BioMCQA/test_mcq · Datasets at Hugging Face

question_key stringlengths 16 58	relation stringlengths 6 48	question_template stringlengths 29 90	subject_cui stringlengths 8 8	subject_label stringlengths 4 160	correct_object_cui stringlengths 8 8	correct_object_label stringlengths 3 204	opa stringlengths 7 150	opb stringlengths 3 204	opc stringlengths 4 221	opd stringlengths 5 166	cop int64 0 3
C0014869::may_be_treated_by	may_be_treated_by	Which of the following may treat {subj}?	C0014869	Peptic Esophagitis	C0052993	basic aluminum carbonate gel	calcium phosphate / picolinic acid	lithium carbonate / sodium chloride	basic aluminum carbonate gel	ammonium phosphate	2
C0011777::may_prevent	may_prevent	Which of the following may be prevented by {subj}?	C0011777	dexamethasone	C0004096	Asthma	Other Asthma	Childhood asthma	Asthma-like condition	Asthma	3
C0060231::may_prevent	may_prevent	Which of the following may be prevented by {subj}?	C0060231	ferric citrate	C0162316	Iron deficiency anemia	Iron deficiency anemia	Anemia due to protein deficiency	Iron deficiency anemia secondary to chronic blood loss	Other deficiency anemias	0
C0991853::may_prevent	may_prevent	Which of the following may be prevented by {subj}?	C0991853	nicotinamide hydriodide	C1956346	Coronary Artery Disease	Coronary Artery Disease	Renal Artery Disease	Carotid Artery Diseases	Coronary bypass stenosis	0
C0123053::may_treat	may_treat	Which of the following may be treated by {subj}?	C0123053	ibutilide fumarate	C0003811	Cardiac Arrhythmia	Drug induced arrhythmia	Cardiac Arrhythmia	Arrhythmia during surgery	Arrhythmia-Induced Cardiomyopathy	1
C0022489::may_treat	may_treat	Which of the following may be treated by {subj}?	C0022489	kanamycin A	C0085394	Serratia Infections	Sepsis caused by Serratia	Hantavirus Infections	Cecal Infection	Serratia Infections	3
C0812398::may_treat	may_treat	Which of the following may be treated by {subj}?	C0812398	hetacillin potassium	C0022729	Klebsiella Infections	Klebsiella Infections	Klebsiella urinary tract infection	Corynebacterium Infections	Bacterial infection caused by Klebsiella pneumoniae	0
C2757006::mechanism_of_action_of	mechanism_of_action_of	For which drug or chemical is {subj} the mechanism of action?	C2757006	Immunologic Factor Interactions [MoA]	C0556243	propylparaben sodium	icometasone enbutate	propylparaben sodium	fenipentol	butaperazine maleate	1
C1373138::mechanism_of_action_of	mechanism_of_action_of	For which drug or chemical is {subj} the mechanism of action?	C1373138	Transpeptidase Inhibitors	C0007735	cephalothin	cephalothin	cloxazolam	cethromycin	cefonicid sodium injection	0
C2757009::mechanism_of_action_of	mechanism_of_action_of	For which drug or chemical is {subj} the mechanism of action?	C2757009	Nucleic Acid Synthesis Inhibitors [MoA]	C0771588	quinine ascorbate	ascorbic acid buffered	quinine ascorbate	ascorbic acid / dequalinium	ascorbic acid / bee pollen	1
C5205177::molecular_abnormality_involves_gene	molecular_abnormality_involves_gene	Which gene is involved in the molecular abnormality {subj}?	C5205177	ETV Gene Rearrangement	C0812200	ETS Family Gene	ETS Family Gene	FES gene	ADAM Family Gene	XAGE1 Family Gene	0
C1709998::molecular_abnormality_involves_gene	molecular_abnormality_involves_gene	Which gene is involved in the molecular abnormality {subj}?	C1709998	SS18-SSX Fusion Protein Expression	C1420439	SS18 gene	ID2 gene	SS18 gene	ID4 gene	AASS gene	1
C5708027::molecular_abnormality_involves_gene	molecular_abnormality_involves_gene	Which gene is involved in the molecular abnormality {subj}?	C5708027	EZH2 NM_004456.5:c.1936T>G	C1333368	EZH2 gene	HERC2 gene	EGR2 gene	EZH2 gene	ALKBH7 gene	2
C1820119::negatively_regulated_by	negatively_regulated_by	Which entity negatively regulates {subj}?	C1820119	Mitophagy	C3547217	negative regulation of mitophagy	positive regulation of lysosome organization	negative regulation of mitophagy	positive regulation of vacuole fusion, non-autophagic	positive regulation of phagocytosis	1
C2611051::negatively_regulated_by	negatively_regulated_by	Which entity negatively regulates {subj}?	C2611051	brown fat cell proliferation	C2611060	negative regulation of brown fat cell proliferation	positive regulation of type B pancreatic cell development	positive regulation of lens fiber cell differentiation	negative regulation of brown fat cell proliferation	positive regulation of B cell proliferation	2
C0752319::negatively_regulated_by	negatively_regulated_by	Which entity negatively regulates {subj}?	C0752319	MAP Kinase Cascade	C2248527	negative regulation of MAPK cascade	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	positive regulation of protein kinase B signaling	positive regulation of apoptotic signaling pathway	negative regulation of MAPK cascade	3
C4327435::negatively_regulates	negatively_regulates	Which entity is negatively regulated by {subj}?	C4327435	negative regulation of cellular response to manganese ion	C2754488	cellular response to manganese ion	cellular response to insulin stimulus	positive regulation of cellular response to manganese ion	cellular response to manganese ion	cellular response to cytokinin stimulus	2
C1523067::negatively_regulates	negatively_regulates	Which entity is negatively regulated by {subj}?	C1523067	negative regulation of calcium-independent cell-cell adhesion	C1154388	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	negative regulation of leukocyte cell-cell adhesion	negative regulation of homophilic cell adhesion	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	cell-matrix adhesion involved in tangential migration using cell-cell interactions	2
C3157499::negatively_regulates	negatively_regulates	Which entity is negatively regulated by {subj}?	C3157499	negative regulation of Rho-dependent protein serine/threonine kinase activity	C3156573	Rho-dependent protein serine/threonine kinase activity	negative regulation of protein tyrosine phosphatase activity	SRC Tyrosine Kinase Activation Pathway	positive regulation of peptidyl-tyrosine autophosphorylation	Rho-dependent protein serine/threonine kinase activity	3
C2328236::nerve_supply_of	nerve_supply_of	Which anatomical structure has {subj} as its nerve supply?	C2328236	T3 branch to left semispinalis thoracis	C0816124	Left semispinalis thoracis	Set of right semispinalis muscles	Left semispinalis thoracis	Left second interspinalis lumborum	T7 branch to left semispinalis thoracis	1
C2329296::nerve_supply_of	nerve_supply_of	Which anatomical structure has {subj} as its nerve supply?	C2329296	Nerve to depressor anguli oris	C0224113	Depressor anguli oris muscle structure	Entire adductor brevis muscle	Entire second levator costae brevis	Depressor anguli oris muscle structure	Entire levator labii superioris muscle	2
C2333910::nerve_supply_of	nerve_supply_of	Which anatomical structure has {subj} as its nerve supply?	C2333910	Nerve to right rhomboid major	C0507195	Right rhomboid major	Right coracoid process	Right rhomboid major	Entire rhomboid major muscle	Right superciliary arch	1
C0038967::occurs_after	occurs_after	Which of the following occurs after {subj}?	C0038967	Suture granuloma	C0184661	Interventional procedure	Surgical manipulation procedure	Interventional procedure	Physical Treatment Methods	Interventional debulking surgery	1
C0264767::occurs_after	occurs_after	Which of the following occurs after {subj}?	C0264767	Rheumatic mitral stenosis with insufficiency	C0554628	Group A Streptococcal Infections	Streptococcal sepsis	Staphylococcal Skin Infections	group G Streptococcal infection	Group A Streptococcal Infections	3
C2316651::occurs_after	occurs_after	Which of the following occurs after {subj}?	C2316651	Infection of total ankle joint prosthesis	C0188664	Total ankle replacement	Primary hybrid total elbow replacement	Hip joint reconstruction	Total ankle replacement	Reconstruction of ankle joint	2
C3662483::occurs_before	occurs_before	Which of the following occurs before {subj}?	C3662483	Allergic sensitization	C0571821	Multiple electrolyte infusion allergy	Allergy to lithium compound	Topical adhesive allergy	Elastoplast allergy	Multiple electrolyte infusion allergy	3
C5686631::occurs_before	occurs_before	Which of the following occurs before {subj}?	C5686631	Reconstruction using flap	C5768624	Partial myocutaneous flap necrosis	Skin necrosis due to heparin induced thrombocytopenia	Intraoperative open wound of scalp associated with Mayfield head clamp	Avascular necrosis of metatarsal bone	Partial myocutaneous flap necrosis	3
C0184661::occurs_before	occurs_before	Which of the following occurs before {subj}?	C0184661	Interventional procedure	C0274311	Complication of surgical procedure	Complication of acute stroke	Complication of breast implant surgery	Complication of surgical procedure	Surgical Complication	2
C1325422::occurs_in	occurs_in	In which of the following does {subj} occur?	C1325422	extracellular matrix structural constituent	C0015350	Extracellular Matrix	Epidermal basement zone	Extracellular Matrix	Basal Lamina Collagen	Entire connective tissue	1
C1152928::occurs_in	occurs_in	In which of the following does {subj} occur?	C1152928	structural constituent of myelin sheath	C0026973	Myelin Sheath	Electron-Dense Plasma Membrane Layer	Myelin Sheath	Outer Leaflet of the Lipid Bilayer	Meiotic Spindle Apparatus	1
C4328744::occurs_in	occurs_in	In which of the following does {subj} occur?	C4328744	somato-dendritic dopamine secretion	C3893311	somatodendritic compartment	extrinsic component of presynaptic active zone membrane	myelin sheath adaxonal region	axonemal central bridge	somatodendritic compartment	3
C0086418::organism_has_gene	organism_has_gene	Which gene is found in the organism {subj}?	C0086418	Homo sapiens	C1412338	ALDH1B1 gene	ALDH5A1, EX7DEL	ALDH1B1 gene	PCAT1 gene	BCKDHB gene	1
C0458621::part_of	part_of	Which of the following contains {subj} as a part?	C0458621	Entire sinus epididymidis	C0014533	Epididymis	Ligament of epididymis	Epididymis	Adventitia of epididymis	Lobule of right epididymis	1
C0924087::part_of	part_of	Which of the following contains {subj} as a part?	C0924087	Inferior fibular retinaculum	C0929803	Investing fascia of right ankle	Fascia of right shoulder	Superficial fascia of right leg	Investing fascia of pelvic girdle	Investing fascia of right ankle	3
C0448625::part_of	part_of	Which of the following contains {subj} as a part?	C0448625	Tendon of anterior crural muscle	C1269079	Entire lower limb	Entire nervous of limb	Entire median nerve	Entire external oblique	Entire lower limb	3
C0302592::pathogenesis_of_disease_involves_gene	pathogenesis_of_disease_involves_gene	Which gene is involved in the pathogenesis of the disease {subj}?	C0302592	Cervix carcinoma	C0079419	TP53 gene	TP53 gene	TAF6 gene	TPM3 gene	TRAT1 gene	0
C4054911::pathogenesis_of_disease_involves_gene	pathogenesis_of_disease_involves_gene	Which gene is involved in the pathogenesis of the disease {subj}?	C4054911	Fusion-Positive Rhabdomyosarcoma	C1847791	PAX3/FOXO1 Fusion Gene	SS18L1/SSX1 Fusion Gene	MLL/ARHGAP26 Fusion Gene	NUP98/PRRX1 Fusion Gene	PAX3/FOXO1 Fusion Gene	3
C0950121::pathogenesis_of_disease_involves_gene	pathogenesis_of_disease_involves_gene	Which gene is involved in the pathogenesis of the disease {subj}?	C0950121	Denys-Drash Syndrome	C0694898	WT1 gene	TAL1 gene	WFS1 gene	TET1 gene	WT1 gene	3
C2711370::pathological_process_of	pathological_process_of	For which condition is {subj} the pathological process?	C2711370	Parasitic process	C0276893	Infection by Nosema bombycis	Sporothrix schenckii Infection	Capnocytophaga canimorsus sepsis	Infection due to Penicillium mycetogenum	Infection by Nosema bombycis	3
C0009450::pathological_process_of	pathological_process_of	For which condition is {subj} the pathological process?	C0009450	Communicable Diseases	C0276854	Infection by Babesia canis	babesiosis other due to Babesia venatorum	Infection by Babesia canis	Infection by Histoplasma capsulatum, other	Infection due to Penicillium mycetogenum	1
C0745283::pathological_process_of	pathological_process_of	For which condition is {subj} the pathological process?	C0745283	INFECTIOUS PROCESS	C0042636	Vibrio Infections	Cecal Infection	Balamuthia Infection	Parainfluenza Virus Infections	Vibrio Infections	3
C0027651::pathology_of	pathology_of	For which condition is {subj} the pathology?	C0027651	Neoplasms	C0371474	Thoracoscopy, surgical; with excision of pericardial cyst, tumor, or mass	Thoracoscopy, surgical; with excision of pericardial cyst, tumor, or mass	Creation of pericardial window or partial resection for drainage	Pericardiotomy and drainage of effusion	Mediastinotomy with exploration, drainage, removal of foreign body, or biopsy; cervical approach	0
C0033377::pathology_of	pathology_of	For which condition is {subj} the pathology?	C0033377	Ptosis	C0193094	Excision of rectal procidentia with anastomosis by perineal approach	Anterior resection of rectum with anastomosis	Excision of rectal procidentia with anastomosis by perineal approach	Anterior resection of rectum and total mesorectal excision with colostomy	Closure of rectovaginal fistula by transanal approach	1
C0017601::pathology_of	pathology_of	For which condition is {subj} the pathology?	C0017601	Glaucoma	C0372995	Fistulization of sclera for glaucoma; thermocauterization with iridectomy	Cauterization of sclera with iridectomy	Fistulization of labyrinth for decompression	Fistulization of sclera for glaucoma; thermocauterization with iridectomy	Fistulization of sclera by trephination	2
C1515678::pathway_has_gene_element	pathway_has_gene_element	Which gene is an element in the pathway {subj}?	C1515678	p38 MAPK Signaling Pathway BioCarta	C3540622	PLA2G1B wt Allele	TBC1D2B wt Allele	PHB1 wt Allele	PLA2G1B wt Allele	ABTB2 wt Allele	2
C1517343::pathway_has_gene_element	pathway_has_gene_element	Which gene is an element in the pathway {subj}?	C1517343	G1/S Checkpoint Pathway	C4289048	GSK3B wt Allele	GCKR wt Allele	PICK1 wt Allele	GSK3B wt Allele	PDK3 wt Allele	2
C0920641::pathway_has_gene_element	pathway_has_gene_element	Which gene is an element in the pathway {subj}?	C0920641	Pyrimidine Metabolism Pathway	C1705746	TYMS wt Allele	RYK wt Allele	TYMS wt Allele	TIE1 wt Allele	TGM7 wt Allele	1
C5882689::phenotype_of	phenotype_of	Which genetic condition or organism has {subj} as a phenotype?	C5882689	NEURODEVELOPMENTAL DISORDER WITH LANGUAGE DELAY AND VARIABLE COGNITIVE ABNORMALITIES	C5882990	GABBR1, GLU368ASP	NUP98/ADD3 FUSION GENE	GABBR1, GLU368ASP	C11ORF95/RELA FUSION GENE	ARHGAP5 gene	1
C0268138::phenotype_of	phenotype_of	Which genetic condition or organism has {subj} as a phenotype?	C0268138	Xeroderma Pigmentosum, Complementation Group D	C1852054	ERCC2, ARG616TRP	CRTC1/MAML2 Fusion Gene	ERCC2, ARG616TRP	SMARCA2 gene	GRHL2 gene	1
C3540845::phenotype_of	phenotype_of	Which genetic condition or organism has {subj} as a phenotype?	C3540845	MICROPHTHALMIA, ISOLATED, WITH COLOBOMA 8	C3552356	STRA6, GLY304LYS	LY96 gene	MIRLET7F2 gene	STRA6, GLY304LYS	PIKFYVE gene	2
C1372092::physiologic_effect_of	physiologic_effect_of	For which drug or chemical is {subj} a physiologic effect?	C1372092	Increased Antibody Production	C3864830	L1 protein, human papillomavirus type 45 vaccine	oncogene protein E4, human papilloma virus type 1	E7 protein, human papillomavirus 11	Human papilloma virus 42 Ag	L1 protein, human papillomavirus type 45 vaccine	3
C2267052::physiologic_effect_of	physiologic_effect_of	For which drug or chemical is {subj} a physiologic effect?	C2267052	Increased Histamine Release	C2701502	mesquite pollen extract	Sarracenia extract	merbarone	Teucrium marum extract	mesquite pollen extract	3
C1372020::physiologic_effect_of	physiologic_effect_of	For which drug or chemical is {subj} a physiologic effect?	C1372020	Decreased Uterine Smooth Muscle Contraction or Tone	C1120952	norelgestromin	nomegestrol	megestrol compounding powder	norelgestromin	Ethinyl estradiol and norelgestromin only product	2
C0013746::population_at_risk_for	population_at_risk_for	Which condition is the population {subj} at risk for?	C0013746	Ejaculation	C0238015	Autonomic Dysreflexia	Autonomic neuropathy due to metabolic disease	Segmental Autonomic Dysfunction	Autonomic Dysreflexia	Reflex Sympathetic Dystrophy	2
C4540775::population_at_risk_for	population_at_risk_for	Which condition is the population {subj} at risk for?	C4540775	Significant bruising during birth	C0857007	Hyperbilirubinemia, Neonatal	Hyperglycinemia, Transient Neonatal	Hepatic failure, neonatal	Hyperbilirubinemia	Hyperbilirubinemia, Neonatal	3
C1283034::population_at_risk_for	population_at_risk_for	Which condition is the population {subj} at risk for?	C1283034	Maternal diabetes mellitus	C0028754	Obesity	Obesity associated disorder	Rickets	Other obesity	Obesity	3
C4236755::positively_regulated_by	positively_regulated_by	Which entity positively regulates {subj}?	C4236755	telomeric repeat-containing RNA transcription by RNA polymerase II	C3544836	positive regulation of telomeric RNA transcription from RNA pol II promoter	negative regulation of transcription elongation by RNA polymerase II	positive regulation of telomeric RNA transcription from RNA pol II promoter	transcriptional start site selection at RNA polymerase II promoter	nucleolar large rRNA transcription by RNA polymerase I	1
C1523816::positively_regulated_by	positively_regulated_by	Which entity positively regulates {subj}?	C1523816	macromolecule metabolic process	C2611899	positive regulation of macromolecule metabolic process	negative regulation of DNA catabolic process	negative regulation of cellular alcohol catabolic process	negative regulation of tetrapyrrole catabolic process	positive regulation of macromolecule metabolic process	3
C2262818::positively_regulated_by	positively_regulated_by	Which entity positively regulates {subj}?	C2262818	regulation of excitatory post-synaptic membrane potential	C3157706	positive regulation of excitatory postsynaptic potential	positive regulation of excitatory postsynaptic potential	negative regulation of postsynaptic membrane organization	regulation of protein catabolic process at presynapse, modulating synaptic transmission	negative regulation of presynaptic cytosolic calcium concentration	0
C1523066::positively_regulates	positively_regulates	Which entity is positively regulated by {subj}?	C1523066	positive regulation of calcium-independent cell-cell adhesion	C1154388	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	cell-cell adhesion involved in gastrulation	negative regulation of cell adhesion mediated by integrin	positive regulation of cell-cell adhesion	0
C1523130::positively_regulates	positively_regulates	Which entity is positively regulated by {subj}?	C1523130	positive regulation of DNA ligation	C1155649	DNA Ligation	DNA Ligation	bacterial-type DNA replication DNA ligation	DNA Groove Binding	DNA Intercalation	0
C4326564::positively_regulates	positively_regulates	Which entity is positively regulated by {subj}?	C4326564	positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process	C4326577	activated CD8-positive, alpha-beta T cell apoptotic process	CD4-positive, alpha-beta T cell differentiation involved in immune response	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	activated CD8-positive, alpha-beta T cell apoptotic process	CD8-positive, alpha-beta T cell differentiation involved in immune response	2
C5703713::precise_ingredient_of	precise_ingredient_of	Which medication or substance has {subj} as a precise ingredient?	C5703713	olipudase alfa-rpcp	C5703716	Xenpozyme	Proctozone-H	Xenpozyme	Enzyme variant	Rhamnulokinase	1
C0068980::precise_ingredient_of	precise_ingredient_of	Which medication or substance has {subj} as a precise ingredient?	C0068980	norethindrone acetate	C4081017	Fyavolv	Tibsovo	Evrysdi	Fyavolv	Rivotril	2
C0700468::precise_ingredient_of	precise_ingredient_of	Which medication or substance has {subj} as a precise ingredient?	C0700468	verapamil hydrochloride	C0010007	Cordilox	Cordilox	Koromex	Imovax Rabies	Folex PFS	0
C1305763::procedure_site_of	procedure_site_of	Which procedure targets the site {subj}?	C1305763	Skeletal and/or smooth muscle structure	C0185285	Deep biopsy of muscle	Biopsy of lower limb	open biopsy of peripheral nerve	Deep needle biopsy	Deep biopsy of muscle	3
C0040300::procedure_site_of	procedure_site_of	Which procedure targets the site {subj}?	C0040300	Body tissue	C0189809	Donor cardiectomy-pneumonectomy with preparation and maintenance of homograft	Backbench reconstruction of cadaver or living donor liver graft prior to allotransplantation; arterial anastomosis, each	Transplant preparation of hematopoietic progenitor cells; thawing of previously frozen harvest, with washing, per donor	Donor cardiectomy-pneumonectomy with preparation and maintenance of homograft	Backbench reconstruction of cadaver or living donor renal allograft prior to transplantation; venous anastomosis, each	2
C0037253::procedure_site_of	procedure_site_of	Which procedure targets the site {subj}?	C0037253	Skeletal system	C0441560	Internal fixation using intramedullary nail	Secondary open reduction of fracture of bone and intramedullary fixation	Internal fixation using intramedullary nail	reposition left radius with intramedullary internal fixation device	Fluoroscopy guided intramedullary nailing of fracture of bone	1
C0525006::process_includes_biological_process	process_includes_biological_process	Which biological process is included in the larger process {subj}?	C0525006	Myelopoiesis	C1513792	Myeloproliferation	Macrophage Activation	Myeloproliferation	Megasporogenesis	Erythrocyte Differentiation Pathway	1
C1511130::process_includes_biological_process	process_includes_biological_process	Which biological process is included in the larger process {subj}?	C1511130	Biochemical Processes	C3537131	Chelating Activity	Reduction Activity	Magnesium Ion Exchange Activity	Chelating Activity	Alkalinizing Activity	2
C0221145::process_includes_biological_process	process_includes_biological_process	Which biological process is included in the larger process {subj}?	C0221145	Thrombopoiesis	C1159950	Megakaryocyte Differentiation	positive regulation of myeloid leukocyte differentiation	negative regulation of megakaryocyte differentiation	megakaryocyte development	Megakaryocyte Differentiation	3
C1514762::process_involves_gene	process_involves_gene	Which gene is involved in the process {subj}?	C1514762	Receptor Signaling	C0812448	NKTR Gene	NKTR Gene	RICTOR gene	CRBN gene	RHCE gene	0
C1159772::process_involves_gene	process_involves_gene	Which gene is involved in the process {subj}?	C1159772	intracellular protein transport	C1333352	ERBIN gene	ERBIN gene	SNURF gene	MCOLN1 gene	LITAF gene	0
C1156210::process_involves_gene	process_involves_gene	Which gene is involved in the process {subj}?	C1156210	chromatin remodeling	C1706024	BRMS1 wt Allele	BRMS1 wt Allele	SMIM5 wt Allele	MACC1 wt Allele	PRRC1 wt Allele	0
C0037925::receives_input_from	receives_input_from	Which of the following provides input to {subj}?	C0037925	Spinal Cord	C2327337	Intermediate nucleus of solitary tract	Entire paracentral nucleus of thalamus	Entire central medial nucleus of thalamus	Intermediate nucleus of solitary tract	Entire lateral posterior nucleus of thalamus	2
C0175517::receives_input_from	receives_input_from	Which of the following provides input to {subj}?	C0175517	nucleus raphe pallidus	C0175446	medial parabrachial nucleus	nucleus of the lateral olfactory tract	Spinothalamic tract of medulla	medial parabrachial nucleus	Structure of medial reticulospinal tract	2
C0175289::receives_input_from	receives_input_from	Which of the following provides input to {subj}?	C0175289	principal part of the ventral posteromedial nucleus	C0017651	Globus Pallidus	Globus Pallidus	Auricular Vein	Entire subthalamus	Erector spinae in thorax	0
C0019655::related_to	related_to	Which of the following is related to {subj}?	C0019655	Histoplasmosis	C0026946	Mycoses	Mucormycosis	Mycoses	Mucosal yaws	Onychomycosis	1
C0278996::related_to	related_to	Which of the following is related to {subj}?	C0278996	Malignant Head and Neck Neoplasm	C0220636	Malignant neoplasm of salivary gland	Malignant neoplasm of salivary gland	Primary malignant neoplasm of minor salivary gland	Malignant neoplasm of submandibular gland	Primary malignant neoplasm of parotid gland	0
C0034606::related_to	related_to	Which of the following is related to {subj}?	C0034606	Radionuclide Imaging	C0011923	Diagnostic Imaging	Diagnostic aspiration	Diagnostic Imaging	Diagnostic radiography of soft tissues	Diagnostic radiography with measurements	1
C5785968::related_to_genetic_biomarker	related_to_genetic_biomarker	Which genetic biomarker is related to {subj}?	C5785968	t(11;14)(q13.2;q32)(MYEOV/IGH) Fusion Transcript [Identifier] in Blood or Tissue by FISH Nominal	C1417531	MYEOV gene	MYO1F gene	MYEOV gene	PYGM gene	SPANXE gene	1
C0546264::related_to_genetic_biomarker	related_to_genetic_biomarker	Which genetic biomarker is related to {subj}?	C0546264	Congenital Fiber Type Disproportion	C1412136	ACTA1 gene	CPA1 gene	ARG1 gene	ACAT1 gene	ACTA1 gene	3
C5786059::related_to_genetic_biomarker	related_to_genetic_biomarker	Which genetic biomarker is related to {subj}?	C5786059	Gamma-Enolase [Mass/Volume] in Aspirate	C1414404	ENO2 gene	ROBO2 gene	PIEZO2 gene	TDO2 gene	ENO2 gene	3
C2173827::same_as	same_as	Which of the following is the same as {subj}?	C2173827	ultrasound of left popliteal fossa	C4511171	Ultrasonography of left popliteal fossa	Ultrasonography of toe of left foot	B-mode ultrasound of popliteal vein	Ultrasonography of left foot	Ultrasonography of left popliteal fossa	3
C3693486::same_as	same_as	Which of the following is the same as {subj}?	C3693486	squamous cell carcinoma of auricle of external ear	C1827143	Squamous cell carcinoma of auricle of ear	Squamous cell carcinoma of auricle of ear	Squamous cell carcinoma of bridge of nose	Primary squamous cell carcinoma of right ear	Squamous cell carcinoma of skin of left ear and external auricular canal	0
C5389450::same_as	same_as	Which of the following is the same as {subj}?	C5389450	conversion from previous hybrid total prosthetic hip replacement	C3165057	Conversion from hybrid total prosthetic hip replacement	Conversion to cemented total prosthetic replacement of joint	Conversion from hybrid total prosthetic hip replacement	Conversion from hybrid total shoulder replacement	Conversion to hybrid total replacement ankle joint	1
C1305854::segmental_supply_of	segmental_supply_of	Which anatomical structure has {subj} as its segmental supply?	C1305854	C8 innervation	C0224262	Flexor pollicis longus	Right abductor pollicis brevis	Entire extensor pollicis longus muscle	Entire flexor pollicis longus muscle tendon	Flexor pollicis longus	3
C1305856::segmental_supply_of	segmental_supply_of	Which anatomical structure has {subj} as its segmental supply?	C1305856	C1 innervation	C0449164	First anterior cervical intertransversarius	Cervical intertransversarius	First anterior cervical intertransversarius	Structure of posterior cervical intertransversarius muscle	Entire C1-C2 intertransversarius cervicis anterior	1
C1305860::segmental_supply_of	segmental_supply_of	Which anatomical structure has {subj} as its segmental supply?	C1305860	C6 innervation	C0224248	Articularis cubiti	Articularis cubiti	Nerve to left articularis cubiti	Incisivus labii superioris	Entire articularis genu muscle	0
C0175222::sends_output_to	sends_output_to	Which of the following receives output from {subj}?	C0175222	basolateral nucleus of the amygdala	C0034169	Structure of putamen	Structure of putamen	Structure of surface thalamic vein	Structure of cuneiform nucleus of midbrain	Structure of cingulum	0
C0162783::sends_output_to	sends_output_to	Which of the following receives output from {subj}?	C0162783	Prefrontal Cortex	C0228249	Parahippocampal Gyrus	Parahippocampal Gyrus	Parietal gyrus structure	Paraterminal gyrus	Entire frontal lobe gyrus	0
C0086596::sends_output_to	sends_output_to	Which of the following receives output from {subj}?	C0086596	Medial geniculate body	C2328538	Brodmann area 41	Brodmann area 41	Entire Brodmann area 9, granular frontal	Entire Brodmann area 10, frontopolar	Entire Brodmann area 1, intermediate postcentral	0
C1551303::specialty_of	specialty_of	For which medical field or procedure is {subj} a specialty?	C1551303	Independent Physiological Laboratory	C0202758	Computed tomography of soft tissues of neck without contrast	Computed tomography of abdomen and pelvis with intravenous contrast	Computed tomography of adrenals	Computed tomography of soft tissues of neck without contrast	Computed tomography of small intestine with contrast	2
C1551301::specialty_of	specialty_of	For which medical field or procedure is {subj} a specialty?	C1551301	Clinical Medical Laboratory	C3248183	MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants	MSH6 (mutS homolog 6) (eg, hereditary colon cancer, Lynch syndrome) mRNA sequence analysis (List separately in addition to code for primary procedure)	APC (APC regulator of WNT signaling pathway) (eg, familial adenomatosis polyposis [FAP]) mRNA sequence analysis (List separately in addition to code for primary procedure)	EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) (eg, myelodysplastic syndrome, myeloproliferative neoplasms) gene analysis, full gene sequence	MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants	3
C0031322::specialty_of	specialty_of	For which medical field or procedure is {subj} a specialty?	C0031322	Pharmacy facility	C4051835	Influenza virus vaccine, quadrivalent, live (LAIV4), for intranasal use	Hepatitis A vaccine (HepA), pediatric/adolescent dosage-2 dose schedule, for intramuscular use	Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, subunit, preservative and antibiotic free, 0.5 mL dosage, for intramuscular use	Influenza virus vaccine, quadrivalent, live (LAIV4), for intranasal use	Human Papillomavirus vaccine, types 16, 18, bivalent (2vHPV), 3 dose schedule, for intramuscular use	2
C0026860::specimen_source_topography_of	specimen_source_topography_of	For which laboratory test is {subj} the specimen source topography?	C0026860	Musculoskeletal System	C0586570	Excised tendon specimen	Entire subcutaneous tissue of lower extremity	Excised tendon specimen	Retinaculum of flexor muscles	Structure of fascia of upper extremity	1
C0040300::specimen_source_topography_of	specimen_source_topography_of	For which laboratory test is {subj} the specimen source topography?	C0040300	Body tissue	C1292587	Specimen from large intestine obtained by incisional biopsy	Small intestine mucous membrane	Specimen from large intestine obtained by incisional biopsy	Entire appendiceal mucous membrane	Structure of subserous tissue of parietal peritoneum	1
C0042232::specimen_source_topography_of	specimen_source_topography_of	For which laboratory test is {subj} the specimen source topography?	C0042232	Vagina	C1301220	Specimen from vagina obtained by partial vaginectomy	Structure of uterine tubal epithelium	Entire subcutaneous tissue of lower margin of nasal septum	Specimen from vagina obtained by partial vaginectomy	Entire subcutaneous tissue of vulva	2
C0032385::structural_class_of	structural_class_of	For which entity is {subj} the structural class?	C0032385	Pollen	C2723639	dogfennel pollen extract	Adansonia digitata fruit extract	Yucca schidigera extract	dog hair extract / English plantain pollen extract	dogfennel pollen extract	3
C0282564::structural_class_of	structural_class_of	For which entity is {subj} the structural class?	C0282564	Anthracyclines	C0020789	idarubicin	amifostine	idarubicin	amifampridine	miocamycin	1

C0014869::may_be_treated_by

may_be_treated_by

Which of the following may treat {subj}?

C0014869

Peptic Esophagitis

C0052993

basic aluminum carbonate gel

calcium phosphate / picolinic acid

lithium carbonate / sodium chloride

basic aluminum carbonate gel

ammonium phosphate

2

C0011777::may_prevent

may_prevent

Which of the following may be prevented by {subj}?

C0011777

dexamethasone

C0004096

Asthma

Other Asthma

Childhood asthma

Asthma-like condition

Asthma

3

C0060231::may_prevent

may_prevent

Which of the following may be prevented by {subj}?

C0060231

ferric citrate

C0162316

Iron deficiency anemia

Anemia due to protein deficiency

Iron deficiency anemia secondary to chronic blood loss

Other deficiency anemias

0

C0991853::may_prevent

may_prevent

Which of the following may be prevented by {subj}?

C0991853

nicotinamide hydriodide

C1956346

Coronary Artery Disease

Renal Artery Disease

Carotid Artery Diseases

Coronary bypass stenosis

0

C0123053::may_treat

may_treat

Which of the following may be treated by {subj}?

C0123053

ibutilide fumarate

C0003811

Cardiac Arrhythmia

Drug induced arrhythmia

Cardiac Arrhythmia

Arrhythmia during surgery

Arrhythmia-Induced Cardiomyopathy

1

C0022489::may_treat

may_treat

Which of the following may be treated by {subj}?

C0022489

kanamycin A

C0085394

Serratia Infections

Sepsis caused by Serratia

Hantavirus Infections

Cecal Infection

Serratia Infections

3

C0812398::may_treat

may_treat

Which of the following may be treated by {subj}?

C0812398

hetacillin potassium

C0022729

Klebsiella Infections

Klebsiella urinary tract infection

Corynebacterium Infections

Bacterial infection caused by Klebsiella pneumoniae

0

C2757006::mechanism_of_action_of

mechanism_of_action_of

For which drug or chemical is {subj} the mechanism of action?

C2757006

Immunologic Factor Interactions [MoA]

C0556243

propylparaben sodium

icometasone enbutate

propylparaben sodium

fenipentol

butaperazine maleate

1

C1373138::mechanism_of_action_of

mechanism_of_action_of

For which drug or chemical is {subj} the mechanism of action?

C1373138

Transpeptidase Inhibitors

C0007735

cephalothin

cloxazolam

cethromycin

cefonicid sodium injection

0

C2757009::mechanism_of_action_of

mechanism_of_action_of

For which drug or chemical is {subj} the mechanism of action?

C2757009

Nucleic Acid Synthesis Inhibitors [MoA]

C0771588

quinine ascorbate

ascorbic acid buffered

quinine ascorbate

ascorbic acid / dequalinium

ascorbic acid / bee pollen

1

C5205177::molecular_abnormality_involves_gene

molecular_abnormality_involves_gene

Which gene is involved in the molecular abnormality {subj}?

C5205177

ETV Gene Rearrangement

C0812200

ETS Family Gene

FES gene

ADAM Family Gene

XAGE1 Family Gene

0

C1709998::molecular_abnormality_involves_gene

molecular_abnormality_involves_gene

Which gene is involved in the molecular abnormality {subj}?

C1709998

SS18-SSX Fusion Protein Expression

C1420439

SS18 gene

ID2 gene

SS18 gene

ID4 gene

AASS gene

1

C5708027::molecular_abnormality_involves_gene

molecular_abnormality_involves_gene

Which gene is involved in the molecular abnormality {subj}?

C5708027

EZH2 NM_004456.5:c.1936T>G

C1333368

EZH2 gene

HERC2 gene

EGR2 gene

EZH2 gene

ALKBH7 gene

2

C1820119::negatively_regulated_by

negatively_regulated_by

Which entity negatively regulates {subj}?

C1820119

Mitophagy

C3547217

negative regulation of mitophagy

positive regulation of lysosome organization

negative regulation of mitophagy

positive regulation of vacuole fusion, non-autophagic

positive regulation of phagocytosis

1

C2611051::negatively_regulated_by

negatively_regulated_by

Which entity negatively regulates {subj}?

C2611051

brown fat cell proliferation

C2611060

negative regulation of brown fat cell proliferation

positive regulation of type B pancreatic cell development

positive regulation of lens fiber cell differentiation

negative regulation of brown fat cell proliferation

positive regulation of B cell proliferation

2

C0752319::negatively_regulated_by

negatively_regulated_by

Which entity negatively regulates {subj}?

C0752319

MAP Kinase Cascade

C2248527

negative regulation of MAPK cascade

canonical Wnt signaling pathway involved in negative regulation of apoptotic process

positive regulation of protein kinase B signaling

positive regulation of apoptotic signaling pathway

negative regulation of MAPK cascade

3

C4327435::negatively_regulates

negatively_regulates

Which entity is negatively regulated by {subj}?

C4327435

negative regulation of cellular response to manganese ion

C2754488

cellular response to manganese ion

cellular response to insulin stimulus

positive regulation of cellular response to manganese ion

cellular response to manganese ion

cellular response to cytokinin stimulus

2

C1523067::negatively_regulates

negatively_regulates

Which entity is negatively regulated by {subj}?

C1523067

negative regulation of calcium-independent cell-cell adhesion

C1154388

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

negative regulation of leukocyte cell-cell adhesion

negative regulation of homophilic cell adhesion

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

cell-matrix adhesion involved in tangential migration using cell-cell interactions

2

C3157499::negatively_regulates

negatively_regulates

Which entity is negatively regulated by {subj}?

C3157499

negative regulation of Rho-dependent protein serine/threonine kinase activity

C3156573

Rho-dependent protein serine/threonine kinase activity

negative regulation of protein tyrosine phosphatase activity

SRC Tyrosine Kinase Activation Pathway

positive regulation of peptidyl-tyrosine autophosphorylation

Rho-dependent protein serine/threonine kinase activity

3

C2328236::nerve_supply_of

nerve_supply_of

Which anatomical structure has {subj} as its nerve supply?

C2328236

T3 branch to left semispinalis thoracis

C0816124

Left semispinalis thoracis

Set of right semispinalis muscles

Left semispinalis thoracis

Left second interspinalis lumborum

T7 branch to left semispinalis thoracis

1

C2329296::nerve_supply_of

nerve_supply_of

Which anatomical structure has {subj} as its nerve supply?

C2329296

Nerve to depressor anguli oris

C0224113

Depressor anguli oris muscle structure

Entire adductor brevis muscle

Entire second levator costae brevis

Depressor anguli oris muscle structure

Entire levator labii superioris muscle

2

C2333910::nerve_supply_of

nerve_supply_of

Which anatomical structure has {subj} as its nerve supply?

C2333910

Nerve to right rhomboid major

C0507195

Right rhomboid major

Right coracoid process

Right rhomboid major

Entire rhomboid major muscle

Right superciliary arch

1

C0038967::occurs_after

occurs_after

Which of the following occurs after {subj}?

C0038967

Suture granuloma

C0184661

Interventional procedure

Surgical manipulation procedure

Interventional procedure

Physical Treatment Methods

Interventional debulking surgery

1

C0264767::occurs_after

occurs_after

Which of the following occurs after {subj}?

C0264767

Rheumatic mitral stenosis with insufficiency

C0554628

Group A Streptococcal Infections

Streptococcal sepsis

Staphylococcal Skin Infections

group G Streptococcal infection

Group A Streptococcal Infections

3

C2316651::occurs_after

occurs_after

Which of the following occurs after {subj}?

C2316651

Infection of total ankle joint prosthesis

C0188664

Total ankle replacement

Primary hybrid total elbow replacement

Hip joint reconstruction

Total ankle replacement

Reconstruction of ankle joint

2

C3662483::occurs_before

occurs_before

Which of the following occurs before {subj}?

C3662483

Allergic sensitization

C0571821

Multiple electrolyte infusion allergy

Allergy to lithium compound

Topical adhesive allergy

Elastoplast allergy

Multiple electrolyte infusion allergy

3

C5686631::occurs_before

occurs_before

Which of the following occurs before {subj}?

C5686631

Reconstruction using flap

C5768624

Partial myocutaneous flap necrosis

Skin necrosis due to heparin induced thrombocytopenia

Intraoperative open wound of scalp associated with Mayfield head clamp

Avascular necrosis of metatarsal bone

Partial myocutaneous flap necrosis

3

C0184661::occurs_before

occurs_before

Which of the following occurs before {subj}?

C0184661

Interventional procedure

C0274311

Complication of surgical procedure

Complication of acute stroke

Complication of breast implant surgery

Complication of surgical procedure

Surgical Complication

2

C1325422::occurs_in

occurs_in

In which of the following does {subj} occur?

C1325422

extracellular matrix structural constituent

C0015350

Extracellular Matrix

Epidermal basement zone

Extracellular Matrix

Basal Lamina Collagen

Entire connective tissue

1

C1152928::occurs_in

occurs_in

In which of the following does {subj} occur?

C1152928

structural constituent of myelin sheath

C0026973

Myelin Sheath

Electron-Dense Plasma Membrane Layer

Myelin Sheath

Outer Leaflet of the Lipid Bilayer

Meiotic Spindle Apparatus

1

C4328744::occurs_in

occurs_in

In which of the following does {subj} occur?

C4328744

somato-dendritic dopamine secretion

C3893311

somatodendritic compartment

extrinsic component of presynaptic active zone membrane

myelin sheath adaxonal region

axonemal central bridge

somatodendritic compartment

3

C0086418::organism_has_gene

organism_has_gene

Which gene is found in the organism {subj}?

C0086418

Homo sapiens

C1412338

ALDH1B1 gene

ALDH5A1, EX7DEL

ALDH1B1 gene

PCAT1 gene

BCKDHB gene

1

C0458621::part_of

part_of

Which of the following contains {subj} as a part?

C0458621

Entire sinus epididymidis

C0014533

Epididymis

Ligament of epididymis

Epididymis

Adventitia of epididymis

Lobule of right epididymis

1

C0924087::part_of

part_of

Which of the following contains {subj} as a part?

C0924087

Inferior fibular retinaculum

C0929803

Investing fascia of right ankle

Fascia of right shoulder

Superficial fascia of right leg

Investing fascia of pelvic girdle

Investing fascia of right ankle

3

C0448625::part_of

part_of

Which of the following contains {subj} as a part?

C0448625

Tendon of anterior crural muscle

C1269079

Entire lower limb

Entire nervous of limb

Entire median nerve

Entire external oblique

Entire lower limb

3

C0302592::pathogenesis_of_disease_involves_gene

pathogenesis_of_disease_involves_gene

Which gene is involved in the pathogenesis of the disease {subj}?

C0302592

Cervix carcinoma

C0079419

TP53 gene

TAF6 gene

TPM3 gene

TRAT1 gene

0

C4054911::pathogenesis_of_disease_involves_gene

pathogenesis_of_disease_involves_gene

Which gene is involved in the pathogenesis of the disease {subj}?

C4054911

Fusion-Positive Rhabdomyosarcoma

C1847791

PAX3/FOXO1 Fusion Gene

SS18L1/SSX1 Fusion Gene

MLL/ARHGAP26 Fusion Gene

NUP98/PRRX1 Fusion Gene

PAX3/FOXO1 Fusion Gene

3

C0950121::pathogenesis_of_disease_involves_gene

pathogenesis_of_disease_involves_gene

Which gene is involved in the pathogenesis of the disease {subj}?

C0950121

Denys-Drash Syndrome

C0694898

WT1 gene

TAL1 gene

WFS1 gene

TET1 gene

WT1 gene

3

C2711370::pathological_process_of

pathological_process_of

For which condition is {subj} the pathological process?

C2711370

Parasitic process

C0276893

Infection by Nosema bombycis

Sporothrix schenckii Infection

Capnocytophaga canimorsus sepsis

Infection due to Penicillium mycetogenum

Infection by Nosema bombycis

3

C0009450::pathological_process_of

pathological_process_of

For which condition is {subj} the pathological process?

C0009450

Communicable Diseases

C0276854

Infection by Babesia canis

babesiosis other due to Babesia venatorum

Infection by Babesia canis

Infection by Histoplasma capsulatum, other

Infection due to Penicillium mycetogenum

1

C0745283::pathological_process_of

pathological_process_of

For which condition is {subj} the pathological process?

C0745283

INFECTIOUS PROCESS

C0042636

Vibrio Infections

Cecal Infection

Balamuthia Infection

Parainfluenza Virus Infections

Vibrio Infections

3

C0027651::pathology_of

pathology_of

For which condition is {subj} the pathology?

C0027651

Neoplasms

C0371474

Thoracoscopy, surgical; with excision of pericardial cyst, tumor, or mass

Creation of pericardial window or partial resection for drainage

Pericardiotomy and drainage of effusion

Mediastinotomy with exploration, drainage, removal of foreign body, or biopsy; cervical approach

0

C0033377::pathology_of

pathology_of

For which condition is {subj} the pathology?

C0033377

Ptosis

C0193094

Excision of rectal procidentia with anastomosis by perineal approach

Anterior resection of rectum with anastomosis

Excision of rectal procidentia with anastomosis by perineal approach

Anterior resection of rectum and total mesorectal excision with colostomy

Closure of rectovaginal fistula by transanal approach

1

C0017601::pathology_of

pathology_of

For which condition is {subj} the pathology?

C0017601

Glaucoma

C0372995

Fistulization of sclera for glaucoma; thermocauterization with iridectomy

Cauterization of sclera with iridectomy

Fistulization of labyrinth for decompression

Fistulization of sclera for glaucoma; thermocauterization with iridectomy

Fistulization of sclera by trephination

2

C1515678::pathway_has_gene_element

pathway_has_gene_element

Which gene is an element in the pathway {subj}?

C1515678

p38 MAPK Signaling Pathway BioCarta

C3540622

PLA2G1B wt Allele

TBC1D2B wt Allele

PHB1 wt Allele

PLA2G1B wt Allele

ABTB2 wt Allele

2

C1517343::pathway_has_gene_element

pathway_has_gene_element

Which gene is an element in the pathway {subj}?

C1517343

G1/S Checkpoint Pathway

C4289048

GSK3B wt Allele

GCKR wt Allele

PICK1 wt Allele

GSK3B wt Allele

PDK3 wt Allele

2

C0920641::pathway_has_gene_element

pathway_has_gene_element

Which gene is an element in the pathway {subj}?

C0920641

Pyrimidine Metabolism Pathway

C1705746

TYMS wt Allele

RYK wt Allele

TYMS wt Allele

TIE1 wt Allele

TGM7 wt Allele

1

C5882689::phenotype_of

phenotype_of

Which genetic condition or organism has {subj} as a phenotype?

C5882689

NEURODEVELOPMENTAL DISORDER WITH LANGUAGE DELAY AND VARIABLE COGNITIVE ABNORMALITIES

C5882990

GABBR1, GLU368ASP

NUP98/ADD3 FUSION GENE

GABBR1, GLU368ASP

C11ORF95/RELA FUSION GENE

ARHGAP5 gene

1

C0268138::phenotype_of

phenotype_of

Which genetic condition or organism has {subj} as a phenotype?

C0268138

Xeroderma Pigmentosum, Complementation Group D

C1852054

ERCC2, ARG616TRP

CRTC1/MAML2 Fusion Gene

ERCC2, ARG616TRP

SMARCA2 gene

GRHL2 gene

1

C3540845::phenotype_of

phenotype_of

Which genetic condition or organism has {subj} as a phenotype?

C3540845

MICROPHTHALMIA, ISOLATED, WITH COLOBOMA 8

C3552356

STRA6, GLY304LYS

LY96 gene

MIRLET7F2 gene

STRA6, GLY304LYS

PIKFYVE gene

2

C1372092::physiologic_effect_of

physiologic_effect_of

For which drug or chemical is {subj} a physiologic effect?

C1372092

Increased Antibody Production

C3864830

L1 protein, human papillomavirus type 45 vaccine

oncogene protein E4, human papilloma virus type 1

E7 protein, human papillomavirus 11

Human papilloma virus 42 Ag

L1 protein, human papillomavirus type 45 vaccine

3

C2267052::physiologic_effect_of

physiologic_effect_of

For which drug or chemical is {subj} a physiologic effect?

C2267052

Increased Histamine Release

C2701502

mesquite pollen extract

Sarracenia extract

merbarone

Teucrium marum extract

mesquite pollen extract

3

C1372020::physiologic_effect_of

physiologic_effect_of

For which drug or chemical is {subj} a physiologic effect?

C1372020

Decreased Uterine Smooth Muscle Contraction or Tone

C1120952

norelgestromin

nomegestrol

megestrol compounding powder

norelgestromin

Ethinyl estradiol and norelgestromin only product

2

C0013746::population_at_risk_for

population_at_risk_for

Which condition is the population {subj} at risk for?

C0013746

Ejaculation

C0238015

Autonomic Dysreflexia

Autonomic neuropathy due to metabolic disease

Segmental Autonomic Dysfunction

Autonomic Dysreflexia

Reflex Sympathetic Dystrophy

2

C4540775::population_at_risk_for

population_at_risk_for

Which condition is the population {subj} at risk for?

C4540775

Significant bruising during birth

C0857007

Hyperbilirubinemia, Neonatal

Hyperglycinemia, Transient Neonatal

Hepatic failure, neonatal

Hyperbilirubinemia

Hyperbilirubinemia, Neonatal

3

C1283034::population_at_risk_for

population_at_risk_for

Which condition is the population {subj} at risk for?

C1283034

Maternal diabetes mellitus

C0028754

Obesity

Obesity associated disorder

Rickets

Other obesity

Obesity

3

C4236755::positively_regulated_by

positively_regulated_by

Which entity positively regulates {subj}?

C4236755

telomeric repeat-containing RNA transcription by RNA polymerase II

C3544836

positive regulation of telomeric RNA transcription from RNA pol II promoter

negative regulation of transcription elongation by RNA polymerase II

positive regulation of telomeric RNA transcription from RNA pol II promoter

transcriptional start site selection at RNA polymerase II promoter

nucleolar large rRNA transcription by RNA polymerase I

1

C1523816::positively_regulated_by

positively_regulated_by

Which entity positively regulates {subj}?

C1523816

macromolecule metabolic process

C2611899

positive regulation of macromolecule metabolic process

negative regulation of DNA catabolic process

negative regulation of cellular alcohol catabolic process

negative regulation of tetrapyrrole catabolic process

positive regulation of macromolecule metabolic process

3

C2262818::positively_regulated_by

positively_regulated_by

Which entity positively regulates {subj}?

C2262818

regulation of excitatory post-synaptic membrane potential

C3157706

positive regulation of excitatory postsynaptic potential

negative regulation of postsynaptic membrane organization

regulation of protein catabolic process at presynapse, modulating synaptic transmission

negative regulation of presynaptic cytosolic calcium concentration

0

C1523066::positively_regulates

positively_regulates

Which entity is positively regulated by {subj}?

C1523066

positive regulation of calcium-independent cell-cell adhesion

C1154388

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

cell-cell adhesion involved in gastrulation

negative regulation of cell adhesion mediated by integrin

positive regulation of cell-cell adhesion

0

C1523130::positively_regulates

positively_regulates

Which entity is positively regulated by {subj}?

C1523130

positive regulation of DNA ligation

C1155649

DNA Ligation

bacterial-type DNA replication DNA ligation

DNA Groove Binding

DNA Intercalation

0

C4326564::positively_regulates

positively_regulates

Which entity is positively regulated by {subj}?

C4326564

positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process

C4326577

activated CD8-positive, alpha-beta T cell apoptotic process

CD4-positive, alpha-beta T cell differentiation involved in immune response

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

activated CD8-positive, alpha-beta T cell apoptotic process

CD8-positive, alpha-beta T cell differentiation involved in immune response

2

C5703713::precise_ingredient_of

precise_ingredient_of

Which medication or substance has {subj} as a precise ingredient?

C5703713

olipudase alfa-rpcp

C5703716

Xenpozyme

Proctozone-H

Xenpozyme

Enzyme variant

Rhamnulokinase

1

C0068980::precise_ingredient_of

precise_ingredient_of

Which medication or substance has {subj} as a precise ingredient?

C0068980

norethindrone acetate

C4081017

Fyavolv

Tibsovo

Evrysdi

Fyavolv

Rivotril

2

C0700468::precise_ingredient_of

precise_ingredient_of

Which medication or substance has {subj} as a precise ingredient?

C0700468

verapamil hydrochloride

C0010007

Cordilox

Koromex

Imovax Rabies

Folex PFS

0

C1305763::procedure_site_of

procedure_site_of

Which procedure targets the site {subj}?

C1305763

Skeletal and/or smooth muscle structure

C0185285

Deep biopsy of muscle

Biopsy of lower limb

open biopsy of peripheral nerve

Deep needle biopsy

Deep biopsy of muscle

3

C0040300::procedure_site_of

procedure_site_of

Which procedure targets the site {subj}?

C0040300

Body tissue

C0189809

Donor cardiectomy-pneumonectomy with preparation and maintenance of homograft

Backbench reconstruction of cadaver or living donor liver graft prior to allotransplantation; arterial anastomosis, each

Transplant preparation of hematopoietic progenitor cells; thawing of previously frozen harvest, with washing, per donor

Donor cardiectomy-pneumonectomy with preparation and maintenance of homograft

Backbench reconstruction of cadaver or living donor renal allograft prior to transplantation; venous anastomosis, each

2

C0037253::procedure_site_of

procedure_site_of

Which procedure targets the site {subj}?

C0037253

Skeletal system

C0441560

Internal fixation using intramedullary nail

Secondary open reduction of fracture of bone and intramedullary fixation

Internal fixation using intramedullary nail

reposition left radius with intramedullary internal fixation device

Fluoroscopy guided intramedullary nailing of fracture of bone

1

C0525006::process_includes_biological_process

process_includes_biological_process

Which biological process is included in the larger process {subj}?

C0525006

Myelopoiesis

C1513792

Myeloproliferation

Macrophage Activation

Myeloproliferation

Megasporogenesis

Erythrocyte Differentiation Pathway

1

C1511130::process_includes_biological_process

process_includes_biological_process

Which biological process is included in the larger process {subj}?

C1511130

Biochemical Processes

C3537131

Chelating Activity

Reduction Activity

Magnesium Ion Exchange Activity

Chelating Activity

Alkalinizing Activity

2

C0221145::process_includes_biological_process

process_includes_biological_process

Which biological process is included in the larger process {subj}?

C0221145

Thrombopoiesis

C1159950

Megakaryocyte Differentiation

positive regulation of myeloid leukocyte differentiation

negative regulation of megakaryocyte differentiation

megakaryocyte development

Megakaryocyte Differentiation

3

C1514762::process_involves_gene

process_involves_gene

Which gene is involved in the process {subj}?

C1514762

Receptor Signaling

C0812448

NKTR Gene

RICTOR gene

CRBN gene

RHCE gene

0

C1159772::process_involves_gene

process_involves_gene

Which gene is involved in the process {subj}?

C1159772

intracellular protein transport

C1333352

ERBIN gene

SNURF gene

MCOLN1 gene

LITAF gene

0

C1156210::process_involves_gene

process_involves_gene

Which gene is involved in the process {subj}?

C1156210

chromatin remodeling

C1706024

BRMS1 wt Allele

SMIM5 wt Allele

MACC1 wt Allele

PRRC1 wt Allele

0

C0037925::receives_input_from

receives_input_from

Which of the following provides input to {subj}?

C0037925

Spinal Cord

C2327337

Intermediate nucleus of solitary tract

Entire paracentral nucleus of thalamus

Entire central medial nucleus of thalamus

Intermediate nucleus of solitary tract

Entire lateral posterior nucleus of thalamus

2

C0175517::receives_input_from

receives_input_from

Which of the following provides input to {subj}?

C0175517

nucleus raphe pallidus

C0175446

medial parabrachial nucleus

nucleus of the lateral olfactory tract

Spinothalamic tract of medulla

medial parabrachial nucleus

Structure of medial reticulospinal tract

2

C0175289::receives_input_from

receives_input_from

Which of the following provides input to {subj}?

C0175289

principal part of the ventral posteromedial nucleus

C0017651

Globus Pallidus

Auricular Vein

Entire subthalamus

Erector spinae in thorax

0

C0019655::related_to

related_to

Which of the following is related to {subj}?

C0019655

Histoplasmosis

C0026946

Mycoses

Mucormycosis

Mycoses

Mucosal yaws

Onychomycosis

1

C0278996::related_to

related_to

Which of the following is related to {subj}?

C0278996

Malignant Head and Neck Neoplasm

C0220636

Malignant neoplasm of salivary gland

Primary malignant neoplasm of minor salivary gland

Malignant neoplasm of submandibular gland

Primary malignant neoplasm of parotid gland

0

C0034606::related_to

related_to

Which of the following is related to {subj}?

C0034606

Radionuclide Imaging

C0011923

Diagnostic Imaging

Diagnostic aspiration

Diagnostic Imaging

Diagnostic radiography of soft tissues

Diagnostic radiography with measurements

1

C5785968::related_to_genetic_biomarker

related_to_genetic_biomarker

Which genetic biomarker is related to {subj}?

C5785968

t(11;14)(q13.2;q32)(MYEOV/IGH) Fusion Transcript [Identifier] in Blood or Tissue by FISH Nominal

C1417531

MYEOV gene

MYO1F gene

MYEOV gene

PYGM gene

SPANXE gene

1

C0546264::related_to_genetic_biomarker

related_to_genetic_biomarker

Which genetic biomarker is related to {subj}?

C0546264

Congenital Fiber Type Disproportion

C1412136

ACTA1 gene

CPA1 gene

ARG1 gene

ACAT1 gene

ACTA1 gene

3

C5786059::related_to_genetic_biomarker

related_to_genetic_biomarker

Which genetic biomarker is related to {subj}?

C5786059

Gamma-Enolase [Mass/Volume] in Aspirate

C1414404

ENO2 gene

ROBO2 gene

PIEZO2 gene

TDO2 gene

ENO2 gene

3

C2173827::same_as

same_as

Which of the following is the same as {subj}?

C2173827

ultrasound of left popliteal fossa

C4511171

Ultrasonography of left popliteal fossa

Ultrasonography of toe of left foot

B-mode ultrasound of popliteal vein

Ultrasonography of left foot

Ultrasonography of left popliteal fossa

3

C3693486::same_as

same_as

Which of the following is the same as {subj}?

C3693486

squamous cell carcinoma of auricle of external ear

C1827143

Squamous cell carcinoma of auricle of ear

Squamous cell carcinoma of bridge of nose

Primary squamous cell carcinoma of right ear

Squamous cell carcinoma of skin of left ear and external auricular canal

0

C5389450::same_as

same_as

Which of the following is the same as {subj}?

C5389450

conversion from previous hybrid total prosthetic hip replacement

C3165057

Conversion from hybrid total prosthetic hip replacement

Conversion to cemented total prosthetic replacement of joint

Conversion from hybrid total prosthetic hip replacement

Conversion from hybrid total shoulder replacement

Conversion to hybrid total replacement ankle joint

1

C1305854::segmental_supply_of

segmental_supply_of

Which anatomical structure has {subj} as its segmental supply?

C1305854

C8 innervation

C0224262

Flexor pollicis longus

Right abductor pollicis brevis

Entire extensor pollicis longus muscle

Entire flexor pollicis longus muscle tendon

Flexor pollicis longus

3

C1305856::segmental_supply_of

segmental_supply_of

Which anatomical structure has {subj} as its segmental supply?

C1305856

C1 innervation

C0449164

First anterior cervical intertransversarius

Cervical intertransversarius

First anterior cervical intertransversarius

Structure of posterior cervical intertransversarius muscle

Entire C1-C2 intertransversarius cervicis anterior

1

C1305860::segmental_supply_of

segmental_supply_of

Which anatomical structure has {subj} as its segmental supply?

C1305860

C6 innervation

C0224248

Articularis cubiti

Nerve to left articularis cubiti

Incisivus labii superioris

Entire articularis genu muscle

0

C0175222::sends_output_to

sends_output_to

Which of the following receives output from {subj}?

C0175222

basolateral nucleus of the amygdala

C0034169

Structure of putamen

Structure of surface thalamic vein

Structure of cuneiform nucleus of midbrain

Structure of cingulum

0

C0162783::sends_output_to

sends_output_to

Which of the following receives output from {subj}?

C0162783

Prefrontal Cortex

C0228249

Parahippocampal Gyrus

Parietal gyrus structure

Paraterminal gyrus

Entire frontal lobe gyrus

0

C0086596::sends_output_to

sends_output_to

Which of the following receives output from {subj}?

C0086596

Medial geniculate body

C2328538

Brodmann area 41

Entire Brodmann area 9, granular frontal

Entire Brodmann area 10, frontopolar

Entire Brodmann area 1, intermediate postcentral

0

C1551303::specialty_of

specialty_of

For which medical field or procedure is {subj} a specialty?

C1551303

Independent Physiological Laboratory

C0202758

Computed tomography of soft tissues of neck without contrast

Computed tomography of abdomen and pelvis with intravenous contrast

Computed tomography of adrenals

Computed tomography of soft tissues of neck without contrast

Computed tomography of small intestine with contrast

2

C1551301::specialty_of

specialty_of

For which medical field or procedure is {subj} a specialty?

C1551301

Clinical Medical Laboratory

C3248183

MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants

MSH6 (mutS homolog 6) (eg, hereditary colon cancer, Lynch syndrome) mRNA sequence analysis (List separately in addition to code for primary procedure)

APC (APC regulator of WNT signaling pathway) (eg, familial adenomatosis polyposis [FAP]) mRNA sequence analysis (List separately in addition to code for primary procedure)

EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) (eg, myelodysplastic syndrome, myeloproliferative neoplasms) gene analysis, full gene sequence

MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants

3

C0031322::specialty_of

specialty_of

For which medical field or procedure is {subj} a specialty?

C0031322

Pharmacy facility

C4051835

Influenza virus vaccine, quadrivalent, live (LAIV4), for intranasal use

Hepatitis A vaccine (HepA), pediatric/adolescent dosage-2 dose schedule, for intramuscular use

Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, subunit, preservative and antibiotic free, 0.5 mL dosage, for intramuscular use

Influenza virus vaccine, quadrivalent, live (LAIV4), for intranasal use

Human Papillomavirus vaccine, types 16, 18, bivalent (2vHPV), 3 dose schedule, for intramuscular use

2

C0026860::specimen_source_topography_of

specimen_source_topography_of

For which laboratory test is {subj} the specimen source topography?

C0026860

Musculoskeletal System

C0586570

Excised tendon specimen

Entire subcutaneous tissue of lower extremity

Excised tendon specimen

Retinaculum of flexor muscles

Structure of fascia of upper extremity

1

C0040300::specimen_source_topography_of

specimen_source_topography_of

For which laboratory test is {subj} the specimen source topography?

C0040300

Body tissue

C1292587

Specimen from large intestine obtained by incisional biopsy

Small intestine mucous membrane

Specimen from large intestine obtained by incisional biopsy

Entire appendiceal mucous membrane

Structure of subserous tissue of parietal peritoneum

1

C0042232::specimen_source_topography_of

specimen_source_topography_of

For which laboratory test is {subj} the specimen source topography?

C0042232

Vagina

C1301220

Specimen from vagina obtained by partial vaginectomy

Structure of uterine tubal epithelium

Entire subcutaneous tissue of lower margin of nasal septum

Specimen from vagina obtained by partial vaginectomy

Entire subcutaneous tissue of vulva

2

C0032385::structural_class_of

structural_class_of

For which entity is {subj} the structural class?

C0032385

Pollen

C2723639

dogfennel pollen extract

Adansonia digitata fruit extract

Yucca schidigera extract

dog hair extract / English plantain pollen extract

dogfennel pollen extract

3

C0282564::structural_class_of

structural_class_of

For which entity is {subj} the structural class?

C0282564

Anthracyclines

C0020789

idarubicin

amifostine

idarubicin

amifampridine

miocamycin

1