Update app.py

app.py

@@ -82,8 +82,26 @@ def _query_pubmed(query: str, email: Optional[str] = PUBMED_EMAIL) -> Optional[D
         "retmode": "json",
         "email": email
     }
-    return _query_api(API_ENDPOINTS["pubmed"], params)
+    data = _query_api(API_ENDPOINTS["pubmed"], params)
+    if data and 'esearchresult' in data:
+         return data
+    else:
+        return None
 
+def _safe_get(endpoint: str, params: Optional[Dict] = None):
+    """Safely fetches data from an API."""
+    try:
+        response = requests.get(endpoint, params=params)
+        response.raise_for_status()  # Raises HTTPError for bad responses
+        return response.json()
+    except requests.exceptions.HTTPError as http_err:
+        st.error(f"HTTP error occurred: {http_err}")
+        logging.error(f"HTTP error occurred: {http_err}")
+        return None
+    except Exception as err:
+        st.error(f"Other error occurred: {err}")
+        logging.error(f"Other error occurred: {err}")
+        return None
 
 def _get_pubchem_smiles(drug_name: str) -> Optional[str]:
     """Retrieves SMILES from PubChem, returns None on failure."""
@@ -159,12 +177,12 @@ def _analyze_adverse_events(drug_name: str, api_key:Optional[str] = OPENFDA_KEY,
 
 def _get_pharmgkb_data(gene:str) -> Optional[Dict]:
     """Fetches pharmacogenomic data from PharmGKB."""
-    url = API_ENDPOINTS["pharmgkb"].format(gene)
+    url = f"https://api.pharmgkb.org/v1/data/variant/{gene}/clinicalAnnotations"
     data = _query_api(url)
     if data and 'clinicalAnnotations' in data:
          return data
     else:
-        return None
+         return None
 
 def _get_bioportal_data(ontology: str, term: str) -> Optional[Dict]:
     """Fetches data from BioPortal."""