Daily Papers

Foundation models for interactive segmentation in 2D natural images and videos have sparked significant interest in building 3D foundation models for medical imaging. However, the domain gaps and clinical use cases for 3D medical imaging require a dedicated model that diverges from existing 2D solutions. Specifically, such foundation models should support a full workflow that can actually reduce human effort. Treating 3D medical images as sequences of 2D slices and reusing interactive 2D foundation models seems straightforward, but 2D annotation is too time-consuming for 3D tasks. Moreover, for large cohort analysis, it's the highly accurate automatic segmentation models that reduce the most human effort. However, these models lack support for interactive corrections and lack zero-shot ability for novel structures, which is a key feature of "foundation". While reusing pre-trained 2D backbones in 3D enhances zero-shot potential, their performance on complex 3D structures still lags behind leading 3D models. To address these issues, we present VISTA3D, Versatile Imaging SegmenTation and Annotation model, that targets to solve all these challenges and requirements with one unified foundation model. VISTA3D is built on top of the well-established 3D segmentation pipeline, and it is the first model to achieve state-of-the-art performance in both 3D automatic (supporting 127 classes) and 3D interactive segmentation, even when compared with top 3D expert models on large and diverse benchmarks. Additionally, VISTA3D's 3D interactive design allows efficient human correction, and a novel 3D supervoxel method that distills 2D pretrained backbones grants VISTA3D top 3D zero-shot performance. We believe the model, recipe, and insights represent a promising step towards a clinically useful 3D foundation model. Code and weights are publicly available at https://github.com/Project-MONAI/VISTA.

Segmenting 3D blood vessels is a critical yet challenging task in medical image analysis. This is due to significant imaging modality-specific variations in artifacts, vascular patterns and scales, signal-to-noise ratios, and background tissues. These variations, along with domain gaps arising from varying imaging protocols, limit the generalization of existing supervised learning-based methods, requiring tedious voxel-level annotations for each dataset separately. While foundation models promise to alleviate this limitation, they typically fail to generalize to the task of blood vessel segmentation, posing a unique, complex problem. In this work, we present vesselFM, a foundation model designed specifically for the broad task of 3D blood vessel segmentation. Unlike previous models, vesselFM can effortlessly generalize to unseen domains. To achieve zero-shot generalization, we train vesselFM on three heterogeneous data sources: a large, curated annotated dataset, data generated by a domain randomization scheme, and data sampled from a flow matching-based generative model. Extensive evaluations show that vesselFM outperforms state-of-the-art medical image segmentation foundation models across four (pre-)clinically relevant imaging modalities in zero-, one-, and few-shot scenarios, therefore providing a universal solution for 3D blood vessel segmentation.

Current 3D scene segmentation methods are heavily dependent on manually annotated 3D training datasets. Such manual annotations are labor-intensive, and often lack fine-grained details. Importantly, models trained on this data typically struggle to recognize object classes beyond the annotated classes, i.e., they do not generalize well to unseen domains and require additional domain-specific annotations. In contrast, 2D foundation models demonstrate strong generalization and impressive zero-shot abilities, inspiring us to incorporate these characteristics from 2D models into 3D models. Therefore, we explore the use of image segmentation foundation models to automatically generate training labels for 3D segmentation. We propose Segment3D, a method for class-agnostic 3D scene segmentation that produces high-quality 3D segmentation masks. It improves over existing 3D segmentation models (especially on fine-grained masks), and enables easily adding new training data to further boost the segmentation performance -- all without the need for manual training labels.

Heatwaves pose significant health risks, particularly due to prolonged exposure to high summer temperatures. Vulnerable groups, especially pedestrians and cyclists on sun-exposed sidewalks, motivate the development of a route planning method that incorporates somatosensory temperature effects through shade ratio consideration. This paper is the first to introduce a pipeline that utilizes segmentation foundation models to extract shaded areas from high-resolution satellite images. These areas are then integrated into a multi-layered road map, enabling users to customize routes based on a balance between distance and shade exposure, thereby enhancing comfort and health during outdoor activities. Specifically, we construct a graph-based representation of the road map, where links indicate connectivity and are updated with shade ratio data for dynamic route planning. This system is already implemented online, with a video demonstration, and will be specifically adapted to assist travelers during the 2024 Olympic Games in Paris.

Open-set 3D segmentation represents a major point of interest for multiple downstream robotics and augmented/virtual reality applications. We present a decoupled 3D segmentation pipeline to ensure modularity and adaptability to novel 3D representations as well as semantic segmentation foundation models. We first reconstruct a scene with 3D Gaussians and learn class-agnostic features through contrastive supervision from a 2D instance proposal network. These 3D features are then clustered to form coarse object- or part-level masks. Finally, we match each 3D cluster to class-aware masks predicted by a 2D open-vocabulary segmentation model, assigning semantic labels without retraining the 3D representation. Our decoupled design (1) provides a plug-and-play interface for swapping different 2D or 3D modules, (2) ensures multi-object instance segmentation at no extra cost, and (3) leverages rich 3D geometry for robust scene understanding. We evaluate on synthetic and real-world indoor datasets, demonstrating improved performance over comparable NeRF-based pipelines on mIoU and mAcc, particularly for challenging or long-tail classes. We also show how varying the 2D backbone affects the final segmentation, highlighting the modularity of our framework. These results confirm that decoupling 3D mask proposal and semantic classification can deliver flexible, efficient, and open-vocabulary 3D segmentation.

Recent advances in segmentation foundation models have enabled accurate and efficient segmentation across a wide range of natural images and videos, but their utility to medical data remains unclear. In this work, we first present a comprehensive benchmarking of the Segment Anything Model 2 (SAM2) across 11 medical image modalities and videos and point out its strengths and weaknesses by comparing it to SAM1 and MedSAM. Then, we develop a transfer learning pipeline and demonstrate SAM2 can be quickly adapted to medical domain by fine-tuning. Furthermore, we implement SAM2 as a 3D slicer plugin and Gradio API for efficient 3D image and video segmentation. The code has been made publicly available at https://github.com/bowang-lab/MedSAM.

Foundation models, pre-trained on a large amount of data have demonstrated impressive zero-shot capabilities in various downstream tasks. However, in object detection and instance segmentation, two fundamental computer vision tasks heavily reliant on extensive human annotations, foundation models such as SAM and DINO struggle to achieve satisfactory performance. In this study, we reveal that the devil is in the object boundary, i.e., these foundation models fail to discern boundaries between individual objects. For the first time, we probe that CLIP, which has never accessed any instance-level annotations, can provide a highly beneficial and strong instance-level boundary prior in the clustering results of its particular intermediate layer. Following this surprising observation, we propose Zip which Zips up CLip and SAM in a novel classification-first-then-discovery pipeline, enabling annotation-free, complex-scene-capable, open-vocabulary object detection and instance segmentation. Our Zip significantly boosts SAM's mask AP on COCO dataset by 12.5% and establishes state-of-the-art performance in various settings, including training-free, self-training, and label-efficient finetuning. Furthermore, annotation-free Zip even achieves comparable performance to the best-performing open-vocabulary object detecters using base annotations. Code is released at https://github.com/ChengShiest/Zip-Your-CLIP

Segmenting and recognizing diverse object parts is crucial in computer vision and robotics. Despite significant progress in object segmentation, part-level segmentation remains underexplored due to complex boundaries and scarce annotated data. To address this, we propose a novel Weakly-supervised Part Segmentation (WPS) setting and an approach called WPS-SAM, built on the large-scale pre-trained vision foundation model, Segment Anything Model (SAM). WPS-SAM is an end-to-end framework designed to extract prompt tokens directly from images and perform pixel-level segmentation of part regions. During its training phase, it only uses weakly supervised labels in the form of bounding boxes or points. Extensive experiments demonstrate that, through exploiting the rich knowledge embedded in pre-trained foundation models, WPS-SAM outperforms other segmentation models trained with pixel-level strong annotations. Specifically, WPS-SAM achieves 68.93% mIOU and 79.53% mACC on the PartImageNet dataset, surpassing state-of-the-art fully supervised methods by approximately 4% in terms of mIOU.

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level segmentation annotations on the large-scale pretraining dataset, pretraining with unannotated images is highly desirable. In this work, we propose a novel self-supervised learning strategy named Volume Fusion (VF) for pretraining 3D segmentation models. It fuses several random patches from a foreground sub-volume to a background sub-volume based on a predefined set of discrete fusion coefficients, and forces the model to predict the fusion coefficient of each voxel, which is formulated as a self-supervised segmentation task without manual annotations. Additionally, we propose a novel network architecture based on parallel convolution and transformer blocks that is suitable to be transferred to different downstream segmentation tasks with various scales of organs and lesions. The proposed model was pretrained with 110k unannotated 3D CT volumes, and experiments with different downstream segmentation targets including head and neck organs, thoracic/abdominal organs showed that our pretrained model largely outperformed training from scratch and several state-of-the-art self-supervised training methods and segmentation models. The code and pretrained model are available at https://github.com/openmedlab/MIS-FM.

Referring Remote Sensing Image Segmentation provides a flexible and fine-grained framework for remote sensing scene analysis via vision-language collaborative interpretation. Current approaches predominantly utilize a three-stage pipeline encompassing dual-modal encoding, cross-modal interaction, and pixel decoding. These methods demonstrate significant limitations in managing complex semantic relationships and achieving precise cross-modal alignment, largely due to their coupled processing mechanism that conflates target localization with boundary delineation. This architectural coupling amplifies error propagation under semantic ambiguity while restricting model generalizability and interpretability. To address these issues, we propose RSRefSeg 2, a decoupling paradigm that reformulates the conventional workflow into a collaborative dual-stage framework: coarse localization followed by fine segmentation. RSRefSeg 2 integrates CLIP's cross-modal alignment strength with SAM's segmentation generalizability through strategic foundation model collaboration. Specifically, CLIP is employed as the dual-modal encoder to activate target features within its pre-aligned semantic space and generate localization prompts. To mitigate CLIP's misactivation challenges in multi-entity scenarios described by referring texts, a cascaded second-order prompter is devised, which enhances precision through implicit reasoning via decomposition of text embeddings into complementary semantic subspaces. These optimized semantic prompts subsequently direct the SAM to generate pixel-level refined masks, thereby completing the semantic transmission pipeline. Extensive experiments (RefSegRS, RRSIS-D, and RISBench) demonstrate that RSRefSeg 2 surpasses contemporary methods in segmentation accuracy (+~3% gIoU) and complex semantic interpretation. Code is available at: https://github.com/KyanChen/RSRefSeg2.

Foundation segmentation models, while powerful, pose a significant risk: they enable users to effortlessly extract any objects from any digital content with a single click, potentially leading to copyright infringement or malicious misuse. To mitigate this risk, we introduce a new task "Anything Unsegmentable" to grant any image "the right to be unsegmented". The ambitious pursuit of the task is to achieve highly transferable adversarial attacks against all prompt-based segmentation models, regardless of model parameterizations and prompts. We highlight the non-transferable and heterogeneous nature of prompt-specific adversarial noises. Our approach focuses on disrupting image encoder features to achieve prompt-agnostic attacks. Intriguingly, targeted feature attacks exhibit better transferability compared to untargeted ones, suggesting the optimal update direction aligns with the image manifold. Based on the observations, we design a novel attack named Unsegment Anything by Simulating Deformation (UAD). Our attack optimizes a differentiable deformation function to create a target deformed image, which alters structural information while preserving achievable feature distance by adversarial example. Extensive experiments verify the effectiveness of our approach, compromising a variety of promptable segmentation models with different architectures and prompt interfaces. We release the code at https://github.com/jiahaolu97/anything-unsegmentable.

In this paper, we address the challenge of decomposing Neural Radiance Fields (NeRF) into objects from an open vocabulary, a critical task for object manipulation in 3D reconstruction and view synthesis. Current techniques for NeRF decomposition involve a trade-off between the flexibility of processing open-vocabulary queries and the accuracy of 3D segmentation. We present, Open-vocabulary Embedded Neural Radiance Fields (Open-NeRF), that leverage large-scale, off-the-shelf, segmentation models like the Segment Anything Model (SAM) and introduce an integrate-and-distill paradigm with hierarchical embeddings to achieve both the flexibility of open-vocabulary querying and 3D segmentation accuracy. Open-NeRF first utilizes large-scale foundation models to generate hierarchical 2D mask proposals from varying viewpoints. These proposals are then aligned via tracking approaches and integrated within the 3D space and subsequently distilled into the 3D field. This process ensures consistent recognition and granularity of objects from different viewpoints, even in challenging scenarios involving occlusion and indistinct features. Our experimental results show that the proposed Open-NeRF outperforms state-of-the-art methods such as LERF lerf and FFD ffd in open-vocabulary scenarios. Open-NeRF offers a promising solution to NeRF decomposition, guided by open-vocabulary queries, enabling novel applications in robotics and vision-language interaction in open-world 3D scenes.

Cloud segmentation is a critical challenge in remote sensing image interpretation, as its accuracy directly impacts the effectiveness of subsequent data processing and analysis. Recently, vision foundation models (VFM) have demonstrated powerful generalization capabilities across various visual tasks. In this paper, we present a parameter-efficient adaptive approach, termed Cloud-Adapter, designed to enhance the accuracy and robustness of cloud segmentation. Our method leverages a VFM pretrained on general domain data, which remains frozen, eliminating the need for additional training. Cloud-Adapter incorporates a lightweight spatial perception module that initially utilizes a convolutional neural network (ConvNet) to extract dense spatial representations. These multi-scale features are then aggregated and serve as contextual inputs to an adapting module, which modulates the frozen transformer layers within the VFM. Experimental results demonstrate that the Cloud-Adapter approach, utilizing only 0.6% of the trainable parameters of the frozen backbone, achieves substantial performance gains. Cloud-Adapter consistently attains state-of-the-art (SOTA) performance across a wide variety of cloud segmentation datasets from multiple satellite sources, sensor series, data processing levels, land cover scenarios, and annotation granularities. We have released the source code and pretrained models at https://github.com/XavierJiezou/Cloud-Adapter to support further research.

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models or adapting them to a new condition is costly due to the need for (manually) labeled data. The emergence of vision foundation models, especially Segment Anything, offers a path to universal segmentation for medical images, overcoming these issues. Here, we study how to improve Segment Anything for medical images by comparing different finetuning strategies on a large and diverse dataset. We evaluate the finetuned models on a wide range of interactive and (automatic) semantic segmentation tasks. We find that the performance can be clearly improved for interactive segmentation. However, semantic segmentation does not benefit from pretraining on medical images. Our best model, MedicoSAM, is publicly available at https://github.com/computational-cell-analytics/medico-sam. We show that it is compatible with existing tools for data annotation and believe that it will be of great practical value.

Zero-shot and prompt-based technologies capitalized on using frequently occurring images to transform visual reasoning tasks, which explains why such technologies struggle with valuable yet scarce scientific image sets. In this work, we propose Zenesis, a comprehensive no-code interactive platform designed to minimize barriers posed by data readiness for scientific images. We develop lightweight multi-modal adaptation techniques that enable zero-shot operation on raw scientific data, along with human-in-the-loop refinement and heuristic-based temporal enhancement options. We demonstrate the performance of our approach through comprehensive comparison and validation on challenging Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) data of catalyst-loaded membranes. Zenesis significantly outperforms baseline methods, achieving an average accuracy of 0.947, an Intersection over Union (IOU) of 0.858, and a Dice score of 0.923 for amorphous catalyst samples and accuracy of 0.987, an IOU of 0.857, and a Dice score of 0.923 for crystalline samples. These results mark a substantial improvement over traditional methods like Otsu thresholding and even advanced models like Segment Anything Model (SAM) when used in isolation. Our results demonstrate that Zenesis is a powerful tool for scientific applications, particularly in fields where high-quality annotated datasets are unavailable, accelerating accurate analysis of experimental imaging.

While Contrastive Language-Image Pre-training (CLIP) has advanced open-vocabulary predictions, its performance on semantic segmentation remains suboptimal. This shortfall primarily stems from its spatial-invariant semantic features and constrained resolution. While previous adaptations addressed spatial invariance semantic by modifying the self-attention in CLIP's image encoder, the issue of limited resolution remains unexplored. Different from previous segment-then-splice methods that segment sub-images via a sliding window and splice the results, we introduce a splice-then-segment paradigm that incorporates Segment-Anything Model (SAM) to tackle the resolution issue since SAM excels at extracting fine-grained semantic correlations from high-resolution images. Specifically, we introduce Trident, a training-free framework that first splices features extracted by CLIP and DINO from sub-images, then leverages SAM's encoder to create a correlation matrix for global aggregation, enabling a broadened receptive field for effective segmentation. Besides, we propose a refinement strategy for CLIP's coarse segmentation outputs by transforming them into prompts for SAM, further enhancing the segmentation performance. Trident achieves a significant improvement in the mIoU across eight benchmarks compared with the current SOTA, increasing from 44.4 to 48.6.Code is available at https://github.com/YuHengsss/Trident.

The study of Maya hieroglyphic writing unlocks the rich history of cultural and societal knowledge embedded within this ancient civilization's visual narrative. Artificial Intelligence (AI) offers a novel lens through which we can translate these inscriptions, with the potential to allow non-specialists access to reading these texts and to aid in the decipherment of those hieroglyphs which continue to elude comprehensive interpretation. Toward this, we leverage a foundational model to segment Maya hieroglyphs from an open-source digital library dedicated to Maya artifacts. Despite the initial promise of publicly available foundational segmentation models, their effectiveness in accurately segmenting Maya hieroglyphs was initially limited. Addressing this challenge, our study involved the meticulous curation of image and label pairs with the assistance of experts in Maya art and history, enabling the fine-tuning of these foundational models. This process significantly enhanced model performance, illustrating the potential of fine-tuning approaches and the value of our expanding dataset. We plan to open-source this dataset for encouraging future research, and eventually to help make the hieroglyphic texts legible to a broader community, particularly for Maya heritage community members.

Open-vocabulary segmentation poses significant challenges, as it requires segmenting and recognizing objects across an open set of categories in unconstrained environments. Building on the success of powerful vision-language (ViL) foundation models, such as CLIP, recent efforts sought to harness their zero-short capabilities to recognize unseen categories. Despite notable performance improvements, these models still encounter the critical issue of generating precise mask proposals for unseen categories and scenarios, resulting in inferior segmentation performance eventually. To address this challenge, we introduce a novel approach, FrozenSeg, designed to integrate spatial knowledge from a localization foundation model (e.g., SAM) and semantic knowledge extracted from a ViL model (e.g., CLIP), in a synergistic framework. Taking the ViL model's visual encoder as the feature backbone, we inject the space-aware feature into the learnable queries and CLIP features within the transformer decoder. In addition, we devise a mask proposal ensemble strategy for further improving the recall rate and mask quality. To fully exploit pre-trained knowledge while minimizing training overhead, we freeze both foundation models, focusing optimization efforts solely on a lightweight transformer decoder for mask proposal generation-the performance bottleneck. Extensive experiments demonstrate that FrozenSeg advances state-of-the-art results across various segmentation benchmarks, trained exclusively on COCO panoptic data, and tested in a zero-shot manner. Code is available at https://github.com/chenxi52/FrozenSeg.

Vision Foundation Models (VFMs) and Vision-Language Models (VLMs) have gained traction in Domain Generalized Semantic Segmentation (DGSS) due to their strong generalization capabilities. However, existing DGSS methods often rely exclusively on either VFMs or VLMs, overlooking their complementary strengths. VFMs (e.g., DINOv2) excel at capturing fine-grained features, while VLMs (e.g., CLIP) provide robust text alignment but struggle with coarse granularity. Despite their complementary strengths, effectively integrating VFMs and VLMs with attention mechanisms is challenging, as the increased patch tokens complicate long-sequence modeling. To address this, we propose MFuser, a novel Mamba-based fusion framework that efficiently combines the strengths of VFMs and VLMs while maintaining linear scalability in sequence length. MFuser consists of two key components: MVFuser, which acts as a co-adapter to jointly fine-tune the two models by capturing both sequential and spatial dynamics; and MTEnhancer, a hybrid attention-Mamba module that refines text embeddings by incorporating image priors. Our approach achieves precise feature locality and strong text alignment without incurring significant computational overhead. Extensive experiments demonstrate that MFuser significantly outperforms state-of-the-art DGSS methods, achieving 68.20 mIoU on synthetic-to-real and 71.87 mIoU on real-to-real benchmarks. The code is available at https://github.com/devinxzhang/MFuser.

Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in pathology image analysis. However, their improvements in cell instance segmentation remain limited. A key challenge arises from the tokenization process in ViTs, which substantially reduces the spatial resolution of input images, leading to suboptimal segmentation quality, especially for small and densely packed cells. To address this problem, we propose CellVTA (Cell Vision Transformer with Adapter), a novel method that improves the performance of vision foundation models for cell instance segmentation by incorporating a CNN-based adapter module. This adapter extracts high-resolution spatial information from input images and injects it into the ViT through a cross-attention mechanism. Our method preserves the core architecture of ViT, ensuring seamless integration with pretrained foundation models. Extensive experiments show that CellVTA achieves 0.538 mPQ on the CoNIC dataset and 0.506 mPQ on the PanNuke dataset, which significantly outperforms the state-of-the-art cell segmentation methods. Ablation studies confirm the superiority of our approach over other fine-tuning strategies, including decoder-only fine-tuning and full fine-tuning. Our code and models are publicly available at https://github.com/JieZheng-ShanghaiTech/CellVTA.

The realm of computer vision has witnessed a paradigm shift with the advent of foundational models, mirroring the transformative influence of large language models in the domain of natural language processing. This paper delves into the exploration of open-world segmentation, presenting a novel approach called Image Prompt Segmentation (IPSeg) that harnesses the power of vision foundational models. IPSeg lies the principle of a training-free paradigm, which capitalizes on image prompt techniques. Specifically, IPSeg utilizes a single image containing a subjective visual concept as a flexible prompt to query vision foundation models like DINOv2 and Stable Diffusion. Our approach extracts robust features for the prompt image and input image, then matches the input representations to the prompt representations via a novel feature interaction module to generate point prompts highlighting target objects in the input image. The generated point prompts are further utilized to guide the Segment Anything Model to segment the target object in the input image. The proposed method stands out by eliminating the need for exhaustive training sessions, thereby offering a more efficient and scalable solution. Experiments on COCO, PASCAL VOC, and other datasets demonstrate IPSeg's efficacy for flexible open-world segmentation using intuitive image prompts. This work pioneers tapping foundation models for open-world understanding through visual concepts conveyed in images.

In this paper, we first assess and harness various Vision Foundation Models (VFMs) in the context of Domain Generalized Semantic Segmentation (DGSS). Driven by the motivation that Leveraging Stronger pre-trained models and Fewer trainable parameters for Superior generalizability, we introduce a robust fine-tuning approach, namely Rein, to parameter-efficiently harness VFMs for DGSS. Built upon a set of trainable tokens, each linked to distinct instances, Rein precisely refines and forwards the feature maps from each layer to the next layer within the backbone. This process produces diverse refinements for different categories within a single image. With fewer trainable parameters, Rein efficiently fine-tunes VFMs for DGSS tasks, surprisingly surpassing full parameter fine-tuning. Extensive experiments across various settings demonstrate that Rein significantly outperforms state-of-the-art methods. Remarkably, with just an extra 1% of trainable parameters within the frozen backbone, Rein achieves a mIoU of 78.4% on the Cityscapes, without accessing any real urban-scene datasets.Code is available at https://github.com/w1oves/Rein.git.

We present FIND, a generalized interface for aligning foundation models' embeddings. As shown in teaser figure, a lightweight transformer interface without tuning any foundation model weights is enough for a unified image (segmentation) and dataset-level (retrieval) understanding. The proposed interface has the following favorable attributes: (1) Generalizable. It applies to various tasks spanning retrieval, segmentation, etc., under the same architecture and weights. (2) Prototypable. Different tasks are able to be implemented through prototyping attention masks and embedding types. (3) Extendable. The proposed interface is adaptive to new tasks, and new models. (4) Interleavable. With the benefit of multi-task multi-modal training, the proposed interface creates an interleaved shared embedding space. In light of the interleaved embedding space, we introduce the FIND-Bench, which introduces new training and evaluation annotations to the COCO dataset for interleave segmentation and retrieval. Our approach achieves state-of-the-art performance on FIND-Bench and competitive performance on standard retrieval and segmentation settings. The training, evaluation, and demo code as well as the dataset have been released at https://github.com/UX-Decoder/FIND.

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for various radiological tasks. CT-FM was pre-trained using 148,000 computed tomography (CT) scans from the Imaging Data Commons through label-agnostic contrastive learning. We evaluated CT-FM across four categories of tasks, namely, whole-body and tumor segmentation, head CT triage, medical image retrieval, and semantic understanding, showing superior performance against state-of-the-art models. Beyond quantitative success, CT-FM demonstrated the ability to cluster regions anatomically and identify similar anatomical and structural concepts across scans. Furthermore, it remained robust across test-retest settings and indicated reasonable salient regions attached to its embeddings. This study demonstrates the value of large-scale medical imaging foundation models and by open-sourcing the model weights, code, and data, aims to support more adaptable, reliable, and interpretable AI solutions in radiology.

The integration of deep learning systems into the medical domain has been hindered by the resource-intensive process of data annotation and the inability of these systems to generalize to different data distributions. Foundation models, which are models pre-trained on large datasets, have emerged as a solution to reduce reliance on annotated data and enhance model generalizability and robustness. DINOv2, an open-source foundation model pre-trained with self-supervised learning on 142 million curated natural images, excels in extracting general-purpose visual representations, exhibiting promising capabilities across various vision tasks. Nevertheless, a critical question remains unanswered regarding DINOv2's adaptability to radiological imaging, and the clarity on whether its features are sufficiently general to benefit radiology image analysis is yet to be established. Therefore, this study comprehensively evaluates DINOv2 for radiology, conducting over 100 experiments across diverse modalities (X-ray, CT, and MRI). Tasks include disease classification and organ segmentation on both 2D and 3D images, evaluated under different settings like kNN, few-shot learning, linear-probing, end-to-end fine-tuning, and parameter-efficient fine-tuning, to measure the effectiveness and generalizability of the DINOv2 feature embeddings. Comparative analyses with established medical image analysis models, U-Net and TransUnet for segmentation, and CNN and ViT models pre-trained via supervised, weakly supervised, and self-supervised learning for classification, reveal DINOv2's superior performance in segmentation tasks and competitive results in disease classification. The findings contribute insights to potential avenues for optimizing pre-training strategies for medical imaging and enhancing the broader understanding of DINOv2's role in bridging the gap between natural and radiological image analysis.

Audio-visual segmentation aims to separate sounding objects from videos by predicting pixel-level masks based on audio signals. Existing methods primarily concentrate on closed-set scenarios and direct audio-visual alignment and fusion, which limits their capability to generalize to new, unseen situations. In this paper, we propose OpenAVS, a novel training-free language-based approach that, for the first time, effectively aligns audio and visual modalities using text as a proxy for open-vocabulary Audio-Visual Segmentation (AVS). Equipped with multimedia foundation models, OpenAVS directly infers masks through 1) audio-to-text prompt generation, 2) LLM-guided prompt translation, and 3) text-to-visual sounding object segmentation. The objective of OpenAVS is to establish a simple yet flexible architecture that relies on the most appropriate foundation models by fully leveraging their capabilities to enable more effective knowledge transfer to the downstream AVS task. Moreover, we present a model-agnostic framework OpenAVS-ST that enables the integration of OpenAVS with any advanced supervised AVS model via pseudo-label based self-training. This approach enhances performance by effectively utilizing large-scale unlabeled data when available. Comprehensive experiments on three benchmark datasets demonstrate the superior performance of OpenAVS. It surpasses existing unsupervised, zero-shot, and few-shot AVS methods by a significant margin, achieving absolute performance gains of approximately 9.4% and 10.9% in mIoU and F-score, respectively, in challenging scenarios.

Very-High Resolution (VHR) remote sensing imagery is increasingly accessible, but often lacks annotations for effective machine learning applications. Recent foundation models like GroundingDINO and Segment Anything (SAM) provide opportunities to automatically generate annotations. This study introduces FMARS (Foundation Model Annotations in Remote Sensing), a methodology leveraging VHR imagery and foundation models for fast and robust annotation. We focus on disaster management and provide a large-scale dataset with labels obtained from pre-event imagery over 19 disaster events, derived from the Maxar Open Data initiative. We train segmentation models on the generated labels, using Unsupervised Domain Adaptation (UDA) techniques to increase transferability to real-world scenarios. Our results demonstrate the effectiveness of leveraging foundation models to automatically annotate remote sensing data at scale, enabling robust downstream models for critical applications. Code and dataset are available at https://github.com/links-ads/igarss-fmars.

Significant progress in the development of highly adaptable and reusable Artificial Intelligence (AI) models is expected to have a significant impact on Earth science and remote sensing. Foundation models are pre-trained on large unlabeled datasets through self-supervision, and then fine-tuned for various downstream tasks with small labeled datasets. This paper introduces a first-of-a-kind framework for the efficient pre-training and fine-tuning of foundational models on extensive geospatial data. We have utilized this framework to create Prithvi, a transformer-based geospatial foundational model pre-trained on more than 1TB of multispectral satellite imagery from the Harmonized Landsat-Sentinel 2 (HLS) dataset. Our study demonstrates the efficacy of our framework in successfully fine-tuning Prithvi to a range of Earth observation tasks that have not been tackled by previous work on foundation models involving multi-temporal cloud gap imputation, flood mapping, wildfire scar segmentation, and multi-temporal crop segmentation. Our experiments show that the pre-trained model accelerates the fine-tuning process compared to leveraging randomly initialized weights. In addition, pre-trained Prithvi compares well against the state-of-the-art, e.g., outperforming a conditional GAN model in multi-temporal cloud imputation by up to 5pp (or 5.7%) in the structural similarity index. Finally, due to the limited availability of labeled data in the field of Earth observation, we gradually reduce the quantity of available labeled data for refining the model to evaluate data efficiency and demonstrate that data can be decreased significantly without affecting the model's accuracy. The pre-trained 100 million parameter model and corresponding fine-tuning workflows have been released publicly as open source contributions to the global Earth sciences community through Hugging Face.

Clinical decision-making routinely demands reasoning over heterogeneous data, yet existing multimodal language models (MLLMs) remain largely vision-centric and fail to generalize across clinical specialties. To bridge this gap, we introduce QoQ-Med-7B/32B, the first open generalist clinical foundation model that jointly reasons across medical images, time-series signals, and text reports. QoQ-Med is trained with Domain-aware Relative Policy Optimization (DRPO), a novel reinforcement-learning objective that hierarchically scales normalized rewards according to domain rarity and modality difficulty, mitigating performance imbalance caused by skewed clinical data distributions. Trained on 2.61 million instruction tuning pairs spanning 9 clinical domains, we show that DRPO training boosts diagnostic performance by 43% in macro-F1 on average across all visual domains as compared to other critic-free training methods like GRPO. Furthermore, with QoQ-Med trained on intensive segmentation data, it is able to highlight salient regions related to the diagnosis, with an IoU 10x higher than open models while reaching the performance of OpenAI o4-mini. To foster reproducibility and downstream research, we release (i) the full model weights, (ii) the modular training pipeline, and (iii) all intermediate reasoning traces at https://github.com/DDVD233/QoQ_Med.

Curating datasets for object segmentation is a difficult task. With the advent of large-scale pre-trained generative models, conditional image generation has been given a significant boost in result quality and ease of use. In this paper, we present a novel method that enables the generation of general foreground-background segmentation models from simple textual descriptions, without requiring segmentation labels. We leverage and explore pre-trained latent diffusion models, to automatically generate weak segmentation masks for concepts and objects. The masks are then used to fine-tune the diffusion model on an inpainting task, which enables fine-grained removal of the object, while at the same time providing a synthetic foreground and background dataset. We demonstrate that using this method beats previous methods in both discriminative and generative performance and closes the gap with fully supervised training while requiring no pixel-wise object labels. We show results on the task of segmenting four different objects (humans, dogs, cars, birds) and a use case scenario in medical image analysis. The code is available at https://github.com/MischaD/fobadiffusion.

Complex 3D scene understanding has gained increasing attention, with scene encoding strategies playing a crucial role in this success. However, the optimal scene encoding strategies for various scenarios remain unclear, particularly compared to their image-based counterparts. To address this issue, we present a comprehensive study that probes various visual encoding models for 3D scene understanding, identifying the strengths and limitations of each model across different scenarios. Our evaluation spans seven vision foundation encoders, including image-based, video-based, and 3D foundation models. We evaluate these models in four tasks: Vision-Language Scene Reasoning, Visual Grounding, Segmentation, and Registration, each focusing on different aspects of scene understanding. Our evaluations yield key findings: DINOv2 demonstrates superior performance, video models excel in object-level tasks, diffusion models benefit geometric tasks, and language-pretrained models show unexpected limitations in language-related tasks. These insights challenge some conventional understandings, provide novel perspectives on leveraging visual foundation models, and highlight the need for more flexible encoder selection in future vision-language and scene-understanding tasks.

Self-supervised learning can resolve numerous image or linguistic processing problems when effectively trained. This study investigated simple yet efficient methods for adapting previously learned foundation models for open-vocabulary semantic segmentation tasks. Our research proposed "Beyond-Labels," a lightweight transformer-based fusion module that uses a handful of image segmentation data to fuse frozen image representations with language concepts. This strategy allows the model to successfully actualize enormous knowledge from pretrained models without requiring extensive retraining, making the model data-efficient and scalable. Furthermore, we efficiently captured positional information in images using Fourier embeddings, thus improving the generalization across various image sizes, addressing one of the key limitations of previous methods. Extensive ablation tests were performed to investigate the important components of our proposed method; when tested against the common benchmark PASCAL-5i, it demonstrated superior performance despite being trained on frozen image and language characteristics.

Medical image segmentation aims to delineate the anatomical or pathological structures of interest, playing a crucial role in clinical diagnosis. A substantial amount of high-quality annotated data is crucial for constructing high-precision deep segmentation models. However, medical annotation is highly cumbersome and time-consuming, especially for medical videos or 3D volumes, due to the huge labeling space and poor inter-frame consistency. Recently, a fundamental task named Moving Object Segmentation (MOS) has made significant advancements in natural images. Its objective is to delineate moving objects from the background within image sequences, requiring only minimal annotations. In this paper, we propose the first foundation model, named iMOS, for MOS in medical images. Extensive experiments on a large multi-modal medical dataset validate the effectiveness of the proposed iMOS. Specifically, with the annotation of only a small number of images in the sequence, iMOS can achieve satisfactory tracking and segmentation performance of moving objects throughout the entire sequence in bi-directions. We hope that the proposed iMOS can help accelerate the annotation speed of experts, and boost the development of medical foundation models.

The landscape of publicly available vision foundation models (VFMs), such as CLIP and Segment Anything Model (SAM), is expanding rapidly. VFMs are endowed with distinct capabilities stemming from their pre-training objectives. For instance, CLIP excels in semantic understanding, while SAM specializes in spatial understanding for segmentation. In this work, we introduce a simple recipe to efficiently merge VFMs into a unified model that assimilates their expertise. Our proposed method integrates multi-task learning, continual learning techniques, and teacher-student distillation. This strategy entails significantly less computational cost compared to traditional multi-task training from scratch. Additionally, it only demands a small fraction of the pre-training datasets that were initially used to train individual models. By applying our method to SAM and CLIP, we derive SAM-CLIP: a unified model that amalgamates the strengths of SAM and CLIP into a single backbone, making it apt for edge device applications. We show that SAM-CLIP learns richer visual representations, equipped with both localization and semantic features, suitable for a broad range of vision tasks. SAM-CLIP obtains improved performance on several head probing tasks when compared with SAM and CLIP. We further show that SAM-CLIP not only retains the foundational strengths of its precursor models but also introduces synergistic functionalities, most notably in zero-shot semantic segmentation, where SAM-CLIP establishes new state-of-the-art results on 5 benchmarks. It outperforms previous models that are specifically designed for this task by a large margin, including +6.8% and +5.9% mean IoU improvement on Pascal-VOC and COCO-Stuff datasets, respectively.

Large Vision Language Models (LVLMs) have been widely adopted to guide vision foundation models in performing reasoning segmentation tasks, achieving impressive performance. However, the substantial computational overhead associated with LVLMs presents a new challenge. The primary source of this computational cost arises from processing hundreds of image tokens. Therefore, an effective strategy to mitigate such overhead is to reduce the number of image tokens, a process known as image token pruning. Previous studies on image token pruning for LVLMs have primarily focused on high level visual understanding tasks, such as visual question answering and image captioning. In contrast, guiding vision foundation models to generate accurate visual masks based on textual queries demands precise semantic and spatial reasoning capabilities. Consequently, pruning methods must carefully control individual image tokens throughout the LVLM reasoning process. Our empirical analysis reveals that existing methods struggle to adequately balance reductions in computational overhead with the necessity to maintain high segmentation accuracy. In this work, we propose LVLM_CSP, a novel training free visual token pruning method specifically designed for LVLM based reasoning segmentation tasks. LVLM_CSP consists of three stages: clustering, scattering, and pruning. Initially, the LVLM performs coarse-grained visual reasoning using a subset of selected image tokens. Next, fine grained reasoning is conducted, and finally, most visual tokens are pruned in the last stage. Extensive experiments demonstrate that LVLM_CSP achieves a 65% reduction in image token inference FLOPs with virtually no accuracy degradation, and a 70% reduction with only a minor 1% drop in accuracy on the 7B LVLM.

Recent advances in self-supervised learning for Vision Transformers (ViTs) have fueled breakthroughs in remote sensing (RS) foundation models. However, the quadratic complexity of self-attention poses a significant barrier to scalability, particularly for large models and high-resolution images. While the linear-complexity Mamba architecture offers a promising alternative, existing RS applications of Mamba remain limited to supervised tasks on small, domain-specific datasets. To address these challenges, we propose RoMA, a framework that enables scalable self-supervised pretraining of Mamba-based RS foundation models using large-scale, diverse, unlabeled data. RoMA enhances scalability for high-resolution images through a tailored auto-regressive learning strategy, incorporating two key innovations: 1) a rotation-aware pretraining mechanism combining adaptive cropping with angular embeddings to handle sparsely distributed objects with arbitrary orientations, and 2) multi-scale token prediction objectives that address the extreme variations in object scales inherent to RS imagery. Systematic empirical studies validate that Mamba adheres to RS data and parameter scaling laws, with performance scaling reliably as model and data size increase. Furthermore, experiments across scene classification, object detection, and semantic segmentation tasks demonstrate that RoMA-pretrained Mamba models consistently outperform ViT-based counterparts in both accuracy and computational efficiency. The source code and pretrained models will be released at https://github.com/MiliLab/RoMA.

Geospatial technologies are becoming increasingly essential in our world for a wide range of applications, including agriculture, urban planning, and disaster response. To help improve the applicability and performance of deep learning models on these geospatial tasks, various works have begun investigating foundation models for this domain. Researchers have explored two prominent approaches for introducing such models in geospatial applications, but both have drawbacks in terms of limited performance benefit or prohibitive training cost. Therefore, in this work, we propose a novel paradigm for building highly effective geospatial foundation models with minimal resource cost and carbon impact. We first construct a compact yet diverse dataset from multiple sources to promote feature diversity, which we term GeoPile. Then, we investigate the potential of continual pretraining from large-scale ImageNet-22k models and propose a multi-objective continual pretraining paradigm, which leverages the strong representations of ImageNet while simultaneously providing the freedom to learn valuable in-domain features. Our approach outperforms previous state-of-the-art geospatial pretraining methods in an extensive evaluation on seven downstream datasets covering various tasks such as change detection, classification, multi-label classification, semantic segmentation, and super-resolution.

Massive amounts of unlabelled data are captured by Earth Observation (EO) satellites, with the Sentinel-2 constellation generating 1.6 TB of data daily. This makes Remote Sensing a data-rich domain well suited to Machine Learning (ML) solutions. However, a bottleneck in applying ML models to EO is the lack of annotated data as annotation is a labour-intensive and costly process. As a result, research in this domain has focused on Self-Supervised Learning and Foundation Model approaches. This paper addresses the need to evaluate different Foundation Models on a fair and uniform benchmark by introducing the PhilEO Bench, a novel evaluation framework for EO Foundation Models. The framework comprises of a testbed and a novel 400 GB Sentinel-2 dataset containing labels for three downstream tasks, building density estimation, road segmentation, and land cover classification. We present experiments using our framework evaluating different Foundation Models, including Prithvi and SatMAE, at multiple n-shots and convergence rates.

We introduce a method to train vision-language models for remote-sensing images without using any textual annotations. Our key insight is to use co-located internet imagery taken on the ground as an intermediary for connecting remote-sensing images and language. Specifically, we train an image encoder for remote sensing images to align with the image encoder of CLIP using a large amount of paired internet and satellite images. Our unsupervised approach enables the training of a first-of-its-kind large-scale vision language model (VLM) for remote sensing images at two different resolutions. We show that these VLMs enable zero-shot, open-vocabulary image classification, retrieval, segmentation and visual question answering for satellite images. On each of these tasks, our VLM trained without textual annotations outperforms existing VLMs trained with supervision, with gains of up to 20% for classification and 80% for segmentation.

The Landsat program is the longest-running Earth observation program in history, with 50+ years of data acquisition by 8 satellites. The multispectral imagery captured by sensors onboard these satellites is critical for a wide range of scientific fields. Despite the increasing popularity of deep learning and remote sensing, the majority of researchers still use decision trees and random forests for Landsat image analysis due to the prevalence of small labeled datasets and lack of foundation models. In this paper, we introduce SSL4EO-L, the first ever dataset designed for Self-Supervised Learning for Earth Observation for the Landsat family of satellites (including 3 sensors and 2 product levels) and the largest Landsat dataset in history (5M image patches). Additionally, we modernize and re-release the L7 Irish and L8 Biome cloud detection datasets, and introduce the first ML benchmark datasets for Landsats 4-5 TM and Landsat 7 ETM+ SR. Finally, we pre-train the first foundation models for Landsat imagery using SSL4EO-L and evaluate their performance on multiple semantic segmentation tasks. All datasets and model weights are available via the TorchGeo (https://github.com/microsoft/torchgeo) library, making reproducibility and experimentation easy, and enabling scientific advancements in the burgeoning field of remote sensing for a multitude of downstream applications.

Compared to the great progress of large-scale vision transformers (ViTs) in recent years, large-scale models based on convolutional neural networks (CNNs) are still in an early state. This work presents a new large-scale CNN-based foundation model, termed InternImage, which can obtain the gain from increasing parameters and training data like ViTs. Different from the recent CNNs that focus on large dense kernels, InternImage takes deformable convolution as the core operator, so that our model not only has the large effective receptive field required for downstream tasks such as detection and segmentation, but also has the adaptive spatial aggregation conditioned by input and task information. As a result, the proposed InternImage reduces the strict inductive bias of traditional CNNs and makes it possible to learn stronger and more robust patterns with large-scale parameters from massive data like ViTs. The effectiveness of our model is proven on challenging benchmarks including ImageNet, COCO, and ADE20K. It is worth mentioning that InternImage-H achieved a new record 65.4 mAP on COCO test-dev and 62.9 mIoU on ADE20K, outperforming current leading CNNs and ViTs. The code will be released at https://github.com/OpenGVLab/InternImage.

This research explores the integration of large language models (LLMs) into scientific data assimilation, focusing on combustion science as a case study. Leveraging foundational models integrated with Retrieval-Augmented Generation (RAG) framework, the study introduces an approach to process diverse combustion research data, spanning experimental studies, simulations, and literature. The multifaceted nature of combustion research emphasizes the critical role of knowledge processing in navigating and extracting valuable information from a vast and diverse pool of sources. The developed approach minimizes computational and economic expenses while optimizing data privacy and accuracy. It incorporates prompt engineering and offline open-source LLMs, offering user autonomy in selecting base models. The study provides a thorough examination of text segmentation strategies, conducts comparative studies between LLMs, and explores various optimized prompts to demonstrate the effectiveness of the framework. By incorporating an external database, the framework outperforms a conventional LLM in generating accurate responses and constructing robust arguments. Additionally, the study delves into the investigation of optimized prompt templates for the purpose of efficient extraction of scientific literature. The research addresses concerns related to hallucinations and false research articles by introducing a custom workflow developed with a detection algorithm to filter out inaccuracies. Despite identified areas for improvement, the framework consistently delivers accurate domain-specific responses with minimal human oversight. The prompt-agnostic approach introduced holds promise for future deliberations. The study underscores the significance of integrating LLMs and knowledge processing techniques in scientific research, providing a foundation for advancements in data assimilation and utilization.

When trained at a sufficient scale, self-supervised learning has exhibited a notable ability to solve a wide range of visual or language understanding tasks. In this paper, we investigate simple, yet effective approaches for adapting the pre-trained foundation models to the downstream task of interest, namely, open-vocabulary semantic segmentation. To this end, we make the following contributions: (i) we introduce Fusioner, with a lightweight, transformer-based fusion module, that pairs the frozen visual representation with language concept through a handful of image segmentation data. As a consequence, the model gains the capability of zero-shot transfer to segment novel categories; (ii) without loss of generality, we experiment on a broad range of self-supervised models that have been pre-trained with different schemes, e.g. visual-only models (MoCo v3, DINO), language-only models (BERT), visual-language model (CLIP), and show that, the proposed fusion approach is effective to any pair of visual and language models, even those pre-trained on a corpus of uni-modal data; (iii) we conduct thorough ablation studies to analyze the critical components in our proposed Fusioner, while evaluating on standard benchmarks, e.g. PASCAL-5i and COCO-20i , it surpasses existing state-of-the-art models by a large margin, despite only being trained on frozen visual and language features; (iv) to measure the model's robustness on learning visual-language correspondence, we further evaluate on synthetic dataset, named Mosaic-4, where images are constructed by mosaicking the samples from FSS-1000. Fusioner demonstrates superior performance over previous models.

Multiple works have emerged to push the boundaries on multi-modal large language models (MLLMs) towards pixel-level understanding. Such approaches have shown strong performance on benchmarks for referring expression segmentation and grounded conversation generation. The current trend in pixel-level MLLMs is to train with pixel-level grounding supervision on large-scale labelled data. However, we show that such MLLMs when evaluated on recent challenging vision centric benchmarks, exhibit a weak ability in visual question answering. Surprisingly, some of these methods even downgrade the grounding ability of MLLMs that were never trained with such supervision. In this work, we propose two novel challenging benchmarks and show that MLLMs without pixel-level grounding supervision can outperform the state of the art in such tasks when evaluating both the pixel-level grounding and visual question answering. We propose simple baselines to extract the grounding information that can be plugged into any MLLM, which we call as PixFoundation. More importantly, we study the research question of "When does grounding emerge in MLLMs that are not trained with pixel-level grounding supervision?" We show that grounding can coincide with object parts or location/appearance information. Code repository is at https://github.com/MSiam/PixFoundation/.

Self-supervised learning (SSL) has revolutionized representation learning in Remote Sensing (RS), advancing Geospatial Foundation Models (GFMs) to leverage vast unlabeled satellite imagery for diverse downstream tasks. Currently, GFMs primarily focus on discriminative objectives, such as contrastive learning or masked image modeling, owing to their proven success in learning transferable representations. However, generative diffusion models--which demonstrate the potential to capture multi-grained semantics essential for RS tasks during image generation--remain underexplored for discriminative applications. This prompts the question: can generative diffusion models also excel and serve as GFMs with sufficient discriminative power? In this work, we answer this question with SatDiFuser, a framework that transforms a diffusion-based generative geospatial foundation model into a powerful pretraining tool for discriminative RS. By systematically analyzing multi-stage, noise-dependent diffusion features, we develop three fusion strategies to effectively leverage these diverse representations. Extensive experiments on remote sensing benchmarks show that SatDiFuser outperforms state-of-the-art GFMs, achieving gains of up to +5.7% mIoU in semantic segmentation and +7.9% F1-score in classification, demonstrating the capacity of diffusion-based generative foundation models to rival or exceed discriminative GFMs. Code will be released.

Foundation models have revolutionized computer vision by achieving vastly superior performance across diverse tasks through large-scale pretraining on extensive datasets. However, their application in surgical computer vision has been limited. This study addresses this gap by introducing SurgeNetXL, a novel surgical foundation model that sets a new benchmark in surgical computer vision. Trained on the largest reported surgical dataset to date, comprising over 4.7 million video frames, SurgeNetXL achieves consistent top-tier performance across six datasets spanning four surgical procedures and three tasks, including semantic segmentation, phase recognition, and critical view of safety (CVS) classification. Compared with the best-performing surgical foundation models, SurgeNetXL shows mean improvements of 2.4, 9.0, and 12.6 percent for semantic segmentation, phase recognition, and CVS classification, respectively. Additionally, SurgeNetXL outperforms the best-performing ImageNet-based variants by 14.4, 4.0, and 1.6 percent in the respective tasks. In addition to advancing model performance, this study provides key insights into scaling pretraining datasets, extending training durations, and optimizing model architectures specifically for surgical computer vision. These findings pave the way for improved generalizability and robustness in data-scarce scenarios, offering a comprehensive framework for future research in this domain. All models and a subset of the SurgeNetXL dataset, including over 2 million video frames, are publicly available at: https://github.com/TimJaspers0801/SurgeNet.

Semantic mapping based on the supervised object detectors is sensitive to image distribution. In real-world environments, the object detection and segmentation performance can lead to a major drop, preventing the use of semantic mapping in a wider domain. On the other hand, the development of vision-language foundation models demonstrates a strong zero-shot transferability across data distribution. It provides an opportunity to construct generalizable instance-aware semantic maps. Hence, this work explores how to boost instance-aware semantic mapping from object detection generated from foundation models. We propose a probabilistic label fusion method to predict close-set semantic classes from open-set label measurements. An instance refinement module merges the over-segmented instances caused by inconsistent segmentation. We integrate all the modules into a unified semantic mapping system. Reading a sequence of RGB-D input, our work incrementally reconstructs an instance-aware semantic map. We evaluate the zero-shot performance of our method in ScanNet and SceneNN datasets. Our method achieves 40.3 mean average precision (mAP) on the ScanNet semantic instance segmentation task. It outperforms the traditional semantic mapping method significantly.

Multimodal foundation models, such as GPT-4o, have recently made remarkable progress, but it is not clear where exactly these models stand in terms of understanding vision. In this paper, we benchmark the performance of popular multimodal foundation models (GPT-4o, o4-mini, Gemini 1.5 Pro and Gemini 2.0 Flash, Claude 3.5 Sonnet, Qwen2-VL, Llama 3.2) on standard computer vision tasks (semantic segmentation, object detection, image classification, depth and surface normal prediction) using established datasets (e.g., COCO, ImageNet and its variants, etc). The main challenges to performing this are: 1) most models are trained to output text and cannot natively express versatile domains, such as segments or 3D geometry, and 2) many leading models are proprietary and accessible only at an API level, i.e., there is no weight access to adapt them. We address these challenges by translating standard vision tasks into equivalent text-promptable and API-compatible tasks via prompt chaining to create a standardized benchmarking framework. We observe that 1) the models are not close to the state-of-the-art specialist models at any task. However, 2) they are respectable generalists; this is remarkable as they are presumably trained on primarily image-text-based tasks. 3) They perform semantic tasks notably better than geometric ones. 4) While the prompt-chaining techniques affect performance, better models exhibit less sensitivity to prompt variations. 5) GPT-4o performs the best among non-reasoning models, securing the top position in 4 out of 6 tasks, 6) reasoning models, e.g. o3, show improvements in geometric tasks, and 7) a preliminary analysis of models with native image generation, like the latest GPT-4o, shows they exhibit quirks like hallucinations and spatial misalignments.

Accurate and efficient 3D segmentation is essential for both clinical and research applications. While foundation models like SAM have revolutionized interactive segmentation, their 2D design and domain shift limitations make them ill-suited for 3D medical images. Current adaptations address some of these challenges but remain limited, either lacking volumetric awareness, offering restricted interactivity, or supporting only a small set of structures and modalities. Usability also remains a challenge, as current tools are rarely integrated into established imaging platforms and often rely on cumbersome web-based interfaces with restricted functionality. We introduce nnInteractive, the first comprehensive 3D interactive open-set segmentation method. It supports diverse prompts-including points, scribbles, boxes, and a novel lasso prompt-while leveraging intuitive 2D interactions to generate full 3D segmentations. Trained on 120+ diverse volumetric 3D datasets (CT, MRI, PET, 3D Microscopy, etc.), nnInteractive sets a new state-of-the-art in accuracy, adaptability, and usability. Crucially, it is the first method integrated into widely used image viewers (e.g., Napari, MITK), ensuring broad accessibility for real-world clinical and research applications. Extensive benchmarking demonstrates that nnInteractive far surpasses existing methods, setting a new standard for AI-driven interactive 3D segmentation. nnInteractive is publicly available: https://github.com/MIC-DKFZ/napari-nninteractive (Napari plugin), https://www.mitk.org/MITK-nnInteractive (MITK integration), https://github.com/MIC-DKFZ/nnInteractive (Python backend).

Large multimodal foundation models, particularly in the domains of language and vision, have significantly advanced various tasks, including robotics, autonomous driving, information retrieval, and grounding. However, many of these models perceive objects as indivisible, overlooking the components that constitute them. Understanding these components and their associated affordances provides valuable insights into an object's functionality, which is fundamental for performing a wide range of tasks. In this work, we introduce a novel real-world benchmark, InstructPart, comprising hand-labeled part segmentation annotations and task-oriented instructions to evaluate the performance of current models in understanding and executing part-level tasks within everyday contexts. Through our experiments, we demonstrate that task-oriented part segmentation remains a challenging problem, even for state-of-the-art Vision-Language Models (VLMs). In addition to our benchmark, we introduce a simple baseline that achieves a twofold performance improvement through fine-tuning with our dataset. With our dataset and benchmark, we aim to facilitate research on task-oriented part segmentation and enhance the applicability of VLMs across various domains, including robotics, virtual reality, information retrieval, and other related fields. Project website: https://zifuwan.github.io/InstructPart/.

Foundation models have emerged as powerful tools across various domains including language, vision, and multimodal tasks. While prior works have addressed unsupervised image segmentation, they significantly lag behind supervised models. In this paper, we use a diffusion UNet encoder as a foundation vision encoder and introduce DiffCut, an unsupervised zero-shot segmentation method that solely harnesses the output features from the final self-attention block. Through extensive experimentation, we demonstrate that the utilization of these diffusion features in a graph based segmentation algorithm, significantly outperforms previous state-of-the-art methods on zero-shot segmentation. Specifically, we leverage a recursive Normalized Cut algorithm that softly regulates the granularity of detected objects and produces well-defined segmentation maps that precisely capture intricate image details. Our work highlights the remarkably accurate semantic knowledge embedded within diffusion UNet encoders that could then serve as foundation vision encoders for downstream tasks. Project page at https://diffcut-segmentation.github.io

The development of 2D foundation models for image segmentation has been significantly advanced by the Segment Anything Model (SAM). However, achieving similar success in 3D models remains a challenge due to issues such as non-unified data formats, lightweight models, and the scarcity of labeled data with diverse masks. To this end, we propose a 3D promptable segmentation model (Point-SAM) focusing on point clouds. Our approach utilizes a transformer-based method, extending SAM to the 3D domain. We leverage part-level and object-level annotations and introduce a data engine to generate pseudo labels from SAM, thereby distilling 2D knowledge into our 3D model. Our model outperforms state-of-the-art models on several indoor and outdoor benchmarks and demonstrates a variety of applications, such as 3D annotation. Codes and demo can be found at https://github.com/zyc00/Point-SAM.

Foundation models like the Segment Anything Model (SAM) have significantly advanced promptable image segmentation in computer vision. However, extending these capabilities to videos presents substantial challenges, particularly in ensuring precise and temporally consistent mask propagation in dynamic scenes. SAM 2 attempts to address this by training a model on massive image and video data from scratch to learn complex spatiotemporal associations, resulting in huge training costs that hinder research and practical deployment. In this paper, we introduce SAM-I2V, an effective image-to-video upgradation method for cultivating a promptable video segmentation (PVS) model. Our approach strategically upgrades the pre-trained SAM to support PVS, significantly reducing training complexity and resource requirements. To achieve this, we introduce three key innovations: (i) an image-to-video feature extraction upgrader built upon SAM's static image encoder to enable spatiotemporal video perception, (ii) a memory filtering strategy that selects the most relevant past frames for more effective utilization of historical information, and (iii) a memory-as-prompt mechanism leveraging object memory to ensure temporally consistent mask propagation in dynamic scenes. Comprehensive experiments demonstrate that our method achieves over 90% of SAM 2's performance while using only 0.2% of its training cost. Our work presents a resource-efficient pathway to PVS, lowering barriers for further research in PVS model design and enabling broader applications and advancements in the field. Code and model are available at: https://github.com/showlab/SAM-I2V.

Segmentation models can recognize a pre-defined set of objects in images. However, models that can reason over complex user queries that implicitly refer to multiple objects of interest are still in their infancy. Recent advances in reasoning segmentation--generating segmentation masks from complex, implicit query text--demonstrate that vision-language models can operate across an open domain and produce reasonable outputs. However, our experiments show that such models struggle with complex remote-sensing imagery. In this work, we introduce LISAt, a vision-language model designed to describe complex remote-sensing scenes, answer questions about them, and segment objects of interest. We trained LISAt on a new curated geospatial reasoning-segmentation dataset, GRES, with 27,615 annotations over 9,205 images, and a multimodal pretraining dataset, PreGRES, containing over 1 million question-answer pairs. LISAt outperforms existing geospatial foundation models such as RS-GPT4V by over 10.04 % (BLEU-4) on remote-sensing description tasks, and surpasses state-of-the-art open-domain models on reasoning segmentation tasks by 143.36 % (gIoU). Our model, datasets, and code are available at https://lisat-bair.github.io/LISAt/

3D object part segmentation is essential in computer vision applications. While substantial progress has been made in 2D object part segmentation, the 3D counterpart has received less attention, in part due to the scarcity of annotated 3D datasets, which are expensive to collect. In this work, we propose to leverage a few annotated 3D shapes or richly annotated 2D datasets to perform 3D object part segmentation. We present our novel approach, termed 3-By-2 that achieves SOTA performance on different benchmarks with various granularity levels. By using features from pretrained foundation models and exploiting semantic and geometric correspondences, we are able to overcome the challenges of limited 3D annotations. Our approach leverages available 2D labels, enabling effective 3D object part segmentation. Our method 3-By-2 can accommodate various part taxonomies and granularities, demonstrating interesting part label transfer ability across different object categories. Project website: https://ngailapdi.github.io/projects/3by2/.

Large-scale vision foundation models such as Segment Anything (SAM) demonstrate impressive performance in zero-shot image segmentation at multiple levels of granularity. However, these zero-shot predictions are rarely 3D-consistent. As the camera viewpoint changes in a scene, so do the segmentation predictions, as well as the characterizations of "coarse" or "fine" granularity. In this work, we address the challenging task of lifting multi-granular and view-inconsistent image segmentations into a hierarchical and 3D-consistent representation. We learn a novel feature field within a Neural Radiance Field (NeRF) representing a 3D scene, whose segmentation structure can be revealed at different scales by simply using different thresholds on feature distance. Our key idea is to learn an ultrametric feature space, which unlike a Euclidean space, exhibits transitivity in distance-based grouping, naturally leading to a hierarchical clustering. Put together, our method takes view-inconsistent multi-granularity 2D segmentations as input and produces a hierarchy of 3D-consistent segmentations as output. We evaluate our method and several baselines on synthetic datasets with multi-view images and multi-granular segmentation, showcasing improved accuracy and viewpoint-consistency. We additionally provide qualitative examples of our model's 3D hierarchical segmentations in real world scenes. The code and dataset are available at https://github.com/hardyho/ultrametric_feature_fields

The advent of foundation models, which are pre-trained on vast datasets, has ushered in a new era of computer vision, characterized by their robustness and remarkable zero-shot generalization capabilities. Mirroring the transformative impact of foundation models like large language models (LLMs) in natural language processing, visual foundation models (VFMs) have become a catalyst for groundbreaking developments in computer vision. This review paper delineates the pivotal trajectories of VFMs, emphasizing their scalability and proficiency in generative tasks such as text-to-image synthesis, as well as their adeptness in discriminative tasks including image segmentation. While generative and discriminative models have historically charted distinct paths, we undertake a comprehensive examination of the recent strides made by VFMs in both domains, elucidating their origins, seminal breakthroughs, and pivotal methodologies. Additionally, we collate and discuss the extensive resources that facilitate the development of VFMs and address the challenges that pave the way for future research endeavors. A crucial direction for forthcoming innovation is the amalgamation of generative and discriminative paradigms. The nascent application of generative models within discriminative contexts signifies the early stages of this confluence. This survey aspires to be a contemporary compendium for scholars and practitioners alike, charting the course of VFMs and illuminating their multifaceted landscape.

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic tool. In the past decade, there has been an increase in the use of machine learning, particularly deep learning, for medical images processing. Thanks to the development of foundation models, models pre-trained with large-scale datasets have achieved better results on a variety of tasks. However, for medical images with small dataset sizes, deep learning methods struggle to achieve better results on real-world image datasets. In this paper, we propose a cross-modality attention adapter based on multimodal fusion to fine-tune the foundation model to accomplish the task of glioma segmentation in multimodal MRI brain images with better results. The effectiveness of the proposed method is validated via our private glioma data set from the First Affiliated Hospital of Zhengzhou University (FHZU) in Zhengzhou, China. Our proposed method is superior to current state-of-the-art methods with a Dice of 88.38% and Hausdorff distance of 10.64, thereby exhibiting a 4% increase in Dice to segment the glioma region for glioma treatment.

We propose a simple three-stage approach to segment unseen objects in RGB images using their CAD models. Leveraging recent powerful foundation models, DINOv2 and Segment Anything, we create descriptors and generate proposals, including binary masks for a given input RGB image. By matching proposals with reference descriptors created from CAD models, we achieve precise object ID assignment along with modal masks. We experimentally demonstrate that our method achieves state-of-the-art results in CAD-based novel object segmentation, surpassing existing approaches on the seven core datasets of the BOP challenge by 19.8\% AP using the same BOP evaluation protocol. Our source code is available at https://github.com/nv-nguyen/cnos.

The deployment of foundation models for medical imaging has demonstrated considerable success. However, their training overheads associated with downstream tasks remain substantial due to the size of the image encoders employed, and the inference complexity is also significantly high. Although lightweight variants have been obtained for these foundation models, their performance is constrained by their limited model capacity and suboptimal training strategies. In order to achieve an improved tradeoff between complexity and performance, we propose a new framework to improve the performance of low complexity models via knowledge distillation from multiple large medical foundation models (e.g., MedSAM, RAD-DINO, MedCLIP), each specializing in different vision tasks, with the goal to effectively bridge the performance gap for medical image segmentation tasks. The agglomerated model demonstrates superior generalization across 12 segmentation tasks, whereas specialized models require explicit training for each task. Our approach achieved an average performance gain of 2\% in Dice coefficient compared to simple distillation.

The open-vocabulary image segmentation task involves partitioning images into semantically meaningful segments and classifying them with flexible text-defined categories. The recent vision-based foundation models such as the Segment Anything Model (SAM) have shown superior performance in generating class-agnostic image segments. The main challenge in open-vocabulary image segmentation now lies in accurately classifying these segments into text-defined categories. In this paper, we introduce the Universal Segment Embedding (USE) framework to address this challenge. This framework is comprised of two key components: 1) a data pipeline designed to efficiently curate a large amount of segment-text pairs at various granularities, and 2) a universal segment embedding model that enables precise segment classification into a vast range of text-defined categories. The USE model can not only help open-vocabulary image segmentation but also facilitate other downstream tasks (e.g., querying and ranking). Through comprehensive experimental studies on semantic segmentation and part segmentation benchmarks, we demonstrate that the USE framework outperforms state-of-the-art open-vocabulary segmentation methods.

Transformer-like models for vision tasks have recently proven effective for a wide range of downstream applications such as segmentation and detection. Previous works have shown that segmentation properties emerge in vision transformers (ViTs) trained using self-supervised methods such as DINO, but not in those trained on supervised classification tasks. In this study, we probe whether segmentation emerges in transformer-based models solely as a result of intricate self-supervised learning mechanisms, or if the same emergence can be achieved under much broader conditions through proper design of the model architecture. Through extensive experimental results, we demonstrate that when employing a white-box transformer-like architecture known as CRATE, whose design explicitly models and pursues low-dimensional structures in the data distribution, segmentation properties, at both the whole and parts levels, already emerge with a minimalistic supervised training recipe. Layer-wise finer-grained analysis reveals that the emergent properties strongly corroborate the designed mathematical functions of the white-box network. Our results suggest a path to design white-box foundation models that are simultaneously highly performant and mathematically fully interpretable. Code is at https://github.com/Ma-Lab-Berkeley/CRATE.

In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised learning (SSL) enhances the utilization of unlabeled data by facilitating knowledge transfer, significantly improving the performance of fully supervised models and emerging as a highly promising research direction in medical image analysis. Inspired by the ability of Vision Foundation Models (e.g., SAM-2) to provide rich prior knowledge, we propose SSS (Semi-Supervised SAM-2), a novel approach that leverages SAM-2's robust feature extraction capabilities to uncover latent knowledge in unlabeled medical images, thus effectively enhancing feature support for fully supervised medical image segmentation. Specifically, building upon the single-stream "weak-to-strong" consistency regularization framework, this paper introduces a Discriminative Feature Enhancement (DFE) mechanism to further explore the feature discrepancies introduced by various data augmentation strategies across multiple views. By leveraging feature similarity and dissimilarity across multi-scale augmentation techniques, the method reconstructs and models the features, thereby effectively optimizing the salient regions. Furthermore, a prompt generator is developed that integrates Physical Constraints with a Sliding Window (PCSW) mechanism to generate input prompts for unlabeled data, fulfilling SAM-2's requirement for additional prompts. Extensive experiments demonstrate the superiority of the proposed method for semi-supervised medical image segmentation on two multi-label datasets, i.e., ACDC and BHSD. Notably, SSS achieves an average Dice score of 53.15 on BHSD, surpassing the previous state-of-the-art method by +3.65 Dice. Code will be available at https://github.com/AIGeeksGroup/SSS.

Few-shot semantic segmentation has gained increasing interest due to its generalization capability, i.e., segmenting pixels of novel classes requiring only a few annotated images. Prior work has focused on meta-learning for support-query matching, with extensive development in both prototype-based and aggregation-based methods. To address data scarcity, recent approaches have turned to foundation models to enhance representation transferability for novel class segmentation. Among them, a hybrid dual-modal framework including both DINOv2 and SAM has garnered attention due to their complementary capabilities. We wonder "can we build a unified model with knowledge from both foundation models?" To this end, we propose FS-DINO, with only DINOv2's encoder and a lightweight segmenter. The segmenter features a bottleneck adapter, a meta-visual prompt generator based on dense similarities and semantic embeddings, and a decoder. Through coarse-to-fine cross-model distillation, we effectively integrate SAM's knowledge into our lightweight segmenter, which can be further enhanced by 4D correlation mining on support-query pairs. Extensive experiments on COCO-20i, PASCAL-5i, and FSS-1000 demonstrate the effectiveness and superiority of our method.

In this paper, we address the challenge of performing open-vocabulary video instance segmentation (OV-VIS) in real-time. We analyze the computational bottlenecks of state-of-the-art foundation models that performs OV-VIS, and propose a new method, TROY-VIS, that significantly improves processing speed while maintaining high accuracy. We introduce three key techniques: (1) Decoupled Attention Feature Enhancer to speed up information interaction between different modalities and scales; (2) Flash Embedding Memory for obtaining fast text embeddings of object categories; and, (3) Kernel Interpolation for exploiting the temporal continuity in videos. Our experiments demonstrate that TROY-VIS achieves the best trade-off between accuracy and speed on two large-scale OV-VIS benchmarks, BURST and LV-VIS, running 20x faster than GLEE-Lite (25 FPS v.s. 1.25 FPS) with comparable or even better accuracy. These results demonstrate TROY-VIS's potential for real-time applications in dynamic environments such as mobile robotics and augmented reality. Code and model will be released at https://github.com/google-research/troyvis.

Large-scale pre-training tasks like image classification, captioning, or self-supervised techniques do not incentivize learning the semantic boundaries of objects. However, recent generative foundation models built using text-based latent diffusion techniques may learn semantic boundaries. This is because they have to synthesize intricate details about all objects in an image based on a text description. Therefore, we present a technique for segmenting real and AI-generated images using latent diffusion models (LDMs) trained on internet-scale datasets. First, we show that the latent space of LDMs (z-space) is a better input representation compared to other feature representations like RGB images or CLIP encodings for text-based image segmentation. By training the segmentation models on the latent z-space, which creates a compressed representation across several domains like different forms of art, cartoons, illustrations, and photographs, we are also able to bridge the domain gap between real and AI-generated images. We show that the internal features of LDMs contain rich semantic information and present a technique in the form of LD-ZNet to further boost the performance of text-based segmentation. Overall, we show up to 6% improvement over standard baselines for text-to-image segmentation on natural images. For AI-generated imagery, we show close to 20% improvement compared to state-of-the-art techniques. The project is available at https://koutilya-pnvr.github.io/LD-ZNet/.

In the domain of computer vision, Parameter-Efficient Tuning (PET) is increasingly replacing the traditional paradigm of pre-training followed by full fine-tuning. PET is particularly favored for its effectiveness in large foundation models, as it streamlines transfer learning costs and optimizes hardware utilization. However, the current PET methods are mainly designed for single-modal optimization. While some pioneering studies have undertaken preliminary explorations, they still remain at the level of aligned encoders (e.g., CLIP) and lack exploration of misaligned encoders. These methods show sub-optimal performance with misaligned encoders, as they fail to effectively align the multimodal features during fine-tuning. In this paper, we introduce DETRIS, a parameter-efficient tuning framework designed to enhance low-rank visual feature propagation by establishing dense interconnections between each layer and all preceding layers, which enables effective cross-modal feature interaction and adaptation to misaligned encoders. We also suggest using text adapters to improve textual features. Our simple yet efficient approach greatly surpasses state-of-the-art methods with 0.9% to 1.8% backbone parameter updates, evaluated on challenging benchmarks. Our project is available at https://github.com/jiaqihuang01/DETRIS.

The Segment Anything Model (SAM) represents a significant breakthrough into foundation models for computer vision, providing a large-scale image segmentation model. However, despite SAM's zero-shot performance, its segmentation masks lack fine-grained details, particularly in accurately delineating object boundaries. Therefore, it is both interesting and valuable to explore whether SAM can be improved towards highly accurate object segmentation, which is known as the dichotomous image segmentation (DIS) task. To address this issue, we propose DIS-SAM, which advances SAM towards DIS with extremely accurate details. DIS-SAM is a framework specifically tailored for highly accurate segmentation, maintaining SAM's promptable design. DIS-SAM employs a two-stage approach, integrating SAM with a modified advanced network that was previously designed to handle the prompt-free DIS task. To better train DIS-SAM, we employ a ground truth enrichment strategy by modifying original mask annotations. Despite its simplicity, DIS-SAM significantly advances the SAM, HQ-SAM, and Pi-SAM ~by 8.5%, ~6.9%, and ~3.7% maximum F-measure. Our code at https://github.com/Tennine2077/DIS-SAM

Open-vocabulary segmentation of 3D scenes is a fundamental function of human perception and thus a crucial objective in computer vision research. However, this task is heavily impeded by the lack of large-scale and diverse 3D open-vocabulary segmentation datasets for training robust and generalizable models. Distilling knowledge from pre-trained 2D open-vocabulary segmentation models helps but it compromises the open-vocabulary feature as the 2D models are mostly finetuned with close-vocabulary datasets. We tackle the challenges in 3D open-vocabulary segmentation by exploiting pre-trained foundation models CLIP and DINO in a weakly supervised manner. Specifically, given only the open-vocabulary text descriptions of the objects in a scene, we distill the open-vocabulary multimodal knowledge and object reasoning capability of CLIP and DINO into a neural radiance field (NeRF), which effectively lifts 2D features into view-consistent 3D segmentation. A notable aspect of our approach is that it does not require any manual segmentation annotations for either the foundation models or the distillation process. Extensive experiments show that our method even outperforms fully supervised models trained with segmentation annotations in certain scenes, suggesting that 3D open-vocabulary segmentation can be effectively learned from 2D images and text-image pairs. Code is available at https://github.com/Kunhao-Liu/3D-OVS.

Object detection has been expanded from a limited number of categories to open vocabulary. Moving forward, a complete intelligent vision system requires understanding more fine-grained object descriptions, object parts. In this paper, we propose a detector with the ability to predict both open-vocabulary objects and their part segmentation. This ability comes from two designs. First, we train the detector on the joint of part-level, object-level and image-level data to build the multi-granularity alignment between language and image. Second, we parse the novel object into its parts by its dense semantic correspondence with the base object. These two designs enable the detector to largely benefit from various data sources and foundation models. In open-vocabulary part segmentation experiments, our method outperforms the baseline by 3.3sim7.3 mAP in cross-dataset generalization on PartImageNet, and improves the baseline by 7.3 novel AP_{50} in cross-category generalization on Pascal Part. Finally, we train a detector that generalizes to a wide range of part segmentation datasets while achieving better performance than dataset-specific training.

Referring video object segmentation (RVOS) aims to segment target objects throughout a video based on a text description. Despite notable progress in recent years, current RVOS models remain struggle to handle complicated object descriptions due to their limited video-language understanding. To address this limitation, we present ReferDINO, an end-to-end RVOS model that inherits strong vision-language understanding from the pretrained visual grounding foundation models, and is further endowed with effective temporal understanding and object segmentation capabilities. In ReferDINO, we contribute three technical innovations for effectively adapting the foundation models to RVOS: 1) an object-consistent temporal enhancer that capitalizes on the pretrained object-text representations to enhance temporal understanding and object consistency; 2) a grounding-guided deformable mask decoder that integrates text and grounding conditions to generate accurate object masks; 3) a confidence-aware query pruning strategy that significantly improves the object decoding efficiency without compromising performance. We conduct extensive experiments on five public RVOS benchmarks to demonstrate that our proposed ReferDINO outperforms state-of-the-art methods significantly. Project page: https://isee-laboratory.github.io/ReferDINO

The emergence of large models, also known as foundation models, has brought significant advancements to AI research. One such model is Segment Anything (SAM), which is designed for image segmentation tasks. However, as with other foundation models, our experimental findings suggest that SAM may fail or perform poorly in certain segmentation tasks, such as shadow detection and camouflaged object detection (concealed object detection). This study first paves the way for applying the large pre-trained image segmentation model SAM to these downstream tasks, even in situations where SAM performs poorly. Rather than fine-tuning the SAM network, we propose SAM-Adapter, which incorporates domain-specific information or visual prompts into the segmentation network by using simple yet effective adapters. By integrating task-specific knowledge with general knowledge learnt by the large model, SAM-Adapter can significantly elevate the performance of SAM in challenging tasks as shown in extensive experiments. We can even outperform task-specific network models and achieve state-of-the-art performance in the task we tested: camouflaged object detection, shadow detection. We also tested polyp segmentation (medical image segmentation) and achieves better results. We believe our work opens up opportunities for utilizing SAM in downstream tasks, with potential applications in various fields, including medical image processing, agriculture, remote sensing, and more.

In the realm of fashion object detection and segmentation for online shopping images, existing state-of-the-art fashion parsing models encounter limitations, particularly when exposed to non-model-worn apparel and close-up shots. To address these failures, we introduce FashionFail; a new fashion dataset with e-commerce images for object detection and segmentation. The dataset is efficiently curated using our novel annotation tool that leverages recent foundation models. The primary objective of FashionFail is to serve as a test bed for evaluating the robustness of models. Our analysis reveals the shortcomings of leading models, such as Attribute-Mask R-CNN and Fashionformer. Additionally, we propose a baseline approach using naive data augmentation to mitigate common failure cases and improve model robustness. Through this work, we aim to inspire and support further research in fashion item detection and segmentation for industrial applications. The dataset, annotation tool, code, and models are available at https://rizavelioglu.github.io/fashionfail/.

We present a framework for perspective-aware reasoning in vision-language models (VLMs) through mental imagery simulation. Perspective-taking, the ability to perceive an environment or situation from an alternative viewpoint, is a key benchmark for human-level visual understanding, essential for environmental interaction and collaboration with autonomous agents. Despite advancements in spatial reasoning within VLMs, recent research has shown that modern VLMs significantly lack perspective-aware reasoning capabilities and exhibit a strong bias toward egocentric interpretations. To bridge the gap between VLMs and human perception, we focus on the role of mental imagery, where humans perceive the world through abstracted representations that facilitate perspective shifts. Motivated by this, we propose a framework for perspective-aware reasoning, named Abstract Perspective Change (APC), that effectively leverages vision foundation models, such as object detection, segmentation, and orientation estimation, to construct scene abstractions and enable perspective transformations. Our experiments on synthetic and real-image benchmarks, compared with various VLMs, demonstrate significant improvements in perspective-aware reasoning with our framework, further outperforming fine-tuned spatial reasoning models and novel-view-synthesis-based approaches.

Large-scale vision-language models like CLIP have demonstrated impressive open-vocabulary capabilities for image-level tasks, excelling in recognizing what objects are present. However, they struggle with pixel-level recognition tasks like semantic segmentation, which additionally require understanding where the objects are located. In this work, we propose a novel method, PixelCLIP, to adapt the CLIP image encoder for pixel-level understanding by guiding the model on where, which is achieved using unlabeled images and masks generated from vision foundation models such as SAM and DINO. To address the challenges of leveraging masks without semantic labels, we devise an online clustering algorithm using learnable class names to acquire general semantic concepts. PixelCLIP shows significant performance improvements over CLIP and competitive results compared to caption-supervised methods in open-vocabulary semantic segmentation. Project page is available at https://cvlab-kaist.github.io/PixelCLIP

Recent success of pre-trained foundation vision-language models makes Open-Vocabulary Segmentation (OVS) possible. Despite the promising performance, this approach introduces heavy computational overheads for two challenges: 1) large model sizes of the backbone; 2) expensive costs during the fine-tuning. These challenges hinder this OVS strategy from being widely applicable and affordable in real-world scenarios. Although traditional methods such as model compression and efficient fine-tuning can address these challenges, they often rely on heuristics. This means that their solutions cannot be easily transferred and necessitate re-training on different models, which comes at a cost. In the context of efficient OVS, we target achieving performance that is comparable to or even better than prior OVS works based on large vision-language foundation models, by utilizing smaller models that incur lower training costs. The core strategy is to make our efficiency principled and thus seamlessly transferable from one OVS framework to others without further customization. Comprehensive experiments on diverse OVS benchmarks demonstrate our superior trade-off between segmentation accuracy and computation costs over previous works. Our code is available on https://github.com/Xujxyang/OpenTrans

Vision-Language Model (VLM) have gained widespread adoption in Open-Vocabulary (OV) object detection and segmentation tasks. Despite they have shown promise on OV-related tasks, their effectiveness in conventional vision tasks has thus far been unevaluated. In this work, we present the systematic review of VLM-based detection and segmentation, view VLM as the foundational model and conduct comprehensive evaluations across multiple downstream tasks for the first time: 1) The evaluation spans eight detection scenarios (closed-set detection, domain adaptation, crowded objects, etc.) and eight segmentation scenarios (few-shot, open-world, small object, etc.), revealing distinct performance advantages and limitations of various VLM architectures across tasks. 2) As for detection tasks, we evaluate VLMs under three finetuning granularities: zero prediction, visual fine-tuning, and text prompt, and further analyze how different finetuning strategies impact performance under varied task. 3) Based on empirical findings, we provide in-depth analysis of the correlations between task characteristics, model architectures, and training methodologies, offering insights for future VLM design. 4) We believe that this work shall be valuable to the pattern recognition experts working in the fields of computer vision, multimodal learning, and vision foundation models by introducing them to the problem, and familiarizing them with the current status of the progress while providing promising directions for future research. A project associated with this review and evaluation has been created at https://github.com/better-chao/perceptual_abilities_evaluation.

Obtaining accurate labels for instance segmentation is particularly challenging due to the complex nature of the task. Each image necessitates multiple annotations, encompassing not only the object's class but also its precise spatial boundaries. These requirements elevate the likelihood of errors and inconsistencies in both manual and automated annotation processes. By simulating different noise conditions, we provide a realistic scenario for assessing the robustness and generalization capabilities of instance segmentation models in different segmentation tasks, introducing COCO-N and Cityscapes-N. We also propose a benchmark for weakly annotation noise, dubbed COCO-WAN, which utilizes foundation models and weak annotations to simulate semi-automated annotation tools and their noisy labels. This study sheds light on the quality of segmentation masks produced by various models and challenges the efficacy of popular methods designed to address learning with label noise.

Recent works on open-vocabulary 3D instance segmentation show strong promise, but at the cost of slow inference speed and high computation requirements. This high computation cost is typically due to their heavy reliance on 3D clip features, which require computationally expensive 2D foundation models like Segment Anything (SAM) and CLIP for multi-view aggregation into 3D. As a consequence, this hampers their applicability in many real-world applications that require both fast and accurate predictions. To this end, we propose a fast yet accurate open-vocabulary 3D instance segmentation approach, named Open-YOLO 3D, that effectively leverages only 2D object detection from multi-view RGB images for open-vocabulary 3D instance segmentation. We address this task by generating class-agnostic 3D masks for objects in the scene and associating them with text prompts. We observe that the projection of class-agnostic 3D point cloud instances already holds instance information; thus, using SAM might only result in redundancy that unnecessarily increases the inference time. We empirically find that a better performance of matching text prompts to 3D masks can be achieved in a faster fashion with a 2D object detector. We validate our Open-YOLO 3D on two benchmarks, ScanNet200 and Replica, under two scenarios: (i) with ground truth masks, where labels are required for given object proposals, and (ii) with class-agnostic 3D proposals generated from a 3D proposal network. Our Open-YOLO 3D achieves state-of-the-art performance on both datasets while obtaining up to sim16times speedup compared to the best existing method in literature. On ScanNet200 val. set, our Open-YOLO 3D achieves mean average precision (mAP) of 24.7\% while operating at 22 seconds per scene. Code and model are available at github.com/aminebdj/OpenYOLO3D.

It has been shown that traditional deep learning methods for electronic microscopy segmentation usually suffer from low transferability when samples and annotations are limited, while large-scale vision foundation models are more robust when transferring between different domains but facing sub-optimal improvement under fine-tuning. In this work, we present a new few-shot domain adaptation framework SAMDA, which combines the Segment Anything Model(SAM) with nnUNet in the embedding space to achieve high transferability and accuracy. Specifically, we choose the Unet-based network as the "expert" component to learn segmentation features efficiently and design a SAM-based adaptation module as the "generic" component for domain transfer. By amalgamating the "generic" and "expert" components, we mitigate the modality imbalance in the complex pre-training knowledge inherent to large-scale Vision Foundation models and the challenge of transferability inherent to traditional neural networks. The effectiveness of our model is evaluated on two electron microscopic image datasets with different modalities for mitochondria segmentation, which improves the dice coefficient on the target domain by 6.7%. Also, the SAM-based adaptor performs significantly better with only a single annotated image than the 10-shot domain adaptation on nnUNet. We further verify our model on four MRI datasets from different sources to prove its generalization ability.

In this work, we propose a novel approach, namely WeatherDG, that can generate realistic, weather-diverse, and driving-screen images based on the cooperation of two foundation models, i.e, Stable Diffusion (SD) and Large Language Model (LLM). Specifically, we first fine-tune the SD with source data, aligning the content and layout of generated samples with real-world driving scenarios. Then, we propose a procedural prompt generation method based on LLM, which can enrich scenario descriptions and help SD automatically generate more diverse, detailed images. In addition, we introduce a balanced generation strategy, which encourages the SD to generate high-quality objects of tailed classes under various weather conditions, such as riders and motorcycles. This segmentation-model-agnostic method can improve the generalization ability of existing models by additionally adapting them with the generated synthetic data. Experiments on three challenging datasets show that our method can significantly improve the segmentation performance of different state-of-the-art models on target domains. Notably, in the setting of ''Cityscapes to ACDC'', our method improves the baseline HRDA by 13.9% in mIoU.

Prompt engineering has shown remarkable success with large language models, yet its systematic exploration in computer vision remains limited. In semantic segmentation, both textual and visual prompts offer distinct advantages: textual prompts through open-vocabulary methods allow segmentation of arbitrary categories, while visual reference prompts provide intuitive reference examples. However, existing benchmarks evaluate these modalities in isolation, without direct comparison under identical conditions. We present Show or Tell (SoT), a novel benchmark specifically designed to evaluate both visual and textual prompts for semantic segmentation across 14 datasets spanning 7 diverse domains (common scenes, urban, food, waste, parts, tools, and land-cover). We evaluate 5 open-vocabulary methods and 4 visual reference prompt approaches, adapting the latter to handle multi-class segmentation through a confidence-based mask merging strategy. Our extensive experiments reveal that open-vocabulary methods excel with common concepts easily described by text but struggle with complex domains like tools, while visual reference prompt methods achieve good average results but exhibit high variability depending on the input prompt. Through comprehensive quantitative and qualitative analysis, we identify the strengths and weaknesses of both prompting modalities, providing valuable insights to guide future research in vision foundation models for segmentation tasks.

Accurate segmentation of regions of interest in biomedical images holds substantial value in image analysis. Although several foundation models for biomedical segmentation have currently achieved excellent performance on certain datasets, they typically demonstrate sub-optimal performance on unseen domain data. We owe the deficiency to lack of vision-language knowledge before segmentation. Multimodal Large Language Models (MLLMs) bring outstanding understanding and reasoning capabilities to multimodal tasks, which inspires us to leverage MLLMs to inject Vision-Language Knowledge (VLK), thereby enabling vision models to demonstrate superior generalization capabilities on cross-domain datasets. In this paper, we propose using MLLMs to guide SAM in learning microscopy crose-domain data, unifying Segment Anything in Microscopy, named uLLSAM. Specifically, we propose the Vision-Language Semantic Alignment (VLSA) module, which injects VLK into Segment Anything Model (SAM). We find that after SAM receives global VLK prompts, its performance improves significantly, but there are deficiencies in boundary contour perception. Therefore, we further propose Semantic Boundary Regularization (SBR) to prompt SAM. Our method achieves performance improvements of 7.71% in Dice and 12.10% in SA across 9 in-domain microscopy datasets, achieving state-of-the-art performance. Our method also demonstrates improvements of 6.79% in Dice and 10.08% in SA across 10 out-ofdomain datasets, exhibiting strong generalization capabilities. Code is available at https://github.com/ieellee/uLLSAM.

Visual foundation models have achieved remarkable results in zero-shot image classification and segmentation, but zero-shot change detection remains an open problem. In this paper, we propose the segment any change models (AnyChange), a new type of change detection model that supports zero-shot prediction and generalization on unseen change types and data distributions. AnyChange is built on the segment anything model (SAM) via our training-free adaptation method, bitemporal latent matching. By revealing and exploiting intra-image and inter-image semantic similarities in SAM's latent space, bitemporal latent matching endows SAM with zero-shot change detection capabilities in a training-free way. We also propose a point query mechanism to enable AnyChange's zero-shot object-centric change detection capability. We perform extensive experiments to confirm the effectiveness of AnyChange for zero-shot change detection. AnyChange sets a new record on the SECOND benchmark for unsupervised change detection, exceeding the previous SOTA by up to 4.4% F_1 score, and achieving comparable accuracy with negligible manual annotations (1 pixel per image) for supervised change detection.

Foundation models are a strong trend in deep learning and computer vision. These models serve as a base for applications as they require minor or no further fine-tuning by developers to integrate into their applications. Foundation models for zero-shot object segmentation such as Segment Anything (SAM) output segmentation masks from images without any further object information. When they are followed in a pipeline by an object identification model, they can perform object detection without training. Here, we focus on training such an object identification model. A crucial practical aspect for an object identification model is to be flexible in input size. As object identification is an image retrieval problem, a suitable method should handle multi-query multi-gallery situations without constraining the number of input images (e.g. by having fixed-size aggregation layers). The key solution to train such a model is the centroid triplet loss (CTL), which aggregates image features to their centroids. CTL yields high accuracy, avoids misleading training signals and keeps the model input size flexible. In our experiments, we establish a new state of the art on the ArmBench object identification task, which shows general applicability of our model. We furthermore demonstrate an integrated unseen object detection pipeline on the challenging HOPE dataset, which requires fine-grained detection. There, our pipeline matches and surpasses related methods which have been trained on dataset-specific data.

Foundation models have made significant strides in various applications, including text-to-image generation, panoptic segmentation, and natural language processing. This paper presents Instruct2Act, a framework that utilizes Large Language Models to map multi-modal instructions to sequential actions for robotic manipulation tasks. Specifically, Instruct2Act employs the LLM model to generate Python programs that constitute a comprehensive perception, planning, and action loop for robotic tasks. In the perception section, pre-defined APIs are used to access multiple foundation models where the Segment Anything Model (SAM) accurately locates candidate objects, and CLIP classifies them. In this way, the framework leverages the expertise of foundation models and robotic abilities to convert complex high-level instructions into precise policy codes. Our approach is adjustable and flexible in accommodating various instruction modalities and input types and catering to specific task demands. We validated the practicality and efficiency of our approach by assessing it on robotic tasks in different scenarios within tabletop manipulation domains. Furthermore, our zero-shot method outperformed many state-of-the-art learning-based policies in several tasks. The code for our proposed approach is available at https://github.com/OpenGVLab/Instruct2Act, serving as a robust benchmark for high-level robotic instruction tasks with assorted modality inputs.

Recent advancements in 2D and multimodal models have achieved remarkable success by leveraging large-scale training on extensive datasets. However, extending these achievements to enable free-form interactions and high-level semantic operations with complex 3D/4D scenes remains challenging. This difficulty stems from the limited availability of large-scale, annotated 3D/4D or multi-view datasets, which are crucial for generalizable vision and language tasks such as open-vocabulary and prompt-based segmentation, language-guided editing, and visual question answering (VQA). In this paper, we introduce Feature4X, a universal framework designed to extend any functionality from 2D vision foundation model into the 4D realm, using only monocular video input, which is widely available from user-generated content. The "X" in Feature4X represents its versatility, enabling any task through adaptable, model-conditioned 4D feature field distillation. At the core of our framework is a dynamic optimization strategy that unifies multiple model capabilities into a single representation. Additionally, to the best of our knowledge, Feature4X is the first method to distill and lift the features of video foundation models (e.g. SAM2, InternVideo2) into an explicit 4D feature field using Gaussian Splatting. Our experiments showcase novel view segment anything, geometric and appearance scene editing, and free-form VQA across all time steps, empowered by LLMs in feedback loops. These advancements broaden the scope of agentic AI applications by providing a foundation for scalable, contextually and spatiotemporally aware systems capable of immersive dynamic 4D scene interaction.

Medical image and video segmentation is a critical task for precision medicine, which has witnessed considerable progress in developing task or modality-specific and generalist models for 2D images. However, there have been limited studies on building general-purpose models for 3D images and videos with comprehensive user studies. Here, we present MedSAM2, a promptable segmentation foundation model for 3D image and video segmentation. The model is developed by fine-tuning the Segment Anything Model 2 on a large medical dataset with over 455,000 3D image-mask pairs and 76,000 frames, outperforming previous models across a wide range of organs, lesions, and imaging modalities. Furthermore, we implement a human-in-the-loop pipeline to facilitate the creation of large-scale datasets resulting in, to the best of our knowledge, the most extensive user study to date, involving the annotation of 5,000 CT lesions, 3,984 liver MRI lesions, and 251,550 echocardiogram video frames, demonstrating that MedSAM2 can reduce manual costs by more than 85%. MedSAM2 is also integrated into widely used platforms with user-friendly interfaces for local and cloud deployment, making it a practical tool for supporting efficient, scalable, and high-quality segmentation in both research and healthcare environments.

With the development of large language models, many remarkable linguistic systems like ChatGPT have thrived and achieved astonishing success on many tasks, showing the incredible power of foundation models. In the spirit of unleashing the capability of foundation models on vision tasks, the Segment Anything Model (SAM), a vision foundation model for image segmentation, has been proposed recently and presents strong zero-shot ability on many downstream 2D tasks. However, whether SAM can be adapted to 3D vision tasks has yet to be explored, especially 3D object detection. With this inspiration, we explore adapting the zero-shot ability of SAM to 3D object detection in this paper. We propose a SAM-powered BEV processing pipeline to detect objects and get promising results on the large-scale Waymo open dataset. As an early attempt, our method takes a step toward 3D object detection with vision foundation models and presents the opportunity to unleash their power on 3D vision tasks. The code is released at https://github.com/DYZhang09/SAM3D.

3D part segmentation is a crucial and challenging task in 3D perception, playing a vital role in applications such as robotics, 3D generation, and 3D editing. Recent methods harness the powerful Vision Language Models (VLMs) for 2D-to-3D knowledge distillation, achieving zero-shot 3D part segmentation. However, these methods are limited by their reliance on text prompts, which restricts the scalability to large-scale unlabeled datasets and the flexibility in handling part ambiguities. In this work, we introduce SAMPart3D, a scalable zero-shot 3D part segmentation framework that segments any 3D object into semantic parts at multiple granularities, without requiring predefined part label sets as text prompts. For scalability, we use text-agnostic vision foundation models to distill a 3D feature extraction backbone, allowing scaling to large unlabeled 3D datasets to learn rich 3D priors. For flexibility, we distill scale-conditioned part-aware 3D features for 3D part segmentation at multiple granularities. Once the segmented parts are obtained from the scale-conditioned part-aware 3D features, we use VLMs to assign semantic labels to each part based on the multi-view renderings. Compared to previous methods, our SAMPart3D can scale to the recent large-scale 3D object dataset Objaverse and handle complex, non-ordinary objects. Additionally, we contribute a new 3D part segmentation benchmark to address the lack of diversity and complexity of objects and parts in existing benchmarks. Experiments show that our SAMPart3D significantly outperforms existing zero-shot 3D part segmentation methods, and can facilitate various applications such as part-level editing and interactive segmentation.

We present a novel framework, i.e., Segment Any Anomaly + (SAA+), for zero-shot anomaly segmentation with hybrid prompt regularization to improve the adaptability of modern foundation models. Existing anomaly segmentation models typically rely on domain-specific fine-tuning, limiting their generalization across countless anomaly patterns. In this work, inspired by the great zero-shot generalization ability of foundation models like Segment Anything, we first explore their assembly to leverage diverse multi-modal prior knowledge for anomaly localization. For non-parameter foundation model adaptation to anomaly segmentation, we further introduce hybrid prompts derived from domain expert knowledge and target image context as regularization. Our proposed SAA+ model achieves state-of-the-art performance on several anomaly segmentation benchmarks, including VisA, MVTec-AD, MTD, and KSDD2, in the zero-shot setting. We will release the code at https://github.com/caoyunkang/Segment-Any-Anomaly{https://github.com/caoyunkang/Segment-Any-Anomaly}.

Do the rich representations of multi-modal diffusion transformers (DiTs) exhibit unique properties that enhance their interpretability? We introduce ConceptAttention, a novel method that leverages the expressive power of DiT attention layers to generate high-quality saliency maps that precisely locate textual concepts within images. Without requiring additional training, ConceptAttention repurposes the parameters of DiT attention layers to produce highly contextualized concept embeddings, contributing the major discovery that performing linear projections in the output space of DiT attention layers yields significantly sharper saliency maps compared to commonly used cross-attention mechanisms. Remarkably, ConceptAttention even achieves state-of-the-art performance on zero-shot image segmentation benchmarks, outperforming 11 other zero-shot interpretability methods on the ImageNet-Segmentation dataset and on a single-class subset of PascalVOC. Our work contributes the first evidence that the representations of multi-modal DiT models like Flux are highly transferable to vision tasks like segmentation, even outperforming multi-modal foundation models like CLIP.

We study open-world part segmentation in 3D: segmenting any part in any object based on any text query. Prior methods are limited in object categories and part vocabularies. Recent advances in AI have demonstrated effective open-world recognition capabilities in 2D. Inspired by this progress, we propose an open-world, direct-prediction model for 3D part segmentation that can be applied zero-shot to any object. Our approach, called Find3D, trains a general-category point embedding model on large-scale 3D assets from the internet without any human annotation. It combines a data engine, powered by foundation models for annotating data, with a contrastive training method. We achieve strong performance and generalization across multiple datasets, with up to a 3x improvement in mIoU over the next best method. Our model is 6x to over 300x faster than existing baselines. To encourage research in general-category open-world 3D part segmentation, we also release a benchmark for general objects and parts. Project website: https://ziqi-ma.github.io/find3dsite/

Current AI-assisted skin image diagnosis has achieved dermatologist-level performance in classifying skin cancer, driven by rapid advancements in deep learning architectures. However, unlike traditional vision tasks, skin images in general present unique challenges due to the limited availability of well-annotated datasets, complex variations in conditions, and the necessity for detailed interpretations to ensure patient safety. Previous segmentation methods have sought to reduce image noise and enhance diagnostic performance, but these techniques require fine-grained, pixel-level ground truth masks for training. In contrast, with the rise of foundation models, the Segment Anything Model (SAM) has been introduced to facilitate promptable segmentation, enabling the automation of the segmentation process with simple yet effective prompts. Efforts applying SAM predominantly focus on dermatoscopy images, which present more easily identifiable lesion boundaries than clinical photos taken with smartphones. This limitation constrains the practicality of these approaches to real-world applications. To overcome the challenges posed by noisy clinical photos acquired via non-standardized protocols and to improve diagnostic accessibility, we propose a novel Cross-Attentive Fusion framework for interpretable skin lesion diagnosis. Our method leverages SAM to generate visual concepts for skin diseases using prompts, integrating local visual concepts with global image features to enhance model performance. Extensive evaluation on two skin disease datasets demonstrates our proposed method's effectiveness on lesion diagnosis and interpretability.

Developing generalist foundation model has recently attracted tremendous attention among researchers in the field of AI for Medicine (AI4Medicine). A pivotal insight in developing these models is their reliance on dataset scaling, which emphasizes the requirements on developing open-source medical image datasets that incorporate diverse supervision signals across various imaging modalities. In this paper, we introduce RadGenome-Chest CT, a comprehensive, large-scale, region-guided 3D chest CT interpretation dataset based on CT-RATE. Specifically, we leverage the latest powerful universal segmentation and large language models, to extend the original datasets (over 25,692 non-contrast 3D chest CT volume and reports from 20,000 patients) from the following aspects: (i) organ-level segmentation masks covering 197 categories, which provide intermediate reasoning visual clues for interpretation; (ii) 665 K multi-granularity grounded reports, where each sentence of the report is linked to the corresponding anatomical region of CT volume in the form of a segmentation mask; (iii) 1.3 M grounded VQA pairs, where questions and answers are all linked with reference segmentation masks, enabling models to associate visual evidence with textual explanations. All grounded reports and VQA pairs in the validation set have gone through manual verification to ensure dataset quality. We believe that RadGenome-Chest CT can significantly advance the development of multimodal medical foundation models, by training to generate texts based on given segmentation regions, which is unattainable with previous relevant datasets. We will release all segmentation masks, grounded reports, and VQA pairs to facilitate further research and development in this field.

Few-shot segmentation is the problem of learning to identify specific types of objects (e.g., airplanes) in images from a small set of labeled reference images. The current state of the art is driven by resource-intensive construction of models for every new domain-specific application. Such models must be trained on enormous labeled datasets of unrelated objects (e.g., cars, trains, animals) so that their ``knowledge'' can be transferred to new types of objects. In this paper, we show how to leverage existing vision foundation models (VFMs) to reduce the incremental cost of creating few-shot segmentation models for new domains. Specifically, we introduce SAMIC, a small network that learns how to prompt VFMs in order to segment new types of objects in domain-specific applications. SAMIC enables any task to be approached as a few-shot learning problem. At 2.6 million parameters, it is 94% smaller than the leading models (e.g., having ResNet 101 backbone with 45+ million parameters). Even using 1/5th of the training data provided by one-shot benchmarks, SAMIC is competitive with, or sets the state of the art, on a variety of few-shot and semantic segmentation datasets including COCO-20^i, Pascal-5^i, PerSeg, FSS-1000, and NWPU VHR-10.

3D scene representations have gained immense popularity in recent years. Methods that use Neural Radiance fields are versatile for traditional tasks such as novel view synthesis. In recent times, some work has emerged that aims to extend the functionality of NeRF beyond view synthesis, for semantically aware tasks such as editing and segmentation using 3D feature field distillation from 2D foundation models. However, these methods have two major limitations: (a) they are limited by the rendering speed of NeRF pipelines, and (b) implicitly represented feature fields suffer from continuity artifacts reducing feature quality. Recently, 3D Gaussian Splatting has shown state-of-the-art performance on real-time radiance field rendering. In this work, we go one step further: in addition to radiance field rendering, we enable 3D Gaussian splatting on arbitrary-dimension semantic features via 2D foundation model distillation. This translation is not straightforward: naively incorporating feature fields in the 3DGS framework leads to warp-level divergence. We propose architectural and training changes to efficiently avert this problem. Our proposed method is general, and our experiments showcase novel view semantic segmentation, language-guided editing and segment anything through learning feature fields from state-of-the-art 2D foundation models such as SAM and CLIP-LSeg. Across experiments, our distillation method is able to provide comparable or better results, while being significantly faster to both train and render. Additionally, to the best of our knowledge, we are the first method to enable point and bounding-box prompting for radiance field manipulation, by leveraging the SAM model. Project website at: https://feature-3dgs.github.io/

Humans can develop internal world models that encode common sense knowledge, telling them how the world works and predicting the consequences of their actions. This concept has emerged as a promising direction for establishing general-purpose machine-learning models in recent preliminary works, e.g., for visual representation learning. In this paper, we present CheXWorld, the first effort towards a self-supervised world model for radiographic images. Specifically, our work develops a unified framework that simultaneously models three aspects of medical knowledge essential for qualified radiologists, including 1) local anatomical structures describing the fine-grained characteristics of local tissues (e.g., architectures, shapes, and textures); 2) global anatomical layouts describing the global organization of the human body (e.g., layouts of organs and skeletons); and 3) domain variations that encourage CheXWorld to model the transitions across different appearance domains of radiographs (e.g., varying clarity, contrast, and exposure caused by collecting radiographs from different hospitals, devices, or patients). Empirically, we design tailored qualitative and quantitative analyses, revealing that CheXWorld successfully captures these three dimensions of medical knowledge. Furthermore, transfer learning experiments across eight medical image classification and segmentation benchmarks showcase that CheXWorld significantly outperforms existing SSL methods and large-scale medical foundation models. Code & pre-trained models are available at https://github.com/LeapLabTHU/CheXWorld.

Accurately detecting and classifying damage in analogue media such as paintings, photographs, textiles, mosaics, and frescoes is essential for cultural heritage preservation. While machine learning models excel in correcting degradation if the damage operator is known a priori, we show that they fail to robustly predict where the damage is even after supervised training; thus, reliable damage detection remains a challenge. Motivated by this, we introduce ARTeFACT, a dataset for damage detection in diverse types analogue media, with over 11,000 annotations covering 15 kinds of damage across various subjects, media, and historical provenance. Furthermore, we contribute human-verified text prompts describing the semantic contents of the images, and derive additional textual descriptions of the annotated damage. We evaluate CNN, Transformer, diffusion-based segmentation models, and foundation vision models in zero-shot, supervised, unsupervised and text-guided settings, revealing their limitations in generalising across media types. Our dataset is available at https://daniela997.github.io/ARTeFACT/{https://daniela997.github.io/ARTeFACT/} as the first-of-its-kind benchmark for analogue media damage detection and restoration.

In this work, we show that synthetic data created by generative models is complementary to computer graphics (CG) rendered data for achieving remarkable generalization performance on diverse real-world scenes for 3D human pose and shape estimation (HPS). Specifically, we propose an effective approach based on recent diffusion models, termed HumanWild, which can effortlessly generate human images and corresponding 3D mesh annotations. We first collect a large-scale human-centric dataset with comprehensive annotations, e.g., text captions and surface normal images. Then, we train a customized ControlNet model upon this dataset to generate diverse human images and initial ground-truth labels. At the core of this step is that we can easily obtain numerous surface normal images from a 3D human parametric model, e.g., SMPL-X, by rendering the 3D mesh onto the image plane. As there exists inevitable noise in the initial labels, we then apply an off-the-shelf foundation segmentation model, i.e., SAM, to filter negative data samples. Our data generation pipeline is flexible and customizable to facilitate different real-world tasks, e.g., ego-centric scenes and perspective-distortion scenes. The generated dataset comprises 0.79M images with corresponding 3D annotations, covering versatile viewpoints, scenes, and human identities. We train various HPS regressors on top of the generated data and evaluate them on a wide range of benchmarks (3DPW, RICH, EgoBody, AGORA, SSP-3D) to verify the effectiveness of the generated data. By exclusively employing generative models, we generate large-scale in-the-wild human images and high-quality annotations, eliminating the need for real-world data collection.

Medical image segmentation allows quantifying target structure size and shape, aiding in disease diagnosis, prognosis, surgery planning, and comprehension.Building upon recent advancements in foundation Vision-Language Models (VLMs) from natural image-text pairs, several studies have proposed adapting them to Vision-Language Segmentation Models (VLSMs) that allow using language text as an additional input to segmentation models. Introducing auxiliary information via text with human-in-the-loop prompting during inference opens up unique opportunities, such as open vocabulary segmentation and potentially more robust segmentation models against out-of-distribution data. Although transfer learning from natural to medical images has been explored for image-only segmentation models, the joint representation of vision-language in segmentation problems remains underexplored. This study introduces the first systematic study on transferring VLSMs to 2D medical images, using carefully curated 11 datasets encompassing diverse modalities and insightful language prompts and experiments. Our findings demonstrate that although VLSMs show competitive performance compared to image-only models for segmentation after finetuning in limited medical image datasets, not all VLSMs utilize the additional information from language prompts, with image features playing a dominant role. While VLSMs exhibit enhanced performance in handling pooled datasets with diverse modalities and show potential robustness to domain shifts compared to conventional segmentation models, our results suggest that novel approaches are required to enable VLSMs to leverage the various auxiliary information available through language prompts. The code and datasets are available at https://github.com/naamiinepal/medvlsm.

In studies of transferable learning, scaling laws are obtained for various important foundation models to predict their properties and performance at larger scales. We show here how scaling law derivation can also be used for model and dataset comparison, allowing to decide which procedure is to be preferred for pre-training. For the first time, full scaling laws based on dense measurements across a wide span of model and samples seen scales are derived for two important language-vision learning procedures, CLIP and MaMMUT, that use either contrastive only or contrastive and captioning text generative loss. Ensuring sufficient prediction accuracy for held out points, we use derived scaling laws to compare both models, obtaining evidence for MaMMUT's stronger improvement with scale and better sample efficiency than standard CLIP. To strengthen validity of the comparison, we show scaling laws for various downstream tasks, classification, retrieval, and segmentation, and for different open datasets, DataComp, DFN and Re-LAION, observing consistently the same trends. We show that comparison can also be performed when deriving scaling laws with a constant learning rate schedule, reducing compute cost. Accurate derivation of scaling laws provides thus means to perform model and dataset comparison across scale spans, avoiding misleading conclusions based on measurements from single reference scales only, paving the road for systematic comparison and improvement of open foundation models and datasets for their creation. We release all the pre-trained models with their intermediate checkpoints, including openMaMMUT-L/14, which achieves 80.3% zero-shot ImageNet-1k accuracy, trained on 12.8B samples from DataComp-1.4B. Code for reproducing experiments in the paper and raw experiments data can be found at https://github.com/LAION-AI/scaling-laws-for-comparison.

Foundation Vision-Language Models (VLMs) trained using large-scale open-domain images and text pairs have recently been adapted to develop Vision-Language Segmentation Models (VLSMs) that allow providing text prompts during inference to guide image segmentation. If robust and powerful VLSMs can be built for medical images, it could aid medical professionals in many clinical tasks where they must spend substantial time delineating the target structure of interest. VLSMs for medical images resort to fine-tuning base VLM or VLSM pretrained on open-domain natural image datasets due to fewer annotated medical image datasets; this fine-tuning is resource-consuming and expensive as it usually requires updating all or a significant fraction of the pretrained parameters. Recently, lightweight blocks called adapters have been proposed in VLMs that keep the pretrained model frozen and only train adapters during fine-tuning, substantially reducing the computing resources required. We introduce a novel adapter, VLSM-Adapter, that can fine-tune pretrained vision-language segmentation models using transformer encoders. Our experiments in widely used CLIP-based segmentation models show that with only 3 million trainable parameters, the VLSM-Adapter outperforms state-of-the-art and is comparable to the upper bound end-to-end fine-tuning. The source code is available at: https://github.com/naamiinepal/vlsm-adapter.

We tackle open-vocabulary 3D scene understanding by introducing a novel data generation pipeline and training framework. Our method addresses three critical requirements for effective training: precise 3D region segmentation, comprehensive textual descriptions, and sufficient dataset scale. By leveraging state-of-the-art open-vocabulary image segmentation models and region-aware Vision-Language Models, we develop an automatic pipeline that generates high-quality 3D mask-text pairs. Applying this pipeline to multiple 3D scene datasets, we create Mosaic3D-5.6M, a dataset of over 30K annotated scenes with 5.6M mask-text pairs, significantly larger than existing datasets. Building upon this data, we propose Mosaic3D, a foundation model combining a 3D encoder trained with contrastive learning and a lightweight mask decoder for open-vocabulary 3D semantic and instance segmentation. Our approach achieves state-of-the-art results on open-vocabulary 3D semantic and instance segmentation tasks including ScanNet200, Matterport3D, and ScanNet++, with ablation studies validating the effectiveness of our large-scale training data.

We present Sapiens, a family of models for four fundamental human-centric vision tasks - 2D pose estimation, body-part segmentation, depth estimation, and surface normal prediction. Our models natively support 1K high-resolution inference and are extremely easy to adapt for individual tasks by simply fine-tuning models pretrained on over 300 million in-the-wild human images. We observe that, given the same computational budget, self-supervised pretraining on a curated dataset of human images significantly boosts the performance for a diverse set of human-centric tasks. The resulting models exhibit remarkable generalization to in-the-wild data, even when labeled data is scarce or entirely synthetic. Our simple model design also brings scalability - model performance across tasks improves as we scale the number of parameters from 0.3 to 2 billion. Sapiens consistently surpasses existing baselines across various human-centric benchmarks. We achieve significant improvements over the prior state-of-the-art on Humans-5K (pose) by 7.6 mAP, Humans-2K (part-seg) by 17.1 mIoU, Hi4D (depth) by 22.4% relative RMSE, and THuman2 (normal) by 53.5% relative angular error.

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of generalizability, and the necessity to incorporate multi-modal data effectively. A foundation model, which is a large-scale pre-trained AI model, offers a versatile base that can be adapted to a variety of specific tasks and contexts. Here, we present a novel foundation model, VISION-MAE, specifically designed for medical imaging. Specifically, VISION-MAE is trained on a dataset of 2.5 million unlabeled images from various modalities (CT, MR, PET, X-rays, and ultrasound), using self-supervised learning techniques. It is then adapted to classification and segmentation tasks using explicit labels. VISION-MAE has high label efficiency, outperforming several benchmark models in both in-domain and out-of-domain applications, and achieves high performance even with reduced availability of labeled data. This model represents a significant advancement in medical imaging AI, offering a generalizable and robust solution for improving segmentation and classification tasks while reducing the data annotation workload.

This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates an initial coarse segmentation mask using the ALPnet prototypical network, augmented with a DINOv2 encoder. Following the extraction of an initial mask, prompts are extracted, such as points and bounding boxes, which are then input into the Segment Anything Model (SAM). State-of-the-art results are shown on several medical image datasets and demonstrate automated segmentation capabilities using a single image example (one shot) with no need for fine-tuning of the foundation model. Our code is available at: https://github.com/levayz/ProtoSAM

Large-scale vision foundation models have made significant progress in visual tasks on natural images, with vision transformers being the primary choice due to their good scalability and representation ability. However, large-scale models in remote sensing (RS) have not yet been sufficiently explored. In this paper, we resort to plain vision transformers with about 100 million parameters and make the first attempt to propose large vision models tailored to RS tasks and investigate how such large models perform. To handle the large sizes and objects of arbitrary orientations in RS images, we propose a new rotated varied-size window attention to replace the original full attention in transformers, which can significantly reduce the computational cost and memory footprint while learning better object representation by extracting rich context from the generated diverse windows. Experiments on detection tasks show the superiority of our model over all state-of-the-art models, achieving 81.24% mAP on the DOTA-V1.0 dataset. The results of our models on downstream classification and segmentation tasks also show competitive performance compared to existing advanced methods. Further experiments show the advantages of our models in terms of computational complexity and data efficiency in transferring.

The foundation model has recently garnered significant attention due to its potential to revolutionize the field of visual representation learning in a self-supervised manner. While most foundation models are tailored to effectively process RGB images for various visual tasks, there is a noticeable gap in research focused on spectral data, which offers valuable information for scene understanding, especially in remote sensing (RS) applications. To fill this gap, we created for the first time a universal RS foundation model, named SpectralGPT, which is purpose-built to handle spectral RS images using a novel 3D generative pretrained transformer (GPT). Compared to existing foundation models, SpectralGPT 1) accommodates input images with varying sizes, resolutions, time series, and regions in a progressive training fashion, enabling full utilization of extensive RS big data; 2) leverages 3D token generation for spatial-spectral coupling; 3) captures spectrally sequential patterns via multi-target reconstruction; 4) trains on one million spectral RS images, yielding models with over 600 million parameters. Our evaluation highlights significant performance improvements with pretrained SpectralGPT models, signifying substantial potential in advancing spectral RS big data applications within the field of geoscience across four downstream tasks: single/multi-label scene classification, semantic segmentation, and change detection.

Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing models tend to underperform on independent, unseen data. Foundation models (FMs), large AI models trained on vast unlabeled datasets, have shown promise in overcoming these challenges. Nonetheless, available FMs for ophthalmology lack extensive validation, especially for segmentation tasks, and focus on a single imaging modality. In this context, we propose MIRAGE, a novel multimodal FM for the analysis of OCT and scanning laser ophthalmoscopy (SLO) images. Additionally, we propose a new evaluation benchmark with OCT/SLO classification and segmentation tasks. The comparison with general and specialized FMs and segmentation methods shows the superiority of MIRAGE in both types of tasks, highlighting its suitability as a basis for the development of robust AI systems for retinal OCT image analysis. Both MIRAGE and the evaluation benchmark are publicly available: https://github.com/j-morano/MIRAGE.

Zero- and few-shot visual anomaly segmentation relies on powerful vision-language models that detect unseen anomalies using manually designed textual prompts. However, visual representations are inherently independent of language. In this paper, we explore the potential of a pure visual foundation model as an alternative to widely used vision-language models for universal visual anomaly segmentation. We present a novel paradigm that unifies anomaly segmentation into change segmentation. This paradigm enables us to leverage large-scale synthetic image pairs, featuring object-level and local region changes, derived from existing image datasets, which are independent of target anomaly datasets. We propose a one-prompt Meta-learning framework for Universal Anomaly Segmentation (MetaUAS) that is trained on this synthetic dataset and then generalizes well to segment any novel or unseen visual anomalies in the real world. To handle geometrical variations between prompt and query images, we propose a soft feature alignment module that bridges paired-image change perception and single-image semantic segmentation. This is the first work to achieve universal anomaly segmentation using a pure vision model without relying on special anomaly detection datasets and pre-trained visual-language models. Our method effectively and efficiently segments any anomalies with only one normal image prompt and enjoys training-free without guidance from language. Our MetaUAS significantly outperforms previous zero-shot, few-shot, and even full-shot anomaly segmentation methods. The code and pre-trained models are available at https://github.com/gaobb/MetaUAS.

Multi-modal interpretation of biomedical images opens up novel opportunities in biomedical image analysis. Conventional AI approaches typically rely on disjointed training, i.e., Large Language Models (LLMs) for clinical text generation and segmentation models for target extraction, which results in inflexible real-world deployment and a failure to leverage holistic biomedical information. To this end, we introduce UniBiomed, the first universal foundation model for grounded biomedical image interpretation. UniBiomed is based on a novel integration of Multi-modal Large Language Model (MLLM) and Segment Anything Model (SAM), which effectively unifies the generation of clinical texts and the segmentation of corresponding biomedical objects for grounded interpretation. In this way, UniBiomed is capable of tackling a wide range of biomedical tasks across ten diverse biomedical imaging modalities. To develop UniBiomed, we curate a large-scale dataset comprising over 27 million triplets of images, annotations, and text descriptions across ten imaging modalities. Extensive validation on 84 internal and external datasets demonstrated that UniBiomed achieves state-of-the-art performance in segmentation, disease recognition, region-aware diagnosis, visual question answering, and report generation. Moreover, unlike previous models that rely on clinical experts to pre-diagnose images and manually craft precise textual or visual prompts, UniBiomed can provide automated and end-to-end grounded interpretation for biomedical image analysis. This represents a novel paradigm shift in clinical workflows, which will significantly improve diagnostic efficiency. In summary, UniBiomed represents a novel breakthrough in biomedical AI, unlocking powerful grounded interpretation capabilities for more accurate and efficient biomedical image analysis.

Modern Earth observation (EO) increasingly leverages deep learning to harness the scale and diversity of satellite imagery across sensors and regions. While recent foundation models have demonstrated promising generalization across EO tasks, many remain limited by the scale, geographical coverage, and spectral diversity of their training data, factors critical for learning globally transferable representations. In this work, we introduce TerraFM, a scalable self-supervised learning model that leverages globally distributed Sentinel-1 and Sentinel-2 imagery, combined with large spatial tiles and land-cover aware sampling to enrich spatial and semantic coverage. By treating sensing modalities as natural augmentations in our self-supervised approach, we unify radar and optical inputs via modality-specific patch embeddings and adaptive cross-attention fusion. Our training strategy integrates local-global contrastive learning and introduces a dual-centering mechanism that incorporates class-frequency-aware regularization to address long-tailed distributions in land cover.TerraFM achieves strong generalization on both classification and segmentation tasks, outperforming prior models on GEO-Bench and Copernicus-Bench. Our code and pretrained models are publicly available at: https://github.com/mbzuai-oryx/TerraFM .

Segment Anything Model (SAM) has demonstrated impressive performance on a wide range of natural image segmentation tasks. However, its performance significantly deteriorates when directly applied to medical domain, due to the remarkable differences between natural images and medical images. Some researchers have attempted to train SAM on large scale medical datasets. However, poor zero-shot performance is observed from the experimental results. In this context, inspired by the superior performance of U-Net-like models in medical image segmentation, we propose SAMUNet, a new foundation model which incorporates U-Net to the original SAM, to fully leverage the powerful contextual modeling ability of convolutions. To be specific, we parallel a convolutional branch in the image encoder, which is trained independently with the vision Transformer branch frozen. Additionally, we employ multi-scale fusion in the mask decoder, to facilitate accurate segmentation of objects with different scales. We train SAM-UNet on SA-Med2D-16M, the largest 2-dimensional medical image segmentation dataset to date, yielding a universal pretrained model for medical images. Extensive experiments are conducted to evaluate the performance of the model, and state-of-the-art result is achieved, with a dice similarity coefficient score of 0.883 on SA-Med2D-16M dataset. Specifically, in zero-shot segmentation experiments, our model not only significantly outperforms previous large medical SAM models across all modalities, but also substantially mitigates the performance degradation seen on unseen modalities. It should be highlighted that SAM-UNet is an efficient and extensible foundation model, which can be further fine-tuned for other downstream tasks in medical community. The code is available at https://github.com/Hhankyangg/sam-unet.

Fine urban change segmentation using multi-temporal remote sensing images is essential for understanding human-environment interactions in urban areas. Although there have been advances in high-quality land cover datasets that reveal the physical features of urban landscapes, the lack of fine-grained land use datasets hinders a deeper understanding of how human activities are distributed across the landscape and the impact of these activities on the environment, thus constraining proper technique development. To address this, we introduce FUSU, the first fine-grained land use change segmentation dataset for Fine-grained Urban Semantic Understanding. FUSU features the most detailed land use classification system to date, with 17 classes and 30 billion pixels of annotations. It includes bi-temporal high-resolution satellite images with 0.2-0.5 m ground sample distance and monthly optical and radar satellite time series, covering 847 km^2 across five urban areas in the southern and northern of China with different geographical features. The fine-grained land use pixel-wise annotations and high spatial-temporal resolution data provide a robust foundation for developing proper deep learning models to provide contextual insights on human activities and urbanization. To fully leverage FUSU, we propose a unified time-series architecture for both change detection and segmentation. We benchmark FUSU on various methods for several tasks. Dataset and code are available at: https://github.com/yuanshuai0914/FUSU.

Artificial intelligence-assisted imaging analysis has made substantial strides in tumor diagnosis and management. Here we present PASTA, a pan-tumor CT foundation model that achieves state-of-the-art performance on 45 of 46 representative oncology tasks -- including lesion segmentation, tumor detection in plain CT, tumor staging, survival prediction, structured report generation, and cross-modality transfer learning, significantly outperforming the second-best models on 35 tasks. This remarkable advancement is driven by our development of PASTA-Gen, an innovative synthetic tumor generation framework that produces a comprehensive dataset of 30,000 CT scans with pixel-level annotated lesions and paired structured reports, encompassing malignancies across ten organs and five benign lesion types. By leveraging this rich, high-quality synthetic data, we overcome a longstanding bottleneck in the development of CT foundation models -- specifically, the scarcity of publicly available, high-quality annotated datasets due to privacy constraints and the substantial labor required for scaling precise data annotation. Encouragingly, PASTA demonstrates exceptional data efficiency with promising practical value, markedly improving performance on various tasks with only a small amount of real-world data. The open release of both the synthetic dataset and PASTA foundation model effectively addresses the challenge of data scarcity, thereby advancing oncological research and clinical translation.

Medical image segmentation and video object segmentation are essential for diagnosing and analyzing diseases by identifying and measuring biological structures. Recent advances in natural domain have been driven by foundation models like the Segment Anything Model 2 (SAM 2). To explore the performance of SAM 2 in biomedical applications, we designed two evaluation pipelines for single-frame image segmentation and multi-frame video segmentation with varied prompt designs, revealing SAM 2's limitations in medical contexts. Consequently, we developed BioSAM 2, an enhanced foundation model optimized for biomedical data based on SAM 2. Our experiments show that BioSAM 2 not only surpasses the performance of existing state-of-the-art foundation models but also matches or even exceeds specialist models, demonstrating its efficacy and potential in the medical domain.

The recent segmentation foundation model, Segment Anything Model (SAM), exhibits strong zero-shot segmentation capabilities, but it falls short in generating fine-grained precise masks. To address this limitation, we propose a novel zero-shot image matting model, called ZIM, with two key contributions: First, we develop a label converter that transforms segmentation labels into detailed matte labels, constructing the new SA1B-Matte dataset without costly manual annotations. Training SAM with this dataset enables it to generate precise matte masks while maintaining its zero-shot capability. Second, we design the zero-shot matting model equipped with a hierarchical pixel decoder to enhance mask representation, along with a prompt-aware masked attention mechanism to improve performance by enabling the model to focus on regions specified by visual prompts. We evaluate ZIM using the newly introduced MicroMat-3K test set, which contains high-quality micro-level matte labels. Experimental results show that ZIM outperforms existing methods in fine-grained mask generation and zero-shot generalization. Furthermore, we demonstrate the versatility of ZIM in various downstream tasks requiring precise masks, such as image inpainting and 3D NeRF. Our contributions provide a robust foundation for advancing zero-shot matting and its downstream applications across a wide range of computer vision tasks. The code is available at https://github.com/naver-ai/ZIM.

Interactive 3D segmentation in radiance fields is an appealing task since its importance in 3D scene understanding and manipulation. However, existing methods face challenges in either achieving fine-grained, multi-granularity segmentation or contending with substantial computational overhead, inhibiting real-time interaction. In this paper, we introduce Segment Any 3D GAussians (SAGA), a novel 3D interactive segmentation approach that seamlessly blends a 2D segmentation foundation model with 3D Gaussian Splatting (3DGS), a recent breakthrough of radiance fields. SAGA efficiently embeds multi-granularity 2D segmentation results generated by the segmentation foundation model into 3D Gaussian point features through well-designed contrastive training. Evaluation on existing benchmarks demonstrates that SAGA can achieve competitive performance with state-of-the-art methods. Moreover, SAGA achieves multi-granularity segmentation and accommodates various prompts, including points, scribbles, and 2D masks. Notably, SAGA can finish the 3D segmentation within milliseconds, achieving nearly 1000x acceleration compared to previous SOTA. The project page is at https://jumpat.github.io/SAGA.

Single image reflection removal is inherently ambiguous, as both the reflection and transmission components requiring separation may follow natural image statistics. Existing methods attempt to address the issue by using various types of low-level and physics-based cues as sources of reflection signals. However, these cues are not universally applicable, since they are only observable in specific capture scenarios. This leads to a significant performance drop when test images do not align with their assumptions. In this paper, we aim to explore a novel flexible interactive reflection removal approach that leverages various forms of sparse human guidance, such as points and bounding boxes, as auxiliary high-level prior to achieve robust reflection removal. However, incorporating the raw user guidance naively into the existing reflection removal network does not result in performance gains. To this end, we innovatively transform raw user input into a unified form -- reflection masks using an Interactive Segmentation Foundation Model. Such a design absorbs the quintessence of the foundational segmentation model and flexible human guidance, thereby mitigating the challenges of reflection separations. Furthermore, to fully utilize user guidance and reduce user annotation costs, we design a mask-guided reflection removal network, comprising our proposed self-adaptive prompt block. This block adaptively incorporates user guidance as anchors and refines transmission features via cross-attention mechanisms. Extensive results on real-world images validate that our method demonstrates state-of-the-art performance on various datasets with the help of flexible and sparse user guidance. Our code and dataset will be publicly available here https://github.com/ShawnChenn/FlexibleReflectionRemoval.

Interactive Medical Image Segmentation (IMIS) has long been constrained by the limited availability of large-scale, diverse, and densely annotated datasets, which hinders model generalization and consistent evaluation across different models. In this paper, we introduce the IMed-361M benchmark dataset, a significant advancement in general IMIS research. First, we collect and standardize over 6.4 million medical images and their corresponding ground truth masks from multiple data sources. Then, leveraging the strong object recognition capabilities of a vision foundational model, we automatically generated dense interactive masks for each image and ensured their quality through rigorous quality control and granularity management. Unlike previous datasets, which are limited by specific modalities or sparse annotations, IMed-361M spans 14 modalities and 204 segmentation targets, totaling 361 million masks-an average of 56 masks per image. Finally, we developed an IMIS baseline network on this dataset that supports high-quality mask generation through interactive inputs, including clicks, bounding boxes, text prompts, and their combinations. We evaluate its performance on medical image segmentation tasks from multiple perspectives, demonstrating superior accuracy and scalability compared to existing interactive segmentation models. To facilitate research on foundational models in medical computer vision, we release the IMed-361M and model at https://github.com/uni-medical/IMIS-Bench.

Precise image segmentation provides clinical study with meaningful and well-structured information. Despite the remarkable progress achieved in medical image segmentation, there is still an absence of foundation segmentation model that can segment a wide range of anatomical categories with easy user interaction. In this paper, we propose a universal and interactive volumetric medical image segmentation model, named SegVol. By training on 90k unlabeled Computed Tomography (CT) volumes and 6k labeled CTs, this foundation model supports the segmentation of over 200 anatomical categories using semantic and spatial prompts. Extensive experiments verify that SegVol outperforms the state of the art by a large margin on multiple segmentation benchmarks. Notably, on three challenging lesion datasets, our method achieves around 20% higher Dice score than nnU-Net. The model and data are publicly available at: https://github.com/BAAI-DCAI/SegVol.

Visual-inertial odometry (VIO) is widely used in various fields, such as robots, drones, and autonomous vehicles, due to its low cost and complementary sensors. Most VIO methods presuppose that observed objects are static and time-invariant. However, real-world scenes often feature dynamic objects, compromising the accuracy of pose estimation. These moving entities include cars, trucks, buses, motorcycles, and pedestrians. The diversity and partial occlusion of these objects present a tough challenge for existing dynamic object removal techniques. To tackle this challenge, we introduce GMS-VINS, which integrates an enhanced SORT algorithm along with a robust multi-category segmentation framework into VIO, thereby improving pose estimation accuracy in environments with diverse dynamic objects and frequent occlusions. Leveraging the promptable foundation model, our solution efficiently tracks and segments a wide range of object categories. The enhanced SORT algorithm significantly improves the reliability of tracking multiple dynamic objects, especially in urban settings with partial occlusions or swift movements. We evaluated our proposed method using multiple public datasets representing various scenes, as well as in a real-world scenario involving diverse dynamic objects. The experimental results demonstrate that our proposed method performs impressively in multiple scenarios, outperforming other state-of-the-art methods. This highlights its remarkable generalization and adaptability in diverse dynamic environments, showcasing its potential to handle various dynamic objects in practical applications.

Leveraging vast training data (SA-1B), the foundation Segment Anything Model (SAM) proposed by Meta AI Research exhibits remarkable generalization and zero-shot capabilities. Nonetheless, as a category-agnostic instance segmentation method, SAM heavily depends on prior manual guidance involving points, boxes, and coarse-grained masks. Additionally, its performance on remote sensing image segmentation tasks has yet to be fully explored and demonstrated. In this paper, we consider designing an automated instance segmentation approach for remote sensing images based on the SAM foundation model, incorporating semantic category information. Inspired by prompt learning, we propose a method to learn the generation of appropriate prompts for SAM input. This enables SAM to produce semantically discernible segmentation results for remote sensing images, which we refer to as RSPrompter. We also suggest several ongoing derivatives for instance segmentation tasks, based on recent developments in the SAM community, and compare their performance with RSPrompter. Extensive experimental results on the WHU building, NWPU VHR-10, and SSDD datasets validate the efficacy of our proposed method. Our code is accessible at https://kyanchen.github.io/RSPrompter.

The detection and classification of exfoliated two-dimensional (2D) material flakes from optical microscope images can be automated using computer vision algorithms. This has the potential to increase the accuracy and objectivity of classification and the efficiency of sample fabrication, and it allows for large-scale data collection. Existing algorithms often exhibit challenges in identifying low-contrast materials and typically require large amounts of training data. Here, we present a deep learning model, called MaskTerial, that uses an instance segmentation network to reliably identify 2D material flakes. The model is extensively pre-trained using a synthetic data generator, that generates realistic microscopy images from unlabeled data. This results in a model that can to quickly adapt to new materials with as little as 5 to 10 images. Furthermore, an uncertainty estimation model is used to finally classify the predictions based on optical contrast. We evaluate our method on eight different datasets comprising five different 2D materials and demonstrate significant improvements over existing techniques in the detection of low-contrast materials such as hexagonal boron nitride.

The digitization of histology slides has revolutionized pathology, providing massive datasets for cancer diagnosis and research. Contrastive self-supervised and vision-language models have been shown to effectively mine large pathology datasets to learn discriminative representations. On the other hand, generative models, capable of synthesizing realistic and diverse images, present a compelling solution to address unique problems in pathology that involve synthesizing images; overcoming annotated data scarcity, enabling privacy-preserving data sharing, and performing inherently generative tasks, such as virtual staining. We introduce PixCell, the first diffusion-based generative foundation model for histopathology. We train PixCell on PanCan-30M, a vast, diverse dataset derived from 69,184 H\&E-stained whole slide images covering various cancer types. We employ a progressive training strategy and a self-supervision-based conditioning that allows us to scale up training without any annotated data. PixCell generates diverse and high-quality images across multiple cancer types, which we find can be used in place of real data to train a self-supervised discriminative model. Synthetic images shared between institutions are subject to fewer regulatory barriers than would be the case with real clinical images. Furthermore, we showcase the ability to precisely control image generation using a small set of annotated images, which can be used for both data augmentation and educational purposes. Testing on a cell segmentation task, a mask-guided PixCell enables targeted data augmentation, improving downstream performance. Finally, we demonstrate PixCell's ability to use H\&E structural staining to infer results from molecular marker studies; we use this capability to infer IHC staining from H\&E images. Our trained models are publicly released to accelerate research in computational pathology.

Biomedical image analysis is fundamental for biomedical discovery in cell biology, pathology, radiology, and many other biomedical domains. Holistic image analysis comprises interdependent subtasks such as segmentation, detection, and recognition of relevant objects. Here, we propose BiomedParse, a biomedical foundation model for imaging parsing that can jointly conduct segmentation, detection, and recognition for 82 object types across 9 imaging modalities. Through joint learning, we can improve accuracy for individual tasks and enable novel applications such as segmenting all relevant objects in an image through a text prompt, rather than requiring users to laboriously specify the bounding box for each object. We leveraged readily available natural-language labels or descriptions accompanying those datasets and use GPT-4 to harmonize the noisy, unstructured text information with established biomedical object ontologies. We created a large dataset comprising over six million triples of image, segmentation mask, and textual description. On image segmentation, we showed that BiomedParse is broadly applicable, outperforming state-of-the-art methods on 102,855 test image-mask-label triples across 9 imaging modalities (everything). On object detection, which aims to locate a specific object of interest, BiomedParse again attained state-of-the-art performance, especially on objects with irregular shapes (everywhere). On object recognition, which aims to identify all objects in a given image along with their semantic types, we showed that BiomedParse can simultaneously segment and label all biomedical objects in an image (all at once). In summary, BiomedParse is an all-in-one tool for biomedical image analysis by jointly solving segmentation, detection, and recognition for all major biomedical image modalities, paving the path for efficient and accurate image-based biomedical discovery.

The Segment Anything Model 2 (SAM 2) is the latest generation foundation model for image and video segmentation. Trained on the expansive Segment Anything Video (SA-V) dataset, which comprises 35.5 million masks across 50.9K videos, SAM 2 advances its predecessor's capabilities by supporting zero-shot segmentation through various prompts (e.g., points, boxes, and masks). Its robust zero-shot performance and efficient memory usage make SAM 2 particularly appealing for surgical tool segmentation in videos, especially given the scarcity of labeled data and the diversity of surgical procedures. In this study, we evaluate the zero-shot video segmentation performance of the SAM 2 model across different types of surgeries, including endoscopy and microscopy. We also assess its performance on videos featuring single and multiple tools of varying lengths to demonstrate SAM 2's applicability and effectiveness in the surgical domain. We found that: 1) SAM 2 demonstrates a strong capability for segmenting various surgical videos; 2) When new tools enter the scene, additional prompts are necessary to maintain segmentation accuracy; and 3) Specific challenges inherent to surgical videos can impact the robustness of SAM 2.

We present GLEE in this work, an object-level foundation model for locating and identifying objects in images and videos. Through a unified framework, GLEE accomplishes detection, segmentation, tracking, grounding, and identification of arbitrary objects in the open world scenario for various object perception tasks. Adopting a cohesive learning strategy, GLEE acquires knowledge from diverse data sources with varying supervision levels to formulate general object representations, excelling in zero-shot transfer to new data and tasks. Specifically, we employ an image encoder, text encoder, and visual prompter to handle multi-modal inputs, enabling to simultaneously solve various object-centric downstream tasks while maintaining state-of-the-art performance. Demonstrated through extensive training on over five million images from diverse benchmarks, GLEE exhibits remarkable versatility and improved generalization performance, efficiently tackling downstream tasks without the need for task-specific adaptation. By integrating large volumes of automatically labeled data, we further enhance its zero-shot generalization capabilities. Additionally, GLEE is capable of being integrated into Large Language Models, serving as a foundational model to provide universal object-level information for multi-modal tasks. We hope that the versatility and universality of our method will mark a significant step in the development of efficient visual foundation models for AGI systems. The model and code will be released at https://glee-vision.github.io .

Land-use and land cover (LULC) analysis is critical in remote sensing, with wide-ranging applications across diverse fields such as agriculture, utilities, and urban planning. However, automating LULC map generation using machine learning is rendered challenging due to noisy labels. Typically, the ground truths (e.g. ESRI LULC, MapBioMass) have noisy labels that hamper the model's ability to learn to accurately classify the pixels. Further, these erroneous labels can significantly distort the performance metrics of a model, leading to misleading evaluations. Traditionally, the ambiguous labels are rectified using unsupervised algorithms. These algorithms struggle not only with scalability but also with generalization across different geographies. To overcome these challenges, we propose a zero-shot approach using the foundation model, Segment Anything Model (SAM), to automatically delineate different land parcels/regions and leverage them to relabel the unsure pixels by using the local label statistics within each detected region. We achieve a significant reduction in label noise and an improvement in the performance of the downstream segmentation model by approx 5% when trained with denoised labels.

We introduce Moshi, a speech-text foundation model and full-duplex spoken dialogue framework. Current systems for spoken dialogue rely on pipelines of independent components, namely voice activity detection, speech recognition, textual dialogue and text-to-speech. Such frameworks cannot emulate the experience of real conversations. First, their complexity induces a latency of several seconds between interactions. Second, text being the intermediate modality for dialogue, non-linguistic information that modifies meaning -- such as emotion or non-speech sounds -- is lost in the interaction. Finally, they rely on a segmentation into speaker turns, which does not take into account overlapping speech, interruptions and interjections. Moshi solves these independent issues altogether by casting spoken dialogue as speech-to-speech generation. Starting from a text language model backbone, Moshi generates speech as tokens from the residual quantizer of a neural audio codec, while modeling separately its own speech and that of the user into parallel streams. This allows for the removal of explicit speaker turns, and the modeling of arbitrary conversational dynamics. We moreover extend the hierarchical semantic-to-acoustic token generation of previous work to first predict time-aligned text tokens as a prefix to audio tokens. Not only this "Inner Monologue" method significantly improves the linguistic quality of generated speech, but we also illustrate how it can provide streaming speech recognition and text-to-speech. Our resulting model is the first real-time full-duplex spoken large language model, with a theoretical latency of 160ms, 200ms in practice, and is available at https://github.com/kyutai-labs/moshi.

Cardiac magnetic resonance (CMR) is a key investigation in clinical cardiovascular medicine and has been used extensively in population research. However, extracting clinically important measurements such as ejection fraction for diagnosing cardiovascular diseases remains time-consuming and subjective. We developed CineMA, a foundation AI model automating these tasks with limited labels. CineMA is a self-supervised autoencoder model trained on 74,916 cine CMR studies to reconstruct images from masked inputs. After fine-tuning, it was evaluated across eight datasets on 23 tasks from four categories: ventricle and myocardium segmentation, left and right ventricle ejection fraction calculation, disease detection and classification, and landmark localisation. CineMA is the first foundation model for cine CMR to match or outperform convolutional neural networks (CNNs). CineMA demonstrated greater label efficiency than CNNs, achieving comparable or better performance with fewer annotations. This reduces the burden of clinician labelling and supports replacing task-specific training with fine-tuning foundation models in future cardiac imaging applications. Models and code for pre-training and fine-tuning are available at https://github.com/mathpluscode/CineMA, democratising access to high-performance models that otherwise require substantial computational resources, promoting reproducibility and accelerating clinical translation.

Surgery video segmentation is an important topic in the surgical AI field. It allows the AI model to understand the spatial information of a surgical scene. Meanwhile, due to the lack of annotated surgical data, surgery segmentation models suffer from limited performance. With the emergence of SAM2 model, a large foundation model for video segmentation trained on natural videos, zero-shot surgical video segmentation became more realistic but meanwhile remains to be explored. In this paper, we systematically evaluate the performance of SAM2 model in zero-shot surgery video segmentation task. We conducted experiments under different configurations, including different prompting strategies, robustness, etc. Moreover, we conducted an empirical evaluation over the performance, including 9 datasets with 17 different types of surgeries.

Self-supervised image backbones can be used to address complex 2D tasks (e.g., semantic segmentation, object discovery) very efficiently and with little or no downstream supervision. Ideally, 3D backbones for lidar should be able to inherit these properties after distillation of these powerful 2D features. The most recent methods for image-to-lidar distillation on autonomous driving data show promising results, obtained thanks to distillation methods that keep improving. Yet, we still notice a large performance gap when measuring the quality of distilled and fully supervised features by linear probing. In this work, instead of focusing only on the distillation method, we study the effect of three pillars for distillation: the 3D backbone, the pretrained 2D backbones, and the pretraining dataset. In particular, thanks to our scalable distillation method named ScaLR, we show that scaling the 2D and 3D backbones and pretraining on diverse datasets leads to a substantial improvement of the feature quality. This allows us to significantly reduce the gap between the quality of distilled and fully-supervised 3D features, and to improve the robustness of the pretrained backbones to domain gaps and perturbations.

Vision-based robot policy learning, which maps visual inputs to actions, necessitates a holistic understanding of diverse visual tasks beyond single-task needs like classification or segmentation. Inspired by this, we introduce Theia, a vision foundation model for robot learning that distills multiple off-the-shelf vision foundation models trained on varied vision tasks. Theia's rich visual representations encode diverse visual knowledge, enhancing downstream robot learning. Extensive experiments demonstrate that Theia outperforms its teacher models and prior robot learning models using less training data and smaller model sizes. Additionally, we quantify the quality of pre-trained visual representations and hypothesize that higher entropy in feature norm distributions leads to improved robot learning performance. Code and models are available at https://github.com/bdaiinstitute/theia.

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer diagnosis from dermoscopic images, they struggle to meet the complex, multimodal requirements of clinical practice. Here, we introduce PanDerm, a multimodal dermatology foundation model pretrained through self-supervised learning on over 2 million real-world skin disease images from 11 clinical institutions across 4 imaging modalities. We evaluated PanDerm on 28 diverse benchmarks, including skin cancer screening, risk stratification, differential diagnosis of common and rare skin conditions, lesion segmentation, longitudinal monitoring, and metastasis prediction and prognosis. PanDerm achieved state-of-the-art performance across all evaluated tasks, often outperforming existing models when using only 10% of labeled data. We conducted three reader studies to assess PanDerm's potential clinical utility. PanDerm outperformed clinicians by 10.2% in early-stage melanoma detection through longitudinal analysis, improved clinicians' skin cancer diagnostic accuracy by 11% on dermoscopy images, and enhanced non-dermatologist healthcare providers' differential diagnosis by 16.5% across 128 skin conditions on clinical photographs. These results demonstrate PanDerm's potential to improve patient care across diverse clinical scenarios and serve as a model for developing multimodal foundation models in other medical specialties, potentially accelerating the integration of AI support in healthcare. The code can be found at https://github.com/SiyuanYan1/PanDerm.

In contrast to numerous NLP and 2D vision foundational models, learning a 3D foundational model poses considerably greater challenges. This is primarily due to the inherent data variability and diversity of downstream tasks. In this paper, we introduce a novel universal 3D pre-training framework designed to facilitate the acquisition of efficient 3D representation, thereby establishing a pathway to 3D foundational models. Considering that informative 3D features should encode rich geometry and appearance cues that can be utilized to render realistic images, we propose to learn 3D representations by differentiable neural rendering. We train a 3D backbone with a devised volumetric neural renderer by comparing the rendered with the real images. Notably, our approach seamlessly integrates the learned 3D encoder into various downstream tasks. These tasks encompass not only high-level challenges such as 3D detection and segmentation but also low-level objectives like 3D reconstruction and image synthesis, spanning both indoor and outdoor scenarios. Besides, we also illustrate the capability of pre-training a 2D backbone using the proposed methodology, surpassing conventional pre-training methods by a large margin. For the first time, PonderV2 achieves state-of-the-art performance on 11 indoor and outdoor benchmarks, implying its effectiveness. Code and models are available at https://github.com/OpenGVLab/PonderV2.

The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts. However, model training is often difficult due to label scarcity in the medical domain and the model's usage is limited by the specific task and disease for which it is trained. Additionally, most models in histopathology leverage only image data, a stark contrast to how humans teach each other and reason about histopathologic entities. We introduce CONtrastive learning from Captions for Histopathology (CONCH), a visual-language foundation model developed using diverse sources of histopathology images, biomedical text, and notably over 1.17 million image-caption pairs via task-agnostic pretraining. Evaluated on a suite of 13 diverse benchmarks, CONCH can be transferred to a wide range of downstream tasks involving either or both histopathology images and text, achieving state-of-the-art performance on histology image classification, segmentation, captioning, text-to-image and image-to-text retrieval. CONCH represents a substantial leap over concurrent visual-language pretrained systems for histopathology, with the potential to directly facilitate a wide array of machine learning-based workflows requiring minimal or no further supervised fine-tuning.

This paper describes the submission of the UPC Machine Translation group to the IWSLT 2023 Offline Speech Translation task. Our Speech Translation systems utilize foundation models for speech (wav2vec 2.0) and text (mBART50). We incorporate a Siamese pretraining step of the speech and text encoders with CTC and Optimal Transport, to adapt the speech representations to the space of the text model, thus maximizing transfer learning from MT. After this pretraining, we fine-tune our system end-to-end on ST, with Cross Entropy and Knowledge Distillation. Apart from the available ST corpora, we create synthetic data with SegAugment to better adapt our models to the custom segmentations of the IWSLT test sets. Our best single model obtains 31.2 BLEU points on MuST-C tst-COMMON, 29.8 points on IWLST.tst2020 and 33.4 points on the newly released IWSLT.ACLdev2023.

Recent advances in large-scale pretraining have yielded visual foundation models with strong capabilities. Not only can recent models generalize to arbitrary images for their training task, their intermediate representations are useful for other visual tasks such as detection and segmentation. Given that such models can classify, delineate, and localize objects in 2D, we ask whether they also represent their 3D structure? In this work, we analyze the 3D awareness of visual foundation models. We posit that 3D awareness implies that representations (1) encode the 3D structure of the scene and (2) consistently represent the surface across views. We conduct a series of experiments using task-specific probes and zero-shot inference procedures on frozen features. Our experiments reveal several limitations of the current models. Our code and analysis can be found at https://github.com/mbanani/probe3d.

Over 85 million computed tomography (CT) scans are performed annually in the US, of which approximately one quarter focus on the abdomen. Given the current radiologist shortage, there is a large impetus to use artificial intelligence to alleviate the burden of interpreting these complex imaging studies. Prior state-of-the-art approaches for automated medical image interpretation leverage vision language models (VLMs). However, current medical VLMs are generally limited to 2D images and short reports, and do not leverage electronic health record (EHR) data for supervision. We introduce Merlin - a 3D VLM that we train using paired CT scans (6+ million images from 15,331 CTs), EHR diagnosis codes (1.8+ million codes), and radiology reports (6+ million tokens). We evaluate Merlin on 6 task types and 752 individual tasks. The non-adapted (off-the-shelf) tasks include zero-shot findings classification (31 findings), phenotype classification (692 phenotypes), and zero-shot cross-modal retrieval (image to findings and image to impressions), while model adapted tasks include 5-year disease prediction (6 diseases), radiology report generation, and 3D semantic segmentation (20 organs). We perform internal validation on a test set of 5,137 CTs, and external validation on 7,000 clinical CTs and on two public CT datasets (VerSe, TotalSegmentator). Beyond these clinically-relevant evaluations, we assess the efficacy of various network architectures and training strategies to depict that Merlin has favorable performance to existing task-specific baselines. We derive data scaling laws to empirically assess training data needs for requisite downstream task performance. Furthermore, unlike conventional VLMs that require hundreds of GPUs for training, we perform all training on a single GPU.

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical images. In this work, we present our scalable training pipeline for large pathology imaging data, and a comprehensive analysis of various hyperparameter choices and training techniques for building pathology FMs. We release and make publicly available the first batch of our pathology FMs (https://github.com/kaiko-ai/towards_large_pathology_fms) trained on open-access TCGA whole slide images, a commonly used collection of pathology images. The experimental evaluation shows that our models reach state-of-the-art performance on various patch-level downstream tasks, ranging from breast cancer subtyping to colorectal nuclear segmentation. Finally, to unify the evaluation approaches used in the field and to simplify future comparisons of different FMs, we present an open-source framework (https://github.com/kaiko-ai/eva) designed for the consistent evaluation of pathology FMs across various downstream tasks.

Recent works on generalizable NeRFs have shown promising results on novel view synthesis from single or few images. However, such models have rarely been applied on other downstream tasks beyond synthesis such as semantic understanding and parsing. In this paper, we propose a novel framework named FeatureNeRF to learn generalizable NeRFs by distilling pre-trained vision foundation models (e.g., DINO, Latent Diffusion). FeatureNeRF leverages 2D pre-trained foundation models to 3D space via neural rendering, and then extract deep features for 3D query points from NeRF MLPs. Consequently, it allows to map 2D images to continuous 3D semantic feature volumes, which can be used for various downstream tasks. We evaluate FeatureNeRF on tasks of 2D/3D semantic keypoint transfer and 2D/3D object part segmentation. Our extensive experiments demonstrate the effectiveness of FeatureNeRF as a generalizable 3D semantic feature extractor. Our project page is available at https://jianglongye.com/featurenerf/ .

Pre-trained Vision Foundation Models (VFMs) provide strong visual representations for a wide range of applications. In this paper, we continually pre-train prevailing VFMs in a multimodal manner such that they can effortlessly process visual inputs of varying sizes and produce visual representations that are more aligned with language representations, regardless of their original pre-training process. To this end, we introduce CoMP, a carefully designed multimodal pre-training pipeline. CoMP uses a Continual Rotary Position Embedding to support native resolution continual pre-training, and an Alignment Loss between visual and textual features through language prototypes to align multimodal representations. By three-stage training, our VFMs achieve remarkable improvements not only in multimodal understanding but also in other downstream tasks such as classification and segmentation. Remarkably, CoMP-SigLIP achieves scores of 66.7 on ChartQA and 75.9 on DocVQA with a 0.5B LLM, while maintaining an 87.4% accuracy on ImageNet-1K and a 49.5 mIoU on ADE20K under frozen chunk evaluation.

Pre-trained on a large and diverse dataset, the segment anything model (SAM) is the first promptable foundation model in computer vision aiming at object segmentation tasks. In this work, we evaluate SAM for the task of nuclear instance segmentation performance with zero-shot learning and finetuning. We compare SAM with other representative methods in nuclear instance segmentation, especially in the context of model generalisability. To achieve automatic nuclear instance segmentation, we propose using a nuclei detection model to provide bounding boxes or central points of nu-clei as visual prompts for SAM in generating nuclear instance masks from histology images.

Segment Anything Model (SAM) is a foundation model for interactive segmentation, and it has catalyzed major advances in generative AI, computational photography, and medical imaging. This model takes in an arbitrary user input and provides segmentation masks of the corresponding objects. It is our goal to develop a version of SAM that is appropriate for use in a photography app. The original SAM model has a few challenges in this setting. First, original SAM a 600 million parameter based on ViT-H, and its high computational cost and large model size that are not suitable for todays mobile hardware. We address this by proposing the SqueezeSAM model architecture, which is 50x faster and 100x smaller than SAM. Next, when a user takes a photo on their phone, it might not occur to them to click on the image and get a mask. Our solution is to use salient object detection to generate the first few clicks. This produces an initial segmentation mask that the user can interactively edit. Finally, when a user clicks on an object, they typically expect all related pieces of the object to be segmented. For instance, if a user clicks on a person t-shirt in a photo, they expect the whole person to be segmented, but SAM typically segments just the t-shirt. We address this with a new data augmentation scheme, and the end result is that if the user clicks on a person holding a basketball, the person and the basketball are all segmented together.

The Segment Anything Model 2 (SAM 2) has emerged as a powerful foundation model for object segmentation in both images and videos, paving the way for various downstream video applications. The crucial design of SAM 2 for video segmentation is its memory module, which prompts object-aware memories from previous frames for current frame prediction. However, its greedy-selection memory design suffers from the "error accumulation" problem, where an errored or missed mask will cascade and influence the segmentation of the subsequent frames, which limits the performance of SAM 2 toward complex long-term videos. To this end, we introduce SAM2Long, an improved training-free video object segmentation strategy, which considers the segmentation uncertainty within each frame and chooses the video-level optimal results from multiple segmentation pathways in a constrained tree search manner. In practice, we maintain a fixed number of segmentation pathways throughout the video. For each frame, multiple masks are proposed based on the existing pathways, creating various candidate branches. We then select the same fixed number of branches with higher cumulative scores as the new pathways for the next frame. After processing the final frame, the pathway with the highest cumulative score is chosen as the final segmentation result. Benefiting from its heuristic search design, SAM2Long is robust toward occlusions and object reappearances, and can effectively segment and track objects for complex long-term videos. Notably, SAM2Long achieves an average improvement of 3.0 points across all 24 head-to-head comparisons, with gains of up to 5.3 points in J&F on long-term video object segmentation benchmarks such as SA-V and LVOS. The code is released at https://github.com/Mark12Ding/SAM2Long.

In medical imaging, the primary challenge is collecting large-scale labeled data due to privacy concerns, logistics, and high labeling costs. In this work, we present the UK Biobank Organs and Bones (UKBOB), the largest labeled dataset of body organs, comprising 51,761 MRI 3D samples (equivalent to 17.9 million 2D images) and more than 1.37 billion 2D segmentation masks of 72 organs, all based on the UK Biobank MRI dataset. We utilize automatic labeling, introduce an automated label cleaning pipeline with organ-specific filters, and manually annotate a subset of 300 MRIs with 11 abdominal classes to validate the quality (referred to as UKBOB-manual). This approach allows for scaling up the dataset collection while maintaining confidence in the labels. We further confirm the validity of the labels by demonstrating zero-shot generalization of trained models on the filtered UKBOB to other small labeled datasets from similar domains (e.g., abdominal MRI). To further mitigate the effect of noisy labels, we propose a novel method called Entropy Test-time Adaptation (ETTA) to refine the segmentation output. We use UKBOB to train a foundation model, Swin-BOB, for 3D medical image segmentation based on the Swin-UNetr architecture, achieving state-of-the-art results in several benchmarks in 3D medical imaging, including the BRATS brain MRI tumor challenge (with a 0.4% improvement) and the BTCV abdominal CT scan benchmark (with a 1.3% improvement). The pre-trained models and the code are available at https://emmanuelleb985.github.io/ukbob , and the filtered labels will be made available with the UK Biobank.

Two challenges are presented when parsing road scenes in UAV images. First, the high resolution of UAV images makes processing difficult. Second, supervised deep learning methods require a large amount of manual annotations to train robust and accurate models. In this paper, an unsupervised road parsing framework that leverages recent advances in vision language models and fundamental computer vision model is introduced.Initially, a vision language model is employed to efficiently process ultra-large resolution UAV images to quickly detect road regions of interest in the images. Subsequently, the vision foundation model SAM is utilized to generate masks for the road regions without category information. Following that, a self-supervised representation learning network extracts feature representations from all masked regions. Finally, an unsupervised clustering algorithm is applied to cluster these feature representations and assign IDs to each cluster. The masked regions are combined with the corresponding IDs to generate initial pseudo-labels, which initiate an iterative self-training process for regular semantic segmentation. The proposed method achieves an impressive 89.96% mIoU on the development dataset without relying on any manual annotation. Particularly noteworthy is the extraordinary flexibility of the proposed method, which even goes beyond the limitations of human-defined categories and is able to acquire knowledge of new categories from the dataset itself.

Click-based interactive image segmentation aims at extracting objects with a limited user clicking. A hierarchical backbone is the de-facto architecture for current methods. Recently, the plain, non-hierarchical Vision Transformer (ViT) has emerged as a competitive backbone for dense prediction tasks. This design allows the original ViT to be a foundation model that can be finetuned for downstream tasks without redesigning a hierarchical backbone for pretraining. Although this design is simple and has been proven effective, it has not yet been explored for interactive image segmentation. To fill this gap, we propose SimpleClick, the first interactive segmentation method that leverages a plain backbone. Based on the plain backbone, we introduce a symmetric patch embedding layer that encodes clicks into the backbone with minor modifications to the backbone itself. With the plain backbone pretrained as a masked autoencoder (MAE), SimpleClick achieves state-of-the-art performance. Remarkably, our method achieves 4.15 NoC@90 on SBD, improving 21.8% over the previous best result. Extensive evaluation on medical images demonstrates the generalizability of our method. We further develop an extremely tiny ViT backbone for SimpleClick and provide a detailed computational analysis, highlighting its suitability as a practical annotation tool.

Anomaly detection is a practical and challenging task due to the scarcity of anomaly samples in industrial inspection. Some existing anomaly detection methods address this issue by synthesizing anomalies with noise or external data. However, there is always a large semantic gap between synthetic and real-world anomalies, resulting in weak performance in anomaly detection. To solve the problem, we propose a few-shot Anomaly-driven Generation (AnoGen) method, which guides the diffusion model to generate realistic and diverse anomalies with only a few real anomalies, thereby benefiting training anomaly detection models. Specifically, our work is divided into three stages. In the first stage, we learn the anomaly distribution based on a few given real anomalies and inject the learned knowledge into an embedding. In the second stage, we use the embedding and given bounding boxes to guide the diffusion model to generate realistic and diverse anomalies on specific objects (or textures). In the final stage, we propose a weakly-supervised anomaly detection method to train a more powerful model with generated anomalies. Our method builds upon DRAEM and DesTSeg as the foundation model and conducts experiments on the commonly used industrial anomaly detection dataset, MVTec. The experiments demonstrate that our generated anomalies effectively improve the model performance of both anomaly classification and segmentation tasks simultaneously, \eg, DRAEM and DseTSeg achieved a 5.8\% and 1.5\% improvement in AU-PR metric on segmentation task, respectively. The code and generated anomalous data are available at https://github.com/gaobb/AnoGen.

Rapid advancements in medical image segmentation performance have been significantly driven by the development of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs). These models follow the discriminative pixel-wise classification learning paradigm and often have limited ability to generalize across diverse medical imaging datasets. In this manuscript, we introduce Generative Medical Segmentation (GMS), a novel approach leveraging a generative model to perform image segmentation. Concretely, GMS employs a robust pre-trained vision foundation model to extract latent representations for images and corresponding ground truth masks, followed by a model that learns a mapping function from the image to the mask in the latent space. Once trained, the model generates an estimated segmentation mask using the pre-trained vision foundation model to decode the predicted latent representation back into the image space. The design of GMS leads to fewer trainable parameters in the model which reduces the risk of overfitting and enhances its generalization capability. Our experimental analysis across five public datasets in different medical imaging domains demonstrates GMS outperforms existing discriminative and generative segmentation models. Furthermore, GMS is able to generalize well across datasets from different centers within the same imaging modality. Our experiments suggest GMS offers a scalable and effective solution for medical image segmentation. GMS implementation and trained model weights are available at https://github.com/King-HAW/GMS.

Video instance segmentation requires classifying, segmenting, and tracking every object across video frames. Unlike existing approaches that rely on masks, boxes, or category labels, we propose UVIS, a novel Unsupervised Video Instance Segmentation (UVIS) framework that can perform video instance segmentation without any video annotations or dense label-based pretraining. Our key insight comes from leveraging the dense shape prior from the self-supervised vision foundation model DINO and the openset recognition ability from the image-caption supervised vision-language model CLIP. Our UVIS framework consists of three essential steps: frame-level pseudo-label generation, transformer-based VIS model training, and query-based tracking. To improve the quality of VIS predictions in the unsupervised setup, we introduce a dual-memory design. This design includes a semantic memory bank for generating accurate pseudo-labels and a tracking memory bank for maintaining temporal consistency in object tracks. We evaluate our approach on three standard VIS benchmarks, namely YoutubeVIS-2019, YoutubeVIS-2021, and Occluded VIS. Our UVIS achieves 21.1 AP on YoutubeVIS-2019 without any video annotations or dense pretraining, demonstrating the potential of our unsupervised VIS framework.

The interactive segmentation task consists in the creation of object segmentation masks based on user interactions. The most common way to guide a model towards producing a correct segmentation consists in clicks on the object and background. The recently published Segment Anything Model (SAM) supports a generalized version of the interactive segmentation problem and has been trained on an object segmentation dataset which contains 1.1B masks. Though being trained extensively and with the explicit purpose of serving as a foundation model, we show significant limitations of SAM when being applied for interactive segmentation on novel domains or object types. On the used datasets, SAM displays a failure rate FR_{30}@90 of up to 72.6 %. Since we still want such foundation models to be immediately applicable, we present a framework that can adapt SAM during immediate usage. For this we will leverage the user interactions and masks, which are constructed during the interactive segmentation process. We use this information to generate pseudo-labels, which we use to compute a loss function and optimize a part of the SAM model. The presented method causes a relative reduction of up to 48.1 % in the FR_{20}@85 and 46.6 % in the FR_{30}@90 metrics.

In-context segmentation aims at segmenting novel images using a few labeled example images, termed as "in-context examples", exploring content similarities between examples and the target. The resulting models can be generalized seamlessly to novel segmentation tasks, significantly reducing the labeling and training costs compared with conventional pipelines. However, in-context segmentation is more challenging than classic ones due to its meta-learning nature, requiring the model to learn segmentation rules conditioned on a few samples, not just the segmentation. Unlike previous work with ad-hoc or non-end-to-end designs, we propose SEGIC, an end-to-end segment-in-context framework built upon a single vision foundation model (VFM). In particular, SEGIC leverages the emergent correspondence within VFM to capture dense relationships between target images and in-context samples. As such, information from in-context samples is then extracted into three types of instructions, i.e. geometric, visual, and meta instructions, serving as explicit conditions for the final mask prediction. SEGIC is a straightforward yet effective approach that yields state-of-the-art performance on one-shot segmentation benchmarks. Notably, SEGIC can be easily generalized to diverse tasks, including video object segmentation and open-vocabulary segmentation. Code will be available at https://github.com/MengLcool/SEGIC.

Medical image segmentation involves partitioning medical images into meaningful regions, with a focus on identifying anatomical structures and lesions. It has broad applications in healthcare, and deep learning methods have enabled significant advancements in automating this process. Recently, the introduction of the Segmentation Anything Model (SAM), the first foundation model for segmentation task, has prompted researchers to adapt it for the medical domain to improve performance across various tasks. However, SAM's large model size and high GPU requirements hinder its scalability and development in the medical domain. In this work, we propose MCP-MedSAM, a powerful and lightweight medical SAM model designed to be trainable on a single A100 GPU with 40GB of memory within one day while delivering superior segmentation performance. Recognizing the significant internal differences between modalities and the need for direct segmentation target information within bounding boxes, we introduce two kinds of prompts: the modality prompt and the content prompt. After passing through the prompt encoder, their embedding representations can further improve the segmentation performance by incorporating more relevant information without adding significant training overhead. Additionally, we adopt an effective modality-based data sampling strategy to address data imbalance between modalities, ensuring more balanced performance across all modalities. Our method was trained and evaluated using a large-scale challenge dataset, compared to top-ranking methods on the challenge leaderboard, MCP-MedSAM achieved superior performance while requiring only one day of training on a single GPU. The code is publicly available at blue{https://github.com/dong845/MCP-MedSAM}.}

Recent "segment anything" efforts show promise by learning from large-scale data, but adapting such models directly to medical images remains challenging due to the complexity of medical data, noisy annotations, and continual learning requirements across diverse modalities and anatomical structures. In this work, we propose SAMed-2, a new foundation model for medical image segmentation built upon the SAM-2 architecture. Specifically, we introduce a temporal adapter into the image encoder to capture image correlations and a confidence-driven memory mechanism to store high-certainty features for later retrieval. This memory-based strategy counters the pervasive noise in large-scale medical datasets and mitigates catastrophic forgetting when encountering new tasks or modalities. To train and evaluate SAMed-2, we curate MedBank-100k, a comprehensive dataset spanning seven imaging modalities and 21 medical segmentation tasks. Our experiments on both internal benchmarks and 10 external datasets demonstrate superior performance over state-of-the-art baselines in multi-task scenarios. The code is available at: https://github.com/ZhilingYan/Medical-SAM-Bench.

On top of Segment Anything Model (SAM), SAM 2 further extends its capability from image to video inputs through a memory bank mechanism and obtains a remarkable performance compared with previous methods, making it a foundation model for video segmentation task. In this paper, we aim at making SAM 2 much more efficient so that it even runs on mobile devices while maintaining a comparable performance. Despite several works optimizing SAM for better efficiency, we find they are not sufficient for SAM 2 because they all focus on compressing the image encoder, while our benchmark shows that the newly introduced memory attention blocks are also the latency bottleneck. Given this observation, we propose EdgeTAM, which leverages a novel 2D Spatial Perceiver to reduce the computational cost. In particular, the proposed 2D Spatial Perceiver encodes the densely stored frame-level memories with a lightweight Transformer that contains a fixed set of learnable queries. Given that video segmentation is a dense prediction task, we find preserving the spatial structure of the memories is essential so that the queries are split into global-level and patch-level groups. We also propose a distillation pipeline that further improves the performance without inference overhead. As a result, EdgeTAM achieves 87.7, 70.0, 72.3, and 71.7 J&F on DAVIS 2017, MOSE, SA-V val, and SA-V test, while running at 16 FPS on iPhone 15 Pro Max.

The Segment Anything Model (SAM) has demonstrated outstanding adaptation to medical image segmentation but still faces three major challenges. Firstly, the huge computational costs of SAM limit its real-world applicability. Secondly, SAM depends on manual annotations (e.g., points, boxes) as prompts, which are laborious and impractical in clinical scenarios. Thirdly, SAM handles all segmentation targets equally, which is suboptimal for diverse medical modalities with inherent heterogeneity. To address these issues, we propose an Efficient Self-Prompting SAM for universal medical image segmentation, named ESP-MedSAM. We devise a Multi-Modal Decoupled Knowledge Distillation (MMDKD) strategy to distil common image knowledge and domain-specific medical knowledge from the foundation model to train a lightweight image encoder and a modality controller. Further, they combine with the additionally introduced Self-Patch Prompt Generator (SPPG) and Query-Decoupled Modality Decoder (QDMD) to construct ESP-MedSAM. Specifically, SPPG aims to generate a set of patch prompts automatically and QDMD leverages a one-to-one strategy to provide an independent decoding channel for every modality. Extensive experiments indicate that ESP-MedSAM outperforms state-of-the-arts in diverse medical imaging segmentation takes, displaying superior zero-shot learning and modality transfer ability. Especially, our framework uses only 31.4% parameters compared to SAM-Base.

We introduce VideoLISA, a video-based multimodal large language model designed to tackle the problem of language-instructed reasoning segmentation in videos. Leveraging the reasoning capabilities and world knowledge of large language models, and augmented by the Segment Anything Model, VideoLISA generates temporally consistent segmentation masks in videos based on language instructions. Existing image-based methods, such as LISA, struggle with video tasks due to the additional temporal dimension, which requires temporal dynamic understanding and consistent segmentation across frames. VideoLISA addresses these challenges by integrating a Sparse Dense Sampling strategy into the video-LLM, which balances temporal context and spatial detail within computational constraints. Additionally, we propose a One-Token-Seg-All approach using a specially designed <TRK> token, enabling the model to segment and track objects across multiple frames. Extensive evaluations on diverse benchmarks, including our newly introduced ReasonVOS benchmark, demonstrate VideoLISA's superior performance in video object segmentation tasks involving complex reasoning, temporal understanding, and object tracking. While optimized for videos, VideoLISA also shows promising generalization to image segmentation, revealing its potential as a unified foundation model for language-instructed object segmentation. Code and model will be available at: https://github.com/showlab/VideoLISA.

Contrastive Language-Image Pre-training (CLIP) exhibits strong zero-shot classification ability on various image-level tasks, leading to the research to adapt CLIP for pixel-level open-vocabulary semantic segmentation without additional training. The key is to improve spatial representation of image-level CLIP, such as replacing self-attention map at last layer with self-self attention map or vision foundation model based attention map. In this paper, we present a novel hierarchical framework, named CLIPer, that hierarchically improves spatial representation of CLIP. The proposed CLIPer includes an early-layer fusion module and a fine-grained compensation module. We observe that, the embeddings and attention maps at early layers can preserve spatial structural information. Inspired by this, we design the early-layer fusion module to generate segmentation map with better spatial coherence. Afterwards, we employ a fine-grained compensation module to compensate the local details using the self-attention maps of diffusion model. We conduct the experiments on seven segmentation datasets. Our proposed CLIPer achieves the state-of-the-art performance on these datasets. For instance, using ViT-L, CLIPer has the mIoU of 69.8% and 43.3% on VOC and COCO Object, outperforming ProxyCLIP by 9.2% and 4.1% respectively.

We present SAM4D, a multi-modal and temporal foundation model designed for promptable segmentation across camera and LiDAR streams. Unified Multi-modal Positional Encoding (UMPE) is introduced to align camera and LiDAR features in a shared 3D space, enabling seamless cross-modal prompting and interaction. Additionally, we propose Motion-aware Cross-modal Memory Attention (MCMA), which leverages ego-motion compensation to enhance temporal consistency and long-horizon feature retrieval, ensuring robust segmentation across dynamically changing autonomous driving scenes. To avoid annotation bottlenecks, we develop a multi-modal automated data engine that synergizes VFM-driven video masklets, spatiotemporal 4D reconstruction, and cross-modal masklet fusion. This framework generates camera-LiDAR aligned pseudo-labels at a speed orders of magnitude faster than human annotation while preserving VFM-derived semantic fidelity in point cloud representations. We conduct extensive experiments on the constructed Waymo-4DSeg, which demonstrate the powerful cross-modal segmentation ability and great potential in data annotation of proposed SAM4D.

Purpose: Foundation models, trained on multitudes of public datasets, often require additional fine-tuning or re-prompting mechanisms to be applied to visually distinct target domains such as surgical videos. Further, without domain knowledge, they cannot model the specific semantics of the target domain. Hence, when applied to surgical video segmentation, they fail to generalise to sections where previously tracked objects leave the scene or new objects enter. Methods: We propose SASVi, a novel re-prompting mechanism based on a frame-wise Mask R-CNN Overseer model, which is trained on a minimal amount of scarcely available annotations for the target domain. This model automatically re-prompts the foundation model SAM2 when the scene constellation changes, allowing for temporally smooth and complete segmentation of full surgical videos. Results: Re-prompting based on our Overseer model significantly improves the temporal consistency of surgical video segmentation compared to similar prompting techniques and especially frame-wise segmentation, which neglects temporal information, by at least 1.5%. Our proposed approach allows us to successfully deploy SAM2 to surgical videos, which we quantitatively and qualitatively demonstrate for three different cholecystectomy and cataract surgery datasets. Conclusion: SASVi can serve as a new baseline for smooth and temporally consistent segmentation of surgical videos with scarcely available annotation data. Our method allows us to leverage scarce annotations and obtain complete annotations for full videos of the large-scale counterpart datasets. We make those annotations publicly available, providing extensive annotation data for the future development of surgical data science models.

We present Segment Anything Model 2 (SAM 2), a foundation model towards solving promptable visual segmentation in images and videos. We build a data engine, which improves model and data via user interaction, to collect the largest video segmentation dataset to date. Our model is a simple transformer architecture with streaming memory for real-time video processing. SAM 2 trained on our data provides strong performance across a wide range of tasks. In video segmentation, we observe better accuracy, using 3x fewer interactions than prior approaches. In image segmentation, our model is more accurate and 6x faster than the Segment Anything Model (SAM). We believe that our data, model, and insights will serve as a significant milestone for video segmentation and related perception tasks. We are releasing a version of our model, the dataset and an interactive demo.

We introduce FruitNeRF, a unified novel fruit counting framework that leverages state-of-the-art view synthesis methods to count any fruit type directly in 3D. Our framework takes an unordered set of posed images captured by a monocular camera and segments fruit in each image. To make our system independent of the fruit type, we employ a foundation model that generates binary segmentation masks for any fruit. Utilizing both modalities, RGB and semantic, we train a semantic neural radiance field. Through uniform volume sampling of the implicit Fruit Field, we obtain fruit-only point clouds. By applying cascaded clustering on the extracted point cloud, our approach achieves precise fruit count.The use of neural radiance fields provides significant advantages over conventional methods such as object tracking or optical flow, as the counting itself is lifted into 3D. Our method prevents double counting fruit and avoids counting irrelevant fruit.We evaluate our methodology using both real-world and synthetic datasets. The real-world dataset consists of three apple trees with manually counted ground truths, a benchmark apple dataset with one row and ground truth fruit location, while the synthetic dataset comprises various fruit types including apple, plum, lemon, pear, peach, and mango.Additionally, we assess the performance of fruit counting using the foundation model compared to a U-Net.

Image pyramids are widely adopted in top-performing methods to obtain multi-scale features for precise visual perception and understanding. However, current image pyramids use the same large-scale model to process multiple resolutions of images, leading to significant computational cost. To address this challenge, we propose a novel network architecture, called Parameter-Inverted Image Pyramid Networks (PIIP). Specifically, PIIP uses pretrained models (ViTs or CNNs) as branches to process multi-scale images, where images of higher resolutions are processed by smaller network branches to balance computational cost and performance. To integrate information from different spatial scales, we further propose a novel cross-branch feature interaction mechanism. To validate PIIP, we apply it to various perception models and a representative multimodal large language model called LLaVA, and conduct extensive experiments on various tasks such as object detection, segmentation, image classification and multimodal understanding. PIIP achieves superior performance compared to single-branch and existing multi-resolution approaches with lower computational cost. When applied to InternViT-6B, a large-scale vision foundation model, PIIP can improve its performance by 1%-2% on detection and segmentation with only 40%-60% of the original computation, finally achieving 60.0 box AP on MS COCO and 59.7 mIoU on ADE20K. For multimodal understanding, our PIIP-LLaVA achieves 73.0% accuracy on TextVQA and 74.5% on MMBench with only 2.8M training data. Our code is released at https://github.com/OpenGVLab/PIIP.

Image pyramids are commonly used in modern computer vision tasks to obtain multi-scale features for precise understanding of images. However, image pyramids process multiple resolutions of images using the same large-scale model, which requires significant computational cost. To overcome this issue, we propose a novel network architecture known as the Parameter-Inverted Image Pyramid Networks (PIIP). Our core idea is to use models with different parameter sizes to process different resolution levels of the image pyramid, thereby balancing computational efficiency and performance. Specifically, the input to PIIP is a set of multi-scale images, where higher resolution images are processed by smaller networks. We further propose a feature interaction mechanism to allow features of different resolutions to complement each other and effectively integrate information from different spatial scales. Extensive experiments demonstrate that the PIIP achieves superior performance in tasks such as object detection, segmentation, and image classification, compared to traditional image pyramid methods and single-branch networks, while reducing computational cost. Notably, when applying our method on a large-scale vision foundation model InternViT-6B, we improve its performance by 1%-2% on detection and segmentation with only 40%-60% of the original computation. These results validate the effectiveness of the PIIP approach and provide a new technical direction for future vision computing tasks. Our code and models are available at https://github.com/OpenGVLab/PIIP.

Following the gaze of other people and analyzing the target they are looking at can help us understand what they are thinking, and doing, and predict the actions that may follow. Existing methods for gaze following struggle to perform well in natural scenes with diverse objects, and focus on gaze points rather than objects, making it difficult to deliver clear semantics and accurate scope of the targets. To address this shortcoming, we propose a novel gaze target prediction solution named GazeSeg, that can fully utilize the spatial visual field of the person as guiding information and lead to a progressively coarse-to-fine gaze target segmentation and recognition process. Specifically, a prompt-based visual foundation model serves as the encoder, working in conjunction with three distinct decoding modules (e.g. FoV perception, heatmap generation, and segmentation) to form the framework for gaze target prediction. Then, with the head bounding box performed as an initial prompt, GazeSeg obtains the FoV map, heatmap, and segmentation map progressively, leading to a unified framework for multiple tasks (e.g. direction estimation, gaze target segmentation, and recognition). In particular, to facilitate this research, we construct and release a new dataset, comprising 72k images with pixel-level annotations and 270 categories of gaze targets, built upon the GazeFollow dataset. The quantitative evaluation shows that our approach achieves the Dice of 0.325 in gaze target segmentation and 71.7% top-5 recognition. Meanwhile, our approach also outperforms previous state-of-the-art methods, achieving 0.953 in AUC on the gaze-following task. The dataset and code will be released.

This work presents Sa2VA, the first unified model for dense grounded understanding of both images and videos. Unlike existing multi-modal large language models, which are often limited to specific modalities and tasks, Sa2VA supports a wide range of image and video tasks, including referring segmentation and conversation, with minimal one-shot instruction tuning. Sa2VA combines SAM-2, a foundation video segmentation model, with LLaVA, an advanced vision-language model, and unifies text, image, and video into a shared LLM token space. Using the LLM, Sa2VA generates instruction tokens that guide SAM-2 in producing precise masks, enabling a grounded, multi-modal understanding of both static and dynamic visual content. Additionally, we introduce Ref-SAV, an auto-labeled dataset containing over 72k object expressions in complex video scenes, designed to boost model performance. We also manually validate 2k video objects in the Ref-SAV datasets to benchmark referring video object segmentation in complex environments. Experiments show that Sa2VA achieves state-of-the-art across multiple tasks, particularly in referring video object segmentation, highlighting its potential for complex real-world applications.

Generalized few-shot 3D point cloud segmentation (GFS-PCS) adapts models to new classes with few support samples while retaining base class segmentation. Existing GFS-PCS methods enhance prototypes via interacting with support or query features but remain limited by sparse knowledge from few-shot samples. Meanwhile, 3D vision-language models (3D VLMs), generalizing across open-world novel classes, contain rich but noisy novel class knowledge. In this work, we introduce a GFS-PCS framework that synergizes dense but noisy pseudo-labels from 3D VLMs with precise yet sparse few-shot samples to maximize the strengths of both, named GFS-VL. Specifically, we present a prototype-guided pseudo-label selection to filter low-quality regions, followed by an adaptive infilling strategy that combines knowledge from pseudo-label contexts and few-shot samples to adaptively label the filtered, unlabeled areas. Additionally, we design a novel-base mix strategy to embed few-shot samples into training scenes, preserving essential context for improved novel class learning. Moreover, recognizing the limited diversity in current GFS-PCS benchmarks, we introduce two challenging benchmarks with diverse novel classes for comprehensive generalization evaluation. Experiments validate the effectiveness of our framework across models and datasets. Our approach and benchmarks provide a solid foundation for advancing GFS-PCS in the real world. The code is at https://github.com/ZhaochongAn/GFS-VL

The Diffusion Model has not only garnered noteworthy achievements in the realm of image generation but has also demonstrated its potential as an effective pretraining method utilizing unlabeled data. Drawing from the extensive potential unveiled by the Diffusion Model in both semantic correspondence and open vocabulary segmentation, our work initiates an investigation into employing the Latent Diffusion Model for Few-shot Semantic Segmentation. Recently, inspired by the in-context learning ability of large language models, Few-shot Semantic Segmentation has evolved into In-context Segmentation tasks, morphing into a crucial element in assessing generalist segmentation models. In this context, we concentrate on Few-shot Semantic Segmentation, establishing a solid foundation for the future development of a Diffusion-based generalist model for segmentation. Our initial focus lies in understanding how to facilitate interaction between the query image and the support image, resulting in the proposal of a KV fusion method within the self-attention framework. Subsequently, we delve deeper into optimizing the infusion of information from the support mask and simultaneously re-evaluating how to provide reasonable supervision from the query mask. Based on our analysis, we establish a simple and effective framework named DiffewS, maximally retaining the original Latent Diffusion Model's generative framework and effectively utilizing the pre-training prior. Experimental results demonstrate that our method significantly outperforms the previous SOTA models in multiple settings.

Referring video object segmentation aims to segment the object in a video corresponding to a given natural language expression. While prior works have explored various referring scenarios, including motion-centric or multi-instance expressions, most approaches still focus on localizing a single target object in isolation. However, in comprehensive video understanding, an object's role is often defined by its interactions with other entities, which are largely overlooked in existing datasets and models. In this work, we introduce Interaction-aware referring video object sgementation (InterRVOS), a new task that requires segmenting both actor and target entities involved in an interaction. Each interactoin is described through a pair of complementary expressions from different semantic perspectives, enabling fine-grained modeling of inter-object relationships. To tackle this task, we propose InterRVOS-8K, the large-scale and automatically constructed dataset containing diverse interaction-aware expressions with corresponding masks, including challenging cases such as motion-only multi-instance expressions. We also present a baseline architecture, ReVIOSa, designed to handle actor-target segmentation from a single expression, achieving strong performance in both standard and interaction-focused settings. Furthermore, we introduce an actor-target-aware evalaution setting that enables a more targeted assessment of interaction understanding. Experimental results demonstrate that our approach outperforms prior methods in modeling complex object interactions for referring video object segmentation task, establishing a strong foundation for future research in interaction-centric video understanding. Our project page is available at https://cvlab-kaist.github.io/InterRVOS.

While MLLMs have demonstrated adequate image understanding capabilities, they still struggle with pixel-level comprehension, limiting their practical applications. Current evaluation tasks like VQA and visual grounding remain too coarse to assess fine-grained pixel comprehension accurately. Though segmentation is foundational for pixel-level understanding, existing methods often require MLLMs to generate implicit tokens, decoded through external pixel decoders. This approach disrupts the MLLM's text output space, potentially compromising language capabilities and reducing flexibility and extensibility, while failing to reflect the model's intrinsic pixel-level understanding. Thus, we introduce the Human-Like Mask Annotation Task (HLMAT), a new paradigm where MLLMs mimic human annotators using interactive segmentation tools. Modeling segmentation as a multi-step Markov Decision Process, HLMAT enables MLLMs to iteratively generate text-based click points, achieving high-quality masks without architectural changes or implicit tokens. Through this setup, we develop SegAgent, a model fine-tuned on human-like annotation trajectories, which achieves performance comparable to state-of-the-art (SOTA) methods and supports additional tasks like mask refinement and annotation filtering. HLMAT provides a protocol for assessing fine-grained pixel understanding in MLLMs and introduces a vision-centric, multi-step decision-making task that facilitates exploration of MLLMs' visual reasoning abilities. Our adaptations of policy improvement method StaR and PRM-guided tree search further enhance model robustness in complex segmentation tasks, laying a foundation for future advancements in fine-grained visual perception and multi-step decision-making for MLLMs.

In the evolving landscape of computer vision, foundation models have emerged as pivotal tools, exhibiting exceptional adaptability to a myriad of tasks. Among these, the Segment Anything Model (SAM) by Meta AI has distinguished itself in image segmentation. However, SAM, like its counterparts, encounters limitations in specific niche applications, prompting a quest for enhancement strategies that do not compromise its inherent capabilities. This paper introduces ASAM, a novel methodology that amplifies SAM's performance through adversarial tuning. We harness the potential of natural adversarial examples, inspired by their successful implementation in natural language processing. By utilizing a stable diffusion model, we augment a subset (1%) of the SA-1B dataset, generating adversarial instances that are more representative of natural variations rather than conventional imperceptible perturbations. Our approach maintains the photorealism of adversarial examples and ensures alignment with original mask annotations, thereby preserving the integrity of the segmentation task. The fine-tuned ASAM demonstrates significant improvements across a diverse range of segmentation tasks without necessitating additional data or architectural modifications. The results of our extensive evaluations confirm that ASAM establishes new benchmarks in segmentation tasks, thereby contributing to the advancement of foundational models in computer vision. Our project page is in https://asam2024.github.io/.

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently using only a few training samples, e.g., in-context learning. Yet, the application of such learning paradigms in medical image analysis remains scarce due to the shortage of publicly accessible data and benchmarks. In this paper, we aim at approaches adapting the foundation models for medical image classification and present a novel dataset and benchmark for the evaluation, i.e., examining the overall performance of accommodating the large-scale foundation models downstream on a set of diverse real-world clinical tasks. We collect five sets of medical imaging data from multiple institutes targeting a variety of real-world clinical tasks (22,349 images in total), i.e., thoracic diseases screening in X-rays, pathological lesion tissue screening, lesion detection in endoscopy images, neonatal jaundice evaluation, and diabetic retinopathy grading. Results of multiple baseline methods are demonstrated using the proposed dataset from both accuracy and cost-effective perspectives.

The advent of foundation models has revolutionized the fields of natural language processing and computer vision, paving the way for their application in autonomous driving (AD). This survey presents a comprehensive review of more than 40 research papers, demonstrating the role of foundation models in enhancing AD. Large language models contribute to planning and simulation in AD, particularly through their proficiency in reasoning, code generation and translation. In parallel, vision foundation models are increasingly adapted for critical tasks such as 3D object detection and tracking, as well as creating realistic driving scenarios for simulation and testing. Multi-modal foundation models, integrating diverse inputs, exhibit exceptional visual understanding and spatial reasoning, crucial for end-to-end AD. This survey not only provides a structured taxonomy, categorizing foundation models based on their modalities and functionalities within the AD domain but also delves into the methods employed in current research. It identifies the gaps between existing foundation models and cutting-edge AD approaches, thereby charting future research directions and proposing a roadmap for bridging these gaps.

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly heterogeneous tiles extracted from whole-slide images (WSIs) of real-world patient samples. The performance of these FMs is significantly influenced by the size, diversity, and balance of the pre-training data. However, data selection has been primarily guided by expert knowledge at the WSI level, focusing on factors such as disease classification and tissue types, while largely overlooking the granular details available at the tile level. In this paper, we investigate the potential of unsupervised automatic data curation at the tile-level, taking into account 350 million tiles. Specifically, we apply hierarchical clustering trees to pre-extracted tile embeddings, allowing us to sample balanced datasets uniformly across the embedding space of the pretrained FM. We further identify these datasets are subject to a trade-off between size and balance, potentially compromising the quality of representations learned by FMs, and propose tailored batch sampling strategies to mitigate this effect. We demonstrate the effectiveness of our method through improved performance on a diverse range of clinically relevant downstream tasks.

We introduce the Segment Anything (SA) project: a new task, model, and dataset for image segmentation. Using our efficient model in a data collection loop, we built the largest segmentation dataset to date (by far), with over 1 billion masks on 11M licensed and privacy respecting images. The model is designed and trained to be promptable, so it can transfer zero-shot to new image distributions and tasks. We evaluate its capabilities on numerous tasks and find that its zero-shot performance is impressive -- often competitive with or even superior to prior fully supervised results. We are releasing the Segment Anything Model (SAM) and corresponding dataset (SA-1B) of 1B masks and 11M images at https://segment-anything.com to foster research into foundation models for computer vision.

Foundation vision or vision-language models are trained on large unlabeled or noisy data and learn robust representations that can achieve impressive zero- or few-shot performance on diverse tasks. Given these properties, they are a natural fit for active learning (AL), which aims to maximize labeling efficiency. However, the full potential of foundation models has not been explored in the context of AL, specifically in the low-budget regime. In this work, we evaluate how foundation models influence three critical components of effective AL, namely, 1) initial labeled pool selection, 2) ensuring diverse sampling, and 3) the trade-off between representative and uncertainty sampling. We systematically study how the robust representations of foundation models (DINOv2, OpenCLIP) challenge existing findings in active learning. Our observations inform the principled construction of a new simple and elegant AL strategy that balances uncertainty estimated via dropout with sample diversity. We extensively test our strategy on many challenging image classification benchmarks, including natural images as well as out-of-domain biomedical images that are relatively understudied in the AL literature. We also provide a highly performant and efficient implementation of modern AL strategies (including our method) at https://github.com/sanketx/AL-foundation-models.

Vision systems to see and reason about the compositional nature of visual scenes are fundamental to understanding our world. The complex relations between objects and their locations, ambiguities, and variations in the real-world environment can be better described in human language, naturally governed by grammatical rules and other modalities such as audio and depth. The models learned to bridge the gap between such modalities coupled with large-scale training data facilitate contextual reasoning, generalization, and prompt capabilities at test time. These models are referred to as foundational models. The output of such models can be modified through human-provided prompts without retraining, e.g., segmenting a particular object by providing a bounding box, having interactive dialogues by asking questions about an image or video scene or manipulating the robot's behavior through language instructions. In this survey, we provide a comprehensive review of such emerging foundational models, including typical architecture designs to combine different modalities (vision, text, audio, etc), training objectives (contrastive, generative), pre-training datasets, fine-tuning mechanisms, and the common prompting patterns; textual, visual, and heterogeneous. We discuss the open challenges and research directions for foundational models in computer vision, including difficulties in their evaluations and benchmarking, gaps in their real-world understanding, limitations of their contextual understanding, biases, vulnerability to adversarial attacks, and interpretability issues. We review recent developments in this field, covering a wide range of applications of foundation models systematically and comprehensively. A comprehensive list of foundational models studied in this work is available at https://github.com/awaisrauf/Awesome-CV-Foundational-Models.

Recent vision foundation models can extract universal representations and show impressive abilities in various tasks. However, their application on object detection is largely overlooked, especially without fine-tuning them. In this work, we show that frozen foundation models can be a versatile feature enhancer, even though they are not pre-trained for object detection. Specifically, we explore directly transferring the high-level image understanding of foundation models to detectors in the following two ways. First, the class token in foundation models provides an in-depth understanding of the complex scene, which facilitates decoding object queries in the detector's decoder by providing a compact context. Additionally, the patch tokens in foundation models can enrich the features in the detector's encoder by providing semantic details. Utilizing frozen foundation models as plug-and-play modules rather than the commonly used backbone can significantly enhance the detector's performance while preventing the problems caused by the architecture discrepancy between the detector's backbone and the foundation model. With such a novel paradigm, we boost the SOTA query-based detector DINO from 49.0% AP to 51.9% AP (+2.9% AP) and further to 53.8% AP (+4.8% AP) by integrating one or two foundation models respectively, on the COCO validation set after training for 12 epochs with R50 as the detector's backbone.

Recent advances in foundational Vision Language Models (VLMs) have reshaped the evaluation paradigm in computer vision tasks. These foundational models, especially CLIP, have accelerated research in open-vocabulary computer vision tasks, including Open-Vocabulary Semantic Segmentation (OVSS). Although the initial results are promising, the dense prediction capabilities of VLMs still require further improvement. In this study, we enhance the semantic segmentation performance of CLIP by introducing new modules and modifications: 1) architectural changes in the last layer of ViT and the incorporation of attention maps from the middle layers with the last layer, 2) Image Engineering: applying data augmentations to enrich input image representations, and 3) using Large Language Models (LLMs) to generate definitions and synonyms for each class name to leverage CLIP's open-vocabulary capabilities. Our training-free method, ITACLIP, outperforms current state-of-the-art approaches on segmentation benchmarks such as COCO-Stuff, COCO-Object, Pascal Context, and Pascal VOC. Our code is available at https://github.com/m-arda-aydn/ITACLIP.

Human pose estimation methods work well on isolated people but struggle with multiple-bodies-in-proximity scenarios. Previous work has addressed this problem by conditioning pose estimation by detected bounding boxes or keypoints, but overlooked instance masks. We propose to iteratively enforce mutual consistency of bounding boxes, instance masks, and poses. The introduced BBox-Mask-Pose (BMP) method uses three specialized models that improve each other's output in a closed loop. All models are adapted for mutual conditioning, which improves robustness in multi-body scenes. MaskPose, a new mask-conditioned pose estimation model, is the best among top-down approaches on OCHuman. BBox-Mask-Pose pushes SOTA on OCHuman dataset in all three tasks - detection, instance segmentation, and pose estimation. It also achieves SOTA performance on COCO pose estimation. The method is especially good in scenes with large instances overlap, where it improves detection by 39% over the baseline detector. With small specialized models and faster runtime, BMP is an effective alternative to large human-centered foundational models. Code and models are available on https://MiraPurkrabek.github.io/BBox-Mask-Pose.

The introduction of large, foundational models to computer vision has led to drastically improved performance on the task of semantic segmentation. However, these existing methods exhibit a large performance drop when testing on images degraded by weather conditions such as rain, fog, or snow. We introduce a general paired-training method that can be applied to all current foundational model architectures that leads to improved performance on images in adverse weather conditions. To this end, we create the WeatherProof Dataset, the first semantic segmentation dataset with accurate clear and adverse weather image pairs, which not only enables our new training paradigm, but also improves the evaluation of the performance gap between clear and degraded segmentation. We find that training on these paired clear and adverse weather frames which share an underlying scene results in improved performance on adverse weather data. With this knowledge, we propose a training pipeline which accentuates the advantages of paired-data training using consistency losses and language guidance, which leads to performance improvements by up to 18.4% as compared to standard training procedures.

Segmenting and recognizing diverse object parts is a crucial ability in applications spanning various computer vision and robotic tasks. While significant progress has been made in object-level Open-Vocabulary Semantic Segmentation (OVSS), i.e., segmenting objects with arbitrary text, the corresponding part-level research poses additional challenges. Firstly, part segmentation inherently involves intricate boundaries, while limited annotated data compounds the challenge. Secondly, part segmentation introduces an open granularity challenge due to the diverse and often ambiguous definitions of parts in the open world. Furthermore, the large-scale vision and language models, which play a key role in the open vocabulary setting, struggle to recognize parts as effectively as objects. To comprehensively investigate and tackle these challenges, we propose an Open-Vocabulary Part Segmentation (OV-PARTS) benchmark. OV-PARTS includes refined versions of two publicly available datasets: Pascal-Part-116 and ADE20K-Part-234. And it covers three specific tasks: Generalized Zero-Shot Part Segmentation, Cross-Dataset Part Segmentation, and Few-Shot Part Segmentation, providing insights into analogical reasoning, open granularity and few-shot adapting abilities of models. Moreover, we analyze and adapt two prevailing paradigms of existing object-level OVSS methods for OV-PARTS. Extensive experimental analysis is conducted to inspire future research in leveraging foundational models for OV-PARTS. The code and dataset are available at https://github.com/OpenRobotLab/OV_PARTS.

Foundation models pretrained on large-scale datasets are revolutionizing the field of computational pathology (CPath). The generalization ability of foundation models is crucial for the success in various downstream clinical tasks. However, current foundation models have only been evaluated on a limited type and number of tasks, leaving their generalization ability and overall performance unclear. To address this gap, we established a most comprehensive benchmark to evaluate the performance of off-the-shelf foundation models across six distinct clinical task types, encompassing a total of 39 specific tasks. Our findings reveal that existing foundation models excel at certain task types but struggle to effectively handle the full breadth of clinical tasks. To improve the generalization of pathology foundation models, we propose a unified knowledge distillation framework consisting of both expert and self knowledge distillation, where the former allows the model to learn from the knowledge of multiple expert models, while the latter leverages self-distillation to enable image representation learning via local-global alignment. Based on this framework, a Generalizable Pathology Foundation Model (GPFM) is pretrained on a large-scale dataset consisting of 190 million images from around 86,000 public H&E whole slides across 34 major tissue types. Evaluated on the established benchmark, GPFM achieves an impressive average rank of 1.36, with 29 tasks ranked 1st, while the the second-best model, UNI, attains an average rank of 2.96, with only 4 tasks ranked 1st. The superior generalization of GPFM demonstrates its exceptional modeling capabilities across a wide range of clinical tasks, positioning it as a new cornerstone for feature representation in CPath.

Robust and accurate segmentation of scenes has become one core functionality in various visual recognition and navigation tasks. This has inspired the recent development of Segment Anything Model (SAM), a foundation model for general mask segmentation. However, SAM is largely tailored for single-modal RGB images, limiting its applicability to multi-modal data captured with widely-adopted sensor suites, such as LiDAR plus RGB, depth plus RGB, thermal plus RGB, etc. We develop MM-SAM, an extension and expansion of SAM that supports cross-modal and multi-modal processing for robust and enhanced segmentation with different sensor suites. MM-SAM features two key designs, namely, unsupervised cross-modal transfer and weakly-supervised multi-modal fusion, enabling label-efficient and parameter-efficient adaptation toward various sensor modalities. It addresses three main challenges: 1) adaptation toward diverse non-RGB sensors for single-modal processing, 2) synergistic processing of multi-modal data via sensor fusion, and 3) mask-free training for different downstream tasks. Extensive experiments show that MM-SAM consistently outperforms SAM by large margins, demonstrating its effectiveness and robustness across various sensors and data modalities.

Powered by large-scale pre-training, vision foundation models exhibit significant potential in open-world image understanding. However, unlike large language models that excel at directly tackling various language tasks, vision foundation models require a task-specific model structure followed by fine-tuning on specific tasks. In this work, we present Matcher, a novel perception paradigm that utilizes off-the-shelf vision foundation models to address various perception tasks. Matcher can segment anything by using an in-context example without training. Additionally, we design three effective components within the Matcher framework to collaborate with these foundation models and unleash their full potential in diverse perception tasks. Matcher demonstrates impressive generalization performance across various segmentation tasks, all without training. For example, it achieves 52.7% mIoU on COCO-20^i with one example, surpassing the state-of-the-art specialist model by 1.6%. In addition, Matcher achieves 33.0% mIoU on the proposed LVIS-92^i for one-shot semantic segmentation, outperforming the state-of-the-art generalist model by 14.4%. Our visualization results further showcase the open-world generality and flexibility of Matcher when applied to images in the wild. Our code can be found at https://github.com/aim-uofa/Matcher.

This work addresses the task of zero-shot monocular depth estimation. A recent advance in this field has been the idea of utilising Text-to-Image foundation models, such as Stable Diffusion. Foundation models provide a rich and generic image representation, and therefore, little training data is required to reformulate them as a depth estimation model that predicts highly-detailed depth maps and has good generalisation capabilities. However, the realisation of this idea has so far led to approaches which are, unfortunately, highly inefficient at test-time due to the underlying iterative denoising process. In this work, we propose a different realisation of this idea and present PrimeDepth, a method that is highly efficient at test time while keeping, or even enhancing, the positive aspects of diffusion-based approaches. Our key idea is to extract from Stable Diffusion a rich, but frozen, image representation by running a single denoising step. This representation, we term preimage, is then fed into a refiner network with an architectural inductive bias, before entering the downstream task. We validate experimentally that PrimeDepth is two orders of magnitude faster than the leading diffusion-based method, Marigold, while being more robust for challenging scenarios and quantitatively marginally superior. Thereby, we reduce the gap to the currently leading data-driven approach, Depth Anything, which is still quantitatively superior, but predicts less detailed depth maps and requires 20 times more labelled data. Due to the complementary nature of our approach, even a simple averaging between PrimeDepth and Depth Anything predictions can improve upon both methods and sets a new state-of-the-art in zero-shot monocular depth estimation. In future, data-driven approaches may also benefit from integrating our preimage.

The reference-based object segmentation tasks, namely referring image segmentation (RIS), few-shot image segmentation (FSS), referring video object segmentation (RVOS), and video object segmentation (VOS), aim to segment a specific object by utilizing either language or annotated masks as references. Despite significant progress in each respective field, current methods are task-specifically designed and developed in different directions, which hinders the activation of multi-task capabilities for these tasks. In this work, we end the current fragmented situation and propose UniRef++ to unify the four reference-based object segmentation tasks with a single architecture. At the heart of our approach is the proposed UniFusion module which performs multiway-fusion for handling different tasks with respect to their specified references. And a unified Transformer architecture is then adopted for achieving instance-level segmentation. With the unified designs, UniRef++ can be jointly trained on a broad range of benchmarks and can flexibly complete multiple tasks at run-time by specifying the corresponding references. We evaluate our unified models on various benchmarks. Extensive experimental results indicate that our proposed UniRef++ achieves state-of-the-art performance on RIS and RVOS, and performs competitively on FSS and VOS with a parameter-shared network. Moreover, we showcase that the proposed UniFusion module could be easily incorporated into the current advanced foundation model SAM and obtain satisfactory results with parameter-efficient finetuning. Codes and models are available at https://github.com/FoundationVision/UniRef.

The deep learning field is converging towards the use of general foundation models that can be easily adapted for diverse tasks. While this paradigm shift has become common practice within the field of natural language processing, progress has been slower in computer vision. In this paper we attempt to address this issue by investigating the transferability of various state-of-the-art foundation models to medical image classification tasks. Specifically, we evaluate the performance of five foundation models, namely SAM, SEEM, DINOv2, BLIP, and OpenCLIP across four well-established medical imaging datasets. We explore different training settings to fully harness the potential of these models. Our study shows mixed results. DINOv2 consistently outperforms the standard practice of ImageNet pretraining. However, other foundation models failed to consistently beat this established baseline indicating limitations in their transferability to medical image classification tasks.

Foundation models have revolutionized artificial intelligence (AI), offering remarkable capabilities across multi-modal domains. Their ability to precisely locate objects in complex aerial and satellite images, using rich contextual information and detailed object descriptions, is essential for remote sensing (RS). These models can associate textual descriptions with object positions through the Visual Grounding (VG) task, but due to domain-specific challenges, their direct application to RS produces sub-optimal results. To address this, we applied Parameter Efficient Fine Tuning (PEFT) techniques to adapt these models for RS-specific VG tasks. Specifically, we evaluated LoRA placement across different modules in Grounding DINO and used BitFit and adapters to fine-tune the OFA foundation model pre-trained on general-purpose VG datasets. This approach achieved performance comparable to or surpassing current State Of The Art (SOTA) models while significantly reducing computational costs. This study highlights the potential of PEFT techniques to advance efficient and precise multi-modal analysis in RS, offering a practical and cost-effective alternative to full model training.

The Segment Anything Model (SAM) stands as a foundational framework for image segmentation. While it exhibits remarkable zero-shot generalization in typical scenarios, its advantage diminishes when applied to specialized domains like medical imagery and remote sensing. To address this limitation, this paper introduces Conv-LoRA, a simple yet effective parameter-efficient fine-tuning approach. By integrating ultra-lightweight convolutional parameters into Low-Rank Adaptation (LoRA), Conv-LoRA can inject image-related inductive biases into the plain ViT encoder, further reinforcing SAM's local prior assumption. Notably, Conv-LoRA not only preserves SAM's extensive segmentation knowledge but also revives its capacity of learning high-level image semantics, which is constrained by SAM's foreground-background segmentation pretraining. Comprehensive experimentation across diverse benchmarks spanning multiple domains underscores Conv-LoRA's superiority in adapting SAM to real-world semantic segmentation tasks.

Large Language Models (LLMs) demonstrate strong capabilities in broad knowledge representation, yet they are inherently deficient in pixel-level perceptual understanding. Although the Segment Anything Model (SAM) represents a significant advancement in visual-prompt-driven image segmentation, it exhibits notable limitations in multi-mask prediction and category-specific segmentation tasks, and it cannot integrate all segmentation tasks within a unified model architecture. To address these limitations, we present X-SAM, a streamlined Multimodal Large Language Model (MLLM) framework that extends the segmentation paradigm from segment anything to any segmentation. Specifically, we introduce a novel unified framework that enables more advanced pixel-level perceptual comprehension for MLLMs. Furthermore, we propose a new segmentation task, termed Visual GrounDed (VGD) segmentation, which segments all instance objects with interactive visual prompts and empowers MLLMs with visual grounded, pixel-wise interpretative capabilities. To enable effective training on diverse data sources, we present a unified training strategy that supports co-training across multiple datasets. Experimental results demonstrate that X-SAM achieves state-of-the-art performance on a wide range of image segmentation benchmarks, highlighting its efficiency for multimodal, pixel-level visual understanding. Code is available at https://github.com/wanghao9610/X-SAM.

We aim to develop a robust yet flexible visual foundation model for Earth observation. It should possess strong capabilities in recognizing and localizing diverse visual targets while providing compatibility with various input-output interfaces required across different task scenarios. Current systems cannot meet these requirements, as they typically utilize task-specific architecture trained on narrow data domains with limited semantic coverage. Our study addresses these limitations from two aspects: data and modeling. We first introduce an automatic data engine that enjoys significantly better scalability compared to previous human annotation or rule-based approaches. It has enabled us to create the largest dataset of its kind to date, comprising 270K image-text-mask triplets covering an unprecedented range of diverse semantic categories and attribute specifications. Based on this data foundation, we further propose a task unification paradigm that centers around referring expression segmentation. It effectively handles a wide range of vision-centric perception tasks, including classification, detection, segmentation, grounding, etc, using a single model without any task-specific heads. Combining these innovations on data and modeling, we present RemoteSAM, a foundation model that establishes new SoTA on several earth observation perception benchmarks, outperforming other foundation models such as Falcon, GeoChat, and LHRS-Bot with significantly higher efficiency. Models and data are publicly available at https://github.com/1e12Leon/RemoteSAM.

Active contour models have achieved prominent success in the area of image segmentation, allowing complex objects to be segmented from the background for further analysis. Existing models can be divided into region-based active contour models and edge-based active contour models. However, both models use direct image data to achieve segmentation and face many challenging problems in terms of the initial contour position, noise sensitivity, local minima and inefficiency owing to the in-homogeneity of image intensities. The saliency map of an image changes the image representation, making it more visual and meaningful. In this study, we propose a novel model that uses the advantages of a saliency map with local image information (LIF) and overcomes the drawbacks of previous models. The proposed model is driven by a saliency map of an image and the local image information to enhance the progress of the active contour models. In this model, the saliency map of an image is first computed to find the saliency driven local fitting energy. Then, the saliency-driven local fitting energy is combined with the LIF model, resulting in a final novel energy functional. This final energy functional is formulated through a level set formulation, and regulation terms are added to evolve the contour more precisely across the object boundaries. The quality of the proposed method was verified on different synthetic images, real images and publicly available datasets, including medical images. The image segmentation results, and quantitative comparisons confirmed the contour initialization independence, noise insensitivity, and superior segmentation accuracy of the proposed model in comparison to the other segmentation models.

We present Franca (pronounced Fran-ka): free one; the first fully open-source (data, code, weights) vision foundation model that matches and in many cases surpasses the performance of state-of-the-art proprietary models, e.g., DINOv2, CLIP, SigLIPv2, etc. Our approach is grounded in a transparent training pipeline inspired by Web-SSL and uses publicly available data: ImageNet-21K and a subset of ReLAION-2B. Beyond model release, we tackle critical limitations in SSL clustering methods. While modern models rely on assigning image features to large codebooks via clustering algorithms like Sinkhorn-Knopp, they fail to account for the inherent ambiguity in clustering semantics. To address this, we introduce a parameter-efficient, multi-head clustering projector based on nested Matryoshka representations. This design progressively refines features into increasingly fine-grained clusters without increasing the model size, enabling both performance and memory efficiency. Additionally, we propose a novel positional disentanglement strategy that explicitly removes positional biases from dense representations, thereby improving the encoding of semantic content. This leads to consistent gains on several downstream benchmarks, demonstrating the utility of cleaner feature spaces. Our contributions establish a new standard for transparent, high-performance vision models and open a path toward more reproducible and generalizable foundation models for the broader AI community. The code and model checkpoints are available at https://github.com/valeoai/Franca.

Multi-modality foundation models, as represented by GPT-4V, have brought a new paradigm for low-level visual perception and understanding tasks, that can respond to a broad range of natural human instructions in a model. While existing foundation models have shown exciting potentials on low-level visual tasks, their related abilities are still preliminary and need to be improved. In order to enhance these models, we conduct a large-scale subjective experiment collecting a vast number of real human feedbacks on low-level vision. Each feedback follows a pathway that starts with a detailed description on the low-level visual appearance (*e.g. clarity, color, brightness* of an image, and ends with an overall conclusion, with an average length of 45 words. The constructed **Q-Pathway** dataset includes 58K detailed human feedbacks on 18,973 images with diverse low-level appearance. Moreover, to enable foundation models to robustly respond to diverse types of questions, we design a GPT-participated conversion to process these feedbacks into diverse-format 200K instruction-response pairs. Experimental results indicate that the **Q-Instruct** consistently elevates low-level perception and understanding abilities across several foundational models. We anticipate that our datasets can pave the way for a future that general intelligence can perceive, understand low-level visual appearance and evaluate visual quality like a human. Our dataset, model zoo, and demo is published at: https://q-future.github.io/Q-Instruct.

Foundation models are predominantly trained in an unsupervised or self-supervised manner on highly diverse and large-scale datasets, making them broadly applicable to various downstream tasks. In this work, we investigate for the first time whether such models are suitable for the specific domain of face recognition. We further propose and demonstrate the adaptation of these models for face recognition across different levels of data availability. Extensive experiments are conducted on multiple foundation models and datasets of varying scales for training and fine-tuning, with evaluation on a wide range of benchmarks. Our results indicate that, despite their versatility, pre-trained foundation models underperform in face recognition compared to similar architectures trained specifically for this task. However, fine-tuning foundation models yields promising results, often surpassing models trained from scratch when training data is limited. Even with access to large-scale face recognition training datasets, fine-tuned foundation models perform comparably to models trained from scratch, but with lower training computational costs and without relying on the assumption of extensive data availability. Our analysis also explores bias in face recognition, with slightly higher bias observed in some settings when using foundation models.

Foundation models have triggered a paradigm shift in computer vision and are increasingly being adopted in remote sensing, particularly for multispectral imagery. Yet, their potential in hyperspectral imaging (HSI) remains untapped due to the absence of comprehensive and globally representative hyperspectral datasets. To close this gap, we introduce SpectralEarth, a large-scale multi-temporal dataset designed to pretrain hyperspectral foundation models leveraging data from the Environmental Mapping and Analysis Program (EnMAP). SpectralEarth comprises 538,974 image patches covering 415,153 unique locations from more than 11,636 globally distributed EnMAP scenes spanning two years of archive. Additionally, 17.5% of these locations include multiple timestamps, enabling multi-temporal HSI analysis. Utilizing state-of-the-art self-supervised learning (SSL) algorithms, we pretrain a series of foundation models on SpectralEarth. We integrate a spectral adapter into classical vision backbones to accommodate the unique characteristics of HSI. In tandem, we construct four downstream datasets for land-cover and crop-type mapping, providing benchmarks for model evaluation. Experimental results support the versatility of our models, showcasing their generalizability across different tasks and sensors. We also highlight computational efficiency during model fine-tuning. The dataset, models, and source code will be made publicly available.

Foundation models encompass an extensive knowledge base and offer remarkable transferability. However, this knowledge becomes outdated or insufficient over time. The challenge lies in continuously updating foundation models to accommodate novel information while retaining their original capabilities. Leveraging the fact that foundation models have initial knowledge on various tasks and domains, we propose a novel approach that, instead of updating all parameters equally, localizes the updates to a sparse set of parameters relevant to the task being learned. We strike a balance between efficiency and new task performance, while maintaining the transferability and generalizability of foundation models. We extensively evaluate our method on foundational vision-language models with a diverse spectrum of continual learning tasks. Our method achieves improvements on the accuracy of the newly learned tasks up to 7% while preserving the pretraining knowledge with a negligible decrease of 0.9% on a representative control set accuracy.

Computer vision foundation models, such as DINO or OpenCLIP, are trained in a self-supervised manner on large image datasets. Analogously, substantial evidence suggests that the human visual system (HVS) is influenced by the statistical distribution of colors and patterns in the natural world, characteristics also present in the training data of foundation models. The question we address in this paper is whether foundation models trained on natural images mimic some of the low-level characteristics of the human visual system, such as contrast detection, contrast masking, and contrast constancy. Specifically, we designed a protocol comprising nine test types to evaluate the image encoders of 45 foundation and generative models. Our results indicate that some foundation models (e.g., DINO, DINOv2, and OpenCLIP), share some of the characteristics of human vision, but other models show little resemblance. Foundation models tend to show smaller sensitivity to low contrast and rather irregular responses to contrast across frequencies. The foundation models show the best agreement with human data in terms of contrast masking. Our findings suggest that human vision and computer vision may take both similar and different paths when learning to interpret images of the real world. Overall, while differences remain, foundation models trained on vision tasks start to align with low-level human vision, with DINOv2 showing the closest resemblance.

The robust association of the same objects across video frames in complex scenes is crucial for many applications, especially Multiple Object Tracking (MOT). Current methods predominantly rely on labeled domain-specific video datasets, which limits the cross-domain generalization of learned similarity embeddings. We propose MASA, a novel method for robust instance association learning, capable of matching any objects within videos across diverse domains without tracking labels. Leveraging the rich object segmentation from the Segment Anything Model (SAM), MASA learns instance-level correspondence through exhaustive data transformations. We treat the SAM outputs as dense object region proposals and learn to match those regions from a vast image collection. We further design a universal MASA adapter which can work in tandem with foundational segmentation or detection models and enable them to track any detected objects. Those combinations present strong zero-shot tracking ability in complex domains. Extensive tests on multiple challenging MOT and MOTS benchmarks indicate that the proposed method, using only unlabeled static images, achieves even better performance than state-of-the-art methods trained with fully annotated in-domain video sequences, in zero-shot association. Project Page: https://matchinganything.github.io/

Following its success for vision and text, the "foundation model" (FM) paradigm -- pretraining large models on massive data, then fine-tuning on target tasks -- has rapidly expanded to domains in the sciences, engineering, healthcare, and beyond. Has this achieved what the original FMs accomplished, i.e. the supplanting of traditional supervised learning in their domains? To answer we look at three modalities -- genomics, satellite imaging, and time series -- with multiple recent FMs and compare them to a standard supervised learning workflow: model development, hyperparameter tuning, and training, all using only data from the target task. Across these three specialized domains, we find that it is consistently possible to train simple supervised models -- no more complicated than a lightly modified wide ResNet or UNet -- that match or even outperform the latest foundation models. Our work demonstrates that the benefits of large-scale pretraining have yet to be realized in many specialized areas, reinforces the need to compare new FMs to strong, well-tuned baselines, and introduces two new, easy-to-use, open-source, and automated workflows for doing so.

The CLIP and Segment Anything Model (SAM) are remarkable vision foundation models (VFMs). SAM excels in segmentation tasks across diverse domains, while CLIP is renowned for its zero-shot recognition capabilities. This paper presents an in-depth exploration of integrating these two models into a unified framework. Specifically, we introduce the Open-Vocabulary SAM, a SAM-inspired model designed for simultaneous interactive segmentation and recognition, leveraging two unique knowledge transfer modules: SAM2CLIP and CLIP2SAM. The former adapts SAM's knowledge into the CLIP via distillation and learnable transformer adapters, while the latter transfers CLIP knowledge into SAM, enhancing its recognition capabilities. Extensive experiments on various datasets and detectors show the effectiveness of Open-Vocabulary SAM in both segmentation and recognition tasks, significantly outperforming the naive baselines of simply combining SAM and CLIP. Furthermore, aided with image classification data training, our method can segment and recognize approximately 22,000 classes.

Foundation models have emerged as a promising approach in time series forecasting (TSF). Existing approaches either fine-tune large language models (LLMs) or build large-scale time-series datasets to develop TSF foundation models. However, these methods face challenges due to the severe cross-domain gap or in-domain heterogeneity. In this paper, we explore a new road to building a TSF foundation model from rich and high-quality natural images, based on the intrinsic similarities between images and time series. To bridge the gap between the two domains, we reformulate the TSF task as an image reconstruction task, which is further processed by a visual masked autoencoder (MAE) self-supervised pre-trained on the ImageNet dataset. Surprisingly, without further adaptation in the time-series domain, the proposed VisionTS could achieve superior zero-shot forecasting performance compared to existing TSF foundation models. With minimal fine-tuning, VisionTS could further improve the forecasting and achieve state-of-the-art performance in most cases. These findings suggest that visual models could be a free lunch for TSF and highlight the potential for future cross-domain research between computer vision and TSF. Our code is publicly available at https://github.com/Keytoyze/VisionTS.