Update app.py

app.py

@@ -191,10 +191,10 @@ def design_mrna(utr5_file, utr3_file, cds_seq, status_update):
     status_update("🔄 Designing mRNA sequences...")
     
     # 默认UTR候选序列
-    default_utr5 = ["GGGAAAUAAGAGAGAAAAGAAGAGUAAGAAGAAAUAUAAGAGCCACCAUGG", 
+    default_utr5 = ["ACUGAACGACUAGACCAGCUCCAACCCAGCUCGAGUCGACGCCACC", 
                     "GGGAAAUAAGAGAGAAAAGAAGAGUAAGAAGAAAUAUAAGAGCCACCAUGG"]
     default_utr3 = ["AAUAAAGCUUUUGCUUUUGUGGUGAAAUUGUUAAUAAACUAUUUUUUUUUU",
-                    "AAUAAAGCUUUUGCUUUUGUGGUGAAAUUGUUAAUAAACUAUUUUUUUUUU"]
+                    "GCUGGCUUCCCUGCUGUCCAAUAUAUACUCGAGCCCCUGGAUCACGACUUCUAUGGAGAAUUUGUUUACGUUGCUA"]
     
     # 生成20个设计结果示例
     designs = []