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When to seek urgent medical care when I have Nocturia ?
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We consider the problem of identifying infected individuals in a population of size N. We introduce a group testing approach that uses significantly fewer than N tests when infection prevalence is low. The most common approach to group testing, Dorfman testing, groups individuals randomly. However, as communicable diseases spread from individual to individual through underlying social networks, our approach utilizes network information to improve performance. Network grouping, which groups individuals by community, weakly dominates Dorfman testing in terms of the expected number of tests used. Network grouping's outperformance is determined by the strength of community structure in the network. When networks have strong community structure, network grouping achieves the lower bound for two-stage testing procedures. As an empirical example, we consider the scenario of a university testing its population for COVID-19. Using social network data from a Danish university, we demonstrate network grouping requires significantly fewer tests than Dorfman. In contrast to many proposed group testing approaches, network grouping is simple for practitioners to implement. In practice, individuals can be grouped by family unit, social group, or work group.
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How can we evaluate the clinical likelihood and risk scores of pulmonary embolism?
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Hi I am 36 weeks pregnant. I feel like inside my tummy near belly button cracks. It feels warm and a little hurt. Every time I sit and bend to get something, I feel like my tummy pop and skin cracks. I'm wondering if the skin cracks and have breed inside. I didn't see any blood come out when I urinate.Thanks!
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Hi, I just noticed that my 8 year old boy s scrotum is swallow on one side. He does not have any pain and it does not feel hard. he is not sure how long it has been swollen. The bump seems to be separate from his testicles, but is on the left side. Any idea what could cause the the swelling?
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hi have two question. i had my period on the 27th of jan, i had it for 5 days which is normal but flow on the last two days was a bits smaller than usual. i took a test today and it came back negative. is it right.today i had sex with my boyfriend we used condoms but the broke a some point i had also 2 tabs of today contraceptive. he didnit ejculate in me. i was scared so went to the pharmacy and the pharmacist gave me primolut N as an EC - would i get pregnant and is primolut N a god EC
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Hi, I have a prolapsed bladder and for about 2 weeks my urine has had a rubber smell and I have lower middle back pain sometimes so bad I cannot stand up straight . What could be going on ? I don't know. If this helps but I also have a prolapsed bowel and uterus as well.
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Between cerebral palsy and spinal dysraphism, which condition typically manifests at birth?
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I have epidydimitis since 4 months now, there is pain in scrotum , i have switched three doctors and tried so many antibitiocs( levofloxacin, doxyclicine, ciprofloaxcin, dietharizine, etc. ) but pain is still there. now what to do.. i am also getting pain in right testicle sometimes.. scrotal ultrasound show varicocle in left, doc said pain is due to epidymitis.. please suggest good remedy
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Hi i am diagonised with Dermatomyositis (DM) , taking streoids 30 mg ( prednisolone ) for 6 weeks . Now iam in 20 mg dosage past 1 week. My general physician would bring down the dosage to 5mg (0r) 7.5 mg shortly. My CPK is at 50 , ESR is 30 , LDH - 209 , SGOT -27, SGPT-50 . Only ESR is alone above the range . I am not diabetic , after taking this streoid my fasting sugar increased to 141. Kindly advise , how to bring down ESR count . Blood sugar is because of Streoid . regards AAAA
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on the 4 of july I ran into a pole waist high I was going so fast it knock the poop out of me and yes I do mean tht..I was rush to the hospital and my stomach was cut up a little but it was my insde tht hurt the worse .when I ran into the pole it hit me wright above my bellybutton and the hospital took a CT SCAN and said everything was fine..now its been a week in a half and my left side of my stomach is still swollen and wright ware my bellybutton is at its heallin BUTits getting really hard around it and my stomach still hurts ..im 20 years old and I was going to the gym daily so I was in good shape but iam getting worried ...wht should I do
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I recently been having little red bumps on the head of my penis almost like if it were having a allergic reaction, and also beginning to smell like fish odor. Not sure if I am having a reaction to something or if I have an std (which I doubt since I haven t been sexually active in a while) help?
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hello, in December 2010 I had a chest infection with a very bad cough. I still have the cough but I've now been diagnosed with depression - I only cough now (dry hacking cough) when I associate it with the stress that has caused my depression - is this a stress cough or would I still have the infection from Dec 2010?
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I have a swollen ankles, both feet, especially in the evening. What can be the reason? I spent a lot of time working on my computer. Recently I got a high blood pressure. I also drink 2 - 3 bottles of beer daily. To ad to it, I have a spinal stenosis and pain disturbs mi with walking. Any suggestions, Doctor?
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i got alot of stretch marks , mostly on my legs though i know im not over weight but what could i do to make them less noticeable and keep them that way and what might be causing them?
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Hi, i have had a cough for months. No coughing at night, mainly in the morning caused by this terrible constant tickle in the throat. Could lung cancer cause a tickle sensation in the throat and a constant need to clear the throat? I recently had sinusitus with a really bad cough and headaches. I had a ct scan on my brain as the headaches went on for weeks but it was all clear. I dont feel like my nose is leaking at the back of my throat, as in post nasal drip thats why im paranoid about lung cancer. Would i have any other symptoms with lung cancer? I had a chest xray about a year ago for another condition but it was all clear.
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My 10 year old gets stomache pains and starts shaking uncontrollably. Last for and hour or more and goes away. May come and go for hours then gone for days and comes back? Has been going on for 3 months? We have tried possible low blood sugar . Juice or candy does not help. Should I take her to an immediate care as is going on now.
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Hello doctor,I am trying to conceive but my husband and I did cocaine a week ago. How long should my husband and I wait to safely continue to try to get pregnant? How long until it is out of our system? How long does cocaine stay in sperm? Thanks in advance.
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I am allergic to oak, birch, beech and alder mostly and another insignificant one like elm. I started getting strange feelings on my lips and reported them to my allergist after remembering having read that you can get symptoms from fruits etc.. and that cantaloupe is one of the culprits.By the way I have been on shots for 2 years and have had no symptoms since the spring I first began them. My doctor said I should stay away from it, of course, and I have but the lips still feel weird and it's been at least 5 days. What other of the trees I have mentioned can cause this and what other fruits am I unaware of being the cause.
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Hi, Im a super healthy person However, I have been having pain in my hips. When I stand up after being seated, it is uncomfortable and also awkward. I wonder if it may be simply caused by standing up too long at work. I work at Nordstrom and I typically stand up 8 hours a day.
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Hi doctor, I had sex for the first time. After that, I did not get my periods yet. I went to a gynecologist. She had taken my blood sample and it was negative. But, still I have not gotten my periods and it has been a week ahead. What could be the reason for my late periods?
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RNA-dependent RNA polymerases (RdRps) of the Nidovirales (Coronaviridae, Arteriviridae, and 12 other families) are linked to an amino-terminal (N-terminal) domain, called NiRAN, in a nonstructural protein (nsp) that is released from polyprotein 1ab by the viral main protease (M(pro)). Previously, self-GMPylation/UMPylation activities were reported for an arterivirus NiRAN-RdRp nsp and suggested to generate a transient state primed for transferring nucleoside monophosphate (NMP) to (currently unknown) viral and/or cellular biopolymers. Here, we show that the coronavirus (human coronavirus [HCoV]-229E and severe acute respiratory syndrome coronavirus 2) nsp12 (NiRAN-RdRp) has Mn(2+)-dependent NMPylation activity that catalyzes the transfer of a single NMP to the cognate nsp9 by forming a phosphoramidate bond with the primary amine at the nsp9 N terminus (N3825) following M(pro)-mediated proteolytic release of nsp9 from N-terminally flanking nsps. Uridine triphosphate was the preferred nucleotide in this reaction, but also adenosine triphosphate, guanosine triphosphate, and cytidine triphosphate were suitable cosubstrates. Mutational studies using recombinant coronavirus nsp9 and nsp12 proteins and genetically engineered HCoV-229E mutants identified residues essential for NiRAN-mediated nsp9 NMPylation and virus replication in cell culture. The data corroborate predictions on NiRAN active-site residues and establish an essential role for the nsp9 N3826 residue in both nsp9 NMPylation in vitro and virus replication. This residue is part of a conserved N-terminal NNE tripeptide sequence and shown to be the only invariant residue in nsp9 and its homologs in viruses of the family Coronaviridae. The study provides a solid basis for functional studies of other nidovirus NMPylation activities and suggests a possible target for antiviral drug development.
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My bp goes up n down lately, from 140/100 to 200/100 n i cant sleep, urinate a lot every now n then, burning sensation in my chest n headache. I was just discharged from hospital today after 3 days rest. My xray n ct scan showed alright. They just give me pain killer for my headache n ii'm seeing the doctor again tomorow. Only then they know whether i shoul be on medication or not.. I cant sleep tonight. Please help. Whether i shoul go back to the hospital right now for bp monitoring?. Tq.
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How does increased phosphofructokinase-2 affect glycolysis and gluconeogenesis?
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BACKGROUND: The first case of SARS-CoV-2 in Greece was identified in February 2020. During the COVID-19 pandemic two lockdowns took place (March-May 2020/November 2020-ongoing). People who use drugs (PWUD), as well as the homeless, constitute vulnerable social groups. The main aim of this study is to assess the impact of social distancing measures during the COVID-19 pandemic on these groups. METHODS: A program was implemented in Athens between December 2020 and January 2021 in a sample of PWUD and homeless recruited both in Substitution Treatment Units and the Homeless Shelters. The interview was conducted with a structured questionnaire. RESULTS: The study included 303 participants (215 PWUD and 88 homeless individuals (HI)). The mean (SD) age was 49.2 (9.7) and 61.9 (10.2) years for PWUD and HI respectively. Chronic hepatitis C was reported by 33% of PWUD and 1.1% of HI. HIV infection was reported in 9.3% of PWUD. Testing for SARS-CoV-2 was reported by 55% and 100% of PWUD and HI respectively; 0.8% of PWUD and 5.7% of HI were found positive. Compliance with individual measures against SARS-CoV-2 was reported to be high (98-100%) during lockdowns. 88.8% and 98.9% of PWUD and HI reported change in the quality life. Feelings of isolation were reported by 46.6% and 11.5% on PWUD and HI, respectively. PWID enrollment in OST programmes during the 1st and 2nd lockdown was 67.1% and 92.9% respectively. OST attendees did not report changes in treatment during lockdowns. Access to hygiene materials was 9.8% and 100% in 1st and 2nd lockdown. Access to drugs was high (91.5% and 94.3%) in both lockdowns. The illegal drug use as compared to regular use was increased 12.2%/14.3%, decreased 40.2%/40%, stable 47.6%/45.7% for 1st/2nd lockdown respectively. CONCLUSIONS: The population studied is well-aware and compliant with the prevention measures against COVID-19 with access to frequent laboratory testing, low levels of SARS-CoV-2 and access to prevention materials. KEY MESSAGES: Among PWUD the OST services provision was stable. Provision of antiseptics was higher during the 2nd lockdown while changes in drug use were similar during the 1st and 2nd lockdown. Limitation: This study does not assess PWUD with limited access to OST and HI living in the streets.
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I have a red lump on my right breast, iv had it for years, it started off the size of a pea and currently after having a baby its doubled in size, i have went to the doctor, and hospital, and they told me its a scar and theres nothing they can do to remove it, they can only to insert steroids which may make it worse, im terribly self consious because its on my chest clevage area and i always try to keep it covered, please help
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Hi I have these brown dry spots on my legs and they re starting to grow all over my legs now I don t see anything wrong with my arms or my thighs it s just below my knees I ve never had a history of psoriasis or eczema and neither does my family I m scared and I don t have health insurance that s why I haven t gotten it looked at yet
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What are the reasons behind major depressive disorder?
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When straightening up after bending over for a couple minutes I had a sharp pain in my back. Now I cannot straighten my back and have trouble walking because of the pain. The only way to relieve the pain so far has been to lay down in the fetal position. What may be the problem?
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Rught after hurting my lower back yesterday, both my legs became extremely weak and shakey feeling as though they couldn t support me anymore. My lower back feels very very weak now too. What s wrong with me? Do i have to pay to continue to consult I m sorry, i just read that I have to pay. I have no money at this time. Thank you anyway for taking the time to read my question.
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Doc im suffered from typhoid im in medication for past 4days now im thinking that im free of temp and bodypains not completely bt some betterment is there bt nw in my 5th day i hv severe headache especially at the back side.in some position it disappears please help me
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i am twelve (12) years old boy & i am in growth harmon difficiency, i live in pakistan and in this mirpurkhas city sir i may one question to u, pakistani doctors suggest me for this diseases growth harmons injections made by italy ,lilly company. sir plz give me ur suggestion.... i am weightless ,& also hieghtless.. if contact after then i will send my reports to u
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I have a 6yr old girl who is CONSTANTLY complaining of pain in her tummy. We have had her the docs numerous times, she is not constipated. Doc has examined her and taken blood tests. I am at the end of my tether because it is upsetting her. Can you help??
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EIC services should be made available to parents who are interested in the service.
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Hello, I noticed in the last week I have a small lump in my groin area. There is no severe pain or discomfort, but I know it is there. It is more noticeable when I cough. I also noticed a foul order in my urine. My last 2 periods I had some clotting/bleeding 2 days after I thought my period ended. I tend to clot alot anyway during menstral periods. I thought maybe you might have an idea what might be wrong with me. Thanks
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What are the typical symptoms of Lyme disease during Stage 1?
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My spouse told me that my breath smelled like metal. She then stated that it was coming from my pores and I smelled like metal all over. Not sure what can cause this. As far as I know, Sertraline 100 mg does not cause this. I did just start Nicotine patches, but I didn t think that was a side effect. Please help.
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My 4 year old son has had a skunk oder every time he sweats or when he gets wet in the sprinkler or even the shower. I only notice the smell from his head. at first I thought he rubbed up againt a dog that had been sprayed but it has been 2 weeks. after he gets out of the shower and sits down with me and is completely dry he does not have this oder. what could this be?
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Hello doctor,I am trying to conceive but my husband and I did cocaine a week ago. How long should my husband and I wait to safely continue to try to get pregnant? How long until it is out of our system? How long does cocaine stay in sperm? Thanks in advance.
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Several human pathologies including neurological, cardiac, infectious, cancerous, and metabolic diseases have been associated with altered mitochondria morphodynamics. Here, we identify a small organic molecule, which we named Mito-C. Mito-C is targeted to mitochondria and rapidly provokes mitochondrial network fragmentation. Biochemical analyses reveal that Mito-C is a member of a new class of heterocyclic compounds that target the NEET protein family, previously reported to regulate mitochondrial iron and ROS homeostasis. One of the NEET proteins, NAF-1, is identified as an important regulator of mitochondria morphodynamics that facilitates recruitment of DRP1 to the ER-mitochondria interface. Consistent with the observation that certain viruses modulate mitochondrial morphogenesis as a necessary part of their replication cycle, Mito-C counteracts dengue virus-induced mitochondrial network hyperfusion and represses viral replication. The newly identified chemical class including Mito-C is of therapeutic relevance for pathologies where altered mitochondria dynamics is part of disease etiology and NEET proteins are highlighted as important therapeutic targets in anti-viral research.
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sir.....i was wearing braces for my teeth 2 years ago..the treatment was because my upper jaw was protruding which i inherited and there was gap between my centre 2 teeth...i wore my clib for 8 months.....and my doctor made the gap at the centre 2 join by fixing it with lazer treatment.now that laser gum has come out and my treatment now is a failure...and the gap is starting to fall again..what should i do now??
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What are the potential toxic effects of quinidine, an antiarrhythmic drug, and what is cinchonism?
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My 5 year old has had a really bad cough for over 5 days now; he is unable to eat a thing and has lost 2kgs. There is no phlegm, but he get severe bouts of coughing which results in him being sick. The cough is generally worst at night, and nothing seems to be working.there is history of asthma on fathers side; could this be related? Please help.
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I was looking for information about nausea and dizziness after eating mango. I had my gallbladder removed a week ago and after eating about two bites of mango this morning I felt these symptoms but didn't consider it was due to the mango. Then at noon I ate about a half cup of it and have felt awful ever since; it's as if I'm having another attack after the gallbladder has been removed. Any insight?
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What are the different routes of administration for heparin and in what situations are they typically used?
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My son only 4months old,he had eczema since 2 months ago ,My doctor tell me to use fucicort for my son twice a day for 3days,it was very effective after 3days my son eczema was gone and I stop using it,but after few days my son eczema back again(during these few days I am using Aqua cream and atopiclair cream to maintain his face),so doctor may I know how to keep away the eczema from my son and how to maintain the eczema not to come back again????
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i have sever stomach pain. the pain is right where my rib cage comes together its like someone is stabbing me with a knife and going right upwards. i am feeling light headed and dizzy i am extremely weak. i can t stand up straight. iv been looking on the internet and everything is pointing to my gallbladder . can you please help.
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What is the definition of Epidermolytic Hyperkeratosis?
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Secreted phospholipases A2 (sPLA2s) form a widespread group of structurally-related enzymes that catalyse the hydrolysis of the sn-2 ester bond of glycerophospholipids to produce free fatty acids and lysophospholipids. In humans, nine catalytically active and two inactive sPLA2 proteins have been identified. These enzymes play diverse biological roles, including host defence against bacteria, parasites and viruses. Several of these endogenous sPLA2s may play a defensive role in viral infections, as they display in vitro antiviral activity by both direct and indirect mechanisms. However, endogenous sPLA2s may also exert an offensive and negative role, dampening the antiviral response or promoting inflammation in animal models of viral infection. Similarly, several exogenous sPLA2s, most of them from snake venoms and other animal venoms, possess in vitro antiviral activities. Thus, both endogenous and exogenous sPLA2s may be exploited for the development of new antiviral substances or as therapeutic targets for antagonistic drugs that may promote a more robust antiviral response. In this review, the antiviral versus proviral role of both endogenous and exogenous sPLA2s against various viruses including coronaviruses is presented. Based on the highlighted developments in this area of research, possible directions of future investigation are envisaged. One of them is also a possibility of exploiting sPLA2s as biological markers of the severity of the Covid-19 pandemic caused by SARS-CoV-2 infection.
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Hello doctor, I am a 61 year old male. For many years, I was treated for hemochromatosis. Then, about 12 years ago, I had a genetic test. The results prompted the hematologist to abruptly stop the recurring phlebotomies. I do not recall the test result and apparently, it cannot be located. But, I remember it was something about the homozygotic versus heterozygotic situation. My current iron level is high at 216 mcg/dL, IBC is normal at 259 and iron saturation is high at 83%. The ferritin is also high at 1042 mg/dL. All blood count factors are in the normal range. Should anything be done to pull out some of the iron? Currently, I am taking Losartan, Hydrochlorothiazide and Relpax.
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Hello doctor, My father is 58 years old and weighs 49 kg and 5.8 feet tall. He is on ART medicine since the last 13 years. He has AIDS. He had seizures last year, so he is also taking Ecosprin 75 mg, Septran, and Eptoin daily. I have two questions. Many doctors are surprised that he is only having one Septran tablet a day. I wanted to know that, is one Septran tablet enough? His MRI scans show some infections. I also want to inform you that my father has high BP problem, and he is on Telma since last year. Should we increase his dosage of Septran considering he has high BP problem? My other question is that, whether blood clots can cause seizures because as far as I have researched, Eptoin is being given only for the epileptic seizures. Is there a possibility that blood clots can cause seizures? He had seizures on the left side of his body and since then, he has never had seizures or any those symptoms like slurred speech or confusion or lack of coordination. Please help me. I have not attached any medical reports. But still, if you can guide to whatever extent, that would be of great help. Regards.
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Well I was a little different when I was younger expanding on events of ones life and making things up. and then It is like I suddenly woke up. But you have to know the expanding part went on and on until I hit 45 and then suddenly it went away. I was on all kinds of allergy meds. and now I am not could the things I experienced be just a chemical inbalance caused by meds
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MY MOTHER HAS JUST BEEN SENT TO EMERGENCY - WEEKS AGO SHE WENT AGAIN AND WAS NOT DIAGNOSED WHAT SEEM TO BE SOME INTERNAL BLEEDING SINCE SERVERE ANEMIA WAS PRESENT - NOW MY SIS HAS JUST GLEANED FROM RECORDS THERE OF ESO...ECTOMY ABOUT TO TAKE PLACE ANY TIME AND WE JUST HAVE NO CLUE AND NOT BEEN INFORMED AS TO WHAT IS REALLY GOING ON - LAST VISIT WAS DISCOVERED PANCREATITIS?? HELP PLEASE URGENTLY
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OBJECTIVE: The objective of the study was to evaluate the prevalence of anxiety and depression among medical trainees during the initial wave of the COVID-19 pandemic. METHODS: This was a cross-sectional study of the prevalence of depression and anxiety among medical students, residents, and fellows at a medical university hospital in New York using self-reported PHQ-9 and GAD-7 screening tools administered via an anonymized survey. The study was conducted in April 2020. RESULTS: The authors received 438 responses (33.4% response rate). Nearly half (44.5%) were medical students and female (56.6%). The prevalence of positive screen for depression (45.3%) and anxiety (48.1%) was high. Many reported moderate to severe depression (17.2%) and anxiety (20.3%). Over half (57.3%) experienced significant mood changes and inability to concentrate, and 14.6% had reconsidered their choice of profession since the start of the pandemic. Those who had reconsidered their profession had higher PHQ-9 [8.1 (6.4) vs 4.4 (4.3), p < 0.0001] and GAD-7 scores [8.3 (6.1) vs 4.7 (4.6), p < 0.0001], indicating adverse mental health partly contributed to their reconsideration of choice of profession. Women were more likely to screen positive for anxiety (OR: 1.68) and medical students more likely to screen positive for anxiety (OR: 2.55) and depression (OR: 2.74). CONCLUSION: The COVID-19 pandemic has placed great strain on health-care resources, including the mental health of medical trainees.
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My fiance just started taking Sulfamethoxazole / Trimethoprim (4 pills so far - Double Strenght dose) for an abcess that was drained. She is experiencing sore throat, body weakness, sore muscles, headache, nausea, hypersensitivity (to light sounds, etc.), and chills. I m really worried about her. What should she do? Please help. Thank you for your time and advice.
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Introduction: Severe acute respiratory syndrome coronavirus 2 also called coronavirus disease 2019 was first reported in the African continent on 14 February 2020 in Egypt As at 18 December 2020, the continent reported 2,449,754 confirmed cases, 57,817 deaths and 2,073,214 recoveries Urban cities in Africa have particularly suffered the brunt of coronavirus disease 2019 coupled with criticisms that the response strategies have largely been a 'one-size-fits-all' approach This article reviewed early evidence on urban health nexus with coronavirus disease 2019 preparedness and response in Africa Methods: A rapid scoping review of empirical and grey literature was done using data sources such as ScienceDirect, GoogleScholar, PubMed, HINARI and official websites of World Health Organization and Africa Centres for Disease Control and Prevention A total of 26 full articles (empirical studies, reviews and commentaries) were synthesised and analysed qualitatively based on predefined inclusion criteria on publication relevance and quality Results: Over 70% of the 26 articles reported on coronavirus disease 2019 response strategies across Africa;27% of the articles reported on preparedness towards coronavirus disease 2019, while 38% reported on urbanisation nexus with coronavirus disease 2019;40% of the publications were full-text empirical studies, while the remaining 60% were either commentaries, reviews or editorials It was found that urban cities remain epicentres of coronavirus disease 2019 in Africa Even though some successes have been recorded in Africa regarding coronavirus disease 2019 fight, the continent's response strategies were largely found to be a 'one-size-fits-all' approach Consequently, adoption of 'Western elitist' mitigating measures for coronavirus disease 2019 containment resulted in excesses and spillover effects on individuals, families and economies in Africa Conclusion: Africa needs to increase commitment to health systems strengthening through context-specific interventions and prioritisation of pandemic preparedness over response Likewise, improved economic resilience and proper urban planning will help African countries to respond better to future public health emergencies, as coronavirus disease 2019 cases continue to surge on the continent
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25 year old Male has hard lump under nipple of left breast - does not hurt - a little if pushing on it - no discharge from nipple - lump about quarter size - could it be cyst? - booking for x-ray - but should it not be a ultrasound? thank you for your time. Lori
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I was travelling for 3 days last week and could not find space for bath. After that (Four days before) I started itching on some parts of my body chest area perhaps and unknowingly I scratched, upon which I found the next day it s like a ringworm, round shape rashes. It spreads also first just like a pimple that itches and then becomes bigger and round. I was using itchguard for last 4 days and I can t make out it s better or not. Is it okay to use quadriderm RF. Kindly suggest me.
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Hi, Since about the age of 14 I ve had a habit of scratching my scrotum , this is mostly after i play sport but also sometimes when the area is dry and not even that itchy. Im now in my early 30 s and I have white patches on my scrotum below my penis . Im sure they are a result of years of habitual scratching. I doubt it a type of STD as I had never had sex before it started. there is also no pain at all unless I have scratched too hard. Im 32 of good health. Any advice on this would be very much appreciated. thank you.
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I HAVE AN UTI WITH E-COLI BACTERIA AND I AM RECEIVING IV INFUSION AT A INFUSION CLINIC. I AM RECEIVING MERMUM ONCE A DAY. WILL THIS GET RID OF THIS INFECTION? IT SEEMS THAT I AM HAVING UTI EVERY OTHER MONTH. COULD THIS BE CAUSED BY MY KIDNEY FAILURE STAGE 3?
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My son is 2 years old he is in coma from last one month , cause he had fits . Now he can moves has eyes but dont know why he doesnt knows who am I ? He was close to death. Now my question is when he will get out from the bed and play and walk like before? Everyday psytherapy doctor is visiting my home and giving him exercises
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HiI have got pain in one of my tooth left upper side... I m not able to eat anything from there. anything touches it causes severe pain... it seems root have got exposure... and got infectious a lot... I have started taking Ceff 500 and Buta proxyvon twice a day... pleae suggest further.. is it fine or not..
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What to expect if I have Sarcoidosis (Outlook/Prognosis)?
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Is tolerance or addiction a potential risk associated with the use of buspirone?
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should have detailed sonographic evaluation of abdomen and pelvis for abdominal pain I am a 17-year-old girl and have been told bymy doctor that I have an ovary cyst. I was told these go away on their own. I've had very sharp pains from it causing naseua once every 4-6 months for the past year and a half. I was prescribed birth control, but I don't want to take it because I don't want to rely on it each time a new cyst could form. I cannot stand when the pain happens though and it feels like I'm being stabbed in the left ovary and the pain moves all the way to the right. Is this the same cyst that keeps causing the pain, or is it a new one? I read they are supposed to go away in 1-3 months on their own. Are there any natural ways of making the cyst go away? If not, how do I stop them from reforming other than birth control? Also can I get more information about cysts because my doctor did not tell me much about it or what birth control will do other than stop ovulating.
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hi ive had very serve pain in my left ribs and it runs round my back and down my arm ive had this for a fair few months now i had ultra sound and said they think it could be nerve irataion. Is there any treatment for this as the painrelif does not seem to work and it affects my breathing
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My son, who is 33 years old, has been suffering from intermittent epileptic seizures (TONIC) with certain psychotic problems like low self-confidence, poor concentration and dis-interest in work , non-socialization, rare but sudden bursts of anger etc. From September, 1998 to July, 2011, he had in all 43 irregular seizures. He has been on different medicines for cure since 1998 itself as per different neurologists advice in the order given- DILANTIN-100+100mg/day ( 1 seizure in 1 year intake during 1998-99); TEGRETOL-100+100mg / d ( 2 in 4 months - 1999); ZEPTOL- 200+200 mg / d (30 in 2 yrs -1999-2001); EPILAX CHRONO 700+700 mg / d ( 3 in 4 yrs- 2002-2006); DEPAKOTE -500+500mg / d (NIL in 8 months-2007); TORVATE -500+500 mg/d +T.EPTOIN-100mg/d (7 in 4 yrs-2008-11). 20% of the seizures were due to non-intake of medicine for a day or two and rest may be due to non-suitability or inadequate dosage of medicines taken. presently he is on EPILAX CHRONO -500+500 mg / d +RISDONE-1 mg/d+NEXITO-5 mg/d from July, 2011. Today, ie on 16-4-2012 he is on severe tonic seizure twice at 1.30 AM and 5.30AM. Advice sought to do what immediately.
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Hello doctor,I am trying to conceive but my husband and I did cocaine a week ago. How long should my husband and I wait to safely continue to try to get pregnant? How long until it is out of our system? How long does cocaine stay in sperm? Thanks in advance.
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My one year old son just bumped his head into a pulled out drawer. He hit near his temple. He held his breathe briefly and cried for about a minute. He then seemed fine. An hour later he has some mild swelling where he hit his head. He is acting fine in every other way.
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Hi, my name is Wesley. I have had this cough for about 5 days now, along with a slightly stuffy nose. I am more worried about my cough though, because i smoke regularly and i am only 21. After i acquired this cough it wasnt a very serious thing, but i tried to smoke a cigarette and i could barely take 2 puffs of it. So i have not taken a puff of a cigarette for about 4 days now and still have the cough and slightly stuffed nose. Will my throat be alright ?
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The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and economy. In the wait for an effective global immunization, the development of a specific therapeutic protocol to treat COVID-19 patients is clearly necessary as a short-term solution of the problem. Drug repurposing and herbal medicine represent two of the most explored strategies for an anti-COVID-19 drug discovery. Clove (Syzygium aromaticum L.) is a well-known culinary spice that has been used for centuries in folk medicine in many disorders. Interestingly, traditional medicines have used clove since ancient times to treat respiratory ailments, whilst clove ingredients show antiviral and anti-inflammatory properties. Other interesting features are the clove antithrombotic, immunostimulatory, and antibacterial effects. Thus, in this review, we discuss the potential role of clove in the frame of anti-COVID-19 therapy, focusing on the antiviral, anti-inflammatory, and antithrombotic effects of clove and its molecular constituents described in the scientific literature.
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Hello....when I was between 8to10 yrs old my penis tip skin can't b pull I mean can't open it blocked so the doctors had me done operation..while operating I heard d doctor say that I wunt b able to become a father....now m married for almost 2yr still my wife dint get pregnant....m I infertile? What shall I do please suggest...is there away to have a baby...?
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Which nerve supplies sensory innervation to the medial thigh?
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good afternun sir myself got married in the year 2011. I had an abortion of 3rd month pregnant and d&c also has done.3years has been completed. i using sum course and also has done follicullar study?1)normally wat is the size of an egg? 2)my mensses dates are getting varied.plz sir suggest me do i hav any chance 2 concieve.
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What muscles are responsible for lateral (external) rotation of the arm?
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Hi, may I answer your health queries right now ? Please type your query here... I am a 23year old female. Today i got a very nasty sunburn. It feels like there are needles in the areas of my skin that were burned. Also i am freezing cold and shaking uncontrollably. I realize i may have some sort of sun poisoning or bad burn but i want to know- is it bad to layer on clothes and blankets to deal with how very cold i am?
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Hello doctor. I ve had some white stuff growing on the left side of my oral cavity for a week now. It s white and resembles cottage cheese in appearance. It s not itchy or painful, but it does make me feel uncomfortable when eating. It s not on my tongue or any other parts of the oral cavity. I ve tried scrubbing it off, but it tends to return. What s going on?
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My 18 year old son had a virus where heran 104 fevers x 5days. day 6-8 down to 101 he had N/V and suffered from dehydration and required IV fluid replacement. The only abnormal labs are high bilirubin and mildly low platelettes. I was advised today that they want to do a glucose challenge? Why?
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My mother has one kidney after nephrectomy due to renal cell carcinoma. She is out of state on a trip and ct has revealed mutiple organs with tumors as the cancer has spread. She was released from hospital thursday and we have a flight for tomarrow to bring her home. She just called and said her ankles are swelling. What do i do? Can she fly? Emergency room? Is she in renal failure? She is weak and tired as cancer is taking over. I am a 5 hour plaine ride away, help
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Q:A 36-year-old nulligravid woman comes to the physician because of a 1-year history of pelvic discomfort and heavy menstrual bleeding. The pain is dull and pressure-like and occurs intermittently; the patient is asymptomatic between episodes. Menses occur at regular 30-day intervals and last 8 days with heavy flow. Her last menstrual period ended 5 days ago. She is sexually active and does not use contraception. Her temperature is 36.8°C (98.8°F), pulse is 76/min, and blood pressure is 106/68 mm Hg. Pelvic examination shows white cervical mucus and a firm, irregularly-shaped uterus consistent in size with a 5-week gestation. A spot urine pregnancy test is negative. Which of the following is the most appropriate next step in diagnosis??
{'A': 'Pelvic radiograph', 'B': 'Laparoscopy', 'C': 'Pelvic MRI', 'D': 'Pelvic ultrasound', 'E': 'Repeat β-HCG test'},
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SO I HAD A VEIN ON THE BOTTOM OF MY RIGHT LEG THAT I HAVE HAD FOR AWHILE AND I WOKE UP ON SATURDAY AND IT WAS VERY SORE AND I NOTICED THAT THE VEIN WASNT THERE ANYMORE THEN A COUPLE DAYS LATER IT WAS WARM AND TENDER TO THE TOUCH AND STILL IS AND THERE IS A BUMP AND IT LOOKS BRUISED DONT KNOW WHAT THAT COULD BE VERY WORRIED
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Q:A 72-year-old female is brought to the emergency department by ambulance because she was unable to walk. She says that she cut her leg while falling about a week ago. Since then, the wound has started draining fluid and become progressively more painful. She is found to have necrotizing fasciitis and is taken emergently to the operating room. Histological examination of cells along the fascial planes reveal cells undergoing necrosis. Which of the following represents the earliest sign that a cell has progressed to irreversible damage in this patient??
{'A': 'Chromatin dissolution and disappearance', 'B': 'Condensation of DNA into a basophilic mass', 'C': 'Fragmentation of the nucleus', 'D': 'Membrane blebbing from organelles', 'E': 'Ribosomal detachment from the endoplasmic reticulum'},
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I am having severe pain and discomfort in my very lower abdomen/female parts and also in my very lower rectal area. I have had a husband that passed from colon cancer and many female friends that have met their demise with ovarian/uterine/and other female oriented afflictions. I have experienced this pain on and off for over a month now. I would appreciate your input very much. Thank you.
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I was walking outside in the pasture and started feeling a stinging feeling behind my knee. As soon as I reached down I could feel a lump the size of a quarter. I took my pants off to let my daughter look at it and she could see the lump was turning purple already. I walked into the house and showed my husband. By this time, less than five minutes the lump had hardened and ran along the vein creating a long hardened purple bruise about one inch long. I put Benadryl cream on the area, but it continued to stay swolen and purple. Any suggestions?
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BACKGROUND In order to limit the spread of COVID-19, governments have ordered a series of restrictions that may affect glycemic control in individuals with T1DM, since physical activity (PA) was not allowed outside home. MATERIALS AND METHODS We retrospectively evaluated glycemic control of individuals with T1DM using HCL system in the period before the SARS-CoV-2 outbreak in Italy (February 10th - 23rd, 2020 - Time 1), when movements were only reduced (February 24th - March 8th, 2020 - Time 2) and during complete lockdown (March 9th-22nd, 2020 - Time 3). Information about regular PA (at least 3 hours per week) prior and during the quarantine were collected. RESULTS The study included 13 individuals with a median age of 14.2 years and a good glycemic control at baseline (GMI 7%, TIR 68%, TBR 2%). All individuals continued to show good glycemic control throughout the study period. There was an increase in TIR during the study period (+3%) and TIR was significantly higher in Time 3 (72%) than in Time 2 (66%). TBR was significantly lower in Time 3 (1%) both compared to Time 1 and Time 2 (2%). A meaningful variance in TIR at Time 3 between individuals who performed or not PA during quarantine and a significant increase in TIR between Time 2 and Time 3 both in individuals doing PA at baseline and during quarantine, was found. At logistic regression, only the presence of PA during quarantine significantly predicted a TIR >70 %. CONCLUSIONS Glycemic control of T1DM in adolescents using HCL system did not worsen during the restrictions due to COVID-19 pandemics and further improved in those who continued physical activity during the quarantine. Maintaining regular physical activity in a safe home environment is an essential strategy for young individuals with T1DM during the COVID-19 crisis.
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Hi doctor, I want to know about my ECG report. I have attached it. Please suggest.
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Hello doctor, My friend aged 30 had two drops of phenol mistaking for milk. He vomited and had lot of salt water. Please advice for any side effect.
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hi my husband 56 years old. who is healthy with no medical conditions and a check up 12 months ago. he has a cough, bp is up and pulse is 92. He also has a fever that comes and goes. this just started yesterday. The sore throat is better with advil. He is never sick is this possible the flu?
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What exactly is Asperger's syndrome?
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I had a laparoscopic done july 16 2013. Inside my belly button still has a cut on the top but its closing (some meat shows it looks a lil nasty) & im thinking about getting my belly pierced next week for my birthday. Will it be healed by that time? Can i get it pierced ? Is it ok ? Any info that i need to know ? Please help me !
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urgent
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I had my 2 lower wisdom teeth removed a week ago. Swelling on one side is completely gone, but on the others side there is still mild to moderate swelling. My gums are also swollen and my gums have a discharge of brown blood. The incision site is healing very well and does not hurt. I also can not open my jaw 100%. Is this normal? Should I be worried?
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So I'm a extreme anxiety person. and I freak out about things that arnt even possible. But I just want to make sure I'm OK.my head is throbbing like crazy.it's coming from a huge pimple I have on my scalp I hope it nothing to scary or they have nothing to do with with other. Just want to be sure so I can get some sleep. Sorry if I sound crazy.
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Have lower back pain and upper abdominal ache urine has turned dark yellow have been taken a laxative for the last couple of days and some hydrocodone for arteitis all meds by script except m magnesia over counter concerned that pain was really bad 2nights ago has gone down a little but still uncomfortable especially upper right side
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What to expect if I have Pica (Outlook/Prognosis)?
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non-urgent
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Could you explain what testicular cancer is?
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urgent
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OBJECTIVE: To determine the training surgical residents and faculty receive on opioid prescribing, and to identify opportunities for curricula development to fill training gaps. DESIGN: We conducted qualitative semi-structured interviews and surveys. After applying an overarching organizational framework, we used an iterative, team-based process to develop relevant inductive codes. We then performed thematic analyses to identify and catalogue critical domains related to surgeons' education about opioid prescribing. SETTING: Tertiary care academic medical center. PARTICIPANTS: Maximum variation purposive sampling was used to recruit general surgery residents and surgical faculty members. RESULTS: We interviewed 21 attending surgeons and 20 surgical residents. Surgeons reported minimal formal training on pain management and prescribing opioids. A minority of individuals described receiving opioid training in the form of continuing medical education, intern boot camp sessions, and medical school classes. Participants compensated for the lack of formal training during residency by informally learning from senior residents, consulting pain specialists, and seeking external learning resources. Increased surgical experience was correlated with increased comfort with pain management. A majority of surgeons desired formal training. The most commonly requested educational resources were opioid prescribing guidelines for common operations and recommendations for treating chronic pain patients. Residents requested that training occur early in residency to maximize the benefits received. Based on these findings, we developed a conceptual framework to explain how surgeons learn to prescribe opioids and to highlight opportunities for improvement. CONCLUSIONS: Although surgeons routinely prescribe opioids and desire education on opioids, a majority of them do not receive any training. Instituting formal educational programs is critical for improving opioid prescribing practices among surgeons.These programs should include standard prescribing guidelines and address management of acute postoperative pain in patients with chronic pain.
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My 15 yr old son has a concave chest that appears to be getting deeper. It first was noticed when he was about 10 yrs old. I am looking for information on treatment, Doctors to contact etc. in the Phoenix Az area. As well and any knowledge you may have on the subject.
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my sister has breast cancer she had chemo and radiation then they found lesions in her brain. She had 10 more radiation treatments on her head. That was 6 weeks ago. Her last Cat scan showed the lesions in her brain were significantly shrinking. Now she has no streength in her legs and her legs seem to be shrinling up??
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Anti-TNF treatment demonstrated a favourable long-term effect on anti-PC levels.
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non-urgent
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How is Gardnerella vaginalis classified based on its Gram stain?
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