mental health research?"}
{"id": "001767", "text": "What does a rights-based approach to health entail?"}
{"id": "001768", "text": "How does perceived social support mediate between the psychological state of individuals and their quality of life?"}
{"id": "001769", "text": "What challenges do suicide researchers face in predicting suicidal behaviors?"}
{"id": "001770", "text": "What is the significance of age at onset in the prognosis of schizophrenia?"}
{"id": "001771", "text": "What are ethical considerations when doing research on mental health conditions?"}
{"id": "001775", "text": "How do mothers with mental illness perceive and manage their maternal identity in the face of the fear of being labelled as \"bad mothers\"?"}
{"id": "001777", "text": "When it comes to predicting long-term needs for patients with dementia, what are the models' performance parameters?"}
{"id": "001778", "text": "Which is the genetic contribution to major depression risk?"}
{"id": "001779", "text": "What MoCA cut-off score distinguishes stroke patients who are cognitively impaired from those who are not?"}
{"id": "001781", "text": "Are DNA methylation changes linked with changes at the gene expression level?"}
{"id": "001782", "text": "How can the inclusion of testimonials from patients sharing identical psychological backgrounds potentially optimize the effectiveness and relevance of therapeutic responses?"}
{"id": "001783", "text": "Which anatomical parts of the brain can be exploited for a more specific treatment of a depressive syndrome?"}
{"id": "001785", "text": "How do researchers address potential biases in studies?"}
{"id": "001787", "text": "How does the principle of justice apply to mental health research?"}
{"id": "001788", "text": "What is the impact of voluntary disclosure of mental health problems on the quality of perceived social support and psychological well-being of palliative care professionals?"}
{"id": "001791", "text": "What underlying mechanisms link respect to positive psychotherapy outcomes?"}
{"id": "001792", "text": "What is the value of sharing the experience of patients with psychosis in the development of therapeutic protocols for this same illness?"}
{"id": "001793", "text": "What methodologies can be employed to assess genetic correlation?"}
{"id": "001794", "text": "Which are the new methods being used to understand suicidal behaviors?"}
{"id": "001796", "text": "Why can the MoCA test be more useful than other approaches for monitoring the cognitive status of stroke patients?"}
{"id": "001799", "text": "What are the benefits of participating in the HOP program?"}
{"id": "001800", "text": "What are the mechanisms that may explain the high mortality rate in men suffering from both mental disorders and social deprivation?"}
{"id": "001801", "text": "How does the automation of artificial intelligence methods play a key role in the clinical diagnosis of respiratory diseases?"}
{"id": "001802", "text": "What strategies are suggested to improve TB treatment access in Europe?"}
{"id": "001803", "text": "How does eosinophilic inflammation affect AT?"}
{"id": "001805", "text": "Which are the main factors associated with failure of CPAP therapy?"}
{"id": "001806", "text": "How did COVID-19 affect the fight against TB?"}
{"id": "001807", "text": "What is the role of the National Cancer Registry in India?"}
{"id": "001808", "text": "What has caused the decrease in TB treatments available in Europe?"}
{"id": "001810", "text": "What are the benefits of detecting remodeling associated with heart failure with normal ejection fraction?"}
{"id": "001813", "text": "What are the challenges regarding the '7-1-7' metric?"}
{"id": "001817", "text": "Can weight affect asthma?"}
{"id": "001818", "text": "Which arrhythmia can be treated more effectively by demonstrating the remodeling associated with heart failure with normal ejection fraction?"}
{"id": "001819", "text": "Which are the direct costs of a cost-of-illness study?"}
{"id": "001820", "text": "Is OSA related to motor vehicle accidents?"}
{"id": "001822", "text": "How do doctors measure air trapping in asthma patients?"}
{"id": "001824", "text": "What is the primary diagnostic criterion for heart failure with normal ejection fraction?"}
{"id": "001825", "text": "What aspects are thought to produce an increased risk of viral respiratory infections in athletes?"}
{"id": "001827", "text": "Could you name the main general HrQOL measures?"}
{"id": "001829", "text": "How has the understanding of COPD evolved in recent years?"}
{"id": "001832", "text": "What is the usual support that CPAP therapy models require?"}
{"id": "001833", "text": "Is respiratory failure still a risk for severely burned patients several days after admission, even after it has been ruled out in the first place?"}
{"id": "001836", "text": "What is the relation between ICER and QALY?"}
{"id": "001838", "text": "Is TB screening being conducted for all Ukrainian refugees?"}
{"id": "001839", "text": "How do changes in T cell expression, including a decrease in co-stimulatory molecules and an increase in regulatory T cells, influence the pathogenesis of non-tuberculous mycobacterial lung disease and response to treatment?"}
{"id": "001845", "text": "What is the recommended protocol for return-to-sport after a viral respiratory infection?"}
{"id": "001846", "text": "What are the current statistics on tuberculosis incidence in children?"}
{"id": "001848", "text": "What does it mean if someone can't walk 400 meters in six minutes?"}
{"id": "001849", "text": "Which are the main health consequences of Obstructive Sleep Apnea?"}
{"id": "001852", "text": "Which are the direct costs of OSA in the US?"}
{"id": "001854", "text": "Are private hospitals systematically included in cancer reports in India?"}
{"id": "001855", "text": "What initiatives have been launched to end TB in India?"}
{"id": "001856", "text": "To what extent can the reliability of lung sound analysis methods rule out biases caused by provocation tests, airway narrowing and airflow in asthma patients?"}
{"id": "001857", "text": "What is the indirect cost in a cost-of-illness study?"}
{"id": "001858", "text": "Are COVID-19 mitigation strategies successful in reducing transmission of the disease among athletes in major competitions?"}
{"id": "001859", "text": "Which are the main drivers of the high cost of OSA in the US?"}
{"id": "001860", "text": "Why is it so difficult to calculate OSA relate direct costs?"}
{"id": "001862", "text": "What improvements did the '7-1-7' metric bring to TB prevention?"}
{"id": "001866", "text": "Which are the main adverse consequences of OSAH?"}
{"id": "001867", "text": "What is the first line of treatment of OSA?"}
{"id": "001868", "text": "What are the differences in risk of immune-related lung disease between patients with lung cancer alone and those with concomitant COPD during immunotherapy?"}
{"id": "001873", "text": "What is the role of SORT IT?"}
{"id": "001874", "text": "What are the implications of persistent air trapping over time in asthma patients?"}
{"id": "001876", "text": "What is the pathogenesis of inhalation injury leading low levels of oxygen in the blood?"}
{"id": "001877", "text": "What are the challenges faced in referring TB patients for further care?"}
{"id": "001882", "text": "What is the rationale behind the air pressure treatment employed in OSAS?"}
{"id": "001883", "text": "Is there experimental evidence of the effect of abdominal muscle contraction on lung volume?"}
{"id": "001884", "text": "What are the risks associated with heart failure with normal ejection fraction?"}
{"id": "001885", "text": "What is the value of QALY as an economic metric?"}
{"id": "001887", "text": "What signifies vascular volume change in smokers?"}
{"id": "001888", "text": "What are the health risks of asbestos exposure?"}
{"id": "001889", "text": "What is the testing recommendation for athletes suffering cardiopulmonary symptoms?"}
{"id": "001892", "text": "What is the '7-1-7' metric in TB contact tracing?"}
{"id": "001893", "text": "Are there any methods that can help doctors through TB assessment, triage, and referrals?"}
{"id": "001895", "text": "Are OSA treatments cost-effective?"}
{"id": "001897", "text": "Why do some countries have higher rates of TB testing compared to others?"}
{"id": "001899", "text": "What is the ICER when speaking about costs of health resources?"}
{"id": "001901", "text": "What methodologies were used to create the AT scoring system?"}
{"id": "001902", "text": "What role can international authorities play in ending TB?"}
{"id": "001903", "text": "What are the current gaps in our understanding of COPD?"}
{"id": "001904", "text": "What remodeling abnormalities are found in heart failure with normal ejection fraction?"}
{"id": "001905", "text": "What other diagnostic criteria appear later in heart failure with normal ejection fraction?"}
{"id": "001906", "text": "Is asbestos still used in India?"}
{"id": "001907", "text": "What are the signs of accelerated lung function decline?"}
{"id": "001908", "text": "How could the integration of TB care with universal health coverage (UHC) work?"}
{"id": "001912", "text": "What are the flaws of CT measurements of air trapping?"}
{"id": "001916", "text": "Is home sleep apnea testing a valuable option for OSA screening?"}
{"id": "001918", "text": "Why is it important to have accurate records of mesothelioma cases?"}
{"id": "001920", "text": "Is the adherence to the CPAP as treatment of OSA related to the cost of OSA?"}
{"id": "001921", "text": "How has the COVID-19 pandemic impacted TB diagnosis and treatment?"}
{"id": "001922", "text": "What advancements have been made in the treatment of COPD?"}
{"id": "001926", "text": "Is any level of asbestos exposure considered harmless?"}
{"id": "001929", "text": "What are the specific mechanisms by which chronic obstructive pulmonary disease influences the risk of immune-related lung disease in patients treated with immune checkpoint inhibitors?"}
{"id": "001934", "text": "Why is it important to screen household contacts of TB patients?"}
{"id": "001935", "text": "What does literature say about the risk of ARDS  in burn patients with damage to the respiratory system caused by the aspiration of harmful gases?"}
{"id": "001936", "text": "What did the latest studies reveal about asbestos exposure in India?"}
{"id": "001937", "text": "What is the main factor for accelerated loss of lung function for smokers?"}
{"id": "001938", "text": "How has the COVID-19 pandemic affected tuberculosis care for children?"}
{"id": "001939", "text": "What are the consequences of not having a representative overview of mesothelioma cases?"}
{"id": "001941", "text": "What challenges are associated with the current cancer registry system in India?"}
{"id": "001945", "text": "What improvements are needed in the care of TB patients?"}
{"id": "001946", "text": "Which are the main race-related and socioeconomic-related determinants of OSA and OSA outcomes?"}
{"id": "001947", "text": "Can air trapping in asthma be modified with treatment?"}
{"id": "001948", "text": "Knowing that access to cardiovascular magnetic resonance is limited, are there other tests that can contribute to the diagnosis of heart failure with normal ejection fraction?"}
{"id": "001950", "text": "Should the athlete that is suspected of suffering a respiratory infection be tested for viral or bacterial etiology?"}
{"id": "001958", "text": "What is air trapping in asthma?"}
{"id": "001961", "text": "How many people are affected by mesothelioma in India?"}
{"id": "001962", "text": "What is used to identify predictive factors for COPD?"}
{"id": "001965", "text": "What challenges do medical personnel face when implementing TB preventive therapy?"}
{"id": "001966", "text": "How effective was the '7-1-7' metric compared to previous methods?"}
{"id": "001967", "text": "What are the primary uses of asbestos in India?"}
{"id": "001969", "text": "What are the implications of COPD for current public health strategies and preventive measures?"}
{"id": "001970", "text": "Why is it important to study lung function from a young age?"}
{"id": "001971", "text": "How does the Right to Information Act help in gathering data for medical research?"}
{"id": "001972", "text": "What are the main reasons household contacts might refuse TB preventive therapy?"}
{"id": "001973", "text": "Are respiratory symptoms linked with the progression of lung diseases?"}
{"id": "001976", "text": "What are the disadvantages of externalizing health services?"}
{"id": "001977", "text": "What has been the trend in TB occurrence in Europe since 2012?"}
{"id": "001979", "text": "What were the main findings regarding TB rates among Ukrainian refugees?"}
{"id": "001981", "text": "What is the purpose of assessing TB patients for other health issues?"}
{"id": "001983", "text": "Is it possible to reduce air trapping in asthma?"}
{"id": "001985", "text": "Is there a test to certify the damage to the respiratory system caused by the aspiration of harmful gases?"}
{"id": "001986", "text": "How effective is the '7-1-7' method for tuberculosis screening?"}
{"id": "001988", "text": "How does testing affect the reported rates of TB?"}
{"id": "001989", "text": "Can air trapping in asthma change over time?"}
{"id": "001990", "text": "How can community monitoring help in the fight against TB?"}
{"id": "001991", "text": "How does the '7-1-7' metric compare to previous TB prevention strategies?"}
{"id": "001993", "text": "What is the significance of lung function trajectories in understanding respiratory diseases?"}
{"id": "001996", "text": "What are the obstacles in combating TB today?"}
{"id": "001997", "text": "What are the goals for TB treatment and prevention by the UN?"}
{"id": "001998", "text": "What are the suggested strategies for enhancing TB monitoring among refugees?"}
{"id": "002000", "text": "What is the actual trend of OSA in the world?"}