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<!DOCTYPE html>
<html lang="es">
<head>
  <meta charset="UTF-8">
  <meta name="viewport" content="width=device-width, initial-scale=1.0">
  <title>Ecosistema Académico Global en Biotecnología</title>
  <style>
    @import url('https://fonts.googleapis.com/css2?family=Poppins:wght@300;400;600;700&display=swap');

    body {
      margin: 0;
      padding: 0;
      display: flex;
      justify-content: center;
      align-items: center;
      height: 100vh;
      background-color: #f0f2f5;
      font-family: 'Poppins', sans-serif;
    }

    .slide {
      width: 1280px;
      height: 720px;
      background: linear-gradient(135deg, #e0f7fa 0%, #f0f4c3 100%);
      display: flex;
      flex-direction: column;
      overflow: hidden;
      position: relative;
      box-shadow: 0 10px 30px rgba(0,0,0,0.1);
      animation: fadeIn 1s ease-in-out;
    }

    @keyframes fadeIn {
      from { opacity: 0; transform: scale(0.95); }
      to { opacity: 1; transform: scale(1); }
    }

    .header {
      padding: 20px 50px;
      text-align: center;
      color: #003366;
      border-bottom: 2px solid rgba(0, 83, 156, 0.1);
    }

    .header h1 {
      font-size: 36px;
      margin: 0;
      font-weight: 700;
    }

    .header h2 {
      font-size: 18px;
      margin: 5px 0 0;
      font-weight: 400;
      color: #00539c;
    }

    .main-content {
      display: grid;
      grid-template-columns: repeat(4, 1fr);
      grid-template-rows: auto auto;
      gap: 15px;
      padding: 20px;
      flex-grow: 1;
    }

    .region-card {
      background-color: rgba(255, 255, 255, 0.8);
      border-radius: 12px;
      padding: 15px;
      border: 1px solid rgba(0,0,0,0.05);
      box-shadow: 0 4px 12px rgba(0,0,0,0.05);
      transition: transform 0.3s ease, box-shadow 0.3s ease;
    }

    .region-card:hover {
        transform: translateY(-5px);
        box-shadow: 0 8px 20px rgba(0,0,0,0.1);
    }

    .region-card h3 {
      margin: 0 0 10px 0;
      font-size: 16px;
      font-weight: 600;
      display: flex;
      align-items: center;
      border-bottom: 2px solid;
      padding-bottom: 8px;
    }
    
    .region-card h3 .icon {
        width: 20px;
        height: 20px;
        margin-right: 8px;
    }

    .region-card ul {
      margin: 0;
      padding-left: 20px;
      font-size: 13px;
      color: #333;
    }

    .region-card ul li {
      margin-bottom: 6px;
      line-height: 1.4;
    }
    
    .region-card ul li::marker {
        font-size: 1.2em;
    }

    #ecuador { grid-column: 1 / 2; grid-row: 1 / 2; border-left: 5px solid #FFC107; }
    #ecuador h3 { color: #D4A000; border-color: #FFC107; }
    #latam { grid-column: 2 / 3; grid-row: 1 / 2; border-left: 5px solid #28A745; }
    #latam h3 { color: #1E7E34; border-color: #28A745; }
    #global { grid-column: 1 / 2; grid-row: 2 / 3; border-left: 5px solid #007BFF; }
    #global h3 { color: #0056B3; border-color: #007BFF; }
    #apac { grid-column: 2 / 3; grid-row: 2 / 3; border-left: 5px solid #DC3545; }
    #apac h3 { color: #B02A37; border-color: #DC3545; }

    .map-container {
      grid-column: 3 / 5;
      grid-row: 1 / 3;
      display: flex;
      justify-content: center;
      align-items: center;
      position: relative;
    }

    #world-map {
      width: 100%;
      height: auto;
    }

    #world-map .land {
        fill: #b2dfdb; /* Light teal for land */
        stroke: #ffffff;
        stroke-width: 0.5;
    }

    .map-marker {
        fill: rgba(220, 53, 69, 0.8); /* Red marker */
        stroke: white;
        stroke-width: 0.5px;
        animation: pulse 2s infinite;
        cursor: pointer;
    }
    
    .map-marker-usa { fill: rgba(0, 123, 255, 0.8); } /* Blue for USA */
    .map-marker-eu { fill: rgba(0, 123, 255, 0.8); } /* Blue for Europe */
    .map-marker-latam { fill: rgba(40, 167, 69, 0.8); } /* Green for Latam */
    .map-marker-apac { fill: rgba(220, 53, 69, 0.8); } /* Red for APAC */
    .map-marker-ecu { fill: rgba(255, 193, 7, 0.9); } /* Yellow for Ecuador */


    @keyframes pulse {
      0% { r: 3; opacity: 1; }
      50% { r: 6; opacity: 0.5; }
      100% { r: 3; opacity: 1; }
    }

    .footer {
      display: grid;
      grid-template-columns: 1fr 1.5fr;
      gap: 20px;
      padding: 0 20px 20px 20px;
      align-items: stretch;
    }

    .conclusion-box, .factors-box, .flow-box {
      background-color: rgba(255, 255, 255, 0.8);
      border-radius: 12px;
      padding: 15px;
      border: 1px solid rgba(0,0,0,0.05);
      box-shadow: 0 4px 12px rgba(0,0,0,0.05);
    }
    
    .bottom-container {
        grid-column: 1 / 5;
        display: flex;
        gap: 15px;
        align-items: stretch;
    }

    .flow-box {
        flex: 2;
        border-top: 5px solid #6f42c1;
    }
    .flow-chart {
        display: flex;
        justify-content: space-around;
        align-items: center;
        height: 100%;
    }
    .flow-item {
        text-align: center;
        color: #6f42c1;
        font-weight: 600;
    }
    .flow-item .icon {
        width: 40px;
        height: 40px;
        margin-bottom: 5px;
        fill: #6f42c1;
    }
    .flow-arrow {
        font-size: 30px;
        color: #6f42c1;
        font-weight: bold;
        opacity: 0.5;
    }

    .conclusion-box {
        flex: 1.5;
        border-top: 5px solid #17a2b8;
        display: flex;
        flex-direction: column;
        justify-content: center;
    }
    .conclusion-box h4 {
        margin: 0 0 5px 0;
        font-size: 16px;
        color: #0f6674;
    }
    .conclusion-box p {
        margin: 0;
        font-size: 16px;
        font-style: italic;
        text-align: center;
        color: #0f6674;
        font-weight: 600;
    }

    .factors-box {
        flex: 1.5;
        border-top: 5px solid #fd7e14;
    }
    .factors-box h4 {
        margin: 0 0 10px 0;
        font-size: 16px;
        color: #c4610f;
    }
    .factors-box ul {
        margin: 0;
        padding-left: 20px;
        font-size: 13px;
        color: #333;
        list-style-type: '✓ ';
    }
    .factors-box ul li {
        margin-bottom: 2px;
    }
  </style>
</head>
<body>
  <div class="slide">
    <div class="header">
      <h1>Ecosistema Académico Global en Biotecnología</h1>
      <h2>Base educativa como fundamento del desarrollo industrial</h2>
    </div>

    <div class="main-content">
      <div class="region-card" id="ecuador">
        <h3><svg class="icon" viewBox="0 0 24 24"><path fill="currentColor" d="M12,3L1,9L12,15L21,10.09V17H23V9L12,3M5,10.18L12,13.72L19,10.18L12,6.63L5,10.18Z" /></svg>Ecuador</h3>
        <ul>
          <li>11+ universidades con programas consolidados</li>
          <li>Fortaleza en formación pero brecha de transferencia</li>
          <li>Potencial para COBIEC como catalizador</li>
        </ul>
      </div>

      <div class="region-card" id="latam">
        <h3><svg class="icon" viewBox="0 0 24 24"><path fill="currentColor" d="M12,2C6.48,2 2,6.48 2,12s4.48,10 10,10s10,-4.48 10,-10S17.52,2 12,2zM13,12c0,3.31 -2.69,6 -6,6c-0.34,0 -0.67,-0.03 -1,-0.08C6.32,14.26 8.94,12 12,12c0.34,0 0.67,0.03 1,0.08c-0.32,3.72 -3.26,6.66 -7,6.92C3.18,17.43 2,14.86 2,12c0,-2.03 0.63,-3.9 1.69,-5.43C5.63,7.5 8.5,10.43 8.08,14c0.33,-0.05 0.66,-0.08 1,-0.08c3.31,0 6,-2.69 6,-6c0.34,0 0.67,0.03 1,0.08c-0.42,-3.57 2.2,-6.3 5.31,-6.63C16.37,3.63 14.03,6 11,6c-0.34,0 -0.67,-0.03 -1,-0.08c0.32,-3.72 3.26,-6.66 7,-6.92C19.82,4.57 22,8.14 22,12c0,2.03 -0.63,3.9 -1.69,5.43c-1.92,-0.92 -3.5,-2.59 -4.31,-4.5C14.5,10.43 11.5,7.5 11.92,4c-0.33,0.05 -0.66,0.08 -1,0.08C7.69,4 5,6.69 5,10c0,-0.34 -0.03,-0.67 -0.08,-1C8.74,8.68 12,5.45 12,2z" /></svg>Líderes Regionales: América Latina</h3>
        <ul>
          <li><b>Brasil:</b> Líder regional con ecosistema robusto</li>
          <li><b>México:</b> Base académica sólida y sector industrial creciente</li>
          <li><b>Argentina:</b> Modelo provincial avanzado (Colegio Santafesino)</li>
        </ul>
      </div>

      <div class="region-card" id="global">
        <h3><svg class="icon" viewBox="0 0 24 24"><path fill="currentColor" d="M12,2A10,10 0 0,0 2,12A10,10 0 0,0 12,22A10,10 0 0,0 22,12A10,10 0 0,0 12,2Z" /></svg>Potencias Globales</h3>
        <ul>
          <li><b>EE.UU.:</b> MIT, Harvard, Stanford - Ecosistema integrado</li>
          <li><b>Reino Unido:</b> Cambridge, Oxford - Excelencia investigativa</li>
          <li><b>Suiza:</b> ETH Zurich - Modelo de alta eficiencia</li>
          <li><b>Alemania:</b> Sistema descentralizado de BioRegions</li>
        </ul>
      </div>

      <div class="region-card" id="apac">
        <h3><svg class="icon" viewBox="0 0 24 24"><path fill="currentColor" d="M17.65,6.35C16.2,4.9 14.21,4 12,4A8,8 0 0,0 4,12A8,8 0 0,0 12,20C15.73,20 18.84,17.45 19.73,14H17.65C16.83,16.33 14.61,18 12,18A6,6 0 0,1 6,12A6,6 0 0,1 12,6C13.66,6 15.14,6.69 16.22,7.78L13,11H20V4L17.65,6.35Z" /></svg>Asia-Pacífico Emergente</h3>
        <ul>
          <li><b>Japón:</b> U. de Tokio - Biotecnología médica</li>
          <li><b>Corea del Sur:</b> U. Nacional de Seúl - Liderazgo en patentes</li>
          <li><b>Australia:</b> Melbourne, Queensland - Crecimiento acelerado</li>
        </ul>
      </div>

      <div class="map-container">
        <svg id="world-map" viewBox="0 0 1000 500">
            <path class="land" d="M632.5 425.8l-5.6-3.8-2.3-4.2-2.3-4.2-3.4-3.8-2.3-4.2-3.1-3.8-2.3-4.2-2.3-4.2-3.1-3.8-2.3-4.2-2.3-4.2-3.4-3.8-3.1-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-4.2-2.3-4.2-3.1-3.8-3.4-3.8-2.3-