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aspiration.\tGood\toral\thygiene\tshould\tbe\temphasized\tin\tthese\tsituations\tbecause\tthe\tthickening\tagent\nmay\tcontain\tfermentable\tcarbohydrate\tand\tcan\tbe\tsticky,\n\tand\tthe\ttype\tof\tdysphagia\tmay\tcontribute\nto\tinadequate\tclearing\tof\tfood\tfrom\tthe\toral\tcavity.\nFermentable\tcarbohydrates\tsuch\tas\tcandy,\tcrackers,\tcookies,\tpastries,\tpretzels,\tsnack\tcrackers,
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chips,\tand\teven\tfruits\tshould\tbe\teaten\twith\tmeals.\tNotably,\t“fat-free”\tsnack\tand\tdessert\titems\tand\n“baked”\tchips\tand\tsnack\tcrackers\ttend\tto\thave\ta\thigher\tsimple\tsugar\tconcentration\tthan\ttheir\nhigher-fat-containing\n\tcounterparts.\nTooth\tloss\tand\tdentures\nTooth\tloss\t(\nedentulism\n)\tand\tremovable\tprostheses\t(dentures)\tcan\thave\ta\tsignificant\teffect\ton
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dietary\thabits,\tmasticatory\tfunction,\tolfaction,\tand\tnutritional\tadequacy.\tAs\tdentition\tstatus\tdeclines,\nmasticatory\tperformance\tis\tcompromised\tand\tmay\thave\ta\tnegative\teffect\ton\tfood\tchoices,\tresulting\nin\tdecreased\tintake\tof\tmeat,\twhole\tgrains,\tfruits,\tand\tvegetables\n\t(\nTsakos\tet\tal,\t2010\n).\tThis\tproblem
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(\nTsakos\tet\tal,\t2010\n).\tThis\tproblem\nis\tmore\tpronounced\tin\tolder\tadults,\twhose\tappetite\tand\tintake\tmay\tbe\tcompromised\tfurther\tby\nchronic\tdisease,\tsocial\tisolation,\tand\tthe\tuse\tof\tmultiple\tmedications\t(see\t\nChapter\t19\n).\nDentures\tmust\tbe\tchecked\tperiodically\tby\ta\tdental\tprofessional\tfor\tappropriate\tfit.\tChanges\tin
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after\tdenture\tplacement,\tmany\tindividuals\tmay\texperience\tdifficulty\tbiting\tand\tchewing.\tThe\tfoods\nfound\tto\tcause\tthe\tgreatest\tdifficulty\n\tfor\tpersons\twith\tcomplete\tdentures\tinclude\tfresh\twhole\tfruits\nand\tvegetables\t(e.g.,\tapples\tand\tcarrots),\thard-crusted\tbreads,\tand\twhole\tmuscle\tmeats.\tTherefore
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dietary\tassessment\tand\tcounseling\trelated\tto\toral\thealth\tshould\tbe\tprovided\tto\tthe\tdenture\twearer.\nSimple\tguidelines\tshould\tbe\tprovided\tfor\tcutting\tand\tpreparing\tfruits\tand\tvegetables\tto\tminimize\tthe\nneed\tfor\tbiting\tand\treduce\tthe\tamount\n\tof\tchewing.\tThe\timportance\tof\tpositive\teating\thabits\tmust\tbe
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of\tchewing.\tThe\timportance\tof\tpositive\teating\thabits\tmust\tbe\nstressed\tas\ta\tcomponent\tof\ttotal\thealth.\tOverall,\tguidelines\tthat\treinforce\tthe\timportance\tof\ta\nbalanced\tdiet\tshould\tbe\tpart\tof\tthe\troutine\tcounseling\tgiven\tto\tall\tpatients.\nOther\toral\tdisorders
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Other\toral\tdisorders\nOral\tdiseases\textend\tbeyond\tdental\tcaries.\tDeficiencies\tof\tseveral\tvitamins\t(riboflavin,\tfolate,\tB\n12\n,
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and\tC)\tand\tminerals\t(iron\tand\tzinc)\n\tmay\tbe\tdetected\tfirst\tin\tthe\toral\tcavity\tbecause\tof\tthe\trapid\ntissue\tturnover\tof\tthe\toral\tmucosa.\tPeriodontal\tdisease\tis\ta\tlocal\tand\tsystemic\tdisease.\tSelect\nnutrients\tplay\ta\trole,\tincluding\tvitamins\tA,\tC,\tand\tE;\tfolate;\tbeta-carotene;\tand\tthe\tminerals\tcalcium,\nphosphorus,\tand\tzinc\t(see\t\nChapter\t5\n).
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phosphorus,\tand\tzinc\t(see\t\nChapter\t5\n).\nOral\tcancer,\toften\ta\tresult\tof\ttobacco\tand\talcohol\tuse,\tcan\thave\ta\tsignificant\teffect\ton\teating\n\tability\nand\tnutritional\tstatus.\tThis\tproblem\tis\tcompounded\tby\tthe\tincreased\tcaloric\tand\tnutrient\tneeds\tof\npersons\twith\toral\tcarcinomas.\tIn\taddition,\tsurgery,\tradiation\ttherapy,\tand\tchemotherapy\tare
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modalities\tused\tto\ttreat\toral\tcancer\tthat\talso\tcan\taffect\tdietary\tintake,\tappetite,\tand\tthe\tintegrity\tof\nthe\toral\tcavity.\tSome\tbut\tnot\tall\tproblems\taffecting\tthe\toral\tcavity\tare\tdiscussed\there\twith\trelevant\nnutrition\tcare.\tPatients\tmay\ttry\tover-the-counter\tnatural\tproducts\tto\tprevent\tor\ttreat\toral\tdisease\tor\nconditions\t(see\t\nClinical\tInsight:
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conditions\t(see\t\nClinical\tInsight:\n\tNatural\tProducts\tin\tOral\tHealth\n).\nCLINICAL\tINSIGHT\nNatural\tProducts\tin\tOral\tHealth\nNatural\tproducts\tinclude\therbal\tand\tdietary\tsupplements\tand\tprobiotics\t(\nNational\tCenter\tfor\nComplementary\tand\tIntegrative\tHealth\t[NCCIH],\t2015\n).\tThe\tfollowing\tlists\tsome\n\therbal\tand
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).\tThe\tfollowing\tlists\tsome\n\therbal\tand\ndietary\tsupplements\tthat\tmay\tbe\tused\tto\tprevent\tor\ttreat\toral\thealth\tissues.\tSee\t\nChapter\t11\n\tfor\nmore\tinformation\tabout\tthe\tefficacy\tand\tsafety\tof\tnatural\tproducts\tbefore\tchoosing\tto\tuse\tthem\tin\naddition\tto\tor\tin\tplace\tof\tconventional\ttherapy.\nOral\nUse(s)\nNatural\nProduc\nt\nUse\nConsiderations\nMucositis
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Oral\nUse(s)\nNatural\nProduc\nt\nUse\nConsiderations\nMucositis\nHyaluronic\nacid\nTopically\t(oral\tgel)\nGerman\nchamom\nile\nOral\trinse\nMay\tcause\tallergic\treaction\tin\tindividuals\nsensitive\tto\tthe\tdaisy\tfamily.\nGlutamine\nOral\trinse\nIodine\nOral\trinse\t(in\tchemotherapy\ntreatment)\nKaolin\nOral\trinse\t(in\tradiation\ttreatment)\nAloe\nOral\trinse
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treatment)\nKaolin\nOral\trinse\t(in\tradiation\ttreatment)\nAloe\nOral\trinse\nOnly\tthe\tgel\tshould\tbe\tingested.\tAvoid\nwhole\n\tleaf\tand\taloe\tlatex.\nMucosal\nlesions\nSlippery\nelm\nTopically\t(lozenges)\nPeriodontal\ndisease\nCoenzyme\nQ\n10\nSystemically\nXylitol\nIn\tchewing\tgum\tor\tin\tplace\tof\nfermentable\tcarbohydrate\nNatural\tMedicines\tComprehensive\tDatabase\t(
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fermentable\tcarbohydrate\nNatural\tMedicines\tComprehensive\tDatabase\t(\nwww.naturaldatabase.com\n).\nPeriodontal\tdisease\nPathophysiology\nPeriodontal\tdisease\n\tis\tan\tinflammation\tof\tthe\tgingiva\twith\tinfection\tcaused\tby\toral\tbacteria\n\tand\nsubsequent\tdestruction\tof\tthe\ttooth\tattachment\tapparatus.\tUntreated\tdisease\tresults\tin\ta\tgradual
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gingival\tand\timmune\tsystem\tintegrity,\tand\tthere\tis\tnow\tevidence\nthat\tsome\tantioxidants\tcan\tmediate\tthe\tinflammation\tassociated\twith\tperiodontal\tdisease\t(\nNajeeb\tet\nal,\t2016\n).\tWhen\tperiodontal\tdisease\tcauses\tpain\tand\tavoidance\tof\tfoods,\tnutrient\tintake\tmay\tbe\nlimited\tand\tshould\tbe\tmonitored\t(\nStaudte\tet\tal,\t2012
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adequate\tnutrients\tare\n\tneeded\tto\tregenerate\ttissue\tand\tsupport\timmunity\tto\tprevent\tinfection.\nAdequacy\tof\tcalories,\tprotein,\tand\tmicronutrients\tshould\tbe\tpart\tof\tthe\tpostoperative\tcare\tplan.\nOral\tmanifestations\tof\tsystemic\tdisease\nAcute\tsystemic\tdiseases\tsuch\tas\tcancer\tand\tinfections,\tas\twell\tas\tchronic\tdiseases\tsuch\tas\tdiabetes
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mellitus,\tautoimmune\tdiseases,\tand\tchronic\tkidney\tdisease,\tare\tcharacterized\tby\toral\n\tmanifestations\nthat\tmay\talter\tthe\tdiet\tand\tnutritional\tstatus.\tCancer\ttherapies,\tincluding\tirradiation\tof\tthe\thead\tand\nneck\tregion,\tchemotherapy,\tand\tsurgeries\tto\tthe\toral\tcavity,\thave\ta\tsignificant\teffect\ton\tthe\tintegrity
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of\tthe\toral\tcavity\tand\ton\tan\tindividual’s\teating\tability,\twhich\tmay\tconsequently\taffect\tnutrition\tstatus\n(see\t\nChapter\t35\n).\nIf\tthe\tcondition\tof\tthe\tmouth\tadversely\taffects\tone’s\n\tfood\tchoices,\tthe\tperson\twith\tchronic\tdisease\nmay\tnot\tbe\table\tto\tfollow\tthe\toptimal\tdiet\tfor\tmedical\tnutrition\ttherapy.\tFor\texample,\tpoorly
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taste\tsensation,\tor\tsalivary\nproduction.\tPhenytoin\t(Dilantin)\tmay\tcause\tsevere\tgingivitis.\tMany\tof\tthe\tprotease\tinhibitor\tdrugs\nused\tto\ttreat\tHIV\tand\tacquired\timmune\tdeficiency\tsyndrome\t(AIDS)\tare\tassociated\twith\taltered\ntaste\tand\tdry\tmouth.\tReduced\tsaliva\tcontributes\tto\tincreased\tcaries\trisk\tand\talso\tmay\talter\tthe
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ability\tto\tform\ta\tbolus\tand\tswallow\tfoods,\tespecially\tdry\tfoods\tthat\tcrumble\n\twith\tmastication.\tCare\nshould\tbe\ttaken\tto\tassess\tthe\teffects\tof\tmedication\ton\tthe\toral\tcavity\tand\tminimize\tthese\teffects\nusing\talterations\tin\tdiet\tor\tdrug\ttherapy.\nDiabetes\tmellitus
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using\talterations\tin\tdiet\tor\tdrug\ttherapy.\nDiabetes\tmellitus\nDiabetes\tis\tassociated\twith\tseveral\toral\tdiseases,\tmany\tof\twhich\toccur\tonly\tin\tperiods\tof\tpoor\nglucose\tcontrol.\tThese\tinclude\tburning\tmouth\tsyndrome,\tperiodontal\tdisease,\tcandidiasis,\tdental\ncaries,\tand\txerostomia.\n\tThe\tmicroangiopathic\tconditions\tseen\tin\tdiabetes,\talong\twith\taltered
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The\tmicroangiopathic\tconditions\tseen\tin\tdiabetes,\talong\twith\taltered\nresponses\tto\tinfection,\tcontribute\tto\trisk\tof\tperiodontal\tdisease\tin\taffected\tpersons.\tTooth\tinfection,\nmore\tcommon\tin\tthose\twith\tdiabetes,\tleads\tto\tdeterioration\tof\tdiabetes\tcontrol\t(\nAl-Khabbaz,\t2014\n).\nFungal\tinfections
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Al-Khabbaz,\t2014\n).\nFungal\tinfections\nOropharyngeal\tfungal\tinfections\tmay\tcause\ta\tburning,\tpainful\tmouth\tand\tdysphagia.\tThe\tulcers\tthat\naccompany\n\tviral\tinfections\tsuch\tas\therpes\tsimplex\tand\tcytomegalovirus\tcause\tpain\tand\tcan\tlead\tto\nreduced\toral\tintake.\tVery\thot\tand\tcold\tfoods\tor\tbeverages,\tspices,\tand\tsour\tor\ttart\tfoods\tmay\tcause
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integrity\tof\tthe\toral\tmucosa.\tThick,\tropy\tsaliva\tis\toften\tthe\tresult\tof\tradiation\ttherapy\tto\tthe\thead\nand\tneck\tarea,\tcausing\n\txerostomia.\tDietary\tmanagement\tfocuses\ton\tthe\trecommendations\tdescribed\nearlier\tfor\txerostomia,\talong\twith\tmodifications\tin\tfood\tconsistency\tafter\tsurgery\t(see\t\nChapters\t35\nand\t\n39\n).\nHIV\tinfection\tand\tAIDS
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Chapters\t35\nand\t\n39\n).\nHIV\tinfection\tand\tAIDS\nViral\tand\tfungal\tinfections,\tstomatitis,\txerostomia,\tperiodontal\tdisease,\tand\tKaposi’s\tsarcoma\tare\noral\tmanifestations\tof\tHIV\tthat\tcan\tcause\tlimitations\tin\tnutrient\tintake\tand\tresult\tin\tweight\n\tloss\tand\ncompromised\tnutrition\tstatus.\tThese\tinfections\toften\tare\tcompounded\tby\ta\tcompromised\timmune
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-0.03474993631243706, -0.10258417576551437, -0.007221394218504429, -0.04490293934941292, 0.027529940009117126, -0.053758829832077026, 0.07796896249055862, 0.018102824687957764, 0.0006408741464838386, 0.04459971934556961, 0.01895420253276825, -0.044996511191129684, -0.0715261846780777, -0.06981161236763, -0.00806963536888361, 0.03545728325843811, 0.12692496180534363, -0.0677482932806015, -0.009084568358957767, -0.10121570527553558, 0.03604811429977417, -0.10481977462768555, 0.031038369983434677, 0.04167672246694565, 0.053701676428318024, 0.039254676550626755, -0.068820521235466, -0.003235277021303773, 0.021573230624198914, 0.04135585576295853, -0.028055746108293533, -0.041752323508262634, 0.043705783784389496, -0.004506535362452269, -0.004960998427122831, 0.05467017740011215, -0.07700187712907791, -0.08368534594774246, -0.0005761096836067736, 0.07327410578727722, -0.06874793767929077, 0.09804289788007736, -0.008361811749637127, 0.010501058772206306, -0.025161199271678925, -0.05518978834152222, -0.008599056862294674, -0.037595562636852264, 0.04998007044196129, 0.12179746478796005, -0.03795100003480911, -0.007251758128404617, 0.013367816805839539, 0.0652441456913948, -0.04686366394162178, -0.012596377171576023, -0.10264215618371964, -0.058245718479156494, 0.02993486449122429, 0.006380258593708277, -0.018241288140416145, 0.01859389804303646, -0.008101009763777256, 0.03516370430588722, -0.06766773015260696, -0.06793322414159775, -0.04373779520392418, 0.042464304715394974, -0.005374615080654621, -0.016922462731599808, 0.002820368856191635, -0.0656108558177948, -0.11861970275640488, 0.07342328131198883, 0.017883578315377235, 0.050065185874700546, 0.018758585676550865, -0.026758233085274696, -0.0016968157142400742, -0.05548791214823723, -0.05154101923108101, 0.037307318300008774, 0.01987842284142971, 0.043222587555646896, -0.016265522688627243, -0.005403003189712763, 0.0016238975804299116, 0.025044774636626244, 0.04371001943945885, -0.0327681265771389, 0.026322398334741592, 0.0024762798566371202, 0.031149331480264664, 0.09466637670993805, -4.974709000293842e-8, 0.07061789184808731, 0.007205573841929436, -0.03365102782845497, -0.018027497455477715, 0.012221227400004864, 0.002106998348608613, -0.0005553057417273521, 0.05347128212451935, 0.00034910027170553803, 0.027888964861631393, 0.00464367913082242, 0.10778389126062393, -0.0102574797347188, -0.03158179298043251, 0.06096049025654793, 0.013410399667918682, 0.05622308328747749, 0.08066362887620926, -0.012758824042975903, -0.0687817856669426, -0.047161079943180084, 0.030090482905507088, 0.01312174927443266, -0.04100233316421509, -0.06041941046714783, 0.013149741105735302, -0.019545432180166245, 0.015177346765995026, 0.00968065857887268, -0.003203541273251176, 0.045955635607242584, -0.02512378618121147, -0.03793412074446678, -0.041757576167583466, 0.000351461028913036, 0.036037445068359375, -0.012836243025958538, -0.034593015909194946, 0.04308713227510452, 0.0606512725353241, 0.021533353254199028, -0.01461784541606903, 0.03488604351878166, 0.05824301391839981, 0.04315311089158058, -0.055644650012254715, -0.012358198873698711, 0.0684882327914238, 0.023437906056642532, -0.10771764814853668, -0.029338516294956207, 0.09148230403661728, 0.02435259334743023, 0.005458091851323843, -0.09141448885202408, 0.02672641910612583, 0.14532244205474854, 0.04094500094652176, 0.0027755459304898977, 0.017738420516252518, 0.04629207402467728, 0.011201989836990833, 0.027588510885834694, 0.022597502917051315 ]
response,\tpreexisting\tmalnutrition,\tand\tgastrointestinal\tconsequences\tof\tHIV\tinfection\t(see\t\nChapter\n36\n).\tViral\tdiseases,\tincluding\therpes\tsimplex\tand\tcytomegalovirus,\tresult\tin\tpainful\tulcerations\tof\tthe\nmucosa.\nStomatitis\n,\tor\tinflammation\tof\tthe\toral\tmucosa,\tcauses\tsevere\tpain\tand\tulceration\n\tof\tthe\tgingiva,
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0.014890442602336407, -0.0586860328912735, 0.06835521012544632, 0.04421640932559967, -0.03178519010543823, -0.04569046199321747, 0.06427054107189178, 0.03476034849882126, -0.1205289289355278, -0.014951792545616627, 0.037877291440963745, 0.004575669765472412, 0.007598014082759619, -0.088033027946949, 0.032479941844940186, 0.08709970861673355, -0.012230204418301582, 0.05007794871926308, -0.020090226083993912, 0.07375708222389221, 0.0664946660399437, 0.05428697168827057, -0.008777419105172157 ]
of\tthe\tgingiva,\noral\tmucosa,\tand\tpalate,\twhich\tmakes\teating\tpainful.\t\nCandidiasis\n\ton\tthe\ttongue,\tpalate,\tor\nesophagus\tcan\tmake\tchewing,\tsucking,\tand\tswallowing\tpainful\t(odynophagia),\tthus\tcompromising\nintake.\t\nTable\t24.3\n\toutlines\tthe\teffects\tof\tassociated\toral\tinfections.
[ 0.03900550678372383, -0.0476340726017952, 0.0423174723982811, -0.009055731818079948, -0.13631445169448853, -0.02081586793065071, 0.05564061552286148, 0.006376820616424084, 0.044024012982845306, 0.04125590622425079, 0.06769755482673645, 0.00025528285186737776, 0.04005137458443642, 0.01712041161954403, -0.04411726072430611, 0.005786535795778036, -0.0005104214651510119, -0.0006427578045986593, -0.003734271042048931, -0.022164272144436836, 0.03881538659334183, 0.1611984819173813, 0.044565655291080475, -0.014335280284285545, -0.012004181742668152, 0.013960755430161953, -0.040774647146463394, -0.057018037885427475, 0.018532758578658104, -0.021939367055892944, -0.10193606466054916, 0.02277146279811859, -0.0411730594933033, -0.00912095233798027, 0.013840853236615658, 0.029152633622288704, -0.015057680197060108, 0.03779744356870651, 0.09048055857419968, 0.04072356969118118, 0.003318801522254944, -0.040682777762413025, -0.06737358123064041, -0.017305828630924225, 0.0013117908965796232, -0.0023808907717466354, -0.04642775282263756, -0.030322447419166565, -0.02284977398812771, 0.008439813740551472, -0.033196184784173965, -0.041817475110292435, -0.09069254994392395, 0.10265588015317917, -0.01960175111889839, -0.025707587599754333, -0.015978828072547913, -0.024297412484884262, -0.016308143734931946, 0.007293100003153086, -0.02010892704129219, 0.005530119873583317, -0.04231186956167221, 0.05268636345863342, -0.002737794304266572, -0.007919375784695148, 0.018060138449072838, 0.014154976233839989, 0.01740526594221592, 0.07375342398881912, -0.039414044469594955, -0.024613143876194954, 0.0184937734156847, 0.0712650716304779, -0.07028099149465561, 0.013238096609711647, 0.09655353426933289, -0.05513732507824898, -0.027570856735110283, -0.022351454943418503, -0.05432314798235893, 0.12143512070178986, 0.048525817692279816, 0.0027372553013265133, -0.05253392085433006, 0.01567087508738041, -0.011076375842094421, 0.040009379386901855, -0.009724992327392101, 0.021886533126235008, 0.018956946209073067, -0.09024360030889511, -0.03175663948059082, -0.012946981005370617, 0.012443475425243378, -0.04946870356798172, -0.01342036109417677, -0.052194416522979736, -0.009818634949624538, -0.02116313949227333, -0.055460453033447266, -0.05563455447554588, 0.042358268052339554, 0.006618902087211609, -0.022328486666083336, 0.008620726875960827, -0.048180676996707916, -0.14680267870426178, 0.04511028528213501, -0.008072820492088795, -0.06480646878480911, -0.01851765438914299, 0.07960957288742065, -0.07819217443466187, 0.016975833103060722, -0.02299988828599453, -0.08610919117927551, -0.0010987658752128482, 0.10693654417991638, 0.03473927453160286, 0.010549208149313927, -0.08489463478326797, -0.00288973655551672, 0.035246577113866806, -0.050435870885849, -0.03843334689736366, -0.01477162353694439, 5.610736014698033e-34, 0.08905399590730667, 0.04926304146647453, 0.009551783092319965, 0.024053635075688362, 0.05434521660208702, 0.04900148883461952, -0.039437346160411835, -0.057421278208494186, 0.004299927968531847, 0.07397598773241043, -0.07487479597330093, -0.006660967133939266, -0.012684584595263004, 0.06270236521959305, -0.04579303786158562, -0.07031653821468353, -0.053773097693920135, 0.05082390084862709, -0.018140044063329697, -0.01879175193607807, -0.016949208453297615, 0.16777469217777252, 0.029301775619387627, -0.03093215823173523, -0.05171806365251541, -0.02749173529446125, -0.012212282977998257, -0.04178420454263687, -0.010485904291272163, 0.030917469412088394, 0.030221423134207726, -0.0348057821393013, -0.00871937908232212, 0.004793456289917231, -0.049325648695230484, -0.011759351007640362, -0.017951948568224907, 0.03259936720132828, -0.013335706666111946, -0.021079352125525475, -0.03584740683436394, 0.015165823511779308, -0.029494494199752808, 0.07284621894359589, 0.01721755973994732, -0.0030836870428174734, -0.034627582877874374, -0.0040674651972949505, 0.00816428940743208, -0.020126668736338615, 0.04663335531949997, 0.008770166896283627, 0.07212311029434204, -0.06465132534503937, -0.014560296200215816, -0.010263839736580849, -0.002443107310682535, 0.00617995485663414, 0.008098093792796135, 0.060569848865270615, 0.03407047688961029, 0.012307732366025448, 0.05625174567103386, -0.10856998711824417, 0.04356228560209274, -0.046664752066135406, -0.153791606426239, -0.06567678600549698, 0.027284685522317886, -0.050709374248981476, -0.07020639628171921, 0.0016908034449443221, 0.004730301443487406, 0.0346299484372139, 0.05562736093997955, -0.016869667917490005, 0.054429300129413605, -0.04615795239806175, 0.009553494863212109, -0.04275648295879364, -0.06326501816511154, -0.09062891453504562, 0.010012873448431492, 0.029224004596471786, -0.005789999384433031, -0.03733200207352638, -0.0017530566547065973, -0.05424768105149269, -0.011952104978263378, 0.051047150045633316, -0.061268340796232224, 0.07016661018133163, 0.017334366217255592, -0.03002835251390934, -0.07269616425037384, -2.2278677906814333e-33, -0.039279282093048096, 0.01604509726166725, -0.09818239510059357, 0.044108323752880096, -0.059703465551137924, 0.04467092081904411, -0.01661072112619877, 0.12202200293540955, 0.013860407285392284, -0.053619638085365295, 0.04535398632287979, 0.01876879669725895, -0.03275243565440178, -0.07963404059410095, -0.03563150763511658, -0.02481243945658207, 0.02684062346816063, 0.11222903430461884, -0.0022686852607876062, -0.017706045880913734, -0.059266459196805954, 0.00442404393106699, -0.1519981324672699, 0.02421814203262329, 0.04856410622596741, 0.09061054140329361, 0.04593057557940483, -0.07108449935913086, -0.008098854683339596, 0.043758489191532135, 0.054573904722929, -0.0022898276802152395, -0.01460617408156395, 0.013976017944514751, -0.019232746213674545, 0.043876856565475464, 0.025087453424930573, -0.05460602045059204, -0.08777961134910583, -0.05873720347881317, 0.07593568414449692, 0.01208587922155857, 0.1463567018508911, -0.008201255463063717, 0.0249937754124403, 0.004693490918725729, -0.06976881623268127, -0.07379388064146042, -0.04551956057548523, 0.06863339245319366, 0.09294384717941284, 0.018088482320308685, -0.02099619247019291, 0.026507070288062096, 0.05371153727173805, -0.02094431035220623, -0.030672861263155937, -0.11537496745586395, -0.055906422436237335, -0.06461471319198608, -0.02087373472750187, -0.018770799040794373, 0.031100284308195114, 0.0027766090352088213, 0.06798385083675385, -0.04822211340069771, -0.05585310235619545, -0.041228290647268295, 0.060986053198575974, -0.04984879866242409, -0.001166158588603139, -0.007048995234072208, -0.0888151079416275, -0.11187823116779327, 0.09377938508987427, -0.02196216583251953, 0.027776852250099182, -0.07623862475156784, -0.03247128427028656, -0.0016796444542706013, -0.019414789974689484, 0.02280612848699093, 0.06725306808948517, -0.023303508758544922, -0.02425234578549862, -0.0218548271805048, -0.003278210526332259, 0.028390448540449142, 0.0555974580347538, 0.07821876555681229, 0.009916805662214756, 0.07729847729206085, -0.046615272760391235, 0.023638537153601646, 0.11611630022525787, -4.580051182756506e-8, 0.03263228386640549, -0.059567686170339584, 0.019670268520712852, -0.00745358457788825, 0.026373932138085365, -0.06299592554569244, 0.07196804136037827, 0.08861695230007172, -0.046500738710165024, -0.013859249651432037, 0.024674570187926292, 0.10002382844686508, -0.047315165400505066, -0.03411664068698883, 0.09441427886486053, 0.03476083278656006, 0.014607260003685951, 0.08627114444971085, -0.016185808926820755, -0.09353616833686829, -0.05469003692269325, 0.07320915907621384, 0.01717321202158928, -0.019369252026081085, -0.02655961737036705, 0.009006923995912075, -0.042951665818691254, 0.00014193973038345575, -0.006509758066385984, 0.006415069568902254, 0.06923699378967285, 0.017554612830281258, -0.04122376814484596, -0.06648281961679459, -0.06688208878040314, 0.05266254022717476, -0.015267623588442802, -0.0357423759996891, -0.004263344686478376, 0.08000685274600983, 0.017232531681656837, 0.01834019646048546, 0.00934567116200924, 0.0353994257748127, 0.019427191466093063, -0.06858719140291214, 0.012186815030872822, 0.08602923899888992, 0.008053727447986603, -0.050650015473365784, -0.010292247869074345, 0.14269010722637177, 0.01306840032339096, -0.0325859934091568, -0.05968724191188812, 0.03672735020518303, 0.05468059331178665, 0.02761327289044857, -0.012798036448657513, -0.005339448805898428, 0.05334404110908508, 0.08937378972768784, 0.08756118267774582, -0.040390145033597946 ]
TABLE\t24.3\nEffects\tof\tOral\tInfections\nLocation\nProblem\nEffect\nDiet\tManagement\nOral\tcavity\nCandidiasis,\tKS,\nherpes,\nstomatitis\nPain,\tinfection,\tlesions,\taltered\nability\tto\teat,\tdysgeusia\nIncrease\tkilocalorie\tand\tprotein\nintake;\tadminister\toral\nsupplements;\tprovide\tcaries\nrisk\treduction\teducation\nXerostomia\nIncreased\tcaries\trisk,\tpain,\tdifficulty
[ 0.016950193792581558, -0.08289606869220734, 0.016515567898750305, -0.005775516387075186, -0.09038294106721878, 0.012440136633813381, 0.08026568591594696, 0.035322029143571854, -0.056272536516189575, 0.07975326478481293, 0.12653733789920807, -0.033549509942531586, 0.029107898473739624, 0.024403652176260948, -0.053449392318725586, -0.00014914845814928412, 0.007603782694786787, -0.003594281617552042, -0.031049717217683792, 0.017335299402475357, 0.03086095117032528, 0.12611110508441925, 0.064613476395607, -0.017316965386271477, -0.023704802617430687, -0.004188244231045246, -0.037270039319992065, -0.01662902534008026, -0.02663896232843399, -0.043207693845033646, -0.12352878600358963, 0.04974314942955971, 0.004096330609172583, -0.01082948874682188, 0.05276041105389595, -0.01812022365629673, -0.06455020606517792, 0.0024324527475982904, 0.06260034441947937, 0.060486700385808945, -0.0025676668155938387, -0.05891920626163483, -0.04409603402018547, 0.07072634249925613, 0.027928946539759636, -0.020349809899926186, -0.043823741376399994, -0.04116000980138779, -0.004712337628006935, 0.03794443607330322, -0.07191043347120285, -0.01657048426568508, -0.06291554868221283, 0.09442079812288284, 0.014815157279372215, -0.0565243698656559, -0.06214842200279236, -0.048184920102357864, -0.046448029577732086, 0.01852196268737316, -0.003680869471281767, -0.017907030880451202, 0.003968310542404652, 0.01358701754361391, -0.021830108016729355, 0.0499773807823658, -0.009844940155744553, -0.011978840455412865, 0.019488275051116943, 0.08062505722045898, -0.025105493143200874, -0.008022292517125607, -0.037341710180044174, 0.11496350914239883, -0.05334216356277466, 0.014056642539799213, 0.07868966460227966, -0.06186046823859215, 0.004499054979532957, -0.012097485363483429, -0.10084108263254166, 0.1144137978553772, 0.03548600897192955, 0.040253520011901855, -0.01969343051314354, -0.03697351738810539, -0.00033345064730383456, 0.0481436587870121, -0.044039536267519, 0.024715151637792587, 0.036342915147542953, -0.062119901180267334, -0.007033269386738539, -0.04502452164888382, -0.055377475917339325, -0.03653629496693611, 0.026997016742825508, -0.08194749057292938, -0.0020452935714274645, -0.03817182034254074, -0.05830184742808342, -0.05064529925584793, 0.022849412634968758, 0.024452824145555496, -0.09348098188638687, -0.01992945373058319, 0.006966716144233942, -0.11244890838861465, 0.04167287424206734, -0.004902098327875137, -0.04883008450269699, 0.03756069764494896, 0.04199334606528282, -0.09095114469528198, -0.013465424068272114, -0.018581997603178024, -0.0024090490769594908, -0.007926947437226772, 0.18725717067718506, 0.04788793623447418, -0.011975896544754505, -0.03198244422674179, 0.04886671528220177, 0.04317031800746918, -0.06620781868696213, -0.025422662496566772, -0.03661259636282921, 2.100431897095812e-33, 0.0040597813203930855, 0.04024150222539902, 0.005902433767914772, 0.05466181039810181, 0.03431230038404465, 0.02897229976952076, -0.011659856885671616, -0.04783168435096741, -0.029444150626659393, 0.05031312629580498, -0.0708765909075737, 0.0006801111740060151, 0.009441964328289032, 0.08935551345348358, -0.0003536104049999267, -0.006574115250259638, -0.041919223964214325, 0.02926058880984783, -0.03591809794306755, 0.009592453949153423, -0.0009826536988839507, 0.15097492933273315, 0.045942675322294235, 0.011084940284490585, -0.08390192687511444, -0.03187165781855583, -0.04687613621354103, 0.002847004681825638, 0.020024865865707397, 0.013028590939939022, 0.032472752034664154, -0.0537680983543396, -0.00022163905669003725, -0.018185071647167206, -0.04142314940690994, 0.0027424648869782686, -0.011804095469415188, 0.02112201601266861, 0.03401655703783035, -0.004664316773414612, -0.036904964596033096, 0.016453377902507782, 0.021295923739671707, 0.07142803072929382, 0.07144297659397125, -0.016926255077123642, -0.008526905439794064, -0.03577224910259247, 0.003217047080397606, -0.008865232579410076, 0.004503822419792414, 0.004228752106428146, 0.06804220378398895, -0.048765793442726135, -0.0551728717982769, 0.010308968834578991, -0.042091336101293564, 0.04517006129026413, -0.021252023056149483, 0.08495794981718063, 0.032862212508916855, 0.05501681938767433, 0.041364848613739014, -0.07662702351808548, 0.029766954481601715, -0.006822009105235338, -0.15087568759918213, -0.09929384291172028, 0.00848313607275486, -0.02666333317756653, -0.07124535739421844, 0.023696867749094963, 0.03773647919297218, 0.038617007434368134, 0.0669008269906044, 0.015739677473902702, 0.019246917217969894, -0.08418506383895874, -0.011447316966950893, -0.10060261189937592, -0.05250009149312973, -0.08898932486772537, 0.026930401101708412, -0.010919622145593166, -0.05140862241387367, -0.05265219137072563, -0.024050435051321983, -0.044974349439144135, 0.015120502561330795, 0.024128125980496407, -0.013121661730110645, 0.06125538796186447, -0.03987030312418938, -0.044217269867658615, -0.08375754207372665, -3.8412690520155475e-33, -0.059308212250471115, 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Xerostomia\nIncreased\tcaries\trisk,\tpain,\tdifficulty\nwith\tmastication,\tlack\tof\tsaliva\tto\nform\tbolus,\ttendency\tof\tfood\tto\nstick,\n\tdysgeusia\nMoist,\tsoft,\tnonspicy\tfoods;\n“smooth”\tcool\tor\twarm\tfoods\nand\tfluids;\tcaries\trisk\treduction\neducation\nEsophagus\nCandidiasis,\therpes,\nKS,\ncryptosporidiosis\nDysphagia,\todynophagia\nTry\toral\tsupplementation\tfirst;\tif
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Dysphagia,\todynophagia\nTry\toral\tsupplementation\tfirst;\tif\nthat\tis\tunsuccessful,\tinitiate\nNG\tfeedings\tusing\ta\tsilastic\nfeeding\ttube\tor\tPEG\nCMV,\twith\tor\nwithout\nulceration\nDysphagia,\tfood\taccumulation\nPEG\nCMV\n,\tCytomegalovirus;\t\nKS\n,\tKaposi’s\tsarcoma;\t\nNG\n,\tnasogastric;\t\nPEG\n,\tpercutaneous\tendoscopic\tgastrostomy.\nXerostomia
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,\tnasogastric;\t\nPEG\n,\tpercutaneous\tendoscopic\tgastrostomy.\nXerostomia\nXerostomia\t(dry\tmouth)\tis\tseen\tin\tpoorly\tcontrolled\tdiabetes\tmellitus,\tSjögren’s\tsyndrome,\tother\nautoimmune\tdiseases,\tand\tas\ta\tconsequence\tof\tradiation\ttherapy\tand\tcertain\tmedications\t(\nBox\t24.3\n).
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Box\t24.3\n).\nXerostomia\tfrom\tradiation\ttherapy\tmay\tbe\tmore\tpermanent\tthan\tthat\tfrom\tother\tcauses.\tRadiation\ntherapy\n\tprocedures\tto\tspare\tthe\tparotid\tgland\tshould\tbe\timplemented\twhen\tpossible\tto\treduce\tthe\ndamage\tto\tthe\tsalivary\tgland.\tEfforts\tto\tstimulate\tsaliva\tproduction\tusing\tthe\tmedication\tpilocarpine
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and\tcitrus-flavored,\tsugar-free\tcandies\tmay\tease\teating\tdifficulty.\nBOX\t24.3\nMedications\tthat\tMay\tCause\tXerostomia\nAntianxiety\tagents\nAnticonvulsants\nAntidepressants\nAntihistamines\nAntihypertensives\nDiuretics\nNarcotics\nSedatives\nSerotonin\treuptake\tinhibitors\nTranquilizers
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Narcotics\nSedatives\nSerotonin\treuptake\tinhibitors\nTranquilizers\nIndividuals\twithout\tany\tsaliva\tat\tall\thave\tthe\tmost\tdifficulty\teating;\tartificial\tsalivary\tagents\tmay\nnot\toffer\tsufficient\trelief.\tLack\tof\tsaliva\timpedes\tall\taspects\tof\teating,\tincluding\tchewing,\tforming\ta
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bolus,\tswallowing,\tand\tsensing\ttaste;\tcauses\tpain;\tand\tincreases\tthe\trisk\tof\tdental\tcaries\tand\ninfections.\n\tDietary\tguidelines\tfocus\ton\tthe\tuse\tof\tmoist\tfoods\twithout\tadded\tspices,\tincreased\tfluid\nconsumption\twith\tand\tbetween\tall\tmeals\tand\tsnacks,\tand\tjudicious\tfood\tchoices.
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Problems\twith\tchewy\t(steak),\tcrumbly\t(cake,\tcrackers,\trice),\tdry\t(chips,\tcrackers),\tand\tsticky\n(peanut\tbutter)\tfoods\tare\tcommon\tin\tpersons\twith\tsevere\txerostomia.\tAlternatives\tshould\tbe\nsuggested,\tor\tthe\tfoods\tshould\tbe\tavoided\n\tto\tavert\tdysphagia\trisk.\tDrinking\twater\twith\ta\tlemon\tor
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to\tavert\tdysphagia\trisk.\tDrinking\twater\twith\ta\tlemon\tor\nlime\ttwist\tor\tcitrus-flavored\tseltzers\tor\tsucking\ton\tfrozen\ttart\tgrapes,\tberries,\tor\tsugar-free\tcandies\nmay\thelp.\tBecause\tthese\tfoods\tor\tbeverages\tmay\tcontain\tfermentable\tcarbohydrate\tor\tcontribute\tto
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Introduction\nThis\tsection\tcontains\tchapters\tthat\treflect\tthe\tevolution\tof\tnutritional\tscience,\tfrom\tthe\tidentification\nof\tnutrient\trequirements\tand\tthe\tpractical\tapplication\tof\tthis\tknowledge,\tto\tthe\tconcepts\tthat\trelate\nnutrition\tto\tthe\tprevention\tof\tchronic\tand\tdegenerative\tdiseases\tand\toptimization\tof\thealth.\tThe\trole
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of\tnutrition\tin\treducing\tinflammation,\ta\tmajor\tcontributor\tto\tchronic\tdisease,\tsupports\n\tthe\nawareness\tof\tdiet\tin\tdisease\tprevention\tand\tmanagement.\nMedical\tnutrition\ttherapy\t(MNT)\tincludes\tassessment,\tnutrition\tdiagnosis,\tinterventions,\nmonitoring,\tand\tevaluation\tof\tdisease.\tIn\tsome\tcases,\tMNT\tis\ta\tpowerful\tpreventive\tmeasure.\tThe
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provide\tnutrition\tcare.\tThe\tnutrition-related\tdisorders\tincluded\tin\tthis\tsection\tcan\tbe\tmanaged\tby\nchanges\tin\tdietary\tpractices\tbased\ton\tcurrent\tknowledge.\tThe\tgoal\tof\tMNT\tis\tto\tmove\tthe\tindividual\nfrom\tthe\tcontinuum\tof\tdisease\ttoward\n\tbetter\tnutritional\thealth\tand\toverall\twell-being.
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25\nMedical\tnutrition\ttherapy\tfor\nadverse\treactions\tto\tfood:\tAllergies\nand\tintolerances\nL.\tKathleen\tMahan,\tMS,\tRDN,\tCD,\tKathie\tMadonna\tSwift,\tMS,\tRDN,\tLDN,\tFAND\nKEY\tTERMS\nadverse\treactions\tto\tfood\nallergen\nallergen\timmunotherapy\t(AIT)\nanaphylaxis\nantibodies\nantigen\nantigen-presenting\tcell\t(APC)\natopic\tdermatitis\n“atopic\tmarch”\natopy\nbasophils
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atopic\tdermatitis\n“atopic\tmarch”\natopy\nbasophils\nB-cells\nB-regulatory\t(B-reg)\n\tcells\ncomponent\tresolved\tdiagnostics\t(CRD)\ncow’s\tmilk\tprotein\tallergy\t(CMPA)\ncross-reactivity\ncytokines\ndiamine\toxidase\t(DAO)\ndendritic\tcells\t(DCs)\ndouble-blind,\tplacebo-controlled\tfood\tchallenge\t(DBPCFC)\ndual-allergen\thypothesis\ndysbiosis\nelimination\tdiet
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dual-allergen\thypothesis\ndysbiosis\nelimination\tdiet\neosinophilic\tesophagitis\t(EoE)\neosinophilic\tgastroenteritis\t(EGE)\neosinophils\nepigenetic\nepitope\nFAILSAFE\tdiet\nFood\tAllergen\n\tLabeling\tand\tConsumer\tProtection\tAct\t(FALCPA)\nfood\tallergen–specific\tserum\tIgE\ttesting\nfood\tallergy\nfood\tand\tsymptom\trecord\nfood\tautoimmune\tor\timmune\treactivity
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food\tand\tsymptom\trecord\nfood\tautoimmune\tor\timmune\treactivity\nfood-dependent,\texercise-induced\tanaphylaxis\t(FDEIA)\nfood\tintolerance\nfood\tprotein–induced\tenterocolitis\tsyndrome\t(FPIES)\nfood\tprotein–induced\tproctocolitis\tor\tproctitis\t(FPIP)\nfood\tsensitivity\ngalactose-α-1,\t3-galactose\t(alpha-gal)
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granulocyte\ngut-associated\tlymphoid\ttissue\t(GALT)\nhistamine\nhistamine-N-methyltransferase\t(HNMT)\nincreased\tintestinal\tpermeability\tor\t“leaky\tgut”\nIgE-mediated\treactions\nimmunoglobulin\t(Ig)\ninflammatory\tmediators\nlatex-fruit\tsyndrome\tor\tlatex-food\tsyndrome\nlipid\ttransfer\tprotein\tsyndrome\t(LTPS)\nlymphocyte\nmast\tcells\nmicrobiome
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lymphocyte\nmast\tcells\nmicrobiome\nnon–IgE-mediated\treactions\noral\tallergy\tsyndrome\t(OAS)\noral\tfood\tchallenge\t(OFC)\noral\ttolerance\npollen-food\tallergy\tsyndrome\t(PFAS)\nprebiotics\nprecautionary\tallergen\tlabeling\t(PAL)\nprobiotics\nsensitivity-related\tillness\t(SRI)\nsensitization\nsix-food\telimination\tdiet\t(SFED)\nskin-prick\ttest\t(SPT)
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sensitization\nsix-food\telimination\tdiet\t(SFED)\nskin-prick\ttest\t(SPT)\nstep\tup\t2-4-6-food\telimination\tdiets\nsystemic\tnickel\tallergy\tsyndrome\t(SNAS)\nT-cells\nTh\tcells\nTh1\tcells\nTh2\tcells\nT-regulatory\t(T-reg)\tcells\nT-suppressor\tcells\ntyramine\nAdverse\treactions\tto\tfood\tare\tcommon\tand\timplicated\tin\tmany\tconditions\tas\ta\tresult\tof\tthe\tinvolvement
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of\tmajor\torgan\tsystems,\tincluding\tthe\tdermatologic,\trespiratory,\tgastrointestinal,\tand\tneurologic\tsystems.\nThe\tmanagement\tof\tadverse\treactions\tto\tfood\tis\tcomplex\tbecause\tof\tthe\tdiverse\tresponse\tby\twhich\tthe\nbody\treacts\tto\tfood\tand\tfood\tcomponents\tand\tthe\tmultifaceted\n\tnature\tof\tthe\tmechanisms\tinvolved.\tThe
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nature\tof\tthe\tmechanisms\tinvolved.\tThe\nclinical\trelevance\tof\tadverse\treactions\tto\tfood\tshould\tbe\tcarefully\tassessed\tand\tevaluated\tusing\tthe\nnutrition\tcare\tprocess\t(\nFig.\t25.1\n).
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FIG.\t25.1\n\t\nAdverse\treactions\tto\tfood.\nCMPA\n,\tCow’s\tmilk\tprotein\tallergy;\t\nEGE\n,\teosinophilic\tgastroenteritis;\t\nEoE\n,\neosinophilic\tesophagitis;\t\nFDEIA\n,\tfood-dependent,\texercise-induced\tanaphylaxis;\t\nFODMAPs\n,\tfructo-,\toligo-,\tdi-,\nmonosaccharides,\tand\tpolyols\tsyndrome;\t\nFPIE\n,\tfood\tprotein–induced\tenteropathy;\t\nFPIES\n,\tfood\tprotein–induced
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,\tfood\tprotein–induced\tenteropathy;\t\nFPIES\n,\tfood\tprotein–induced\nenterocolitis\tsyndrome;\t\nFPIP\n,\tfood\tprotein–induced\tproctocolitis;\t\nIBD\n,\tinflammatory\tbowel\tdisease;\t\nMSUD\n,\tmaple\nsyrup\turine\tdisease;\t\nOAS\n,\toral\tallergy\tsyndrome;\t\nPKU\n,\tphenylketonuria.\nDefinitions\nAdverse\treactions\tto\tfood
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PKU\n,\tphenylketonuria.\nDefinitions\nAdverse\treactions\tto\tfood\n\tencompass\tfood\tallergies\tand\tfood\tintolerances,\tboth\tof\twhich\tcan\tinvolve\nmultiple\tsystems,\tcause\tdiverse\tsymptoms,\tand\tnegatively\timpact\thealth.\nFood\tallergy\n\tis\tdefined\tas\tan\tadverse\thealth\teffect\tarising\tfrom\ta\tspecific\timmune\tresponse\n\tthat
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that\noccurs\treproducibly\ton\texposure\tto\ta\tgiven\tfood.\tA\tfood\tis\tdefined\tas\t“any\tsubstance—whether\nprocessed,\tsemiprocessed,\tor\traw—that\tis\tintended\tfor\thuman\tconsumption,\tand\tincludes\tdrinks,\nchewing\tgum,\tfood\tadditives\tand\tdietary\tsupplements.”\tThe\tcomponents\twithin\tfoods\tthat\ttrigger
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immunologic\treactions\tare\tcalled\tantigens,\tand\tmost\toften\tare\tglycoproteins\tthat\tinteract\twith\timmune\ncells\tand\tinitiate\n\tthe\tdevelopment\tof\ta\tfood\tallergy\t(\nNational\tAcademies\tof\tSciences,\tEngineering,\tand\nMedicine\t[NASEM],\t2017\n).\nSymptoms\tcan\trange\tfrom\turticaria\tto\tlife-threatening\tanaphylaxis.\tFood\tallergy\telicits\treactions\tto
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foods\tthat\tinclude\tthe\tfollowing:\n•\t\nReactions\tthat\telicit\tproduction\tof\tspecific\timmunoglobulins\tsuch\tas\tIgE\n•\t\nReactions\tthat\tresult\tfrom\trelease\tof\tinflammatory\tmediators\tin\tresponse\n\tto\tIgE\tproduced\nagainst\tnonfood\tmaterials\tsuch\tas\tinhaled\tpollens\tor\tlatex\n•\t\nReactions\tthat\tresult\tfrom\tinflammatory\tmediators\treleased\tfrom\tgranulocytes\tsuch\tas
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eosinophils\tin\tthe\tdigestive\ttract\n•\t\nReactions\tthat\taffect\tthe\tdigestive\tsystem\t(enteropathies)\tdue\tto\tproteins\tin\tmilk\tor\tsoy\n•\t\nGastrointestinal\tdisorders\tsuch\tas\tceliac\tdisease\t(gluten\tsensitive\tenteropathy)\twhich\thas\tan\nimmune\tcomponent\nFood\tintolerance\tis\tan\tadverse\treaction\tto\ta\tfood\tor\tfood\tcomponent\tthat\tlacks\tan\tidentified
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immunologic\tpathophysiology.\tIt\tresults\tfrom\tthe\tbody’s\tinability\tto\tdigest,\tabsorb,\tor\tmetabolize\ta\tfood\nor\tcomponent\tof\tthe\tfood.\tThese\tnonimmune\tmediated\treactions\tare\tcaused\tby\tmetabolic,\ttoxicologic,\npharmacologic,\tmicrobial,\tand\tundefined\tmechanisms\t(\nSicherer\tand\tSampson,\t2018\n).\tFor\texample,\tan
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-0.10830140858888626, -0.05838768184185028, -0.015163974836468697, 0.04137369245290756, 0.0856110155582428, -0.035437360405921936, -0.03181154280900955, -0.003072985913604498, 0.0701749324798584, 0.005060138646513224, -0.012196301482617855, -0.09702852368354797, -0.07608550786972046, -0.04142154008150101, 0.011100049130618572, -0.00828635599464178, 0.023186352103948593, -0.02701512537896633, 0.09592464566230774, -0.010116979479789734, -0.06329406052827835, -0.03216497227549553, 0.013261545449495316, -0.05816476792097092, 0.015487844124436378, 0.033542778342962265, -0.08257392793893814, -0.13742101192474365, 0.06350923329591751, -0.005152557976543903, 0.03708338737487793, -0.028464147821068764, -0.04712306335568428, -0.012545987032353878, -0.0384419783949852, 0.014057733118534088, 0.02299814112484455, -0.024868223816156387, -0.03144753724336624, -0.014293991960585117, -0.02941548079252243, 0.012425810098648071, 0.04544219747185707, 0.04097740724682808, 0.006815049331635237, 0.04980405792593956, -0.009978147223591805, 0.057418789714574814, 0.09230135381221771, -4.730615188464071e-8, 0.06732553988695145, -0.026677124202251434, -0.00862440187484026, -0.021648522466421127, 0.007733340375125408, 0.013372434303164482, 0.03521580994129181, 0.026035919785499573, 0.027381988242268562, -0.07603543996810913, 0.00248141773045063, 0.10680276155471802, -0.05017830431461334, -0.021214863285422325, 0.0884520635008812, 0.01086525246500969, -0.07064130902290344, 0.03747663274407387, -0.05850715562701225, -0.08010471612215042, -0.027373066172003746, 0.042763255536556244, -0.04990679770708084, 0.01474349107593298, 0.024854004383087158, -0.014821216464042664, -0.026799730956554413, -0.004801470320671797, 0.02205895632505417, 0.017606200650334358, 0.04091021791100502, -0.03170938044786453, -0.016262125223875046, -0.035564158111810684, -0.03648177534341812, 0.044541776180267334, -0.020373467355966568, -0.06626733392477036, -0.058590054512023926, 0.0952983945608139, 0.01501303631812334, -0.025698022916913033, -0.05873908847570419, 0.062188394367694855, 0.03773288056254387, -0.05846567824482918, -0.009887602180242538, 0.11816249042749405, 0.006004949100315571, -0.07514476031064987, 0.0025343862362205982, 0.09278317540884018, 0.021263791248202324, -0.02869224175810814, -0.09021852165460587, 0.06165003776550293, 0.08490829169750214, 0.02676011063158512, 0.001298758783377707, -0.013796867802739143, 0.05717894434928894, 0.07145968079566956, 0.10315585881471634, -0.025561366230249405 ]
Sicherer\tand\tSampson,\t2018\n).\tFor\texample,\tan\nindividual\tcan\tbe\tintolerant\tto\tmilk\tbecause\tof\tan\tinability\tto\tdigest\tthe\tcarbohydrate\tlactose\tor\nintolerant\tto\thistamine-containing\tfoods\tdue\tto\tenzyme\tdeficiencies\tor\tother\tmechanisms\t(\nTable\t25.1\n).\nTABLE\t25.1\nSome\tExamples\tof\tFood\tIntolerances\nCause\nAssociated\tFood(s)\nSymptoms
[ -0.008347607217729092, -0.03992287442088127, 0.037064917385578156, 0.02135457843542099, -0.00772303668782115, -0.0025302604772150517, 0.0985051840543747, 0.02032501809298992, -0.04289786145091057, 0.04072247073054314, 0.11271218955516815, -0.06979449093341827, 0.03001110441982746, 0.02549789845943451, -0.020433036610484123, -0.008088143542408943, -0.01013957429677248, 0.01904231309890747, -0.04286029189825058, -0.01587417721748352, 0.04534333199262619, 0.10071859508752823, 0.0032572238706052303, 0.013554362580180168, -0.0163323525339365, 0.01707233302295208, -0.02669503726065159, -0.04641007259488106, -0.02644217386841774, -0.03216995298862457, -0.10059555619955063, 0.10006874054670334, -0.008065442554652691, -0.030033688992261887, 0.06794371455907822, 0.014824769459664822, -0.05917075276374817, -0.02022545225918293, 0.04506170377135277, 0.0028540201019495726, -0.04184707999229431, -0.08831574767827988, -0.0336930975317955, -0.00269621261395514, 0.05718790367245674, 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0.0479309968650341, -0.03993002325296402, -0.03923013061285019, -0.02484777569770813, -0.020703738555312157, 0.004869593307375908, -0.03765048831701279, 0.08511751890182495, -0.017627369612455368, 0.08398714661598206, 0.01485593244433403, -0.07306687533855438, 0.0035603176802396774, 0.002131251385435462, -0.16178381443023682, -0.0582582913339138, -0.00010099842620547861, -0.028260651975870132, -0.06305447965860367, 0.015720725059509277, 0.02668682113289833, 0.0780915915966034, 0.05998072400689125, -0.020146334543824196, 0.031232740730047226, -0.027999745681881905, 0.0009687953861430287, -0.0887518972158432, -0.03843773901462555, -0.05292673408985138, 0.04312900826334953, -0.010600055567920208, -0.09473089128732681, -0.02125595510005951, -0.00043294031638652086, -0.047091294080019, 0.021211765706539154, -0.012034032493829727, -0.02146349847316742, 0.03245724365115166, -0.027893496677279472, -0.05203278362751007, -0.07901286333799362, -3.8569824727501645e-33, -0.035494886338710785, 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0.035944584757089615, -0.021953875198960304, 0.09896516054868698, 0.10869266092777252, -4.484703453044858e-8, 0.046222005039453506, -0.06703458726406097, -0.04244255647063255, -0.0016713531222194433, 0.03565365821123123, 0.03819090127944946, 0.04389717057347298, 0.02541409060359001, -0.008380921557545662, -0.04298369958996773, -0.006455655675381422, 0.11192792654037476, -0.06334683299064636, -0.02550707757472992, 0.036290865391492844, 0.026768896728754044, -0.0169818215072155, 0.08351127058267593, -0.03423512354493141, -0.06622369587421417, -0.033476151525974274, 0.060922812670469284, -0.013226346112787724, -0.00035349829704500735, 0.014836995862424374, -0.032652705907821655, -0.014408808201551437, 0.023334376513957977, 0.059363313019275665, 0.0560770258307457, 0.04231695085763931, -0.051509398967027664, -0.01857999712228775, -0.018731242045760155, 0.01120311114937067, 0.054649222642183304, -0.07915488630533218, -0.004711111541837454, -0.04234174266457558, 0.0978749692440033, -0.06007084622979164, -0.008685455657541752, -0.06702296435832977, 0.07766645401716232, 0.07512853294610977, -0.084089495241642, -0.018279045820236206, 0.10916853696107864, -0.0002979423152282834, -0.07604196667671204, 0.021021122112870216, 0.09391741454601288, 0.0060286009684205055, 0.00733124278485775, -0.07935203611850739, 0.032263826578855515, 0.10482792556285858, 0.022432459518313408, 0.014366023242473602, -0.022641653195023537, 0.03852386772632599, 0.06302919238805771, 0.07818065583705902, 0.00027565661002881825 ]
Some\tExamples\tof\tFood\tIntolerances\nCause\nAssociated\tFood(s)\nSymptoms\nGastrointestinal\tDisorders\nEnzyme\tDeficiencies\nLactose\nintolerance\n(lactase\ndeficiency)\nFoods\tcontaining\tlactose\tand\tmammalian\tmilk\nBloating,\tflatulence,\ndiarrhea,\tabdominal\npain\nGlucose-6\nphosphate\ndehydrogenase\nFava\tor\tbroad\tbeans\nHemolytic\tanemia
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deficiency\nFructose\nintolerance\nFoods\tcontaining\tfructose\tor\tsucrose\nBloating,\tflatulence,\ndiarrhea,\tabdominal\npain\nFODMAPs\nintolerance\nFoods\tcontaining\tfructo-,\toligo-,\tdi-,\tand\tmonosaccharides\nand\tpolyols\nBloating,\tflatulence,\ndiarrhea,\tcramping,\nabdominal\tpain\nDiseases\nCystic\tfibrosis\nSymptoms\tmay\tbe\tprecipitated\tby\tmany\tfoods,\tespecially
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0.03326255455613136, -0.045312073081731796, 0.019736815243959427, 0.12197302281856537, -4.420547838890343e-8, 0.09229207038879395, -0.07020854949951172, -0.04009582847356796, -0.011697854846715927, 0.0595829077064991, -0.021588433533906937, -0.0014728610403835773, 0.047057583928108215, 0.07852312922477722, 0.015748407691717148, -0.07090336829423904, 0.1567818820476532, -0.06864466518163681, 0.0003773586358875036, 0.06793399155139923, 0.0358499214053154, -0.027287065982818604, 0.05570723116397858, 0.00967707671225071, -0.013850661925971508, -0.12725931406021118, -0.004825994372367859, -0.01931002549827099, 0.005758566781878471, 0.018503472208976746, -0.0350760780274868, 0.022213896736502647, 0.017137087881565094, 0.07226211577653885, 0.03394942358136177, 0.10442692041397095, -0.032536499202251434, -0.028693119063973427, -0.061633456498384476, 0.01887536235153675, 0.014488426968455315, -0.0751705914735794, -0.04702504351735115, -0.06399417668581009, 0.001221143058501184, -0.019498763605952263, -0.015694571658968925, -0.05979824438691139, 0.03227894380688667, 0.0336265005171299, -0.06225299835205078, -0.02625727467238903, 0.090981625020504, 0.03981376066803932, -0.07433667778968811, -0.01889675483107567, 0.02821737341582775, 0.009251457639038563, -0.0028951705899089575, -0.01191527210175991, 0.030159305781126022, 0.13001379370689392, -0.01630178466439247, 0.027779946103692055, -0.0005444739363156259, 0.030941208824515343, 0.11096373200416565, 0.08375708758831024, -0.020233726128935814 ]
Symptoms\tmay\tbe\tprecipitated\tby\tmany\tfoods,\tespecially\nhigh-fat\tfoods\nBloating,\tloose\tstools,\nabdominal\tpain,\nmalabsorption\nGallbladder\ndisease\nSymptoms\tmay\tbe\tprecipitated\tby\thigh-fat\n\tfoods\nAbdominal\tpain\tafter\neating\nPancreatic\ndisease\nInflammatory\nbowel\tdisease\nSymptoms\tmay\tbe\tprecipitated\tby\teating\nAnorexia,\tnausea,\ndysgeusia,\tand\tother
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0.05786188319325447, -0.11822643876075745, -0.04067712277173996, -0.02083691582083702, -0.015464706346392632, 0.043681420385837555, -0.0060457936488091946, 0.08880771696567535, 0.05160742625594139, 0.07850772887468338, 0.014559200964868069, -0.052609626203775406, -0.038677915930747986, -0.0027052711229771376, -0.15416787564754486, -0.06000319868326187, -0.06381845474243164, 0.06357265263795853, -0.048640456050634384, 0.03295738622546196, 0.031682901084423065, 0.026674527674913406, 0.097353495657444, 0.021661367267370224, 0.01131938025355339, -0.06039263308048248, -0.023215292021632195, -0.06910847872495651, -0.06173627823591232, -0.049806877970695496, 0.04223715886473656, 0.04617687314748764, -0.05154624581336975, 0.003337169997394085, -0.06669529527425766, -0.01969160884618759, 0.009982682764530182, -0.02407524362206459, -0.046732768416404724, 0.06658659130334854, -0.060253117233514786, -0.007585599087178707, -0.0580008402466774, -5.866873570512821e-33, -0.0166759192943573, 0.022546524181962013, -0.013351024128496647, 0.02516760863363743, -0.04931003227829933, 0.006945634260773659, 0.010765102691948414, 0.07069744914770126, 0.1011214405298233, -0.040792983025312424, 0.03546087071299553, 0.013982624746859074, -0.10042320191860199, -0.1149749681353569, -0.07726500928401947, 0.11999226361513138, 0.03378894180059433, 0.0867600291967392, 0.00896094273775816, -0.009276328608393669, -0.12678340077400208, 0.009818143211305141, -0.04384367913007736, 0.0441252626478672, 0.0051651811227202415, 0.09703701734542847, 0.07419968396425247, -0.04408222436904907, 0.0068983640521764755, 0.004256612621247768, 0.06037752702832222, -0.008653609082102776, 0.016282327473163605, 0.00148959259968251, -0.027523262426257133, -0.004856851417571306, -0.0654815286397934, -0.061942942440509796, -0.004916427191346884, 0.004677241202443838, 0.05491793900728226, -0.033888399600982666, 0.05794842913746834, 0.022928066551685333, 0.019618257880210876, -0.01626681163907051, 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0.06822824478149414, -0.025186751037836075, 0.02877068892121315, 0.07199510931968689, -4.688324750645734e-8, 0.08056514710187912, -0.06346528232097626, 0.007967186160385609, 0.0006445145118050277, 0.02346530370414257, -0.047911763191223145, 0.022470548748970032, 0.07093776762485504, 0.046615563333034515, -0.0004748887731693685, -0.06388595700263977, 0.14629805088043213, -0.1082417219877243, -0.0426061786711216, 0.02452823519706726, 0.020874209702014923, -0.025934724137187004, 0.07850922644138336, -0.013705373741686344, -0.08295781910419464, -0.10173012316226959, 0.005689887795597315, -0.0027042203582823277, 0.013905392959713936, 0.03655940666794777, -0.0019658938981592655, 0.00217748386785388, -0.005950457416474819, 0.031355567276477814, 0.058253441005945206, 0.1056545078754425, -0.03724461793899536, -0.06121505796909332, -0.01647314429283142, 0.02923625148832798, 0.00867974292486906, -0.053412605077028275, -0.023047087714076042, -0.02227860316634178, 0.08931533992290497, -0.02132323384284973, -0.0420321561396122, 0.02973782829940319, 0.04801914840936661, 0.04574792459607124, -0.06384585797786713, -0.030716119334101677, 0.08834268897771835, 0.07694388180971146, -0.060611333698034286, 0.004739101976156235, 0.024626297876238823, 0.03589329123497009, 0.01464469451457262, -0.040411315858364105, 0.05577148124575615, 0.10985542088747025, -0.004682461731135845, 0.03266678377985954, 0.0385921485722065, 0.06870553642511368, 0.11013886332511902, 0.08040274679660797, 0.007296036928892136 ]
Anorexia,\tnausea,\ndysgeusia,\tand\tother\ngastrointestinal\nsymptoms\nInborn\tErrors\tof\tMetabolism\nPhenylketonuria\nFoods\tcontaining\tphenylalanine\nElevated\tserum\nphenylalanine\tlevels,\nmental\tretardation\nGalactosemia\nFoods\tcontaining\tlactose\tor\tgalactose\nVomiting,\tlethargy,\nfailure\tto\tthrive\nPsychological\tor\tNeurologic\tReactions\nPsychological\tor
[ 0.041704121977090836, -0.07228253036737442, -0.012054628692567348, 0.04816577956080437, -0.10691751539707184, -0.009575441479682922, 0.055333711206912994, 0.02919287420809269, -0.10656451433897018, 0.05737261846661568, 0.106050506234169, -0.03424236550927162, 0.017044343054294586, 0.01698814332485199, -0.05116206035017967, 0.008730362169444561, 0.01635279878973961, 0.0035570154432207346, -0.00024157098960131407, 0.03193290904164314, 0.052690234035253525, 0.11315222084522247, 0.06413417309522629, -0.025781260803341866, -0.007995435036718845, -0.07597658038139343, -0.02700120396912098, -0.07139050960540771, -0.021751046180725098, -0.008620113134384155, -0.12356438487768173, 0.04123186320066452, -0.001831656671129167, 0.03877701610326767, 0.043394625186920166, -0.024878354743123055, -0.007971311919391155, -0.006875946186482906, 0.04611801356077194, 0.009164123795926571, 0.00298694777302444, -0.0683290883898735, -0.04263187199831009, 0.04698958247900009, -0.061207834631204605, 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Psychological\tor\tNeurologic\tReactions\nPsychological\tor\nneurologic\ndisorder\nSymptoms\tmay\tbe\tprecipitated\tby\tany\tfood\nWide\tvariety\tof\nsymptoms\tinvolving\nany\tsystem\nReactions\tto\tPharmacologic\tAgents\tin\tFoods\nPhenylethylamine\nChocolate,\taged\tcheeses,\tred\twine\nMigraine\theadaches\nTyramine\nAged\tcheeses,\tbrewer’s\tyeast,\tred\twine,\tcanned\tfish,
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Tyramine\nAged\tcheeses,\tbrewer’s\tyeast,\tred\twine,\tcanned\tfish,\nchicken\tliver,\tbananas,\n\teggplant,\ttomatoes,\traspberries,\nplums\nMigraine\theadaches,\ncutaneous\terythema,\nurticaria,\tand\nhypertensive\tcrisis\tin\npatients\ttaking\nmonoamine\toxidase\ninhibitors\t(MAOIs)\nHistamine\tand\nhistamine\nreleasing\tagents
[ 0.007835017517209053, -0.09351994842290878, -0.013563166372478008, -0.034392718225717545, -0.05028587579727173, 0.03470440208911896, 0.07491817325353622, 0.08849277347326279, -0.028059417381882668, 0.10140082985162735, 0.09559366106987, -0.04491525515913963, 0.04261065274477005, 0.028826255351305008, -0.034028246998786926, 0.0789010301232338, -0.020422497764229774, -0.04492893069982529, 0.010093721561133862, 0.00820648018270731, -0.0012254572939127684, 0.13229764997959137, 0.017285490408539772, -0.01943502202630043, 0.0036299689672887325, 0.05203910917043686, -0.021973473951220512, -0.046666719019412994, -0.03608715161681175, -0.05441652610898018, -0.08038013428449631, 0.04772421717643738, 0.0018981964094564319, -0.010860618203878403, 0.037666745483875275, -0.01240652333945036, -0.08969823271036148, 0.0037356156390160322, 0.08134032040834427, 0.03827507421374321, 0.0475446991622448, -0.02173025906085968, -0.05793815106153488, 0.004744764883071184, -0.02633841335773468, -0.01773970015347004, 0.020670291036367416, -0.04683859646320343, 0.023346522822976112, -0.012821171432733536, -0.004491702653467655, -0.06703542172908783, -0.06424760818481445, 0.10643000155687332, -0.020198658108711243, -0.05290071293711662, -0.06193825602531433, -0.027294257655739784, -0.03793804720044136, 0.04652296379208565, -0.020277949050068855, 0.004181274678558111, 0.025117486715316772, -0.03524487465620041, -0.003542800433933735, 0.025750339031219482, -0.007835041731595993, 0.00840130727738142, 0.025391822680830956, 0.06528636068105698, -0.008582177571952343, 0.004294322803616524, 0.027671704068779945, 0.06962408870458603, -0.07349532097578049, 0.029645007103681564, 0.09292305260896683, -0.052792131900787354, 0.009607440792024136, -0.04241451621055603, -0.15213166177272797, 0.08336429297924042, 0.032007232308387756, 0.05243648588657379, 0.020247919484972954, 0.023760206997394562, -0.018019409850239754, 0.09011474251747131, -0.008562094531953335, 0.036636169999837875, -0.00009518815932096913, -0.025885125622153282, 0.03393201902508736, -0.005815326236188412, -0.05833493545651436, -0.040501873940229416, 0.05121924355626106, -0.024931667372584343, 0.013531102798879147, -0.05159367620944977, 0.003382514463737607, -0.03809833526611328, -0.016558438539505005, -0.015806570649147034, -0.06254159659147263, 0.003514071460813284, -0.00812261737883091, -0.07854955643415451, 0.025203226134181023, -0.0033400373067706823, -0.04002407565712929, -0.0004599994863383472, 0.056448906660079956, -0.046031635254621506, -0.007869566790759563, -0.02723652683198452, -0.00012369168689474463, -0.010211994871497154, 0.07811896502971649, 0.003862688783556223, 0.020182998850941658, -0.051869459450244904, 0.09316578507423401, 0.036800798028707504, -0.05979738384485245, 0.0072477273643016815, -0.013532702811062336, 8.233756608819444e-34, 0.06182357296347618, 0.0611313134431839, -0.009166160598397255, 0.04015712812542915, 0.04510999470949173, 0.029930878430604935, -0.05598757416009903, -0.032976094633340836, 0.01242197584360838, 0.028827019035816193, -0.10909832268953323, 0.01323222741484642, 0.03141934052109718, 0.10794822126626968, -0.012219793163239956, -0.058527249842882156, -0.027517743408679962, 0.016156895086169243, 0.018521226942539215, -0.055991269648075104, -0.06161608546972275, 0.15296217799186707, -0.0034686748404055834, 0.022018615156412125, -0.11087726801633835, 0.004564346745610237, -0.040004339069128036, -0.006123773753643036, 0.046824630349874496, -0.009901321493089199, 0.029952505603432655, -0.07137347757816315, -0.007644159719347954, 0.02554805390536785, -0.008092451840639114, 0.05094119533896446, -0.028531212359666824, 0.03969355300068855, -0.054564423859119415, -0.006077249068766832, -0.004776470363140106, 0.02048039622604847, 0.0009967320365831256, 0.05576993152499199, 0.05421501398086548, -0.043078240007162094, -0.06604251265525818, 0.00015372307098004967, 0.02237745001912117, -0.04998522624373436, 0.0004062351945322007, -0.04222414270043373, 0.09286566078662872, -0.023607634007930756, -0.05211885645985603, -0.008291956037282944, -0.04828105494379997, 0.02254951000213623, 0.0046758526004850864, 0.08366797119379044, 0.03690845146775246, 0.017507191747426987, -0.0001978651707759127, -0.011507545597851276, -0.003667484736070037, 0.023612579330801964, -0.12891162931919098, -0.07021026313304901, -0.011906665749847889, -0.0011474201455712318, -0.04802890121936798, -0.004865167662501335, 0.04916547238826752, 0.050546083599328995, 0.07226614654064178, 0.015875812619924545, -0.010301881469786167, -0.04676800221204758, -0.05164919048547745, -0.02542351931333542, -0.06032075732946396, -0.1145123615860939, -0.007688980083912611, -0.0013892508577555418, -0.06862512230873108, -0.009626410901546478, 0.011654787696897984, -0.058857511729002, 0.01719730533659458, 0.025540268048644066, -0.04794573038816452, -0.0021153816487640142, -0.034158188849687576, -0.06929511576890945, -0.08855672180652618, -1.860902147912724e-33, -0.034658096730709076, -0.040142472833395004, -0.037236034870147705, -0.03476918488740921, -0.008245894685387611, 0.033255863934755325, 0.0019536600448191166, 0.04708871245384216, 0.02842227928340435, -0.05408298969268799, 0.09792737662792206, 0.004920001607388258, -0.06241858750581741, -0.11279520392417908, -0.08206143230199814, 0.0011672761756926775, 0.036647893488407135, 0.12195106595754623, -0.003958156332373619, -0.07167994230985641, -0.13046006858348846, 0.03700006753206253, -0.1113024577498436, 0.028884172439575195, 0.08412228524684906, 0.09454433619976044, -0.017276160418987274, -0.030546924099326134, 0.03832361474633217, 0.0709756463766098, 0.021303609013557434, 0.028691954910755157, -0.0001961202797247097, 0.04059518873691559, 0.01953171007335186, 0.027353569865226746, 0.022341493517160416, -0.12358740717172623, -0.011392064392566681, -0.03456040099263191, 0.016160259023308754, -0.009617939591407776, 0.12008022516965866, 0.04039736092090607, 0.04174651578068733, 0.04321560636162758, -0.14539535343647003, -0.03345808386802673, -0.08160099387168884, 0.0776161476969719, 0.05323106423020363, -0.01991373859345913, -0.038728129118680954, -0.05905178561806679, 0.08407790213823318, -0.03431900963187218, -0.023460298776626587, -0.07234185934066772, 0.02090832218527794, -0.04044421762228012, 0.009722557850182056, -0.02689196728169918, 0.008657116442918777, 0.007256154902279377, 0.017825918272137642, -0.04891413822770119, -0.07058748602867126, 0.020415959879755974, 0.02928064577281475, -0.024990346282720566, 0.03281440585851669, 0.05141032487154007, -0.02746833860874176, -0.06998781114816666, 0.049341052770614624, -0.07133416086435318, 0.015582426451146603, -0.029738586395978928, 0.028933627530932426, -0.06434973329305649, -0.010479782707989216, 0.0015359640819951892, 0.02788328006863594, -0.034955017268657684, 0.00343207991681993, 0.008860464207828045, -0.011687546037137508, 0.06686653941869736, 0.02458227053284645, 0.01811770349740982, 0.007893582805991173, -0.028812622651457787, -0.037235550582408905, 0.0734323114156723, 0.10011985152959824, -4.58197106922853e-8, 0.1002378761768341, -0.03987519070506096, 0.006304015871137381, -0.029816094785928726, 0.010496162809431553, 0.01043915655463934, 0.033762965351343155, 0.06348984688520432, 0.03698322921991348, -0.04530927166342735, 0.025057634338736534, 0.11192459613084793, -0.05507544055581093, -0.029534386470913887, 0.04376692324876785, -0.0006395029486157, -0.004859280772507191, 0.07343259453773499, -0.02112772688269615, -0.06884951889514923, -0.06833253800868988, 0.07842016220092773, -0.052266839891672134, -0.013073485344648361, 0.022329922765493393, -0.023394880816340446, -0.023726189509034157, -0.01193657610565424, 0.030421435832977295, 0.004858642816543579, 0.046079766005277634, -0.012644103728234768, -0.005417414475232363, -0.093661829829216, 0.003137855092063546, 0.07775426656007767, 0.006627839989960194, -0.06488680839538574, -0.01827760972082615, 0.06752456724643707, -0.03793632239103317, -0.03770558163523674, -0.055242881178855896, 0.015170184895396233, 0.059430357068777084, -0.06593745201826096, -0.01475372165441513, 0.12688280642032623, 0.02486017718911171, -0.11461266130208969, 0.007574221584945917, 0.08459558337926865, 0.03922588750720024, -0.05787839740514755, -0.10525046288967133, 0.03266124799847603, 0.05831937491893768, -0.012215782888233662, -0.005501506384462118, -0.06259193271398544, 0.053771574050188065, 0.07785636186599731, 0.11380230635404587, 0.030345864593982697 ]
inhibitors\t(MAOIs)\nHistamine\tand\nhistamine\nreleasing\tagents\nAged\tcheeses,\tfermented\tfoods\t(e.g.,\tsauerkraut,\tyogurt,\nkefir),\tprocessed\tmeats\t(e.g.,\tsausage,\tbologna,\tsalami),\ncanned\tand\tsmoked\tfish,\tred\tbeans,\tsoybeans,\tcitrus,\navocado,\teggplant,\n\tolives,\ttomatoes\tand\ttomato\tproducts,\nchocolate,\tcocoa,\ttea,\tyeast,\tmany\tspices,\tmany\tfood
[ 0.005088297184556723, -0.06395839154720306, -0.05526532232761383, -0.01960168033838272, 0.014651015400886536, 0.053112633526325226, 0.05862009897828102, 0.10851779580116272, 0.037134844809770584, 0.07176186889410019, 0.10702046006917953, -0.028801104053854942, 0.041257087141275406, 0.03422049432992935, -0.02941075526177883, 0.047618620097637177, -0.006768032908439636, 0.01952606998383999, -0.021335961297154427, -0.038287289440631866, 0.029846947640180588, 0.11105324327945709, 0.022296739742159843, 0.01695512980222702, -0.04063422605395317, 0.02109265699982643, -0.03125142306089401, -0.06452538818120956, -0.002265145070850849, -0.050895459949970245, -0.07895012944936752, 0.04851744323968887, 0.0633239820599556, 0.0009467657073400915, -0.0012610087869688869, 0.02126607485115528, -0.11138948798179626, -0.009520702064037323, 0.0646231546998024, 0.035093024373054504, 0.0724509134888649, -0.05216648802161217, -0.05885943025350571, -0.04678446054458618, 0.05400818586349487, -0.07733042538166046, 0.023570390418171883, -0.04450835660099983, -0.003426844486966729, 0.01801665686070919, -0.07416588813066483, -0.026905091479420662, -0.055780235677957535, 0.10377098619937897, -0.02887277863919735, -0.025290295481681824, -0.037000302225351334, 0.009077954106032848, -0.000021532501705223694, 0.04179024696350098, 0.012370235286653042, 0.0037527268286794424, 0.0007825678330846131, -0.024239860475063324, 0.009327531792223454, 0.04205823689699173, -0.014644420705735683, 0.011838657781481743, 0.006509647238999605, 0.018569236621260643, -0.020985685288906097, -0.05368832126259804, 0.0006697411881759763, 0.05021398141980171, -0.03777970001101494, 0.05434226617217064, 0.05814303457736969, -0.024842271581292152, 0.003378496738150716, -0.06655903905630112, -0.06683668494224548, 0.08174356818199158, 0.05494292080402374, 0.05016178637742996, 0.02481820248067379, 0.032402269542217255, -0.014270628802478313, 0.09391383826732635, 0.09289991855621338, 0.06158618628978729, 0.04454359784722328, -0.012527329847216606, -0.01654440350830555, -0.03085995279252529, -0.0337010994553566, -0.06563445925712585, 0.01340652909129858, -0.02497563138604164, -0.020917491987347603, -0.05588258430361748, 0.011845771223306656, -0.0211139228194952, -0.061113402247428894, -0.06529581546783447, -0.07297120243310928, 0.0002840355737134814, 0.04094729572534561, -0.06974007934331894, 0.07223851978778839, 0.016735399141907692, -0.08129935711622238, -0.015280728228390217, 0.047920577228069305, -0.015824273228645325, 0.004085935186594725, -0.03610778972506523, 0.007461208384484053, -0.03950819373130798, 0.07658039033412933, 0.007377800066024065, 0.07003951817750931, -0.05883152037858963, 0.06490512192249298, 0.03568173944950104, -0.028100743889808655, -0.020099714398384094, -0.02750418148934841, -2.1708065398276347e-34, 0.033945612609386444, 0.0639781728386879, -0.014900500886142254, 0.07263610512018204, 0.06764911860227585, 0.006921227090060711, -0.04823863506317139, 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chocolate,\tcocoa,\ttea,\tyeast,\tmany\tspices,\tmany\tfood\nadditives\tand\tpreservatives,\tshellfish,\tegg\twhites,\navocado,\tstrawberries,\tpineapple,\tspinach,\tnuts,\tpeanuts,\nalcohol\nDizziness,\tflushing,\nhives,\terythema,\nrunny\tnose,\nheadaches,\tdecreased\nblood\tpressure,\nnausea,\tvomiting,\nshortness\tof\tbreath,\nedema,\turticaria,\neczema,\tpruritus
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shortness\tof\tbreath,\nedema,\turticaria,\neczema,\tpruritus\nReactions\tto\tFood\tAdditives\nArtificial\tcolors:\ntartrazine\tor\nFD&C\tyellow\n#5\tand\tother\nazo\tdyes\nArtificially\tcolored\tyellow\tor\tyellow-orange\tfoods,\tsoft\ndrinks,\tsome\tmedicines\nHives,\trash,\tasthma,\nnausea,\theadaches\nBenzoates:\nbenzoic\tacid\tor\nsodium\nbenzoate
[ -0.0062141381204128265, -0.05496067553758621, 0.042462680488824844, -0.007603270001709461, -0.05070587620139122, 0.033432818949222565, 0.09165674448013306, 0.011164069175720215, -0.01602189987897873, 0.06029590964317322, 0.0882101058959961, -0.011830898933112621, 0.023628374561667442, 0.04837276414036751, -0.020238401368260384, 0.010926105082035065, 0.0024711855221539736, 0.03970428556203842, -0.07584452629089355, -0.018226169049739838, 0.06107570603489876, 0.10457492619752884, 0.0821220651268959, 0.01208658330142498, -0.0017358302138745785, 0.05641784518957138, -0.03394266217947006, 0.007117945235222578, 0.0019238961394876242, -0.06779735535383224, -0.05949433147907257, 0.06789888441562653, 0.042625490576028824, -0.010502425953745842, 0.04399682208895683, 0.031451523303985596, -0.06743808090686798, 0.0031652378384023905, 0.08889012783765793, 0.04604010283946991, -0.004648222122341394, -0.04117581248283386, -0.03785135596990585, 0.05638730153441429, 0.035717107355594635, 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nausea,\theadaches\nBenzoates:\nbenzoic\tacid\tor\nsodium\nbenzoate\nProcessed\tfoods\tas\tantimicrobial\tpreservatives;\tcolor\npreservatives;\tbleaching\tagents\nNaturally\toccurring\tin\tberries,\tcinnamon\tand\tother\tspices,\ntea\nDishes\twith\n\tspicy\tsauces\tand\tcurry\tpowder,\tavocado,\tdried\nfruits,\tsome\tcarbonated\tdrinks,\talcoholic\tmixers,\tmilk
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-0.044091854244470596, -0.07284123450517654, -0.0012336390791460872, 0.002476082881912589, -0.08892744034528732, 0.00020002873498015106, 0.05804682895541191, 0.027660630643367767, -0.07584886252880096, -0.028668945655226707, 0.08148053288459778, 0.019724776968359947, 0.022352976724505424, 0.011308723129332066, 0.02030111849308014, 0.0914018452167511, -0.0003140496264677495, 0.03400879725813866, -0.046224284917116165, 0.01760253682732582, 0.04638590291142464, 0.042286865413188934, 0.0053886729292571545 ]
fruits,\tsome\tcarbonated\tdrinks,\talcoholic\tmixers,\tmilk\nshake\tsyrup,\tsome\tcanned\tfoods\tlike\tbeans,\tflavored\nchips,\tsalad\tdressing\nHives,\trash,\tasthma,\nangioedema,\tnasal\ncongestion,\theadache,\ncontact\tdermatitis,\ndiverse\tdigestive\ttract\nsymptoms\nButylated\nhydroxyanisole\n(BHA);\nbutylated\nhydroxytoluene\n(BHT)\nProcessed\tfoods:\tused\tas\tantioxidants;
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-0.054910533130168915, -0.0669902041554451, 0.00211670296266675, 0.04524887353181839, -0.057910483330488205, -0.08232805132865906, 0.0883227214217186, 0.02043948881328106, -0.06801813095808029, 0.023934274911880493, 0.06533358246088028, 0.0034685195423662663, -0.0017994308145716786, -0.054555755108594894, 0.0019338402198627591, 0.08074427396059036, -0.04673168063163757, 0.037684500217437744, -0.01838061958551407, 0.0787394642829895, 0.09724904596805573, 0.13782420754432678, 0.05916478857398033 ]
butylated\nhydroxytoluene\n(BHT)\nProcessed\tfoods:\tused\tas\tantioxidants;\n\talso\tused\tin\tfood\npackaging\tmaterials\nSkin\treactions\tsuch\tas\nhives\nMonosodium\nglutamate\n(MSG)\nProcessed\tfoods\t(canned\tfoods,\tchips,\tgravy,\tflavor\tpackets\nfor\tinstant\tsoups,\tetc.)\tadded\tas\ta\tflavor\tenhancer;\toften\nused\tin\tAsian\tcuisine.\tNaturally\toccurring\tglutamic\tacid
[ -0.037817709147930145, -0.07282429188489914, 0.03751783445477486, -0.005971550475805998, -0.0582013763487339, 0.003951861523091793, 0.08929747343063354, 0.011280116625130177, -0.0020690166857093573, 0.021773405373096466, 0.1431548297405243, -0.05671156570315361, 0.06337368488311768, -0.016242079436779022, -0.033396702259778976, 0.01284292433410883, 0.04989151284098625, 0.006747008766978979, -0.09635130316019058, -0.01202069129794836, 0.07322441786527634, 0.08242208510637283, 0.02584405243396759, -0.010571179911494255, 0.05416063591837883, 0.06079532578587532, -0.03243296965956688, -0.0460500493645668, 0.04181170091032982, -0.05484935641288757, -0.05150245875120163, 0.05715835839509964, 0.001088939025066793, 0.012019774876534939, 0.06527845561504364, 0.04748024418950081, -0.05914989113807678, -0.026412148028612137, 0.044017329812049866, -0.020772848278284073, -0.030893515795469284, -0.06284526735544205, -0.04058244451880455, -0.009015554562211037, 0.009822087362408638, 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used\tin\tAsian\tcuisine.\tNaturally\toccurring\tglutamic\tacid\nis\tfound\tin\taged\tcheeses\tlike\tParmesan,\tfish\tsauce,\nmushrooms,\tspinach,\tmarmite\nFacial\tnumbness,\ntingling\tand\nnumbness\tin\n\thands\nand\tfeet,\tdizziness,\nbalance\tproblems,\nvisual\tdisturbances,\nheadaches,\tasthma,\nflushing,\tdiverse\ndigestive\ttract\nsymptoms
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Nitrates\tand\nnitrites\nProcessed\tfoods\tcontaining\tsodium\tnitrite,\tsodium\tnitrate,\npotassium\tnitrite\tand\tpotassium\tnitrate;\tcommonly\tfound\nin\tcured\tmeats,\tcanned\tmeats,\tsmoked\tfish,\tpate,\tpickled\nmeats\nFlushing,\thives,\nmigraine,\tother\nheadaches,\tdigestive\ntract\tsymptoms\nSalicylates\nNaturally\toccurring\tin\ta\tvariety\tof\tfruits,\tvegetables,\tand\nspices
[ 0.02388998121023178, -0.07288682460784912, 0.012372787110507488, 0.011808037757873535, -0.03656885027885437, -0.019258182495832443, 0.10144270211458206, -0.0021986933425068855, -0.03659329190850258, 0.02218177355825901, 0.08657623827457428, -0.08607538789510727, 0.01439188327640295, 0.00965366791933775, -0.059738922864198685, -0.012934400700032711, 0.053627364337444305, -0.006284301169216633, -0.04323004186153412, -0.010095927864313126, 0.028939753770828247, 0.10461714118719101, 0.004247063305228949, -0.021744590252637863, 0.010949932970106602, 0.028608929365873337, -0.04049786925315857, -0.047089602798223495, -0.00484631210565567, -0.07727213203907013, -0.05455872043967247, 0.06655814498662949, 0.04015036299824715, -0.052016790956258774, 0.07738617807626724, 0.0021980321034789085, -0.04616301506757736, 0.010645902715623379, 0.036491382867097855, 0.0329410545527935, 0.009878060780465603, -0.05687874183058739, -0.02565179392695427, 0.04222117364406586, -0.014551255851984024, 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0.07634307444095612, -0.013353058136999607, -0.06438996642827988, -0.010201646015048027, -0.022726593539118767, 0.03223206102848053, -0.04200460761785507, 0.03584861382842064, -0.04217132180929184, 0.07126019895076752, 0.01897175796329975, -0.007713564205914736, -0.0018549223896116018, 0.014513780362904072, -0.17423896491527557, -0.027515893802046776, 0.03509062901139259, -0.002750992076471448, -0.09470892697572708, 0.04612364247441292, 0.01923535391688347, 0.04090394824743271, 0.05311960354447365, -0.019567150622606277, 0.026493726298213005, -0.09665772318840027, -0.012246988713741302, -0.05059876665472984, 0.007883187383413315, -0.08687156438827515, 0.0013962473021820188, -0.051952190697193146, -0.08426808565855026, 0.010527899488806725, -0.019689060747623444, -0.0211567971855402, 0.07850876450538635, -0.036033518612384796, -0.0015486035263165832, -0.0091696847230196, -0.0105064632371068, -0.12393643707036972, -0.07398760318756104, -2.1454123721010193e-33, 0.0046516889706254005, 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0.012918036431074142, -0.00015675833856221288, 0.03407977148890495, 0.12838062644004822, -4.211205251181127e-8, 0.08322344720363617, -0.05221106857061386, -0.04242301359772682, 0.024146150797605515, 0.034958548843860626, -0.012108638882637024, 0.07804351300001144, 0.04039812088012695, 0.007022649981081486, -0.03414628654718399, 0.03179491311311722, 0.1210579201579094, -0.06035685911774635, -0.04111986607313156, 0.0981222465634346, 0.018970618024468422, 0.015530731528997421, 0.029771853238344193, -0.03809446841478348, -0.05617128685116768, -0.07346612960100174, 0.025177164003252983, -0.08074375241994858, -0.007984593510627747, -0.00859955046325922, -0.049435339868068695, 0.002965319436043501, -0.021780310198664665, 0.06466757506132126, 0.03797663003206253, 0.045229602605104446, -0.04522361978888512, 0.00019739587150979787, -0.06471669673919678, 0.009855699725449085, 0.05011142045259476, -0.05840428173542023, -0.0009787697345018387, 0.004946770612150431, 0.04684504121541977, -0.08541921526193619, -0.030554108321666718, -0.05451100692152977, 0.036789704114198685, 0.03442627936601639, -0.07474107295274734, -0.0514245480298996, 0.08971115946769714, 0.02502446062862873, -0.03293313458561897, -0.06089962273836136, 0.08226615190505981, -0.0032807490788400173, -0.008897937834262848, -0.010286016389727592, 0.038221441209316254, 0.10547161102294922, -0.016243785619735718, -0.03800688311457634, -0.015139038674533367, 0.03939365595579147, 0.055274877697229385, 0.09240717440843582, 0.014432811178267002 ]
Naturally\toccurring\tin\ta\tvariety\tof\tfruits,\tvegetables,\tand\nspices\nAngioedema,\tasthma,\nhives;\tpeople\nsensitive\tto\taspirin\tat\nhigher\trisk\tfor\ndeveloping\nintolerance\nSulfites\nSodium\tsulfite,\npotassium\nsulfite,\tsodium\nmetabisulfite,\npotassium\nmetabisulfite,\nsodium\tbisulfite,\npotassium\nbisulfite,\tsulfur\ndioxide
[ 0.011963116005063057, -0.03524868190288544, 0.062307070940732956, 0.0063981786370277405, -0.06943682581186295, -0.01450551301240921, 0.04633241519331932, -0.034671224653720856, -0.04272068291902542, 0.09435292333364487, 0.05126681923866272, -0.08243893086910248, -0.032794512808322906, -0.005690050311386585, -0.014094725251197815, 0.062124427407979965, -0.00776310870423913, 0.06609801948070526, -0.04161055013537407, 0.05330363288521767, 0.09317585080862045, 0.05215771496295929, 0.0008088547619991004, 0.008056608028709888, 0.03800489380955696, 0.08974647521972656, -0.0538589209318161, -0.006654177326709032, 0.030247250571846962, -0.03301095589995384, -0.0852055549621582, 0.027587372809648514, 0.009816879406571388, -0.011608409695327282, -0.008516654372215271, 0.05304649844765663, -0.05036007985472679, 0.027195917442440987, 0.03885750100016594, -0.018045807257294655, -0.015730980783700943, 0.009158678352832794, -0.02898423746228218, 0.013353370130062103, -0.0156447384506464, 0.007692935410887003, 0.01177157275378704, -0.047099217772483826, -0.00663704052567482, -0.036517687141895294, -0.03510165959596634, -0.0199789647012949, -0.1266891360282898, 0.12155497819185257, 0.033873945474624634, -0.0240379199385643, 0.001123541733250022, -0.042417172342538834, 0.014436833560466766, -0.05227968469262123, -0.015441563911736012, -0.03922750800848007, 0.0116962231695652, -0.04532516375184059, -0.04394345358014107, 0.02056082896888256, 0.032061923295259476, -0.012378702871501446, -0.023120377212762833, 0.06930635124444962, -0.021065199747681618, 0.02692905068397522, -0.014385991729795933, 0.05387072265148163, -0.07207661122083664, 0.05863475427031517, 0.07929891347885132, -0.08170682936906815, -0.02672615647315979, -0.051153477281332016, -0.0940651223063469, 0.08980944752693176, 0.01646599918603897, 0.038259122520685196, -0.030053015798330307, 0.01976439543068409, -0.0480416901409626, 0.04866362363100052, 0.006501701660454273, 0.009800948202610016, 0.0412488728761673, 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metabisulfite,\nsodium\tbisulfite,\npotassium\nbisulfite,\tsulfur\ndioxide\nShrimp,\tavocado,\tinstant\tpotatoes,\tinstant\tmashed\npotatoes,\tFrench\tfries,\n\tsausage,\tcanned\tfruits\tand\nvegetables,\tdried\tfruits\tand\tvegetables,\tacidic\tjuices,\nwine,\tbeer,\tcider,\tcolas,\tfresh\tfruits\tand\tvegetables\ntreated\twith\tsulfites\tto\tprevent\tbrowning,\tand\tmany
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treated\twith\tsulfites\tto\tprevent\tbrowning,\tand\tmany\nother\tprocessed\tfoods\nAcute\tasthma\tand\nanaphylaxis\tin\tpeople\nwith\tasthma;\nreactions\tin\tskin\tand\nmucous\tmembranes\nReactions\tto\tMicrobial\tContamination\tor\tToxins\tin\tFoods\nProteus\n,\nKlebsiella\n,\tor\nEscherichia\n\tcoli\nbacteria\tcause\nhistidine\tto\nbreak\tdown\tto\ta\nhistamine
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coli\nbacteria\tcause\nhistidine\tto\nbreak\tdown\tto\ta\nhistamine\nUnrefrigerated\tscombroid\tfish\t(tuna,\tbonito,\tmackerel);\nheat-stable\ttoxin\tproduced\nScombroid\tfish\npoisoning\t(itching,\nrash,\tvomiting,\ndiarrhea);\nanaphylactic-type\nreaction\nOther\tterms\tare\tused\tby\tclinicians,\tresearchers,\tpatients,\tand\tthe\tmedia\tbut\tare\tnot\tformally\taccepted
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has\tbeen\tproposed\tby\tVojdani\tto\trefer\tto\tthe\tconcept\tthat\twhen\tthe\nbody’s\tnormal\ttolerance\tof\tfriendly\tantigenic\tsubstances\t(autoantigens\tproduced\tby\tthe\tindividual’s\nimmune\tsystem)\tis\tdisrupted\tbecause\tof\tdisease,\tinjury,\n\tshock,\ttrauma,\tdrugs,\tor\tblood\ttransfusion,\tthe
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shock,\ttrauma,\tdrugs,\tor\tblood\ttransfusion,\tthe\ningestion\tof\tfoods\tcontaining\tantigenic\tsubstances\twith\ta\tcomposition\tsimilar\tto\tthose\tof\tthe\tbody’s\nautoantigens\tcan\tresult\tin\tthe\tproduction\tof\tantibodies\tthat\treact\tto\tthe\tfood\tantigens\tand\tthe\tbody’s\town\ntissues\t(\nVojdani,\t2015a\n).\t\nSensitivity-related\tillness\t(SRI)
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tissues\t(\nVojdani,\t2015a\n).\t\nSensitivity-related\tillness\t(SRI)\n\thas\talso\tbeen\tproposed\tas\ta\tcondition\tthat\noccurs\twhen\tan\tindividual\tis\texposed\n\tto\tsome\ttype\tof\ttoxin\tor\tstressor\tand\tthen\tbecomes\tsensitive\tto\ta\nfood,\tinhalant,\tor\tchemical,\talthough\tthe\tmechanisms\tare\tunclear\t(\nGenuis,\t2010\n)\t(\nBox\t25.1\n).\nBOX\t25.1
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Genuis,\t2010\n)\t(\nBox\t25.1\n).\nBOX\t25.1\nAdverse\tReactions\tto\tFoods:\tDefinitions\n•\t\nAdverse\tfood\treactions:\n\tencompass\tfood\tallergies\tand\tfood\tintolerances,\tboth\tof\twhich\tcan\nresult\tin\tdistressing\tsymptoms\tand\tadversely\taffect\thealth\n•\t\nAllergens:\n\tthe\tcomponents\n\tin\tfoods\tthat\ttrigger\tadverse\timmunologic\treactions;\tmost\toften\tare
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