UniProt ID
stringlengths 6
10
| Protein Sequence
stringlengths 2
35.2k
| Functional Description
stringlengths 5
30.7k
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Q3AM91
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MSSCGVLVVAGTHGNEVNAPWLLQQWQANPDLIDAAGLAVQKVIGNPEALRRRCRYVDRDLNRCFLPEQLEQGASGLEFQRAGELLRLHGPSGEQPCAVAIDLHSTTAAMGNSLVVYGRRPADLALAALVQGALGLPIYLHEADAQQTGFLVESWPCGLVIEVGPVPQGLLNAGVVEQTRLGLESCLRALYQVRQELARLPDALVVHRHLGSRDLPKAENGEPQALVHPELQGRDWQNIASTQAMFRAADGTDRCEAWVGGEIPVFVNEAAYAEKSIAFSLTRREVWPVEPNWLLALKQLLAAA
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H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate Binds 1 zinc ion per subunit. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
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P73211
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MVNSAVRSLAIVGGVHGNERTGVEVVRRWQQKDFARYFPALKCHYFLANPRAIAANRRYINQDLNRCFRPQDRKNPYLMGYEQLRARQLAHQISLAGIDFIVDLHTTTAAMGTTLILNCPHPLLLNLAAYLSAQDEEIRVLQYSPQKDLPYIRGLCELGLTIELGPVPQGVYDPTAIAKTQRTLARILAYLQASTSGNVPAADNCTVYQQIDTIDYPRDEQGQIVAEIAPHIRDYQAIKPGTPLFYHRRGNVTPYQGAATVYPVFIGEAAYVEKGIAMALTQRKTIAI
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H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate Binds 1 zinc ion per subunit. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
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Q10VR3
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MKKINKLAIVGGTHGNEFTGIYLVKKFEEFPELISRRNFDTQTLLANPQGFELVKRYIDTDLNRCFKVEDLENNTSLNYEESRAKFINQMLGPKGNPKFDFILDLHTTTANMGLTIILVNYHPFNLKIATYLSSVEPNLKIYTCFNPEVENTFINSICERGFAIEVGPIAQGILQADLFYKTEKLVQISLDFIEHFNEGKLDHINRDIVIYKHLKVVDYPKTKDGEIVAMIHPQLQGRDYQKLSPGEPMFLTFDNQTIYYQEESPVWPVFINEAAYYEKGIAMCLTKKESIRV
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H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate Binds 1 zinc ion per subunit. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
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Q3MC79
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MNKINRVAIIGGTHGNEFTGAFLVKKFQQFPEVIQKPSFETLTILGNPKAFEAGKRYIEKDLNRCFLTESLQNPNLSSYEDIRAKQIAGVLGEENQPKVDVVIDLHSTTANMGLSIILGNQDPFLLKLCAYLSEINPLVKVCYTIPEKGSNFLRSLNKLGFVIEVGAVAQGVLNAELFQKTEQLIYTILDYVEKYNQGNIPKINNLLSLYKFTGTIDYPRNGNGDIQAMIHPDIQFRDYAPLNPGDPLFLTLDGKAIAYEGTSIVYPIFINEAAYYEKGIAMLFTEKQLINFD
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H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate Binds 1 zinc ion per subunit. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
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Q96M40
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MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLDLSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAAPFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFVRSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
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Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT. Interacts with GLUT4 (By similarity). Interacts with VCPKMT. Interacts with VCP. Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas. A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein. A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).
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Q9CT64
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MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPSEYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVSRSREGPENIVRIAFQLDDGSRLQDAFCSRQTLWELLSHFAQTRERLQQLGEKTPVCVYMRNEVTGRAALQNTTLQSLGLTGGSATIRFVIKQCDTAGKQESIAVRSKAPGSPVSSLSADQASSSTLLPLNSGEFSRGDLNHEGDANTSGTGLEGGPKPTDAQTKQSTSEPASAPFVPFSGGGQRLGGPSASLRPLTSPSANSSKSFSGPGGPSKPKKPKPGEEPQQEPEPPVDRDPVVYHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPTGLYLEPGLLEHTVSPSTADVLVARCMSRASGSPPLLPAPDPVSLESEPIAEDGALGPPEPIQGTAQPVKRSLGKVPKWLKLPASKR
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Enhances VCP methylation catalyzed by VCPKMT (By similarity). Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface. Interacts with VCP. Interacts with VCPKMT (By similarity). Interacts with GLUT4. Ubiquitous.
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Q7WQR6
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MNTPLRVGIVGCGVLANAMAGHLARQPRPVEIVGCLVRDPGRARGALPCHGSWEALLAQRPEVVVECAGQAALAQYAQVILAAGVDLVPASVGALADDALRGALLEAAAAAGARIRIPSGAMVGIDGLAAARHVGVAEVLYRGTMPPVALQRYVSGPLPERGLAFAGSAREAVARFPKNANLTGTIALAGIGFDRTRVEMLIDPDATANVHELLARGEFGDFHARVSGLRISESSPSSRIVAGSLAQAALGSGFLALS
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q7W1T9
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MNTPLRVGIVGCGVLANAMAGHLARQPRPVEIVGCLVRDPGRARGALPCHGSWEALLAQRPEVVVECAGQAALAQYAQAILAAGVDLVPASVGALADDALRGALLEAAAAAGARIRIPSGAMVGIDGLAAARHVGVAEVLYRGTMPPVALQRYVSGPLPERGLAFAGSAREAVARFPKNANLTGTIALAGIGFDRTRVEMLIDPDATANVHELLARGEFGDFHARVSGLRISESSPSSRIVAGSLAQAALGSGFLALS
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q7VS76
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MNTPLRVGIVGCGVLANAMAGHLARQPRPVEIVGCLVRDPGRARGALPCHGSWEALLAQRPDVVVECAGQAALAQYAQAILAAGVDLVPASVGALADDALRGALLEAAAAAGARIRIPSGAMVGIDGLAAARHVGVAEVLYRGTMPPVALQRYVSGPLPERGLAFAGSAREAVARFPKNVNLTGTIALAGIGFDRTRVEMLIDPDATANVHELLARGEFGDFHARVSGLRISESSPSSRIVAGSLAQAALGSGFLALS
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q7WLJ8
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MTHRIAFIGLGAIASDVAAGLLADAAQPCQLAALTRNAADLPPALAGRVALLDGLPGLLAWRPDLVVEAAGQQAIAEHAEGCLRAGLDMIICSAGALADDALRARLIAAAEAGGARIRVPAGAIAGLDYLQAVAGRDDAEVVYESRKPVAAWRAELPGMGIDPDTLAESRTLFSGPAREAALRFPKNLNVAATLALAGIGMTRTRVEVVVDPRARGNQHRIQVRSPLGEMQIELVNAPSPANPKTSWLVAQSVLATIRRHLARFTIG
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q7W850
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MTHRIAFIGLGAIASDVAAGLLADAAQPCQLAALTRNAADLPPALAGRVALLDGLPGLLAWRPDLVVEAAGQQAIAEHAEGCLKAGLDMIICSAGALADDALRARLIAAAEAGGARIRVPAGAIAGLDYLQAVAGRDDAEVVYESRKPVAAWRAELPGMGIDPDTLAESRTLFSGPAREAALRFPKNLNVAATLALAGIGMTRTRVEVVVDPRARGNQHRIQVRSPLGEMQIELVNAPSPANPKTSWLVAQSVLATIRRHLARFTIG
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q7VX83
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MTHRIAFIGLGAIASDVAAGLLADAAQPCQLAALTRNAADLPPALAGRVALLDGLPGLLAWRPDLVVEAAGQQAIAEHAEGCLTAGLDMIICSAGALADDALRARLIAAAEAGGARIRVPAGAIAGLDYLQAVAGRDDAEVVYESRKPVAAWRAELPGMGIDPDTLAESRTLFSGPAREAALRFPKNLNVAATLALAGIGMTRTRVEVVVDPQARGNQHRIQVRSPLGEMQIELVNAPSPANPKTSWLVAHSVLATIRRHLARFTIG
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q7WE57
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MSSREELGVAVAGLGAIGKALANRLARNEVAGCRLSAVSGRDPGRTADFIASLPRPVPAVPLHELPRHADIVVECAPAAVLPQIVEPVLDAGKKVIVLSVGALLEFPELFRKAGSSDGQILVPTGALLGLDAVTAAAEGRIESVKMVSRKPPIGFKGAPILAERNLDIDGLTEPLLLYSGSARAAARGFPANLNVAVALSLAGIGPDETQLEVWADPGVVRNTHTIEVVSDAALLRMTIENIPSENPKTGRITAQSVMAMLRKMSAPVRVGT
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Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. Belongs to the L-aspartate dehydrogenase family.
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Q66I59
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MADKALKVGIVGYGHLGQFLVEKIQSEGAEVGLQLAFVWNRNADKLKDSLPKDLILHDLSDFTQRDTDVIVEVCHPLIVKEFGVRFLSHAHFLVGSPSALSDGQLEQDLRTAAKQQGKTLYVPSGALWGGQDIQKMNDSGTLRALSIRMSKHPSCFRLTGGLLSDWTEGEGRRVLYRGSVAELCPLAPNNVNTMAAAAIAASKLGFHGVTGEIVSDTALADYHVVEVDVTGPDGFSVKTMRQNPAKLGAVTGKATYNSFWSSLLVCKGHGGRVYLC
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Belongs to the L-aspartate dehydrogenase family.
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Q6NZ37
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MADRGPWRVGVVGYGRLGQSLVSRLLAQGPELGLELVFVWNRDPGRMAGSVPPSLQLQNLAALGERRPDLVVEVAHPKIIHESGAQILRHANLLVGSPSALSDQTTERQLLEASQHWDHAVFVARGALWGAEDIRRLDAAGGLRSLRVTMATHPDGFRLEGPLAAAHSPGPCTVLYEGPVRGLCPFAPRNSNTMAAAALAAPSLGFDGVIGVLVADTSLTDMHVVDVELSGPRGPTGRSFAVHTRRENPAEPGAVTGSATVTAFWQSLLACCQLPSRPGIHLC
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Belongs to the L-aspartate dehydrogenase family.
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A0A2U8U2L8
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MPASLPGQDGGGTRTTRPRSQLRAACDSCNKSKTKCPGGNPCPLCQCSGIRCHYSVAHQLGRPKGSKNKRTLMREMQGSLGNGDASGQFQPNRIVTTAQAHISSNPSPVGSQSQQQQHPQQAGQQQQQQQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQQQQHLLPHAFSNTMQNAGTTAAYAGAEKEDSPLAMDDGELFSMLDQTLLMDTMTDEMSDFGQLVPQALPHPMTMPESLTSLLNHDTAFDATQLSNEYSTSSNSKPSTTDDSCMALPTPDSSTTHRPSSSVFGDGHITFSSGTASASRTSASSIVEQQSIPTSPVTVAPMSPAKSSSVPRTLPPATVTPTCTCLPGLVTLICQLEDLRHPPPPRHTSGQHPHQHPASPYSLKCILQGVQLAEEPWAGFARCLDAAGARKRHGAQENTVQDDDGNDHHRHALALYAMSIRIILSSIHKYRIALSMTGQQQRQHNFGDSPEDLDDAASVLVSVGGVQLAGETKSEMIKIAVRLALKQTTAALMRLLECRNRSSSAPSSATMQVAEYSVGHGRFESTAMVRDHPLPHSMSYSSLKTLAGPHTNMITGQDQLEKRENVAGMLSILQYTTKDLIDGANFDWR
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Transcription factor; part of the gene cluster that mediates the biosynthesis of xenovulene A, an unusual meroterpenoid that has potent inhibitory effects on the human gamma-aminobutyrate A (GABAA) benzodiazepine receptor. Expression is significantly up-regulated under xenovulene A producing condition. Does not affect the production of xenovulene A. Xenovulene A is a natural product exhibiting little structural resemblance with classical benzodiazepines yet is able to displace high-affinity ligand binding to the benzodiazepine site of the gamma-aminobutyrate A (GABAA) receptor and could be potentially used as an anti-depressant with reduced addictive properties.
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O49149
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MAEEKHHHHLFHHKKDDEPATGVDSYGEGVYTSETVTTEVVAGGQDEYERYKKEEKQHKHKQHLGEAGALAAGAFALYEKHEAKKDPENAHRHKITEEIAATAAVGAGGYAFHEHHEKKKDHKSAEESTGEKKHHLFG
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Involved in tolerance to aluminum. Regulates the expression of different genes that collectively contribute to the protection of the cell in response to aluminum stress. Induced by abscisic acid (ABA), osmotic stress and salt stress. Belongs to the abscisic acid and water stress-induced protein family.
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Q53JF7
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MAEEKHHHHLFHHKKDDEPATGVDSYGEGVYTSETVTTEVVAGGQDEYERYKKEEKQHKHKQHLGEAGALAAGAFALYEKHEAKKDPENAHRHKITEEIAATAAVGAGGYAFHEHHEKKKDHKSAEESTGEKKHHLFG
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May function in gibberellin signaling pathway downstream of GID1 and SLR1. May be involved in the regulation of plant growth in the basal region of leaf sheaths (Probable). Involved in tolerance to aluminum (PubMed:22676236, PubMed:24253199). Regulates the expression of different genes that collectively contribute to the protection of the cell in response to aluminum stress (PubMed:22676236, PubMed:24253199). Binds to the promoter and regulates the expression of target genes involved in aluminum stress response. Binds to the promoter of STAR1 gene, which encodes an ABC transporter required for aluminum tolerance (PubMed:24253199). Involved in drought tolerance. Plays a positive role in response to drought stress response by regulating abscisic acid (ABA) biosynthesis, promoting stomatal closure, and acting as chaperone-like protein that possibly prevents drought stress-related proteins from inactivation (PubMed:27420922). Expressed in the basal region of leaf sheaths (PubMed:18210155). Highly expressed in stems, and at lower levels in roots, leaf sheaths and panicles (PubMed:24085307). Induced by gibberellin (at protein level) in the nucleus. Induced by abscisic acid (at protein level) (PubMed:18210155). Induced by aluminum in roots and shoots (PubMed:22676236). Induced by abscisic acid (ABA). Induced by drought and cold stresses in leaves (PubMed:24085307). Induced by cold stress, osmotic shock, salt stress, ABA and ethylene (PubMed:27420922). No visible phenotype under normal growth conditions, but mutant plants are hypersensitive to drought stress, and have decreased sensitivity to abscisic acid-induced germination inhibition and oxidative stress-induced growth inhibition. Plants silencing ASR5 exhibit delayed flowering, abnormal panicles, reduced seed number, reduced number of trichomes on leaves, palea and lemma, and exhibit sensitivity to aluminum and drought stress (PubMed:22676236). Plants over-expressing ASR5 exhibit enhanced tolerance to salt stress, osmotic shock and drought stress (PubMed:27420922). Belongs to the abscisic acid and water stress-induced protein family.
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A0A2U8U2M1
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MRRSFLISAALGLSMSTPALAASIQSVLGYLRPTSHHHAPCADDVVLKQSAGSDSAAPDPLPSRVVHNWPNGTWIENISVRPNGNLLVSQSTPRGRVWQVKEPWLDEPKVELAYDFDEWVDRIIGIGETTPDKYVVVGSRFYSLDPQSSQVERTFCAMELDFTKGEKPSARLVARFPHANLLQSVSALPWDRSVVLISDQYLLHPRADWEDLTPGPGQIWRLDTKTGHHEIVMTNYAEMNTTYNHGLDVGINGIKIHGDHLYWINMDTGGAYRVRIDKYGYPTPLNAVPETLGVAEDALWDDFAMHGTRIGEESDDTTMFATSIVNLMAISPENGTIVPLAGVGTSEPMGFPGPTSAQFGRTEKDSHILYVTGKLFNVPPSIRDVVIQGWVRAIDTTGFHF
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Putative hetero-Diels-Alderase; part of the gene cluster that mediates the biosynthesis of xenovulene A, an unusual meroterpenoid that has potent inhibitory effects on the human gamma-aminobutyrate A (GABAA) benzodiazepine receptor (PubMed:29773797). The first step of xenovulene A biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase aspks1 (PubMed:17912413, PubMed:29773797, PubMed:20552126). The salicylate hydroxylase asL1 then catalyzes the oxidative dearomatization of 3-methylorcinaldehyde to yield a dearomatized hydroxycyclohexadione (PubMed:29773797). The 2-oxoglutarate-dependent dioxygenase asL3 further catalyzes the oxidative ring expansion to provide the first tropolone metabolite (PubMed:29773797). The cytochrome P450 monooxygenase asR2 allows the synthesis of tropolone hemiacetal (PubMed:29773797). In parallel, a previously unrecognised class of terpene cyclase, asR6, produces alpha-humulene from farnesylpyrophosphate (FPP) (PubMed:29773797). The putative Diels-Alderase asR5 probably catalyzes the formation of the tropolone-humulene skeleton by linking humulene and the polyketide moiety (PubMed:29773797). Oxidative-ring contractions catalyzed by asL4 and asL6 then processively remove carbon atoms from the polyketide to yield xenovulene A (PubMed:29773797). Secondary metabolite biosynthesis; terpenoid biosynthesis. Expression is significantly up-regulated under xenovulene A producing condition. Xenovulene A is a natural product exhibiting little structural resemblance with classical benzodiazepines yet is able to displace high-affinity ligand binding to the benzodiazepine site of the gamma-aminobutyrate A (GABAA) receptor and could be potentially used as an anti-depressant with reduced addictive properties. Belongs to the eupF Diels-Alderase family.
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A0A2U8U2L5
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MPVTTPTKMATLTTKQMWQTIKDYFGDGFVTGSAPISYNVHTCDMQLQPDSGIHAASDGIHYGVQISEDSMPLFSIMGDTAAPPCTCHRVDEIVKHIDEFLERAPEALPDDGAITSGKPCDTNPDQVSLYAMRDSLSWWVHWGGNLRPEHYWKQIYIGFAAIPDDVQISPREFLDGTYRYLGHTWDDCLSGLEEEGVSPDEIEFANMCMWRQMLTQWLEKADPELLPLLKGKISLMLQYRVLTANTLGCLALFMNATADPKDGPIHYADSSYEMEIASVAQCVTLDMAKEAMGILQGERTEVVAGDRAQRKRELRWIYVRCMQILESQPHAHMLRRYGSAGLHYVPMMDRYLERVSGHTRFPIRDGAARILERFINRAELPKESEDINPNGRSLKVSAKMNGNGQLHHEVNGNAKLHLEAERPDVTTAVG
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Alpha-humulene synthase; part of the gene cluster that mediates the biosynthesis of xenovulene A, an unusual meroterpenoid that has potent inhibitory effects on the human gamma-aminobutyrate A (GABAA) benzodiazepine receptor (PubMed:29773797). The first step of xenovulene A biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase aspks1 (PubMed:17912413, PubMed:29773797, PubMed:20552126). The salicylate hydroxylase asL1 then catalyzes the oxidative dearomatization of 3-methylorcinaldehyde to yield a dearomatized hydroxycyclohexadione (PubMed:29773797). The 2-oxoglutarate-dependent dioxygenase asL3 further catalyzes the oxidative ring expansion to provide the first tropolone metabolite (PubMed:29773797). The cytochrome P450 monooxygenase asR2 allows the synthesis of tropolone hemiacetal (PubMed:29773797). In parallel, a previously unrecognised class of terpene cyclase, asR6, produces alpha-humulene from farnesylpyrophosphate (FPP) (PubMed:29773797). The putative Diels-Alderase asR5 probably catalyzes the formation of the tropolone-humulene skeleton by linking humulene and the polyketide moiety (PubMed:29773797). Oxidative-ring contractions catalyzed by asL4 and asL6 then processively remove carbon atoms from the polyketide to yield xenovulene A (PubMed:29773797). (2E,6E)-farnesyl diphosphate = alpha-humulene + diphosphate Secondary metabolite biosynthesis; terpenoid biosynthesis. Expression is significantly up-regulated under xenovulene A producing condition. Xenovulene A is a natural product exhibiting little structural resemblance with classical benzodiazepines yet is able to displace high-affinity ligand binding to the benzodiazepine site of the gamma-aminobutyrate A (GABAA) receptor and could be potentially used as an anti-depressant with reduced addictive properties. Belongs to the terpene synthase family. Alpha-humulene synthase eupE subfamily.
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O58478
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MPFLPFSYYPFSLEVILMEYPKIVVKPPGPRAKELIEREKKVLSTGIGVKLFPLVPKRGFGPFIEDVDGNVFIDFLAGAAAASTGYAHPKLVKAVKEQVELIQHSMIGYTHSERAIRVAEKLVEISPIENSKVIFGLSGSDAVDMAIKVSKFSTRRPWILAFIGAYHGQTLGATSVASFQVSQKRGYSPLMPNVFWIPYPNPFRNIWGINGYEEPDELINRVLDYLEYYVFSHVVPPDEVAALFAEPIQGDAGIVVPPENFFKELKKLLEEYGILLVMDEVQTGIGRTGKWFASEWFNVKPDMIIFGKGVASGMGLSGVIGRKEIMDITSGSALLTPAANPVISAAAEATLEIIEEENLLKNALEVGEFIMGRLKEIKERFEIIGDVRGKGLMIGVEIVKENGRPDPEMTGKICWRAFELGLILPSYGMFGNVIRITPPLVLTKEVAEKALEIIERAIKDTLTGKVERKVVTWH
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Catalyzes the interconversion of L-alanine and D-alanine, and L-serine and D-serine. Has weak activity with valine and threonine. L-alanine = D-alanine L-serine = D-serine Completely inhibited by hydroxylamine hydrochloride. Optimum pH is 6.5-7.0. Highly stable at high temperatures. Homohexamer. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
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P26474
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MAIKITPDEFSLLIQRLNKKWRVFAPSAEFRGGRFSDTDNIIYQRISGWRDLIWHEKSHMSPNTIIAPITETLFYFDKDTIQIAETDTSPIIIFARACDINAMSRLDYMYLSNGNNSDYSYQLLREHIRFVLIECEESFENCFCVSMGTNKTDCYSAAMRFSDEGALVSIRDPFIEAAIQGLGQEADYTPSFVSENRETVVTPDSVCHDPQKIRDILTHHPLWDAYDSRCISCGRCTTGCPTCTCYSVFDVAYDENPQRGERRRQWASCMVPGFSDMAGGHGFREKPGERLRYRALHKVNDYKARNGIEHMCVGCGRCDDRCPQYIKFSLIINKMTAAVRQALAEEA
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Electron transfer protein for anaerobic sulfite reductase subunit A. Binds 2 [4Fe-4S] clusters. Sulfur metabolism; sulfite reduction. The anaerobic sulfite reductase seems to consist of three subunits. By sulfite. Repressed by oxygen.
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P26475
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MSHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHWGQFVEVSLPRVGEAPISVSDYGDGWIDLLIRNVGKVTSALFTLKEGDNVWLRGCYGNGYPVDTLRHKPLLVVAGGTGVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEMATWRGKHNLVLTLDEGEADDRYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVKMLLQKGLKPEQIWVDYERRMACSVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD
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This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine. Binds 1 [2Fe-2S] cluster per subunit. Binds 1 FAD per subunit. Sulfur metabolism; sulfite reduction. The anaerobic sulfite reductase seems to consist of three subunits. By sulfite. Repressed by oxygen. Belongs to the PyrK family.
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P26476
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MSIDIDIIKARAKNEYRLSKVRGEAMISVRIPGGILPAHLLTVARDIAETWGNGQIHLTTRQKLAMPGIRYEDIDNVNAALEPFLREIEIELCDVQVEDTKAGYLAIGGRNIVACQGNRICQKANTDTTGLSRRLEKLVYPSPYHLKTVIVGCPNDCAKASMADLGIIGVAKMRFTADRCIGCGACVKACSHHAVGCLALKNGKAVKEESACIGCGECVLACPTLAWQRKPDQLWQVRLGGRTSKKTPRVGKLFLNWVTEDVIKQVIVNLYEFEKEMLGGKPIYLHMGHLIDKGGYLRFKERVLRGVQLNPEAMVAERIYWAEDESVARMHLKPAGH
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This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine. 3 H2O + hydrogen sulfide + 3 NAD(+) = 4 H(+) + 3 NADH + sulfite Binds 3 [4Fe-4S] clusters per subunit. Binds 1 siroheme per subunit. Sulfur metabolism; sulfite reduction. The anaerobic sulfite reductase seems to consist of three subunits. By sulfite. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
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B3A0S2
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MTSYDEEAAINPKAVGNKSSLLKYIIGGGVLAVVGVVAVMVSLQVSGNLVKSEANTLAAQSSGAQRGDRLDLDNDDDLEDEIKEIDDKFKKEFDTLLDNVIQEVNKQLKADLNGGATAGGVNNGGDTDESSNDTDEDSNDSDSKDTDSDSKDTDSDSKDSDSNDTDSDSNGSDSKDTDSDSKDSDSKDTDSDSKDTDSDSKDSDSKDTDSDSKDTDSDSKDSDSNDTDSD
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Component of the acid-insoluble organic matrix of calcified layers of the shell (at protein level).
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A7MLT4
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MKKVLALVVAATMGLSAAAFAADNTAAPAPAAAATTTTTAAPAKAPAAKTHHKKSHKKAVEQKAQAAKKHHKKAAEQKPAAEQKAQAAKKHHKKAAAQKPAVEQKAQAAKKHHKKAVKHDAAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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B7URT6
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MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHARKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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B7M9V0
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MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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B7L5E9
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MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAGKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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Q8X783
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MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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B7NUP2
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MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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B7MV44
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MKKVLALVVAAAMGLSSAAFAAETAITPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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B7LZY9
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MKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAGKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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C4ZY59
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MKKVLALVVAAAMGLSSAAFAAETTTTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
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Required for growth and/or survival at acidic conditions. Proteolytic processing gives rise to the active protein. Belongs to the Asr family.
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Q9KHB9
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAKEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGMTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRQEMSEFMTTSGFDYKMSAEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVRIPAEEVTVRFERGHPVALNGQTFSDDVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDPQALMLRDALQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGESVFSPDDRIGQLTMRNLDITDTREKLFNYVESGLIFSGNAGLPQVANPSLQDKSAK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B5YAL9
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MKKEKVVLAYSGGLDTSVAIKWLMQKYSLDVITLTVDIGQGINLDEIKNKAENLGVEKAYVLDLKEEFVKDYIIPAIKSNAMYERVYPLATALSRPLIAKYLVKIAKENGAKYVAHGCTGKGNDQVRIDLGVKALAPDLEIIAPVREWNFSREEEIEYALENNIPIPVSRKSPYSIDENLWGRSIEGGILEDPWQEPPEDIYLWTRFENREPSYIEITFERGVPVELNGVRKDVVEIIEELNKIAGSYGIGRIDHIENRLVGIKSREIYEAPAAIVIIRAHEALEDMVLPRELAHYKKMLEDKYAELVYYGLWFDPFREALQAFMDKTQDRVTGKVKIKLLPWSFSIVGRESPYSLYDHGLATYDKGSTFSTESAVGFIKLFGLQNYLYALKGGNND
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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B8E0N9
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MEREKVVLAYSGGLDTSVAIKWLMQKYSLDVITLTVDIGQGIDLNEIKNKAENLGVEKAYVLDLREEFIKDYIIPAIKSNAMYERVYPLATALSRPLIAKYLVKVAKENGAKYVAHGCTGKGNDQVRIDLGVKALAPDLEIIAPVREWNFSREEEIEYAIENNIPIPVSRKNPYSIDENLWGRSIEGGILEDPWQEPPEDIYLWTKLENKEPSYIEITFEKGIPVKLNGVEKDLVGLIEELNKIAGSYGIGRIDHIENRLVGIKSREIYEAPAALVIIKAHEALEDLVLPRELAHFKRMLEDKYAELVYYGLWFDPFREALQAFMDKTQERVTGKVKIKLIPWSFSIVGRDSPYSLYDHSLATYDKGSTFSTESAVGFIKLFGLQNYLYALKGGKNA
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A8LPE0
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MSAPKKVVLAYSGGLDTSIILKWLQTEYDCEVVTFTADLGQGEELEPARAKAEMMGASAIYIEDLREEFVRDFVFPMFRANAVYEGLYLLGTSIARPLISKRLVEIAEAEGADAVAHGATGKGNDQVRFELAAYALNPDIKVIAPWREWDLSSRTKLIDFAEKHQIPIAKDKRGEAPFSVDANLLHTSSEGKVLEDPAEDAPDYVYQRTVNPEDAPNTPEYIEVGFERGDAVSINGEAMSPATVLTKLNELGGAHGIGRLDLVEGRFVGMKSRGIYETPGGTILLEAHRGIEQITLDRGAAHLKDELMPRYAELIYNGFWFSPEREMLQAAIDASQAHVTGTVRLKLYKGSVRTVGRWSDHSLYSEAHVTFEDDAGAYDQKDAAGFIQLNALRLKLLAARNKRLGK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q9VI41
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MPKETVILAYSGGLDTSCVLKWLLDKQYEVICVLADVGQKEDFTAAEKKALKIGAKKVIVADVKQSFVEDYIWPAVQMGLVYEERYLLGTSLARPCISVALMEVAREYGAKYLAHGATGKGNDQVRFELCAYALKPDLKIIAPWRDVEFCCQFQGRQDLIAYAQQHGIEVSAKPATPWSTDANILHISYESGILEDPNTVAPENLYEMTVDPLTRAPRDPVHLVIQFDRGLPSSVEDLPGGRVYTKPLEMLDFLNKLGGSYGIGRIDIVENRFVGLKSRGVYETPGGTILFAAHQDLEVFALDREVLRTKQVLRDRMADYVYNGFWFSPEAIYARKCIELAEQRVSGKVTVELAPGYCRAIARKAAKDVGALYNEQLVSMDVHGGYVPQDAGGFIAINAVRIREHVRAFGAYDVPTKKN
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A7ZS69
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENMENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B7UJ66
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVSGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B7MB92
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B7LHN6
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENMENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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Q8X9M0
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQMENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B5YS62
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQMENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B7NKP0
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B7N0V6
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B7M079
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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C4ZSR2
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B1XGY3
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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A8A4Y7
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLHSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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A1AG76
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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Q0TCT8
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MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B1XRS6
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MSDIKKAVLAYSGGLDTSVILKWLQDTYGCEIVTFTADFGQGEELEPARAKALQFGIKPENIFIDDLCEEFVRDFVFPMFRANTIYEGEYLLGTSIARPLIAKRQIEIARLTGADSVSHGATGKGNDQVRFELGYYALEPGIKVIVPWREWDLLSREKLMAYAEKHGIPVEMRHKQGGSPYSMDANLLHISYEGRHLENPNAEAEESMWRWTVSPEKAPDAPEIIEIEFKSGDPVAINGKAYKPHELLAELNRIGGMHGIGRLDLVENRFVGMKSRGCYETPGGTILLKAHRGIESITLDREVAHLKDDLMPRYASLIYNGLWWAPERLALQTLIDHTQQAVNGIVRLKLYKGSVSVISRDSANTLFDQNIATFDDDGGAYNQADAGGFIKLNALRMRIAETARRKRAKK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q12D55
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MATILQNLPAGQKVGIAFSGGLDTSAALHWMKLKGALPYAYTANLGQPDEPDYDEIPRKALQYGAEKARLIDCRSQLAAEGIAALQSGAFHITTAGVTYFNTTPLGRAVTGTMLVSAMKDDDVNIWGDGSTFKGNDIERFYRYGLLTNPNLRIYKPWLDQLFIDELGGRAEMSAFMTQAGFGYKMSAEKAYSTDSNMLGATHEAKDLEHLNSGMKIVNPIMGVAFWKDEVEVKREEVTVRFEEGQPVALNGKTFSNTVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLFIAYERLVTGIHNEDTIEQYRDNGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSILNTVSPNLTYKPERLSMEKVEDAPFSPLDRIGQLTMRNLDIVDTRDKLAIYTQAGLLSAGQGASPPQLKNDERK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B4S7R9
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MSKEKIALAYSGGLDTSVMIKWLKDKYDAEIVAVTGNLGQEKEVENLEEKAIATGASSFAFLDLRKEFVESCIWPALKAGALYEDVYPLATALGRPLIAKALVDIALENNCTMLAHGCTGKGNDQVRFEVTFASLAPQLAVLAPLREWEFTSREAEIAYAMEHNIPVSATKKSPYSIDENIWGISIECGVLEDPMTPAPEDAYQITTSPEKAPDKAAVIDIEFEQGVPVALDGKAMEGLDLIVELNKVGAAHGVGRLDMVENRVVGIKSREIYEAPAATILHFAHRELERLTLEKSVFQYKKNVSQDYANLIYNGTWFSPMREALDGFIEATQKTVTGLVRVKLFKGSVTLLGRTSPWSLYNEDLATYTEADTFNHKAAEGFIHLYGLGLKTWSEVKANNS
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A3PFJ6
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MQQVKKVVLAYSGGVDTSVCIPYLKKEYGVSEVVTFVADLGQGEDLELIRQKALNSGASQSIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREISADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAIEYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMKEAPEDIFAMTSSIENSPDSPQEVEIIFKNGFPVGINDESLTPVEIIKKANVLAGEHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVVDFKGIVEKKWGQLVYQGFWFGPLKDSLDSFISSTQTAVNGRVKIRLHKGNAIVIGRMSENNSLYREDLATYSEEDVFNHSLAEGFIYMWGMSNKIWAELNSKTKD
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A2C5I6
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MGKAKKVVLAYSGGVDTSVCIPYLKKEYGVEHVIAFAADLGQGDELDQIKQKAISAGASESLIGNLVKPFIEDFAFPAIRSNALYQGRYPLSTALARPLIAKNLVEIARELNADGVAHGCTGKGNDQVRFDVTIGALAPDLQLLTPAREWGMSREETIAYGEKYGIVPPVSKKTPYSIDLNLLGRSIEAGPLEDPFEMPSEEVFGITSSIADSPNEPEIVDILFENGYPVAINGEAMEPVSLIKKANSLAGKHGFGRLDIIEDRVVGIKSREIYETPGLLLLIKAHQEIESLTLPADLLDTKFRLERQWADLVYKGFWFSPLKEALDGFINYSQKQVNGTVRVRLFKGNVDVIGRKSKENSLYISDMSTYGSEDKFNHKSAEGFIYVWGLPSRIWSWINK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A8G7L2
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MQQVKKVVLAYSGGVDTSVCIPYLKKEYGISEVITFVADLGQGEDLELIRQKALNSGASQSIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREFSADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAIIYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFAMTSSIDNSPDSPLDIEIIFKNGFPVGINDEFLTPVEIIKKANVLAGEHGYGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDIVDFKGIVEKKWGQIVYQGFWFGPLKDSLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYRDDLATYSKDDVFKHSLAEGFIYMWGMSNKIWAELNSKTTD
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A2CE29
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MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVDEVITFAADLGQGDELDPIRLKALDAGASQSLVGDLIEPFVEEFALPAIRANALYEGRYPLSTALARPLIARRLVEVAREVGADAVAHGCTGKGNDQVRFDLAIAALAPDLKVLTPAREWSMSREEAIAYGERCGIPAPVSKKSPYSIDLNLLGRSIEAGPLEDPMVAPPEEVFAMTSSIDAAPSQAQDIEIRFEAGNPVAIDGVRLDSVGLIKEANRLAGRHGFGRLDIIENRVVGIKSREIYETPGLLLLIRAHQELESLTLAADVLRMKRQLEMQWAELVYQGLWFSPLKDALDGFMDRTQIYVNGLVRIRLHKGNAMVIGRSSDTNSLYISEMATYGSEDNFDHRAAEGFIYIWGLPSRLWAAARRG
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A9BDR3
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MEVKKVVLAYSGGVDTSSCIPYLINEYGVEEVVAFAADLGQGDELEPIREKALSAGASECLVDDLVKPFIEDFAFPAIRANALYEGKYPLSTALARPLISKRLVDIAKELEADAVAHGCTGKGNDQVRFDIAIATLAPELKVLTPARQWGMSREEVIAYGERYGIPAPVSKKSPYSIDLNLLGRSVEAGPLEDISLSPPEEVYQITSSIENTPDQSQEIEIIFEGGNPIAIDGVELDPLSLIVLANQLAGKHGFGRIDMIENRVVGIKSREIYETPGLLLLIKAHQELESLTLPADVLRTKSTLETQWADLVYQGLWFSPLKNALDGFIDRTQDEVNGSVKVKLHKGNATITGRSSSQNSLYLPDFSTYGSQDKFKHDNAEGFIYIWGLPSRLWAQSKNK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A2BZ94
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MQHPKKVVLAYSGGVDTSVCIPYLKNEYGISEVITFVADLGQGDDIESISQKALNSGATKSVIGNLVEDFVEKYAFPAIRANALYGEKYPLSTALARPLIAENLVKLARKLNAGAVAHGCTGKGNDQVRFDLAINALGPDLEIITPAREWKMSREEAILYGEKFGIPAPVSKKSPYSIDVNLLGRSVEAGFLEDPMQEPNEEVFAMTSSIDDSPNYPKDIEITFKNGFPIAIGNESLSPLKIIQKVNYLAGKNGFGRIDMIEDRVVGIKSREIYEAPGLLLLIKAHKELESITLNPDVLDFKNLVEKKWAQLVYQGFWFGPLKKALDGFIDATQTSVNGKVKIRLHKGNAIIIGRSSENNSLYREDLATYSKDDIFDHKQAEGFIYMWGMSNKIWAELNSKMNN
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q317T4
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MQQVNKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELIRKKALNSGASKSIIGNLVSSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFAMTSSINNSPESPLDIEIIFKNGFPVGINNEFLNPVEIIQKANVLAGEYGFGRIDMMEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVIDFKGVVEKKWGQLVYQGFWFGPLKESLDAFIASTQTSVNGRVKIRLHKGNAIVIGRISENNSLYREDLATYSQDDVFKHSLAEGFIYMWGMSNKIWAELNSKKID
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q7V9F8
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MGDFQKVVLAYSGGVDTSACIPYLKNEYGVEEIIAFAADLGQGEELEVVRKKALLAGAKESLVDDLIEPFIHDFAFPAIRANALYEGRYPLSTALARPLIASRLVELAREMEAGAVAHGCTGKGNDQVRFDLAISSLAPHLKILTPAREWSMSRQELISYGEKFGIPAPVSKKSPYSIDLNLLGRSIEAGPLEDPFLAPREEVFQITSSIQESPDTPEEIEIQFEAGNPIAINGVTLDPVSIIKKANALAGRHGFGRIDMIENRVVGIKSREIYEAPGLMLLIKCHQEIESITLSADVLRTKVGIERQWADLVYQGFWFSPLKNALDAFIDRTQLDVNGSVKIQLFKGNATIQGRQSYSNSLYLPDIATYSAEDQYDHKSAEGFIYVWGLANRLWASINRDK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q7V3S9
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MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVEEVITFAADLGQGDELDPIRLKALDAGASQSLVGDLIEPFVEQFALPAIRANALYEGRYPLSTALARPLIARQLVEVAREVGADAVAHGCTGKGNDQVRFDLAIAALAPDLKVLTPAREWSMSREEAIAYGERCGIPAPVSKKSPYSIDLNLLGRSIEAGPLEDLMVAPPEEVFAMTSSIDAAPSQAQDIEISFEAGNPVAIDGVRLDSVGLIKEANRLAGRHGFGRLDIIENRVVGIKSREIYETPGLLLLIRAHQELESLTLAADVLRMKRQLEMQWAELVYQGLWFSPLKDALDGFMDRTQTYVNGLVRIRLQKGNAMVIGRSSDTNSLYISEMATYGSEDNFDHRAAEGFIYIWGLPSRLWAAARRG
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q7UZG0
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MQQVKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGDDLEIVRQKALNSGATKSVIGNLVDNFVEKYAFPAIRANALYGEKYPLSTALARPLIAENLVNLARELNADAVAHGCTGKGNDQVRFDLAIHALGPDLQIITPAREWKMSREEAILYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGLLEDPMQEPDEDVFDMTSSINNAPNAPKDVEIIFQNGFPIAIGNEFLSPVEIIQKANSLAGEHGFGRIDMIEDRVVGIKSREIYEAPGLLLLIKAHKELESITLNPDVLDFKNIVEKKWGQLVYQGFWFGPLKQALDGFIDSTQSSVNGKVKIRLHKGNAIVIGRSSQNNSLYREDLATYSKDDIFNHKQAEGFIYMWGMSNKIWAELNSKKNK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A2BTT9
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MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASKSIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPVEIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVIDFKGMVEKKWGQLVYQGFWFGPLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNSKTKD
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q46I72
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MGKANKVVLAYSGGVDTSVCIPYLKEEYGVEHVIAFAADLGQGDELDEIKKKAISAGASQSLIGNLVKPFIEDFAFPAIRSNALYQGRYPLSTALARPLIAKKLVEIARELNADGVAHGCTGKGNDQVRFDVTIGALAPDLQLLTPAREWGMSREETIAYGEKYGIVPPVSKKNPYSIDLNLLGRSIEAGPLEDPFQMPSEEVFGITSSIADSPNEPEIADILFENGYPVAINGEEMEPVSLIKKANSLAGKHGFGRLDIIEDRVVGIKSREIYETPGLLLLIKAHQEIESLTLPADLLDTKSRLERQWADLVYKGFWFSPLKEALDGFINYSQKQVNGTVRVRLFKGNVDVIGRKSKENSLYISDMSTYGSEDKFNHKSAEGFIYVWGLPSRIWSWINK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q48F14
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MADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHNIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWTKSPEDAPNVATYLELTYRNGDIVALDGVEMTPATVLATLNRIGGENGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDELMAKYASLIYTGYWWSPERLMLQQMIDASQAHVNGVVRLKLYKGNVIVTGRKSDDSLFDANIATFEDDAGAYDQADAAGFIKLNALRMRIAANKGRKLF
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q15X83
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MSKKNIKKVVLAYSGGLDTSAIIPWLKENYDCEVIAFAADVGQGDEELEGLREKAIKTGASECYIVDLKDEFVSDYIYPTITTGAVYEGQYLLGTSMARPIIAKAQVEIARKVGADALCHGCTGKGNDQVRFEGTFAALAPELTVIAPWREWDMVSREDLLAYLAERDIKTTASATKIYSRDANAWHISHEGGELEDPWCEPTKEVWTMTVSPEDAPNTPERVEVSFEHGRMVKVNGEALSPYQCLVKLNELAGAHGVGRIDIVENRLVGMKSRGCYETPGGTVMLAAYKALESLVLDKAALKYREQIGLEFSHVMYDGRWFTPLNDALLAGAASFADKVTGDIVVKLYKGQATVTQRRSPNSLYSEDFATFGADDVYDQSHAEGFIRLYSLSSRISALNKEGIPFKNTGIE
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A6V1S1
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MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKARAMGVREIYIDDLREEFVRDFVYPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWKWTASPESAPDAPTYIELTYRKGDIVAIDGKEMTPAQVLTELNRVGGINGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVVVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRSLS
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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B7UVV5
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MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKARAMGVKEIYIDDLREEFVRDFVYPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWKWTASPENAPDTPTYIELTYRKGDIVAIDGKDMTPAEVLTELNRVGGINGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVVVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRTLS
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q02QZ6
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MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKARAMGVKEIYIDDLREEFVRDFVYPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWKWTASPENAPDTPTYIELTYRKGDIVAIDGKDMTPAEVLTELNRVGGINGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVVVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRTLS
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A7IGW4
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MARDVKKVVLAYSGGLDTSVILKWLQTTYKCEVITFTADLGQGEELEPARKKAQLLGIKDENIFIEDVREEFVAEYVFPMFRANAVYEGLYLLGTSIARPLIAKKQIEIARKMGADAVSHGATGKGNDQVRFELGYYALEPEITVIAPWREWDLTSRTRLLEFAEQHQIPIAKDKRGEAPFSVDANLLHSSSEGKVLEDPAEDAPEYVYQRTISPEAAPDEPTIITIAFDKGDAVAINGEALSPATLLTKLNELGKANGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESITLDRGAAHLKDELMPRYAELIYNGFWFSPEREMLQAAIDHSQAYVTGEVTVKLYKGNTTVIGRKSPYSLYNQELVTFEEGAVAYDHRDAAGFIKLNALRLRTLGSRARKISE
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q7ZWM4
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MSQSKGTVVLAYSGGLDTSCILVWLKEQGFDVIAYLANIGQNEDFEEARKKAVNLGAKKVYIEDIRQQFVEEYIWPAVQANAIYEDRYLLGTSLARPCIAKKQVEIAKKEAAEYVSHGATGKGNDQIRFELTCYSLYPEVKIIAPWRMPEFYNRFRGRSDLMEYAKKHNISVPVTPKSPWSMDENLMHISYEGGILENPKNHAPPGLYLKTKDPATSPDEPDILEIEFKKGVPVKVTNTKNKTQHSSSLALFCYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYQAHLDIEAFTMDREMRKIKQQLSQRFAEQIYNGFWYSPECEFVRSCISKSQEMVEGKVLVSVLKGQVYVLGREAPHSLYNEELVSMDVQGDYDPADACGFIKINAVRLKEYHRLQKNKK
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One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1. Homotetramer. Belongs to the argininosuccinate synthase family.
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Q5M8Z6
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MSQSKGMVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQNEDFEAARKKAVNLGAKKVYIEDMRQQFVEEYIWPAVQANAIYEDRYLLGTSLARPCIAKKQVEIAKKEAAEYVSHGATGKGNDQIRFELTCYALYPEVKIIAPWRMPEFYNRFRGRSDLMEYAKKHNIPVPVTPKDPWSMDENIMHISYEGGILENPKNHAPPGLYLKTKNPATSPNEPDILEIEFKKGVPVKVTNTKEKTQHSSALGLFCYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYQAHLDVEAFTMDREVRKIKQHLSQRFAEQIYNGFWYSPECEFVRSCITKSQEMVEGKVLVSVLKGQVYVLGREAPHSLYNEELVSMDVQGDYDPADACGFIRINALRLKEFHRLQKSKKN
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One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1. Homotetramer. Belongs to the argininosuccinate synthase family.
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Q9PEM9
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MSKKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVNEEERDFIEKRAAELGVASHLTVDGGPAIWDGFVKQLVWTGETYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTGMGNDQVRFDLAIKAQGNYTIIAPIREIQKEHTQTRLYEQKYLEERGFGVRAKQKNYTINENLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPADPLTVAIKFVEGEAVAVDGKPLSGPQILMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRFKPHIARKWVELVYEGFFHDPLKTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHILTSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAQVNRSLRS
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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P59606
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MSNKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASHLTVDGGPAIWDGFVKQLVWAGEAYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTGMGNDQVRFDLAIKAQGDYTIIAPIREIQKEHTQTRLYEQKYLEERGFGVRAKQKNYTINENLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPTDPLTVAIKFVEGEAVAVDGKPLSGPQILMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRFKPHIARKWVELVYEGFFHDPLKTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHILTSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAHVNRSLRS
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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D6W209
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MSKGKVCLAYSGGLDTSVILAWLLDQGYEVVAFMANVGQEEDFDAAKEKALKIGACKFVCVDCREDFVKDILFPAVQVNAVYEDVYLLGTSLARPVIAKAQIDVAKQEGCFAVSHGCTGKGNDQIRFELSFYALKPDVKCITPWRMPEFFERFAGRKDLLDYAAQKGIPVAQTKAKPWSTDENQAHISYEAGILEDPDTTPPKDMWKLIVDPMDAPDQPQDLTIDFERGLPVKLTYTDNKTSKEVSVTKPLDVFLAASNLARANGVGRIDIVEDRYINLKSRGCYEQAPLTVLRKAHVDLEGLTLDKEVRQLRDSFVTPNYSRLIYNGSYFTPECEYIRSMIQPSQNSVNGTVRVRLYKGNVIILGRSTKTEKLYDPTESSMDELTGFLPTDTTGFIAIQAIRIKKYGESKKTKGEELTL
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Catalyzes the eighth step in arginine biosynthesis. Also has a catabolic function as the first enzyme of citrulline utilization as nitrogen source via arginine and the reactions involved in the arginase pathway. ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Optimum pH is 7.5-8.0 for the forward reaction and 6.0-6.5 for the reverse reaction. Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Present with 1870 molecules/cell in log phase SD medium. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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A1JTL6
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYDAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVSVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSAQRWVASEITGEVTLELRRGNDYSILNTVSENLTYQPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTRKKLFSYATTGLLSASAEVGLPQVDNNNLTARGLQDKSK
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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A7FJE9
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B2JZQ2
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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Q0WGK5
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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A9R622
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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C4GUW9
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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A4TKI3
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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Q66C31
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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B1JPT9
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MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 2 subfamily.
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Q5NNQ0
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MTEKVKRVVLAYSGGLDTSVILKWLQEHYGCEVVTFTADLGQGEELEPARKKAEMMGIKPEHIFMDDLREEFVRDFVFPMMRANALYEGQYLLGTSIARPLIAKRQIEIARQVGADAVAHGATGKGNDQIRFELGYYALAPDIKVIAPWREWDLNSRSKLIAYAESRQIAVPKDKRGESPFSVDSNLLHTSSEGKILEDPWQEVPDYVYSRTVNPEDAPNTPEIITIDFERGDAIAINGEALSPAELLTKLNELGRKHGIGRLDLVENRYIGMKSRGMYETPGGTILIQAHRGIEQLTLDGGAMHLKDELMPRYAELIYNGFWYSPEREMLQAAIDHSQARVSGTVRLKLYKGSVNVIGRKSPNSLYSEKVVTFEDDAGAYNQQDAAGFIKLNALRLRLLGERNAKGL
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ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Homotetramer. Belongs to the argininosuccinate synthase family. Type 1 subfamily.
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Q22355
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MQVVSSATLPPTVASADLAIVGGRSSDEDVIKYSAIQTIKQEQQQQQQQQSNTALPSYNFPFFNGMQNDFPPNRMLYNDNTMQKSENDHFTGMNLSTSASSSGNSTSSKDQSRRQFYTESSNSSGNGAAATSGSNGSSSSTESKSDVFNISMNAFAATPGSKSEDHNIPSFNMLSSYYTGALKLSNSTSFANPDPYQILGPTSKNLAHSGSGQTQLWQFLLELLSDKRYSEVITWEGTQGEFKLVDPDEVARKWGERKSKPNMNYDKMSRALRYYYDKNIMAKVHGKRYAYKFDFQGIAQALQPPTASHPQDYFNSHAMGRIAPDFSSWTSANYRSLNIAGFNNGSTIFNPSVNYSAFGATGTSNNLSAARAFPLYR
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Transcription factor (PubMed:16584723, PubMed:19287374, PubMed:23788625). Probably binds to DNA sequences containing the consensus motif 5'-CGGA[AT][AG]-3' (PubMed:19287374). Positively modulates expression of dopamine pathway genes, acting as a terminal selector for differentiation of dopaminergic neurons; may act in concert with homeobox proteins ceh-40, ceh-43 and ceh-20 (PubMed:19287374, PubMed:23788625, PubMed:22069471). Required for axon navigation in some interneurons, perhaps acting in the same pathways as basement membrane protein nid-1 and unc-6/netrin (PubMed:16584723). Plays a role in the differentiation of the ventral cord pioneer neuron AVG (PubMed:16584723). Required for morphogenesis of the pharynx (PubMed:16584723). Initially localized only in the nucleus, but later in development, at about the 3-fold stage, expressed elsewhere in the cell body and also in the neuronal projections. Expressed in the A-neurons in the male-specific genital sensilla (simple sense organs) known as rays. Expressed in the embryo in sensory neurons with 6-fold symmetry, probably the inner labial neurons (PubMed:16584723). Expressed between comma and 3-fold stage, diminishing afterwards and absent in larval stages and adults (PubMed:16584723). Expressed in all dopaminergic neurons throughout postembryonic stages (PubMed:19287374). Expressed in a few cells in the pharynx at the 2-fold stage (PubMed:16584723). RNAi-mediated knockdown abolishes expression of tyrosine monooxygenase cat-2 in neurons in the male-specific genital sensilla (simple sense organs) known as rays. Belongs to the ETS family.
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O14061
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MGVPRLGRFLEPFGKPVYFSSYPEVPLNCSLVIDGPSFAFWLWFSQGIVCSDFQGYQKAVLDFHHLLSRLRFKEIEYIFDGGLPFSKHQVRVNRYQQKINDLRSAYINLCVPIAQHVLMGLAKAKVIVCNEEADKYCAFQAKKLDAVILSQDSDFLLYDIDTPHYGYIPLQSLDVTSNGISGRKYRFDEIQKDFHFDLHILAAYLGVEGHPLDLVIDYHNTFEHICKILENSVKDKFIEKLVSKEELTRVHAFYSLNDLKLETSTINTFMWGRVQELLNSQLQPAEIWLPQLLELPSKHCSWLESAPLRLQAYANFSKQMPEFGTEVLEYFRLSDRLSKRLISVDYDYATVCETLDSKFSNWNLPHRLVLWTLRCMKNLNNITATSFLLMHVSLFLGSPMNLQPVEPTQEDIASVSRFIATIYSICMLIFSEDKEQSSISFQEFVSFSPLSSTLNFALFHQAASKLKTGKSPLSIVTDKTTASLTYKMYKDLTNDYSDIYMIMDIWKPKRKRKTKKDQS
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Belongs to the asteroid family.
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P89492
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MAKDILKNQDPKLQAMIVEHSAPAPKEIPMDAPVLKRVARPLRHVKFIPIKSLIFHTKTGPMDFSYEKKIKTPIPKNKIVVRVSNVGLNPVDMKIRNGYTSSIYGEIGLGREYSGVITEVGENLNYAWHVGDEVYGIYYHPHLAVGCLQSSILVDPKVDPILLRPESVSAEEAAGSLFCLATGYNILNKLSKNKYLKQDSNVLINGGTSSVGMFVIQLLKRHYKLQKKLVIVTSANGPQVLQEKFPDLADEMIFIDYLTCRGKSSKPLRKMLEEKKISQYDPVEDKETILNYNEGKFDVVLDFVGGYDILSHSSSLIHGGGAYVTTVGDYVANYKEDIFDSWDNPSANARKMFGSIIWSYNYTHYYFDPNAKTASANNDWIEQCGDFLKNGTVKCVVDKVYDWKDHKEAFSYMATQRAQGKLIMNVEKF
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Lipid raft-associated protein involved in the targeting of PMA1 from Golgi to the plasma membrane (PubMed:7822420, PubMed:11739806). May induce clustering of PMA1, which facilitates partition of PMA1 into lipid rafts after leaving the ER and its transport to the cell surface (PubMed:11739806). Interacts with PMA1.
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D3DM08
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MAEKILENKDPKLEAMTVDHEVSAPKPIPVDEPTLTRVARPLRHVRHIPVKSLVFHSKHGPITFSYENKIKLPISKNKLVVQVNYVGLNPVDMKIRNGYTKPIYGEAGIGREYSGVITHVGDNLTNRWNVGDDVYGIYYHPKLAIGALQSSLLIDPRVDPILMRPKNTLSPEKAAGSLFCLGTALNLLAQLKEKDQLNTESNVLINGGTSSVGMFAIQLLKRYYKVSKKLVVVTSGNGAAVLSEHFPDLKDEIIFINYLSCRGKSSKPLRRMLDTGKVVDYDDFNTLKETEDYTQGKFNVVLDFIGGYDILSHSSSLIHAKGAYITTVGDYVGNYKKDVFDSWDNPSANARKMFGSMLWSYDYSHFYFDPNIKIIPKKNDWIHECGKLLNEGVVDCVVDKVYSWKNFKEAFSYMATQRAQGKLIMKVEGF
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Lipid raft-associated protein involved in the targeting of PMA1 from Golgi to the plasma membrane (Probable). May induce clustering of PMA1, which facilitates partition of PMA1 into lipid rafts after leaving the ER its and transport to the cell surface (By similarity). Present with 937 molecules/cell in log phase SD medium.
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B4T3Z5
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MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. Belongs to the arginine N-succinyltransferase family.
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Q5PHB9
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MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. Belongs to the arginine N-succinyltransferase family.
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A9N277
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MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. Belongs to the arginine N-succinyltransferase family.
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B5BA71
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MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. Belongs to the arginine N-succinyltransferase family.
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B4TUC2
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MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSDELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. Belongs to the arginine N-succinyltransferase family.
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Q8Z6G0
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MRVIRPVEHADIAALMQLAGKTGGGLTSLLANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARVVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPALGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. Belongs to the arginine N-succinyltransferase family.
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Q8ZPV1
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MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
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Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. L-arginine + succinyl-CoA = CoA + H(+) + N(2)-succinyl-L-arginine Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5. By nitrogen and carbon starvation, and arginine, via the ArgR and Crp transcriptional regulators. Belongs to the arginine N-succinyltransferase family.
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