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history\tof\tbariatric\tsurgery\tmay\tbe\tless\twilling\tto\tgain\tenough\tweight\tafter\thaving\tinvested\tso\tmuch\nin\tlosing\tit,\tso\tguidance\twith\treassurance\tand\tsupport\tmay\tbe\tnecessary\n\t(see\t\nChapter\t20\n).\tAlthough\nthe\tweight\tgain\tguidelines\tare\tbased\ton\tprepregnant\tBMI\tand\tare\tthe\tsame\tas\tfor\tthose\twithout
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surgery,\tthey\tare\tdifficult\tto\tachieve\tfor\tthese\twomen.\tFocus\ton\thigh\tnutrient,\tlow\tvolume\tfoods\tand\nminimize\tthe\tintake\tof\tfoods\tthat\tdon’t\thelp\tfetal\tgrowth\tor\tdevelopment.\nThese\twomen\tneed\tto\tbe\tmonitored\tcarefully\tduring\tpregnancy\tand\ttheir\tprenatal\tcare\tmay\tneed\nto\tbe
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to\tbe\n\tmodified.\tPractitioners\tshould\thave\ta\thigh\tdegree\tof\tsuspicion\twhen\thearing\tabout\ndiscomforts.\tThe\tgastric\tband\tcan\tslip,\tcausing\tan\tobstruction\tthat\tcan\tmimic\thyperemesis\tbut\tcan\nresult\tin\tfetal\tdeath\t(\nJacquemyn\tand\tMeesters,\t2014\n).\tThis\tband\tmigration\tcan\thappen\tyears\tafter
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experience\thigher,\tshorter\tglucose\tpeaks\tand\tlower\tlows,\nidentification\tof\ta\tproblem\tmay\tbe\tmissed\tif\tthe\tcommon\t2-hour\twindow\tis\tused\t(\nBonis\tet\tal,\t2016\n;\nFeichtinger\tet\tal,\t2017\n).\nEarlier\tresearch\tfound\tlittle\tor\tno\tdifference\tin\tpregnancy\toutcomes\tafter\tbariatric\tsurgery\tbut
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studies\twere\tsmall,\tshort\tterm,\tand\thad\tinconsistent\tresults.\tNewer\tstudies\tare\tlarger\tand\thave\nmatched\tcontrols,\tenabling\n\tresearchers\tto\tbetter\tcharacterize\tthe\tadditional\trisk\tfor\tpregnancy\tafter\nbariatric\tsurgery,\ttaking\tinto\taccount\tthe\televated\trisk\tof\tcontinued\tobesity.\tWomen\twho\thave\thad
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-0.0034977723844349384, -0.033430684357881546, -0.029151225462555885, 0.10008244961500168, 0.051375098526477814, -0.056602757424116135, -0.0376751683652401, 0.02778203971683979, -0.0008010733290575445, -0.0726221576333046, -0.049521151930093765, 0.07067203521728516, -0.00795906875282526, -0.05527045205235481, -0.015182523988187313, 0.06169380247592926, 0.06463207304477692, 0.00837052334100008, -0.032375603914260864, 0.04383498802781105, -0.015479039400815964, 0.046003490686416626, 0.07105353474617004, 0.010015021078288555 ]
describe\tthe\tconsequences\tof\tspecific\tnutrient\tdeficiencies,\tincluding\tvitamins\tK,\tB\n12\n,\tand\tA.\nThe\testimation\tof\tnutritional\trisk\tfrom\tbariatric\tsurgery\thas\trisen\tover\ttime,\tas\tevidenced\tby\tthe\nincreased\tnumber\tof\tnutrients\tbeing\tmonitored,\tthe\ttesting\tfrequency,\n\tand\tthe\tlevel\tof\troutine\nsupplementation\trecommended.\tCurrent\tguidelines\t(
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supplementation\trecommended.\tCurrent\tguidelines\t(\nParrott\tet\tal,\t2017\n)\tare\tnot\tspecific\tto\npregnancy\t(see\t\nChapter\t20\n).\tStudies\tregarding\tpregnancy\tfollowing\tbariatric\tsurgery\tare\tongoing\n(\nJans\tet\tal,\t2016\n),\tincluding\texamining\tthe\teffect\tof\tbariatric\tsurgery\ton\tbreastmilk\tcomposition,\tand
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0.02561044692993164, 0.09004726260900497, 0.0384211428463459, -0.029579348862171173, -0.02268088422715664, 0.03334122896194458, -0.009491114877164364, -0.06761705130338669, 0.022688107565045357, 0.06378749012947083, 0.004222193267196417, -0.06429768353700638, 0.03248986229300499, 0.03107498213648796, 0.07422590255737305, 0.046603355556726456, -0.01713605225086212, 0.02455979585647583, 0.03965340182185173, 0.09197252243757248, 0.07548101991415024, -0.050464361906051636 ]
recommendations\tbetter\tthan\tothers\tdo.\nMultiple\tbirths\nThe\tincidence\tof\tmultiple\tbirths\tin\tthe\tUnited\tStates\tis\trising\tbecause\tof\tthe\tincreased\tuse\tof\tfertility\ndrugs\tand\tART,\tage\tat\tconception,\tand\tobesity\trates\tamong\tpregnant\twomen\t(\nACOG,\t2016b\n).\nMultifetal\tgestations\tcause\tsignificant
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ACOG,\t2016b\n).\nMultifetal\tgestations\tcause\tsignificant\n\tmaternal\tphysiologic\tadaptations\tbeyond\tthe\tusual\tpregnancy\nchanges,\tincluding\tincreased\tplasma\tvolume,\tmetabolic\trate,\tand\tincreased\tinsulin\tresistance\n(\nGoodnight\tand\tNewman,\t2009\n).\nThese\tinfants\thave\ta\tgreater\trisk\tof\tpreterm\tdelivery\twith\taccompanying\tIUGR\tor\tLBW\tthan\tdo
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singletons.\tAdequate\tmaternal\tweight\tgain,\tespecially\tearly\tin\tpregnancy\t(before\t20\tweeks),\thas\nbeen\tshown\tto\tbe\tparticularly\n\timportant\tfor\toptimal\tgrowth\tand\ttime\tin-utero\t(\nGreenan\tet\tal,\t2017\n).\nA\tcommon\trule\tof\tthumb\tis\tto\ttarget\ta\t24-pound\tgain\tby\t24\tweeks\tof\tgestation\tfor\ttwins\t(\nGoodnight\nand\tNewman,\t2009
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Goodnight\nand\tNewman,\t2009\n)\tbut\tintervention\tshould\tbegin\tin\tthe\tfirst\ttrimester.\tThe\tIOM\tweight\tgain\nguidelines\tfor\ttwins\tare\tprovisional\t(see\t\nTable\t14.11\n\tand\t\nAppendix\t3\n)\tbut\tare\tsupported\tby\tmore\nrecent\tresearch\t(\nHutcheon\tet\tal,\t2018\n).\n\tThe\teffect\tof\tchorionicity\ton\toptimal\tweight\tgain\tis\tunknown.
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).\n\tThe\teffect\tof\tchorionicity\ton\toptimal\tweight\tgain\tis\tunknown.\nFor\tthose\tpregnant\twith\ttriplets\tor\tother\thigher-order\tmultiples,\tthere\tis\tlimited\tinformation\navailable,\tbut\tbest\tpractice\tadvice\tdoes\texist.\tTarget\ta\tgain\tof\tat\tleast\t36\tpounds\tby\t24\tweeks\tof\ngestation\tfor\ttriplets\t(\nStone\tand\tKohari,\t2015
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gestation\tfor\ttriplets\t(\nStone\tand\tKohari,\t2015\n).\tMean\tgestational\tweight\tgain\tfor\ttriplets\tis\t45\tto\t51\npounds\t(20.5\tto\t23\tkg)\tat\t32\tto\t34\tweeks.\n\tFor\tquadruplets,\tit\tis\t46\tto\t68\tpounds\t(20.8\tto\t31\tkg)\tat\t31\nto\t32\tweeks\t(\nRasmussen\tand\tYaktine,\t2009\n)\tbut\tbetter\toutcomes\thave\tbeen\tseen\twith\thigher\tgains\n(\nLuke\tet\tal,\t2017\n;\t\nLuke,\t2015\n).
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(\nLuke\tet\tal,\t2017\n;\t\nLuke,\t2015\n).\nThe\toptimal\tnutrient\trequirements\tfor\ttwins\tand\thigher-order\tmultiples\tare\tnot\tyet\tknown\tbut\tare\ncertainly\thigher\tthan\tfor\tsingleton\tpregnancies.\tThere\tare\tmore\tfetuses\tand\tmore\tplacentas\tneeding\nnourishment.\n\tIn\taddition,\tthe\tincreased\tmaternal\tweight\tmay\tincrease\tinflammation\tand\ttherefore
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negatively\taffect\tthe\tnutrient\ttransport\t(\nCao\tand\tO’Brien,\t2013\n).\tIt\tis\tassumed\tthat\tat\tleast\tthe\tmilk\nand\tmeat\tfood\tgroups\tneed\tto\tbe\tdoubled\tfor\ttwins,\tincreasing\tas\tneeded\tfor\toptimal\tfetal\tgrowth,\nwith\teven\thigher\tservings\tfor\tthe\thigher\torder\tmultiples\t(\nLuke\tet\tal,\t2017\n).\nA\tsummary\tof\tcurrent\tnutritional\tplans\n\tfor\ttwins\tis\tsummarized\tin
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ACOG,\t2013c\n).\tBecause\tof\ta\tgreater\tneed\tfor\tnutritional\ndensity\tin\tthe\tdiet,\tit\tis\trecommended\tthat\tonly\t40%\tof\tcalories\tcome\tfrom\tcarbohydrate,\twith\t20%\nfrom\tprotein,\tand\t40%\tfrom\tfat\t(\nGoodnight\tand\tNewman,\t2009\n).\tA\twoman\tpregnant\twith\tmultiples\nhas\tincreased\tnutrient\tneeds\tbut\tdecreased\tspace.\tCounseling\tshould\tfocus\ton\tthe\tconsumption\tof
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very\thigh\tnutrient\tfoods.\tShe\tmust\teat\tvery\tfrequently,\tpossibly\tevery\thour,\tand\tmust\tfocus\ton\tfoods\nthat\taid\tfetal\tgrowth\teach\ttime\tshe\teats.\tUsing\tfruits\tand\tvegetables\tas\tdesserts\trather\tthan\tsnacks\noften\thelps,\tas\tdoes\tsuggesting\tthat\tshe\teat\tbefore\tdrinking\n\tliquids.\tConsumption\tof\tany\tfoods\tthat
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liquids.\tConsumption\tof\tany\tfoods\tthat\ndon’t\thelp\tfetal\tgrowth\tand\tdevelopment\tshould\tbe\tdiscouraged.
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TABLE\t14.12\nNutrient\tRecommendations\tfor\tWomen\tPregnant\twith\tTwins\nNutrient\nTwins\nComments\nCalories\nUnderweight:\t4000\tkcal\nNormal:\t3000-3500\tkcal\nOverweight:\t3250\tkcal\nObese:\t2700-3000\tkcal\nEstimated\tneeds\tare\t40-45\tkcal/kg.\tMonitor\tweight\tgain\tand\nmodify\tcalories\tto\tmeet\ttarget\n\tweight\tgoals.\nProtein\nUnderweight:\t200\tg\nNormal:\t175\tg
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-0.0726654902100563, -0.06384239345788956, -0.019711993634700775, 0.0694989562034607, 0.06716141104698181, -0.015056092292070389, -0.14348800480365753, 0.07860183715820312, 0.04497382789850235, -0.037911199033260345, 0.01667633280158043, -0.009274443611502647, -0.05379463732242584, -0.02489384077489376, -0.09108536690473557, 0.0713287740945816, 0.009734610095620155, -0.00012414979573804885, -0.008492140099406242, -0.02594943717122078, 0.04464145749807358, -0.026663832366466522, 0.025969764217734337, -0.010171793401241302 ]
weight\tgoals.\nProtein\nUnderweight:\t200\tg\nNormal:\t175\tg\nOverweight:\t163\tg\nObese:\t150\tg\nTarget\t20%\tof\tcalories\tfrom\tprotein.\tChoose\tconcentrated\nsources\tas\tspace\tbecomes\tlimiting.\nCarbohydrate\nUnderweight:\t400\tg\nNormal:\t350\tg\nOverweight:\t325\tg\nObese:\t300\tg\nEncourage\tlow\tglycemic\tchoices.\nFat\nUnderweight:\t178\tg\nNormal:\t156\tg\nOverweight:\t144\tg
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Fat\nUnderweight:\t178\tg\nNormal:\t156\tg\nOverweight:\t144\tg\nObese:\t133\tg\nEncourage\thealthy\tfats.\nVitamin\tD\n1000\tIU/day\tor\tmore\tas\nneeded\t(1000\tIU/day\nraises\tblood\t5\nmg/dL)\nAssessment\tof\tmaternal\tlevels\tshould\tbe\tconsidered\tin\tfirst\nand\tearly\tthird\ttrimesters\tto\tallow\talterations\tin\tthe\nsupplemental\tdose,\tespecially\timportant\tif\tthe\tmother\tis\ton
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supplemental\tdose,\tespecially\timportant\tif\tthe\tmother\tis\ton\nbed\trest.\nVitamin\tC\n500-1000\tmg/day\nThis\tis\thalf\tof\tthe\tUL\tof\t1800-2000\tmg/day.\tSee\tmore\trecent\ncautions.\nVitamin\tE\n400\tmg/day\nThis\tis\thalf\n\tof\tthe\tUL\tof\t800-1000\tmg/day.\tSee\tmore\trecent\ncautions.\nZinc\n15\tmg/day\t(T1);\t30-45\nmg/day\t(T2-3)
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cautions.\nZinc\n15\tmg/day\t(T1);\t30-45\nmg/day\t(T2-3)\nDiet\talone\tmay\tnot\tbe\tenough.\tSupplementation\tmay\tbe\nrequired.\nIron\n30\tmg/day\tas\tpart\tof\t1\nmultivitamin/day\n(T1),\t2\nmultivitamins/day\n(T2\tand\tT3)\nTwin\tgestation\trequirement\tis\tlikely\tdouble\tthat\tof\tsingletons.\nHigher\tintakes\tmay\tbe\tneeded\tfor\ttreatment\tof\tanemia.\nFolic\tacid\n800-1000\tmcg/day,\n\t4
[ -0.033304017037153244, 0.00237265694886446, 0.019689638167619705, 0.003336928552016616, -0.03489093855023384, -0.03128111734986305, 0.07729045301675797, 0.08453385531902313, -0.0643751323223114, -0.005442237947136164, 0.07686133682727814, -0.07260720431804657, -0.009357722476124763, 0.009443944320082664, -0.103604257106781, -0.03721480444073677, -0.020768266171216965, -0.0038315155543386936, -0.0585642009973526, -0.008368471637368202, -0.02364775538444519, 0.05425076186656952, 0.03885924071073532, 0.03442094847559929, 0.0004793998086825013, 0.02079290710389614, -0.046839043498039246, 0.04056717827916145, -0.015495729632675648, -0.04732077568769455, -0.11512976884841919, 0.058208003640174866, 0.009142052382230759, -0.0475122444331646, 0.0415576733648777, 0.008233158849179745, -0.05029338598251343, -0.020449085161089897, 0.002501722425222397, 0.027639660984277725, 0.007504951674491167, -0.08492174744606018, -0.02980545163154602, 0.026088299229741096, 0.03131011873483658, -0.03182824328541756, -0.06511697173118591, -0.0053122141398489475, 0.01603354886174202, 0.08835174888372421, -0.035773370414972305, -0.014375351369380951, -0.07426024228334427, 0.04688794165849686, -0.006717120762914419, -0.0026956130750477314, -0.09917475283145905, -0.07267045974731445, -0.01918916404247284, -0.006105420179665089, -0.03984377160668373, 0.009940656833350658, -0.0691755935549736, 0.015840981155633926, 0.006068228278309107, 0.02928289771080017, -0.02295922115445137, -0.007954459637403488, 0.05076358839869499, 0.056621700525283813, -0.02616800367832184, -0.0020221183076500893, -0.06066838279366493, 0.12790518999099731, -0.07477468997240067, 0.03944117948412895, 0.06211728975176811, -0.03822759538888931, 0.0013683136785402894, -0.05716912820935249, -0.09093543142080307, 0.09294532984495163, 0.10651276260614395, 0.03714023157954216, 0.03438582271337509, 0.04678823798894882, -0.020597418770194054, 0.15556807816028595, 0.05804194137454033, -0.0004824378702323884, 0.11666412651538849, 0.038308773189783096, -0.049602847546339035, 0.010988005436956882, -0.04753541573882103, -0.021314550191164017, -0.04294239357113838, -0.007693690713495016, -0.06004270911216736, 0.021570030599832535, -0.01142010185867548, -0.010412129573523998, -0.04289308190345764, 0.037093598395586014, -0.050318360328674316, -0.013441111892461777, -0.013071577064692974, -0.048502758145332336, -0.00197207136079669, 0.0010102210799232125, 0.002982460893690586, 0.07406198233366013, 0.0904807597398758, -0.07766488939523697, -0.026233354583382607, 0.0014989610062912107, -0.04739018529653549, -0.001910713966935873, 0.14388316869735718, 0.08035671710968018, 0.017983246594667435, -0.0066208383068442345, 0.02774888463318348, 0.003418013686314225, -0.00727238692343235, 0.002328442642465234, 0.05530664324760437, 3.632960432790299e-33, 0.07581478357315063, 0.043011389672756195, 0.03034329041838646, 0.06309240311384201, -0.023947924375534058, 0.0084754079580307, -0.07075387984514236, -0.08326203376054764, -0.03996824845671654, 0.012733208946883678, -0.1037444993853569, -0.05354833975434303, 0.028939543291926384, -0.01765557937324047, -0.03459729254245758, -0.08433054387569427, 0.030394524335861206, 0.05501021444797516, -0.008090554736554623, 0.0058072335086762905, 0.001406271941959858, 0.03773118183016777, 0.02313164621591568, -0.0010921848006546497, -0.04230668023228645, 0.024141211062669754, -0.02024371549487114, 0.03656970337033272, 0.024900812655687332, 0.02717328630387783, 0.04754607751965523, -0.07165976613759995, -0.041799042373895645, -0.07637882232666016, -0.002103364560753107, 0.02259221486747265, -0.0066817509941756725, 0.005311127752065659, 0.04050406441092491, 0.0007238858961500227, -0.010998595505952835, 0.034085340797901154, 0.01436198502779007, 0.07971290498971939, 0.05944164842367172, -0.06280411034822464, 0.0009425787138752639, -0.01417971309274435, 0.019152339547872543, -0.017986085265874863, -0.07193662971258163, -0.011777263134717941, 0.07426716387271881, -0.03319045156240463, -0.10628664493560791, 0.045433592051267624, -0.03464007005095482, 0.02753927931189537, -0.0013689068146049976, 0.07658043503761292, 0.043070536106824875, 0.03826526552438736, -0.008842299692332745, -0.05518224462866783, 0.005108665209263563, 0.015133281238377094, -0.11723530292510986, -0.03135230019688606, -0.00449152709916234, 0.017620133236050606, -0.03687838092446327, -0.017020028084516525, 0.09939758479595184, -0.025823727250099182, 0.06863012909889221, 0.023618483915925026, 0.10290220379829407, -0.005001571960747242, 0.011179600842297077, -0.10906247049570084, -0.039327770471572876, -0.03308344632387161, 0.00425610039383173, 0.0301715899258852, 0.00975644402205944, -0.04606729745864868, 0.0030685667879879475, 0.004435069393366575, -0.07343261688947678, 0.004960673861205578, -0.022432802245020866, 0.0028300266712903976, 0.010951641015708447, -0.0611993782222271, -0.06807926297187805, -4.1993136110164773e-33, -0.012018836103379726, 0.04012751579284668, 0.0004479976778384298, 0.020586948841810226, -0.04143453389406204, -0.004836592823266983, 0.010519629344344139, 0.046208757907152176, 0.05987096577882767, 0.026125090196728706, 0.09378460049629211, 0.0522911474108696, -0.073296457529068, -0.1417568176984787, -0.10336533933877945, 0.012042582966387272, -0.025109751150012016, 0.11057688295841217, -0.05393187329173088, -0.048125188797712326, -0.06596232205629349, 0.07631250470876694, -0.044307854026556015, 0.034887783229351044, 0.03134778141975403, 0.09562891721725464, -0.021215476095676422, -0.02626671828329563, 0.0009273668401874602, 0.012044616974890232, -0.011089365929365158, -0.03701470419764519, -0.01485992968082428, 0.09411686658859253, -0.027201920747756958, 0.0005584231694228947, 0.07824530452489853, -0.058544084429740906, -0.005865259561687708, 0.048533156514167786, 0.029873579740524292, 0.01318392064422369, 0.06407219916582108, -0.021081652492284775, -0.010756195522844791, 0.041906774044036865, -0.017641689628362656, -0.01421151403337717, -0.0206533782184124, 0.04585118591785431, 0.04905202239751816, 0.050158191472291946, -0.06529255211353302, 0.08748605102300644, 0.08371848613023758, -0.02909197472035885, 0.031601984053850174, -0.15060873329639435, -0.09911280125379562, -0.019138937816023827, -0.029829153791069984, 0.008397947065532207, -0.01940523274242878, 0.011428585276007652, 0.059863414615392685, -0.04352789744734764, -0.0682164803147316, -0.0018379533430561423, 0.01868397369980812, -0.01777786575257778, -0.005002850666642189, 0.014573430642485619, -0.03748448193073273, -0.17424950003623962, 0.032371677458286285, -0.08095895498991013, 0.08869052678346634, -0.017095591872930527, -0.014588180929422379, 0.005941916257143021, -0.0736757442355156, -0.057425662875175476, 0.012219063006341457, 0.046678584069013596, -0.024565724655985832, -0.04018111899495125, 0.005956325214356184, 0.0028836119454354048, -0.009610850363969803, 0.09476978331804276, -0.07091809064149857, 0.028596604242920876, 0.03588045388460159, 0.10008557885885239, 0.042841359972953796, -5.4046207509372834e-8, 0.06576820462942123, 0.005385261494666338, -0.030207661911845207, -0.0013599664671346545, 0.04648676514625549, -0.05953732505440712, -0.05093017593026161, 0.009672366082668304, -0.008272679522633553, -0.029229700565338135, 0.10525745153427124, 0.055008985102176666, -0.07107897102832794, -0.12398981302976608, 0.030889436602592468, -0.03429057076573372, -0.01424674317240715, 0.10100313276052475, -0.04794084653258324, -0.07570299506187439, 0.041925664991140366, 0.034653808921575546, 0.00805396307259798, -0.022580713033676147, 0.014672907069325447, 0.04972962662577629, 0.007284943480044603, 0.041614461690187454, 0.016311263665556908, 0.01752631738781929, 0.013292750343680382, -0.058210358023643494, 0.048529401421546936, -0.018319154158234596, -0.01836811751127243, 0.007352802436798811, -0.037111155688762665, 0.04411144182085991, 0.00843203254044056, 0.12409976124763489, -0.054229117929935455, -0.06354376673698425, -0.04313088580965996, 0.08281520009040833, 0.05022177845239639, -0.029290564358234406, -0.06465790420770645, 0.0504564605653286, 0.00017159702838398516, -0.08542095869779587, -0.01045663096010685, 0.047342561185359955, 0.02278033085167408, 0.04176836088299751, -0.0937889814376831, 0.08382253348827362, 0.03510245680809021, -0.02199449948966503, 0.02601161226630211, 0.0020218975841999054, 0.00817628763616085, -0.009800825268030167, -0.0184134840965271, -0.01771254651248455 ]
Folic\tacid\n800-1000\tmcg/day,\n\t4\nmg\tif\twith\ta\thistory\nof\tNTD\nCalcium\n1500\tmg/day\t(T1);\n2500-3000.\tmg\t(T2-\n3)\nUL:\t2500\tmg/day,\tconsider\tlimiting\tif\tthere\tis\ta\thistory\tof\nkidney\tstones.\nMagnesium\n400\tmg/day\t(T1);\t800-\n1200.\tmg/day\t(T2-3)\nDHA\t+\tEPA\n300-1000\tmg/day
[ -0.028905687853693962, 0.007537818048149347, -0.07481066882610321, -0.02652973309159279, -0.08100414276123047, -0.06861402839422226, 0.005894692149013281, 0.13124753534793854, -0.041245974600315094, -0.02364933304488659, 0.08266355097293854, -0.06748180836439133, 0.025500599294900894, 0.019208282232284546, -0.04383218288421631, -0.04730222001671791, -0.019138675183057785, 0.00796482339501381, -0.04351258650422096, -0.005744368769228458, 0.017497403547167778, -0.026329364627599716, -0.009262941777706146, -0.014519063755869865, 0.027913441881537437, 0.04354654997587204, -0.04031352326273918, 0.01811557449400425, -0.02408752590417862, -0.043675728142261505, -0.02900947816669941, 0.07438203692436218, 0.03273235633969307, -0.039019931107759476, 0.016006389632821083, 0.027233771979808807, -0.13508248329162598, -0.01694786176085472, 0.0239911787211895, -0.02803928777575493, 0.015657013282179832, -0.04955156147480011, 0.010708914138376713, -0.014418601989746094, 0.04263840988278389, -0.01665905863046646, -0.03832678869366646, 0.0715641900897026, 0.0035612606443464756, 0.11528896540403366, -0.035414181649684906, -0.02213061787188053, -0.0786362886428833, 0.10572732985019684, 0.009445113129913807, -0.015660595148801804, -0.11632628738880157, -0.04987387731671333, -0.004282986745238304, 0.05263737589120865, -0.047502316534519196, 0.03672698885202408, -0.05457929149270058, -0.02335301972925663, 0.07407944649457932, 0.04735367000102997, -0.03425659239292145, -0.02862090803682804, 0.029743079096078873, 0.05213022977113724, -0.04403989389538765, 0.020934714004397392, -0.002249567536637187, 0.06536512821912766, -0.019813871011137962, 0.030689941719174385, 0.03090238943696022, -0.028303267434239388, 0.004880939144641161, -0.03394164517521858, 0.0013863800559192896, 0.03533969074487686, 0.05609768629074097, 0.051031675189733505, 0.03333747014403343, 0.024023307487368584, 0.03631944954395294, 0.17826175689697266, 0.04086137190461159, 0.037044450640678406, 0.08803582936525345, 0.1205856055021286, -0.07783976942300797, 0.0014236309798434377, -0.06513537466526031, 0.009262173436582088, -0.04108555242419243, -0.01176865678280592, -0.04024989530444145, 0.019183285534381866, -0.021240970119833946, 0.014468693174421787, -0.024080904200673103, 0.0306077990680933, -0.055837247520685196, -0.008367401547729969, 0.033864643424749374, 0.03512145206332207, -0.053220003843307495, 0.006050314754247665, -0.011426547542214394, 0.07468531280755997, 0.038984932005405426, -0.02911742776632309, 0.026142869144678116, 0.020794175565242767, 0.009696406312286854, 0.01228254847228527, 0.08077822625637054, 0.04375389963388443, 0.06599456816911697, -0.005951274652034044, 0.028795462101697922, 0.007747971452772617, -0.05312346667051315, 0.010055266320705414, 0.027732403948903084, 3.33756200850652e-33, -0.015406518243253231, 0.03385086730122566, 0.042181190103292465, 0.07581819593906403, -0.03833349421620369, 0.029729079455137253, -0.026793966069817543, 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0.04078345000743866, 0.01675506681203842, 0.12187285721302032, 0.08592895418405533, -4.341375614558274e-8, 0.071225605905056, -0.09924543648958206, -0.022993015125393867, -0.01063829567283392, 0.04064946994185448, -0.030814364552497864, -0.02851409837603569, -0.02049681730568409, 0.06522885710000992, -0.05464822053909302, 0.07713878899812698, 0.0724056139588356, -0.02629975974559784, -0.04915047436952591, -0.020147275179624557, -0.025568418204784393, -0.03830615058541298, 0.012657618150115013, -0.04204978421330452, -0.08434496074914932, -0.006035547703504562, 0.024062564596533775, -0.05266685038805008, -0.04343847557902336, 0.046526189893484116, 0.01431953813880682, -0.02239106222987175, -0.0049903010949492455, -0.0012302115792408586, 0.027240479364991188, 0.07561687380075455, -0.03913705423474312, 0.0553288608789444, -0.03638215363025665, -0.06884302943944931, 0.008165019564330578, -0.06410206109285355, 0.05905940756201744, -0.0640154555439949, 0.10798653960227966, -0.05583244934678078, -0.09500104188919067, -0.01955176331102848, 0.059214696288108826, 0.031342677772045135, -0.02864036150276661, -0.07984154671430588, 0.005966160446405411, -0.015170403756201267, -0.03790707886219025, 0.008859643712639809, 0.07389605790376663, -0.008895320817828178, -0.005748147610574961, -0.07624156028032303, 0.0667017251253128, 0.021273883059620857, -0.035136036574840546, 0.011785277165472507, -0.039876826107501984, -0.04686028137803078, 0.012207272462546825, -0.014627478085458279, -0.041395362466573715 ]
400\tmg/day\t(T1);\t800-\n1200.\tmg/day\t(T2-3)\nDHA\t+\tEPA\n300-1000\tmg/day\nAdapted\tfrom\tGoodnight\tW,\tNewman\tR:\tOptimal\tnutrition\tfor\timproved\ttwin\tpregnancy\toutcome,\t\nObstet\tGynecol\n\t114:1121,\t2009;\tLuke\tB:\tNutrition\nfor\tmultiples,\n\t\nClin\tObstet\tGynecol\n\t58:585,\t2015;\tLuke\tB,\tEberlein\tT,\tNewman\tR:\t\nWhen\tyou’re\texpecting\ttwins,\ttriplets,\tor\tquads
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0.005845552776008844, 0.09022975713014603, -0.014237653464078903, 0.10350725054740906, 0.048756711184978485, -5.380534062737752e-8, 0.0032758894376456738, -0.02871866524219513, -0.03377677872776985, 0.0077702985145151615, 0.033860065042972565, -0.04813087359070778, 0.020418625324964523, 0.002706569153815508, -0.0030654296278953552, -0.01784534379839897, 0.09206479787826538, 0.027003305032849312, -0.014920222572982311, -0.06786276400089264, 0.040694013237953186, -0.01512045320123434, -0.0644073411822319, 0.06829614192247391, -0.03213530778884888, -0.10848899185657501, 0.029255609959363937, 0.03443694859743118, 0.00952429510653019, -0.02005588263273239, -0.00536877429112792, 0.07002650946378708, -0.01026579737663269, 0.05025787651538849, 0.03136493265628815, -0.008336201310157776, 0.07329072803258896, -0.021789129823446274, 0.012269681319594383, -0.025818774476647377, -0.05501725897192955, 0.00461200624704361, -0.04907169193029404, 0.03242001309990883, -0.07182840257883072, 0.12504149973392487, -0.04000921547412872, -0.05264334753155708, 0.012737621553242207, 0.07839391380548477, 0.01714390516281128, -0.02963170036673546, -0.042644813656806946, 0.05626782774925232, 0.01153244636952877, -0.05326039344072342, 0.004313973244279623, 0.04189670830965042, 0.009405435062944889, -0.022002844139933586, -0.04812568053603172, 0.044919028878211975, 0.006607310846447945, -0.018230820074677467, -0.0006505544297397137, 0.03497445583343506, -0.015782693400979042, 0.015126805752515793, -0.0154997194185853, -0.04440543055534363 ]
When\tyou’re\texpecting\ttwins,\ttriplets,\tor\tquads\n,\ted\t4,\tNew\tYork,\n2017,\tHarper.\t\nDHA\n,\tDocosahexaenoic\tacid;\t\nEPA\n,\teicosapentaenoic\tacid;\t\nNTD\n,\tneural\ttube\tdefect;\t\nT\n,\ttrimester;\t\nUL\n,\ttolerable\tupper\tlimit.\nAdolescent\tpregnancy\nPublic\thealth\tinitiatives\thave\thelped\treduce\tthe\tincidence\tof\tteen\tpregnancies\toverall,\tbut\tit\ncontinues
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continues\n\tas\ta\tmajor\tproblem\tin\tthe\tUnited\tStates\tamong\tsome\tminority\tgroups\t(\nCDC,\t2018c\n).\tRisk\nfactors\tfor\tpoor\toutcome\tin\tpregnant\tadolescents\tare\tlisted\tin\t\nBox\t14.3\n.\nBOX\t14.3\nRisk\tFactors\tfor\tPoor\tPregnancy\tOutcome\tin\tTeenagers\n•\t\nYoung\tmaternal\tage\n•\t\nPregnancy\tless\tthan\t2\tyears\tafter\tonset\tof\tmenarche\n•
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•\t\nPregnancy\tless\tthan\t2\tyears\tafter\tonset\tof\tmenarche\n•\t\nPoor\tnutrition\tand\tlow\tprepregnancy\tweight\n•\t\nPreexisting\tanemia\n•\t\nInappropriate\tweight\n\tgain\t(too\tlow\tand\ttoo\thigh)\n•\t\nObesity\n•\t\nSexually\ttransmitted\tdisease\tor\tinfection\n•\t\nSubstance\tabuse:\tsmoking,\tdrinking,\tand\tdrugs\n•\t\nPoverty\n•\t\nLack\tof\tsocial\tsupport\n•\t\nLow\teducational\tlevel
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•\t\nRapid\trepeat\tpregnancies\n•\t\nLack\tof\taccess\tto\tage-appropriate\tprenatal\tcare\n•\t\nLate\tentry\tinto\tthe\thealth\tsystem\n•\t\nUnmarried\tstatus\n•\t\nUnstable\thousing,\tshelter\tliving,\thomelessness
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0.11394000053405762, 0.06518649309873581, 0.010335066355764866, -0.005858486983925104, 0.05616190284490585, 0.024370938539505005, -0.04500507190823555, -0.0065486677922308445, 0.08313886821269989, -0.03744511306285858, -0.034412700682878494, -0.0007798721781000495, 0.094898521900177, -0.018904253840446472, -0.040656983852386475, -0.005373281892389059, 0.0711524710059166, 0.1324695646762848, 0.05096357315778732, -0.02048993669450283, -0.019990893080830574, 0.11945181339979172, 0.05058939754962921, 0.07423648238182068, -0.0037002030294388533 ]
Increased\trates\tof\tLBW\tand\tpreterm\tdelivery\tare\tespecially\tcommon\tamong\tthose\twho\tare\tvery\nyoung\tand\tunderweight,\tfor\twhom\tthere\tmay\tbe\tcompetition\tfor\tnutrients\tbetween\tthe\tmother\tand\nthe\tfetus\t(see\t\nChapter\t17\n).\tPoor\toutcomes\tare\talso\tcommon\tin\tobese\tteens\tthat\tbecome\tpregnant.
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-0.0014819682110100985, 0.02676718682050705, 0.001471160096116364, 0.06404232978820801, 0.07695884257555008, -0.07662177085876465, -0.03877871856093407, 0.06892217695713043, -0.004272126592695713, -0.07209909707307816, 0.010601239278912544, 0.11324077844619751, -0.008848217315971851, -0.03572284057736397, -0.06523419916629791, 0.02192486822605133, 0.0421128012239933, 0.04646369069814682, -0.017949748784303665, 0.04954160749912262, 0.09067141264677048, 0.012320645153522491, 0.055398814380168915, -0.02805398404598236 ]
).\tPoor\toutcomes\tare\talso\tcommon\tin\tobese\tteens\tthat\tbecome\tpregnant.\nMany\tteens\tenter\tpregnancy\twith\tsuboptimal\tnutritional\tstatus,\tespecially\tfor\tiron,\tcalcium,\tand\tfolic\nacid.\tIn\tone\n\tstudy,\twomen\tin\tthe\tUnited\tStates\twho\tgave\tbirth\tas\tteens\twere\tmore\tlikely\tto\tbe\noverweight\tor\tobese\tas\tadults\t(\nChang\tet\tal,\t2013\n).
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0.043223343789577484, 0.014066766016185284, 0.0034519594628363848, 0.08233463019132614, 0.06364084035158157, -0.10004492104053497, -0.003239271929487586, 0.08850555121898651, -0.004384647123515606, -0.028105353936553, -0.024082327261567116, 0.12372569739818573, 0.041310183703899384, -0.06186792254447937, -0.011270171962678432, 0.03211485594511032, 0.06458618491888046, 0.07253618538379669, -0.04675702378153801, 0.053825199604034424, 0.09812031686306, 0.050638485699892044, 0.053364936262369156, -0.022169582545757294 ]
overweight\tor\tobese\tas\tadults\t(\nChang\tet\tal,\t2013\n).\nImproved\tdietary\tpractices\tcan\tbe\tone\tof\tthe\tmost\timportant\tfactors\tfor\tthe\tpregnant\tteen.\tIn\ncounseling\tyoung\tmothers,\tthe\tnutrition\tprofessional\tmust\tbe\taware\tof\tthe\tteen’s\tpsychosocial\tand\nliteracy\tlevels,\ther\teconomic\tstatus\tand\tlevel\tof\tindependence,\tas\twell\n\tas\ther\tcultural\tenvironment,
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-0.05883638188242912, -0.0967521220445633, -0.1040773019194603, -0.03793118894100189, -0.0037056903820484877, 0.08697797358036041, 0.0021935205440968275, -0.023712748661637306, 0.060877468436956406, 0.06348869204521179, -0.045765262097120285, 0.014428941532969475, -0.07863500714302063, -0.09058182686567307, -0.0330745205283165, 0.034490328282117844, 0.01971718668937683, 0.01679597795009613, 0.017207736149430275, 0.07135751843452454, -0.0917201116681099, -0.05191804841160774, -0.0385897159576416, -0.030351417139172554, -0.04577803239226341, -0.024903787299990654, -0.0034622587263584137, -0.08964861184358597, -0.13153918087482452, 0.07661551237106323, -0.018807929009199142, 0.08222055435180664, -0.005299868993461132, -0.04613640904426575, -0.024338768795132637, -0.03463706001639366, -0.0799180418252945, 0.06757501512765884, -0.0036294846795499325, -0.020380904898047447, 0.05274675041437149, -0.007228383794426918, 0.030913179740309715, 0.05108485743403435, 0.09019717574119568, -0.021270757541060448, 0.053667787462472916, -0.01119797769933939, 0.023036658763885498, 0.03328154608607292, -5.56112205174486e-8, 0.0017177475383505225, -0.012553917244076729, 0.04584302380681038, 0.013804299756884575, 0.012712232768535614, -0.018900373950600624, 0.08209946006536484, 0.005364608485251665, -0.028297072276473045, 0.02096465602517128, 0.020495202392339706, 0.07645601034164429, -0.00821615755558014, -0.05284067615866661, 0.07202785462141037, -0.01667783036828041, -0.03137165680527687, 0.12788698077201843, -0.044510796666145325, -0.09745915234088898, 0.01724795065820217, 0.08355610817670822, -0.03403029963374138, -0.005866801366209984, -0.017408447340130806, 0.011000222526490688, -0.07702428102493286, -0.0169024970382452, 0.006323202047497034, 0.06849140673875809, 0.05393550917506218, -0.03000236675143242, -0.04003923013806343, -0.08698039501905441, -0.01574745401740074, 0.042548686265945435, -0.011734697967767715, -0.03797336295247078, 0.023167259991168976, 0.149016335606575, -0.018692079931497574, 0.011704893782734871, 0.021054407581686974, 0.09797854721546173, 0.11654236167669296, -0.05989064648747444, -0.05355919897556305, 0.12324143201112747, 0.006226466502994299, -0.08746614307165146, -0.021194132044911385, 0.045725442469120026, -0.008791211992502213, -0.011105651967227459, -0.08034026622772217, 0.037329357117414474, 0.06277259439229965, 0.05816715955734253, -0.0677335187792778, 0.010419000871479511, 0.10638074576854706, 0.06095298379659653, 0.04372124746441841, -0.018457122147083282 ]
as\ther\tcultural\tenvironment,\nall\tof\twhich\tmay\tinfluence\ther\tfood\tchoices.\nComplications\tand\tnutritional\timplications\nMany\tof\tthe\tfollowing\tcomplications\tfollow\tfrom\tthe\tnormal\thormonal\tchanges\tduring\tpregnancy.\nThese\tchanges\tcause\tthe\tGI\ttransit\tto\tslow\tso\tthat\tmore\tnutrients\tare\tavailable\tto\tthe\tfetus.
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-0.012166663073003292, -0.004139440134167671, -0.037895701825618744, -0.003156152321025729, -0.01033389288932085, -0.06809835135936737, -0.03047339804470539, -0.1008465364575386, 0.06971549242734909, 0.025592274963855743, -0.013668916188180447, -0.025817373767495155, -0.08030203729867935, -0.05368549004197121, -0.04592939838767052, -0.029061514884233475, 0.015631603077054024, -0.05042306333780289, 0.06736662238836288, 0.01006393600255251, 0.02670666202902794, -0.008244538679718971, 0.04994494095444679, -0.014410777948796749, 0.08323630690574646, -0.057176508009433746, 0.041153669357299805, -0.00268305535428226, 0.11566692590713501, -0.05198908969759941, 0.033185143023729324, 0.07343332469463348, -0.043616946786642075, -0.005562543869018555, -0.08656079322099686, -0.10117318481206894, 0.061024848371744156, 0.006780911702662706, -0.03333289921283722, -0.027638694271445274, 0.031843967735767365, -0.0061079333536326885, 0.0033483020961284637, 0.0009116961155086756, -0.0158892460167408, -0.030136724933981895, -0.06760846078395844, 0.06173938140273094, -0.04949220269918442, -0.05064212903380394, -0.011514171026647091, -0.01731228642165661, -0.057264912873506546, 0.03230579197406769, -0.009014689363539219, -0.017365602776408195, -0.015047432854771614, 0.060424212366342545, 0.04594216123223305, -0.06829672306776047, -0.07919621467590332, -0.06972332298755646, -0.12056852877140045, 0.028914425522089005, -0.04451269283890724, -0.06139819696545601, -0.006801345851272345, 0.05387503281235695, -0.0843268558382988, 0.01810811087489128, -0.014520404860377312, -0.04684628173708916, -0.016505921259522438, 0.16606086492538452, 0.05112460255622864, 0.002370630158111453, -0.028920505195856094, 0.005853072740137577, 0.05571773275732994, -0.08827833086252213, -0.08560898900032043, 0.00759113859385252, 3.802631287387988e-33, 0.05406562611460686, 0.052772365510463715, 0.026978814974427223, 0.03482000157237053, 0.06649766862392426, 0.0357961431145668, -0.028747057542204857, -0.029195083305239677, -0.04813416302204132, 0.042031895369291306, -0.06073073670268059, 0.00032952663605101407, -0.042222194373607635, 0.055355869233608246, -0.011870766058564186, -0.044761013239622116, -0.08562546223402023, 0.06810612231492996, -0.04233057051897049, 0.008528460748493671, -0.03643201291561127, 0.14374610781669617, 0.027124816551804543, -0.0030874419026076794, -0.07734370231628418, -0.05962211638689041, 0.024335026741027832, 0.005308344028890133, -0.03668035939335823, 0.03301046043634415, 0.028808092698454857, -0.016174083575606346, -0.0004048912087455392, -0.026518074795603752, -0.04119669273495674, -0.028005259111523628, -0.046541955322027206, 0.007690996862947941, 0.029351120814681053, 0.0018333852058276534, -0.07981975376605988, -0.0019226677250117064, -0.002924258355051279, 0.05749593302607536, 0.030056023970246315, 0.021271388977766037, 0.031640972942113876, -0.027458446100354195, 0.007239439524710178, -0.026903560385107994, 0.01588115468621254, -0.03667433187365532, 0.06736953556537628, -0.007096742745488882, -0.01556230615824461, -0.000923326937481761, -0.0023967225570231676, 0.058039888739585876, -0.07007217407226562, 0.08649828284978867, 0.033210840076208115, 0.024946752935647964, 0.03791347146034241, -0.06695405393838882, 0.06474783271551132, -0.00039212036062963307, -0.11741145700216293, -0.047546617686748505, 0.048355188220739365, 0.011678928509354591, -0.05726896598935127, 0.03163975849747658, -0.006040743086487055, 0.05036257952451706, 0.09380418807268143, -0.0002455077483318746, 0.013642655685544014, -0.10455845296382904, 0.018761679530143738, -0.0638715922832489, -0.07901904731988907, -0.008748804219067097, -0.014720762148499489, -0.013687375001609325, 0.0011880389647558331, -0.04470135271549225, 0.05292767286300659, -0.035960063338279724, 0.015010030008852482, -0.01031041145324707, -0.01553081814199686, 0.06481471657752991, 0.05436078831553459, -0.0900048315525055, -0.07264295965433121, -4.489317618255936e-33, -0.052872296422719955, -0.014084731228649616, -0.07001303136348724, 0.037738364189863205, -0.03938741981983185, -0.015113218687474728, -0.00570890586823225, 0.07023207098245621, 0.03368354216217995, -0.041356708854436874, 0.058505140244960785, 0.013799325563013554, -0.00854724831879139, -0.0966496467590332, -0.04043680429458618, -0.0010086249094456434, 0.02100202441215515, 0.08560334891080856, -0.022157464176416397, 0.008535460568964481, -0.05606282129883766, -0.030079636722803116, -0.13076572120189667, 0.04423908516764641, 0.026211941614747047, 0.0438726469874382, 0.02458925172686577, -0.040438272058963776, 0.070445716381073, 0.028369639068841934, 0.04615233466029167, -0.010695641860365868, -0.051510777324438095, 0.04881558567285538, 0.010961627587676048, -0.0025545659009367228, 0.011906278319656849, -0.029144586995244026, -0.06785286962985992, 0.007139839231967926, 0.03791509568691254, -0.00416957912966609, 0.08766478300094604, -0.022869285196065903, 0.01488257385790348, -0.009331442415714264, -0.052883636206388474, -0.07423461228609085, -0.011909605003893375, 0.023226529359817505, 0.1011558547616005, -0.021618876606225967, -0.06878796964883804, 0.001813194015994668, 0.03912150114774704, 0.023724429309368134, 0.0453653559088707, -0.09928593039512634, -0.04033263027667999, -0.04595491290092468, -0.010179235599935055, 0.003146285191178322, 0.03392837569117546, -0.01288048829883337, 0.03270610794425011, -0.07455066591501236, -0.059208743274211884, 0.004680403973907232, -0.02743195928633213, -0.04475461691617966, -0.007171890698373318, -0.02063438668847084, -0.11753862351179123, -0.16714295744895935, 0.04467673599720001, -0.020856091752648354, 0.05516698956489563, -0.04568932577967644, -0.025510065257549286, -0.01548714004456997, -0.04789749160408974, -0.027051199227571487, 0.01621059700846672, -0.018777716904878616, -0.0251372791826725, -0.06166061758995056, -0.0396619513630867, 0.017913414165377617, 0.0716719925403595, 0.06761112809181213, 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0.08353035151958466, -0.01859576627612114, 0.011296231299638748, 0.10978364944458008, 0.07229135930538177, -0.04458160325884819, -0.03511463478207588, 0.08510433882474899, -0.009080545045435429, -0.09344843775033951, -0.029342103749513626, 0.09814703464508057, 0.00889594852924347, -0.05816689878702164, -0.033160265535116196, 0.027662599459290504, 0.09868013858795166, 0.0416187085211277, 0.005277920980006456, 0.013730506412684917, 0.06627708673477173, 0.07485536485910416, 0.1034669429063797, -0.028965994715690613 ]
However,\tthat\tcauses\tmore\tnausea\tand\tvomiting,\tconstipation,\tand\theartburn.\tAlthough\tnormal,\nthese\tcomplications\tcan\tbe\tuncomfortable\tand\tpotentially\tdangerous\tbut\tcan\tbe\tmanaged.\nConstipation,\themorrhoids,\tand\tdiarrhea\nWith\tthe\thormonal\tchanges\tof\tpregnancy,\twomen\tbecome\tconstipated\tif\tthey\tfail\tto\tconsume
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adequate\twater\tand\tfiber.\tWomen\twho\treceive\tiron\tsupplements\toften\tcomplain\tof\tconstipation.\nThose\twho\tare\ttreated\twith\tondansetron\tfor\tnausea\tand\tvomiting\toften\texperience\tsevere\nconstipation.\tCompression\tof\tthe\tpelvic\tfloor\tby\tthe\tfetus,\tas\twell\tas\tstraining\tduring\tstooling
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-0.02763976715505123, 0.05632742494344711, -0.011425352655351162, 0.07243256270885468, 0.1272727996110916, -0.05106940492987633, -0.056574128568172455, 0.06663567572832108, -0.024169541895389557, -0.09418546408414841, -0.004591588396579027, 0.08003092557191849, 0.027852939441800117, -0.0309341698884964, 0.0029156291857361794, 0.05855106562376022, 0.05015833303332329, 0.03501336649060249, -0.052131928503513336, -0.014344780705869198, 0.03385000303387642, 0.10392916202545166, 0.06342115998268127, -0.018686560913920403 ]
(Valsalva),\tincreases\tthe\trisk\tfor\themorrhoids.\tIncreased\tconsumption\tof\tfluids\tand\tfiber-rich\tfoods\n(see\t\nAppendix\t27\n),\tincluding\tdried\tfruits\t(especially\tprunes),\tusually\tcontrols\tthese\tproblems.\tSome\nwomen\talso\tmay\trequire\ta\tbulking\ttype\tof\tstool\tsoftener\tbut\tlaxatives\tcontaining\tstimulants\tare\tnot
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recommended.\tAdding\tunprocessed\twheat\tbran\tto\tfoods\tis\tsafe\tand\teffective.\nDiarrhea\tmay\talso\tbe\tcaused\tby\ta\tchange\tin\thormones\tearly\tin\tpregnancy.\tIt\tmay\talso\toccur\twhen\na\tmother\tis\tstarting\tlabor.\tInfectious\tand\tother\tmedical\tcauses\tshould\tbe\truled\tout.\tSee\t\nChapter\t27\nfor\ttreatment\toptions.\tPrevention\tof\tdehydration\tis\timportant.
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for\ttreatment\toptions.\tPrevention\tof\tdehydration\tis\timportant.\nCravings,\taversions,\tand\tpica\nMost\twomen\tchange\ttheir\tdiets\n\tduring\ttheir\tpregnancies\tas\ta\tresult\tof\tmedical\tadvice,\tcultural\nbeliefs,\tor\tchanges\tin\tfood\tpreference\tand\tappetite.\tFood\tintake\tin\tpregnancy\tmay\tbe\taffected,\tboth
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positively\tand\tnegatively,\tby\tchanges\tin\thormone\tlevels.\tThere\tis\tlimited\tresearch\ton\tpregnancy’s\neffect\ton\tthe\tvarious\thormones\trelated\tto\tappetite\tcontrol.\tTaste\tpreferences\toften\tchange\tduring\npregnancy,\tlikely\tdue\tto\tthe\tpregnancy\n\thormones\taffecting\tboth\tthe\ttaste\tbuds\tand\tthe\tcentral\nnervous\tsystem\t(\nFaas\tet\tal,\t2010
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nervous\tsystem\t(\nFaas\tet\tal,\t2010\n).\tFood\tavoidances\tmay\tnot\treflect\ta\tmother’s\tconscious\tchoice\tbut\nmay\tinclude\tan\tadverse\tresponse\tto\tsmell\tcaused\tby\tan\tenhanced\tperception\tof\taromas,\ta\nheightened\tgag\tresponse,\tgetting\till\twhile\teating\tor\tsmelling\ta\tparticular\tfood,\tor\taltered\tgastric\ncomfort.\nCravings\tand\taversions.\nCravings\tand\taversions
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0.030332515016198158, -0.012388616800308228, 0.047024935483932495, 0.08890271931886673, -4.727106883706256e-8, -0.01192772388458252, -0.023140350356698036, 0.0092784957960248, -0.015491808764636517, 0.07395212352275848, -0.02432989701628685, 0.021336009725928307, 0.013150704093277454, -0.051603417843580246, -0.06565113365650177, 0.0146305151283741, 0.06851532310247421, -0.056792281568050385, -0.029007960110902786, 0.020021872594952583, 0.02180112712085247, 0.04945768415927887, 0.1628642976284027, -0.007691807579249144, -0.08361241221427917, 0.0018986364593729377, 0.0606938935816288, 0.00039671489503234625, 0.02109287679195404, -0.027725273743271828, -0.002534438855946064, -0.0470568984746933, 0.032851140946149826, -0.006677230354398489, 0.03509350121021271, 0.05567393824458122, -0.07373426109552383, -0.009332711808383465, -0.046546269208192825, -0.02169807255268097, 0.054514046758413315, -0.06042470410466194, -0.047007862478494644, 0.04686184227466583, 0.09708335250616074, -0.022977011278271675, 0.004924366250634193, 0.011065083555877209, 0.08866136521100998, 0.030964141711592674, -0.08603523671627045, 0.020650016143918037, 0.010627335868775845, 0.022822892293334007, -0.07444817572832108, -0.016996856778860092, 0.09278711676597595, -0.011110398918390274, 0.020490732043981552, -0.04386166110634804, 0.039306845515966415, 0.08383049070835114, 0.04431747645139694, -0.039211858063936234, 0.003469314659014344, 0.08042307943105698, 0.09215965867042542, 0.007780557032674551, 0.011187147349119186 ]
comfort.\nCravings\tand\taversions.\nCravings\tand\taversions\n\tare\tpowerful\turges\ttoward\tor\taway\tfrom\tfoods,\tincluding\tfoods\tabout\twhich\nwomen\texperience\tno\tunusual\tattitudes\twhen\tnot\tpregnant.\tIn\tthe\tUnited\tStates\tthe\tmost\tcommonly\ncraved\tfoods\tare\tsweets,\tfruits,\tand\tdairy\tproducts,\tor\tfoods\tthat\tcan\tbe\teaten\tquickly.\tThe\tmost
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0.034705232828855515, -0.012608988210558891, 0.0708804801106453, 0.06780418008565903, -4.116971297207783e-8, -0.00938565842807293, -0.0473189577460289, 0.006560633424669504, 0.05141371861100197, 0.042086631059646606, -0.02025773748755455, 0.09021467715501785, 0.020718848332762718, -0.03565017506480217, 0.0022694366052746773, 0.013730162754654884, 0.12095029652118683, -0.0594107024371624, -0.013998277485370636, 0.06122800335288048, 0.028416434302926064, 0.026021024212241173, 0.09964218735694885, -0.010812432505190372, -0.04768132045865059, 0.032053157687187195, 0.09280374646186829, -0.025953641161322594, 0.029908137395977974, -0.0007761148735880852, 0.005581600591540337, -0.0344930998980999, -0.014947677031159401, 0.07706974446773529, 0.08516702055931091, 0.07637687027454376, -0.04522576183080673, -0.03806887939572334, -0.040088213980197906, -0.042394086718559265, 0.02893850952386856, -0.08647126704454422, -0.005429019685834646, 0.033138521015644073, 0.11118636280298233, -0.03287719190120697, -0.027720332145690918, -0.03263300284743309, 0.08250244706869125, 0.006682646926492453, -0.07104343175888062, -0.05844275280833244, 0.08927050232887268, -0.02145414426922798, -0.02469697967171669, -0.0023773727007210255, 0.07361595332622528, 0.030111566185951233, -0.002598599763587117, -0.016949092969298363, -0.015208532102406025, 0.06074615940451622, -0.007013735361397266, 0.011282905004918575, 0.021475207060575485, 0.03683488443493843, 0.034953199326992035, 0.025260282680392265, -0.018148133531212807 ]
common\taversions\treported\tare\tto\talcohol,\tcoffee,\tmeats,\tand\tthe\tsmell\tof\tfrying.\tHowever,\tcravings\nand\taversions\tare\tnot\tlimited\n\tto\tany\tparticular\tfood\tor\tfood\tgroups,\tthey\toften\toverlap,\tand\tcultural\ndifferences\texist.\tFor\texamples,\tsee\t\nTable\t14.13\n.
[ 0.0180965568870306, -0.0585901215672493, 0.01737412065267563, -0.05728613957762718, -0.01715271733701229, 0.000173704102053307, 0.08649379014968872, 0.003663766197860241, -0.028443751856684685, -0.008773493580520153, 0.09707849472761154, 0.0002900430408772081, -0.0003893418179359287, 0.019541045650839806, -0.018973881378769875, -0.007811786141246557, -0.0402531623840332, 0.04577958583831787, -0.01652447320520878, -0.04185279831290245, -0.0047725895419716835, 0.06408872455358505, 0.023068124428391457, 0.025204893201589584, 0.0108136972412467, 0.0431729331612587, -0.0646112933754921, -0.039223141968250275, 0.06493346393108368, -0.0656014233827591, -0.1272546350955963, 0.08045808970928192, 0.01191855687648058, 0.011606987565755844, 0.07492364943027496, 0.034044794738292694, 0.010324518196284771, -0.01226172223687172, 0.016703560948371887, 0.010148817673325539, -0.016062846407294273, -0.050966810435056686, -0.054931242018938065, 0.04178013280034065, 0.0030621164478361607, -0.044192563742399216, -0.02748417668044567, 0.0025414281990379095, -0.05623060092329979, -0.027653194963932037, -0.06745848059654236, -0.022768519818782806, -0.10330984741449356, 0.05927775055170059, 0.051419783383607864, -0.023169701918959618, -0.03089427947998047, -0.018272485584020615, -0.016122236847877502, 0.01390262134373188, -0.03825928270816803, -0.021694453433156013, -0.08497528731822968, 0.045586634427309036, 0.002434649271890521, 0.05586831644177437, -0.021921681240200996, 0.015336190350353718, -0.002640547463670373, 0.014287418685853481, -0.11947037279605865, -0.009771503508090973, -0.0588085763156414, 0.15075382590293884, -0.04732198640704155, 0.07074105739593506, 0.06844918429851532, 0.007831725291907787, -0.031762439757585526, -0.06555866450071335, -0.1032334715127945, 0.04923505708575249, 0.034541863948106766, 0.03578289598226547, 0.0014000697992742062, 0.0026402920484542847, -0.03567963466048241, 0.0459379218518734, 0.036428458988666534, 0.01649291068315506, -0.04996175318956375, -0.022280344739556313, 0.039072830229997635, -0.025006482377648354, -0.0587589293718338, 0.018912194296717644, 0.06852027773857117, -0.007329093758016825, 0.005892093293368816, 0.03400975465774536, 0.012673902325332165, 0.003199489088729024, 0.060622747987508774, 0.0007596401846967638, -0.06117662042379379, -0.030780911445617676, 0.009488271549344063, -0.09876896440982819, 0.057202231138944626, -0.051219385117292404, -0.06949958205223083, -0.02339867688715458, -0.02266620472073555, -0.11985503137111664, -0.061870358884334564, -0.0929684266448021, -0.08844160288572311, -0.006434459704905748, 0.1363409161567688, 0.04963293671607971, -0.015810303390026093, -0.049527112394571304, 0.04625173658132553, 0.0770379900932312, -0.05661499872803688, -0.04421892389655113, 0.011010425165295601, 1.820706302257348e-33, 0.013286812230944633, 0.06020651012659073, -0.004707003477960825, 0.06776473671197891, 0.03960960730910301, 0.0005406133714132011, -0.03648965805768967, -0.0020033661276102066, -0.08261150121688843, 0.048767853528261185, -0.05312487110495567, 0.021016672253608704, -0.07628297805786133, 0.09679888188838959, 0.07836870849132538, -0.06506761908531189, 0.009390009567141533, 0.04065990075469017, 0.010050239972770214, -0.09248994290828705, -0.025373347103595734, 0.17282995581626892, 0.0005203831242397428, 0.010390229523181915, -0.054011162370443344, -0.03503862023353577, 0.006974313873797655, -0.0570213608443737, -0.010678363032639027, 0.03761087730526924, 0.04020705074071884, -0.06247184798121452, 0.04627969115972519, 0.00908877607434988, -0.02710697241127491, 0.030918924137949944, -0.03777753561735153, 0.003133184276521206, 0.03228446841239929, 0.00006081436004023999, -0.056121475994586945, 0.02502758987247944, 0.03447003662586212, 0.02698506973683834, 0.04205458611249924, -0.017229463905096054, -0.04646941274404526, 0.004079628270119429, -0.03066236525774002, -0.025951780378818512, -0.005087240133434534, 0.029074668884277344, 0.05738640949130058, 0.021341240033507347, -0.02677285484969616, -0.04300481081008911, 0.014104796573519707, 0.020040756091475487, -0.007175195496529341, 0.071943499147892, -0.019919700920581818, 0.1272686868906021, 0.025525830686092377, -0.06979106366634369, -0.006119504105299711, 0.008069171570241451, -0.09117254614830017, -0.07154499739408493, 0.05378304421901703, 0.05398732051253319, -0.0872550904750824, 0.04468731954693794, 0.0057776086032390594, 0.1026708260178566, 0.04453833028674126, -0.006258867215365171, 0.025473952293395996, -0.06279248744249344, 0.025048697367310524, -0.06731019914150238, -0.09198301285505295, -0.05313409864902496, -0.005982930306345224, -0.014525411650538445, -0.07016824185848236, -0.0437324158847332, 0.005980316083878279, -0.05658942461013794, 0.027392465621232986, -0.018218329176306725, -0.04494369029998779, 0.057466957718133926, 0.023693328723311424, -0.07325658202171326, -0.09428942203521729, -2.3551646453258712e-33, -0.007219355087727308, 0.0033526720944792032, -0.06378931552171707, 0.031197963282465935, -0.05128016695380211, -0.019579164683818817, 0.004492237698286772, -0.016736436635255814, 0.029093321412801743, -0.07248082756996155, 0.05708881840109825, 0.009517853148281574, 0.016623733565211296, -0.1093059554696083, -0.0378057137131691, 0.0510377362370491, 0.0064649032428860664, 0.04600038006901741, -0.025728436186909676, -0.027383793145418167, -0.0631299689412117, 0.008240166120231152, -0.046227507293224335, 0.08419835567474365, 0.05273071676492691, 0.004475331399589777, -0.02336377277970314, 0.006712202448397875, 0.020196914672851562, 0.03056417964398861, 0.050733622163534164, -0.04329400509595871, 0.0276381466537714, 0.020096462219953537, -0.006394134368747473, -0.005007872357964516, 0.0024522736202925444, 0.013918616808950901, -0.05405908077955246, 0.030045591294765472, 0.04683477059006691, -0.0000015017644727777224, 0.06294437497854233, 0.01807434670627117, -0.005270762834697962, 0.003579421667382121, -0.09817290306091309, -0.08375420421361923, -0.009832628071308136, 0.025119826197624207, 0.11554928123950958, -0.0019754997920244932, -0.0008892506593838334, -0.025452567264437675, 0.050133176147937775, 0.04293886572122574, -0.010431014932692051, -0.011846625246107578, -0.09551724791526794, 0.0193435437977314, 0.028818318620324135, 0.0016725449822843075, 0.04591069370508194, -0.045230090618133545, 0.10736197978258133, -0.05245568975806236, -0.12163437157869339, 0.017449624836444855, -0.05107041448354721, -0.05203889310359955, 0.059406451880931854, 0.011561532504856586, -0.07286152988672256, -0.08411185443401337, -0.0038376962766051292, -0.06774471700191498, 0.0805937647819519, -0.01391645148396492, -0.03445212543010712, -0.016976527869701385, 0.008812549524009228, 0.053623080253601074, 0.02083815447986126, 0.04875700920820236, -0.020656703040003777, -0.003045022487640381, 0.0004127059946767986, 0.00005854072514921427, 0.07967168092727661, 0.05761263519525528, 0.007421276997774839, 0.07522086799144745, -0.006722377147525549, 0.12626561522483826, 0.09120244532823563, -4.301325873257156e-8, -0.052890900522470474, -0.060991447418928146, -0.024045921862125397, 0.04764360561966896, 0.04489075765013695, 0.04141268506646156, 0.03733689337968826, 0.028911273926496506, -0.03234587237238884, -0.09575564414262772, 0.05224335566163063, 0.03930394724011421, -0.0928303524851799, -0.01191954780369997, 0.09965362399816513, 0.04228389263153076, -0.04446646571159363, 0.06134882941842079, -0.045081350952386856, -0.026061201468110085, 0.01953914761543274, 0.07947306334972382, 0.015161409974098206, 0.026302160695195198, -0.05299299582839012, -0.0315108560025692, -0.02368571050465107, 0.03506823629140854, 0.05256466567516327, 0.018181655555963516, 0.048750121146440506, -0.04154656454920769, -0.016546469181776047, -0.02208690159022808, 0.025689972564578056, 0.11323406547307968, -0.07488364726305008, -0.010562824085354805, -0.030087878927588463, 0.1276845484972, 0.012099015526473522, -0.0366121344268322, -0.056720342487096786, 0.058893270790576935, 0.039287321269512177, -0.06577826291322708, -0.07119318097829819, 0.08484316617250443, -0.04162200912833214, -0.04470343887805939, 0.004800859373062849, 0.1067095398902893, 0.03437018394470215, -0.014162988401949406, -0.02768993005156517, -0.001758328638970852, 0.04637958109378815, 0.04519539326429367, -0.020009279251098633, -0.04025242105126381, 0.052651192992925644, 0.05658278241753578, 0.10319795459508896, 0.02239372581243515 ]
TABLE\t14.13\nReported\tCravings\tand\tAversions\tby\tat\tLeast\t10%\tof\tPregnant\tWomen\tin\tPublished\tStudies\nCountry\nCravings\nAversions\nEthiopia\nMeat\tsauce,\tcheese,\tmilk\nWheat,\tcoffee,\twheat\tbread,\tmeat\nsauce\nTanzania\nMeat,\tmangoes,\tyogurt,\toranges\nRice,\tmeat,\tfish,\teggs\nNigeria\nCereals,\tvegetables,\tbeans,\tyams,\tcassava,\tplantain,
[ 0.031755995005369186, -0.007165555842220783, -0.03909842297434807, -0.05155690014362335, -0.10413681715726852, -0.010267678648233414, 0.032826390117406845, 0.019257348030805588, -0.026638053357601166, 0.06593593955039978, 0.09959748387336731, -0.07489696145057678, 0.04188709706068039, -0.00743850925937295, -0.0721934512257576, -0.0184877198189497, 0.01686517894268036, 0.029529688879847527, -0.054813697934150696, -0.018100013956427574, -0.004451480228453875, 0.07022928446531296, 0.030742499977350235, -0.0252144206315279, 0.07992993295192719, 0.042649343609809875, -0.054965581744909286, 0.03418218344449997, -0.012933182530105114, -0.07574212551116943, -0.14065539836883545, 0.0399920679628849, 0.026225777342915535, 0.029417403042316437, 0.08176183700561523, -0.03836473822593689, -0.06719573587179184, -0.005511285737156868, 0.0720803290605545, 0.05493885278701782, -0.01282130740582943, -0.06832271814346313, 0.0031941046472638845, 0.05639152601361275, 0.03505883365869522, -0.022373227402567863, -0.07745274156332016, 0.0076956902630627155, -0.018723690882325172, 0.0009311431203968823, -0.09195862710475922, 0.021878309547901154, -0.053353384137153625, 0.10910730808973312, 0.05477617308497429, -0.031059561297297478, -0.03875970095396042, -0.09015419334173203, -0.0326354056596756, 0.0017246550414711237, 0.006928334943950176, -0.006495750974863768, -0.04847908392548561, -0.000006996869615250034, -0.026650290936231613, 0.06535669416189194, -0.055538661777973175, 0.004237941931933165, -0.04046129807829857, 0.07056265324354172, -0.04291858151555061, 0.02778879925608635, -0.0706455186009407, 0.11985339224338531, -0.07770424336194992, 0.05807875096797943, 0.0879979357123375, -0.06977668404579163, 0.009123592637479305, -0.032548900693655014, -0.12077987194061279, 0.05081210285425186, -0.026864860206842422, 0.013355624862015247, -0.03219476342201233, -0.030405813828110695, 0.017100641503930092, 0.07299534231424332, 0.06709253042936325, 0.005426415242254734, 0.008499673567712307, -0.00481408229097724, 0.013061370700597763, -0.09221198409795761, -0.07458189129829407, 0.003983738366514444, 0.033859968185424805, -0.026612000539898872, 0.015700688585639, 0.019734911620616913, 0.01486919168382883, -0.014641365967690945, 0.04999375715851784, -0.025447120890021324, -0.11495447903871536, -0.006838848814368248, 0.043964240700006485, -0.025287965312600136, 0.08368419855833054, -0.043288134038448334, -0.051636409014463425, -0.004526262171566486, 0.00029840186471119523, -0.0792490765452385, -0.06123719736933708, -0.05396421626210213, -0.0012247500708326697, -0.026495233178138733, 0.1270277202129364, 0.0024932988453656435, 0.008882968686521053, -0.044602297246456146, -0.05323471873998642, 0.07889550924301147, -0.06722208112478256, -0.0026354282163083553, -0.032648373395204544, 2.0436345814579716e-33, 0.01702909544110298, 0.03817968815565109, 0.032171864062547684, 0.01106592733412981, 0.0772787481546402, -0.006741423159837723, -0.044887322932481766, -0.04948282614350319, -0.08666010946035385, 0.06198761612176895, -0.12727394700050354, -0.008235558867454529, -0.03724135458469391, 0.06513386219739914, 0.028736067935824394, -0.049354229122400284, -0.016222355887293816, 0.03893314674496651, -0.06769546121358871, -0.018940282985568047, -0.002455363282933831, 0.13626602292060852, 0.047229379415512085, 0.026566538959741592, -0.03911329433321953, -0.01386304385960102, -0.014287089928984642, -0.04990895092487335, -0.024753259494900703, 0.0423310212790966, 0.06624507158994675, -0.009573138318955898, -0.058480992913246155, -0.06043708324432373, -0.0073449090123176575, -0.00355905550532043, -0.014193136245012283, 0.005941444542258978, 0.08145329356193542, 0.0013238954124972224, -0.02972647175192833, 0.053650032728910446, 0.02734166942536831, 0.08944737911224365, 0.05291953682899475, -0.015370289795100689, 0.03501960262656212, 0.008049857802689075, 0.03153568506240845, -0.03509042412042618, -0.022783806547522545, -0.00931828934699297, 0.03168182820081711, 0.05238942801952362, -0.016751602292060852, 0.003855825634673238, 0.0013534965692088008, 0.08427193760871887, 0.00996173731982708, 0.08237791061401367, -0.036282993853092194, 0.04429323598742485, 0.04844817891716957, -0.055531587451696396, 0.040072325617074966, 0.023232994601130486, -0.10134708881378174, -0.02356121316552162, 0.04935123771429062, -0.017914526164531708, -0.03642116114497185, 0.014270802028477192, 0.004368312656879425, 0.049016743898391724, 0.055810391902923584, 0.03987617418169975, 0.0667901411652565, -0.08814812451601028, 0.02568417601287365, -0.11736713349819183, -0.03956696763634682, -0.022021565586328506, -0.023988159373402596, -0.08658052980899811, -0.1008310467004776, -0.03183588758111, 0.0156305730342865, -0.04153315722942352, 0.021843070164322853, -0.030523940920829773, -0.0470874048769474, 0.023183157667517662, 0.02369922585785389, -0.0730067566037178, -0.10981611907482147, -2.318314366795531e-33, -0.06025199964642525, -0.0032059194054454565, -0.039244361221790314, 0.036225080490112305, -0.02506367489695549, -0.06209329888224602, 0.015880582854151726, 0.0007694358937442303, 0.058416854590177536, -0.027599340304732323, 0.036007359623909, -0.007194917649030685, -0.0009994941065087914, -0.1248261034488678, -0.006443996913731098, 0.033136818557977676, 0.03092857263982296, 0.07468106597661972, -0.08449318259954453, -0.03218374773859978, -0.06518950313329697, 0.04525648429989815, -0.05999501049518585, 0.09773936867713928, 0.037708885967731476, 0.07714098691940308, -0.0208828616887331, -0.031201129779219627, 0.006585666909813881, 0.03064120188355446, -0.026317695155739784, -0.06113419681787491, 0.014365837909281254, 0.0686422660946846, -0.031249187886714935, -0.016068197786808014, 0.0488085076212883, -0.033387668430805206, -0.01361881848424673, 0.043726030737161636, 0.04323486611247063, -0.0003463833418209106, 0.09852710366249084, 0.06201711669564247, -0.003882582765072584, 0.020861199125647545, -0.016544800251722336, -0.05982941761612892, -0.03729010745882988, 0.013735910877585411, 0.0710945799946785, 0.04121734946966171, -0.030043676495552063, 0.03403628244996071, 0.06839105486869812, 0.015148501843214035, -0.008770343847572803, -0.04593151435256004, -0.08387084305286407, -0.04113403335213661, -0.022037142887711525, 0.03741704300045967, 0.08671656250953674, -0.00970774982124567, 0.09635424613952637, -0.05096185579895973, -0.09283103048801422, -0.049710728228092194, -0.018457971513271332, -0.025101564824581146, 0.01420447789132595, 0.01607355661690235, -0.06616514176130295, -0.10015834122896194, 0.058336786925792694, -0.012107166461646557, 0.005233066622167826, -0.038744471967220306, -0.019311459735035896, 0.01466136984527111, -0.01947992667555809, -0.00414280267432332, 0.06515093147754669, 0.0025180282536894083, 0.008719616569578648, -0.010954991914331913, 0.02813059464097023, 0.026507345959544182, 0.01227735634893179, 0.08541357517242432, -0.034186188131570816, 0.024332696571946144, 0.0256532933562994, 0.046239253133535385, 0.08944276720285416, -4.6884434112826057e-8, 0.0011587727349251509, -0.04877772182226181, -0.027360504493117332, 0.03716489300131798, 0.09308107942342758, -0.0599554069340229, 0.04041709005832672, 0.08131738752126694, 0.014962688088417053, -0.03781991824507713, 0.05583948642015457, 0.0708119198679924, -0.09142982959747314, -0.06404528021812439, 0.042017992585897446, 0.010000297799706459, 0.04691978916525841, 0.05513865500688553, -0.04099099338054657, -0.057359471917152405, -0.028181396424770355, 0.11938223242759705, -0.05759105086326599, -0.025080250576138496, -0.0258600153028965, 0.008572572842240334, -0.08506368845701218, 0.02227497659623623, 0.05536874756217003, -0.00597993191331625, 0.043889906257390976, -0.052116721868515015, 0.018226532265543938, -0.052221592515707016, 0.002946621971204877, 0.09356905519962311, -0.0640258640050888, -0.01242749486118555, 0.01392319519072771, 0.059356771409511566, -0.02187076397240162, -0.018258392810821533, -0.05203123018145561, 0.06289488077163696, 0.015160588547587395, -0.010209934785962105, -0.10457487404346466, 0.10722275823354721, -0.000845256436150521, -0.08904872834682465, -0.018751880154013634, 0.02404911443591118, 0.016026681289076805, -0.008336793631315231, -0.05036208778619766, 0.04175945743918419, 0.06746169179677963, 0.04000185430049896, 0.012519462034106255, 0.007856061682105064, 0.07366381585597992, 0.05260830372571945, 0.034330692142248154, -0.003986361902207136 ]
Nigeria\nCereals,\tvegetables,\tbeans,\tyams,\tcassava,\tplantain,\nnonalcoholic\tbeverages,\tfruits,\tmeats,\tmilk,\tfish\nAlcohol,\tplantains,\tcassava,\tyams,\nfish,\tmeat,\tmilk,\tnonalcoholic\nbeverages,\tbeans,\tfruits,\tcereals\nSouth\nAfrica\nFruits,\tsour\tfoods,\tsweets,\tcold\tdrinks\nMeat\nIraq\nMeat,\tchicken,\tmilk,\teggs,\tfruits,\tmilk\nMelons,\tonions,\tleeks,\tradishes,
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0.042339712381362915, 0.005058237351477146, 0.03386864811182022, 0.09229563176631927, -5.18216758393919e-8, 0.06162537261843681, -0.043969035148620605, -0.023566702380776405, 0.13938482105731964, 0.0712912529706955, -0.048088520765304565, -0.002564825350418687, -0.007884963415563107, 0.017219798639416695, -0.013131270185112953, -0.03953753039240837, 0.10396990180015564, -0.08484245836734772, -0.01278233528137207, 0.011949904263019562, -0.025092411786317825, 0.044802017509937286, 0.11606013774871826, 0.019451376050710678, -0.026358917355537415, -0.04152178391814232, 0.0395066924393177, -0.02045665867626667, -0.030896194279193878, 0.006517996545881033, -0.0729091465473175, -0.0430077500641346, -0.03697874769568443, 0.09853227436542511, 0.00619311211630702, 0.004266664851456881, -0.03473515436053276, -0.055724333971738815, -0.01610378734767437, 0.012325945310294628, 0.009910719469189644, -0.05423935502767563, -0.05420839786529541, -0.06067465618252754, 0.02122819609940052, -0.019620256498456, -0.0506572499871254, -0.03010728396475315, -0.011355925351381302, -0.0334986075758934, -0.016708223149180412, -0.04185175150632858, 0.12302984297275543, -0.020261667668819427, -0.037765078246593475, -0.040114231407642365, 0.04321341589093208, 0.006872841157019138, 0.016849903389811516, -0.008232218213379383, -0.001918309135362506, 0.0030779349617660046, -0.06315885484218597, 0.0355672761797905, -0.03722693398594856, 0.05593742057681084, 0.019210923463106155, 0.06378709524869919, 0.006642183754593134 ]
Melons,\tonions,\tleeks,\tradishes,\nspices\nSaudi\nArabia\nSalty\tfoods,\tsour\tfoods,\n\tmilk\nTea,\tcoffee,\tcola,\tmeat,\tspicy\tfoods\nItaly\nFruit,\tpasta\nMeat,\tsmoke,\tperfumes,\tcoffee\n(taste,\tsmell),\twhite\twine\nEngland\nFruit\tand\tfruit\tjuices,\tincluding\tcitrus,\tsweets,\tchocolate,\nbiscuits,\tice\tcream,\tmilk\tand\tmilk\tproducts,\tvegetables,
[ -0.008447086438536644, -0.06812599301338196, 0.00860251858830452, 0.015534580685198307, -0.06673257052898407, 0.0345265232026577, 0.0961746871471405, -0.0092247873544693, -0.009605460800230503, 0.00397057319059968, 0.1246204674243927, -0.08042622357606888, 0.043867919594049454, -0.04611926153302193, -0.00181313615757972, 0.012807944789528847, 0.09690700471401215, 0.034910306334495544, -0.06475702673196793, -0.0892586037516594, 0.04074113816022873, 0.06162506714463234, 0.06878300756216049, 0.021116288378834724, 0.023593053221702576, 0.0177768561989069, -0.04001397639513016, -0.04882266744971275, -0.03821751847863197, -0.05771753564476967, -0.054641298949718475, 0.036123961210250854, 0.05348304286599159, 0.009595616720616817, 0.02380203641951084, -0.017778033390641212, -0.058864276856184006, -0.023500332608819008, 0.06567458063364029, -0.01177147589623928, 0.015545145608484745, -0.027695534750819206, 0.018850572407245636, -0.0035844454541802406, -0.013589070178568363, 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biscuits,\tice\tcream,\tmilk\tand\tmilk\tproducts,\tvegetables,\nsweet\tmeats,\tliquids,\tmeats\nTea,\tcoffee,\thighly\tflavored\tor\tspicy\nfoods,\tincluding\tcurries,\tmeats,\nfish,\teggs,\tsmell\tof\tfried\tor\tfatty\nfoods,\tcigarette\n\tsmoke/tobacco,\ncocoa,\tvegetables\nEcuador\nFruit\tand\tfruit\tjuices,\tmeat,\tpoultry,\tfish\tand\tseafood,\teggs\nMeat,\tpoultry,\tfish,\tseafood,
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Meat,\tpoultry,\tfish,\tseafood,\nchicken\tand\tquail\teggs,\nvegetables,\twhite\trice,\twheat\nnoodles,\tcorn,\tbarley\nJamaica\nWater,\tice,\tmilk\tand\tmilk\tdrinks,\tfruit\tand\tfruit\tjuices,\nvegetables,\tsweet\tdrinks,\tmeats,\tfish\nMeat,\trice,\twheat\tdumplings,\tyams,\nmilk,\tfruit\tand\tfruit\tjuices,\tsweet\ndrinks,\n\tfish\nUnited\nStates
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0.013491934165358543, -0.011349408887326717, 0.028915053233504295, 0.14525744318962097, -4.406023634828671e-8, 0.07026100903749466, -0.036040421575307846, -0.040798868983983994, 0.08339555561542511, 0.046918485313653946, -0.055269792675971985, 0.060658980160951614, 0.00047561925021000206, 0.025378182530403137, -0.019308140501379967, -0.01716931350529194, 0.13802194595336914, -0.06411094218492508, -0.037944477051496506, 0.012792649678885937, 0.01966754160821438, 0.016605548560619354, 0.026653055101633072, -0.002134967828169465, -0.059016238898038864, -0.0401514396071434, 0.052901167422533035, -0.06372927874326706, -0.032766230404376984, -0.029970837756991386, -0.05784821882843971, -0.062459710985422134, -0.024524735286831856, 0.11453176289796829, 0.018438128754496574, 0.029332982376217842, -0.030301708728075027, -0.03165057674050331, 0.00309966504573822, 0.02174973674118519, 0.048758912831544876, -0.09840909391641617, 0.005247483029961586, 0.011177929118275642, 0.07307326793670654, -0.06979971379041672, 0.0344119668006897, -0.05883491411805153, 0.04484753683209419, 0.0031625234987586737, -0.01618833653628826, -0.07519450783729553, 0.09488708525896072, 0.017304295673966408, -0.04672243073582649, -0.0416865311563015, 0.0448920764029026, 0.01509114820510149, -0.018707554787397385, -0.031904395669698715, 0.06131923571228981, 0.0634201169013977, -0.031242946162819862, 0.007309006992727518, 0.01698005385696888, 0.04285536706447601, 0.032797880470752716, 0.07594101876020432, 0.01326986588537693 ]
milk,\tfruit\tand\tfruit\tjuices,\tsweet\ndrinks,\n\tfish\nUnited\nStates\nSweets,\tchocolate,\tfruit\tand\tfruit\tjuice,\tcitrus,\tpickles,\tice\ncream,\tice\tmilk,\tpizza,\tbeef,\tchips,\tspicy\tfoods,\traw\nvegetables,\tmilk\tand\tother\tdairy,\tfish,\tethnic\tfoods,\nmeat,\tgrains,\tnuts\tand\tnut\tbutters,\tsalty\tfoods,\tcookies,\nItalian\tsauce,\tbreads/cereals
[ -0.049089763313531876, -0.04141632094979286, 0.02149185538291931, 0.03758135065436363, -0.03542422875761986, 0.01024023536592722, 0.08643882721662521, -0.005202924832701683, -0.05863722413778305, -0.018379954621195793, 0.11821407079696655, -0.05407026410102844, 0.05733487755060196, -0.02588851936161518, 0.0024738330394029617, 0.0023728027008473873, 0.08094345033168793, 0.034403614699840546, -0.05516085773706436, -0.07594891637563705, 0.05206424370408058, 0.037400297820568085, 0.028964228928089142, 0.01845277100801468, 0.045784030109643936, 0.027241196483373642, -0.028495358303189278, -0.03438515588641167, -0.047070086002349854, -0.05731606483459473, -0.06858979910612106, 0.03223099187016487, 0.06400825083255768, -0.008802724070847034, 0.05151500925421715, 0.010408644564449787, -0.04346200078725815, -0.04791108891367912, 0.05064534395933151, 0.010958408005535603, 0.027228184044361115, -0.06596656143665314, -0.0044439067132771015, 0.014318276196718216, 0.0053342715837061405, 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Italian\tsauce,\tbreads/cereals\nMeat,\tbeef,\tfish,\teggs,\tvegetables,\nethnic\tfoods,\tgreasy\tfoods,\ncoffee,\ttea,\tlegumes,\talcohol,\ngrains,\tsweets,\tfruits,\n\tcigarettes,\nItalian\tsauce,\tspicy\tfoods\nAdapted\tfrom.\tPatil\tCL,\tAbrams\tET,\tSteinmetz\tAR,\tet\tal:\tAppetite\tsensations\tand\tnausea\tand\tvomiting\tin\tpregnancy:\tan\toverview\tof\tthe\nexplanations,
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explanations,\t\nEcol\tFood\tNutr\n\t51:394,\t2012.\nPica.\nConsumption\tof\tnonfood\tsubstances\tor\tfood\titems\tin\tnonphysiologic\tamounts\t(\npica\n)\tduring\npregnancy\tmost\toften\tinvolves\t\ngeophagia\n\t(consumption\tof\tdirt\tor\tclay),\t\namylophagia\n\t(laundry\nstarch,\tcorn\tstarch,\tor\tuncooked\trice),\tor\t\npagophagia\n\t(ice).\tOther\tsubstances\tinclude\tpaper,\tburnt
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pagophagia\n\t(ice).\tOther\tsubstances\tinclude\tpaper,\tburnt\nmatches,\tstones\tor\tgravel,\tcharcoal,\trock\tsalt,\tbleach,\tcigarette\tashes,\tbaby\tpowder,\tbaking\tsoda,\nsoap,\ttires,\tand\tcoffee\tgrounds.\tAlthough\tsome\tof\tthe\tcommon\tsubstances\tare\tof\tlittle\tconcern,\nothers\tare\tdangerous\tto\tthe\tmother.\tThe\tlocal\tpoison\tcontrol\tcenter\tcan\tgive\tguidance\ton\twhich
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0.11802128702402115, 0.03562139347195625, 0.031919632107019424, -0.007958558388054371, 0.0645938515663147, 0.026964176446199417, 0.015202145092189312, -0.02822103537619114, 0.0348471961915493, 0.05315075069665909, -0.05663343891501427, -0.024119539186358452, 0.09156867861747742, 0.0117909861728549, -0.05432795360684395, 0.010763144120573997, 0.08571586012840271, 0.02585900016129017, 0.06876280903816223, -0.029740409925580025, 0.015775321051478386, 0.037451598793268204, 0.08045193552970886, 0.05590426176786423, -0.011996489018201828 ]
require\timmediate\tintervention.\nPica\tis\tcommon\tin\tpregnancy,\tand\tthe\tincidence\tof\tpica\tin\tthe\tUnited\tStates\tis\testimated\tto\tbe\t14%\nto\t44%,\twith\twide\tvariability\tbetween\tgroups\t(\nScolari\tChildress\tand\tMyles,\t2013\n).\tPica\tis\tnot\tlimited\nto\tany\tone\tgeographic\tarea,\trace,\tculture,\tor\tsocial\tstatus,\tbut\tthere\tare\tcultural\tcomponents\trelated
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0.07328896969556808, 0.01949949562549591, 0.07634925097227097, 0.0978236123919487, -5.0629406445068525e-8, -0.025699317455291748, -0.04518042877316475, 0.0160587877035141, -0.025967277586460114, 0.04534601420164108, -0.024332718923687935, 0.12005648016929626, -0.015086761675775051, -0.016081130132079124, -0.10164729505777359, -0.001723196473903954, 0.08214528113603592, -0.08283447474241257, -0.05635679513216019, 0.09272093325853348, 0.0438525415956974, -0.002382830949500203, 0.09069422632455826, -0.051020532846450806, -0.052037376910448074, 0.0037015678826719522, 0.09879130870103836, -0.04842135310173035, -0.008404120802879333, -0.05541864037513733, 0.007874850183725357, -0.036269281059503555, 0.023513052612543106, 0.026283925399184227, 0.017048431560397148, 0.020477794110774994, -0.04667472094297409, 0.017057515680789948, -0.07034309953451157, -0.026985609903931618, 0.06555017083883286, -0.031918417662382126, -0.043115727603435516, 0.004457590635865927, 0.10496965795755386, 0.04186207056045532, 0.011571425944566727, -0.04883747175335884, 0.06068868190050125, 0.12259992957115173, -0.08419696986675262, -0.008741859346628189, 0.018887655809521675, -0.03945528343319893, -0.007538688834756613, -0.021307356655597687, 0.08393897861242294, -0.020892681553959846, -0.037102799862623215, -0.058437734842300415, 0.01819523423910141, 0.04452001303434372, 0.04391414299607277, -0.039697468280792236, 0.043041668832302094, 0.05262910947203636, 0.06231960281729698, 0.09315267205238342, -0.030622471123933792 ]
to\tthe\tsubstances\tchosen\tand\tthe\tacceptability\tof\tdisclosure.\n\tPreferred\tsubstances\toften\tare\nimported\tfrom\thome\tcountries,\tincluding\tsoil\tor\tclay\tand\tblocks\tof\tmagnesium\tcarbonate.\nThe\tcause\tof\tpica\tis\tpoorly\tunderstood.\tOne\ttheory\tsuggests\tthat\tpica\trelieves\tnausea\tand
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vomiting,\talthough\tpica\toften\tappears\tlater\tin\tpregnancy\twhen\tnausea\tand\tvomiting\tare\tnot\tso\nprevalent.\tOne\thypothesis\tis\tthat\tit\tis\tdue\tto\ta\tdeficiency\tof\tan\tessential\tnutrient,\tmost\toften\n\tiron,\nbut\tzinc,\tcalcium,\tand\tpotassium\talso\thave\tbeen\tmentioned\t(\nCardwell,\t2013\n).\tAlthough\tit\tis
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Cardwell,\t2013\n).\tAlthough\tit\tis\nhypothesized\tthat\tthe\tcraving\tcauses\tone\tto\teat\tthe\tnonfood\tsubstance\tthat\tcontains\tthe\tmissing\nnutrients,\tthat\tis\tseldom\tthe\tcase.\tPica\talso\tcan\tbe\ta\tcraving\tfor\tsmell\tor\ttexture\tas\twell\tas\ttaste.\tIDA\nhas\tbeen\tassociated\twith\tthe\tolfactory\tcraving\tin\tpica\t(\nHansen\tet\tal,\t2017\n)\tand\tchewing\tice\thas\tbeen
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Hansen\tet\tal,\t2017\n)\tand\tchewing\tice\thas\tbeen\nshown\tto\timprove\talertness\tand\tresponse\ttimes\ton\ta\tneuropsychological\ttest\tfor\tpeople\twho\tare\nanemic\tbut\tnot\tfor\tothers\t(\nHunt\tet\tal,\t2014\n).\tTaste\tperceptions\toften\tchange,\tbut\twhether\tthat\tis\nassociated\twith\tlower\tzinc\tlevels\tis\tnot\tknown.
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0.022014396265149117, -0.048119015991687775, 0.007153880316764116, -0.02520238421857357, -0.020566366612911224, 0.021698439493775368, 0.09455721825361252, 0.03566312789916992, -0.017783036455512047, 0.10810472071170807, -0.09304624795913696, -0.020135756582021713, -0.09315335005521774, -0.03207029402256012, -0.026316052302718163, 0.0055366759188473225, 0.06548427790403366, -0.05969202145934105, -0.03965241089463234, -0.047427888959646225, 0.02046041004359722, -0.10099311918020248, 0.08242285251617432, 0.011454308405518532, 0.09079010039567947, 0.014863207004964352, -0.014575564302504063, -0.022766970098018646, 0.042794350534677505, -0.01613197848200798, -0.01441340334713459, -0.04107736796140671, 0.030453959479928017, -0.009433593600988388, 0.035663265734910965, 0.015771877020597458, -0.010759467259049416, -0.10591215640306473, -0.012553849257528782, 0.07962154597043991, -0.013438177295029163, 0.050728101283311844, -0.0011306864907965064, 0.017522873356938362, -0.01817936822772026, -0.10880248993635178, -0.04459310695528984, -0.008260561153292656, 0.02641015686094761, 0.10641250014305115, 0.016266096383333206, -0.03871754929423332, -0.005028154235333204, 0.032032765448093414, -0.01662016473710537, -0.023723822087049484, -0.07751987874507904, -0.07221726328134537, 0.019847700372338295, -0.0034540232736617327, 0.004496467765420675, 0.03560960665345192, 0.036982160061597824, 0.07470967620611191, -0.04115961119532585, -0.13100504875183105, -0.0214539747685194, -0.005331011954694986, -0.011772350408136845, 0.024276966229081154, 0.008819112554192543, -0.08745157718658447, -0.13353252410888672, 0.10921533405780792, -0.014061854220926762, 0.010400120168924332, -0.01522256899625063, -0.05643235146999359, -0.028460083529353142, -0.014177165925502777, -0.04262702539563179, 0.07308091968297958, 0.10881496220827103, 0.015940850600600243, -0.005458796862512827, -0.0037844430189579725, 0.01669478416442871, 0.02142312377691269, 0.07566317915916443, -0.035464853048324585, 0.07363854348659515, -0.013896502554416656, 0.09094588458538055, 0.1029672622680664, -5.5433972079299565e-8, -0.007556830998510122, -0.03695525601506233, 0.010393754579126835, -0.0413038544356823, 0.07543212920427322, 0.016716988757252693, 0.004886512644588947, -0.006713636219501495, -0.06431525945663452, -0.027036970481276512, 0.024079712107777596, 0.0741380900144577, -0.07746337354183197, -0.006328505463898182, 0.05729790776968002, -0.009426889009773731, -0.01926533319056034, 0.10163495689630508, -0.017645811662077904, -0.058667976409196854, 0.015319311991333961, 0.08050461113452911, 0.00756607111543417, -0.03569870442152023, -0.01800260692834854, 0.05546672269701958, -0.03806275129318237, 0.013810460455715656, 0.02949397824704647, -0.006541315466165543, 0.033349838107824326, -0.05041749030351639, 0.0114423343911767, -0.019035005941987038, 0.031653858721256256, 0.0668475329875946, -0.07884230464696884, -0.036388128995895386, -0.049631379544734955, 0.09053756296634674, 0.004988060798496008, 0.030815489590168, 0.017384301871061325, 0.11486651003360748, 0.05650465562939644, -0.0950407087802887, -0.04251370206475258, 0.07092177122831345, -0.0013997242785990238, -0.06989814341068268, -0.017089245840907097, 0.0594426691532135, -0.0003261812962591648, -0.0017811862053349614, -0.050903234630823135, 0.04535027593374252, 0.08892595767974854, 0.05036867782473564, -0.05947629362344742, 0.023091662675142288, 0.10239925980567932, 0.046604596078395844, 0.048119720071554184, 0.009741594083607197 ]
associated\twith\tlower\tzinc\tlevels\tis\tnot\tknown.\nMalnutrition\tcan\tbe\ta\tconsequence\tof\tpica\twhen\tnonfood\tsubstances\tdisplace\tessential\tnutrients\tin\nthe\tdiet.\tStarch\tin\texcessive\tamounts\tcontributes\tto\tobesity\n\tand\tcan\tnegatively\taffect\tglucose\ncontrol.\tLarge\tintakes\tof\tbaking\tsoda\tcan\traise\tblood\tpressure\tand\textreme\tdoses\t(1\tbox/day)\thave
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0.05796177312731743, -5.299732208641217e-8, -0.04691082239151001, -0.08876050263643265, 0.008116236887872219, 0.0034664145205169916, 0.04978517070412636, -0.015584127977490425, 0.08307373523712158, 0.05931450426578522, -0.015690991654992104, -0.044670142233371735, 0.030921954661607742, 0.0880078449845314, -0.07454311847686768, -0.051045797765254974, 0.04389785975217819, 0.022794190794229507, -0.017204519361257553, 0.055394306778907776, -0.023671375587582588, -0.06825123727321625, 0.03303230553865433, 0.07001776248216629, -0.02394198067486286, -0.0009497231221757829, 0.002357067074626684, -0.02460802160203457, -0.02699119597673416, 0.038872696459293365, 0.053408846259117126, -0.010183562524616718, 0.06826487928628922, -0.06577210128307343, 0.008454270660877228, -0.02999870665371418, -0.02833463065326214, 0.02156481333076954, -0.056255001574754715, -0.009048971347510815, -0.05425000563263893, 0.14130111038684845, -0.03111731819808483, 0.006584918592125177, -0.01868261769413948, 0.08197879046201706, 0.06794726103544235, -0.04206189513206482, -0.04490123689174652, 0.09941740334033966, 0.00526251457631588, -0.06475649029016495, 0.017814746126532555, 0.1012820154428482, 0.007808242458850145, -0.02581172250211239, -0.09570696949958801, 0.043917473405599594, 0.08247487992048264, 0.039183273911476135, 0.002747213002294302, -0.025668278336524963, -0.002686721971258521, 0.09237965941429138, 0.04158097878098488, -0.03130248561501503 ]
caused\trhabdomyolysis\tand\tcardiomyopathy\t(\nScolari\tChildress\tand\tMyles,\t2013\n).\tExcessive\tintakes\nof\tbaking\tpowder\tcan\tmimic\tpreeclampsia.\tSubstances\tmay\tcontain\ttoxic\tcompounds\tor\theavy\nmetals,\tparasites,\tor\tother\tpathogens.\tThe\tabsorption\tof\tiron\tor\tother\tminerals\n\tmay\tbe\tdisrupted.
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may\tbe\tdisrupted.\nExcessive\tgeophagia\tcan\tresult\tin\tintestinal\tobstruction\tor\tperforation\t(\nYoung,\t2011\n).\nRecommending\tstopping\ta\tpica\toften\tfails,\teither\tbecause\tof\tthe\tstrong\tphysiologic\tdrive\tor\tthe\ncultural\tperception\tthat\tnot\tcomplying\twith\tthe\tcraving\twill\tcause\tharm\tto\tthe\tfetus.\tRather\tthan
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insisting\ton\tcessation,\tresulting\tonly\tin\tless\twillingness\tto\tadmit\tthe\tpica,\ta\tmore\tproductive\napproach\tis\tto\toffer\ta\tbetter\talternative.\tFor\texample,\tallowing\tthe\tmother\tto\tcontinue\tto\tsmell\tthe\nwet\tdirt,\tbut\ttrading\tits\tconsumption\tfor\ta\tburned\ttortilla,\ttoast,\tor\tjicama\toften\tis\tsuccessful.\tPica
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often\tis\tassociated\twith\tIDA,\tbut\twhether\tthe\tpica\tis\ta\tresult,\ta\tcause,\tor\ta\tmarker\tof\tother\nconcurrent\tdeficiencies\tis\tunknown.\tHowever,\ttreatment\twith\tvery\thigh\tiron\tfoods\toften\tdecreases\nthe\n\tcravings\tand\tinfusions\tof\tiron\thave\tresulted\tin\ta\tcessation\tof\tthe\tpagophagia,\tas\twell\tas\trestless\nlegs\t(\nAuerbach\tand\tAdamson,\t2016\n).\nDiabetes\tmellitus
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legs\t(\nAuerbach\tand\tAdamson,\t2016\n).\nDiabetes\tmellitus\nGestational\tdiabetes\tmellitus\t(GDM)\n,\tcarbohydrate\tintolerance\twith\tonset\tor\trecognition\tduring\npregnancy,\tencompasses\ttwo\tdistinct\tgroups—those\twho\thave\tunrecognized\tpreexisting\tdiabetes\nand\tthose\tfor\twhom\tthe\tpregnancy\tprecipitates\tthe\tcarbohydrate\n\tintolerance.
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intolerance.\nWomen\twith\trisk\tfactors\tfor\ttype\t2\tdiabetes\t(including\tbut\tnot\tlimited\tto\ta\thistory\tof\tGDM,\tknown\nimpaired\tglucose\tmetabolism,\tand\tBMI\t≥30)\tshould\tbe\tscreened\tearly\tin\tpregnancy\tusing\tstandard\ndiagnostic\tcriteria\t(\nACOG,\t2018c\n;\t\nAmerican\tDiabetes\tAssociation\t[ADA],\t2019\n;\tsee\t\nChapter\t29\n).
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;\t\nAmerican\tDiabetes\tAssociation\t[ADA],\t2019\n;\tsee\t\nChapter\t29\n).\nAccording\tto\tthe\tADA,\tthose\twomen\tidentified\twith\tdiabetes\tin\tthe\tfirst\ttrimester\tshould\tbe\tgiven\n\ta\ndiagnosis\tof\tovert\tdiabetes\trather\tthan\tGDM.\tUniversal\tscreening\twith\ta\themoglobin\tA1C\tat\tthe\tfirst\nprenatal\tvisit\tis\tcommon\tand\twill\toften\tidentify\tthese\tpeople.
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prenatal\tvisit\tis\tcommon\tand\twill\toften\tidentify\tthese\tpeople.\nWomen\tidentified\tby\tearly\tscreening,\tas\twell\tas\tthose\twith\tknown\tpreexisting\tdiabetes\t(either\ttype\n1\tor\t2),\tshould\tbe\treferred\tto\ta\tCertified\tDiabetes\tEducator\t(CDE)\tand/or\ta\tdiabetes\tmanagement\nteam.\tFetuses\tof\tmothers\twith\tpoorly
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team.\tFetuses\tof\tmothers\twith\tpoorly\n\tcontrolled\tdiabetes\tat\tconception\tare\tat\trisk\tfor\tmultiple\ncongenital\tanomalies.\tSee\t\nChapter\t29\n\tfor\tmanagement\tguidelines.\nAs\tpregnancy\tprogresses\tand\tinsulin\tresistance\tincreases,\tGDM\tresulting\tfrom\tthe\tpregnancy\tmay
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0.004333679564297199, 0.0024425999727100134, 0.06663498282432556, 0.09014519304037094, 0.05244630202651024, -0.07530110329389572, -0.012784035876393318, 0.08765243738889694, 0.008777573704719543, -0.08733250945806503, -0.015393885783851147, 0.03996709734201431, -0.03389186039566994, -0.011765308678150177, -0.05490012466907501, 0.012267408892512321, 0.0905364528298378, 0.07103879749774933, -0.02612043172121048, 0.032024797052145004, 0.10724212229251862, 0.014163320884108543, 0.07977040857076645, 0.009922702796757221 ]
relative\twith\tdiabetes).\tRates\tare\thigher\tamong\tAfrican\tAmerican,\tAsian,\tHispanic,\tNative\tAmerican,\nand\tPacific\tIslander\twomen\tcompared\twith\tnon-Hispanic\twhite\twomen\t(\nACOG,\t2018c\n).\nA\tdiagnosis\tof\tGDM\tis\tassociated\twith\tincreased\trisk\tof\tgestational\thypertension\tand\tof\npreeclampsia,\tas\twell\tas
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preeclampsia,\tas\twell\tas\n\tincreased\trisk\tof\ttype\t2\tdiabetes\tand\tCVD\tlater\tin\tlife.\tFetal\timplications\ninclude\thyperinsulinemia,\t\nmacrosomia\n\t(often\tdefined\tas\ta\tbaby\tweighing\tmore\tthan\t4000\tg),\tand,\ntherefore,\tincreased\trisk\tof\tdelivery\tcomplications,\tincluding\tshoulder\tdystocia\tand\tcesarean
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delivery.\tThe\tneonate\tis\tmore\tlikely\tto\trequire\tadmission\tto\tNICU\tand\tto\texperience\trespiratory\ndistress\tsyndrome\tand\tmetabolic\tcomplications,\n\tincluding\thyperbilirubinemia\tand\thypoglycemia.\nInfant\tiron\tlevels\tmay\tbe\tlower\tbecause\tof\tovergrowth\tand\ttherefore\tincreased\tdemand\t(\nMonk\tet\tal,\n2013
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Monk\tet\tal,\n2013\n).\tOther\tnutrients\talso\tmay\tbe\tlow.\tFetal\tprogramming,\twith\tincreased\tlong-term\trisk\tof\tobesity\nand\ttype\t2\tdiabetes,\tis\talso\tof\tconcern.\nAlthough\tsome\tpractitioners\tbelieve\tthat\tGDM\tmay\trepresent\tthe\tearly\tstages\tof\ttype\t2\tdiabetes,\nothers\tfeel\tthat\n\twomen\tshould\tnot\tbe\tlabeled\tat\tall\twith\ta\tGDM\tdiagnosis.\tHowever,\ttreatment\tfor
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GDM\tis\tmerited\tbecause\tit\tlowers\tthe\trisk\tby\t40%\tfor\tgestational\thypertensive\tdisorders,\treduces\nthe\trisk\tof\tmacrosomia,\tand\ttherefore\treduces\tthe\trisk\tof\tshoulder\tdystocia\tfrom\t3.5%\tto\t1.5%\t(\nNIH,\n2013\n).\nThe\tdiagnostic\tcriteria\tfor\tGDM\tare\tcontroversial.\tHistorically,\tthe\tUnited\tStates\tand\tother\ncountries\thave\tused
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countries\thave\tused\n\ta\ttwo-step\tprocess,\twhereas\tthe\tWHO\thas\tadvocated\ta\tone-step\tapproach.\t\nTable\n14.14\n\tsummarizes\tselected\tcurrent\tguidelines\tbut\tother\tcutoffs\tand\ttesting\tprotocols\talso\texist\n(\nAgarwal,\t2015\n).\tRecently\tthe\tInternational\tAssociation\tof\tthe\tDiabetes\tand\tPregnancy\tStudy\tGroups
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0.05273564159870148, 0.038337159901857376, -0.00939431693404913, 0.1085638552904129, 0.021632200106978416, -0.05744970217347145, -0.04618610069155693, 0.043214648962020874, -0.05268707126379013, -0.05904636159539223, -0.07326799631118774, 0.08586990833282471, 0.004647932015359402, -0.06411182880401611, -0.01169275026768446, 0.0775492936372757, 0.0953783392906189, -0.0016688761534169316, 0.04862545430660248, 0.06756745278835297, 0.10281463712453842, 0.04608497396111488, 0.04248811677098274, -0.000031909974495647475 ]
(IADPSG)\tadvocated\tfor\ta\tuniversal\tone-step\tapproach\tdeveloped\tfrom\tthe\tHyperglycemia\tand\nAdverse\tPregnancy\tOutcomes\t(HAPO)\n\ttrials.\tAll\tprevious\tprotocols\twere\tdesigned\tto\tidentify\twomen\nat\trisk\tof\tdeveloping\ttype\t2\tdiabetes\tlater\tin\tlife\twhile\tthe\tHAPO\tstudy\twas\tthe\tfirst\tto\tcorrelate
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glucose\tvalues\twith\tpregnancy\toutcomes.\tBecause\tonly\tone\televated\tvalue\tis\tdiagnostic,\tusing\tthe\nmore\tliberal\tIADPSG\tcriteria\tresults\tin\ta\ttwofold\tto\tthreefold\tincrease\tin\tthe\tnumber\tof\tpeople\ndefined\tas\thaving\tGDM,\tarriving\tat\ta\tnational\n\tprevalence\tof\t15%\tto\t20%\t(\nNIH,\t2013\n).
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TABLE\t14.14\nScreening\tand\tDiagnosis\tof\tGestational\tDiabetes\tMellitus\t(GDM)\tat\t24\tto\t28\tWeeks\tof\tGestation:\tBlood\nGlucose\tThresholds\tand\tTesting\tProtocols\nApproach\nFasting\nmg/dL\n1-hour\nmg/dL\n2-hour\nmg/dL\n3-hour\nmg/dL\nSource\nTWO\tSTEP:\n\tuniversal\tscreening;\nonly\tthose\t≥\tcutoff\tneed\ndiagnostic\ttest\nScreening:\n\t(nonfasting)\n50\tg\tglucose\tload,\tvalue\t≥
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0.09174104779958725, 0.029372721910476685, -4.846107160005886e-8, 0.008783659897744656, -0.07552310824394226, 0.021608658134937286, -0.019767679274082184, 0.02857300639152527, -0.07255806028842926, 0.03350386768579483, 0.06397727131843567, 0.007110937498509884, -0.08015765994787216, 0.07560580223798752, 0.048209238797426224, -0.03929230570793152, -0.05114254727959633, 0.0430753231048584, 0.017638636752963066, -0.015034671872854233, 0.03504309803247452, -0.03716767951846123, -0.07751886546611786, 0.021148044615983963, 0.061062805354595184, -0.009273402392864227, 0.010754769667983055, -0.018466677516698837, 0.03909406438469887, 0.013428525999188423, 0.01156435627490282, 0.054994262754917145, 0.007044053170830011, 0.05853680521249771, -0.0331510491669178, 0.026665564626455307, 0.020745569840073586, 0.009141985327005386, -0.016880149021744728, 0.004319863393902779, -0.010998870246112347, 0.009812375530600548, 0.11734090745449066, -0.032329559326171875, -0.01021957490593195, 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diagnostic\ttest\nScreening:\n\t(nonfasting)\n50\tg\tglucose\tload,\tvalue\t≥\n130,\t135,\nor\t140\nDiagnosis:\n\t(fasting)\n100\tg\tload,\t2\tvalues\t≥\n95\n180\n155\n140\nCarpenter\tand\nCoustan\n100\tg\tload,\t2\tvalues\t≥\n105\n190\n165\n145\nNational\tDiabetes\nData\tGroup\nONE\tSTEP:\n\tuniversal\ttesting\nDiagnosis:\n\t(fasting)\n92-125\n*\n180\n153-199\n*\nWorld\tHealth\nOrganization\n(WHO)\n**
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(fasting)\n92-125\n*\n180\n153-199\n*\nWorld\tHealth\nOrganization\n(WHO)\n**\n75\tg\tload,\t1\tvalue\t≥\n75\tg\tload,\t1\tvalue\t≥\n92\n180\n153\nInternational\nAssociation\tof\tthe\nDiabetes\tand\nPregnancy\tStudy\nGroups\n*\nValues\tabove\tthese\tcutpoints\tare\tconsidered\tdiagnostic\tof\tdiabetes\tmellitus\tin\tpregnancy\trather\tthan\tGDM,\tas\tis\ta\trandom\tplasma\tvalue\tof\t≥\t200\nmg/dL\twith
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mg/dL\twith\n\tdiabetes\tsymptoms.\n**\nConsidered\tdiagnostic\tof\tGDM\twhen\tfound\tany\ttime\tduring\tthe\tpregnancy.\nAdapted\tfrom\tNational\tInstitutes\tof\tHealth\tconsensus\tdevelopment\tconference\tstatement:\tdiagnosing\tgestational\tdiabetes\tmellitus,\tMarch\t4-6,\n2013,\t\nObstet\tGynecol
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2013,\t\nObstet\tGynecol\n\t122:358,\t2013;\tWorld\tHealth\tOrganization:\tWHO\trecommendation\ton\tthe\tdiagnosis\tof\tgestational\tdiabetes\tin\tpregnancy,\nMarch\t8,\t2018\t(website):\t\nhttps://extranet.who.int/rhl/topics/preconception-pregnancy-childbirth-and-postpartum-care/antenatal-care/who-\nrecommendation-diagnosis-gestational-diabetes-pregnancy-0\n.
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0.03385234624147415, 0.011412093415856361, 0.10331187397241592, 0.06011864170432091, 0.01457509770989418, -0.05419196933507919, 0.04967565834522247, 0.07737721502780914, -0.006968420464545488, -0.01398112066090107, -0.10152977705001831, 0.03187955915927887, 0.037124067544937134, 0.0301243644207716, 0.028916707262396812, 0.08993848413228989, -0.021066902205348015, -0.02839038148522377, 0.027523815631866455, 0.024550948292016983, 0.025068137794733047, -0.027333054691553116, 0.08034875243902206, 0.013552801683545113 ]
recommendation-diagnosis-gestational-diabetes-pregnancy-0\n.\nBecause\tof\tthe\tincreased\tcost\tto\tthe\tmedical\tsystem\tand\tthe\tpatient,\tincreased\tpatient\tstress\twith\nlikely\tincreased\tinterventions,\tcombined\twith\tconcern\tthat\ttreatment\tmay\tnot\tbe\tas\tbeneficial\tfor\nthose\tat\tthe\tlower\tglucose\tlevels,\ta\tNIH\tconsensus\tcommittee\tconcluded\tthere\tis\tcurrently
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-0.010879104025661945, 0.019473860040307045, 0.08187972754240036, 0.02911941334605217, -0.03582681342959404, 0.04824664816260338, 0.03543448820710182, 0.03364119306206703, -0.038579702377319336, -0.006461259908974171, 0.053343161940574646, 0.03198014572262764, -0.040067560970783234, 0.004563071299344301, 0.10492141544818878, 0.06201929971575737, 0.024882420897483826, 0.001969746081158519, -0.04680322855710983, 0.09217947721481323, 0.09622751176357269, 0.06323754042387009, 0.01725887320935726 ]
insufficient\tevidence\tto\trecommend\tchanging\tto\tthe\tIADPSG\tapproach\t(\nNIH,\t2013\n).\tThose\tconcerns\nhave\tnow\tbeen\n\tstudied\tand\tsome\tpractices\thave\treturned\tto\tusing\tthe\ttwo-step\tapproach\tafter\nfinding\tno\timprovement\tin\tmaternal\tor\tneonatal\toutcomes\tin\tspite\tof\tincreased\tdiagnoses\tand\ninterventions\t(\nPocobelli\tet\tal,\t2018\n).
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interventions\t(\nPocobelli\tet\tal,\t2018\n).\nThe\tADA\tand\tACOG\trecommend\tscreening\tall\tpregnant\twomen\tfor\tGDM\t(unless\talready\tidentified\nwith\tdiabetes)\tat\t24\tto\t28\tweeks\tof\tgestation\t(\nACOG,\t2018c\n;\t\nADA,\t2019\n).\tOnly\tthose\twith\tan\nabnormal\n\tresult\ton\tthe\t1-hour\tscreen\treceive\tthe\t3-hour\tdiagnostic\ttest.\tACOG\trecommends\tthat\tthe
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choice\tof\ta\tscreening\tcutpoint\tand\tthe\tchoice\tof\tdiagnostic\ttests\t(using\tthe\tCarpenter\tand\tCoustan\ncriteria\tif\ttesting\tserum\tor\tplasma,\tor\tthe\tNational\tDiabetes\tData\tGroup\tcriteria\tif\ttesting\tplasma),\nbe\tguided\tby\tlocal\tcommunity\tGDM\tprevalence\trates\t(\nACOG,\t2018c\n).\tAlthough\tcurrent\tpractice\nrequires\ttwo\tabnormal
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ACOG,\t2018c\n).\tAlthough\tcurrent\tpractice\nrequires\ttwo\tabnormal\n\tvalues\tfor\ta\tdiagnosis\tof\tGDM,\tfurther\tstudy\tis\trecommended\tto\tsee\tif\tthose\nwith\tonly\tone\televated\tvalue\talso\tbenefit\tfrom\ttreatment.\nAs\twith\tpreexisting\tdiabetes,\tthose\twomen\twith\tGDM\tshould\tbe\tfollowed\tcarefully\tduring
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pregnancy\tand\tmanaged\tby\ta\tdiabetes\tteam\tthat\tincludes\ta\tCDE.\tSee\t\nChapter\t29\n\tfor\tdiet\tand\nexercise\trecommendations,\tincluding\ttarget\tglucose\tvalues.\tMedications\tmay\tbe\tnecessary\n\tto\nmanage\tblood\tsugars.\tInsulin\tand\tsome\toral\thypoglycemic\tagents\t(e.g.,\tmetformin\tand\tglyburide)
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can\tbe\tused.\tLong-term\tuse\tof\tmetformin\tis\tassociated\twith\tdecreased\tvitamin\tB\n12\n\tlevels,\tbut\tits\tuse\nonly\tin\tlate\tpregnancy\thas\tnot\tbeen\tshown\tto\tbe\tproblematic\tfor\tmaintenance\tof\tnormal\tB\n12\n\tlevels\n(\nGatford\tet\tal,\t2013\n).\tThere\tis\tintriguing\tpreliminary\tevidence\tthat\tmyoinositol\tmay\tbe\thelpful\tin\npreventing
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preventing\n\tor\ttreating\tGDM\tand\tits\tuse\tappears\tto\tbe\tsafe\t(\nWerner\tand\tFroehlich,\t2016\n).\tHowever,\nits\tuse\tin\ttreating\tGDM\tis\tnot\tendorsed\tby\tthe\tCochrane\tReview\tbecause\tof\tthe\tlimited\tdata\navailable\t(\nBrown\tet\tal,\t2016\n).\tInositol\tdoes\tnot\tappear\tto\tlower\tthe\trisk\tof\tan\tLGA\tbaby\tand\tother
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clinically\tmeaningful\toutcomes\thave\tnot\tbeen\treported.\tOptimal\tdose,\tfrequency,\tand\ttiming\tof\nsupplementation\tare\tall\tcurrently\n\tunknown,\tas\tare\tthe\tlong-term\teffects.\tIts\tpreconceptual\tuse,\nalong\twith\tother\tmicronutrients\tand\tprobiotics,\tto\thelp\timprove\tinsulin\tsensitivity\tis\tcurrently\tbeing\nstudied\t(\nGodfrey\tet\tal,\t2017a\n).
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studied\t(\nGodfrey\tet\tal,\t2017a\n).\nWomen\twith\tGDM\tshould\tbe\tscreened\tfor\tpersistent\tdiabetes\tat\t4\tto\t12\tweeks\tpostpartum,\tusually\nwith\tfasting\tand\t2-hour\t(after\ta\t75g\tglucose\tload)\tblood\tsugars,\tand\tat\tleast\tevery\t3\tyears\tfor\ndiabetes\n\tor\tprediabetes,\tusing\tnonpregnancy\tdiagnostic\tcriteria\t(\nADA,\t2019\n;\tsee\t\nChapter\t29\n).\nEating\tdisorders
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ADA,\t2019\n;\tsee\t\nChapter\t29\n).\nEating\tdisorders\nThe\trates\tof\teating\tdisorders\tduring\tpregnancy\tare\t1%\tfor\tanorexia\tnervosa\tand\tslightly\tmore\tfor\nbulimia,\twith\tthe\tprevalence\tlikely\tunderestimated\t(\nCardwell,\t2013\n)\tbecause\tof\tvoluntary\nnondisclosure\tor\tbecause\tthe\tmedical\tpractitioner\tis\tnot\tassessing\tthe\trisk\t(\nLeddy\tet\tal,\t2009\n).\nAnorexia
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