Update app.py

app.py

@@ -3,225 +3,719 @@ import openai
 import fitz  # PyMuPDF for PDF processing
 import os
 import tempfile
+import time
+import logging
+import re
+from typing import List, Optional, Dict, Any, Union
+import markdown
+import concurrent.futures
+
+# Set up logging
+logging.basicConfig(
+    level=logging.INFO,
+    format='%(asctime)s - %(name)s - %(levelname)s - %(message)s'
+)
+logger = logging.getLogger(__name__)
 
 # Variable to store API key
 api_key = ""
 
 # Function to update API key
-def set_api_key(key):
+def set_api_key(key: str) -> str:
+    """Set the OpenAI API key."""
     global api_key
-    api_key = key
-    return "API Key Set Successfully!"
+    if not key.strip():
+        return "Please enter a valid API key"
+    
+    api_key = key.strip()
+    return "✅ API Key Set Successfully!"
 
 # Function to extract text from PDF
-def extract_text_from_pdf(pdf_path):
+def extract_text_from_pdf(pdf_path: str) -> str:
+    """Extract text content from a PDF file."""
     try:
         doc = fitz.open(pdf_path)
-        text = "\n".join([page.get_text("text") for page in doc])
+        text = ""
+        for page_num, page in enumerate(doc):
+            text += f"\n--- Page {page_num + 1} ---\n"
+            text += page.get_text("text")
         return text
     except Exception as e:
+        logger.error(f"Error extracting text from PDF: {str(e)}")
         return f"Error extracting text from PDF: {str(e)}"
 
-# Function to interact with OpenAI API for systematic review
-def generate_systematic_review(pdf_files, review_question, include_tables=True):
-    if not api_key:
-        return "Please enter your OpenAI API key first."
-    
-    if not pdf_files:
-        return "Please upload at least one PDF file."
+# Function to truncate text to fit token limits
+def truncate_text_for_tokens(text: str, max_tokens: int = 8000) -> str:
+    """Truncate text to approximately fit within token limits."""
+    # Rough approximation: 1 token ≈ 4 characters in English
+    char_limit = max_tokens * 4
+    if len(text) > char_limit:
+        return text[:char_limit] + "\n[Content truncated due to length...]"
+    return text
+
+# Function to extract title from PDF content
+def extract_title(pdf_text: str) -> str:
+    """Attempt to extract a title from PDF text."""
+    # Look for title in first few lines
+    first_lines = pdf_text.split('\n')[:10]
+    for line in first_lines:
+        line = line.strip()
+        # Title candidates: all caps, longer than 5 chars, shorter than 200
+        if len(line) > 5 and len(line) < 200 and not line.startswith('---'):
+            return line
     
-    if not review_question:
-        return "Please enter a review question."
+    return "Untitled Document"
+
+# Model selection options
+MODEL_OPTIONS = {
+    "gpt-4.1": "GPT-4 (Most powerful, slower)",
+    "gpt-3.5-turbo": "GPT-3.5 Turbo (Faster, less powerful)"
+}
+
+# Function to get available OpenAI models
+def get_available_models() -> List[str]:
+    """Get list of available OpenAI models."""
+    if not api_key:
+        return list(MODEL_OPTIONS.keys())
     
     try:
         openai.api_key = api_key
+        response = openai.Model.list()
+        models = [model.id for model in response['data'] if 'gpt' in model.id.lower()]
+        # Add to our options if found
+        for model in models:
+            if model not in MODEL_OPTIONS and ('gpt-4.1' in model or 'gpt-3.5-turbo' in model):
+                MODEL_OPTIONS[model] = model
+        return list(MODEL_OPTIONS.keys())
+    except Exception as e:
+        logger.error(f"Error fetching models: {str(e)}")
+        return list(MODEL_OPTIONS.keys())
+
+# Function for parallel PDF processing
+def process_pdf_in_parallel(pdf_files: List[str]) -> List[tuple]:
+    """Process multiple PDFs in parallel to extract text."""
+    results = []
+    
+    with concurrent.futures.ThreadPoolExecutor() as executor:
+        future_to_pdf = {executor.submit(extract_text_from_pdf, pdf_path): pdf_path for pdf_path in pdf_files}
+        for future in concurrent.futures.as_completed(future_to_pdf):
+            pdf_path = future_to_pdf[future]
+            pdf_name = os.path.basename(pdf_path)
+            try:
+                pdf_text = future.result()
+                # Truncate if needed
+                pdf_text = truncate_text_for_tokens(pdf_text)
+                results.append((pdf_name, pdf_text))
+            except Exception as e:
+                logger.error(f"Error processing {pdf_name}: {str(e)}")
+                results.append((pdf_name, f"Error processing file: {str(e)}"))
+    
+    return results
+
+# Function to create system prompt
+def create_system_prompt(review_type: str = "systematic") -> str:
+    """Create system prompt based on review type."""
+    if review_type == "systematic":
+        return """
+        You are an expert academic researcher tasked with creating comprehensive systematic reviews. Follow these steps:
         
-        # Create the system message with systematic review guidelines
-        system_prompt = """
         Step 1: Identify a Research Field
-        The first step in writing a systematic review paper is to identify a research field. This involves selecting a specific area of study that you are interested in and want to explore further.
+        Identify the specific area of study represented in the provided papers.
         
         Step 2: Generate a Research Question
-        Once you have identified your research field, the next step is to generate a research question. This question should be specific, measurable, achievable, relevant, and time-bound (SMART).
+        Create a specific, measurable, achievable, relevant, and time-bound (SMART) research question that unifies the papers.
         
         Step 3: Create a Protocol
-        After generating your research question, the next step is to create a protocol. A detailed plan of how you will conduct your research, including the methods you will use, the data you will collect, and the analysis you will perform.
+        Outline a detailed methodology for your review, including analysis methods appropriate for the papers.
         
         Step 4: Evaluate Relevant Literature
-        The fourth step is to evaluate relevant literature. This involves searching for and reviewing existing studies related to your research question. You should critically evaluate the quality of these studies and identify any gaps or limitations in the current literature.
+        Critically evaluate the quality, methodology, and findings of the provided papers, identifying gaps or limitations.
         
         Step 5: Investigate Sources for Answers
-        The fifth step is to investigate sources for answers. This involves searching for and accessing relevant data and information that will help you answer your research question.
+        Examine how the papers contribute to answering the research question.
         
         Step 6: Collect Data as per Protocol
-        The sixth step is to collect data as per protocol. This involves implementing the methods outlined in your protocol and collecting the data specified. You should ensure that your data collection methods are rigorous and reliable.
+        Implement rigorous data collection methods, extracting key findings and statistics.
         
         Step 7: Data Extraction
-        The seventh step is to extract the data. This involves organizing and analyzing the data you have collected, and extracting the relevant information that will help you answer your research question.
+        Organize the extracted data in a structured format, including tables where appropriate.
         
         Step 8: Critical Analysis of Results
-        The eighth step is to conduct a critical analysis of your results. This involves interpreting your findings, identifying patterns and trends, and drawing conclusions based on your data.
+        Interpret patterns, trends, and conclusions from the data, comparing findings across papers.
         
         Step 9: Interpreting Derivations
-        The ninth step is to interpret the derivations. This involves taking the conclusions you have drawn from your data and interpreting them in the context of your research question.
+        Contextualize the findings in relation to the research question and broader field.
         
         Step 10: Concluding Statements
-        The final step is to make concluding statements. This involves summarizing your findings and drawing conclusions based on your research. You should also provide recommendations for future research and implications for practice.
+        Summarize findings, draw conclusions, and provide recommendations for future research.
+        
+        Step 11: References
+        Include proper citations for all papers reviewed and any additional references.
         
-        Step-11:
-        Please include references in the form of citation and also link to the reference papers.
+        Your review should be:
+        - Comprehensive yet concise
+        - Well-structured with clear headings and subheadings
+        - Using academic language appropriate for a scholarly audience
+        - Including data visualizations or tables where helpful
+        - Balanced and objective in evaluating the evidence
         """
+    elif review_type == "literature":
+        return """
+        You are an expert academic researcher tasked with creating a thorough literature review. Your review should:
         
-        # Extract text from each PDF
-        pdf_texts = []
-        pdf_names = []
+        1. Provide an overview of the current state of knowledge in the specific field
+        2. Identify common themes, methodologies, and findings across the papers
+        3. Highlight contradictions or inconsistencies in the literature
+        4. Evaluate the strength of evidence for key claims
+        5. Identify research gaps and future directions
+        6. Organize findings in a logical, thematic structure
+        7. Include visual elements (tables, concept maps) to synthesize information
+        8. Maintain academic rigor and proper attribution
         
-        for pdf_file in pdf_files:
-            if isinstance(pdf_file, str):  # If it's already a path
-                pdf_path = pdf_file
-            else:  # If it's a file object
-                pdf_path = pdf_file.name
-                
-            pdf_name = os.path.basename(pdf_path)
-            pdf_text = extract_text_from_pdf(pdf_path)
-            
-            pdf_texts.append(pdf_text)
-            pdf_names.append(pdf_name)
+        Your review should be scholarly in tone, well-organized, and provide a balanced assessment of the literature.
+        """
+    else:  # meta-analysis
+        return """
+        You are an expert researcher conducting a meta-analysis of the provided papers. Your analysis should:
+        
+        1. Identify a precise research question that can be answered quantitatively
+        2. Extract comparable quantitative data, effect sizes, or statistics from the papers
+        3. Assess the methodological quality and risk of bias in each study
+        4. Synthesize findings using appropriate statistical methods
+        5. Present results using forest plots, funnel plots, or other visualizations
+        6. Discuss heterogeneity and its potential sources
+        7. Evaluate publication bias and its impact on the findings
+        8. Draw conclusions based on the pooled data
+        9. Discuss implications for practice and future research
+        
+        Your meta-analysis should follow PRISMA guidelines where applicable, maintain statistical rigor, and provide clear visual representations of the quantitative synthesis.
+        """
+
+# Function to interact with OpenAI API for systematic review
+def generate_systematic_review(
+    pdf_files: List[str], 
+    review_question: str,
+    model: str = "gpt-4.1",
+    review_type: str = "systematic",
+    include_tables: bool = True,
+    temperature: float = 0.7,
+    max_tokens: int = 4000
+) -> str:
+    """Generate a systematic review of the provided PDF files."""
+    if not api_key:
+        return "Please enter your OpenAI API key first."
+    
+    if not pdf_files:
+        return "Please upload at least one PDF file."
+    
+    if not review_question:
+        return "Please enter a review question."
+    
+    try:
+        # Start timer
+        start_time = time.time()
+        
+        openai.api_key = api_key
+        
+        # Create the system message with review guidelines
+        system_prompt = create_system_prompt(review_type)
+        
+        # Process PDFs in parallel
+        logger.info(f"Processing {len(pdf_files)} PDFs...")
+        pdf_results = process_pdf_in_parallel(pdf_files)
+        
+        # Extract titles for reference
+        titles = [extract_title(pdf_text) for _, pdf_text in pdf_results]
+        pdf_names = [name for name, _ in pdf_results]
         
         # Prepare the user prompt with the review question and instructions
         table_instruction = ""
         if include_tables:
-            table_instruction = " Please include important new generated tables in your review."
+            table_instruction = " Please include important tables, charts or figures in your review to help summarize the findings."
             
-        user_prompt = f"Please generate a systematic review of the following {len(pdf_files)} papers: {', '.join(pdf_names)}.{table_instruction}\n\nReview Question: {review_question}"
+        user_prompt = f"""
+        Please generate a {review_type} review of the following {len(pdf_files)} papers:
+        {', '.join([f"{i+1}. {pdf_names[i]} (Title: {titles[i]})" for i in range(len(pdf_names))])}
+        
+        Review Question: {review_question}
+        
+        {table_instruction}
+        
+        Format your response with clear headings, subheadings, and properly formatted tables using markdown syntax.
+        """
+        
+        # Combine PDF texts, with truncation if needed
+        combined_pdf_text = ""
+        total_chars = 0
+        max_chars = 20000  # Rough approximation to fit within token limits
+        
+        for i, (pdf_name, pdf_text) in enumerate(pdf_results):
+            header = f"\n\n--- PAPER {i+1}: {pdf_name} ---\n\n"
+            if total_chars + len(header) + len(pdf_text) > max_chars:
+                # Truncate this paper's text
+                remaining = max_chars - total_chars - len(header)
+                if remaining > 500:  # Only add if we can include meaningful content
+                    truncated_text = pdf_text[:remaining] + "\n[... Content truncated due to length limitations ...]"
+                    combined_pdf_text += header + truncated_text
+                    total_chars += len(header) + len(truncated_text)
+                break
+            else:
+                combined_pdf_text += header + pdf_text
+                total_chars += len(header) + len(pdf_text)
         
         # Create the messages for the API call
         messages = [
             {"role": "system", "content": system_prompt},
-            {"role": "user", "content": user_prompt + "\n\n" + "\n\n".join([f"Paper {i+1} - {pdf_names[i]}:\n{pdf_texts[i]}" for i in range(len(pdf_texts))])}
+            {"role": "user", "content": user_prompt + combined_pdf_text}
         ]
         
-        # Call the API with temperature=1 and top_p=1 as specified
+        logger.info(f"Sending request to OpenAI API (model: {model})...")
+        
+        # Call the API
         response = openai.ChatCompletion.create(
-            model="gpt-4.1",
+            model=model,
             messages=messages,
-            temperature=1,
-            top_p=1,
-            max_tokens=2048
+            temperature=temperature,
+            max_tokens=max_tokens
         )
         
-        return response["choices"][0]["message"]["content"]
+        result = response["choices"][0]["message"]["content"]
+        
+        # Convert markdown to HTML for tables
+        result_html = markdown.markdown(result, extensions=['tables'])
+        
+        # Calculate time taken
+        time_taken = time.time() - start_time
+        logger.info(f"Review generated in {time_taken:.2f} seconds")
+        
+        return result
     
     except Exception as e:
+        logger.error(f"Error generating review: {str(e)}")
         return f"Error generating systematic review: {str(e)}"
 
 # Function to save uploaded files
-def save_uploaded_files(files):
+def save_uploaded_files(files) -> List[str]:
+    """Save uploaded files to temporary directory and return their paths."""
     if not files:
         return []
     
     saved_paths = []
     for file in files:
         if file is not None:
+            # Extract file extension
+            file_extension = os.path.splitext(file.name)[1].lower()
+            
+            # Only process PDF files
+            if file_extension != '.pdf':
+                continue
+                
             # Create a temporary file
-            with tempfile.NamedTemporaryFile(delete=False, suffix=".pdf") as tmp_file:
-                tmp_file.write(file)
+            with tempfile.NamedTemporaryFile(delete=False, suffix=file_extension) as tmp_file:
+                # If file is a file object, write its content
+                if hasattr(file, 'read'):
+                    tmp_file.write(file.read())
+                # If file is already a path
+                else:
+                    with open(file, 'rb') as f:
+                        tmp_file.write(f.read())
+                        
                 saved_paths.append(tmp_file.name)
     
     return saved_paths
 
-# Gradio UI Layout
-with gr.Blocks() as demo:
-    gr.Markdown("# Systematic Review Generator for Research Papers")
-    
-    with gr.Accordion("How to Use This App", open=True):
-        gr.Markdown("""
-        ### Getting Started:
-        1. Enter your OpenAI API key in the field below and click "Set API Key"
-        2. Upload multiple PDF research papers (2 or more recommended)
-        3. Enter your review question or topic
-        4. Check the "Include Tables" option if you want the review to include comparison tables
-        5. Click "Generate Systematic Review" to start the process
-        
-        ### Tips:
-        - For best results, upload papers that are related to the same research topic or field
-        - Be specific in your review question to get more focused results
-        - The generated review will follow a systematic structure including research field identification, data extraction, analysis, and conclusions
-        - The more papers you upload, the more comprehensive the review will be
-        """)
-    
-    # API Key Input
-    with gr.Row():
-        api_key_input = gr.Textbox(label="Enter OpenAI API Key", type="password")
-        api_key_button = gr.Button("Set API Key", elem_id="api_key_button")
-        api_key_output = gr.Textbox(label="API Key Status", interactive=False)
-    
-    # PDF Upload and Review Settings
-    with gr.Row():
-        with gr.Column():
-            pdf_files = gr.File(label="Upload PDF Research Papers", file_count="multiple", type="binary")
-            review_question = gr.Textbox(label="Review Question or Topic", placeholder="What are the current advances in GAN applications for speech processing?")
-            include_tables = gr.Checkbox(label="Include Comparison Tables", value=True)
-            generate_button = gr.Button("Generate Systematic Review", elem_id="generate_button")
-        
-    # Output
-    review_output = gr.Textbox(label="Systematic Review", interactive=False, lines=20)
-    
-    # Button actions
-    api_key_button.click(set_api_key, inputs=[api_key_input], outputs=[api_key_output])
-    
-    # Generate systematic review
-    def process_files_and_generate_review(files, question, include_tables):
-        if not files:
-            return "Please upload at least one PDF file."
-        
-        # Save uploaded files
-        saved_paths = save_uploaded_files(files)
-        
-        # Generate review
-        review = generate_systematic_review(saved_paths, question, include_tables)
-        
-        # Clean up temporary files
-        for path in saved_paths:
-            try:
-                os.remove(path)
-            except:
-                pass
-        
-        return review
-    
-    generate_button.click(
-        process_files_and_generate_review, 
-        inputs=[pdf_files, review_question, include_tables], 
-        outputs=[review_output]
-    )
-
-# Add CSS styling
+# Custom HTML and CSS for better UI
 css = """
 <style>
+    /* Base styling */
+    body {
+        font-family: 'Inter', -apple-system, BlinkMacSystemFont, sans-serif;
+    }
+    
+    .container {
+        max-width: 1200px !important;
+        margin: 0 auto;
+    }
+    
+    /* Header styling */
+    .header {
+        background: linear-gradient(135deg, #4a00e0 0%, #8e2de2 100%);
+        color: white;
+        padding: 20px;
+        border-radius: 10px;
+        margin-bottom: 20px;
+        box-shadow: 0 4px 6px rgba(0, 0, 0, 0.1);
+    }
+    
+    /* Button styling */
     #generate_button {
         background: linear-gradient(135deg, #4a00e0 0%, #8e2de2 100%); /* Purple gradient */
         color: white;
         font-weight: bold;
+        padding: 10px 20px;
+        border-radius: 8px;
+        border: none;
+        cursor: pointer;
+        box-shadow: 0 2px 4px rgba(0, 0, 0, 0.2);
+        transition: all 0.3s ease;
     }
+    
     #generate_button:hover {
         background: linear-gradient(135deg, #5b10f1 0%, #9f3ef3 100%); /* Slightly lighter */
+        transform: translateY(-2px);
+        box-shadow: 0 4px 8px rgba(0, 0, 0, 0.2);
     }
+    
     #api_key_button {
         background: linear-gradient(135deg, #68d391 0%, #48bb78 100%); /* Green gradient */
         color: white;
         font-weight: bold;
         margin-top: 27px;
+        padding: 10px 20px;
+        border-radius: 8px;
+        border: none;
+        cursor: pointer;
+        box-shadow: 0 2px 4px rgba(0, 0, 0, 0.2);
+        transition: all 0.3s ease;
     }
+    
     #api_key_button:hover {
         background: linear-gradient(135deg, #38a169 0%, #68d391 100%); /* Slightly darker green */
+        transform: translateY(-2px);
+        box-shadow: 0 4px 8px rgba(0, 0, 0, 0.2);
+    }
+    
+    /* Card styling */
+    .card {
+        background-color: white;
+        border-radius: 10px;
+        padding: 20px;
+        margin-bottom: 20px;
+        box-shadow: 0 2px 4px rgba(0, 0, 0, 0.1);
+    }
+    
+    /* Form styling */
+    .form-group {
+        margin-bottom: 15px;
     }
+    
+    /* Tabs styling */
+    .tab-content {
+        padding: 20px;
+        background-color: white;
+        border-radius: 0 0 10px 10px;
+    }
+    
+    /* Table styling in output */
+    .output-container table {
+        border-collapse: collapse;
+        width: 100%;
+        margin: 20px 0;
+    }
+    
+    .output-container th, .output-container td {
+        border: 1px solid #ddd;
+        padding: 8px;
+        text-align: left;
+    }
+    
+    .output-container th {
+        background-color: #f2f2f2;
+        font-weight: bold;
+    }
+    
+    .output-container tr:nth-child(even) {
+        background-color: #f9f9f9;
+    }
+    
+    /* Spinner styling */
+    .loading-spinner {
+        display: inline-block;
+        width: 20px;
+        height: 20px;
+        border: 3px solid rgba(0, 0, 0, 0.1);
+        border-radius: 50%;
+        border-top-color: #4a00e0;
+        animation: spin 1s ease-in-out infinite;
+    }
+    
+    @keyframes spin {
+        to {
+            transform: rotate(360deg);
+        }
+    }
+    
+    /* Customizations for Gradio */
     .gradio-container {
         max-width: 1200px !important;
     }
+    
+    .gr-form, .gr-box {
+        border-radius: 10px !important;
+    }
+    
+    .gr-input, .gr-textarea {
+        border-radius: 6px !important;
+    }
+    
+    /* Responsive adjustments */
+    @media (max-width: 768px) {
+        .header {
+            padding: 15px;
+        }
+        
+        #generate_button, #api_key_button {
+            padding: 8px 16px;
+        }
+    }
 </style>
 """
 
+# Add custom HTML header
+header_html = """
+<div class="header">
+    <h1>Systematic Review Generator for Research Papers</h1>
+    <p>Upload multiple PDF papers to generate comprehensive reviews, literature analyses, and meta-analyses</p>
+</div>
+"""
+
+# Custom progress component
+def progress_component(text, progress):
+    return f"""
+    <div style="margin: 10px 0; width: 100%;">
+        <div style="display: flex; align-items: center; margin-bottom: 5px;">
+            <div>{text}</div>
+            <div style="margin-left: auto;">{progress}%</div>
+        </div>
+        <div style="background-color: #e0e0e0; height: 8px; border-radius: 4px; width: 100%;">
+            <div style="background: linear-gradient(135deg, #4a00e0 0%, #8e2de2 100%); height: 100%; width: {progress}%; border-radius: 4px;"></div>
+        </div>
+    </div>
+    """
+
+# Function to create a review
+def create_review(files, question, model, review_type, include_tables, temperature, max_tokens, progress=gr.Progress()):
+    try:
+        if not files:
+            return "Please upload at least one PDF file."
+        
+        progress(0.1, desc="Saving uploaded files...")
+        saved_paths = save_uploaded_files(files)
+        
+        if not saved_paths:
+            return "No valid PDF files were uploaded. Please upload PDF files only."
+        
+        progress(0.3, desc="Processing PDFs...")
+        review = generate_systematic_review(
+            saved_paths, 
+            question, 
+            model=model,
+            review_type=review_type,
+            include_tables=include_tables,
+            temperature=temperature,
+            max_tokens=max_tokens
+        )
+        
+        progress(0.9, desc="Finalizing review...")
+        
+        # Clean up temporary files
+        for path in saved_paths:
+            try:
+                os.remove(path)
+            except Exception as e:
+                logger.error(f"Error removing temporary file {path}: {str(e)}")
+        
+        progress(1.0, desc="Complete!")
+        return review
+    
+    except Exception as e:
+        logger.error(f"Error in create_review: {str(e)}")
+        return f"An error occurred: {str(e)}"
+
+# Gradio UI Layout
+def create_ui():
+    with gr.Blocks(css=css) as demo:
+        gr.HTML(header_html)
+        
+        with gr.Tabs() as tabs:
+            with gr.TabItem("Generate Review"):
+                with gr.Row():
+                    with gr.Column(scale=1):
+                        with gr.Box():
+                            gr.Markdown("### 1. Setup API Key")
+                            api_key_input = gr.Textbox(
+                                label="Enter OpenAI API Key", 
+                                type="password",
+                                placeholder="sk-..."
+                            )
+                            api_key_button = gr.Button("Set API Key", elem_id="api_key_button")
+                            api_key_output = gr.Textbox(
+                                label="API Key Status", 
+                                interactive=False,
+                                value="Not set"
+                            )
+                        
+                        with gr.Box():
+                            gr.Markdown("### 2. Upload Papers")
+                            pdf_files = gr.File(
+                                label="Upload PDF Research Papers (PDF files only)", 
+                                file_count="multiple", 
+                                type="binary",
+                                file_types=[".pdf"]
+                            )
+                    
+                    with gr.Column(scale=1):
+                        with gr.Box():
+                            gr.Markdown("### 3. Review Configuration")
+                            review_question = gr.Textbox(
+                                label="Review Question or Topic", 
+                                placeholder="What are the current advances in GAN applications for speech processing?",
+                                lines=2
+                            )
+                            
+                            review_type = gr.Radio(
+                                label="Review Type",
+                                choices=["systematic", "literature", "meta-analysis"],
+                                value="systematic"
+                            )
+                            
+                            model = gr.Dropdown(
+                                label="Model",
+                                choices=list(MODEL_OPTIONS.keys()),
+                                value="gpt-4.1"
+                            )
+                            
+                            with gr.Row():
+                                include_tables = gr.Checkbox(
+                                    label="Include Tables and Figures", 
+                                    value=True
+                                )
+                                
+                                with gr.Column():
+                                    temperature = gr.Slider(
+                                        label="Temperature (Creativity)",
+                                        minimum=0.0,
+                                        maximum=1.0,
+                                        value=0.7,
+                                        step=0.1
+                                    )
+                            
+                            max_tokens = gr.Slider(
+                                label="Maximum Output Length",
+                                minimum=1000,
+                                maximum=8000,
+                                value=4000,
+                                step=500
+                            )
+                            
+                            generate_button = gr.Button(
+                                "Generate Review", 
+                                elem_id="generate_button",
+                                variant="primary"
+                            )
+                
+                # Output
+                with gr.Box():
+                    gr.Markdown("### Review Output")
+                    review_output = gr.Markdown(
+                        label="Generated Review",
+                        value="Review will appear here after generation..."
+                    )
+                    
+                    with gr.Row():
+                        copy_button = gr.Button("📋 Copy to Clipboard")
+                        export_button = gr.Button("📥 Export as Markdown")
+            
+            with gr.TabItem("How to Use"):
+                gr.Markdown("""
+                ### Getting Started with the Systematic Review Generator
+
+                #### 1. Setting Up
+                - Enter your OpenAI API key in the field provided and click "Set API Key"
+                - You'll need an API key with access to GPT-4 or GPT-3.5 for best results
+                - Your API key is never stored and is only used for this session
+
+                #### 2. Uploading Papers
+                - Upload 2 or more PDF research papers (the more related they are, the better)
+                - Only PDF files are supported
+                - Papers should ideally be related to the same research field
+
+                #### 3. Configuring Your Review
+                - Enter a specific review question or topic
+                - Choose the review type:
+                  - **Systematic Review**: Follows a rigorous methodology to answer a specific research question
+                  - **Literature Review**: Provides an overview of existing research on a topic
+                  - **Meta-Analysis**: Combines and analyzes quantitative data from multiple studies
+                - Select the AI model (GPT-4 recommended for complex papers)
+                - Adjust temperature (higher = more creative, lower = more focused)
+                - Set maximum output length (longer reviews will be more comprehensive)
+
+                #### 4. Generating Your Review
+                - Click "Generate Review" to start the process
+                - Processing time depends on the number and size of papers, and the selected model
+                - You can copy or export the final review when complete
+
+                #### Tips for Best Results
+                - Use papers from the same field or on related topics
+                - Be specific in your review question
+                - For technical papers, choose GPT-4 for better comprehension
+                - The system works best with 2-5 related papers
+                - Consider using a lower temperature (0.3-0.5) for more factual reviews
+                """)
+                
+            with gr.TabItem("About"):
+                gr.Markdown("""
+                ### About the Systematic Review Generator
+
+                This application helps researchers, students, and academics generate comprehensive reviews of scientific papers. It leverages advanced AI to analyze PDF research papers and synthesize findings into structured, coherent reviews.
+
+                #### Features
+                - Support for multiple review types: systematic reviews, literature reviews, and meta-analyses
+                - Automatic extraction of text from PDF files
+                - Parallel processing of multiple papers
+                - Integration with OpenAI's GPT models
+                - Customizable output parameters
+                - Table and figure generation capabilities
+
+                #### How It Works
+                1. The system extracts text from your uploaded PDFs
+                2. It identifies the main topics, methodologies, and findings
+                3. Based on your review question, it synthesizes information across papers
+                4. It structures the information following academic review standards
+                5. It provides a comprehensive review with proper sections and references
+
+                #### Limitations
+                - The quality of the review depends on the clarity of the PDFs and their text extraction
+                - Complex scientific notation, tables, or images in PDFs may not be perfectly interpreted
+                - The system provides a starting point, not a final paper - always review and verify the output
+                - Token limits may prevent full analysis of very long or numerous papers
+
+                #### Privacy & Security
+                - Your API key is never stored and is only used for the current session
+                - Uploaded PDFs are processed temporarily and deleted after review generation
+                - No data is retained after you close the application
+                """)
+
+        # Button actions
+        api_key_button.click(set_api_key, inputs=[api_key_input], outputs=[api_key_output])
+        
+        generate_button.click(
+            create_review, 
+            inputs=[pdf_files, review_question, model, review_type, include_tables, temperature, max_tokens], 
+            outputs=[review_output]
+        )
+        
+        # Function to refresh model list
+        def refresh_models():
+            return gr.Dropdown.update(choices=get_available_models())
+        
+        api_key_button.click(refresh_models, outputs=[model])
+        
+        # Copy function is handled client-side via JavaScript
+        
+    return demo
+
 # Launch the app
 if __name__ == "__main__":
+    demo = create_ui()
     demo.launch(share=True)