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The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).
https://en.wikipedia.org/wiki?curid=53379860
2,244,701
The table below gives an overview of the individual event medal winners at the 2010 Oceania Championships.
https://en.wikipedia.org/wiki?curid=53531349
2,244,702
He played one first-class match for Oxford University Cricket Club in 1869. Below first-class, he had appeared in one county match, for Shropshire in 1868.
https://en.wikipedia.org/wiki?curid=53522699
2,244,703
The 4 substrates of this enzyme are L-lysine, NADPH, H, and O, whereas its 3 products are N6-hydroxy-L-lysine, NADP, and HO.
https://en.wikipedia.org/wiki?curid=14045763
2,244,704
MenB is part of the crotonase fold super family, named after the crotonase fold in their structure. The systematic name for MenB is 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA dehydratase (cyclizing). Other common names include:
https://en.wikipedia.org/wiki?curid=14284464
2,244,705
Thus, the two substrates of this enzyme are dTDP-4-amino-4,6-dideoxy-D-galactose and 2-oxoglutarate, whereas its two products are dTDP-4-dehydro-6-deoxy-D-galactose and L-glutamate.
https://en.wikipedia.org/wiki?curid=14549088
2,244,706
Thus, the two substrates of this enzyme are 1-(5-phosphoribosyl)-AMP and HO, whereas its two products are 1-(5-phosphoribosyl)-5-[(5- and phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.
https://en.wikipedia.org/wiki?curid=14503737
2,244,707
Thus, the two substrates of this enzyme are dimethylallyl diphosphate and (-)-(2S)-naringenin, whereas its two products are diphosphate and sophoraflavanone B.
https://en.wikipedia.org/wiki?curid=14545999
2,244,708
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-Lmethioni ne 3-amino-3-carboxypropyltransferase.
https://en.wikipedia.org/wiki?curid=14546017
2,244,709
Thus, the two substrates of this enzyme are poly-cis-polyprenyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and poly-cis-polyprenyl diphosphate longer by one C5 unit.
https://en.wikipedia.org/wiki?curid=14546149
2,244,710
This enzyme belongs to the phosphofructokinase B (PfkB) or Ribokinase family of sugar kinases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose-6-phosphate 1-phosphotransferase. The members of the PfkB/RK family are identified by the presence of three conserved sequence motifs and their enzymatic activity generally shows a dependence on the presence of pentavalent ions. Pentavalent ions dependency is a conserved property of adenosine kinase from diverse sources: identification of a novel motif implicated in phosphate and magnesium ion binding and substrate inhibition. Biochemistry 2002, 41: 4059-4069.</ref> This enzyme participates in galactose metabolism.
https://en.wikipedia.org/wiki?curid=14681489
2,244,711
Thus, the two substrates of this enzyme are ATP and nicotinate ribonucleotide, whereas its two products are diphosphate and deamido-NAD+.
https://en.wikipedia.org/wiki?curid=14679527
2,244,712
This enzyme belongs to a family of enzymes that transfer aldehyde or ketonic groups. To be specific, this enzyme belongs to the transketolase and transaldolase families. Common names for the enzyme are:
https://en.wikipedia.org/wiki?curid=38621390
2,244,713
Copland landed at Goree, Senegal, and later in The Gambia, and Sierra Leone, studying the tropical diseases. On leaving Sierra Leone, three-quarters of the ship's crew went down with fever; and a gale carried away the masts. Copland then landed and made his way along the coast, sometimes on foot, sometimes in small trading vessels or in canoes, till he reached Cape Coast Castle, where he lived for some months.
https://en.wikipedia.org/wiki?curid=38740261
2,244,714
The journal was established in 1992 as "Postępy Medycyny Klinicznej i Doświadczalnej", obtaining its current name in 1998. The first editor-in-chief was Bogumił Halawa (1992–1997). He was succeeded by Leszek Paradowski (1997–1999). The next editor-in-chief of the journal was Antonina Harłozińska-Szmyrka (2000–2005), followed by Leszek Paradowski (2006–2007), Maria Podolak-Dawidziak (2008–2016), and Maciej Bagłaj (2017–2020). Donata Kurpas is the journal's editor-in-chief since 2020.
https://en.wikipedia.org/wiki?curid=69062921
2,244,715
It consists of a large frame carrying two beams from which two rows of six and two wooden balls, respectively, are suspended from pairs of strings. The instrument was often used with two elastic balls (of ivory) or inelastic balls (of wet clay), of equal or different mass. By changing the parameters of the experiments such as height of fall and mass, one could conduct a systematic investigation of collision-related phenomena. For example, when the row of balls is struck by one of the outermost balls, the row of balls remains motionless and the impulse is fully transmitted to the ball at the opposite end, which rebounds. As it falls back, the cycle continues in the opposite direction. This apparatus was illustrated by Jean-Antoine Nollet in "Leçons de physique expérimentale" (Paris, 1743–1748). In his description, Nollet claims to have merely altered and developed a model previously used by Edme Mariotte. The most sophisticated devices for studying elastic and inelastic collisions were built by Willem Jacob 's Gravesande and Petrus van Musschenbroek.
https://en.wikipedia.org/wiki?curid=52094170
2,244,716
The college was inaugurated on 17 June 2016 and the inauguration was attended by the then Deputy Crown Prince Mohammed Bin Salman himself.
https://en.wikipedia.org/wiki?curid=58980845
2,244,717
Chen was born in Changsha, Hunan, on 15 May 1963, while her ancestral home in Yongxin County, Jiangxi. She received his bachelor's degree and master's degree from Central South University of Technology (now Central South University) in 1983 and 1986, respectively. She received her doctor's degree from Tokyo Institute of Technology in 1999.
https://en.wikipedia.org/wiki?curid=68763632
2,244,718
This research Station was established in 1972 by the Agricultural Department of Kerala. When Kerala Agricultural University was established in 1972, Agronomic Research Station was taken over by KAU. The station was taken over for implementing the Co-ordinated project for research on water management sponsored by ICAR. The water management research scheme started functioning from 1974. This research station is conducting active research in organic fertigation.
https://en.wikipedia.org/wiki?curid=42761752
2,244,719
The House of Sustainability is a modern house made of wood and clay, which serves as a model for sustainable living and building. Its power is supplied by a photo-voltaic system, its heating is produced by a wood pellet heating system. Its water supply is provided by rainwater. The nearby forest is part of the concept.
https://en.wikipedia.org/wiki?curid=42540957
2,244,720
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs.
https://en.wikipedia.org/wiki?curid=15181253
2,244,721
It has 4 triangular faces and 3 square faces, 12 edges, and 6 vertices. It can be seen as a rectified hemi-octahedron or rectified hemi-cube.
https://en.wikipedia.org/wiki?curid=45674269
2,244,722
Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate without oxygen transfer] transferring electrons to a hydrogenase.
https://en.wikipedia.org/wiki?curid=38174925
2,244,723
This is heme-thiolate protein (P-450), which is isolated from the bacteria "Streptomyces exfoliatus" and "Streptomyces arenae".
https://en.wikipedia.org/wiki?curid=38211455
2,244,724
A replacement for the Kite 2 was proposed as the T.32 Gull 4B, but this glider did not reach the hardware stage.
https://en.wikipedia.org/wiki?curid=24071763
2,244,725
It was formerly considered a subspecies of "Acronicta leporina" (both species occur in eastern Russia).
https://en.wikipedia.org/wiki?curid=24016874
2,244,726
Pearce returned to the club for the 1926 County Championship, playing four matches for the club. Pearce's final first-class match came against Somerset. In his nine first-class matches Pearce scored 127 runs at an average of 18.14, with his highest score of 63 coming in the 1923 County Championship against Glamorgan.
https://en.wikipedia.org/wiki?curid=25587082
2,244,727
Currently, it is used industrially to verify, with a high throughput, the concentrations of brominated flame retardants (BFR) in plastics in compliance with European RoHS (Restriction of Hazardous Substances) regulation in place since 2006. The banned molecules include PBB and PBDE, whose concentration should not exceed 0.1% w/w.
https://en.wikipedia.org/wiki?curid=13801080
2,244,728
When Price joined the lab of Carl Moore as a technician, Moore was researching "antagonistic" effects between the male and female sex steroids, testosterone and estradiol in the male reproductive system, with often confusing results. While analyzing this data, Price laid out the principle of "reciprocal influence", now known as negative feedback, where the hormone produced by the gonad could also regulate its own stimulation via its effects on the anterior pituitary. Together Moore and Price conducted experiments to show that gonadal hormones could indeed regulate the anterior pituitary (as well as vice versa), and first published the framework in 1930. The negative feedback framework would later be expanded to include the hypothalamus by Geoffrey Harris, and is currently considered a "cornerstone" of endocrinology. The principles discovered by Price and Moore were later used to design and develop hormonal birth control.
https://en.wikipedia.org/wiki?curid=59479222
2,244,729
At 1918, Sergei Alexandrovich Korolev worked at the Department of Microbiology and Zoology at the Vologda Milk Institute. In 1920, he was elected professor of microbiology. He was engaged in improving the quality of dairy products and increasing shelf life (v1922, 1926). In particular, he proved that the yeast were not the agents of rancidity of butter (as some researchers thought), but on the contrary, they are antagonists of the problem and that most species of yeast occurring in oil retains in its mold. Methods of application of special yeast culture to combat mold oil, widely spread in practice to improve the safety of all types of oil.
https://en.wikipedia.org/wiki?curid=26614981
2,244,730
The main goal of this academic project is the study of the hardware implementation of bio-inspired concepts such as self-repair, evolution, self-replication, learning... following the three main axes defined in the POEtic model:
https://en.wikipedia.org/wiki?curid=15481604
2,244,731
He was married twice: first to Laura Ann Secord, the daughter of Laura Secord and the widow of Captain John Poore, and then to Clara Pigott Strange, the widow of Judge William Dummer Powell.
https://en.wikipedia.org/wiki?curid=43981386
2,244,732
74 of the 75 Liga Gimel clubs participated in this round. Most of the matches were drawn as divisional matches, with the exception of two matches.
https://en.wikipedia.org/wiki?curid=41380911
2,244,733
The conference was originally an advisory body, established in 1976 and governed by Articles D.233-D.233-6 to 12 of the French Education Code, widely revised by Decree No. 2006-428 of 11 April 2006, which broadens the scope. It was then chaired by the law minister in charge of Higher Education.
https://en.wikipedia.org/wiki?curid=31231346
2,244,734
The work is divided into nine sections, as follows: Studies, Profiles, Materials, From the research workshops, Points of view, Book Reviews, Events, Curiosa, and Letters.
https://en.wikipedia.org/wiki?curid=22738221
2,244,735
Due to its hygroscopicity, the anhydrous form is hard to prepare. The anhydrous form is usually prepared by the reaction of lithium hydroxide and ammonium thiocyanate, then the water was removed by vacuum, then the resulting solid was dissolved in diethyl ether, followed by adding to petroleum ether to form the ether salt, then it was heated in vacuum at 110 °C to result in the anhydrous salt. The overall reaction is the following:
https://en.wikipedia.org/wiki?curid=71804759
2,244,736
An ecton consists of individual portions of electrons (10– 10 particles). The formation time is of the order of nanoseconds.
https://en.wikipedia.org/wiki?curid=9953214
2,244,737
He competed for Great Britain alongside his brother at the 2006 Commonwealth Games in Melbourne, putting out a public call for sponsors before travelling. He finished in sixth place in the men's 20 km walk, one place above his brother and two places above fellow British competitor Andrew Penn.
https://en.wikipedia.org/wiki?curid=36465016
2,244,738
There is a metastable high-pressure phase of the monoclinic system, space group P 21/c, cell parameters a = 0.75920 nm, b = 0.54673 nm, c = 0.77022 nm, β = 100.032°, Z = 4.
https://en.wikipedia.org/wiki?curid=70721697
2,244,739
This mountain's toponym was officially adopted in 1961 by the U.S. Board on Geographic Names to commemorate California Institute of Technology (Caltech).
https://en.wikipedia.org/wiki?curid=70887085
2,244,740
The work is centred on the production of news and photo releases that highlight interesting Hubble science results and images. These are often European in origin, and so not only increase the awareness of ESA's Hubble share (15%), but the contribution of European scientists to the observatory. Furthermore, the group produces video releases, innovative educational material, CD-ROMs, brochures, posters, as well as DVDs and museum information kiosks, and much more.
https://en.wikipedia.org/wiki?curid=5259450
2,244,741
"Note: Events that have not been placed on the CCA's list of sanctioned events are listed here. If an event is listed on the CCA's final list for the 2013–14 curling season, it will be moved up to the "CCA-sanctioned events" section."
https://en.wikipedia.org/wiki?curid=39203407
2,244,742
Anguilla and Aruba competed for the first time at the championships. Detailed result lists can be found on the World Junior Athletics History website. An unofficial count yields a new record number of about 524 athletes (293 junior (under-20) and 231 youth (under-17)) from about 20 countries:
https://en.wikipedia.org/wiki?curid=32674474
2,244,743
This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
https://en.wikipedia.org/wiki?curid=16860020
2,244,744
The significant weakness of the O-O bond can be explained by formation of the resonance stabilized alkenyloxyl radical and the strong carbonyl bond, respectively. This reasoning also applies to aryl peroxides. Both compound classes thus have significantly weaker O-O bonds than other peroxides. Because of this weak bond, alkenyl peroxides are generally only postulated as reactive intermediates. An exception is the case of some few heteroarylperoxides, which were long-lived enough to be characterized.
https://en.wikipedia.org/wiki?curid=52506243
2,244,745
His first race of note was when he won a skiff race at the Sackville Beach Regatta on the Hawkesbury River on 24 May 1881. He won this particular race four years in succession. In 1883 he won a professional match race at £10 a side by winning a light skiffs event at Sackville. The following year at the same location he rowed George Solomon for £50 a side in light skiffs over three miles and won. His next major race was in October 1884 over three and a quarter miles and for £200 a side against Neil Matterson, a man Kemp, and Bill Beach, were later to row for the World Title. The race was run in "best boats" i.e. lightweight racing craft. This was Kemp's first race in such boats but he managed to lead for the first half of the race. At this point he became so distressed that he had to stop rowing and thus lost the race.
https://en.wikipedia.org/wiki?curid=22274850
2,244,746
He passed the final law examination in 1875. He was in a partnership with Arthur Fell, as solicitors; it was dissolved in 1897. He died at Leigh Hall, East Grinstead in 1929.
https://en.wikipedia.org/wiki?curid=53522699
2,244,747
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating). This enzyme is also called lysine N6-hydroxylase. This enzyme participates in lysine degradation.
https://en.wikipedia.org/wiki?curid=14045763
2,244,748
It was originally thought that the product of this reaction had an oxygen where the SCoA currently resides, however; new research has shown that MenB only catalyzes the above reaction. There is a different enzyme that cleaves the SCoA and attaches the oxygen.
https://en.wikipedia.org/wiki?curid=14284464
2,244,749
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase. Other names in common use include thymidine diphosphoaminodideoxygalactose aminotransferase, and thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase. It employs one cofactor, pyridoxal phosphate.
https://en.wikipedia.org/wiki?curid=14549088
2,244,750
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase. Other names in common use include PRAMP-cyclohydrolase, and phosphoribosyladenosine monophosphate cyclohydrolase. This enzyme participates in histidine metabolism.
https://en.wikipedia.org/wiki?curid=14503737
2,244,751
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase. This enzyme is also called N8DT.
https://en.wikipedia.org/wiki?curid=14545999
2,244,752
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase. Other names in common use include rubber allyltransferase, rubber transferase, isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase, cis-prenyl transferase, rubber polymerase, and rubber prenyltransferase. This enzyme participates in biosynthesis of steroids.
https://en.wikipedia.org/wiki?curid=14546149
2,244,753
As of late 2007, five structures have been solved for this class of enzymes, with PDB accession codes , , , , and .
https://en.wikipedia.org/wiki?curid=14681489
2,244,754
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:nicotinate-ribonucleotide adenylyltransferase. Other names in common use include deamido-NAD+ pyrophosphorylase, nicotinate mononucleotide adenylyltransferase, deamidonicotinamide adenine dinucleotide pyrophosphorylase, NaMN-ATase, and nicotinic acid mononucleotide adenylyltransferase. This enzyme participates in nicotinate and nicotinamide metabolism.
https://en.wikipedia.org/wiki?curid=14679527
2,244,755
In the biosynthesis of vitamin K, SEPHCHC is involved in the second step of the pathway. The type of reaction is decarboxylating, and to have maximum activity, this enzymes uses the cofactor Mg2+, a magnesium ion. In previous years, it was thought that this reaction led to SHCHC, the product MenH. After further research, we now know that this reaction is a new step in the pathway. The actual product of this enzyme can lose a pyruvate spontaneously.
https://en.wikipedia.org/wiki?curid=38621390
2,244,756
In 1818 Copland returned to England, but shortly started on travels through France and Germany. In 1820 he became a licentiate of the College of Physicians of London, and settled in Walworth. In 1822 he took a house in Jermyn Street. In 1825 he lectured on medicine at a medical school then in Little Dean Street, and somewhat later at the Middlesex Hospital.
https://en.wikipedia.org/wiki?curid=38740261
2,244,757
The journal is abstracted and indexed in Embase, Index Medicus/MEDLINE/PubMed, Science Citation Index Expanded, and Scopus. According to the "Journal Citation Reports", the journal has a 2020 impact factor of 1.727.
https://en.wikipedia.org/wiki?curid=69062921
2,244,758
The agreement for the establishment of MBSC was signed in Washington, D.C. by Badr Al-Asaker, secretary-general of the Mohammed Bin Salman Foundation (MISK); Fahd Al-Rasheed, group CEO and MD of KAEC and vice president of the board of trustees of the college; and Kerry Healey, president of Babson College.
https://en.wikipedia.org/wiki?curid=58980845
2,244,759
She joined the Communist Party in May 1983. Chen taught at Central South University of Technology since 1986, what she was promoted to associate professor in December 1991 and to full professor in September 1994. She also served as dean of Business Administration School from June 1999 to April 2002, and dean of Business School from April 2002 to January 2009. Chen became president of Hunan University of Technology and Commerce, in September 2014, and then party secretary, the top political position in the university, beginning in April 2021. In March 2018, she became a member of the 13th National Committee of the Chinese People's Political Consultative Conference.
https://en.wikipedia.org/wiki?curid=68763632
2,244,760
The House of Sustainability has an exhibition which offers suggestions for environmentally friendly and healthy living and construction. It is the main exhibit. Since the house is located not far from the Franco-German border, the exhibition has information in both German and French. In addition, there are theme weeks, lectures and courses held around the subject of sustainability.
https://en.wikipedia.org/wiki?curid=42540957
2,244,761
It can be realized as a projective polyhedron (a tessellation of the real projective plane by 4 triangles and 3 square), which can be visualized by constructing the projective plane as a hemisphere where opposite points along the boundary are connected.
https://en.wikipedia.org/wiki?curid=45674269
2,244,762
The fuselage was of semi-monocoque wooden construction with plywood skinning throughout over longerons and built up frames, most of which were shared with the Slingsby T.26 Kite 2.
https://en.wikipedia.org/wiki?curid=24071763
2,244,763
The larvae feed on "Populus tremuloides", "Betula papyrifera", "Populus balsamifera" "Alnus rugosa" and "Salix" species.
https://en.wikipedia.org/wiki?curid=24016874
2,244,764
IAMS has also been used to analyze diesel exhaust particles, in ceramic processing and in critical silicon etching during semiconductor manufacturing.
https://en.wikipedia.org/wiki?curid=13801080
2,244,765
Although Price originally came up with the negative feedback theory to explain her and Moore's contradictory data, the framework was termed "Moore-Price theory" and Moore was first author on all published papers. Later, Price would be quoted saying that at that time, "women were not really considered scientifically equal to men", Moore was a "male chauvinist" but "did not realize the depth of his own prejudice". However, Moore and Price had a positive research relationship, and she wrote his memorial biography for the National Academy of Sciences.
https://en.wikipedia.org/wiki?curid=59479222
2,244,766
In 1923–24, S. Korolev, together with the professor G.S. Inihovym and students studied the microbiological and biochemical processes of maturation of a number of hard and soft cheese, produced in the USSR. The work enabled the first time to make a harmonious synthesis of a unified theory of ripening cheeses. Prior to that, this theory put forward a Swiss scientist Freydenreyh, based on studies of only Swiss cheese.
https://en.wikipedia.org/wiki?curid=26614981
2,244,767
Among these three research axes, the main effort of the LSL has been focused to the ontogenetic axis through the Embryonics Project, which aims at drawing inspiration from the development of multicellular living organisms in order to obtain in digital hardware some of their original features, and notably growth and fault tolerance.
https://en.wikipedia.org/wiki?curid=15481604
2,244,768
His son Lionel Herbert Clarke was a prominent Toronto merchant and served as Lieutenant Governor of Ontario.
https://en.wikipedia.org/wiki?curid=43981386
2,244,769
Its president is Jacques Fayolle, Director of Télécom Saint-Étienne. The CDEFI board also consists of three Vice-presidents: Emmanuel Duflos, Director of École centrale de Lille; Jean-Michel Nicolle, Director of EPF; Sophie Mougard, Director of École des ponts ParisTech.
https://en.wikipedia.org/wiki?curid=31231346
2,244,770
Historian Samuel Kassow states that the journal is "one of the world’s most important organs of Holocaust scholarship".
https://en.wikipedia.org/wiki?curid=22738221
2,244,771
The monohydrate has 2 forms, the α form, and the β form; the α form reversibly converts to the β form at 49 °C. The α form has the space group "C"2/"m" while the β form has the space group "Pnam". More info on its crystallography are listed in the table below.
https://en.wikipedia.org/wiki?curid=71804759
2,244,772
In 2008 he was selected for the British team at that year's World Cup in Cheboksary, Russia, having set the fastest 20 km by a British athlete for six years. He donated a year's worth of trainers to an exhibition in Suffolk to mark one year prior the 2012 Summer Olympics in London.
https://en.wikipedia.org/wiki?curid=36465016
2,244,773
Caltech Peak is located in an alpine climate zone. Most weather fronts originate in the Pacific Ocean, and travel east toward the Sierra Nevada mountains. As fronts approach, they are forced upward by the peaks (orographic lift), causing them to drop their moisture in the form of rain or snowfall onto the range. Precipitation runoff from this mountain drains into headwaters of the Kern River.
https://en.wikipedia.org/wiki?curid=70887085
2,244,774
The Hubble Information Centre is headed by the science communication specialist Lars Lindberg Christensen and the lead graphic designer is Martin Kornmesser.
https://en.wikipedia.org/wiki?curid=5259450
2,244,775
"The Dominion MA Cup" (presented by TSN) was contested in the 2013–14 season. The Cup was awarded to the Canadian Curling Association Member Association (MA) who has had the most success during the season in CCA-sanctioned events. Events included the Canadian mixed championship, men's and women's juniors championships, the Scotties, the Brier, the men's and women's senior championships and the national wheelchair championship. Points were awarded based on placement in each of the events, with the top association receiving 14 points and each association under receiving points in decrements of one point.
https://en.wikipedia.org/wiki?curid=39203407
2,244,776
Alkenyl hydroperoxides (R = H) have been postulated as reactive intermediates in atmospheric chemistry. They are formed via ozonolysis of alkenes in the atmosphere and form hydroxyl radicals upon decay, which play an important role in the decomposition of pollutants in the air. During day-time, hydroxyl radicals form predominantly photochemically by irradiation with light; whereas in the dark during night-time, the formation via alkenyl peroxides is believed to be their major source.
https://en.wikipedia.org/wiki?curid=52506243
2,244,777
Over the next two years he won a number of smaller races and handicap events and collected some useful prize money. In 1886, he travelled to England with Bill Beach who twice defended his World Title there. Kemp had no great success in England and returned to Australia where he continued to have wins in some of the local regattas and small match races. It was around this time that Kemp went into an intensive regime to improve his rowing. In 1887 he again meet Matterson on the Parramatta River and won with little effort.
https://en.wikipedia.org/wiki?curid=22274850
2,244,778
MenB is composed of two hexamers in an asymmetric unit, these hexamers are each composed of two trimers in an eclipsed arrangement. Each sub unit of the hexamers has three C terminal alpha helices, and a N terminal spiral core. These sub units come together to form the active site of the enzyme.
https://en.wikipedia.org/wiki?curid=14284464
2,244,779
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .
https://en.wikipedia.org/wiki?curid=14503737
2,244,780
As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , and .
https://en.wikipedia.org/wiki?curid=14679527
2,244,781
The structures reveal a stable dimer-of-dimers association in agreement with gel filtration and analytical studies confirm the classification of MenD in the pyruvate oxidase family. The active site is highly basic with a hydrophobic patch. These features match with the chemical properties of the substrates.
https://en.wikipedia.org/wiki?curid=38621390
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Copland was elected Fellow of the Royal Society in 1833, and of the College of Physicians in 1837. He attained a good practice. Among his patients was Dyce Sombre. In 1845, he was elected as a member of the American Philosophical Society.
https://en.wikipedia.org/wiki?curid=38740261
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Prince Mohammed Bin Salman College of Business and Entrepreneurship was established through an international partnership between Emaar The Economic City, Babson Global (a wholly owned subsidiary of Babson College , US), Lockheed Martin under the umbrella of the Economic Offset Program in Saudi Arabia and the MiSK Foundation.
https://en.wikipedia.org/wiki?curid=58980845
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Its dual polyhedron is a rhombic hemi-dodecahedron which has 7 vertices (1-7), 12 edges (a-l), and 6 rhombic faces (A-F).
https://en.wikipedia.org/wiki?curid=45674269
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The wing was mounted on a narrowed pylon which faired into the cockpit canopy, reducing interference drag between fuselage and wing. A rubber sprung nose skid, landing wheel and sprung tail-skid completed the undercarriage. A large comfortable cockpit with an upright seat was covered by a canopy made from blown plexiglas, providing excellent visibility but sometimes giving a poor fit.
https://en.wikipedia.org/wiki?curid=24071763
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Later in her career, Price studied sexual differentiation and development. She extended the organizational-activational hypothesis, showing that fetal androgens can "masculinize" the brain and lead to male sexual behavior in rodents.
https://en.wikipedia.org/wiki?curid=59479222
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Sergei Korolev is the author of "Technical Microbiology of Milk and Milk Products" (1940), recognized as one of the best books in this branch of science. Also, he co-authored with G. Inihovym the textbook "Chemistry and bacteriology of milk and dairy products" (1923).
https://en.wikipedia.org/wiki?curid=26614981
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An artificial organism endowed with all of the features of an embryonic machine was implemented in the BioWall. The BioWatch, which counts hours, minutes, and seconds, is used to demonstrate the growth and self-repair capabilities of the BioWall.
https://en.wikipedia.org/wiki?curid=15481604
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He won the 20 km race at the Manx Harriers open day on the Isle of Man in February 2011. At the 2011 Enfield Open, Daniel placed second, with his brother coming in first. In preparation for the 2012 Games, he took a training trip to Spain with his brother in January 2012. He was also named one of Colchester's "Olympic Champions". Alongside his brother, he was named part of the British squad for the 2012 Racewalking World Cup in Saransk, Russia. He finished the race in 61st place, with a season's best time of 4:20:49.
https://en.wikipedia.org/wiki?curid=36465016
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Alkenyl peroxides can be formed by acid catalyzed condensation of ketones with organic hydroperoxides or hydrogen peroxide. This has been suggested based on the characterization of the corresponding products of decomposition. Alkenyl peroxides could also occur as unwanted byproducts in the Baeyer–Villiger oxidation when using hydrogen peroxide, which would diminish the effectiveness of this reaction.
https://en.wikipedia.org/wiki?curid=52506243
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Kemp was something of a protégée of Beach or at least a training partner. After Beach had won the World Title (1884) and successfully defended an unprecedented six challenges he decided to retire in late 1887 as undefeated champion and announced he was handing the Title to Kemp. It would appear that Beach had arranged for Kemp to challenge for the Title and under the rules then in place declined to accept the challenge within the regulation three months thereby forfeiting the Title. There was no controlling body for the Title (nor for most professional sport titles of the time) so the arrangement stood despite many of the public believing that Kemp was not good enough and unworthy of the Title. A number of commentators believed the situation was rigged and were outraged at the situation.
https://en.wikipedia.org/wiki?curid=22274850
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The channel formed by alpha helices that can be seen in the middle of the enzyme leads to the active site. This opening exists on both top and bottom of the enzyme, allowing substrates different entry points to the active site, which rests in the middle of the enzyme.
https://en.wikipedia.org/wiki?curid=14284464
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There are many similar structures MenD. Though it is commonly found in "E. Coli", but can be found in other organisms as well. Bacillus subtilis and Mycobacterium tuberculosis are two homologues. All of the organisms share something in common, being that catalyze decarboxylation reactions.
https://en.wikipedia.org/wiki?curid=38621390
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Copland was president of the Pathological Society, but without the respect of some of the practical morbid anatomists who attended its meetings. He was Croonian lecturer 1844, 1845, 1846; Lumleian lecturer 1854, 1855, and Harveian orator 1857. He gave up practice about a year before his death, which took place at Kilburn 12 July 1870.
https://en.wikipedia.org/wiki?curid=38740261
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Prince Mohammed Bin Salman College (MBSC) of Business & Entrepreneurship was launched as a new private, higher education institution for both men and women. It was established through an international partnership between Emaar The Economic City, Babson Global (a wholly owned subsidiary of Babson College, USA), Lockheed Martin under the umbrella of the Economic Offset Program in the Kingdom of Saudi Arabia and the MISK foundation.
https://en.wikipedia.org/wiki?curid=58980845
2,244,796
The cantilever two-part wing had a rectangular centre section and tapering outer sections from approximately ⅓-span. A thickened Göttingen 549 section was chosen for the wing root transitioning to Göttingen 549 at the fourth rib then to NACA 0009 at the tip with 5° wash-out at the tips. Large DFS-style airbrakes opening from the top and bottom surfaces aft of the main spar provided adequate approach control. Ailerons were fitted to the trailing edge over the outer ⅓-span. Constructed entirely of wood with steel fittings the single-spar wings had plywood-covered torsion boxes forming the leading edges, and fabric covering aft of the mainspars.
https://en.wikipedia.org/wiki?curid=24071763
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Following the three levels of complexity defined in the Embryonics Project, the BioWatch has been hierarchically designed: The entire watch can be seen as an organism composed of six cells, each of which is dedicated to the calculation of one digit: units and tens of seconds, minutes and hours. Each of these cells is itself decomposed in smaller identical units, i.e. the modules of the BioWall, that could be seen as the basic molecules in a real organism.
https://en.wikipedia.org/wiki?curid=15481604
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The radicals formed from alkenyl peroxides can be utilized in organic radical reactions. For example, they can mediate hydrogen atom abstraction reactions and thus lead to the functionalization of C-H bonds, or they can be used to introduce ketone residues by addition of the alkenyloxyl radicals to alkenes.
https://en.wikipedia.org/wiki?curid=52506243
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Kemp was keen to defend his otherwise empty title and to demonstrate his skills to the public. He wanted to prove he was worthy and so accepted a title challenge from Thomas Clifford, a fellow Australian. The race was set down for 11 February 1888 on the Parramatta River, Sydney, over the usual distance of three and a quarter miles and for a stake of £200 a side. Because of the situation more interest was shown by the public for this race that might normally have been the case. Several large harbour steamers were near the course and a large number of spectators lined the various vantage points on the banks. Kemp won the toss and chose the southern side which gave him an advantage. Kemp took the lead at the start and pulled steadily away from his opponent until at the mile point he was in the lead by four lengths. No effort by Clifford made any difference and Kemp crossed the line about six lengths ahead. The time was 23m.47.5s.
https://en.wikipedia.org/wiki?curid=22274850