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and\tbiotin,\t2000\t(website):\t\nhttps://www.gezondheidsraad.nl/sites/default/files/summary200012N_1.pdf\n;\tNetherlands\tNutrition\tCenter,\tSummary\tTable\t1a.\tDaily\trecommendations:\tRecommended\tDaily\tAllowances\t(RDAs)\tor\tAdequate\tIntakes\n(AIs),\t2014.\n7.\t\nSpain:\tGuías\ty\therramientas:\n\tingestas\tdietéticas\tde\treferencia\t(IDR)\tpara\tla\tpoblación\tEspañola,
|
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ingestas\tdietéticas\tde\treferencia\t(IDR)\tpara\tla\tpoblación\tEspañola,\t\nAct\tDiet\n\t14:196,\t2010,(website):\t\nhttps://www.ucm.es/data/cont/docs/458-2018-01-26-cap-3-ingestas-recomendadas-2018.pdf\n.
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] |
15\nNutrition\tin\tinfancy\nKelly\tN.\tMcKean,\tMS,\tRDN,\tCSP,\tCD,\tMari\tO.\tMazon,\tMS,\tRDN,\tCD\nKEY\tTERMS\nalpha-lactalbumin\narachidonic\tacid\t(ARA)\nbaby-led\tweaning\ncasein\ncasein\thydrolysate\ncatch-up\tgrowth\ncolostrum\ndocosahexaenoic\tacid\t(DHA)\nearly\tchildhood\tcaries\t(ECC)\nelectrolytically\treduced\tiron\ngrowth\tchannel\nlactoferrin\nlag-down\tgrowth
|
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] |
growth\tchannel\nlactoferrin\nlag-down\tgrowth\noligosaccharides\npalmar\tgrasp\npincer\tgrasp\nrenal\tsolute\tload\nsecretory\timmunoglobulin\tA\t(sIgA)\nwhey\tproteins\nDuring\tthe\tfirst\t2\tyears\tof\tlife,\twhich\tare\tcharacterized\tby\trapid\tphysical\tand\tsocial\tgrowth\tand\ndevelopment,\tmany\tchanges\toccur\tthat\taffect\tfeeding\tand\tnutrient\tintake.\tThe\tadequacy\tof\tinfants’
|
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nutrient\tintakes\taffects\ttheir\tinteraction\twith\ttheir\tenvironment.\tHealthy,\twell-nourished\tinfants\nhave\tthe\tenergy\n\tto\trespond\tto\tand\tlearn\tfrom\tthe\tstimuli\tin\ttheir\tenvironment\tand\tto\tinteract\twith\ntheir\tparents\tand\tcaregivers\tin\ta\tmanner\tthat\tencourages\tbonding\tand\tattachment.\nPhysiologic\tdevelopment
|
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] |
Physiologic\tdevelopment\nThe\tlength\tof\tgestation,\tthe\tmother’s\tprepregnancy\tweight,\tand\tthe\tmother’s\tweight\tgain\tduring\ngestation\tdetermine\tan\tinfant’s\tbirth\tweight.\tAfter\tbirth,\tthe\tgrowth\tof\tan\tinfant\tis\tinfluenced\tby\ngenetics\n\tand\tnourishment.\tMost\tinfants\twho\tare\tgenetically\tdetermined\tto\tbe\tlarger\treach\ttheir\ngrowth\tchannel
|
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] |
growth\tchannel\n,\ta\tcurve\tof\tweight\tand\tlength\tor\theight\tgain\tthroughout\tthe\tperiod\tof\tgrowth,\tat\nbetween\t3\tand\t6\tmonths\tof\tage.\tHowever,\tmany\tinfants\tborn\tat\tor\tbelow\tthe\ttenth\tpercentile\tfor\nlength\tmay\tnot\treach\ttheir\tgenetically\tappropriate\tgrowth\tchannel\tuntil\t1\tyear\tof\tage;\tthis\tis\tcalled\ncatch-up\tgrowth\n.
|
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catch-up\tgrowth\n.\n\tInfants\twho\tare\tlarger\tat\tbirth\tand\twho\tare\tgenetically\tdetermined\tto\tbe\tsmaller\ngrow\tat\ttheir\tfetal\trate\tfor\tseveral\tmonths\tand\toften\tdo\tnot\treach\ttheir\tgrowth\tchannel\tuntil\t13\nmonths\tof\tage.\tThis\tphenomenon\tduring\tthe\tfirst\tyear\tof\tlife\tis\tcalled\t\nlag-down\tgrowth\n.
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0.016578108072280884,
0.03651091828942299,
0.0822923555970192,
0.06635469198226929,
0.017768114805221558
] |
lag-down\tgrowth\n.\nGrowth\tin\tinfancy\tis\tmonitored\twith\tthe\troutine\tcollection\tand\tmonitoring\tof\tanthropometric\tdata,\nincluding\tweight,\tlength,\thead\n\tcircumference,\tand\tweight-for-length\tfor\tage.\tThese\tare\tplotted\ton\nthe\tappropriate\tWorld\tHealth\tOrganization\t(WHO)\tgrowth\tchart\tshown\tin\t\nAppendix\t3\n.\tThe\tWHO
|
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] |
Appendix\t3\n.\tThe\tWHO\ngrowth\tcharts\tare\tused\tfor\tthe\tfirst\t2\tyears\tof\tlife\tand\tconsist\tof\ta\tseries\tof\tpercentile\tcurves\tthat\nshow\tthe\tdistribution\tof\tbody\tmeasurements\tin\tinfants\tand\tchildren\tin\toptimal\tgrowth\tconditions.\nWhen\tthe\tanthropometric\tdata\tare\tplotted\n\ton\tthe\tgrowth\tcharts,\tthe\tpercentiles\trank\tthe\tinfant\tby
|
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on\tthe\tgrowth\tcharts,\tthe\tpercentiles\trank\tthe\tinfant\tby\nshowing\twhat\tpercentage\tof\tthe\treference\tpopulation\tthe\tinfant\twould\tequal\tor\texceed.\tFor\texample,\na\t7-month-old\tinfant\tgirl\twho\thas\ta\tweight-for-age\tat\tthe\t75th\tpercentile\tweighs\tthe\tsame\tor\tmore
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newborn\tperiod\tindicates\tneed\tfor\tfurther\tassessment\tregarding\tadequacy\tof\tfeeding.\tGrowth\nthereafter\tproceeds\tat\ta\trapid\tbut\tdecelerating\trate.\tInfants\n\tusually\tdouble\ttheir\tbirth\tweight\tby\t4\tto\n6\tmonths\tof\tage\tand\ttriple\tit\tby\tthe\tage\tof\t1\tyear.\tThe\tamount\tof\tweight\tgained\tby\tthe\tinfant\tduring
|
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the\tsecond\tyear\tapproximates\tthe\tbirth\tweight.\tInfants\tincrease\ttheir\tlength\tby\t50%\tduring\tthe\tfirst\nyear\tof\tlife\tand\tdouble\tit\tby\t4\tyears.\tTotal\tbody\tfat\tincreases\trapidly\tduring\tthe\tfirst\t9\tmonths,\tafter\nwhich\tthe\trate\tof\tfat\tgain\ttapers\toff\tthroughout\tthe\n\trest\tof\tchildhood.\tTotal\tbody\twater\tdecreases
|
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rest\tof\tchildhood.\tTotal\tbody\twater\tdecreases\nthroughout\tinfancy\tfrom\t70%\tat\tbirth\tto\t60%\tat\t1\tyear.\tThe\tdecrease\tis\talmost\tall\tin\textracellular\nwater,\twhich\tdeclines\tfrom\t42%\tat\tbirth\tto\t32%\tat\t1\tyear\tof\tage.\nThe\tstomach\tcapacity\tof\tinfants\tincreases\tfrom\ta\trange\tof\t10\tto\t20\tmL\tat\tbirth\tto\t200\tmL\tby\t1
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year,\tenabling\tinfants\tto\tconsume\tmore\tfood\tat\ta\tgiven\ttime\tand\tat\tless\tfrequent\tintervals\n\tas\tthey\ngrow\tolder.\tDuring\tthe\tfirst\tweeks\tof\tlife,\tgastric\tacidity\tdecreases\tand\tfor\tthe\tfirst\tfew\tmonths\nremains\tlower\tthan\tthat\tof\tolder\tinfants\tand\tadults.\tThe\trate\tof\temptying\tis\trelatively\tslow,
|
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] |
depending\ton\tthe\tsize\tand\tcomposition\tof\tthe\tmeal.\tBecause\tperistalsis\tand\tsphincter\tfunction\talong\nthe\tdigestive\ttract\tcontinue\tto\tmature\tduring\tinfancy,\tnewborns\toften\texperience\tregurgitation\n(\nSingendonk\tet\tal,\t2014\n).\tReducing\tthe\tvolume\tat\teach\tfeeding\tor\tkeeping\tthe\tinfant\tupright
|
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] |
).\tReducing\tthe\tvolume\tat\teach\tfeeding\tor\tkeeping\tthe\tinfant\tupright\nimmediately\tafter\ta\tfeeding\tcan\thelp\treduce\tthe\trisk\tof\tregurgitation.\nFat\tabsorption\tvaries\tin\tthe\tneonate.\tHuman\tmilk\tfat\tis\twell\tabsorbed,\tbut\tbutterfat\tis\tpoorly\nabsorbed,\twith\tfecal\texcretions\tof\t20%\tto\t48%.\tThe\tfat\tcombinations\tin\tcommercially\tprepared\tinfant
|
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] |
formula\tare\twell\tabsorbed.\tThe\tinfant’s\tlingual\tand\tgastric\tlipases\n\thydrolyze\tshort-\tand\tmedium-\nchain\tfatty\tacids\tin\tthe\tstomach.\tGastric\tlipase\talso\thydrolyzes\tlong-chain\tfatty\tacids\tand\tis\nimportant\tin\tinitiating\tthe\tdigestion\tof\ttriglycerides\tin\tthe\tstomach.\tMost\tlong-chain\ttriglycerides
|
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] |
pass\tunhydrolyzed\tinto\tthe\tsmall\tintestine,\twhere\tthey\tare\tbroken\tdown\tby\tpancreatic\tlipase.\tThe\nbile\tsalt–stimulated\tlipase\tpresent\tin\thuman\tmilk\tis\tstimulated\tby\tthe\tinfant’s\n\tbile\tsalts\tand\nhydrolyzes\tthe\ttriglycerides\tin\tthe\tsmall\tintestine\tinto\tfree\tfatty\tacids\tand\tglycerol.\tBile\tsalts,\twhich
|
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] |
are\teffective\temulsifiers\twhen\tcombined\twith\tmonoglycerides,\tfatty\tacids,\tand\tlecithin,\taid\tin\tthe\nintestinal\tdigestion\tof\tfat.\nThe\tactivities\tof\tthe\tenzymes\tresponsible\tfor\tthe\tdigestion\tof\tdisaccharides—maltase,\tisomaltase,\nand\tsucrase—reach\tadult\tlevels\tby\t28\tto\t32\tweeks’\n\tgestation.\tLactase\tactivity\t(responsible\tfor
|
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] |
gestation.\tLactase\tactivity\t(responsible\tfor\ndigesting\tthe\tdisaccharide\tin\tmilk)\treaches\tadult\tlevels\tby\tbirth.\tPancreatic\tamylase,\twhich\tdigests\nstarch,\tcontinues\tto\tremain\tlow\tduring\tthe\tfirst\t6\tmonths\tafter\tbirth.\tIf\tthe\tinfant\tconsumes\tstarch\nbefore\tthis\ttime,\tincreased\tactivity\tof\tsalivary\tamylase\tand\tdigestion\tin\tthe\tcolon\tusually
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] |
compensate.\nThe\tneonate\thas\tfunctional\tbut\tphysiologically\n\timmature\tkidneys\tthat\tincrease\tin\tsize\tand\nconcentrating\tcapacity\tin\tthe\tearly\tweeks\tof\tlife.\tThe\tkidneys\tdouble\tin\tweight\tby\t6\tmonths\tand\ntriple\tin\tweight\tby\t1\tyear\tof\tage.\tThe\tlast\trenal\ttubule\tis\testimated\tto\tform\tbetween\tthe\teighth\tfetal
|
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] |
month\tand\tthe\tend\tof\tthe\tfirst\tpostnatal\tmonth.\tThe\tglomerular\ttuft\tis\tcovered\tby\ta\tmuch\tthicker\nlayer\tof\tcells\tthroughout\tneonatal\tlife\tthan\tat\tany\tlater\n\ttime,\twhich\tmay\texplain\twhy\tthe\tglomerular\nfiltration\trate\tis\tlower\tduring\tthe\tfirst\t9\tmonths\tof\tlife\tthan\tit\tis\tin\tlater\tchildhood\tand\tadulthood.\tIn
|
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] |
the\tneonatal\tperiod\tthe\tability\tto\tform\tacid,\turine,\tand\tconcentrate\tsolutes\tis\toften\tlimited.\tThe\trenal\nconcentrating\tcapacity\tat\tbirth\tmay\tbe\tlimited\tto\tas\tlittle\tas\t700\tmOsm/L\tin\tsome\tinfants.\tOthers\nhave\tthe\tconcentrating\tcapacity\tof\tadults\t(1200\n\tto\t1400\tmOsm/L).\tBy\t6\tweeks,\tmost\tinfants\tcan
|
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] |
to\t1400\tmOsm/L).\tBy\t6\tweeks,\tmost\tinfants\tcan\nconcentrate\turine\tat\tadult\tlevels.\tRenal\tfunction\tin\ta\tnormal\tnewborn\tinfant\tis\trarely\ta\tconcern;\nhowever,\tdifficulties\tmay\tarise\tin\tinfants\twith\tdiarrhea\tor\tthose\twho\tare\tfed\tformula\tthat\tis\ttoo\nconcentrated.\nNutrient\trequirements
|
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] |
concentrated.\nNutrient\trequirements\nNutrient\tneeds\tof\tinfants\treflect\trates\tof\tgrowth,\tenergy\texpended\tin\tactivity,\tbasal\tmetabolic\tneeds,\nand\tthe\tinteraction\n\tof\tthe\tnutrients\tconsumed.\tBalance\tstudies\thave\tdefined\tminimum\tacceptable\nlevels\tof\tintakes\tfor\ta\tfew\tnutrients,\tbut\tfor\tmost\tnutrients\tthe\tsuggested\tintakes\thave\tbeen
|
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extrapolated\tfrom\tthe\tintakes\tof\tnormal,\tthriving\tinfants\tconsuming\thuman\tmilk.\tThe\tdietary\nreference\tintakes\t(DRIs)\tfor\tinfants\tare\tshown\tin\tthe\tinside\tcover\tof\tthis\tbook.\nEnergy\nFull-term\tinfants\twho\tare\tbreastfed\tto\tsatiety\n\tor\twho\tare\tfed\ta\tstandard\tinfant\tformula\tgenerally
|
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weight,\ttheir\tenergy\tand\tnutrient\tintake\tshould\tbe\tmonitored\tcarefully.\tIf\tthe\trate\tof\tgrowth\tin\nlength\tdecreases\tor\tceases,\tpotential\tmalnutrition,\tan\tundetected\tdisease,\tor\tboth\tshould\tbe\ninvestigated\tthoroughly.\n\tIf\tthe\tweight\tgain\tproceeds\tat\ta\tmuch\tmore\trapid\trate\tthan\tgrowth\tin
|
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0.04078759253025055,
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] |
If\tthe\tweight\tgain\tproceeds\tat\ta\tmuch\tmore\trapid\trate\tthan\tgrowth\tin\nlength,\tthe\tenergy\tconcentration\tof\tthe\tformula,\tthe\tquantity\tof\tformula\tconsumed,\tand\tthe\tamount\nand\ttype\tof\tsemisolid\tand\ttable\tfoods\toffered\tshould\tbe\tevaluated.\tThe\tactivity\tlevel\tof\tthe\tinfant\talso
|
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] |
should\tbe\tassessed.\tInfants\twho\tare\tat\tthe\thighest\tend\tof\tthe\tgrowth\tcharts\tfor\tweight-for-length,\tor\nwho\tgrow\trapidly\tin\n\tinfancy,\ttend\tto\tbe\tat\tgreater\trisk\tfor\tobesity\tlater\tin\tlife\t(\nDruet\tet\tal,\t2012\n).\nThe\tequations\tto\tcalculate\tthe\testimated\tenergy\trequirement\t(EER)\tfor\tinfants\t0\tto\t12\tmonths\tof\nage\tare\tin\t\nTable\t15.1
|
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-0.03894922509789467,
-0.043449271470308304,
-0.0844944640994072,
-0.015807796269655228,
-0.005189327988773584,
-0.029058212414383888,
-0.05393404886126518,
-0.0017382167279720306,
-0.10273104161024094,
0.0596885047852993,
-0.0822332352399826,
-0.02983280085027218,
0.0016029111575335264,
-0.048514317721128464,
0.030745096504688263,
0.030984731391072273,
-0.020435279235243797,
-0.10735134780406952,
-2.046056283491658e-33,
-0.07705222815275192,
0.04071090742945671,
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0.04668997973203659,
0.010449056513607502,
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0.021054502576589584,
0.060916829854249954,
0.09959642589092255,
0.0010233874199911952,
0.0818304792046547,
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0.011158108711242676,
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0.07639158517122269,
0.026641840115189552,
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0.017797179520130157,
0.09807702898979187,
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0.12239599972963333,
0.0035386180970817804,
0.09495767205953598,
0.06060492619872093,
0.07000695914030075,
0.056500211358070374,
-5.4097032631261754e-8,
-0.02363050915300846,
-0.0636155754327774,
0.020066935569047928,
0.04468805342912674,
0.030501607805490494,
0.008035743609070778,
0.034230031073093414,
0.022349322214722633,
-0.04589897394180298,
-0.01581679843366146,
0.09298374503850937,
0.08011633902788162,
-0.08614884316921234,
-0.02402249164879322,
0.04985802248120308,
-0.012653053738176823,
-0.011880883015692234,
0.1350899338722229,
-0.0671067163348198,
-0.07369262725114822,
-0.023167181760072708,
0.10682935267686844,
-0.028836695477366447,
-0.0035930161830037832,
-0.024618899449706078,
-0.013095900416374207,
-0.04669078439474106,
0.010047373361885548,
-0.019025836139917374,
0.035972535610198975,
0.07155336439609528,
-0.007554077077656984,
0.0009708674624562263,
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-0.06574799865484238,
0.03304643556475639,
-0.03386777639389038,
0.002555584767833352,
0.015915684401988983,
0.13730749487876892,
-0.01951555907726288,
-0.016259273514151573,
0.022889001294970512,
0.07835929095745087,
0.09265157580375671,
-0.1101163923740387,
-0.024528594687581062,
0.05282486602663994,
-0.009649249725043774,
-0.05685865134000778,
0.00229392247274518,
0.05509166792035103,
0.014417511411011219,
-0.01840546913444996,
-0.018405238166451454,
0.04074321314692497,
0.03834459185600281,
0.05262858048081398,
-0.03284427523612976,
0.0423969104886055,
0.06544218212366104,
0.05654224008321762,
0.03514564037322998,
-0.012442867271602154
] |
age\tare\tin\t\nTable\t15.1\n.\tThe\tEER\tincludes\tthe\ttotal\tenergy\texpenditure\tplus\tenergy\tneeded\tfor\tgrowth\nfor\thealthy\tinfants\twith\tnormal\tgrowth\t(see\t\nChapter\t2\n).
|
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0.11805111169815063,
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0.07173842936754227,
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0.08004020154476166,
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0.11175674945116043,
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0.034497540444135666,
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0.00950644165277481,
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0.04964956268668175,
0.01673327200114727,
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0.055666498839855194,
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-0.03182956948876381,
-0.0417456179857254,
0.03253154829144478,
0.008712347596883774,
-0.07861003279685974,
-0.02924000844359398,
0.021732771769165993,
-0.01575828716158867,
-0.025147676467895508,
0.031742390245199203,
0.11036965250968933,
0.005528995767235756,
0.008923716843128204,
-0.1028473749756813,
0.0368402823805809,
0.07877033203840256,
0.021080108359456062,
0.029673954471945763,
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0.0383840873837471,
0.05913522094488144,
0.05387350544333458,
0.01666882447898388
] |
Table\t15.1\nEquations\tfor\tCalculating\tEstimated\tEnergy\tRequirement\n\t(EER)\tfor\tInfants\nAge\nCalculation\n0-3\tmonths\n(89\t×\tWeight\tof\tinfant\t[kg]\t–\t100)\t+\t175\n4-6\tmonths\n(89\t×\tWeight\tof\tinfant\t[kg]\t–\t100)\t+\t56\n7-12\tmonths\n(89\t×\tWeight\tof\tinfant\t[kg]\t–\t100)\t+\t22\nFrom\tInstitute\tof\tMedicine:
|
[
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0.03308173641562462,
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0.02437468059360981,
0.05503125488758087,
0.13298602402210236,
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0.037959009408950806,
0.06891876459121704,
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0.04532026872038841,
0.008971938863396645,
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] |
(89\t×\tWeight\tof\tinfant\t[kg]\t–\t100)\t+\t22\nFrom\tInstitute\tof\tMedicine:\t\nDietary\treference\tintakes\tfor\tenergy,\tcarbohydrate,\tfiber,\tfat,\tfatty\tacids,\tcholesterol,\tprotein,\tand\tamino\tacids\n,\nWashington,\tDC,\t2002/2005,\tThe\tNational\tAcademies\n\tPress.\nProtein\nProtein\tis\tneeded\tfor\ttissue\treplacement,\tdeposition\tof\tlean\tbody\tmass,\tand\tgrowth.\tProtein
|
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0.07453033328056335,
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0.07473287731409073,
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0.011221547611057758,
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0.01853310316801071,
0.027970880270004272,
0.006970875430852175,
0.042586009949445724,
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0.053230028599500656,
0.0016268508043140173,
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0.14515900611877441,
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0.08036381751298904,
0.06943896412849426,
-0.1256897747516632,
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0.14079459011554718,
0.028164474293589592,
-0.09585048258304596,
0.017807701602578163,
0.08987565338611603,
-0.052651096135377884,
0.0005321197095327079,
-0.09468472003936768,
0.030188612639904022,
0.04439937323331833,
0.017552150413393974,
0.010397585108876228,
0.018120896071195602,
0.05917913094162941,
0.06498384475708008,
0.1089579164981842,
0.00663995835930109
] |
requirements\tduring\tthe\trapid\tgrowth\tof\tinfancy\tare\thigher\tper\tkilogram\tof\tweight\tthan\tthose\tfor\nolder\tchildren\tor\tadults\t(\nTable\t15.2\n).\tRecommendations\tfor\tprotein\tintake\tare\tbased\ton\tthe\ncomposition\tof\thuman\tmilk,\tand\tit\tis\tassumed\tthat\tthe\tefficiency\tof\thuman\tmilk\tuse\tis\t100%.\nTable\t15.2\nProtein\tDietary\tReference\tIntakes\t(DRIs)\tfor\tInfants\nAge
|
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0.00007777583959978074,
0.0316614992916584,
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0.05660315230488777,
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0.057383548468351364,
0.0695444867014885,
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0.05650670453906059,
0.02120337449014187,
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0.12463254481554031,
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0.08473560214042664,
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0.06626676023006439,
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0.02215617150068283,
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0.0039286366663873196,
0.04441746324300766,
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0.001652945182286203,
0.09550873190164566,
0.03789255768060684,
0.055327270179986954,
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0.08896488696336746,
0.11448172479867935,
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0.09584241360425949,
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0.045382723212242126,
0.011631179600954056,
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0.03841756284236908,
0.07056387513875961,
0.035765912383794785,
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0.004788514226675034,
0.09545273333787918,
0.07673241198062897,
0.08056040853261948,
0.019376475363969803
] |
Table\t15.2\nProtein\tDietary\tReference\tIntakes\t(DRIs)\tfor\tInfants\nAge\nGrams/Day\nGrams/Kilogram/Day\n0-6\tmonths\n9.1\n1.52\n6-12\tmonths\n11\n1.2\nFrom\tInstitute\tof\tMedicine:\t\nDietary\treference\tintakes\tfor\tenergy,\tcarbohydrate,\tfiber,\tfat,\tfatty\tacids,\tcholesterol,\tprotein,\tand\tamino\tacids\n,\nWashington,\tDC,\t2002/2005,\tThe\tNational\tAcademies\tPress.
|
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0.01791614294052124,
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0.017604930326342583,
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0.07722657173871994,
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0.14707349240779877,
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0.052556563168764114,
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0.040212832391262054,
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0.06041468307375908,
0.03622753545641899,
0.08436165004968643,
0.050546761602163315,
0.008215143345296383,
0.014895087108016014,
0.14859303832054138,
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0.003393408842384815,
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0.04252287372946739,
0.019037585705518723,
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] |
,\nWashington,\tDC,\t2002/2005,\tThe\tNational\tAcademies\tPress.\nInfants\trequire\ta\tlarger\tpercentage\tof\ttotal\n\tamino\tacids\tas\tessential\tamino\tacids\tthan\tdo\tadults.\nHistidine\tseems\tto\tbe\tan\tessential\tamino\tacid\tfor\tinfants,\tbut\tnot\tfor\tadults,\tand\ttyrosine,\tcystine,\nand\ttaurine\tmay\tbe\tessential\tfor\tpremature\tinfants\t(\nPencharz\tand\tBall,\t2006\n;\tsee
|
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] |
Pencharz\tand\tBall,\t2006\n;\tsee\t\nChapter\t41\n).\nHuman\tmilk\tor\tinfant\tformula\tprovides\tthe\tmajor\tportion\tof\tprotein\tduring\tthe\tfirst\tyear\tof\tlife.\nThe\tamount\tof\tprotein\tin\thuman\tmilk\tis\tadequate\n\tfor\tthe\tfirst\t6\tmonths\tof\tlife,\teven\tthough\tthe\namount\tof\tprotein\tin\thuman\tmilk\tis\tconsiderably\tless\tthan\tin\tinfant\tformula.\tFrom\t6\tmonths\tof\tage
|
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] |
the\tdiet\tshould\tbe\tsupplemented\twith\tadditional\tsources\tof\thigh-quality\tprotein,\tsuch\tas\tyogurt,\nstrained\tmeats,\tpureed\tlegumes,\tmashed\tegg\tyolk,\tpureed\tfish\twith\tlow\tmercury\tcontent\t(i.e.,\nsalmon,\tchunk\tlight\ttuna,\tpollock,\tcod,\tand\tperch),\tor\tcereal\tmixed\n\twith\tformula\tor\thuman\tmilk.\tA
|
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] |
with\tformula\tor\thuman\tmilk.\tA\ncomplete\tlist\tof\tlow\tmercury\tseafood\tcan\tbe\tfound\ton\tthe\tFood\tand\tDrug\tAdministration\t(FDA)\nwebsite\tunder\t“Eating\tfish:\tWhat\tpregnant\twomen\tand\tparents\tneed\tto\tknow.”\nInfants\tmay\tnot\treceive\tadequate\tprotein\tif\ttheir\tformula\tis\texcessively\tdiluted\tfor\ta\tprolonged
|
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] |
period,\tor\tif\tthey\thave\tmultiple\tfood\tallergies\tand\tare\tplaced\ton\ta\trestricted\tdiet\twithout\tappropriate\nmedical\tor\tnutritional\tsupervision\t(see\t\nChapter\t25\n).\nLipids\nLipids\tprovide\ta\tlarge\tproportion\tof\tinfants’\tenergy\tintakes\tin\torder\tto\tmeet\tthe\tenergy\tdemands\tfor
|
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] |
and\tthe\taverage\tfat\tintakes\tfrom\tbreastmilk\tand\tcomplementary\tfoods\nfor\tinfants\t7\tto\t12\tmonths.\tSignificantly\tlower\tfat\tintakes\t(e.g.,\twith\tskim-milk\tfeedings)\tmay\tresult\nin\tan\tinadequate\ttotal\tenergy\tintake.\tAn\tinfant\tmay\ttry\tto\tcorrect\tthe\tenergy\tdeficit\tby\tincreasing
|
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] |
the\tvolume\tof\tmilk\tingested\tbut\tusually\tcannot\tmake\tup\tthe\tentire\tdeficit\tthis\tway.\nHuman\tmilk\tcontains\tthe\tessential\tfatty\n\tacids\tlinoleic\tacid\tand\talpha-linolenic\tacid,\tas\twell\tas\tthe\nlonger-chain\tderivatives\t\narachidonic\tacid\t(ARA)\n\t(C20:4ω-6)\tand\t\ndocosahexaenoic\tacid\t(DHA)
|
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] |
arachidonic\tacid\t(ARA)\n\t(C20:4ω-6)\tand\t\ndocosahexaenoic\tacid\t(DHA)\n(C22:6ω-3).\tWhile\tARA\tcontent\tof\thuman\tmilk\tis\tmostly\tconsistent\tand\tunaffected\tby\tthe\tmother’s\ndiet,\tDHA\tcontent\tdoes\treflect\tthe\tmother’s\tintakes\tand\tis\tfound\tin\ta\twide\trange\tof\tconcentrations\tin\nhuman\tmilk\t(\nCarlson\tand\tColombo,\t2016\n).\tSee\t\nChapter\t14\n\t\nFocus\tOn
|
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0.028004799038171768
] |
human\tmilk\t(\nCarlson\tand\tColombo,\t2016\n).\tSee\t\nChapter\t14\n\t\nFocus\tOn\n:\tOmega-3\tFatty\tAcids\tin\nPregnancy\tand\tLactation.\tInfant\tformulas\tare\tsupplemented\twith\tlinoleic\tacid\tand\talpha-linolenic\nacid,\tfrom\twhich\tARA\tand\tDHA\tare\tderived.\tExcept\tfor\ta\tfew\tspecialty\tproducts,\tstandard\tformulas
|
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] |
for\tterm\tinfants\tin\tthe\tUnited\tStates\tnow\talso\tare\tsupplemented\twith\tARA\tand\tDHA,\talthough\tthere\nare\tno\tregulatory\trequirements\tfor\ttheir\tinclusion.\nLinoleic\tacid\tis\tessential\n\tfor\tgrowth\tand\tdermal\tintegrity.\tThe\tadequate\tintake\tfor\tinfants\thas\tbeen
|
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set\tbased\ton\tthe\taverage\tlinoleic\tacid\tintake\tfrom\tbreastmilk,\tor\t4.4\tg/day\tfor\tinfants\tyounger\tthan\t6\nmonths\tof\tage\tand\tbased\ton\tthe\taverage\tintake\tfrom\tbreastmilk\tand\tcomplementary\tfoods,\tor\t4.6\ng/day\tfor\tinfants\t7\tmonths\tto\t1\tyear\tof\tage.\tThe\thuman\tmilk\tcontent\tof\tlinoleic\tacid\tvaries\tbased\ton\nthe\tmother’s\tdiet;\tits
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the\tmother’s\tdiet;\tits\n\tcaloric\tcontribution\tcan\trange\tfrom\tapproximately\t6%\tto\t10%\tof\tbreastmilk’s\nenergy\tcontent.\tThe\tInfant\tFormula\tAct\tof\t1980\trequires\tthat\tat\tleast\t2.7%\tof\tinfant\tformula’s\ttotal\nenergy\tbe\tfrom\tlinoleic\tacid.\tSafflower,\tcorn,\tand\tsoybean\toil\tare\tgood\tsources\tof\tlinoleic\tacid.\tThe
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current\trecommendation\tfor\talpha-linolenic\tacid\tis\t0.5\tg/day\tduring\tthe\tfirst\tyear\tof\tlife.\tThis\tis\nbased\ton\tthe\taverage\n\tintakes\tfrom\tbreastmilk\tfor\tinfants\t0\tto\t6\tmonths\tand\taverage\tintakes\tfrom\nbreastmilk\tand\tcomplementary\tfoods\tfor\tinfants\t7\tto\t12\tmonths.\tFlaxseed,\tchia\tseed,\tcanola\toil,\tand
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soybean\toil\tare\tgood\tsources\tof\talpha-linolenic\tacid.\nThe\tconcentration\tof\tDHA\tin\thuman\tmilk\tvaries,\tdepending\ton\tthe\tamount\tof\tDHA\tin\tthe\tmother’s
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diet.\tDHA\tand\tARA\tare\tthe\tmajor\tomega-3\tand\tomega-6\tlong-chain\tpolyunsaturated\n\tfatty\tacids\n(LCPUFAs)\tof\tneural\ttissues,\tand\tDHA\tis\tthe\tmajor\tfatty\tacid\tof\tthe\tphotoreceptor\tmembranes\tof\tthe\nretina.\tStudies\tlooking\tat\tvisual,\tneurodevelopmental,\tor\tgrowth\toutcomes\tin\tformula-fed\tterm
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infants\ton\tDHA-\tor\tARA-supplemented\tformula\thave\tshown\tmixed\tresults\t(\nJasani\tet\tal,\t2017\n).\tStudies\nare\tfinding\tthat\tthe\tratio\tof\tDHA\tto\tARA\tadded\tto\tformula\tmay\tbe\tcritical\t(\nCarlson\tand\tColombo,\n2016\n).\tThe\tAmerican\tAcademy\tof\tPediatrics\t(AAP)\thas\tnot\ttaken\tan\tofficial\tstand\ton\tthe\taddition\tof\nLCPUFAs\tto\tinfant\tformula.\nCarbohydrates
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] |
LCPUFAs\tto\tinfant\tformula.\nCarbohydrates\nCarbohydrates\tshould\tsupply\t30%\tto\t60%\tof\tthe\tenergy\tintake\tduring\tinfancy.\tApproximately\t40%\tof\nthe\tenergy\tin\thuman\tmilk\tand\t40%\tto\t50%\tof\tthe\tenergy\tin\tinfant\tformulas\tis\tderived\tfrom\tlactose\tor\nother\tcarbohydrates.\tAlthough\trare,\tsome\tinfants\tcannot\ttolerate\n\tlactose\tand\trequire\ta\tmodified
|
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] |
lactose\tand\trequire\ta\tmodified\nformula\tin\ttheir\tdiet\t(see\t\nChapters\t27\n\tand\t\n42\n).\nThe\tadequate\tintake\tfor\tbirth\tto\t6\tmonths\tis\t60\tg/day.\tThis\tis\tbased\ton\tthe\taverage\tcarbohydrate\nintake\tfrom\thuman\tmilk.\tThe\tadequate\tintake\tfor\t7\tmonths\tto\t12\tmonths\tis\t95\tg/day.\tThis\tis\tbased\ton
|
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] |
the\taverage\tcarbohydrate\tintake\tfrom\thuman\tmilk\tand\tcomplementary\tfoods.\tGrains\t(cereal,\tpasta,\nrice),\tstarchy\tvegetables\n\t(peas,\tcorn,\tpotatoes),\tand\tsugar\tfrom\tfruits\tprovide\tnatural\tsources\tof\ncarbohydrates.\nBotulism\tin\tinfancy\tis\tcaused\tby\tthe\tingestion\tof\t\nClostridium\tbotulinum\n\tspores,\twhich\tgerminate
|
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] |
Clostridium\tbotulinum\n\tspores,\twhich\tgerminate\nand\tproduce\ttoxins\tin\tthe\tbowel\tlumen.\tInfant\tbotulism\thas\tbeen\tassociated\twith\teating\thoney\tthat\ncontains\tthe\tbacterial\tspores.\tLight\tand\tdark\tcorn\tsyrups\talso\thave\tbeen\treported\tto\tcontain\tthe\nspores,\talthough\n\tcases\tof\tinfant\tbotulism\thave\tnot\tbeen\tlinked\tto\tcorn\tsyrup.\tThe\tspores\tare
|
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extremely\tresistant\tto\theat\ttreatment\tand\tare\tnot\tdestroyed\tby\tcurrent\tmethods\tof\tprocessing.\tThus\nhoney\tand\tcorn\tsyrup\tshould\tnot\tbe\tfed\tto\tinfants\tyounger\tthan\t1\tyear\tof\tage\tbecause\tthey\thave\tnot\nyet\tdeveloped\tthe\timmunity\trequired\tto\tresist\tbotulism\tspore\tdevelopment.\nWater\nThe\twater\trequirement\tfor\tinfants\tis\tdetermined
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] |
Water\nThe\twater\trequirement\tfor\tinfants\tis\tdetermined\n\tby\tthe\tamount\tlost\tfrom\tthe\tskin\tand\tlungs\tand\tin\nthe\tfeces\tand\turine,\tin\taddition\tto\ta\tsmall\tamount\tneeded\tfor\tgrowth.\tThe\trecommended\ttotal\twater\nintake\tfor\tinfants,\tbased\ton\tthe\tDRIs,\tis\t0.7\tL/day\tfor\tinfants\tup\tto\t6\tmonths\tand\t0.8\tL/day\tfor\tinfants
|
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] |
6\tto\t12\tmonths\tof\tage.\tNote\tthat\ttotal\twater\tincludes\tall\twater\tcontained\tin\tfood,\tbeverages,\tand\ndrinking\twater.\tFluid\trecommendations\tper\n\tkilogram\tof\tbody\tweight\tare\tshown\tin\t\nTable\t15.3\n.\nTable\t15.3\nMaintenance\tFluid\tRequirements\tof\tInfants\tand\tChildren\t(Holliday-Segar\tMethod)\nBody\tWeight\nFluid\tRequirement\n0-10\tkg\n100\tmL/kg\n11-20\tkg
|
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] |
Body\tWeight\nFluid\tRequirement\n0-10\tkg\n100\tmL/kg\n11-20\tkg\n1000\tmL\t+\t50\tmL/kg\tfor\teach\tkg\tabove\t10\tkg\n>20\tkg\n1500\tmL\t+\t20\tmL/kg\tfor\teach\tkg\tabove\t20\tkg\nFrom\tHolliday\tMA,\tSegar\tWE.\tThe\tmaintenance\tneed\tfor\twater\tin\tparenteral\tfluid\ttherapy.\t\nPediatrics\n\t19:823-832,\t1957.
|
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0.07577796280384064,
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] |
Pediatrics\n\t19:823-832,\t1957.\nBecause\tthe\trenal\tconcentrating\tcapacity\tof\tyoung\tinfants\tmay\tbe\tless\tthan\tthat\tof\tolder\tchildren\nand\tadults,\tthey\tmay\tbe\tvulnerable\tto\tdeveloping\ta\twater\timbalance.\tUnder\tordinary\tconditions,\nhuman\tmilk\tand\tformula\tthat\tis\tproperly\tprepared\tsupply\tadequate\tamounts\tof\twater.\tHowever,
|
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] |
when\tformula\tis\tboiled,\tthe\twater\tevaporates\tand\tthe\tsolutes\tbecome\tconcentrated;\n\ttherefore,\tboiled\nmilk\tor\tformula\tis\tinappropriate\tfor\tinfants.\tIn\tvery\thot\tand\thumid\tenvironments,\tinfants\tmay\trequire\nadditional\twater.\tWhen\tlosses\tof\twater\tare\thigh\t(e.g.,\tvomiting\tand\tdiarrhea),\tinfants\tshould\tbe
|
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monitored\tcarefully\tfor\tfluid\tand\telectrolyte\timbalances.\nWater\tdeficits\tresult\tin\thypernatremic\tdehydration\tand\tits\tassociated\tneurologic\tconsequences\n(e.g.,\tseizures,\tvascular\n\tdamage).\tHypernatremic\tdehydration\thas\tbeen\treported\tin\tbreastfed\tinfants\nwho\tlose\tgreater\tthan\t10%\tof\ttheir\tbirth\tweight\tin\tthe\tfirst\tfew\tdays\tof\tlife\t(
|
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] |
Panagoda\tet\tal,\t2015\n).\nBecause\tof\tthe\tpotential\tfor\thypernatremic\tdehydration,\tcareful\tmonitoring\tof\tvolume\tof\tintake,\tdaily\nweights,\tand\thydration\tstatus\t(e.g.,\tnumber\tof\twet\tdiapers)\tin\tall\tnewborns\tis\twarranted.\nWater\tintoxication\tresults\n\tin\thyponatremia,\trestlessness,\tnausea,\tvomiting,\tdiarrhea,\tand\tpolyuria
|
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] |
or\toliguria;\tseizures\talso\tcan\tresult.\tThis\tcondition\tmay\toccur\twhen\twater\tis\tprovided\tas\ta\nreplacement\tfor\tmilk,\tthe\tformula\tis\texcessively\tdiluted,\tor\tbottled\twater\tis\tused\tinstead\tof\tan\nelectrolyte\tsolution\tin\tthe\ttreatment\tof\tdiarrhea.\nMinerals\nCalcium\nBreastfed\tinfants\tretain\tapproximately\ttwo\tthirds\tof\ttheir\tcalcium\n\tintake.\tThe\trecommended
|
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] |
intake.\tThe\trecommended\nadequate\tintake\t(AI),\tthe\tmean\tintake,\tis\tbased\ton\tcalcium\tintakes\tin\thealthy\tbreastfed\tinfants.\tThe\nAI\tfor\tinfants\t0\tto\t6\tmonths\tof\tage\tis\t200\tmg/day;\tthe\tAI\tfor\tinfants\t6\tto\t12\tmonths\tof\tage\tis\t260\nmg/day;\tformulas\tcontain\tmore\tcalcium\tper\tvolume\tthan\thuman\tmilk\tto\tassure\tsimilar\tlevels\tof\ncalcium\tabsorption\t(see
|
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] |
calcium\tabsorption\t(see\t\nAppendix\t39\n).\tDuring\tthe\tfirst\tyear\tof\tlife,\thuman\tmilk\n\tor\tinfant\tformula\tis\nthe\tmajor\tsource\tof\tcalcium.\tCow’s\tmilk\tor\tmilk\talternatives\tare\tnot\tappropriate\tsubstitutes.\nCalcium-fortified\tcereal,\tyogurt,\ttofu,\tand\tcheese\tare\tgood\tsources\tof\tcalcium.\nFluoride
|
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] |
The\timportance\tof\tfluoride\tin\tpreventing\tdental\tcaries\thas\tbeen\twell\tdocumented.\tHowever,\nexcessive\tfluoride\tmay\tcause\tdental\tfluorosis,\tranging\tfrom\tfine\twhite\tlines\tto\tentirely\tchalky\tteeth\n(see\t\nChapter\t24\n).\tTo\tprevent\tfluorosis,\tthe\ttolerable\tupper\tintake\tlevel\tfor\tfluoride\thas\tbeen\tset\tat
|
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] |
0.7\tmg/day\tfor\tinfants\tup\tto\t6\tmonths\tand\t0.9\tmg/day\tfor\tinfants\t6\tto\t12\tmonths\tof\tage.\tFluoride\nconcentration\tof\t0.7\tppm\t(0.7\tmg/L)\tin\tdrinking\twater\thas\tbeen\tproposed\tas\tbeing\toptimal\tfor\tsafety\nand\tcaries\tprevention\t(\nAcademy\tof\tNutrition\tand\tDietetics\t[AND],\t2012\n).\tFluoride\tcontent\tof\twater
|
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] |
).\tFluoride\tcontent\tof\twater\nsupplies\tcan\tbe\tobtained\tthrough\tlocal\tpublic\thealth\tdepartments\tor\twater\tutilities.\tFluoride\ncontaining\ttoothpaste\tshould\tbe\tused\tsparingly—just\ta\tsmear\ton\ta\ttoothbrush\t(\nAmerican\tAcademy\tof\nPediatric\tDentistry\t[AAPD],\t2014\n).
|
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American\tAcademy\tof\nPediatric\tDentistry\t[AAPD],\t2014\n).\nHuman\tmilk\tis\tvery\tlow\tin\tfluoride.\tInfants\twho\texclusively\tconsume\tinfant\tformula\treconstituted\nwith\tfluoridated\twater\tmay\tbe\tat\tincreased\trisk\tof\tdeveloping\tmild\tfluorosis\n\t(\nCenters\tfor\tDisease\nControl\tand\tPrevention\t[CDC],\t2015
|
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0.07035932689905167,
0.026316063478589058,
0.13530661165714264,
0.05140041187405586
] |
(\nCenters\tfor\tDisease\nControl\tand\tPrevention\t[CDC],\t2015\n).\tUsing\twater\tthat\tis\tfree\tof\tor\tlow\tin\tfluoride,\twhich\tare\twaters\nlabeled\t“purified,”\t“demineralized,”\t“deionized,”\t“distilled,”\tor\t“produced\tthrough\treverse-osmosis,”\nmay\tdecrease\tthis\trisk.\tOther\tdietary\tsources\tof\tfluoride\tduring\tinfancy\tinclude\tcommercially
|
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] |
prepared\tinfant\tcereals\tand\twet\tpack\tcereals\tprocessed\twith\tfluoridated\twater.\n\tFluoride\nsupplementation\tis\tnot\trecommended\tfor\tinfants\tyounger\tthan\t6\tmonths\tof\tage,\tand\tafter\t6\tmonths\nof\tage\tis\trecommended\tonly\tif\tan\tinfant\tis\tat\thigh\trisk\tof\tdeveloping\tdental\tcaries\tand\tdrinks\ninsufficiently\tfluoridated\twater\t(\nAND,\t2012
|
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] |
insufficiently\tfluoridated\twater\t(\nAND,\t2012\n).\tAfter\ttooth\teruption\tit\tis\trecommended\tthat\tfluoridated\nwater\tbe\toffered\tseveral\ttimes\tper\tday\tto\tbreastfed\tinfants,\tthose\twho\treceive\tcow’s\tmilk,\tand\n\tthose\nfed\tformulas\tmade\twith\twater\tthat\tcontain\tless\tthan\t0.3\tmg\tof\tfluoride/L\t(\nAAP,\t2014b\n).\nIron
|
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] |
AAP,\t2014b\n).\nIron\nFull-term\tinfants\tare\tconsidered\tto\thave\tadequate\tstores\tof\tiron\tfor\tgrowth\tup\tto\ta\tdoubling\tof\ttheir\nbirth\tweight.\tThis\toccurs\tat\tapproximately\t4\tmonths\tof\tage\tin\tfull-term\tinfants\tand\tmuch\tearlier\tin\nprematurely\tborn\tinfants.\tRecommended\tintakes\tof\tiron\tincrease\taccording\tto\tage,\tgrowth\trate,\n\tand
|
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] |
and\niron\tstores.\tAt\t4\tto\t6\tmonths\tof\tage,\tinfants\twho\tare\tfed\tonly\thuman\tmilk\tare\tat\trisk\tfor\tdeveloping\ta\nnegative\tiron\tbalance\tand\tmay\tdeplete\ttheir\treserves\tby\t6\tto\t9\tmonths.\tIron\tin\thuman\tmilk\tis\thighly\nbioavailable;\thowever,\tbreastfed\tinfants\tshould\treceive\tan\tadditional\tsource\tof\tiron\tby\t4\tto\t6\tmonths\nof\tage\t(\nAAP,\t2012
|
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of\tage\t(\nAAP,\t2012\n).\tFor\tbreastfed\tterm\tinfants,\tthe\tAAP\trecommends\tiron\tsupplementation\n\tof\t1\nmg/kg/day\tstarting\tat\t4\tmonths\tof\tage\tand\tcontinuing\tuntil\tappropriate\tcomplementary\tfoods\thave\nbeen\tintroduced\t(\nAAP,\t2014b\n).\tComplementary\tfoods\thigh\tin\tiron\tinclude\tstrained\tmeats\tand\tiron-
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).\tComplementary\tfoods\thigh\tin\tiron\tinclude\tstrained\tmeats\tand\tiron-\nfortified\tinfant\tcereals.\tIn\taddition,\tby\t6\tmonths\tof\tage\toffering\tone\tserving\tof\tvitamin\tC-rich\tfoods\nper\tday\tenhances\tiron\tabsorption\tfrom\tnonheme\tsources\tsuch\tas\ttofu,\tbeans,\tpeas,\tlentils,\tand\teggs.
|
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Formula-fed\tinfants\treceive\tadequate\tiron\tfrom\tformula.\tCow’s\tmilk\tis\ta\tpoor\tsource\tof\tiron\tand\nshould\tnot\tbe\tgiven\tbefore\t12\tmonths\tof\tage.\nIron\tdeficiency\tand\tiron\tdeficiency\tanemia\tare\tcommon\thealth\tconcerns\tfor\tthe\tolder\tinfant.\nBetween\t6\tand\t24\tmonths\tof\tage,\tbecause\tof\trapid\tgrowth,\tiron\trequirements\tper\tkilogram\tof\tbody
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intake\tof\tcow’s\tmilk,\tlow\tsocioeconomic\tstatus,\tand\timmigrant\tstatus.\nMonitoring\tiron\tstatus\tis\timportant\tbecause\tof\tthe\tlong-term\tcognitive\teffects\tof\tiron\tdeficiency\tin\ninfancy.\tThere\tis\tconsistent\tassociation\tbetween\tiron\tdeficiency\tanemia\tin\tinfancy\tand\tlong-lasting\npoor\tcognition,\tdevelopmental\tdeficits,\tand\tbehavioral\tperformance\t(
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] |
poor\tcognition,\tdevelopmental\tdeficits,\tand\tbehavioral\tperformance\t(\nDomellöf\tet\tal,\t2014\n).\tThus\tit\tis\nimportant\tthat\tthis\tdietary\tadvice\treaches\thigh-risk\tgroups\tto\tprevent\tthese\tsignificant\tlong-term\neffects\t(see\t\nAppendix\t42\n\tand\t\nChapter\t31\n).\nZinc
|
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] |
effects\t(see\t\nAppendix\t42\n\tand\t\nChapter\t31\n).\nZinc\nZinc\tis\tcritical\tfor\tgrowth\tand\tdevelopment.\tThe\tAI\tis\t2.0\tmg\tfor\tinfants\t0\tto\t12\tmonths.\tDuring\tthe\nfirst\t6\tmonths\tof\tlife,\thuman\tmilk\tor\tinfant\n\tformula\tprovides\tadequate\tzinc.\tAlthough\tzinc\tis\tbetter\nabsorbed\tfrom\thuman\tmilk\tthan\tfrom\tinfant\tformula,\tthe\tzinc\tcontent\tof\thuman\tmilk\tdecreases
|
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] |
during\tthe\tfirst\t6\tmonths.\tA\tdietary\tsource\tof\tzinc\tbecomes\tnecessary\tfor\tbreastfed\tinfants\tat\tthis\ntime.\tGood\tsources\tof\tzinc\twith\thigh\tbioavailability\tinclude\tred\tmeat,\teggs,\tyogurt,\tand\tcheese.\tThe\npresence\tof\tphytic\tacid\tmakes\tplant\tsources\tof\tzinc\n\t(grains,\tlegumes,\tnut\tproducts)\tless\tbioavailable.
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] |
(grains,\tlegumes,\tnut\tproducts)\tless\tbioavailable.\nInfants\twho\tare\tzinc\tdeficient\tcan\texhibit\tgrowth\timpairment\t(\nTerrin\tet\tal,\t2015\n;\tsee\t\nAppendix\t47\n).\nVitamins\nVitamin\tB\n12\nMilk\tfrom\tlactating\tmothers\twho\tfollow\ta\tstrict\tvegan\tdiet\tmay\tbe\tdeficient\tin\tvitamin\tB\n12\n,\tespecially
|
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] |
12\n,\tespecially\nif\tthe\tmother\tfollowed\tthe\tregimen\tfor\ta\tlong\ttime\tbefore\tand\tduring\ther\tpregnancy.\tVitamin\tB\n12\ndeficiency\thas\talso\n\tbeen\tdiagnosed\tin\tinfants\tbreastfed\tby\tmothers\twith\tpernicious\tanemia\n(\nRoumeliotis\tet\tal,\t2012\n;\tsee\t\nChapter\t32\n).\tDuring\tinfancy,\tsigns\tof\tvitamin\tB\n12\n\tdeficiency\tinclude
|
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] |
).\tDuring\tinfancy,\tsigns\tof\tvitamin\tB\n12\n\tdeficiency\tinclude\ninadequate\tgrowth,\treflux\tor\tfeeding\tdifficulties,\thypotonia,\tdevelopmental\tregression,\tand\nmovement\tdisorders\t(\nFadilah\tet\tal,\t2017\n;\tsee\t\nAppendix\t31\n).\tGood\tfood\tsources\tof\tvitamin\tB\n12\n\tinclude\nanimal\tproducts,\tincluding\tfish,\tmeat,\n\tpoultry,\teggs,\tmilk,\tand\tmilk\tproducts.\tVitamin\tB
|
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0.011195654049515724,
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0.0683855339884758,
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0.09041125327348709,
0.009342127479612827,
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0.08290023356676102,
0.029931794852018356,
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0.02921927534043789,
0.05289545655250549,
0.019335774704813957,
0.015330582857131958,
0.008118784986436367,
0.039029330015182495,
0.09415882080793381,
0.08297993987798691,
0.011330188252031803
] |
poultry,\teggs,\tmilk,\tand\tmilk\tproducts.\tVitamin\tB\n12\n\tis\tgenerally\nnot\tpresent\tin\tplant\tfoods,\tbut\tsome\tfoods\tare\tfortified\twith\tvitamin\tB\n12\n,\tsuch\tas\tbreakfast\tcereals,\nmeat\tsubstitutes,\tnondairy\tmilks,\tand\tnutritional\tyeast\tproducts.\nVitamin\tD\nThe\tvitamin\tD\tcontent\tof\tbreastmilk\tis\tcorrelated\tto\tthe\tvitamin\tD\tstatus\tof\tthe\tmother.\tStudies\thave
|
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] |
shown\tthat\thigh\tmaternal\tintakes\tof\tvitamin\tD,\n\tsupplemented\t2000\tIU\tto\t6400\tIU\tper\tday,\twere\nassociated\twith\thigher\tbreastmilk\tvitamin\tD\tconcentrations.\tHowever,\tinfants\tof\tmothers\nsupplemented\twith\t2000\tIU\tper\tday\tor\tmore\thave\tsimilar\tserum\tconcentrations\tas\tinfants\treceiving
|
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a\tvitamin\tD\tsupplement\tof\t400\tIU\tper\tday\t(\nMunns\tet\tal,\t2016\n).\tThe\tcurrent\trecommended\tdietary\nallowance\t(RDA)\tfor\tvitamin\tD\tfor\tlactating\tmothers\tis\t600\tIU\tper\tday,\n\tand\tthe\ttolerable\tupper\tlimit\nis\t4000\tIU\tper\tday.\tCoupled\twith\tthe\tAAP’s\trecommendation\tto\tkeep\tall\tinfants\tunder\tthe\tage\tof\t6
|
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months\tout\tof\tdirect\tsunlight,\texclusively\tand\tpartially\tbreastfed\tinfants\tare\tat\thigh\trisk\tfor\tvitamin\nD\tdeficiency\t(\nAAP,\t2016\n).\tFor\tthe\tprevention\tof\trickets\tand\tvitamin\tD\tdeficiency,\ta\tminimum\tvitamin\nD\tintake\tof\t400\tIU\tper\tday\tshortly\tafter\tbirth\tis\trecommended\tfor\n\tall\tinfants.\tAll\tbreastfed\tinfants
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all\tinfants.\tAll\tbreastfed\tinfants\nneed\ta\tvitamin\tD\tsupplement\tof\t400\tIU\tper\tday.\tFormula-fed\tinfants\twho\tconsume\tless\tthan\t1000\tmL\nof\tformula\tper\tday\talso\tneed\tsupplementation\t(\nAntonucci\tet\tal,\t2018\n).\nThere\tappears\tto\tbe\ta\thigher\trisk\tof\trickets\tamong\tunsupplemented,\tbreastfed\tinfants\tand\tchildren
|
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] |
with\tdark\tskin.\tBecause\ta\tvariety\tof\tenvironmental\tand\tfamily\tlifestyle\tfactors\tcan\taffect\tsunlight\nexposure\tand\tabsorption\tof\tvitamin\tD,\tthe\tAAP\trecommendations\tto\tprovide\tsupplemental\tvitamin\tD\nare\tappropriate\tfor\tall\tinfants.\tSupplementation\tup\tto\t800\tIU\tof\tvitamin\tD\tper\tday\tmay\tbe\tneeded\tfor
|
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] |
infants\tat\thigher\trisk,\tsuch\tas\tpremature\tinfants,\tdark-skinned\tinfants\tand\tchildren,\tand\tthose\twho\nreside\tin\tnorthern\tlatitudes\tor\tat\thigher\taltitudes\t(\nAntonucci\tet\tal,\t2018\n;\tsee\t\nAppendix\t38\n).\nVitamin\tK\nThe\tvitamin\tK\trequirements\tof\tthe\tneonate\tneed\tspecial\tattention.\tDeficiency\tmay\tarise\tbecause
|
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newborns\tdo\tnot\tstore\tvitamin\tK\tand\ttheir\tgut\tbacteria\tis\tnot\tdeveloped\tenough\tto\tsupply\tthe\nneeded\tamount.\tLow\tvitamin\tK\tcan\thappen\tin\tany\tinfant,\tregardless\tof\tgender\tor\tethnicity,\tand\nresults\tin\tbleeding\tor\themorrhagic\tdisease.\tThis\tcondition\tis\tmore\tcommon\tin\tbreastfed\tinfants\tthan\nin\tformula-fed
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