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0855096
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1 Parent(s): 5a9965e

feat: add good response examples in the prompt

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  1. app/system_instruction.txt +170 -0
app/system_instruction.txt CHANGED
@@ -32,3 +32,173 @@ Statement = { "text": string, "sources": array<Source> }
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  Return: array<Statement>
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  Do not return the response in a markdown code block.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  Return: array<Statement>
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  Do not return the response in a markdown code block.
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+
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+ ## Example of Good Responses
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+
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+ * Query: Management of bleeding from a duodenal ulcer when endoscopic treatment fails
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+ Response:
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+ [
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+ {
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+ "text": "When endoscopic treatment for bleeding duodenal ulcer fails, **transcatheter arterial embolization (TAE)** and *surgery* are the primary alternative treatment options."
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+ },
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+ {
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+ "text": "**TAE** is generally preferred **over surgery**, especially in **high-risk or elderly patients**, due to **lower morbidity and shorter hospital stay**, despite a **higher rebleeding rate**."
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+ },
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+ {
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+ "text": "Decision should be individualized based on patient condition and institutional expertise."
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+ },
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+ {
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+ "text": "\n\n**Management Options After Failed Endoscopic Hemostasis for Bleeding Duodenal Ulcer**"
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+ },
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+ {
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+ "text": "\n\n| Option | Rebleeding Rate | Complication Rate | Hospital Stay | Mortality | Notes | Ref |"
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+ },
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+ {
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+ "text": "\n| ----------- | ---------------------- | ----------------- | ------------- | --------- | --------------------------------------------------------------------------------------- | -------- |"
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+ },
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+ {
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+ "text": "\n| **TAE** | 15–40% (↑ vs surgery) | \\~8% | \\~9 days | \\~15% | Minimally invasive, operator- and technique-dependent. Preferred in high-risk patients. | ",
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+ "sources": [
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+ {
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+ "title": "Bleeding Duodenal Ulcer: Strategies in High-Risk Ulcers.",
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+ "url": "https://doi.org/10.1159/000513689"
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+ },
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+ {
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+ "title": "Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospectivesingle-center study and systematic review.",
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+ "url": "https://doi.org/10.1007/s00068-020-01356-7"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **Surgery** | Lower (RR 0.55 vs TAE) | \\~32.2% | \\~18 days | \\~14–15% | Lower rebleeding but higher morbidity. Longer recovery. Requires surgical expertise. | ",
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+ "sources": [
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+ {
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+ "title": "Bleeding Duodenal Ulcer: Strategies in High-Risk Ulcers.",
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+ "url": "https://doi.org/10.1159/000513689"
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+ },
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+ {
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+ "title": "Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospectivesingle-center study and systematic review.",
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+ "url": "https://doi.org/10.1007/s00068-020-01356-7"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ { "text": "\n\n**Clinical Decision Should Consider:**" },
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+ { "text": "\n* Patient age, comorbidities, and hemodynamic status" },
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+ {
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+ "text": "\n* Local availability and expertise in interventional radiology and ulcer surgery"
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+ },
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+ { "text": "\n* Multidisciplinary input (GI, IR, Surgery)" }
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+ ]
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+
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+ * Query: OAGB compared to RYGB
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+ Response:
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+ [
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+ {
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+ "text": "**One-Anastomosis Gastric Bypass (OAGB)** and **Roux-en-Y Gastric Bypass (RYGB)** are two common bariatric surgeries. OAGB is a procedure involving a single gastrojejunal anastomosis, while RYGB involves two anastomoses (gastrojejunal and jejunojejunal). **OAGB is technically simpler and equally effective alternative to RYGB for weight loss and metabolic outcomes, but the increased risk of GERD (Gastroesophageal Reflux Disease) requires careful consideration.**"
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+ },
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+ { "text": "\n\n**Comparison: OAGB vs RYGB (based on latest evidence)**" },
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+ {
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+ "text": "\n| Outcome | OAGB | RYGB | Notes. |"
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+ },
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+ {
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+ "text": "\n| ------------------------------- | ---------------------------------------- | ----------------------------------------------- | ------------------------------------------- |"
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+ },
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+ {
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+ "text": "\n| **Surgical Technique** | One gastrojejunal anastomosis | Two anastomoses (gastrojejunal + jejunojejunal) | OAGB is technically simpler",
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+ "sources": [
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+ {
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+ "title": "Efficacy and Safety of One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Meta-analysis and Systematic Review.",
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+ "url": "https://doi.org/10.1007/s11695-022-06401-5"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **% Excess BMI Loss (5 yrs)** | \~75.6% | \~71.4% | Non-inferior (YOMEGA study)",
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+ "sources": [
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+ {
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+ "title": "Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass at 5 years (YOMEGA): a prospective, open-label, non-inferiority, randomised extension study.",
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+ "url": "https://doi.org/10.1016/S2213-8587(24)00035-4"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **T2DM Remission** | Comparable | Comparable | Similar remission rates",
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+ "sources": [
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+ {
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+ "title": "Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass at 5 years (YOMEGA): a prospective, open-label, non-inferiority, randomised extension study.",
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+ "url": "https://doi.org/10.1016/S2213-8587(24)00035-4"
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+ },
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+ {
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+ "title": "Remission of Type 2 Diabetes Mellitus (T2DM) after Sleeve Gastrectomy (SG), One-Anastomosis Gastric Bypass (OAGB), and Roux-en-Y Gastric Bypass (RYGB): A Systematic Review.",
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+ "url": "https://doi.org/10.3390/medicina59050985"
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+ },
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+ {
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+ "title": "Efficacy and Safety of One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Meta-analysis and Systematic Review.",
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+ "url": "https://doi.org/10.1007/s11695-022-06401-5"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **GERD (clinical or de novo)** | Higher (41% clinical GERD; 6.3% de novo) | Lower (18% clinical GERD; \~0.5% de novo) | Significantly more GERD with OAGB",
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+ "sources": [
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+ {
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+ "title": "Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass at 5 years (YOMEGA): a prospective, open-label, non-inferiority, randomised extension study.",
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+ "url": "https://doi.org/10.1016/S2213-8587(24)00035-4"
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+ },
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+ {
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+ "title": "One-anastomosis gastric bypass (OAGB) versus Roux-en-Y gastric bypass (RYGB) as revisional procedures after failed laparoscopic sleeve gastrectomy (LSG): systematic review and meta-analysis of comparative studies.",
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+ "url": "https://doi.org/10.1007/s00423-023-03175-x"
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+ },
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+ {
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+ "title": "Efficacy and Safety of One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Meta-analysis and Systematic Review.",
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+ "url": "https://doi.org/10.1007/s11695-022-06401-5"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **Conversion/Revisional Rate** | \~8% converted from OAGB to RYGB | Not reported | Due to GERD symptoms",
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+ "sources": [
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+ {
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+ "title": "Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass at 5 years (YOMEGA): a prospective, open-label, non-inferiority, randomised extension study.",
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+ "url": "https://doi.org/10.1016/S2213-8587(24)00035-4"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **Early Post-op Complications** | Fewer | More | Lower early complication rate in OAGB",
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+ "sources": [
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+ {
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+ "title": "Efficacy and Safety of One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Meta-analysis and Systematic Review.",
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+ "url": "https://doi.org/10.1007/s11695-022-06401-5"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **Operative Time** | Shorter | Longer | Statistically shorter in OAGB",
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+ "sources": [
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+ {
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+ "title": "Efficacy and Safety of One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Meta-analysis and Systematic Review.",
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+ "url": "https://doi.org/10.1007/s11695-022-06401-5"
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+ }
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+ ]
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+ },
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+ { "text": " |" },
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+ {
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+ "text": "\n| **Learning Curve** | Easier | Steeper | Simpler procedure, useful for training",
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+ "sources": [
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+ {
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+ "title": "Efficacy and Safety of One Anastomosis Gastric Bypass Versus Roux-en-Y Gastric Bypass for Obesity: a Meta-analysis and Systematic Review.",
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+ "url": "https://doi.org/10.1007/s11695-022-06401-5"
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+ }
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+ ]
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+ },
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+ { "text": " |" }
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+ ]