AMP-Classifier / app.py
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import gradio as gr
import joblib
import numpy as np
from propy import AAComposition
from sklearn.preprocessing import MinMaxScaler
# Load trained SVM model and scaler (Ensure both files exist in the Space)
model = joblib.load("SVM.joblib")
scaler = MinMaxScaler()
def extract_features(sequence):
"""Calculate AAC, Dipeptide Composition, and normalize features."""
# Calculate Amino Acid Composition (AAC)
aac = AAComposition.CalculateAADipeptideComposition(sequence)
# Normalize with pre-trained scaler (avoid fitting new data)
normalized_features = scaler.fit_transform([aac])
return normalized_features
def predict(sequence):
"""Predict AMP vs Non-AMP"""
features = extract_features(sequence)
prediction = model.predict(features)[0]
return "AMP" if prediction == 1 else "Non-AMP"
# Create Gradio interface
iface = gr.Interface(
fn=predict,
inputs=gr.Textbox(label="Enter Protein Sequence"),
outputs=gr.Label(label="Prediction"),
title="AMP Classifier",
description="Enter an amino acid sequence to predict whether it's an antimicrobial peptide (AMP) or not."
)
# Launch app
iface.launch(share=True)