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Good evening doctor,I am from India,New delhi region.I am 46 years male.I had a problem of acute rhinitis and nasal allergy and suffered very badly for many years leading to acute sinusitis and almost the need for sinus operation. A doc prescribed me Flomist nasal spray two times a day in each nostril to start with and then once a day as a maintenance dose.This is going on for last 3 years.I was also prescribed cetrizine tabs which i take regularly even now once a day. As a result of this treatment my probs are 95 % over unless I get exposed to severe dust/smoke. My Q : 1. Is Flowmist at this low dosage safe to continue?I heard this is a steroid and should not be taken for long intervals 2. is cetrizine safe? 3. Should I stop this treatment now that I am much better. Thanks in advance for your revert doctor. Regards
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Hello doctor, I am 22 years old. I have problems with my beard. My beard grows in patches, only in certain parts of my face. The remaining areas are clear without any facial hair. It makes me look awkward. Does any supplement encourage hair growth and solve my problem. Is that possible doctor?
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Hi doctor, I am a 26 year old male. I am 5 feet and 9 inches tall and weigh 255 pounds. When I eat spicy food, I poop blood. Sometimes when I have constipation as well, I poop a little bit of blood. I am really scared that I have colon cancer. I do have diarrhea often. I do not have a family history of colon cancer. I got blood tests done last night. Please find my reports attached.
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Hello doctor, I have attached a picture which is on my chest for about two years. It has not given me any problem. Around two years back I had a small acne like thing on my chest right side and it became like this ever since. The dermatologists I have visited have said it is nothing to worry about, but I just want an opinion. I fear and hope it is not a skin cancer.
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Hi, I am 28 years old and living in GCC. My problem is my hair which is totally white. I use black hair colour for my hairs. I don t know how my hair becomes white. one day somebody told me about amyway product and its usage. Can you guide me which amway product is good for my hairs. Also please confirm its good for my health or not...
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i hit my leg multiple times with a glass bottle , a metal 8 oz hammer , and my fist. I was mad and wanted 2 hit sumthing and it ended up being my leg. Now it hurts to walk and there s a large bump on it what happened please tell me i did nt break it
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Proteins p38 map kinase and ribosomal S6 kinase (S6K) as members of mitogen-activated protein kinases (MAPKs) play important roles against pathogens. In this study, Bmp38 and BmS6K were identified as differentially expressed proteins from iTRAQ database. Bmp38 and BmS6K were expressed, and recombinant proteins were purified. The bioinformatics analysis showed that both proteins have serine/threonine-protein kinases, catalytic domain (S_TKc) with 360 and 753 amino acids, respectively. The real-time quantitative polymerase chain reaction (RT-qPCR) results suggest that Bmp38 and BmS6K had high expression in the midgut and hemolymph. The comparative expression level of Bmp38 and BmS6K in BC9 was upregulated than in P50 in the midgut after Bombyx mori nucleopolyhedrovirus (BmNPV) infection. Western bolt results showed a positive correlation between RT-qPCR and iTRAQ data for Bmp38, but BmS6K data showed partial correlation with iTRAQ. Injection of anti-Bmp38 and anti-BmS6K serum suggested that Bmp38 may be involved against BmNPV infection, whereas BmS6K may require phosphorylation modification to inhibit BmNPV infection. Taken together, our results suggest that Bmp38 and BmS6k might play an important role in innate immunity of silkworm against BmNPV.
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I HAD A HEARTH CATH DONE ICANT FIND A DOCTOR TO FOLLOW UP PLUS I WAS TOLD I HAD A LITTLE CICCROISOF THE LIVER IDO NOT KNOW WHAT TO DO I HAVE NO MED INSURANCE AND NO JOB HOW DO I GO ABOUT A FOLLOW UP
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if i have upper wisdom tooth extracted because of pulp issues, what will be the consequence. Will the lower wisdom tooth surge and will i have to have that extracted too - in time? If the dentist says a root canal is possible on that wisdom tooth, is it a better option? Pros and Cons.
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OBJECTIVE To compare the ability of qualitative versus quantitative methods of end-tidal carbon dioxide (EtCO2) detection to maintain normocarbia during face mask ventilation (FMV) of preterm infants (<32 weeks) in the delivery room. STUDY DESIGN Preterm infants <32 weeks were randomly assigned to the use of a disposable PediCap EtCO2 detector (Covidien, Dublin, Ireland) (qualitative) or a Microstream side stream capnography device (Covidien) (quantitative) for FMV in the delivery room, via a NeoPuff T-piece resuscitator (Fisher and Paykel, Auckland, New Zealand). The primary outcome was the presence of normocarbia, based on partial pressure of CO2 (PaCO2) readings obtained in the neonatal intensive care unit within an hour of birth. Normocarbia was defined as a PaCO2 measure between 37.5 and 60 mm Hg (5-8 kPa). RESULTS Of the 59 infants included, 59% (35/59) were within the PaCO2 target range within an hour of birth. There was no difference in the primary outcome; 64% (21/33) of infants in the quantitative group were within the PaCO2 range compared with 54% (14/26) in the qualitative group (P = .594); and 93% of participants <28 weeks' gestation were within the PaCO2 normocarbic range (90% [9/10] in quantitative group and 100% [5/5] in the qualitative group [P = 1]). There was no difference in the intubation rate, days of ventilation, or bronchopulmonary dysplasia rates between the 2 groups. CONCLUSIONS Quantitative or qualitative EtCO2 detection methods are both feasible for FMV in the delivery room. Although there was no difference in the incidence of normocarbia, the use of either form of EtCO2 monitoring should be considered during newborn stabilization, especially in infants less than 28 weeks' gestation. TRIAL REGISTRATION ISRCTN: ISRCTN10934870.
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Q:What might make the nurse think a patient could not use an inhaler?? A:Severe leg ulcers.;B:Previous recovery from an acute exacerbation of asthma.;C:Forthcoming surgery.;D:Poor technique, physical impairment, or lack of understanding.
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Hi, my son age 2 1/2 just drank from up all his medicine from the Entrolzol suspension. Could have been approximately 30 ml. please let me know what I should do. He is ok and active at the moment but what symptopms sould we look out for. Your early response is appreciated as it is a holiday and i cannot contact his paediatrician
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I am a 47 year old woman usually very healthy, and I just had a mammogram last October with normal results and I just noticed a very tender lymph node under my left armpit. Do you think it maybe cancer? No history of breast cancer on my moms side. I am a non-smoker.
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STATEMENT OF PROBLEM: The COVID-19 pandemic impacted every area of our lives, including delaying urgent dental care. However, studies evaluating how patients using dental prostheses have been affected by the pandemic are lacking. PURPOSE: The purpose of this study was to investigate how patients using different types of dental prostheses were being affected by the COVID-19 pandemic. MATERIAL AND METHODS: A total of 129 randomly selected individuals from among those who had been examined in the same clinic before the COVID-19 outbreak were included in the study. The study participants were divided into 4 groups according to their type of prosthesis: complete dentures, implant-retained removable dentures, tooth-supported fixed partial dentures, and implant-supported fixed partial dentures. The Oral Health Impact Profile (OHIP-14) questionnaire was implemented by telephone interviews with the study participants, who were also asked about their concerns and steps made regarding prosthetic hygiene during the COVID-19 pandemic. Data were evaluated by the Kruskal-Wallis and post hoc Dunn tests, and multivariate logistic regression analysis with forward selection was carried out to identify predictors of the oral health-related quality of life (OHRQoL) status (&#945;=.05). RESULTS: OHIP-14 total scores did not vary significantly among the groups (P>.05). When the domain scores of OHIP-14 were considered separately, the analysis revealed that the implant-retained removable denture group had significantly poorer functional limitations when compared with the tooth-supported fixed partial denture (P=.005) and implant-supported fixed partial denture (P=.031) groups. The results of the multivariate logistic regression analysis indicated a statistically significant association between OHRQoL during the COVID-19 pandemic and the frequency of tooth or denture cleaning (1 time a day versus less than 1 time a day: P=.011; 2-3 times a day versus less than 1 time a day: P=.032). CONCLUSIONS: All prosthesis users exhibited increased interest in dental hygiene and an increase in the frequency of prosthesis cleaning during the pandemic. Furthermore, the study determined that the frequency of tooth or denture cleaning was associated with significantly improved OHRQoL during the time of the COVID-19 pandemic. Among the denture groups, those treated with implant-retained removable dentures had the poorest functional limitation in terms of OHRQoL, which can be linked to postponement of routine maintenance appointments. Therefore, providing all patients with scientifically sound information on prosthetic care during a pandemic would be highly beneficial.
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my husband has creatiine level pretty high but he has his usual morning walks, does his routine work , has appetite, he is on medication he has type II diabetes & hyper tension does he require dialysis now he does not want to go for dialysis is it advisable to go for transplantation Please advise. His creatine is nearly 8
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Which nerve and artery pass through the quadrangular space of the shoulder?
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I was shot through the right ankle area from inside to outside with 22 magnum bullet on Nov22 2014. It missed the artery, the bones, and most of the tendons. The doctor removed the parts of the bullet that was at the skin on the outside of the leg and left the small bits of shrapnel inside the leg. The wound has healed quickly and cleanly. The bullet seems to have hit or at least damaged the tibial plantar nerve. I am experiencing an interesting assortment of sensations in my foot. The area forward of the instep on the bottom of the foot has no feeling to touch but fizzes, bubbles, burns, tingles, stabs, and electric shocks causing me no shortage of miserable hours. It is generally worse evenings and unbearable at bedtime. My big toe and the one next to it are bending to the right and bend downward if I lift my toes toward my shins. My first question is
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lump size of a small grape on my11 year old neck, 1/2 inch to the right of center neck on the top of the breast bone. it is a hard lump does not move , no redness does not hurt no fever at this time I have no health insurance so whats the best course of action do i need to worry?
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For about a week now I have been feeling something almost like a pulse or muscle spasm in my left knee, right above the knee cap. It comes about every 5-10 minutes and only lasts for a second or two. At times it feels like a balloon inflating and deflating. I have never had any problems with my legs before so it has been freaking me out that it may be something serious. I am overweight right now, but I am consistently losing weight through diet and exercise. Please help me figure out what is going on. Thanks!
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Hi Dr. I am for the past one and a half years suffering from kidney stones, both sises . however, now both the kidneys are clear as per the ultrasound report and one 8 mm stone is lodged in ureter which is causing pain and further mild swelling in kidney. My Q is whether I should go for surgery or continue with medicines for its removal. I am concerned about swelling in kidney is it serious or cause any damage to my system, plz. advice.,
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I had a supernumeracy tooth removed from the bottom of my mouth,they also took out to teeth which were infected i had a blood clot and have been rinsing with salt water as advised however the blood clot has now disappeared and i have a massive hole i have rang the dentist and they said it can be normal for the clot to dislodge however i now have a dull ache along my gum line, any suggestions?
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Hi, I had hernia repair in my groin, after the surgery, my doctor along with the surgery team, made a statement or medical advice that i get underwear for great support because I have extremely Large Testicles and Penis...his words were "you need a good Jockstrap or we(the surgical team) likely will be performing this surgery again" he went on to say that I am too large to not have proper support....Jocks squash me, and pinch, boxers add no support at all, not to mention most underwear and support systems cause me to show through my clothes very embarrassingly through my pants, if I go commando I still show, I search everyday online hoping to find the right support for me, I have even thought of duct taping them to the inside of my thighs!, regular underwear, what fits me in my waist, does not fit me in my crotch and vise verse, I hurt myself just as much with current brands that i have found and it's the same thing when I don't wear any underwear....sitting on my genitals is not pleasant at all.
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I have experienced painful joints on my left side...in my shoulder, elbow, wrist and left buttock since taking pantoprazole for a few days when my doctor thought I might have a stomache ulcer. My elbow is not only hurting; it is also weak. Should I consult my doctor? This has been going on for a month and a half.
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My 5 year old has had a temp of over 102 for 5 days, he has bloodshot eyes, and a sore neck. He has been tot he Dr s twice. They say its a sinus infection, and pink eye. But now it appears that he has a big blood spot in his left eye. He was up crying that the back of his head by his neck was bothering him. Any advice?
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The current coronavirus disease 2019 (COVID-19) pandemic has not only caused global social disruptions but has also put tremendous strain on healthcare systems worldwide. With all attention and significant effort diverted to containing and managing the COVID-19 outbreak (and understandably so), essential medical services such as transplant services are likely to be affected. Closure of transplant programs in an outbreak caused by a highly transmissible novel pathogen may be inevitable owing to patient safety. Yet program closure is not without harm; patients on the transplant waitlist may die before the program reopens. By adopting a tiered approach based on outbreak disease alert levels, and having hospital guidelines based on the best available evidence, life-saving transplants can still be safely performed. We performed a lung transplant and a liver transplant successfully during the COVID-19 era. We present our guidelines and experience on managing the transplant service as well as the selection and management of donors and recipients. We also discuss clinical dilemmas in the management COVID-19 in the posttransplant recipient.
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What is the recommended 10-year cardiovascular risk threshold for adults aged 50 to 59 years to be prescribed low-dose aspirin (81 mg)?
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Hi I have had three months of continued pill taking. Three different contraceptive pills, lose train 20 was the last. I had a 7 day break and just had spotting, very light period. I ve then started a new packet for two days and felt I should stop taking it because of this and used other methods of contraception . I ve very concerned because I should be on day ten of taking my new packet but feel there may be something wrong.
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I have upper left shoulder pain for about a month now. Although it is subsiding, and I believe caused from tennis serving and smashing, how long does it take to heal..I haven t been to the Dr. yet and wonder if it is tendon or rotator cup problem...Currently I am resting it as much as possible and putting warm pad on area at night for 1/2 hour or so....that helps...periodically taking Ibiprophin as well.
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hi i got fracture on my right ankle at fibula bone. i got checked up from doctor , i get plaster on my foot n now its almost 2 weeks are passed. doctor advised me to take max rest n it will be removed after 4 weeks. so do i check it up again now or after 4 weeks .. n any further advise
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Hi! I had a cold sore blisters about a month ago on my chin and now it left me with a wound, it s also look like a cut it s not healing till now and black mark around the wound.I was using zovirax with panderm ointment and it didn t healed my wound completely..I am currently using bactroban cream..please help me !I don t know what to do anymore.
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The last couple of days I have had lower back pain and abdominal pain at the same time. It sems to be pushing against my bladder and making me use the bathroom more frequently. I have not done anything out of the ordinary, and i feel a like i can stretch the pain out of my back, but it is very sore by the top of my buttocks. Doesthis sound serious?
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I am a 44 year old female. 5'2 about 144 pounds (yes..I know I'm overweight). I have a history of heart problems. I had a stent put in 2 years ago. I take Asprin, Metoprolol, Plavix and Crestor. I do not have high blood pressure. It tends to run on the low side. For the past few days I have had a burning/cramping pain in my upper abdomen. Seems to get worse when I eat or drink. Now I feel like food is stuck in my esophagus. I am totally uncomfortable!
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Hello doctor, I had sex the last four weeks before my period and after 25 hours, I drank ECP and bled after four days. Then, I have not gotten my period this month. I went to the gynecologist yesterday and she said that she saw a dominant follicle on the right side of my ovary which will almost rupture. So, here are my questions: What does this dominant follicle mean? Do pregnant women have a dominant follicle when they are actually pregnant? Am I only ovulating right now? Am I safe from pregnancy? After how many days from now should I expect my period to arrive?
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SARS CoV-2 has particularly been efficient in ensuring that many countries are brought to a standstill. With repercussions ranging from rampant mortality, fear, paranoia and economic recession, the virus has brought together countries in order to look at possible therapeutic countermeasures. With prophylactic interventions possibly months away from being particularly effective, a slew of measures and possibilities concerning the design of vaccines are being worked upon. We attempted a structure-based approach utilizing a combination of epitope prediction servers to develop a multi-epitope-based subunit vaccine that involves the two major domains of the spike glycoprotein of SARS CoV-2 (S1 and S2) coupled with a substantially effective chimeric adjuvant to create stable vaccine constructs through MD simulations. The designed constructs were evaluated based on their docking with Toll Like Receptor (TLR) 4. Our findings provide an epitope-based peptide fragment; which can be a potential candidate for the development of a vaccine against SARS-CoV-2. Recent experimental studies based on determining immunodominant regions across the spike glycoprotein of SARS-CoV-2 indicate the presence of the predicted epitopes included in this study.
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Day I had mammogram had intense itching on left side. Blister developed and then more red itchy spots. 3 days later I was diagnosed with shingles. Has been a month. No pain, but rash spread to stomach and hairline. Itchy but does not look like shingles. Took acyclovir for a week after diagnosis. Still getting some red spots, but no blisters. Could this have been some kind of reaction to radiation?
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Hi. Me and my husband are planning to have baby. I was suppose to get my period on 31st August and i didnt. We did home pregnancy test i.e on 9th and 16th of September and it came out negative. We went to see gynea on 16th September and did blood test and it came out negative as well. Doctor prescribed me Primolut Nor 2 tablets a day for 2 days for the period. And uptil now, 24th September, I still havent got my period. Whats happening?
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This is a question for a podiatrist -- I m a pediatrician and saw a 2 year old today with a painless bump on the bottom of his foot close to his heel, on the medial side; his other foot had a similar bump, but not so pronounced. I assume this is a normal finding, but have no idea what it is. Any thoughts?
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Hi, muay I answer your health queries right now ? Please type your query here... both lungs are hyperaeted with low-set diaphragm, Hazed and fibrotic densities are seen in the right upper lobe with intervening lucencies. The right interlobar fissure is tickened.Heart is not enlarged. Costopheric sulci are normal. thank you
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My daughter is 13 years old and suffers from chronic abdominal pain . We have kept food diaries, cut out dairy, taken Lactaid, been to counseling thinking it was stress related. Nothing works. Sometimes constipation, but lately, a lot of diarrhea . We had labs checked to rule out Celiac disease and a host of others. The only abnormal level was low vitamin d . Will supplementing the vitamin d take her pain away? I was told her PCP will not refer to a GI specialist unless 2 or more of these labs were abnormal...
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Dear Doctor, My BP a month ago was 136/104 my doctor advised me to have Eritel 40mg tablet once daily. last week my BP was 135/80, should i continue this tablet i,m asportsmanand rearely take any tablets, im bit confused to see my doctor need your opinion please. pl reply at WWW.WWWW.WW
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What is the next structure that glomerular filtrate enters after passing through the thick ascending limb in the nephron?
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Q:An 8-year-old girl presents to the psychiatrist to discuss the recent divorce of her parents. The girl explains that her mother is the most caring and loving mother anyone could ever have and that she will be spending the majority of her time with her mother. On the other hand, she exclaims that her father is an evil person and hates him. Which of the following ego defenses is best demonstrated by this girl?? {'A': 'Acting out', 'B': 'Denial', 'C': 'Projection', 'D': 'Regression', 'E': 'Splitting'},
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I hit my head yesterday. I have a headache still; it gets worse with movement. I'm also dizzy, off-balance when I walk, and feel nauseous when I move too quickly. I haven't been to my doctor, but I am a nurse and I am scheduled to work tonight. I am having some concentration difficulties and wondering if I should go to my doctor for an excuse for work, or if I should just push through and hope for the best.
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INTRODUCTION: Over the last 20 years (2000-2019) the partners of the Global Polio Eradication Initiative (GPEI) invested in the development and application of mathematical models of poliovirus transmission as well as economics, policy, and risk analyses of polio endgame risk management options, including policies related to poliovirus vaccine use during the polio endgame. AREAS COVERED: This review provides a historical record of the polio studies published by the three modeling groups that primarily performed the bulk of this work. This review also systematically evaluates the polio transmission and health economic modeling papers published in English in peer-reviewed journals from 2000 to 2019, highlights differences in approaches and methods, shows the geographic coverage of the transmission modeling performed, identified common themes, and discusses instances of similar or conflicting insights or recommendations. EXPERT OPINION: Polio modeling performed during the last 20 years substantially impacted polio vaccine choices, immunization policies, and the polio eradication pathway. As the polio endgame continues, national preferences for polio vaccine formulations and immunization strategies will likely continue to change. Future modeling will likely provide important insights about their cost-effectiveness and their relative benefits with respect to controlling polio and potentially achieving and maintaining eradication.
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When i was small that time my lips was in pink colour, now it has been changed to brown colour. How to get back my old lip colour. Could you please suggest me a way to change it to normal colour. Could you please explain what would be the reason for colour change
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Hello! My son (5 years old) has a rash that appears like bites all over his legs and arms. I have two other children that are completely fine with not one bump on them. I took him to the doctor this morning (the doctor from a distance said it was scabies and prescribed a cream). I immediately took him to the dermatologist that disputed that stating it s bug bites. I feel there is something more only for the reason I am with him constantly (with the exception of school). What else could it be?
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Hi, i just noticed yesterday my one year old son has a small moveable lump, smaller than a pea, on his forehead. He bumped his head in roughly the same area about two weeks ago and had quite a bruise- I am not sure if this would be related. Should I be concerned?
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before 2 years i hve misscariage 3 month,then my dr are not recomend d n c.last 1 year i want to conceive bt m fail to get pregnant.my dr says i hv pcos problem i use ivf treament and other more bt m not pregnant.now plz tel me what i can do m very disappointed,plz help me....plz saira
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Hi, I have been experiencing a tingling sensation at the top of my penis , I do not feel it all the time, when I press against the urine pipe I can feel it. I have had more than one case of anal discharge , however both times when my bowels were pretty messed up due to alcohol and food. My doctor gave me Trimethopin which i have taken but the symptoms are still there. I did a urine test and there was pus cells found inside but said there was no infection. They want me to take another one, however I leave the country soon. What do you think it is?
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Q:A 15-year-old boy is referred to a child psychologist because of worsening behavior and constant disruption in class. He has received multiple reprimands in the past 6 months for not doing the homework his teacher assigned, and he refuses to listen to the classroom instructions. Additionally, his teachers say he is very argumentative and blames other children for not letting him do his work. He was previously well behaved and one of the top students in his class. He denies any recent major life events or changes at home. His past medical history is noncontributory. His vital signs are all within normal limits. Which of the following is the most likely diagnosis?? {'A': 'Antisocial personality disorder', 'B': 'Attention deficit hyperactivity disorder', 'C': 'Conduct disorder', 'D': 'Major depressive disorder', 'E': 'Oppositional defiant disorder'},
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Hi I have been on hrt for 8yrs it was changed from estradol 11 months ago to elleste after 5 months on this I got gallbladder disease so it was removed now 6 months later my hot flushes came back I went to the go had blood test and now I need to go for a scan on my liver as the blood results showed abnormal things in my liver is this because of the elleste solo 2mg as I dont drink and I am only 33yrs old
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What is Grade 1 follicular lymphoma characterized by?
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I have an itchy rash on torso, inner left thigh and raised (non itchy) bumps on both sides of my face. I have had Hep C for many years and a liver biopsy 5 years ago came out excellent. Could the rash be a symptom of Hep C - meaning it's screwing w/my immune system by creating autoimmune types of symptoms?
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Hello doctor, I am having -9 spherical and -2 and -1.5 cylindrical power in my eyes. I have a border line eye pressure. Doctor said I cannot take laser or ICL surgery but can have ReLex Smile for that power. But it also needs some cornea tissues which is a risk factor for glaucoma. I do not know what to do now? Which treatment is better for me and the doctor just gave normal lubricant drops? Is there any treatment for me for refractive surgery by controlling eye pressure?
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i feel down quite alot, but overall i am a happy person. just recently ive been down in the dumps and crying over little things, but once ive started i will feel like that for the whole day. it can be over the slightest thing, and il just be in tears. i dont understand why, its really getting to me. i cant go out with my friends without thinking of how il be feeling later when i get home. its horrible, have you any advice for me?
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Hello doctor, My fiancee and I had unprotected sex a few days back, but I did not ejaculate inside her. Just to be on the safer side, we wanted to use the emergency contraceptive pill. But due to some restriction in the country where we live, Plan B or emergency contraceptive pills are not available. I read that Yasmin, which is used as a regular contraceptive pill can be used as an emergency contraceptive pill at a higher dosage. Can Yasmin be used as an emergency contraceptive pill? And at what dosage?
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Generally, we go to a hospital for two reasons, that is, for a regular check-up for aged people and the other is during health issues. For some cases, we need an Ambulance or any means of transport to reach the hospital when the condition becomes critical. Unfortunately, in such cases, we don’t have any predictive systems which keep track of the health conditions of the people and notifies when the situation becomes abnormal. Therefore, in our paper, we have addressed this issue with the help of a system which keeps track of our health and raises an alert notification to our relatives and the doctors of the nearby hospitals or maybe a family doctor who knows our condition well, in case of any abnormal health condition. The proposed system consists of device trackers and sensors to keep track of data and uses a messaging service to send alert notification. This work can further be improvised to suit the current pandemic situation (COVID—19) which can be used as a tracker for tracing the COVID patients. We can place all the required sensors like temperature sensor, heartbeat sensor, pressure sensor, wearable sensors. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
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i am suffering from penile discharge for the past 1 month. only when i think of sex my penis enlarged and some sticky water comes out of it, i want to consult a doctor is VD specilist is correct doctor for this problem and also tell me is this disease serious or not as i am unmarried and getting married in two months.
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Sickle beta thalassemia (Treatment): Treatment for sickle beta thalassemia is supportive and usually depends on the signs and symptoms present in each person. It is generally recommended that all affected people drink plenty of water; avoid climate extremes, activities that lead to inflammation and extreme fatigue; and stay up-to-date on all immunizations. Because sickle beta thalassemia is associated with a variety of health problems, affected people are usually followed closely by their healthcare provider with regular physical examinations that may include specialized laboratory tests and imaging studies (i.e. chest X-ray, transcranial doppler ultrasound, ECG). Blood transfusions may be prescribed on a regular basis for affected people with a history of or risk factors for stroke and other specific health problems, such as pulmonary hypertension. Hydroxyurea, a drug approved by the U.S. Food and Drug Administration for the treatment of sickle cell disease, can decrease the frequency and severity of pain episodes; reduce the need of blood transfusions; and increase life span. [1] [3] For more information regarding the treatment of sickle beta thalassemia and other sickle cell diseases, please click here.
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i have been unwell for 1 year my mind feels numb i feel barley concous cant think or concentrate constant exhaustiomy brain dosent feel the same anymore dont socilize anymore too tired and detached have had lot of blood work done ct head sczan and tested for addissons disease please help i cant go on like this anymore
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Could you explain what a dental abscess is, please?
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I just came from my ent who viewed a ct of my head for a rather large lump in my jawline. Originally he thought it may be a blocked salivary gland but now sees it is a lump off of the lymph node. I am scheduled for a test next week where he will remove cells and have a specialist look at them. My question is, is there a chance it could be cancer?
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Q:A 32-year-old man who recently emigrated from Somalia comes to the physician because of a 4-week history of fever, cough, and chest pain. He has had a 5-kg (11-lb) weight loss over the last 3 months despite no changes in appetite. His temperature is 38.1°C (100.6°F). Physical examination shows enlarged cervical lymph nodes. The lungs are clear to auscultation. The results of an interferon-γ release assay are positive. An x-ray of the chest shows bilateral mediastinal lymphadenopathy. A transbronchial needle aspiration biopsy of a mediastinal lymph node is performed; a photomicrograph of the specimen is shown. The structure indicated by the arrow is most likely comprised of which of the following types of cells?? {'A': 'Macrophages', 'B': 'Neutrophils', 'C': 'Fibroblasts', 'D': 'Natural killer cells', 'E': 'B cells'},
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My 58 year old wife has advanced PP M.S.( she is now a quadriplegic from it) She just went through a 6 week series of Vancomycin. It ended about 3 weeks ago. She now is having very severe abdominal pain and horrible diarrhea. We were told it may be from the Vanco. What can be done to help her if that is the case?
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respected sir i am 30 years old. my diet is healthy. i am suffering from heart palpertation from past 12 years.but from last one month i am feeling heaviness in the middle of my chest.its like acidity problem. i am jogging(not regular) 2 kilometers with out any problem. kinldy help
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My husband may have hepatitis. His liver enzymes are elevated and he has an appointment with a liver specialist. His gen doc sent his blood work out for more tests. If he has Hep B, does that mean he got is sexually??? She said something about getting it from food maybe. What should I do? I worried that I could have something from him?:(
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What medical condition can occur in individuals with recent abortion who develop fever and foul-smelling vaginal discharge?
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My boyfriend has runny, milky semen. Its rarely thick and cant be seen at bottom of toilet after I urine. Im trying to figure out why this is? My other 4 sexual partners in my lifetime have always had thick, clumpy and when I urinated it would drop into the toilet. could this be why Im not conceiving?
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I am 22 years old, and I think that I am suffering from ADHD. I am constantly forgeting appointments, and I spend more time looking for stuff than actually using it. I can't concentrate on one thing very long and I am always waiting until the last minute to do everything. My thoughts are everywhere and it stressed me out. I has gotten worse since I have began my job, it is hard for me to get anything done at work because I can finish anything or sit still. What should I do?
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BACKGROUND: Rheumatoid arthritis (RA) is a systemic autoimmune disease. The combination therapy of methotrexate (MTX) and Janus kinase inhibitor (JAKi) is commonly used. Patients with RA are at increased risk of malignancy, however, it remains unclear whether the combination therapy is associated with a higher risk. OBJECTIVE: To assess the malignancy risk among patients with RA receiving combination therapy of JAKi and MTX compared to MTX alone. METHODS: PubMed, Cochrane and Embase were thoroughly searched for randomized controlled trials (RCTs) in patients with RA receiving JAKi and MTX, from inception to July 2020. Primary endpoints were malignancy events, Non melanomatous skin cancer (NMSC) and malignancy excluding NMSC and secondary endpoints were serious adverse events (SAE), deaths. Risk ratio (RR) and 95% CI were calculated using the Mantel–Haenszel random-effect method. RESULTS: 659 publications were screened and 13 RCTs with a total of 6911 patients were included in the analysis. There was no statistically significant difference in malignancy [RR = 1.42; 95% CI (0.59, 3.41)], neither NMSC [RR = 1.44 (0.36, 5.76)] nor malignancies excluding NMSC [RR = 1.12 (0.40, 3.13)]. No statistically significant difference between the two groups for SAE [RR = 1.15 (0.90, 1.47)] and deaths [RR = 1.99 (0.75, 5.27)] was found. CONCLUSION: The adjunction of JAKi to MTX is not associated with an increased risk of malignancy when compared to MTX alone. There is no increased risk of SAE and deaths when compared to MTX alone in patients with RA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13317-021-00153-5.
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Q:Dr. Ryan is a psychotherapist in a small town. She receives a phone call from a man she was sexually involved with several years ago. The relationship lasted only three months and ended amicably. The man is now married and is having problems unrelated to their past relationship. He has called to see if he can begin seeing Dr. Ryan in therapy. Dr. Ryan should:? A:see the man only if she determines that their past relationship will not interfere with her objectivity.;B:see the man only if their relationship ended more than two years ago and she determines that it will not interfere with her objectivity.;C:see the man but discuss the potential for conflicts with him before beginning treatment.;D:refer the man to a colleague.
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Hello, Recently I am suffering from cold and I got a minor swelling near my eye. I took cold and flu tablets and allegra medicine. I often get dust allergy and sneezing whenever it gets worst doctor has advised me to take allegra. Please help me with your recommendation s
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hello i am 30yrs old i have a 6yrs old son i want another child iam trying since from last 3yrs but not succeded.There is a little problem with my husband semen he is of 31yrs my periods are normal i had an abortion also before 5yrs.Plz suggest me some way
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I am in my 2nd bout of chemo, taxol, avastin and carboplatin. 1st bout not too bad a few days of tiredness, fatique and stomach pain, loss of hair. 2nd bout most the same but stomach pain is presistant and having bowel movement quite often, is this common? I have non-small cell lung cancer
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Patient: Male, 9-month-old Final Diagnosis: Newly diagnosed ITP Symptoms: Petechiae on the forehead • cheeks • mouth • extremities. The patient is febrile, had rhinorrhea for three days previously. The patient is pale, weak, cannot drink Medication: — Clinical Procedure: The patient had immunizations of the Measles-Rubella vaccine 19 days before. Physical examination: Eye, ENT, and mouth, no abnormalities. Heart and Lungs within normal limits. Abdomen: there was no organomegaly – there neither lymphadenopathy nor a congenital anomaly Specialty: Hematology • Infectious Diseases • Pediatrics and Neonatology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Immune thrombocytopenia (ITP) is rare in infants under 1 year old. Bleeding often occurs when the platelet count is <20 000/uL. The disease can progress because of accompanying COVID-19 disease. CASE REPORT: A 9-month-old boy, weighing 8.5 kg, came to the hospital with petechiae on the forehead, cheeks, mouth, and extremities. The patient had rhinorrhea for 3 days previously and was febrile, pale, weak, and could not drink. He had the measles-rubella vaccination 19 days prior. Physical examination showed no abnormalities of the eyes, ears, nose, throat, and mouth. Heart and lungs were within normal limits, with no organomegaly, lymph-adenopathy, or congenital anomaly of the abdomen. Laboratory examination showed hemoglobin, 12.7 g/dL; leukocytes, 7420/uL; platelet count, 16 000/uL; and hematocrit, 37.9%. Erythrocyte sedimentation rate was 14 mm at 1 h and 21 mm at 2 h. Peripheral blood smear showed normal RBC morphology, normal leukocytes, and few platelets. IgG was reactive and IgM was nonreactive on rapid antibody test. RT-PCR was positive for SARS-COV-2. Chest-X-ray showed pneumonia. The diagnosis was newly diagnosed ITP with COVID-19. Patient was treated with 30 mg/kg body weight/day of IV methylprednisolone for 3 days (250 mg); then 20 mg/kg body weight/day (175 mg) orally for 4 days in 3 divided doses. Azithromycin 100 mg/day, zinc 20 mg/day, and vitamin C 50 mg/day orally were also given. CONCLUSIONS: COVID-19 screening is highly recommended during this pandemic to identify it as a potential cause of childhood ITP. Megadose methylprednisolone had an excellent response in alleviating ITP with confirmed COVID-19 in an infant.
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hi,i m hajra 30 yrs old, got married 4 years back,i have been operated once for left ovarian on 15.07.2010 and that was removed and also tubercular infection was detected in pelvic region,the course of t.b.has been completed but after 6 months the cyst recurred again on my right as well as left ovaries and both are 7.5 cm of size,i have no child and i dont want to be operated again,can homeopathic remedy is available for me?
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Hello sir , i am in complte state of shock as yesterday only i came to know thea i have hapetites b postive,, my famly phiscian advsed me to see gasto specialist immediately, i am a 24 year old working professional and lives in mumbai, having made an intensive search about the hapetites b in the interet i know that it cant be fully cured and the cost of treatment in allopathy is almost unaffordable for me which also has lot of side effects, i have come to know about the drug named"virohep", could u please advise me what should i do now, its jst the beginning of my career and i have caught this deadly virus which is goin to remain with me forever....pls help
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sir i am a 37 year old female ,i have asthmatic problem for past 10 years, past three days i have throat pain and respiratory problem,i cant breathe freely. from yesterday night it has increased and i had severe head ache. from morning i feel feverish and body ach too. is this seem to be a symptom for swin flu please answer me immediately becos i have a 10 year old son.
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I have a pea-sized lump in between my shoulder and neck. (left side) I asked my doctor about it months ago, and she said that it's nothing to worry about it will go away over time. It's been almost a year since I've had it. It looks like its filled with puss...there is no pain though. I've tried putting a face cloth dipped in hot water on it to try and drain it. But it doesn't do anything. Should I be worried?
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My son broke his tibia down at ankle last summer at age of 14.. He is now in football this year and states that his calf is tight and really hurting him. feels like shin splints. He also grew 5 inches this past summer and the break was partly in the growth plate by the ankle.
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Animal and human models underline that tubular epithelial cells are susceptible to apoptosis and injury may contribute to organ failure [19, 20].
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My grandmother had brain hammage 5hours back.her rights side is paralized and on the leftside shes constantly having very severe stretches, therewas a leakage but leaking is stopped,but these effects are still very high, wat are the chancesin such cases?
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my gf is pregnet and told me she has clamidia and said i had to of given it to her...i have no symtems what so ever! ive been with her for almost six months and this just came up...but my ex-girlfriend befor her told me she had to take pills because she contracted it from some one....that was in july and now its january? could i be a carrier and have no symtomes?????
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On Saturday I got a diffuse rash (started with whelps and then just turned into a rash, very itchy). Sunday the rash was a little worse. Monday the rash was much better but my hands were EXTREMELY swollen (skin was shiney they were so swollen). I ve also had a headache for over a month (don t know if this is related). Anyways, today (wednesday) my daughter (5 months old) is starting to break out with the same rash. I m very concerned. I took her to the pediatrician yesterday because she s been EXTREMELY fussy and they dx her w/ otitis media and gave her an antibiotic and ear drops (neither of which are helping). Today she also will not eat. PLEASE HELP!
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Yes, thank you. Which Hepatitis comes from eating contaminated shell fish? For instance, I had hepatitis fromeating raw oysters that had come from warm waters, when later I was hospitalized and diagnosed with hepatatitis.Was it A, B, C, ? I need to know so that fill out medical forms correctly. Could you please answer for me?
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Dear Sir/Madam, I am in a confusing situation as me and my girlfriend had unprotected sex once out of the three sessions we had. As it was for the first time for both of us its been a bit confusing situation for us as we used protection during two of the sessions,but couldnt opt for any in one of the sessions. Still we manged to make use of ECP unwanted 72 just 2 hours after we had intercourse.I didnt ejaculated during either of the three days,but even after taking the unwanted 72 pills her periods are delayed.We had intercourse on 1st, 4th & 5th of December 2013 from which we didnt use protection on the 4th of December but managed to opt for emergency contraceptive pill. My girlfriend was expecting her periods on the 8th of December but even after four days she didnt have her periods yet. We both need things safe so we want to make sure what are the chances of her being pregnant and what are the possible causes for her periods to get delayed and are things to be worried of yet...To be honest i love my girlfriend and wouldnt want her to go through things such as abortion,so hopefully i expect things to be safer for her...Please help...
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hi, i have sickle cell disease and developed swollen lymph nodes in the neck. recently i underwent an incision biopsy and it was found that the swelling was not cancerous, neither was it caused by TB. Do I need to do further tests? Has it got anything to do with sickle cell disease?
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Q:A 36-year-old female presents to clinic inquiring about the meaning of a previous negative test result from a new HIV screening test. The efficacy of this new screening test for HIV has been assessed by comparison against existing gold standard detection of HIV RNA via PCR. The study includes 1000 patients, with 850 HIV-negative patients (by PCR) receiving a negative test result, 30 HIV-negative patients receiving a positive test result, 100 HIV positive patients receiving a positive test result, and 20 HIV positive patients receiving a negative test result. Which of the following is most likely to increase the negative predictive value for this test?? {'A': 'Increased prevalence of HIV in the tested population', 'B': 'Decreased prevalence of HIV in the tested population', 'C': 'Increased number of false positive test results', 'D': 'Increased number of false negative test results', 'E': 'Decreased number of false positive test results'},
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I have been for a smear test today and the nurse found a polyp/s I can't even remember much of what she said as I am very scared of surgery and as soon as she said I'd have it removed I nearly had a panic attack of which I started suffering from 4 years ago when I had to have surgery for a different matter. My doctor is on holiday so I was unable to get reassurance from him so really I would just like to know the ins and outs of what happens at the time of removal and also if it is found to be cancerous. Thankyou.
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I have had left knee replacement done twice, the last time being Feb. 2013. My knee still hurts when walking or standing and my lower leg and ankle area swell and hurt a lot. Also my left leg hurts down the front part of my leg into the ankle area. It is hard to walk or stand for any length of time due to the pain. What might be the cause and what can I do to help alleviate the pain. Even at night in bed, my unoperated leg aches like crazy.
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What is the name of the enzyme responsible for breaking down triglycerides stored in adipocytes during lipid transport?
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Girlfriend has a 4cm cyst that was found on her ovary, after which she was told to stop her birth control to get her period to see if the cyst diminished. Now she has missed her period for a month, yet when taking pregnancy tests they indicate she is not pregnant.
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I have a compression fracture C3 and a crush fracture C4/C5. the pain in my neck is unbearable. I find if I look up to say hand a light to my husband, next thing I know I am on the floor, dry retching. I have no recollection of hitting the floor Is it best to put replacement disks in C3/4 and C4/C5 or fuse my neck and have little or no free movement in my neck? PSHx disc replacement L4/5 and L5/S1, I was part of the trial of the procedure 14 years ago. I am Leidan Factor 5. Have had 6 DVT,s and X2 PEs. I also suffer from pheripheral neuropathy of both lower limbs, up to 5 cms past my knee caps. Currently I am taking arava [chemo drug] for auto immune arthritis and IVIG for Tx of neuropathy. The immunologist I am under does not know if it will work. Based on this I see myself as a Lab rat. Any thoughts???
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i am 41 and have recently had vulva itching which i have been treating with vaginal itch cream. about 2 weeks into this i noticed the vulva area had white peeling skin and i have a small area on my lip area that is a bit sore and was irritated after sex. i am married and have had only 1 partner in the last 25yrs. i was diagnosed with HPV as a teenager but haven't had any abnormal pap tests since then.
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my husband has been told that he has arthritis in his foot joint. His shoulder and back have been hurting also. now he has a knot on his finger. he can t sleep with out taking a bunch of pain meds. sometimes that doesnt even help. he can t get into an arthritis dr. until july 22. don t know what to do for him. he s in constant pain. it seems like it keeps spreading. don t like him taking so much pain medication. don t know where to start.
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hi, i needed an expert opinion regarding diagnosis and cure of \"photo-dermatitis\" i.e. being allergic to prolonged exposure of sun-rays excaberated by dust and sweat.
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In the 20th century, the development, licensing and implementation of vaccines as part of large, systematic immunization programs started to address health inequities that existed globally. However, at the time of writing, access to vaccines that prevent life-threatening infectious diseases remains unequal to all infants, children and adults in the world. This is a problem that many individuals and agencies are working hard to address globally. As clinicians and biomedical scientists we often focus on the health benefits that vaccines provide, in the prevention of ill-health and death from infectious pathogens. Here we discuss the health, economic and social benefits of vaccines that have been identified and studied in recent years, impacting all regions and all age groups. After learning of the emergence of SARS-CoV-2 virus in December 2019, and its potential for global dissemination to cause COVID-19 disease was realized, there was an urgent need to develop vaccines at an unprecedented rate and scale. As we appreciate and quantify the health, economic and social benefits of vaccines and immunization programs to individuals and society, we should endeavor to communicate this to the public and policy makers, for the benefit of endemic, epidemic, and pandemic diseases.
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hello, I have terrible right lower sharp abdominal pain (its getting worse and has been hurting for 4 days) and blood in my urine. Sometimes it looks pink and other times it is red with blood clots. My period was a week ago and i have not had sex since. please help.
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However, serum folate levels were decreased in postadolescent acne patients.
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