document_id int32 185 2.68k | question stringlengths 11 194 | id int32 225 5.32k | answers sequencelengths 1 1 | chunks sequencelengths 5 52 | correct_chunks sequencelengths 0 1 | num_words int64 404 5.47k | num_tokens int64 652 7.87k |
|---|---|---|---|---|---|---|---|
630 | What is the main cause of HIV-1 infection in children? | 262 | [
"Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide."
] | [
"Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/\n\nBoily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel\n2009-10-07\nDOI:10.13... | [
1
] | 4,636 | 7,055 |
630 | What plays the crucial role in the Mother to Child Transmission of HIV-1 and what increases the risk | 276 | [
"DC-SIGNR plays a crucial role in MTCT of HIV-1 and that impaired placental DC-SIGNR expression increases risk of transmission."
] | [
"Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/\n\nBoily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel\n2009-10-07\nDOI:10.13... | [
2
] | 4,636 | 7,055 |
630 | How many children were infected by HIV-1 in 2008-2009, worldwide? | 278 | [
"more than 400,000 children were infected worldwide, mostly through MTCT and 90% of them lived in sub-Saharan Africa."
] | [
"Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/\n\nBoily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel\n2009-10-07\nDOI:10.13... | [
3
] | 4,636 | 7,055 |
630 | What is the role of C-C Motif Chemokine Ligand 3 Like 1 (CCL3L1) in mother to child transmission of HIV-1? | 316 | [
"High copy numbers of CCL3L1, a potent HIV-1 suppressive ligand for CCR5, are associated with higher chemokine production and lower risk of MTCT of HIV-1 among South African infants"
] | [
"Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/\n\nBoily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel\n2009-10-07\nDOI:10.13... | [
38
] | 4,636 | 7,055 |
630 | What is DC-GENR and where is it expressed? | 305 | [
"Dendritic cell-specific ICAM-grabbing non-integrin-related (DC-SIGNR, also known as CD209L or liver/lymph node-specific ICAM-grabbing non-integrin (L-SIGN)) can interact with a plethora of pathogens including HIV-1 and is expressed in placental capillary endothelial cells"
] | [
"Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/\n\nBoily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel\n2009-10-07\nDOI:10.13... | [
5
] | 4,636 | 7,055 |
630 | How does the presence of DC-SIGNR affect the MTCT of HIV-1? | 306 | [
"the presence of DC-SIGNR at the placental endothelial cell surface may protect infants from HIV-1 infection by capturing virus and promoting its degradation/presentation."
] | [
"Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\n\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/\n\nBoily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel\n2009-10-07\nDOI:10.13... | [
40
] | 4,636 | 7,055 |
630 | Why do low levels of DC-SIGNR enhance Mother to Child Transmission of HIV-1? | 307 | ["in placenta containing low levels of DC-SIGNR, HIV-1 would preferentially binds CCR5 on endothelia(...TRUNCATED) | ["Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\(...TRUNCATED) | [
40
] | 4,636 | 7,055 |
630 | What is the percentage of Mother to Child Transmission of HIV-1, when there is no intervention? | 277 | ["Without specific interventions, the rate of HIV-1 mother-tochild transmission (MTCT) is approximat(...TRUNCATED) | ["Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\(...TRUNCATED) | [
3
] | 4,636 | 7,055 |
630 | Does C-C chemokine receptor type 5 (CCR5) affect the transmission of HIV-1? | 312 | ["Genetic variants in CCR5 have been shown to influence vertical transmission of HIV-1. CCR5 promote(...TRUNCATED) | ["Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\(...TRUNCATED) | [
38
] | 4,636 | 7,055 |
630 | How does Mannanose Binding Lectin (MBL) affect elimination of HIV-1 pathogen? | 318 | ["Mannose-binding lectin (MBL) is an innate immune receptor synthesised in the liver and secreted in(...TRUNCATED) | ["Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1\(...TRUNCATED) | [
38
] | 4,636 | 7,055 |
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