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ed8c380548711439b51d4f03fc6f2b62ee223abb50c7604237657c1b46d5e4dd.png
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<table><tr><td> </td><td colspan="2">All</td><td colspan="3">Girls</td><td colspan="3">Boys</td></tr><tr><td> </td><td>OW</td><td>NW</td><td>All</td><td>OW</td><td>NW</td><td>All</td><td>OW</td><td>NW</td></tr><tr><td>n</td><td>94</td><td>51</td><td>78</td><td>54</td><td>24</td><td>67</td><td>40</td><td>27</td></tr><tr><td>Age (years)</td><td>7.6 &#177; 1.1</td><td>7.3 &#177; 1.1</td><td>7.5 &#177; 1.1</td><td>7.5 &#177; 1.1</td><td>7.5 &#177; 1.2</td><td>7.5 &#177; 1.0</td><td>7.7 &#177; 1.0</td><td>7.2 &#177; 0.9<sup>c</sup></td></tr><tr><td>Ethnicity (%)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> caucasian</td><td>70</td><td>73</td><td>68</td><td>69</td><td>67</td><td>75</td><td>73</td><td>77.8</td></tr><tr><td> asiatic</td><td>30</td><td>25</td><td>31</td><td>31</td><td>29</td><td>25</td><td>27</td><td>22.2</td></tr><tr><td> black</td><td>-</td><td>2</td><td>1</td><td>-</td><td>4</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Graduation mothers (%)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> &lt; 10 years</td><td>28</td><td>20</td><td>24</td><td>26</td><td>21</td><td>25</td><td>30</td><td>18</td></tr><tr><td> = 10 years</td><td>23</td><td>35</td><td>33</td><td>30</td><td>42</td><td>21</td><td>15</td><td>30</td></tr><tr><td> &gt; 10 years</td><td>49</td><td>45</td><td>42</td><td>44</td><td>37</td><td>54</td><td>55</td><td>52</td></tr><tr><td>Graduation fathers (%)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> &lt; 10 years</td><td>31</td><td>31</td><td>29</td><td>26</td><td>38</td><td>33</td><td>38</td><td>26</td></tr><tr><td> = 10 years</td><td>25</td><td>22</td><td>21</td><td>26</td><td>8</td><td>28</td><td>25</td><td>33</td></tr><tr><td> &gt; 10 years</td><td>44</td><td>47</td><td>50</td><td>48</td><td>54</td><td>39</td><td>37</td><td>41</td></tr><tr><td>Primary attachment figure (%)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> Mother</td><td>76</td><td>75</td><td>77</td><td>74</td><td>83.3</td><td>74</td><td>79</td><td>67</td></tr><tr><td> Father</td><td>2</td><td>6</td><td>4</td><td>4</td><td>4.2</td><td>3</td><td>0</td><td>8</td></tr><tr><td> Others</td><td>22</td><td>19</td><td>19</td><td>22</td><td>12.5</td><td>23</td><td>21</td><td>25</td></tr><tr><td>Mothers&#8217; BMI (kg/m<sup>2</sup>)</td><td>27.6 &#177; 6.5</td><td>23.6 &#177; 4.0<sup>a</sup></td><td>26.6 &#177; 6.1</td><td>27.3 &#177; 6.6</td><td>24.9 &#177; 4.7</td><td>25.7 &#177; 6.0</td><td>27.9 &#177; 6.6</td><td>22.5 &#177; 2.8<sup>c</sup></td></tr><tr><td>Fathers&#8217; BMI (kg/m<sup>2</sup>)</td><td>28.8 &#177; 4.9</td><td>27.3 &#177; 3.8</td><td>28.3 &#177; 4.8</td><td>29.0 &#177; 5.0</td><td>26.9 &#177; 3.9</td><td>28.2 &#177; 4.4</td><td>28.5 &#177; 4.8</td><td>27.7 &#177; 3.8</td></tr><tr><td> Weight (kg)</td><td>36.1 &#177; 7.2</td><td>26.7 &#177; 3.9<sup>a</sup></td><td>33.0 &#177; 7.2</td><td>35.3 &#177; 7.1</td><td>27.9 &#177; 4.2<sup>b</sup></td><td>32.5 &#177; 8.3</td><td>37.1 &#177; 7.4</td><td>25.5 &#177; 3.4<sup>c,d</sup></td></tr><tr><td> Height (m)</td><td>1.30 &#177; 0.1</td><td>1.26 &#177; 0.07<sup>a</sup></td><td>1.29 &#177; 0.09</td><td>1.29 &#177; 0.1</td><td>1.28 &#177; 0.07</td><td>1.28 &#177; 0.09</td><td>1.31 &#177; 0.09</td><td>1.24 &#177; 0.07<sup>c,d</sup></td></tr><tr><td>BMI (kg/m<sup>2</sup>)</td><td>21.2 &#177; 2.1</td><td>16.8 &#177; 1.2<sup>a</sup></td><td>19.8 &#177; 2.6</td><td>21.0 &#177; 2.1</td><td>17.0 &#177; 1.4<sup>b</sup></td><td>19.4 &#177; 3.0</td><td>21.4 &#177; 2.1</td><td>16.5 &#177; 1.0<sup>c</sup></td></tr><tr><td> BMI-SDS</td><td>1.89 &#177; 0.47</td><td>0.44 &#177; 0.58<sup>a</sup></td><td>1.41 &#177; 0.81</td><td>1.81 &#177; 0.47</td><td>0.50 &#177; 0.67<sup>b</sup></td><td>1.35 &#177; 0.93</td><td>2.00 &#177; 0.46<sup>b</sup></td><td>0.38 &#177; 0.48<sup>c</sup></td></tr></table>
63cfb2199319efa91aa8c7fb120e2932957abe4d51e7d10b0519563ffa083c14.png
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<table><tr><td rowspan="2"> </td><td>High level FK778</td><td>Mid level FK778</td><td>Low level FK77</td><td>MMF</td></tr><tr><td>N = 87</td><td>N = 92</td><td>N = 92</td><td>N = 93</td></tr><tr><td>Anemia</td><td>37 (42.5)</td><td>42 (45.7)</td><td>36 (39.1)</td><td>35 (37.6)</td></tr><tr><td>Leukopenia</td><td>7 (8)</td><td>11 (12)</td><td>6 (6.5)</td><td>13 (14)</td></tr><tr><td>Thrombocytopenia<sup>a</sup></td><td>9 (10.3)</td><td>4 (4.3)</td><td>11 (12)</td><td>2 (2.2)</td></tr><tr><td>Diarrhea</td><td>14 (16.1)</td><td>20 (21.7)</td><td>16 (17.4)</td><td>23 (24.7)</td></tr><tr><td>Constipation</td><td>15 (17.2)</td><td>8 (8.7)</td><td>7 (7.6)</td><td>17 (18.3)</td></tr><tr><td>Nausea</td><td>9 (10.3)</td><td>5 (5.4)</td><td>6 (6.5)</td><td>9 (9.7)</td></tr><tr><td>Vomiting</td><td>11 (12.6)</td><td>12 (13)</td><td>7 (7.6)</td><td>11 (11.8)</td></tr><tr><td>Peripheral edema</td><td>13 (14.9)</td><td>17 (18.5)</td><td>15 (16.3)</td><td>12 (12.9)</td></tr><tr><td>Chest pain<sup>b</sup></td><td>9 (10.3)</td><td>2 (2.2)</td><td>2 (2.2)</td><td>2 (2.2)</td></tr><tr><td>Bacterial urinary tract infection</td><td>19 (21.8)</td><td>29 (31.5)</td><td>28 (30.4)</td><td>27 (29)</td></tr><tr><td>Cytomegalovirus infection</td><td>4 (4.6)</td><td>5 (5.4)</td><td>9 (9.8)</td><td>10 (10.8)</td></tr><tr><td>Hypocalcaemia</td><td>13 (14.9)</td><td>13 (14.1)</td><td>12 (13)</td><td>9 (9.7)</td></tr><tr><td>Hyperglycemia</td><td>11 (12.6)</td><td>15 (16.3)</td><td>10 (10.9)</td><td>10 (10.8)</td></tr><tr><td>Hyperlipidemia</td><td>5 (5.7)</td><td>4 (4.3)</td><td>2 (2.2)</td><td>11 (11.8)</td></tr><tr><td>Hypokalemia</td><td>15 (17.2)</td><td>10 (10.9)</td><td>12 (13)</td><td>7 (7.5)</td></tr><tr><td>Hypoalbuminemia<sup>c</sup></td><td>5 (5.7)</td><td>0</td><td>1 (1.1)</td><td>0</td></tr><tr><td>Hyperuricemia</td><td>9 (10.3)</td><td>21 (22.8)</td><td>20 (21.7)</td><td>12 (12.9)</td></tr><tr><td>Headache</td><td>11 (12.6)</td><td>11 (12)</td><td>9 (9.8)</td><td>4 (4.3)</td></tr><tr><td>Tremor</td><td>9 (10.3)</td><td>12 (13)</td><td>9 (9.8)</td><td>14 (15.1)</td></tr><tr><td>Insomnia</td><td>4 (4.6)</td><td>3 (3.3)</td><td>4 (4.3)</td><td>10 (10.8)</td></tr><tr><td>Hypertension</td><td>20 (23)</td><td>16 (17.4)</td><td>20 (21.7)</td><td>25 (26.9)</td></tr></table>
461050bb70009336fcd9e79f6a1be4314043985c6597c4b4635237f3c399f0b3.png
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<table><tr><td rowspan="3">Characteristic</td><td colspan="5">Training set (<i>n</i> = 142)</td><td colspan="5">Validation set (<i>n</i> = 112)</td></tr><tr><td colspan="2">Patients</td><td colspan="3">B4GALT1 expression</td><td colspan="2">Patients</td><td colspan="3">B4GALT1 expression</td></tr><tr><td>NO.</td><td>%</td><td>Low</td><td>High</td><td><i>P</i></td><td>NO.</td><td>%</td><td>Low</td><td>High</td><td><i>P</i></td></tr><tr><td>Age, years</td><td></td><td></td><td></td><td></td><td>0.614</td><td></td><td></td><td></td><td></td><td>0.763</td></tr><tr><td> Mean &#177; SD</td><td>62.4 &#177; 10.8</td><td></td><td>61.8 &#177; 10.9</td><td>62.7 &#177; 10.8</td><td></td><td>61.5 &#177; 8.7</td><td></td><td>61.8 &#177; 9.7</td><td>61.3 &#177; 7.6</td><td></td></tr><tr><td> Range, median</td><td>30&#8211;82,62</td><td></td><td>34&#8211;82,62</td><td>30&#8211;82,62</td><td></td><td>35&#8211;81,62</td><td></td><td>35&#8211;81,62</td><td>46&#8211;75,61</td><td></td></tr><tr><td>Gender</td><td></td><td></td><td></td><td></td><td>0.925</td><td></td><td></td><td></td><td></td><td>0.581</td></tr><tr><td> Male</td><td>118</td><td>83.1</td><td>45</td><td>73</td><td></td><td>97</td><td>86.6</td><td>48</td><td>49</td><td></td></tr><tr><td> Female</td><td>24</td><td>16.9</td><td>10</td><td>14</td><td></td><td>15</td><td>13.4</td><td>9</td><td>6</td><td></td></tr><tr><td>Tumor size, cm</td><td></td><td></td><td></td><td></td><td>0.053</td><td></td><td></td><td></td><td></td><td>0.411</td></tr><tr><td> Mean &#177; SD</td><td>3.8 &#177; 1.9</td><td></td><td>4.2 &#177; 2.1</td><td>3.6 &#177; 1.7</td><td></td><td>3.8 &#177; 1.8</td><td></td><td>3.9 &#177; 2.0</td><td>3.7 &#177; 1.6</td><td></td></tr><tr><td> Range</td><td>0.5&#8211;10.0</td><td></td><td>1.0&#8211;10.0</td><td>0.5&#8211;8.0</td><td></td><td>0.8&#8211;9.5</td><td></td><td>0.8&#8211;9.5</td><td>1.3&#8211;9.0</td><td></td></tr><tr><td>pT stage</td><td></td><td></td><td></td><td></td><td>0.971</td><td></td><td></td><td></td><td></td><td>0.720</td></tr><tr><td> T2</td><td>68</td><td>47.9</td><td>27</td><td>41</td><td></td><td>49</td><td>43.8</td><td>27</td><td>22</td><td></td></tr><tr><td> T3</td><td>48</td><td>33.8</td><td>18</td><td>30</td><td></td><td>49</td><td>43.8</td><td>23</td><td>26</td><td></td></tr><tr><td> T4</td><td>26</td><td>18.3</td><td>10</td><td>16</td><td></td><td>14</td><td>12.4</td><td>7</td><td>7</td><td></td></tr><tr><td>Grade</td><td></td><td></td><td></td><td></td><td>0.017</td><td></td><td></td><td></td><td></td><td>0.950</td></tr><tr><td> low</td><td>24</td><td>16.9</td><td>15</td><td>9</td><td></td><td>11</td><td>9.8</td><td>6</td><td>5</td><td></td></tr><tr><td> high</td><td>118</td><td>83.1</td><td>40</td><td>78</td><td></td><td>101</td><td>90.2</td><td>51</td><td>50</td><td></td></tr><tr><td>LVI</td><td></td><td></td><td></td><td></td><td>0.157</td><td></td><td></td><td></td><td></td><td>0.741</td></tr><tr><td> absent</td><td>53</td><td>37.3</td><td>25</td><td>28</td><td></td><td>78</td><td>69.6</td><td>41</td><td>37</td><td></td></tr><tr><td> present</td><td>89</td><td>62.7</td><td>30</td><td>59</td><td></td><td>34</td><td>30.4</td><td>16</td><td>18</td><td></td></tr><tr><td>CCI</td><td></td><td></td><td></td><td></td><td>0.116</td><td></td><td></td><td></td><td></td><td>0.263</td></tr><tr><td>&#8804; 1</td><td>47</td><td>33.1</td><td>23</td><td>24</td><td></td><td>44</td><td>39.3</td><td>19</td><td>25</td><td></td></tr><tr><td>&#8805; 2</td><td>95</td><td>66.9</td><td>32</td><td>63</td><td></td><td>68</td><td>60.7</td><td>38</td><td>30</td><td></td></tr></table>
d95171919f09af032301566c15e5d47049e6a49d72549c013f1d9957143f562d.png
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<table><tr><td>Composition</td><td>CAS</td><td>RP-A</td><td>RP-E</td></tr><tr><td>Moisture</td><td>9.7</td><td>9.8</td><td>10.9</td></tr><tr><td>Protein</td><td>87.3</td><td>86.4</td><td>79.6</td></tr><tr><td>Carbohydrate</td><td>0.2</td><td>0.9</td><td>2.5</td></tr><tr><td>Lipids</td><td>0.5</td><td>0.8</td><td>0.8</td></tr><tr><td>Ash</td><td>1.7</td><td>1.0</td><td>1.5</td></tr><tr><td>Dietary fiber</td><td>0.6</td><td>1.1</td><td>4.7</td></tr></table>
ade8171aa3c4a69305b8eb2b6a277a65e03fba578e1304bab2ca20545f4d1b2e.png
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<table><tr><td>Design</td><td>Intervention</td><td>Country</td><td>Focus</td><td>Sample</td><td>Sample size(n)</td><td>Duration</td><td>Reference</td></tr><tr><td>Cluster blind RCT</td><td>Electronic decision support system</td><td>USA</td><td>GP</td><td>T1D, T2D</td><td>639</td><td>21 months</td><td>[15]</td></tr><tr><td>Cluster RCT</td><td>Diabetes register</td><td>UK</td><td>GP</td><td>T2D</td><td>3, 608</td><td>15 months</td><td>[16]</td></tr><tr><td>Cluster RCT</td><td>Diabetes register</td><td>USA</td><td>GP</td><td>T2D</td><td>7, 101</td><td>12 months</td><td>[17]</td></tr><tr><td>Cluster RCT</td><td>Electronic telemedicine</td><td>USA</td><td>Patient</td><td>T2D</td><td>1, 665</td><td>12 months</td><td>[18]</td></tr><tr><td>Cluster RCT</td><td>Electronic telemedicine</td><td>USA</td><td>GP</td><td>T2D</td><td>1, 665</td><td>12 months</td><td>[19]</td></tr><tr><td>Cluster RCT</td><td>Electronic self-management system</td><td>USA</td><td>Patient</td><td>T2D</td><td>886</td><td>12 months</td><td>[20]</td></tr><tr><td>RCT</td><td>Electronic self-management system</td><td>USA</td><td>Patient</td><td>T1D, T2D</td><td>122</td><td>6 months</td><td>[21]</td></tr><tr><td>RCT</td><td>Electronic self-management system</td><td>USA</td><td>Patient</td><td>T1D, T2D</td><td>104</td><td>12 months</td><td>[22]</td></tr><tr><td>RCT</td><td>Electronic self-management system</td><td>USA</td><td>Patient</td><td>T1D, T2D</td><td>62</td><td>6 months</td><td>[23]</td></tr><tr><td>Nonrandomised cluster control trial</td><td>Electronic management system</td><td>USA</td><td>GP</td><td>T1D, T2D</td><td>6, 646</td><td>24 months</td><td>[24]</td></tr><tr><td>Nonrandomised control trial</td><td>Diabetes register</td><td>USA</td><td>GP</td><td>T1D, T2D</td><td>898</td><td>20 months</td><td>[25]</td></tr><tr><td>Nonrandomised control trial</td><td>Personal Digital Assistant (PDA) based electronic management system</td><td>USA</td><td>GP</td><td>T2D</td><td>173</td><td>16 months</td><td>[26]</td></tr><tr><td>Nonrandomised control trial</td><td>Diabetes register</td><td>USA</td><td>GP</td><td>T1D, T2D</td><td>661</td><td>2 years</td><td>[27]</td></tr><tr><td>Nonrandomised control trial</td><td>Electronic decision support system</td><td>USA</td><td>GP</td><td>T1D, T2D</td><td>16</td><td>6 months</td><td>[28]</td></tr><tr><td>Single sample before and after design</td><td>Diabetes register</td><td>USA</td><td>GP</td><td>T1D, T2D</td><td>62</td><td>3 years</td><td>[29]</td></tr><tr><td>Single sample before and after design</td><td>Diabetes register</td><td>Korea</td><td>GP</td><td>T1D, T2D</td><td>185</td><td>3 months</td><td>[30]</td></tr></table>
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<table><tr><td> </td><td>Amplitude of extension reflex score &lt; 2.5</td><td>Rotarod time on rod &lt; 90 s</td><td>Symmetry of extension reflex score &lt; 1</td><td>Stride length &lt; 5 cm</td></tr><tr><td>hA30P&#945;-syn+/+</td><td>18.1 &#177; 0.2 months</td><td>19.3 &#177; 0.2 months</td><td>20.0 &#177; 0.2 months</td><td>20.7 &#177; 0.2 months</td></tr><tr><td><i>parkin</i>+/-; hA30P&#945;-syn+/+</td><td>18.4 &#177; 0.2 months</td><td>20.2 &#177; 0.2 months</td><td>22.3 &#177; 0.2 months</td><td>23.0 &#177; 0.2 months</td></tr><tr><td><i>parkin</i>-/-; hA30P&#945;-syn+/+</td><td>21.0 &#177; 0.2 months</td><td>23.2 &#177; 0.2 months</td><td>23.4 &#177; 0.2 months</td><td>&gt; 24 months</td></tr></table>
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<table><tr><td></td><td colspan="8">%</td></tr><tr><td></td><td>Arthritis</td><td>Stroke</td><td>Angina</td><td>Diabetes</td><td>Lung disease</td><td>Asthma</td><td>Depression</td><td>Cataracts</td></tr><tr><td>No hypertension</td><td>18.30</td><td>1.13</td><td>5.85</td><td>4.55</td><td>3.33</td><td>3.16</td><td>3.76</td><td>2.78</td></tr><tr><td>Hypertension diagnosed and measured</td><td>35.61</td><td>8.91</td><td>6.25</td><td>21.44</td><td>4.02</td><td>7.35</td><td>3.63</td><td>8.92</td></tr><tr><td>Hypertension measured but not diagnosed</td><td>18.83</td><td>2.24</td><td>3.43</td><td>4.32</td><td>1.54</td><td>3.05</td><td>1.40</td><td>1.18</td></tr><tr><td>Normal blood pressure but diagnosed with hypertension</td><td>38.90</td><td>3.91</td><td>12.32</td><td>15.65</td><td>7.72</td><td>14.43</td><td>7.55</td><td>12.56</td></tr></table>
39350272ff1fd918e74a5511e69e31cbbcffe0e5780309fda3e6feabf668053f.png
simple
<table><tr><td>Outcome</td><td>Impact of Statins on rate of events modeled using Cox Proportional Hazards (HR, 95% CI) (Statin versus No Statin)</td><td>Impact of Statins on number of events, modeled using Generalized Linear Models (RR, 95% CI) (Statin versus No Statin)</td></tr><tr><td>All-cause re-hospitalizations</td><td></td><td></td></tr><tr><td>Modeled without propensity score</td><td>0.84 (0.78-0.90)</td><td>0.97 (0.90-1.04)</td></tr><tr><td>Modeled with propensity score</td><td>0.98 (0.91-1.06)</td><td>1.04 (0.97-1.12)</td></tr><tr><td>CVD re-hospitalizations</td><td></td><td></td></tr><tr><td>Modeled without propensity score</td><td>0.98 (0.90-1.07)</td><td>0.90 (0.86-1.12)</td></tr><tr><td>Modeled with propensity score</td><td>1.11 (1.02-1.22)</td><td>1.03 (0.92-1.16)</td></tr><tr><td>All physician visits</td><td>N/A</td><td></td></tr><tr><td>Modeled without propensity score</td><td></td><td>0.84 (0.79-0.88)</td></tr><tr><td>Modeled with propensity score</td><td></td><td>0.97 (0.92-1.02)</td></tr><tr><td>CVD-related physician visits</td><td>N/A</td><td></td></tr><tr><td>Modeled without propensity score</td><td></td><td>1.18 (1.09-1.29)</td></tr><tr><td>Modeled with propensity score</td><td></td><td>1.34 (1.23-1.46)</td></tr><tr><td>Coronary Revascularizations</td><td></td><td>N/A</td></tr><tr><td>Modeled without propensity score</td><td>1.55 (1.30-1.84)</td><td></td></tr><tr><td>Modeled with propensity score</td><td>1.15 (0.97-1.36)</td><td></td></tr><tr><td>Mortality</td><td></td><td>N/A</td></tr><tr><td>Modeled without propensity score</td><td>0.41 (0.35-0.49)</td><td></td></tr><tr><td>Modeled with propensity score</td><td>0.74 (0.63-0.88)</td><td></td></tr></table>
ec76d8c1a534d1782f465732b1d17e39757708f4c6560e492661c7d922d6f1db.png
complex
<table><tr><td rowspan="2">Variables</td><td rowspan="2">Category</td><td colspan="2">TB status</td><td rowspan="2">p value</td></tr><tr><td>No (N = 520)</td><td>Yes (N = 130)</td></tr><tr><td colspan="2">Age in year, mean &#177; std. error of mean</td><td>33.6 &#177; 0.4</td><td>33.4 &#177; 0.8</td><td>0.850</td></tr><tr><td rowspan="2">Gender</td><td>Male, N (%)</td><td>165 (31.7)</td><td>56 (43.1)</td><td>0.017</td></tr><tr><td>Female, N (%)</td><td>355 (68.3)</td><td>74 (56.9)</td><td></td></tr><tr><td rowspan="2">Residence</td><td>Rural, N (%)</td><td>125 (24)</td><td>35 (26.9)</td><td>0.569</td></tr><tr><td>Urban, N (%)</td><td>395 (76)</td><td>95 (73.1)</td><td></td></tr><tr><td rowspan="2">Marital status</td><td>Never married N (%)</td><td>102 (19.6)</td><td>26 (20.0)</td><td>0.160</td></tr><tr><td>Ever married, N (%)</td><td>418 (80.4)</td><td>104 (80.0)</td><td></td></tr><tr><td rowspan="4">Educational level</td><td>Illiterate, N (%)</td><td>102 (19.6)</td><td>37 (28.5)</td><td>0.168</td></tr><tr><td>Primary, N (%)</td><td>183 (35.2)</td><td>39 (30)</td><td></td></tr><tr><td>Secondary, N (%)</td><td>175 (33.7)</td><td>39 (30)</td><td></td></tr><tr><td>Tertiary, N (%)</td><td>60 (11.5)</td><td>15 (11.5)</td><td></td></tr><tr><td rowspan="2">Employment status</td><td>Unemployed, N (%)</td><td>350 (67.3)</td><td>91 (70.0)</td><td>0.257</td></tr><tr><td>Employed, N (%)</td><td>170 (33.7)</td><td>39 (30.0)</td><td></td></tr><tr><td rowspan="2">Drug addiction behavior</td><td>No, N (%)</td><td>246 (47.3)</td><td>57 (43.8)</td><td>0.479</td></tr><tr><td>Yes, N (%)</td><td>274 (52.7)</td><td>73 (56.2)</td><td></td></tr><tr><td colspan="2">Weight in kg, mean &#177; std. error of mean</td><td>52.0 &#177; 0.4</td><td>49.1 &#177; 0.8</td><td>0.003</td></tr><tr><td colspan="2">CD4 in cells/mm<sup>3</sup>, mean &#177; std. error of mean</td><td>153.8 &#177; 3.8</td><td>128.7 &#177; 9.7</td><td>0.006</td></tr><tr><td colspan="2">BMI in kg/m<sup>2</sup>, mean &#177; std. error of mean</td><td>19.4 &#177; 0.1</td><td>18.2 &#177; 0.3</td><td>&lt;0.001</td></tr><tr><td colspan="2">Hgb mg/dl, mean &#177; std. error of mean</td><td>12.3 &#177; 0.1</td><td>11.03 &#177; 0.2</td><td>&lt;0.001</td></tr><tr><td rowspan="3">WHO clinical stage</td><td>Stage I/II, N (%)</td><td>334 (64.2)</td><td>0 (0)</td><td>&lt;0.001</td></tr><tr><td>Stage III, N (%)</td><td>157 (30.2)</td><td>85 (65.4)</td><td></td></tr><tr><td>Stage IV, N (%)</td><td>29 (5.6)</td><td>45 (34.6)</td><td></td></tr><tr><td rowspan="2">ART regimen</td><td>Non TDF based, N (%)</td><td>325 (63.3)</td><td>76 (59.2)</td><td>&lt;0.001</td></tr><tr><td>TDF-based, N (%)</td><td>196 (37.7)</td><td>53 (40.8)</td><td></td></tr><tr><td rowspan="3">Functional status</td><td>Working, N (%)</td><td>378 (72.7)</td><td>51 (38.7)</td><td>&lt;0.001</td></tr><tr><td>Ambulatory, N (%)</td><td>127 (24.4)</td><td>66 (50.8)</td><td></td></tr><tr><td>Bed ridden, N (%)</td><td>15 (2.9)</td><td>13 (10)</td><td></td></tr></table>
ac76c4220634f112e22c278258c10063a14bbfd537e5a41974b3d9292475a2db.png
complex
<table><tr><td rowspan="2" colspan="2">Locus</td><td colspan="9">Sample localities</td></tr><tr><td>11&#176;N</td><td>9&#176;N</td><td>GAR<sup>a</sup></td><td>7&#176;S</td><td>11&#176;S</td><td>17&#176;S</td><td>23&#176;S</td><td>32&#176;S</td><td>38&#176;S</td></tr><tr><td rowspan="4"><i>16S</i> rRNA encoding gene(300 bp)</td><td><i>N</i><sup><i>b</i></sup></td><td>-</td><td>13,310</td><td>-</td><td>2008</td><td>7531</td><td>6688</td><td>1899</td><td>6400</td><td>3046</td></tr><tr><td><i>h</i><sup><i>c</i></sup></td><td>-</td><td>7</td><td>-</td><td>3</td><td>6</td><td>6</td><td>3</td><td>4</td><td>5</td></tr><tr><td><i>H</i><sup><i>d</i></sup></td><td>-</td><td>0.030</td><td>-</td><td>0.157</td><td>0.020</td><td>0.029</td><td>0.026</td><td>0.009</td><td>0.029</td></tr><tr><td><i>&#960;</i><sup><i>e</i></sup></td><td>-</td><td>1.0E-04</td><td>-</td><td>5.3E-04</td><td>6.6E-05</td><td>9.5E-05</td><td>8.7E-05</td><td>3.0E-05</td><td>9.8E-05</td></tr><tr><td rowspan="4"><i>COI</i> Cytochrome C oxidase subunit I(443 bp)</td><td><i>N</i></td><td>3294</td><td>3692</td><td>1583</td><td>2246</td><td>2157</td><td>2545</td><td>1029</td><td>2332</td><td>737</td></tr><tr><td><i>h</i></td><td>36</td><td>24</td><td>40</td><td>8</td><td>11</td><td>59</td><td>17</td><td>33</td><td>19</td></tr><tr><td><i>H</i></td><td>0.80</td><td>0.70</td><td>0.72</td><td>0.77</td><td>0.68</td><td>0.86</td><td>0.84</td><td>0.67</td><td>0.73</td></tr><tr><td><i>&#960;</i></td><td>0.003</td><td>0.002</td><td>0.003</td><td>0.003</td><td>0.002</td><td>0.003</td><td>0.004</td><td>0.002</td><td>0.003</td></tr><tr><td rowspan="4"><i>dnaK</i> Chaperone protein(469 bp)</td><td><i>N</i></td><td>2465</td><td>3100</td><td>2995</td><td>2362</td><td>2671</td><td>1876</td><td>1967</td><td>2367</td><td>2300</td></tr><tr><td><i>h</i></td><td>5</td><td>39</td><td>23</td><td>22</td><td>19</td><td>45</td><td>4</td><td>33</td><td>43</td></tr><tr><td><i>H</i></td><td>0.42</td><td>0.78</td><td>0.62</td><td>0.80</td><td>0.67</td><td>0.65</td><td>0.45</td><td>0.82</td><td>0.83</td></tr><tr><td><i>&#960;</i></td><td>0.001</td><td>0.003</td><td>0.002</td><td>0.003</td><td>0.002</td><td>0.002</td><td>0.001</td><td>0.003</td><td>0.003</td></tr><tr><td rowspan="4"><i>pgi</i> Glucose-6-phosphate isomerase(441 bp)</td><td><i>N</i></td><td>1966</td><td>2986</td><td>2466</td><td>1972</td><td>1918</td><td>2668</td><td>1339</td><td>3747</td><td>1528</td></tr><tr><td><i>h</i></td><td>35</td><td>30</td><td>57</td><td>16</td><td>16</td><td>70</td><td>11</td><td>151</td><td>103</td></tr><tr><td><i>H</i></td><td>0.82</td><td>0.85</td><td>0.85</td><td>0.67</td><td>0.70</td><td>0.87</td><td>0.46</td><td>0.91</td><td>0.91</td></tr><tr><td><i>&#960;</i></td><td>0.004</td><td>0.004</td><td>0.004</td><td>0.003</td><td>0.003</td><td>0.004</td><td>0.002</td><td>0.008</td><td>0.006</td></tr><tr><td rowspan="4"><i>pykF</i> Pyruvate kinase(404 bp)</td><td><i>N</i></td><td>2234</td><td>3051</td><td>3475</td><td>2770</td><td>3020</td><td>2629</td><td>1602</td><td>3150</td><td>1934</td></tr><tr><td><i>h</i></td><td>39</td><td>37</td><td>57</td><td>32</td><td>65</td><td>43</td><td>21</td><td>87</td><td>39</td></tr><tr><td><i>H</i></td><td>0.75</td><td>0.81</td><td>0.77</td><td>0.74</td><td>0.90</td><td>0.79</td><td>0.79</td><td>0.88</td><td>0.78</td></tr><tr><td><i>&#960;</i></td><td>0.003</td><td>0.006</td><td>0.005</td><td>0.006</td><td>0.006</td><td>0.003</td><td>0.004</td><td>0.006</td><td>0.003</td></tr><tr><td rowspan="4"><i>rpoD</i> RNA polymerase, sigma D factor(388 bp)</td><td><i>N</i></td><td>3326</td><td>4328</td><td>3901</td><td>3650</td><td>4090</td><td>3717</td><td>2403</td><td>4797</td><td>2199</td></tr><tr><td><i>h</i></td><td>30</td><td>26</td><td>25</td><td>26</td><td>22</td><td>42</td><td>27</td><td>18</td><td>42</td></tr><tr><td><i>H</i></td><td>0.84</td><td>0.76</td><td>0.81</td><td>0.80</td><td>0.80</td><td>0.64</td><td>0.70</td><td>0.65</td><td>0.68</td></tr><tr><td><i>&#960;</i></td><td>0.004</td><td>0.003</td><td>0.004</td><td>0.004</td><td>0.004</td><td>0.002</td><td>0.004</td><td>0.002</td><td>0.003</td></tr><tr><td rowspan="4"><i>soxA</i> Sulfur oxidation protein A(361 bp)</td><td><i>N</i></td><td>4196</td><td>5036</td><td>4085</td><td>3763</td><td>4652</td><td>3370</td><td>2715</td><td>3879</td><td>4105</td></tr><tr><td><i>h</i></td><td>6</td><td>9</td><td>12</td><td>7</td><td>3</td><td>5</td><td>8</td><td>4</td><td>6</td></tr><tr><td><i>H</i></td><td>0.45</td><td>0.70</td><td>0.70</td><td>0.47</td><td>&lt;0.01</td><td>0.34</td><td>0.03</td><td>0.03</td><td>0.17</td></tr><tr><td><i>&#960;</i></td><td>0.001</td><td>0.001</td><td>0.002</td><td>0.001</td><td>&lt;0.001</td><td>0.001</td><td>&lt;0.001</td><td>&lt;0.001</td><td>&lt;0.001</td></tr></table>
1db4c93d867bf40bc685ab4688a8e3c7e1f0b12a196e66af215dbb7ea29c8e8a.png
simple
<table><tr><td></td><td>Age &lt;75 years</td><td>Age &#8805;75 years</td><td><i>p</i></td></tr><tr><td>Histological grade (well/mod/poor)</td><td>54 (35.8 %)/83 (55.0 %)/14 (9.2 %)</td><td>19 (35.8 %)/28 (52.8 %)/6 (11.4 %)</td><td>0.99</td></tr><tr><td>Lymphatic invasion (no/yes)</td><td>6 (4.0 %)/145 (96.0 %)</td><td>6 (11.3 %)/47 (88.7 %)</td><td>0.02</td></tr><tr><td>Vessel invasion (no/yes)</td><td>20 (13.2 %)/131 (86.8 %)</td><td>7 (13.2 %)/46 (86.8 %)</td><td>0.99</td></tr><tr><td>Operation time (min)</td><td>480 (80&#8211;713)</td><td>241 (74&#8211;645)</td><td>0.35</td></tr><tr><td>Blood loss (g)</td><td>185 (10&#8211;1400)</td><td>129 (20&#8211;510)</td><td>0.07</td></tr><tr><td>Laparoscopic surgery (no/yes)</td><td>83 (55.0 %)/69 (45.0 %)</td><td>31 (58.5 %)/22 (41.5 %)</td><td>0.62</td></tr><tr><td>Composite resection (no/yes)</td><td>143 (94.7 %)/8 (5.3 %)</td><td>48 (90.6 %)/5 (9.4 %)</td><td>0.38</td></tr><tr><td>Postoperative chemotherapy (no/yes)</td><td>36 (23.8 %)/115 (76.2 %)</td><td>32 (60.4 %)/21 (39.6 %)</td><td>&lt;0.01</td></tr><tr><td>Postoperative complication (no/yes)</td><td>95 (62.9 %)/56 (37.1 %)</td><td>32 (60.4 %)/21 (39.6 %)</td><td>0.74</td></tr><tr><td>Hospital stay (days)</td><td>25.7 (14&#8211;31)</td><td>25.5 (16&#8211;40)</td><td>0.93</td></tr></table>
6de938ccf24ca3a5b7b393c01c04ca02b6513d3f050193cbf5cd320d1c798a6d.png
complex
<table><tr><td colspan="2">Variable</td><td>Mean (SD)</td><td><i>P</i>-value</td></tr><tr><td rowspan="2">Material</td><td>CEM cement</td><td>68* (28)</td><td rowspan="2">0.92</td></tr><tr><td>MTA</td><td>67 (39)</td></tr><tr><td rowspan="4">Subgroups</td><td>AP+GP</td><td>55 (28)</td><td rowspan="4">0.005</td></tr><tr><td>AP+TO</td><td>67 (14)</td></tr><tr><td>Obturation with AP material</td><td>56 (29)</td></tr><tr><td>Unfilled</td><td>96 (37)</td></tr></table>
b971fdae6b3fc80fce63c51f4f6b668991e383285b78a0b7a18d90402a65c4cc.png
simple
<table><tr><td> </td><td>Komfo-Anokye (disclosure intervention)</td><td>Korle-Bu (usual care)</td><td> </td><td>Total</td></tr><tr><td> </td><td><i>N</i> = 131(%)</td><td><i>N</i> = 167(%)</td><td><i>P</i> value</td><td><i>N</i> = 298(%)</td></tr><tr><td>Age<sup>e</sup></td><td>43.2 &#177; 10.8</td><td> 42.1 &#177; 10.0</td><td>0.34<sup>a</sup></td><td>42.6 &#177; 10.4</td></tr><tr><td>Marital status<sup>c</sup></td><td> </td><td> </td><td>0.09<sup>b</sup></td><td> </td></tr><tr><td> Single</td><td>17 (13.0)</td><td>22 (13.2)</td><td> </td><td>39 (13.1)</td></tr><tr><td> Married</td><td>63 (48.1)</td><td>98 (58.7)</td><td> </td><td>161 (54.0)</td></tr><tr><td> Divorce/separated</td><td>17 (13.0)</td><td>23 (13.8)</td><td> </td><td>40 (13.4)</td></tr><tr><td> Widowed</td><td>34 (26.0)</td><td>24 (14.4)</td><td> </td><td>58 (19.5)</td></tr><tr><td>Gender</td><td> </td><td> </td><td>0.38<sup>b</sup></td><td> </td></tr><tr><td> Male</td><td>22 (16.8)</td><td>36 (21.6)</td><td> </td><td>58 (19.5)</td></tr><tr><td> Female</td><td>109 (83.2)</td><td>131 (78.4)</td><td> </td><td>240 (80.5)</td></tr><tr><td>HIV status</td><td> </td><td> </td><td>0.9<sup>b</sup></td><td> </td></tr><tr><td> No or not sure</td><td>53 (40.8)</td><td>65 (39.6)</td><td> </td><td>118 (40.1)</td></tr><tr><td> Yes</td><td>77 (59.2)</td><td>99 (60.4)</td><td> </td><td>176 (59.9)</td></tr><tr><td>Education</td><td> </td><td> </td><td>&lt;0.0001<sup>b</sup></td><td> </td></tr><tr><td> No school</td><td>17 (13.0)</td><td>30 (18.0)</td><td> </td><td>47 (15.8)</td></tr><tr><td> Elementary education</td><td>96 (73.3)</td><td>71 (42.5)</td><td> </td><td>167 (56.0)</td></tr><tr><td> Secondary and post-secondary education</td><td>18 (13.7)</td><td>66 (39.5)</td><td> </td><td>84 (28.2)</td></tr><tr><td>Employment status</td><td> </td><td> </td><td>0.62<sup>b</sup></td><td> </td></tr><tr><td> Unemployed</td><td>18 (13.8)</td><td>22 (13.3)</td><td> </td><td>40 (13.5)</td></tr><tr><td> Self-employed</td><td>103 (79.2)</td><td>127 (76.5)</td><td> </td><td>230 (77.7)</td></tr><tr><td> Private or government sector employment</td><td>9 (6.9)</td><td>17 (10.2)</td><td> </td><td>26 (8.8)</td></tr><tr><td>Monthly household income (GHS)<sup>d</sup></td><td> </td><td> </td><td>&lt;0.0001<sup>b</sup></td><td> </td></tr><tr><td> &gt;50 per month</td><td>26 (20.2)</td><td>2 (1.2)</td><td> </td><td>28 (9.6)</td></tr><tr><td> 50&#8211;300 per month</td><td>84 (65.1)</td><td>99 (60.7)</td><td> </td><td>183 (62.7)</td></tr><tr><td> &gt;300 per month</td><td>19 (14.7)</td><td>62 (38.0)</td><td> </td><td>81 (27.7)</td></tr><tr><td>Distance from clinic/hospital</td><td> </td><td> </td><td>0.0001<sup>b</sup></td><td> </td></tr><tr><td> 0&#8211;20 kilometers</td><td>98 (75.4)</td><td>90 (53.9)</td><td> </td><td>188 (63.3)</td></tr><tr><td> More than 20 kilometers</td><td>32 (24.6)</td><td>77 (46.1)</td><td> </td><td>109 (36.7)</td></tr><tr><td>Receiving own care at</td><td> </td><td> </td><td>0.56<sup>b</sup></td><td> </td></tr><tr><td> Clinic/hospital</td><td>126 (96.9)</td><td>165 (98.8)</td><td> </td><td>291 (98.0)</td></tr><tr><td> Clinic/hospital and Traditional/homeopathic healer</td><td>2 (1.5)</td><td>1 (0.6)</td><td> </td><td>3 (1.0)</td></tr><tr><td> Other</td><td>2 (1.5)</td><td>1 (0.6)</td><td> </td><td>3 (1.0)</td></tr></table>
1a78c60ad214efbb3c7a66ebc91a97cf25788be04456e5bdaacfb849c1826764.png
simple
<table><tr><td>Author</td><td>GA at diagnosis (weeks)</td><td>Treatment</td><td>Complications</td><td>Follow-up (months)</td><td>Outcome</td></tr><tr><td>Benedetto et al.</td><td>9</td><td>Endoscopy with HCPs</td><td>no</td><td>1</td><td>Normal</td></tr><tr><td>Chen et al.</td><td>31</td><td>Endoscopy with HCPs</td><td>HELLP syndrome</td><td>2</td><td>Normal</td></tr></table>
dddf6728ec0e4a8d25d2dbf48d69ddf3d7f4f5d1fb10eeb10c303822d852084b.png
simple
<table><tr><td>GBR</td><td>Auto only</td><td>Auto + xeno</td><td>Xeno only</td><td>Syn only</td><td>Total</td></tr><tr><td>No</td><td>40</td><td>44</td><td>79</td><td>17</td><td>180</td></tr><tr><td>%</td><td>22.2</td><td>24.4</td><td>43.9</td><td>9.4</td><td>100.0</td></tr></table>
c2d2e8a54767630ced407ec0a393b9d54d81a0fd89c4c18b6ffdc917a762bea5.png
simple
<table><tr><td>Variable</td><td>Biliary acute Pancreatitis (<i>n</i> = 425)</td><td>Hypertriglyceridemia acute Pancreatitis (<i>n</i> = 305)</td><td><i>P</i> value</td></tr><tr><td>Hospital mortality, no.</td><td>36(8.5%)</td><td>24(7.9%)</td><td>0.787</td></tr><tr><td>Need of surgery, no.</td><td>39(9.2%)</td><td>33(10.8%)</td><td>0.529</td></tr><tr><td>ICU admission</td><td>260(61.2%)</td><td>186(61.0%)</td><td>1</td></tr><tr><td>Length of ICU stay, days</td><td>4(2,12)</td><td>4(2,10.5)</td><td>0.975</td></tr><tr><td>Length of hospital stay, days</td><td>9(4,22.5)</td><td>9(5,23)</td><td>0.58</td></tr><tr><td>Cost, Thousand CHY</td><td>48.7(22.8157.8)</td><td>51.0(27.9134.6)</td><td>0.623</td></tr></table>
4084b626ce76aca13307440823d0c8916968377d855af46e33b2df8174d55abb.png
simple
<table><tr><td>Drug</td><td>Disease/disturbance</td><td>Side effect</td></tr><tr><td>Cefradine</td><td>Urinary tract infection</td><td>Hypersensitivity, elevated liver enzyme, diarrhea</td></tr><tr><td>Nitroxoline</td><td>Urinary tract infection</td><td>Gastrointestinal intolerance, urine coloration</td></tr><tr><td>Sulfonamide</td><td>Urinary tract infection</td><td>Hypersensitivity, folic acid deficiency, hematological abnormality</td></tr><tr><td>Levofloxacin</td><td>Urinary tract infection</td><td>Diarrhea, tendinitis, seizure neuropathy, elevated liver enzyme</td></tr><tr><td>Atenolol</td><td>Hypertension</td><td>Bradycardia, cough, Raynaud's syndrome</td></tr><tr><td>Amlodipine</td><td>Hypertension</td><td>Flush, tachycardia, edema</td></tr><tr><td>Solantin</td><td>Thromboembolism</td><td>Dizziness, abdomen distress, angina, headache</td></tr><tr><td>Ursodeoxycholic acid</td><td>Liver cirrhosis</td><td>Gastrointestinal disturbance</td></tr><tr><td>Atorvastatin</td><td>Hyperlipidemia</td><td>Gastrointestinal disturbance, elevated liver enzyme, myopathy, neuropathy</td></tr><tr><td>Chinese herb drugs</td><td>Multiple somatic complaints</td><td>Unknown</td></tr></table>
c0c77c130ef6f925de877e0e4c29e533540c5c09c672ba57caad2276ad845d81.png
complex
<table><tr><td></td><td></td><td colspan="3">males</td><td colspan="3">females</td></tr><tr><td>DEPCAT</td><td>Region</td><td>1980&#8211;82</td><td>1990&#8211;92</td><td>2000&#8211;02</td><td>1980&#8211;82</td><td>1990&#8211;92</td><td>2000&#8211;02</td></tr><tr><td></td><td>H&amp;I</td><td>342</td><td>315</td><td>244</td><td>114</td><td>172</td><td>132</td></tr><tr><td></td><td>NE</td><td>290</td><td>217</td><td>170</td><td>170</td><td>177</td><td>135</td></tr><tr><td></td><td>Clyde</td><td>330</td><td>221</td><td>161</td><td>201</td><td>135</td><td>119</td></tr><tr><td>1</td><td>Central</td><td>304</td><td>309</td><td>125</td><td>150</td><td>111</td><td>90</td></tr><tr><td></td><td>East</td><td>318</td><td>238</td><td>199</td><td>162</td><td>146</td><td>140</td></tr><tr><td></td><td>SW</td><td>349</td><td>198</td><td>140</td><td>210</td><td>76</td><td>111</td></tr><tr><td></td><td>SE</td><td>296</td><td>225</td><td>132</td><td>187</td><td>145</td><td>119</td></tr><tr><td></td><td>H&amp;I</td><td>425</td><td>276</td><td>221</td><td>249</td><td>171</td><td>145</td></tr><tr><td></td><td>NE</td><td>367</td><td>247</td><td>218</td><td>217</td><td>160</td><td>132</td></tr><tr><td></td><td>Clyde</td><td>386</td><td>287</td><td>215</td><td>229</td><td>204</td><td>140</td></tr><tr><td>2</td><td>Central</td><td>377</td><td>288</td><td>202</td><td>226</td><td>220</td><td>138</td></tr><tr><td></td><td>East</td><td>366</td><td>289</td><td>204</td><td>202</td><td>195</td><td>135</td></tr><tr><td></td><td>SW</td><td>420</td><td>257</td><td>240</td><td>221</td><td>194</td><td>139</td></tr><tr><td></td><td>SE</td><td>365</td><td>282</td><td>190</td><td>239</td><td>155</td><td>116</td></tr><tr><td></td><td>H&amp;I</td><td>445</td><td>334</td><td>290</td><td>265</td><td>190</td><td>169</td></tr><tr><td></td><td>NE</td><td>406</td><td>299</td><td>272</td><td>254</td><td>171</td><td>154</td></tr><tr><td></td><td>Clyde</td><td>454</td><td>374</td><td>281</td><td>277</td><td>196</td><td>168</td></tr><tr><td>3</td><td>Central</td><td>439</td><td>436</td><td>265</td><td>295</td><td>196</td><td>168</td></tr><tr><td></td><td>East</td><td>422</td><td>326</td><td>259</td><td>257</td><td>197</td><td>150</td></tr><tr><td></td><td>SW</td><td>479</td><td>327</td><td>254</td><td>265</td><td>197</td><td>155</td></tr><tr><td></td><td>SE</td><td>426</td><td>288</td><td>289</td><td>232</td><td>171</td><td>161</td></tr><tr><td></td><td>H&amp;I</td><td>564</td><td>403</td><td>334</td><td>281</td><td>199</td><td>200</td></tr><tr><td></td><td>NE</td><td>446</td><td>370</td><td>371</td><td>248</td><td>223</td><td>179</td></tr><tr><td></td><td>Clyde</td><td>534</td><td>449</td><td>352</td><td>297</td><td>222</td><td>196</td></tr><tr><td>4</td><td>Central</td><td>491</td><td>329</td><td>341</td><td>321</td><td>215</td><td>202</td></tr><tr><td></td><td>East</td><td>462</td><td>361</td><td>304</td><td>272</td><td>232</td><td>176</td></tr><tr><td></td><td>SW</td><td>472</td><td>344</td><td>302</td><td>297</td><td>251</td><td>190</td></tr><tr><td></td><td>SE</td><td>447</td><td>407</td><td>329</td><td>267</td><td>222</td><td>197</td></tr><tr><td></td><td>H&amp;I</td><td>661</td><td>521</td><td>390</td><td>192</td><td>312</td><td>186</td></tr><tr><td></td><td>NE</td><td>592</td><td>416</td><td>497</td><td>324</td><td>262</td><td>242</td></tr><tr><td></td><td>Clyde</td><td>565</td><td>446</td><td>445</td><td>315</td><td>252</td><td>230</td></tr><tr><td>5</td><td>Central</td><td>511</td><td>416</td><td>412</td><td>298</td><td>228</td><td>226</td></tr><tr><td></td><td>East</td><td>489</td><td>430</td><td>386</td><td>338</td><td>238</td><td>206</td></tr><tr><td></td><td>SW</td><td>554</td><td>428</td><td>375</td><td>323</td><td>272</td><td>234</td></tr><tr><td></td><td>SE</td><td>513</td><td>462</td><td>410</td><td>287</td><td>258</td><td>224</td></tr><tr><td></td><td>H&amp;I</td><td>913</td><td>452</td><td>846</td><td>350</td><td>100</td><td>88</td></tr><tr><td></td><td>NE</td><td>392</td><td>435</td><td>583</td><td>277</td><td>249</td><td>260</td></tr><tr><td></td><td>Clyde</td><td>646</td><td>518</td><td>515</td><td>368</td><td>293</td><td>255</td></tr><tr><td>6</td><td>Central</td><td>628</td><td>782</td><td>388</td><td>318</td><td>338</td><td>261</td></tr><tr><td></td><td>East</td><td>506</td><td>466</td><td>445</td><td>369</td><td>291</td><td>249</td></tr><tr><td></td><td>SW</td><td>591</td><td>488</td><td>425</td><td>351</td><td>276</td><td>262</td></tr><tr><td></td><td>SE</td><td>561</td><td>411</td><td>403</td><td>300</td><td>302</td><td>220</td></tr><tr><td></td><td>H&amp;I</td><td>607</td><td>0</td><td></td><td>0</td><td>0</td><td></td></tr><tr><td></td><td>NE</td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Clyde</td><td>735</td><td>635</td><td>717</td><td>403</td><td>382</td><td>340</td></tr><tr><td>7</td><td>Central</td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>East</td><td>557</td><td>2547</td><td>623</td><td>303</td><td>0</td><td>307</td></tr><tr><td></td><td>SW</td><td>794</td><td>544</td><td></td><td>206</td><td>268</td><td></td></tr><tr><td></td><td>SE</td><td>697</td><td>666</td><td>675</td><td>380</td><td>397</td><td>455</td></tr></table>
2148b1a4a33bbfa08c46c92e6240c046357a8d2a436748e85107c6028d11fc63.png
complex
<table><tr><td>Gene</td><td>Exon/intron</td><td>Nucleotide change</td><td>Aminoacid change</td><td>LCn = 175OR (95% CI)</td><td>MPT-LCn = 115OR (95% CI)</td><td>MPTn = 68OR (95% CI)</td><td>Controlsn = 506</td></tr><tr><td rowspan="2"><i>RAD50</i></td><td rowspan="2">Ex. 4</td><td rowspan="2">c.379G&gt;A</td><td rowspan="2">p.V127I</td><td>2</td><td rowspan="2">-</td><td rowspan="2">-</td><td rowspan="2">2</td></tr><tr><td>2.91 (0.41-20.85)</td></tr><tr><td rowspan="2"> </td><td rowspan="2">Ex. 7</td><td rowspan="2">c.943G&gt;T</td><td rowspan="2">p.V315L</td><td rowspan="2">-</td><td>2</td><td rowspan="2">-</td><td rowspan="2">1</td></tr><tr><td>8.96 (0.81-99.68)</td></tr><tr><td rowspan="2"> </td><td rowspan="2">Ex. 25</td><td rowspan="2">c.3876C&gt;T</td><td rowspan="2">-</td><td>1</td><td rowspan="2">-</td><td rowspan="2">-</td><td rowspan="2">0/180</td></tr><tr><td>8.71 (0.35-215)</td></tr><tr><td><i>MRE11</i></td><td>Int. 16</td><td>c.1783-86delAG</td><td>-</td><td>39</td><td>18</td><td>20</td><td>61/279</td></tr><tr><td> </td><td> </td><td> </td><td> </td><td>1.03 (0.65-1.62)</td><td>0.66 (0.37-1.18)</td><td>1.49 (0.82-2.69)</td><td> </td></tr></table>
2ee2e52a7b7322e07334484ecd6e6edc8bbe3fb4525abd48d1512b2c41639eb8.png
complex
<table><tr><td>Patient study code</td><td>Pre-study dopamine agonist</td><td>Trial arm</td><td>First IMP</td><td>Daily dose (mg)</td><td>Number of days on IMP</td><td>Second IMP</td><td>Daily dose (mg)</td><td>Number of days on IMP</td></tr><tr><td>PD1</td><td>RPR</td><td>1</td><td>PPX</td><td>2.1</td><td>3</td><td>RPR<sup>a, b</sup></td><td>8</td><td>134</td></tr><tr><td>PD2</td><td>RPR</td><td>1</td><td>PPX</td><td>2.62</td><td>58</td><td>RPR</td><td>10</td><td>48</td></tr><tr><td>PD3</td><td>RPR</td><td>2</td><td>RPR</td><td>6</td><td>51</td><td>PPX</td><td>1.57</td><td>58</td></tr><tr><td>PD4</td><td>RPR</td><td>2</td><td>RPR</td><td>4</td><td>40</td><td>PPX</td><td>1.05</td><td>55</td></tr><tr><td>PD5</td><td colspan="8">Consented but then withdrew before taking first IMP</td></tr><tr><td>PD6</td><td>PPX</td><td>1</td><td>PPX</td><td>2.1</td><td>64</td><td>RPR</td><td>8</td><td>52</td></tr><tr><td>PD7</td><td>PPX</td><td>2</td><td>RPR</td><td>10</td><td>13</td><td>PPX<sup>a, b</sup></td><td>2.62</td><td>97</td></tr><tr><td>PD8</td><td>RPR</td><td>2</td><td>RPR</td><td>12</td><td>54</td><td>PPX</td><td>3.15</td><td>62</td></tr><tr><td>PD9</td><td>PPX</td><td>1</td><td>PPX</td><td>1.57</td><td>62</td><td>RPR</td><td>6</td><td>56</td></tr><tr><td>PD10</td><td>RPR</td><td>1</td><td>PPX</td><td>2.1</td><td>53</td><td>RPR</td><td>8</td><td>68</td></tr><tr><td>PD11</td><td>PPX</td><td>1</td><td>PPX</td><td>1.05</td><td>48</td><td>RPR<sup>b</sup></td><td>4</td><td>30</td></tr><tr><td>PD12</td><td>PPX</td><td>2</td><td>RPR</td><td>10</td><td>52</td><td>PPX</td><td>2.62</td><td>56</td></tr><tr><td>PD13</td><td colspan="8">Consented but then withdrew before taking first IMP</td></tr><tr><td>PD14</td><td>PPX</td><td>1</td><td>PPX</td><td>0.52</td><td>52</td><td>RPR</td><td>2</td><td>37</td></tr><tr><td>PD15</td><td colspan="8">Consented but then withdrew before taking first IMP</td></tr><tr><td>PD16</td><td>PPX</td><td>1</td><td>PPX</td><td>1.57</td><td>63</td><td>RPR</td><td>6</td><td>55</td></tr><tr><td>PD17</td><td>PPX</td><td>2</td><td>RPR</td><td>6</td><td>60</td><td>PPX</td><td>1.57</td><td>37</td></tr><tr><td>PD18</td><td>PPX</td><td>2</td><td>RPR</td><td>6</td><td>3</td><td colspan="3">Withdrew from IMP and study</td></tr><tr><td>PD19</td><td>RPR</td><td>1</td><td>PPX</td><td>2.1</td><td>55</td><td>RPR</td><td>8</td><td>84</td></tr><tr><td>PD20</td><td>PPX</td><td>2</td><td>RPR</td><td>8</td><td>66</td><td>PPX</td><td>2.1</td><td>41</td></tr><tr><td>PD21</td><td>PPX</td><td>1</td><td>PPX</td><td>3.15</td><td>100</td><td>RPR<sup>b</sup></td><td>12</td><td>7</td></tr><tr><td>PD22</td><td>RPR</td><td>2</td><td>RPR</td><td>6</td><td>55</td><td>PPX</td><td>1.57</td><td>48</td></tr><tr><td>PD23</td><td>PPX</td><td>2</td><td>RPR</td><td>8</td><td>5</td><td colspan="3">Withdrew from IMP and study</td></tr><tr><td>PD24</td><td>RPR</td><td>2</td><td>RPR</td><td>6</td><td>58</td><td>PPX</td><td>1.57</td><td>37</td></tr><tr><td>PD25</td><td>RPR</td><td>2</td><td>RPR</td><td>2</td><td>68</td><td>PPX</td><td>0.52</td><td>62</td></tr></table>
8add28819c8e36000d8c4e445bcf8f47a6a39de0ffbb40520b3a218903b889a7.png
simple
<table><tr><td>Parental feeding practices</td><td>Family breakfast frequency</td><td>Family dinner frequency</td><td>Family supper frequency</td></tr><tr><td>Monitoring</td><td>.11*</td><td>.04</td><td>.02</td></tr><tr><td>Child control</td><td>-.09**</td><td>-.11*</td><td>-.03</td></tr><tr><td>Encourage balance and variety</td><td>.06</td><td>.08**</td><td>.04</td></tr><tr><td>Environment</td><td>.13*</td><td>.09**</td><td>.12*</td></tr><tr><td>Involvement</td><td>.01</td><td>-.00</td><td>.02</td></tr><tr><td>Pressure to eat</td><td>.08**</td><td>.00</td><td>.01</td></tr><tr><td>Restriction for weight</td><td>-.01</td><td>-.04</td><td>-.02</td></tr><tr><td>Food as reward</td><td>-.02</td><td>-.09**</td><td>-.00</td></tr><tr><td>Restriction for health</td><td>-.05</td><td>-.06</td><td>-.05</td></tr><tr><td>Teaching nutrition</td><td>.10*</td><td>.06</td><td>.09**</td></tr><tr><td>Modeling</td><td>.11*</td><td>.06</td><td>.08**</td></tr><tr><td>Emotion regulation</td><td>-.02</td><td>-.08**</td><td>.01</td></tr></table>
1b024bb8aaede6c59c162a177c084ade1a1ba2f41730ff54f420105bda50857d.png
simple
<table><tr><td>Variables</td><td>T1D (<i>n</i> = 19)</td><td>T2D (<i>n</i> = 21)</td><td><i>P</i> value</td></tr><tr><td>Female/male (<i>n</i>/<i>n</i>)</td><td>13/6</td><td>9/12</td><td>0.105</td></tr><tr><td>Age (years)</td><td>35 &#177; 19</td><td>52 &#177; 10</td><td>0.001</td></tr><tr><td>Duration of diabetes (years)</td><td>7.00 (0.00&#8211;26.00)</td><td>5.00 (0.00&#8211;15.00)</td><td>0.455</td></tr><tr><td>Plasma glucose (mmol/L)</td><td>31.82 &#177; 8.53</td><td>26.37 &#177; 6.81</td><td>0.035</td></tr><tr><td>HbA1c (%)</td><td>12.97 &#177; 2.25</td><td>12.07 &#177; 1.73</td><td>0.214</td></tr><tr><td>Arterial pH</td><td>7.01 &#177; 0.16</td><td>7.04 &#177; 0.14</td><td>0.486</td></tr><tr><td>HCO<sub>3</sub> (mmol/L)</td><td>4.71 &#177; 3.50</td><td>5.54 &#177; 3.48</td><td>0.420</td></tr><tr><td>Alanine aminotransferase (U/L)</td><td>15.57 &#177; 5.79</td><td>15.92 &#177; 6.22</td><td>0.880</td></tr><tr><td>Aspartate aminotransferase (U/L)</td><td>19.21 &#177; 13.46</td><td>18.08 &#177; 5.98</td><td>0.782</td></tr><tr><td><i>&#947;</i>-glutamyl transpeptidase (U/L)</td><td>17.31 &#177; 7.20</td><td>18.62 &#177; 6.99</td><td>0.643</td></tr><tr><td>Total bilirubin (<i>&#956;</i>mol/L)</td><td>11.42 &#177; 4.38</td><td>11.06 &#177; 4.71</td><td>0.843</td></tr><tr><td>Direct bilirubin (<i>&#956;</i>mol/L)</td><td>4.42 &#177; 1.27</td><td>4.78 &#177; 1.97</td><td>0.597</td></tr><tr><td>Total protein (g/L)</td><td>58.48 &#177; 11.60</td><td>60.32 &#177; 7.10</td><td>0.632</td></tr><tr><td>Albumin (g/L)</td><td>36.66 &#177; 4.76</td><td>35.42 &#177; 5.55</td><td>0.463</td></tr><tr><td>Globulin (g/L)</td><td>21.85 &#177; 6.94</td><td>26.48 &#177; 4.90</td><td>0.061</td></tr><tr><td>Prealbumin (mg/dL)</td><td>135.40 &#177; 52.78</td><td>130.53 &#177; 53.91</td><td>0.775</td></tr><tr><td>Serum creatinine (<i>&#956;</i>mol/L)</td><td>99.06 &#177; 53.62</td><td>119.32 &#177; 90.06</td><td>0.399</td></tr><tr><td>eGFR (mL/min per 1.73 m<sup>2</sup>)</td><td>62.90 &#177; 25.03</td><td>57.19 &#177; 26.58</td><td>0.490</td></tr><tr><td>Uric acid (<i>&#956;</i>mol/L)</td><td>458.53 &#177; 128.66</td><td>476.58 &#177; 157.40</td><td>0.746</td></tr></table>
69317b472c0105756707b5c385614d5eab001a768d379f68827688ade3a0be5b.png
complex
<table><tr><td rowspan="2">Target gene symbol</td><td rowspan="2">miRNAs</td><td>Non-tumor</td><td>Tumor</td><td rowspan="2">Adjusted <i>P</i> value *</td><td rowspan="2">Regulation in HCC tumor</td></tr><tr><td>Mean (Log2), SD</td><td>Mean (Log2), SD</td></tr><tr><td><i>GRASP</i></td><td>hsa-miR-320b</td><td>&#8722;8.97, 0.75</td><td>&#8722;10.10, 0.96</td><td>8.95E-03</td><td>Down</td></tr><tr><td><i>TSPYL5</i></td><td>hsa-miR-193a-3p</td><td>&#8722;8.21, 1.06</td><td>&#8722;9.53, 0.88</td><td>7.58E-03</td><td>Down</td></tr><tr><td></td><td>hsa-let-7g</td><td>&#8722;3.43, 0.67</td><td>&#8722;4.11, 0.55</td><td>2.32E-02</td><td>Down</td></tr><tr><td></td><td>hsa-let-7a</td><td>&#8722;6.43, 0.64</td><td>&#8722;7.35, 0.86</td><td>1.42E-02</td><td>Down</td></tr><tr><td></td><td>hsa-let-7e</td><td>&#8722;4.05, 0.82</td><td>&#8722;4.78, 0.63</td><td>3.86E-02</td><td>Down</td></tr><tr><td></td><td>hsa-let-7c</td><td>&#8722;6.88, 0.50</td><td>&#8722;8.62, 1.08</td><td>2.24E-04</td><td>Down</td></tr><tr><td></td><td>hsa-let-7b</td><td>&#8722;4.53, 0.86</td><td>&#8722;5.89, 1.18</td><td>8.94E-03</td><td>Down</td></tr><tr><td></td><td>hsa-miR-320b</td><td>&#8722;8.97, 0.75</td><td>&#8722;10.10, 0.96</td><td>8.95E-03</td><td>Down</td></tr><tr><td></td><td>hsa-miR-27b</td><td>&#8722;5.69, 0.79</td><td>&#8722;6.48, 0.70</td><td>2.84E-02</td><td>Down</td></tr></table>
c4e789be15484471a48bf32454dc7067158ff83e226d4ef9b14d27f33fe6a08b.png
complex
<table><tr><td>Diagnoses</td><td>Patient count</td><td>% of Total</td></tr><tr><td colspan="2">Pre-Index Period</td><td> </td></tr><tr><td>Total Unique Patients in the Population</td><td>5,490</td><td> </td></tr><tr><td>Patients with &#8805; 1 Pertussis-like event</td><td>3,140</td><td>57</td></tr><tr><td>Acute Respiratory:</td><td>2,857</td><td>52</td></tr><tr><td> COUGH</td><td>1,350</td><td>25</td></tr><tr><td> UPPER RESPIRATORY TRACT INFECTION</td><td>1,004</td><td>18</td></tr><tr><td> ACUTE BRONCHITIS</td><td>938</td><td>17</td></tr><tr><td> ASTHMA</td><td>449</td><td>8</td></tr><tr><td> ALLERGY</td><td>413</td><td>8</td></tr><tr><td> LOWER RESPIRATORY TRACT INFECTION</td><td>387</td><td>7</td></tr><tr><td> OTHER PNEUMONIA</td><td>313</td><td>6</td></tr><tr><td>Other :</td><td>1,798</td><td>33</td></tr><tr><td> HYPERTENSION</td><td>579</td><td>11</td></tr><tr><td> SHORTNESS OF BREATH</td><td>368</td><td>7</td></tr><tr><td> HIGH CHOLESTEROL</td><td>316</td><td>6</td></tr><tr><td> GERD</td><td>290</td><td>5</td></tr><tr><td> CHEST PAIN</td><td>266</td><td>5</td></tr><tr><td> COPD AND OTHER ALLIED CONDITIONS</td><td>229</td><td>4</td></tr><tr><td> DIABETES</td><td>224</td><td>4</td></tr><tr><td> LUMBAR STRAIN OR BACK PAIN</td><td>171</td><td>3</td></tr><tr><td colspan="2">Post-Index Period</td><td> </td></tr><tr><td>Total Unique Patients in the Population</td><td>5,490</td><td>100</td></tr><tr><td>Acute Respiratory:</td><td>5,053</td><td>92</td></tr><tr><td> WHOOPING COUGH-UNSPECIFIED ORGANISM</td><td>2,224</td><td>41</td></tr><tr><td> COUGH</td><td>2,222</td><td>40</td></tr><tr><td> UPPER RESPIRATORY TRACT INFECTION</td><td>770</td><td>14</td></tr><tr><td> ACUTE BRONCHITIS</td><td>694</td><td>13</td></tr><tr><td> WHOOPING COUGH-BORDETELLA PERTUSSIS</td><td>605</td><td>11</td></tr><tr><td> ASTHMA</td><td>551</td><td>10</td></tr><tr><td> OTHER PNEUMONIA</td><td>468</td><td>9</td></tr><tr><td> ALLERGY</td><td>404</td><td>7</td></tr><tr><td> LOWER RESPIRATORY TRACT INFECTION</td><td>359</td><td>7</td></tr><tr><td> PNEUMONIA IN WHOOPING COUGH</td><td>237</td><td>4</td></tr><tr><td>Other:</td><td>2,309</td><td>42</td></tr><tr><td> HYPERTENSION</td><td>851</td><td>16</td></tr><tr><td> HIGH CHOLESTEROL</td><td>495</td><td>9</td></tr><tr><td> SHORTNESS OF BREATH</td><td>445</td><td>8</td></tr><tr><td> DIABETES</td><td>421</td><td>8</td></tr><tr><td> GERD</td><td>421</td><td>8</td></tr><tr><td> COPD AND OTHER ALLIED CONDITIONS</td><td>388</td><td>7</td></tr><tr><td> CHEST PAIN</td><td>300</td><td>5</td></tr></table>
1a38828f6b78a815c87ccf6f6a2d4c6445f88d6c4ddad63442edfcdd0754dfeb.png
simple
<table><tr><td>Item</td><td>Experiment A [8]</td><td>Experiment B</td></tr><tr><td>Study design</td><td>Design: parallel crossover Diets: control (CON) and treatment (TRMT)Duration: 22 d with glucose kinetics assessed on day 19 of study </td><td>Design: parallel crossoverDiets: control (CON) and treatment (TRMT)Duration: 63 d with glucose kinetics assessed on day 35 of study</td></tr><tr><td>Study population</td><td>A total of 6 neutered male Labrador Retrievers, 3-black-coated (3.9 yr; 27.3 kg) and 3-chocolate-coated (6.8 yr; 35.0 kg)</td><td>A total of 12 black Labrador Retrievers, 5 spayed females and 7 neutered males (27.0 &#177; 0.6 kg; 4.9 &#177; 0.2 yr of age)</td></tr><tr><td>Key details of glucose kinetics experiment</td><td>Isotope: U-<sup>13</sup>C-glucosePrime: 77.8 <i>&#956;</i>mol/kgConstant: 0.136 <i>&#956;</i>mol/min&#183;kgFasting collections (18 h since last meal): 6 blood samples were taken at 60, 85, 110, 135, 160, and 185 min followed by 4 breath samples taken at 220, 245, 270, and 295 min after isotope infusion (start of isotope infused considered time 0) Postprandial collections: total food ration of 14 g/kg divided into 15 equal sized meals fed in 25 min intervals; 6 blood samples were taken at 60, 85, 110, 135, 160, and 185 min followed by 4 breath samples taken at 220, 245, 270, 295, 320, and 345 min after initial meal</td><td>Isotope: U-<sup>13</sup>C-glucosePrime: 8.1 <i>&#956;</i>mol/kgConstant: 0.136 <i>&#956;</i>mol/min&#183;kgFasting collections (18 h since last meal): 6 fasting blood samples were taken at 90, 105, 120, 135, 150, and 165 min followed by 6 breath samples taken at 180, 205, 230, 255, 280, and 305 min after isotope infusion (start of isotope infused considered time 0)Postprandial collections: total food ration of 23 g/kg divided into 14 equal sized meals fed in 25 min intervals; 6 fasting blood samples were taken at 90, 105, 120, 135, 150, and 165 min followed by 6 breath samples taken at 180, 205, 230, 255, 280, and 305 min after initial meal.</td></tr></table>
ed60b4bc9dfc32da2ea951a17e1c9feaff727c3a5a028d8355e60ba80f7d4260.png
complex
<table><tr><td rowspan="3">Cutoff OD</td><td colspan="4">Model using<sup><i>a</i></sup>:</td><td rowspan="3">Overall accuracy (%)<sup><i>b</i></sup></td></tr><tr><td colspan="2">On-admission sample alone</td><td colspan="2">Paired samples</td></tr><tr><td>Sensitivity</td><td>Specificity</td><td>Sensitivity</td><td>Specificity</td></tr><tr><td>1.010</td><td>78.6 (68.8&#8211;85.2)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>93.5 (92.5&#8211;96.2)</td><td>93.3</td></tr><tr><td>1.023</td><td>73.3 (64.7&#8211;81.5)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>93.5 (92.5&#8211;96.2)</td><td>93.0</td></tr><tr><td>1.080</td><td>73.3 (64.7&#8211;81.5)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>94.4 (93.5&#8211;97.1)</td><td>93.3</td></tr><tr><td>1.093</td><td>70.0 (61.3&#8211;77.8)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>94.4 (93.5&#8211;97.1)</td><td>93.0</td></tr><tr><td>1.165</td><td>70.0 (61.3&#8211;77.8)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>95.3 (94.4&#8211;98.1)</td><td>93.3</td></tr><tr><td>1.214</td><td>70.0 (61.3&#8211;77.8)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>95.3 (94.4&#8211;98.1)</td><td>93.3</td></tr><tr><td>1.273</td><td>70.0 (61.3&#8211;77.8)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>96.3 (95.3&#8211;99.0)</td><td>93.7</td></tr><tr><td>1.275</td><td>70.0 (61.3&#8211;77.8)</td><td>100 (98.2&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>96.3 (95.3&#8211;99.0)</td><td>93.7</td></tr><tr><td>1.307</td><td>69.0 (60.6&#8211;76.9)</td><td>100 (99.1&#8211;100)</td><td>85.2 (77.4&#8211;87.1)</td><td>97.2 (96.3&#8211;100)</td><td>94.1</td></tr><tr><td>1.474</td><td>69.0 (60.6&#8211;76.9)</td><td>100 (99.1&#8211;100)</td><td>85.7 (77.4&#8211;86.7)</td><td>98.1 (97.2&#8211;100)</td><td>94.4</td></tr></table>
c8e2a46c20f1a200601dfb6bbe8fc899d52bb4b89d07893e3fa3998decc77eb8.png
simple
<table><tr><td>PCC</td><td></td><td>Total</td><td>TR</td><td>TS</td></tr><tr><td></td><td></td><td>S</td><td>NS</td><td>S</td><td>NS</td><td>S</td><td>NS</td></tr><tr><td></td><td>MACCS</td><td>154</td><td>1050</td><td>126</td><td>838</td><td>28</td><td>212</td></tr><tr><td>0.25</td><td>Descriptors</td><td>154</td><td>1050</td><td>123</td><td>841</td><td>31</td><td>209</td></tr><tr><td></td><td>Random</td><td>154</td><td>1050</td><td>123</td><td>840</td><td>31</td><td>210</td></tr><tr><td></td><td>MACCS</td><td>98</td><td>1106</td><td>85</td><td>879</td><td>13</td><td>227</td></tr><tr><td>0.30</td><td>Descriptors</td><td>98</td><td>1106</td><td>80</td><td>884</td><td>18</td><td>222</td></tr><tr><td></td><td>Random</td><td>98</td><td>1106</td><td>78</td><td>962</td><td>20</td><td>222</td></tr></table>
5c74cef55f8e20b738d2d385c1c69d72266718967810776365a50cd8e23ab530.png
simple
<table><tr><td></td><td>BMI &lt;25 kg/m<sup>2</sup> (n=1296)</td><td>BMI &#8805;25 kg/m<sup>2</sup> (n=3382)</td><td><i>P</i>-value</td></tr><tr><td>Use of allopirunol, n</td><td>379(29.2)</td><td>2031(60.1)</td><td>&lt;0.05</td></tr><tr><td>Use of febuxostat, n</td><td>82(6.3)</td><td>189(5.6)</td><td>&gt;0.05</td></tr><tr><td>Use of benzbromarone, n</td><td>367(28.3)</td><td>228(6.7)</td><td>&lt;0.05</td></tr><tr><td>Use of combination urate-lowering therapies, n</td><td>35(2.7)</td><td>577(17.1)</td><td>&lt;0.05</td></tr><tr><td>Lifestyle intervention only, n</td><td>433(33.4)</td><td>357(10.6)</td><td>&lt;0.05</td></tr></table>
b5e907236bb01f6433b9bf61a07b45e85d5d154358424fecdc752a33518390d6.png
simple
<table><tr><td>Parameters</td><td>N = 506</td></tr><tr><td>Age in years, mean (SD)</td><td>23.8 (3.4)</td></tr><tr><td>Age categories</td><td> </td></tr><tr><td>&lt;20 yr, n (%)</td><td>10 (1.9)</td></tr><tr><td>20-29 yr, n (%)</td><td>454 (89.9)</td></tr><tr><td>&#8805;30 yr, n (%)</td><td>41 (8.1)</td></tr><tr><td>Residence</td><td> </td></tr><tr><td>Urban, n (%)</td><td>148 (29.2)</td></tr><tr><td>Rural, n (%)</td><td>359 (70.8)</td></tr><tr><td>Education</td><td> </td></tr><tr><td>No schooling, n (%)</td><td>161 (31.8)</td></tr><tr><td>Primary, n (%)</td><td>136 (26.8)</td></tr><tr><td>Secondary, n (%)</td><td>173 (34.2)</td></tr><tr><td>Higher, n (%)</td><td>36 (7.1)</td></tr><tr><td>SES<sup>1 </sup>rank (quintiles) n (%)</td><td> </td></tr><tr><td>1 &#8211; Poorest</td><td>117 (23.1)</td></tr><tr><td>2</td><td>107 (21.2)</td></tr><tr><td>3</td><td>112 (22.1)</td></tr><tr><td>4</td><td>85 (16.8)</td></tr><tr><td>5</td><td>85 (16.8)</td></tr><tr><td>Gravidity</td><td> </td></tr><tr><td>Primigravidae, n (%)</td><td>216 (42.7)</td></tr><tr><td>Secundigravidae, n (%)</td><td>162 (32.0)</td></tr><tr><td>Gravidae-3, n (%)</td><td>73 (14.4)</td></tr><tr><td>Gravidae-4, n (%)</td><td>34 (6.7)</td></tr><tr><td>Multigravidae (&#8805;5)<sup>2</sup> n (%)</td><td>21 (4.2)</td></tr><tr><td>Used bednet previous night, n (%)</td><td>89 (17.8)</td></tr><tr><td>ITN (any), n (%)</td><td>1 (0.2)</td></tr><tr><td>Used any drug to prevent malaria, n (%)</td><td>4 (0.8)</td></tr><tr><td>Reported using haematinics, n (%)</td><td>427 (84.7)</td></tr><tr><td>Morbidity and Outcomes</td><td> </td></tr><tr><td>Reported fever previous week, n (%)</td><td>82 (16.2)</td></tr><tr><td>Used antimalarial for fever, n (%)</td><td>10 (1.9)</td></tr><tr><td>Maternal fever at delivery<sup>3</sup>, n (%)</td><td>35 (6.9)</td></tr><tr><td>Birth weight<sup>&#177;</sup> (g), mean (SD)</td><td>2621 (450)</td></tr><tr><td>Birth weight &lt;2500 g, n (%)</td><td>176 (37.1)</td></tr><tr><td>Baby&#8217;s gestational age in weeks<sup>4</sup>, mean, (SD)</td><td>37.2 (1.3)</td></tr><tr><td>Preterm babies &lt;37 weeks), n (%)</td><td>95 (20.0)</td></tr><tr><td>Stillbirths<sup>=&#824;</sup>, n (%)</td><td>22 (4.4)</td></tr><tr><td>Stillbirths in uninfected women, n (%)</td><td>18 (3.6)</td></tr><tr><td>Maternal Hb (g/dL), mean (SD)</td><td>10.5 (2.2)</td></tr></table>
4e7aa033e6e7a9268117e7894d900c4d5140ee870dab203cc9be1ba3c4271c8c.png
simple
<table><tr><td>Toxicity</td><td>Overall incidence, no. (%)</td><td>Grade 1 and 2, no. (%)</td><td>Grade 3 and 4, no. (%)</td></tr><tr><td>Hyperglycemia</td><td>19 (79)</td><td>19 (79)</td><td></td></tr><tr><td>Fatigue</td><td>19 (79)</td><td>18 (75)</td><td>1 (4)</td></tr><tr><td>Thrombocytopenia</td><td>12 (50)</td><td>12 (50)</td><td></td></tr><tr><td>Headache</td><td>11 (46)</td><td>10 (43)</td><td>1 (4)</td></tr><tr><td>Nausea</td><td>10 (42)</td><td>9 (38)</td><td>1 (4)</td></tr><tr><td>Leukopenia</td><td>9 (38)</td><td>9 (38)</td><td></td></tr><tr><td>ALT elevations</td><td>8 (33)</td><td>8 (33)</td><td></td></tr><tr><td>AST elevations</td><td>7 (29)</td><td>7 (29)</td><td></td></tr><tr><td>Bilirubin elevations</td><td>5 (21)</td><td>5 (21)</td><td></td></tr><tr><td>Neutropenia</td><td>5 (21)</td><td>5 (21)</td><td></td></tr><tr><td>Anemia</td><td>5 (21)</td><td>4 (17)</td><td>1 (4)</td></tr><tr><td>Seizures</td><td>5 (21)</td><td>4 (17)</td><td>1 (4)</td></tr><tr><td>Vomiting</td><td>5 (21)</td><td>4 (17)</td><td>1 (4)</td></tr><tr><td>Thyroid toxicity</td><td>4 (17)</td><td>4 (17)</td><td></td></tr><tr><td>Diarrhea</td><td>4 (17)</td><td>4 (17)</td><td></td></tr><tr><td>Myalgias/Arthralgias</td><td>3 (13)</td><td>3 (13)</td><td></td></tr><tr><td>Rash</td><td>2 (8)</td><td>2 (8)</td><td></td></tr><tr><td>Pyrexia</td><td>2 (8)</td><td>2 (8)</td><td></td></tr><tr><td>Lipase</td><td>1 (4)</td><td>1 (4)</td><td></td></tr><tr><td>Amylase</td><td>1 (4)</td><td>1 (4)</td><td></td></tr><tr><td>Mucositis</td><td>1 (4)</td><td>1 (4)</td><td></td></tr></table>
a8242e847963d849e08323d5ef542df9254463402b855e0b1a3c7fe4a4803a64.png
complex
<table><tr><td>Characteristics</td><td>Category</td><td>Male N (%)</td><td>Female N (%)</td><td>Total N (%)</td></tr><tr><td rowspan="3">Age (years)</td><td>&lt;10</td><td>12 (46.2)</td><td>56 (14.0)</td><td>68 (16.0)</td></tr><tr><td>11&#8211;14</td><td>10 (38.5)</td><td>178 (44.5)</td><td>188 (44.1)</td></tr><tr><td>&gt;14</td><td>4 (15.4)</td><td>166 (41.5)</td><td>170 (39.9)</td></tr><tr><td rowspan="3">Education</td><td>Preschool</td><td>4 (15.4)</td><td>22 (5.5)</td><td>26 (6.1)</td></tr><tr><td>Pupil</td><td>19 (73.1)</td><td>224 (56.0)</td><td>243 (57.0)</td></tr><tr><td>Other</td><td>3 (11.5)</td><td>154 (38.5)</td><td>157 (36.9)</td></tr><tr><td rowspan="8">Perpetrator</td><td>Father</td><td>1 (3.8)</td><td>12 (3.0)</td><td>13 (3.1)</td></tr><tr><td>Stepfather</td><td>0</td><td>24 (6.0)</td><td>24 (5.6)</td></tr><tr><td>Stepbrother</td><td>3 (11.5)</td><td>2 (0.5)</td><td>5 (1.2)</td></tr><tr><td>Cousin</td><td>3 (11.5)</td><td>2 (0.5)</td><td>5 (1.2)</td></tr><tr><td>Grandfather</td><td>1 (3.8)</td><td>0</td><td>1 (0.2)</td></tr><tr><td>Other relative</td><td>0</td><td>31 (7.8)</td><td>31 (7.3)</td></tr><tr><td>Familiar</td><td>10 (38.5)</td><td>189 (47.3)</td><td>199 (46.7)</td></tr><tr><td>Stranger</td><td>8 (30.8)</td><td>140 (35.0)</td><td>148 (34.7)</td></tr><tr><td rowspan="7">Escorter</td><td>Alone</td><td>0</td><td>43 (10.8)</td><td>43 (10.1)</td></tr><tr><td>Mother</td><td>9 (34.6)</td><td>96 (24.0)</td><td>105 (24.6)</td></tr><tr><td>Parents</td><td>6 (23.1)</td><td>21 (5.3)</td><td>27 (6.3)</td></tr><tr><td>Other relative</td><td>2 (7.7)</td><td>9 (2.3)</td><td>11 (2.6)</td></tr><tr><td>Familiar</td><td>4 (15.4)</td><td>18 (4.5)</td><td>22 (5.2)</td></tr><tr><td>Paramedical officer</td><td>0</td><td>13 (3.3)</td><td>13 (3.1)</td></tr><tr><td>Police</td><td>5 (19.2)</td><td>200 (50.0)</td><td>205 (48.1)</td></tr></table>
4aba1437212116ee21637faa0e74c51f35e53aba60af9333da9bd48c42e7dcac.png
simple
<table><tr><td>Age</td><td>87 years</td></tr><tr><td>Symptoms</td><td>Nocturnal leg cramps of moderate intensity since years. Since three weeks intensity of symptoms increased despite the use of quinine for symptomatic relief</td></tr><tr><td>Medical history</td><td>myocardial infarction in 2002 with consecutive coronary artery bypass graft (CABG)arterial hypertensionchronic kidney disease IIIknee replacement left + right.</td></tr><tr><td>Medication</td><td>aspirin 100 mg 1-0-0bisoprolol 2,5 mg 1-0-0ramipril 5 mg 1-0-0simvastatin 40 mg 0-0-1vitamin D3 1000 IU 1-0-0torasemide 5 mg 1-0-0fentanyl patch 12,5 &#956;g once every 3 days.Self-medication: quinine200 mg once daily</td></tr></table>
51124d6b98220126bb573979b2c23ccbcdb9b4b7272d38e9e7a353bc42844acc.png
simple
<table><tr><td>Possible outcome in eradication studies</td><td>How does the outcome affect reservoir measures?</td></tr><tr><td>1. Preferential reduction in intact proviruses</td><td>Integrated HV DNA is likely to be unchanged. Proviral sequencing would likely detect a reduction in the fraction of replication-competent proviruses which could be combined with integration measures to determine the absolute reduction in intact proviruses</td></tr><tr><td>2. Preferential reduction in defective proviruses</td><td>Integrated HIV DNA would decrease, without reflecting a contraction in the size of the &#8220;true&#8221; reservoir. Proviral sequencing would likely capture the change in the fraction of defective proviruses</td></tr><tr><td>3. Decrease in both intact and defective proviruses</td><td>If intact and defective proviruses are targeted differently, a decrease in integrated HIV DNA would occur, but would not likely be proportional to the decrease in the number of intact proviruses. Proviral sequencing combined with integration measures would likely capture the changes in the reservoir size and character</td></tr></table>
357f6042eea14aa029b6236018ad27c6c800064dbc7ae98c9b8d494e614d243e.png
complex
<table><tr><td rowspan="2">Time point</td><td rowspan="2"><i>N </i></td><td>PD</td><td rowspan="2"><i>F </i></td><td rowspan="2"><i>P</i> value</td></tr><tr><td>Mean &#177; SD</td></tr><tr><td>Baseline </td><td>25</td><td>61.04 &#177; 10.45</td><td rowspan="4">5.399 </td><td rowspan="4">0.00*</td></tr><tr><td>Second week </td><td>25</td><td>66.60 &#177; 10.74</td></tr><tr><td>Fourth week </td><td>25</td><td>69.64 &#177; 9.45</td></tr><tr><td>Sixth week </td><td>25</td><td>71.40 &#177; 8.23</td></tr></table>
d6dd840b6f55fd7ea40ddf944889853ad54ccfd0a89432bbb6378452330a2c50.png
simple
<table><tr><td>Paper</td><td>Country</td><td>Time period of breast cancer deaths</td><td>Cases (<i>n</i>)</td><td>Screening exposure</td><td>Crude Ors (95% CI)</td><td>ORs adjusted for self-selection bias</td></tr><tr><td>Allgood <i>et al. </i>[15]</td><td>UK</td><td>1995-2004</td><td>284</td><td>Ever/Never attendance before (pseudo) diagnosis</td><td>0.35 (0.24-0.51)</td><td>0.52 (0.32-0.84)</td></tr><tr><td>Fielder <i>et al. </i>[16]</td><td>Wales</td><td>1998-2001</td><td>419</td><td>Ever/Never attendance before (pseudo) diagnosis</td><td>0.62 (0.47-0.82)</td><td>0.75 (0.49-1.14)</td></tr><tr><td>Gabe <i>et al. </i>[17]</td><td>Iceland</td><td>1990-2002</td><td>226</td><td>Ever/Never attendance before (pseudo) diagnosis</td><td>0.59 (0.41-0.84)</td><td>0.65 (0.39-1.09)</td></tr><tr><td>Paap <i>et al. </i>[18]</td><td>Netherlands</td><td>2004-2005</td><td>118</td><td>Screened at index invitation</td><td>0.30 (0.14-0.63)</td><td>0.24 (0.10-0.58)</td></tr><tr><td>Puliti <i>et al. </i>[19]</td><td>Italy</td><td>1988-2002</td><td>1750</td><td>Ever/Never attendance before (pseudo) diagnosis</td><td>0.46 (0.38-0.56)</td><td>0.55 (0.36-0.85)</td></tr><tr><td>Roder <i>et al. </i>[20]</td><td>Australia</td><td>2002-2005</td><td>491</td><td>Ever/Never attendance before (pseudo) diagnosis</td><td>0.59 (0.47-0.74)</td><td>0.70<sup>a</sup></td></tr></table>
043c005716c0ccc0c0e990a6c0292774eb4f6d9b273825b4c21b0879413b1aa1.png
complex
<table><tr><td rowspan="2"></td><td>n (%)</td><td colspan="2">L1CAM expression n (%)</td><td>n (%)</td><td></td></tr><tr><td>Negative</td><td>&#8804; 20% of tumor cells</td><td>&gt;20% of tumor cells</td><td></td><td><i>P</i> value</td></tr><tr><td>Recurrence</td><td>9 (16)</td><td>14 (24)</td><td>34 (60)</td><td>57</td><td></td></tr><tr><td>No recurrence</td><td>24 (43)</td><td>19 (34)</td><td>13 (23)</td><td>56</td><td>&lt; 0.0001</td></tr></table>
9e28c1c9915104a5c92803c96f3960415c9fe1d0fb7c3bb42c974722d690bca9.png
simple
<table><tr><td>Class I (Positive)</td><td>Class II (Positive)</td></tr><tr><td>Cw10, B27, B57, B51, B61, B13, B44</td><td></td></tr><tr><td>B75, B55, Cw4, Cw12, B49, B38, Cw1</td><td></td></tr><tr><td>B76, B54, Cw16, B8, B48, B35, Cw15</td><td></td></tr><tr><td>B42, Cw7, Cw9, B41, B7, B62, Cw6</td><td></td></tr><tr><td>B82, B37, Cw17, B60, B56, B65, B45, B81</td><td>Negative</td></tr><tr><td>B59, B52, B39, Cw2, Cw14, B78, B46</td><td></td></tr><tr><td>Cw5, Cw8, B72, B58, B63, B77, B73</td><td></td></tr><tr><td>B71, B64, B53, B67, B47, B18, Cw18</td><td></td></tr><tr><td>B50, A11</td><td></td></tr></table>
9d32fcb392ee7b2ce6908073f9949b952a9966b9a1311a59289bb611e920447c.png
simple
<table><tr><td>Strains</td><td>Genes</td><td>Average <i>C</i><sub>t</sub></td><td>Average &#916;<i>C</i><sub>t</sub>&#177; SE</td><td>&#916;&#916;<i>C</i><sub>t</sub></td><td>RQ</td></tr><tr><td>WT</td><td><i>SPS18</i></td><td>28.701</td><td>6.369 &#177; 0.415</td><td>0</td><td>1</td></tr><tr><td></td><td><i>SPS19</i></td><td>22.432</td><td>0.101 &#177; 0.425</td><td>0</td><td>1</td></tr><tr><td></td><td><i>SMK1</i></td><td>30.164</td><td>7.832 &#177; 0.39</td><td>0</td><td>1</td></tr><tr><td></td><td><i>ACT1</i></td><td>22.331</td><td></td><td></td><td></td></tr><tr><td><i>oaf1</i>&#916;</td><td><i>SPS18</i></td><td>31.573</td><td>9.419 &#177; 0.383</td><td>3.049</td><td>0.121</td></tr><tr><td></td><td><i>SPS19</i></td><td>27.651</td><td>5.497 &#177; 0.121</td><td>5.396</td><td>0.024</td></tr><tr><td></td><td><i>SMK1</i></td><td>30.1</td><td>7.946 &#177; 0.293</td><td>0.114</td><td>0.924</td></tr><tr><td></td><td><i>ACT1</i></td><td>22.154</td><td></td><td></td><td></td></tr><tr><td><i>sum1</i>&#916;</td><td><i>SPS18</i></td><td>28.908</td><td>4.118 &#177; 0.916</td><td>&#8722;2.251</td><td>4.762</td></tr><tr><td></td><td><i>SPS19</i></td><td>24.793</td><td>0.003 &#177; 0.976</td><td>&#8722;0.098</td><td>1.07</td></tr><tr><td></td><td><i>SMK1</i></td><td>31.873</td><td>7.083 &#177; 0.985</td><td>&#8722;0.749</td><td>1.681</td></tr><tr><td></td><td><i>ACT1</i></td><td>24.79</td><td></td><td></td><td></td></tr><tr><td><i>sum1</i>&#916;<i>oaf1</i>&#916;</td><td><i>SPS18</i></td><td>29.109</td><td>6.552 &#177; 0.499</td><td>0.183</td><td>0.881</td></tr><tr><td></td><td><i>SPS19</i></td><td>25.45</td><td>2.893 &#177; 0.655</td><td>2.793</td><td>0.144</td></tr><tr><td></td><td><i>SMK1</i></td><td>29.943</td><td>7.386 &#177; 0.408</td><td>&#8722;0.446</td><td>1.362</td></tr><tr><td></td><td><i>ACT1</i></td><td>22.556</td><td></td><td></td><td></td></tr></table>
6028ef39e1838590c48c60c9da14631664ae35688f43ac87f9b3ac933e4cafd1.png
complex
<table><tr><td></td><td>Fully vaccinated, positive responses<sup>a</sup><i>n</i> = 75<i>n</i> (%)</td><td>Non-vaccinated positive responses<sup>a</sup><i>n</i> = 119<i>n</i> (%)</td><td>Fisher&#8217;s exact test<i>p</i>-value</td></tr><tr><td colspan="4">Knowledge items</td></tr><tr><td> HPV is a sexually transmitted infection</td><td>73 (97.3)</td><td>106 (89.8)</td><td>0.08</td></tr><tr><td> Men and women can be carriers of HPV</td><td>74 (98.7)</td><td>108 (91.5)</td><td>0.05</td></tr><tr><td> HPV vaccine protects against genital warts</td><td>58 (77.3)</td><td>86 (72.3)</td><td>0.50</td></tr><tr><td> HPV vaccine protects against cervical cancer</td><td>72 (96.0)</td><td>104 (87.4)</td><td>0.07</td></tr><tr><td> HPV vaccine protects against other cancers</td><td>36 (48.0)</td><td>56 (47.9)</td><td>1.00</td></tr><tr><td> HPV vaccine is safe</td><td>71 (95.9)</td><td>102 (85.7)</td><td>0.03*</td></tr><tr><td> HPV vaccine is effective</td><td>71 (95.9)</td><td>104 (87.4)</td><td>0.07</td></tr><tr><td> HPV vaccine has few side effects</td><td>64 (85.3)</td><td>83 (70.3)</td><td>0.02*</td></tr><tr><td> HPV vaccination leads to lasting immunity</td><td>49 (65.3)</td><td>58 (49.2)</td><td>0.04*</td></tr><tr><td> HPV vaccine is recommended for girls and boys</td><td>68 (90.7)</td><td>83 (70.3)</td><td>&lt;0.001*</td></tr><tr><td colspan="4">Attitude items</td></tr><tr><td> HPV vaccination may lead to risky sexual behavior</td><td>4 (5.3)</td><td>10 (8.4)</td><td>0.57</td></tr><tr><td> I have enough information to be able to counsel about HPV vaccine</td><td>35 (46.7)</td><td>45 (38.1)</td><td>0.29</td></tr><tr><td> I feel comfortable counseling about HPV vaccination</td><td>34 (45.3)</td><td>44 (37.3)</td><td>0.29</td></tr><tr><td> I would recommend the HPV vaccine to friends and family</td><td>73 (97.3)</td><td>81 (69.2)</td><td>&lt;0.001*</td></tr><tr><td> HPV vaccine should be mandatory</td><td>53 (72.6)</td><td>44 (38.3)</td><td>&lt;0.001*</td></tr></table>
1e076997eb048879482eaf91453eb5de83b9f792f61c3c40641ba82ee376a2d1.png
simple
<table><tr><td>Gene</td><td>Sequence (5' to 3')</td></tr><tr><td>Abcc4</td><td></td></tr><tr><td> - forward</td><td>TGCTTCCCAGACTCTGCACAAC</td></tr><tr><td> - reverse</td><td>AAGCAAGTCGTCCATGTGTCCG</td></tr><tr><td>Akr1c9</td><td></td></tr><tr><td> - forward</td><td>CAAGTGCCTTTGAATGCTGAGCC</td></tr><tr><td> - reverse</td><td>ACACCCACTTCATGCCCAAGAC</td></tr><tr><td>AR</td><td></td></tr><tr><td> - forward</td><td>AGAAAAAATCCCACATCCTGC</td></tr><tr><td> - reverse</td><td>CATCATTTCAGGAAAGTCCACG</td></tr><tr><td>Dhcr24</td><td></td></tr><tr><td> - forward</td><td>TGCTGAACTCCATTGGCTGGAC</td></tr><tr><td> - reverse</td><td>TTGTGGGACGATGACTCGATGC</td></tr><tr><td>Facl3</td><td></td></tr><tr><td> - forward</td><td>TCAGGCCAAGGCAAACTCCATTC</td></tr><tr><td> - reverse</td><td>TGCCAAAGCAAACTGGAGGAGG</td></tr><tr><td>Gucy1a3</td><td></td></tr><tr><td> - forward</td><td>AAGCTGAAGGCAACCTTGGAGC</td></tr><tr><td> - reverse</td><td>TTTGTCCTTGCCAGAGCTGCTG</td></tr></table>
a8816c7360250113a26b7e614795a324f893a858f8282f5c8aa5593dfdfa5314.png
simple
<table><tr><td></td><td>Proteins with high IS</td><td>P-value</td></tr><tr><td>100 most abundant proteins with IS in <i>L. interrogans</i></td><td>7</td><td>.0067</td></tr><tr><td>100 most abundant non-ribosomal proteins with IS in <i>L. interrogans</i></td><td>9</td><td>.033</td></tr><tr><td>100 most abundant non-ribosomal proteins with IS in <i>E. coli</i></td><td>6</td><td>.0013</td></tr><tr><td>100 most abundant non-ribosomal proteins with IS in <i>E. coli</i></td><td>9</td><td>.033</td></tr></table>
2e20dc7b49b3ef80c80df7c58ade0ba42228da671ae16c39ed0b0875ddcc1358.png
simple
<table><tr><td>Variables</td><td>Specificity (%)</td><td>Sensitivity (%)</td><td>PPV (%)</td><td>NPV (%)</td><td>AUC</td><td>YI</td><td>Best Cut-off</td><td><i>p</i></td></tr><tr><td>miR-3960</td><td>93.33</td><td>64.71</td><td>84.62</td><td>82.35</td><td>0.8333</td><td>0.624</td><td>18.96</td><td>&#8211;</td></tr><tr><td>miR-126-3p</td><td>86.67</td><td>35.29</td><td>60.00</td><td>70.27</td><td>0.7510</td><td>0.557</td><td>8.64</td><td>&#8211;</td></tr><tr><td>miR-335-5p</td><td>90.00</td><td>41.18</td><td>70.00</td><td>72.97</td><td>0.7294</td><td>0.388</td><td>15.67</td><td>&#8211;</td></tr><tr><td>miR-23a-3p</td><td>83.33</td><td>11.76</td><td>28.57</td><td>62.50</td><td>0.6275</td><td>0.331</td><td>14.24</td><td>&#8211;</td></tr><tr><td>miR-3960 + miR-126-3p</td><td>96.67</td><td>70.59</td><td>92.31</td><td>85.29</td><td>0.8529</td><td>0.673</td><td>&#8211;</td><td>0.567<sup>a</sup></td></tr></table>
ba41dedfd9f03b24e15b81c734d510cf4c9da959cd617316a04077d83d7ded5f.png
simple
<table><tr><td></td><td>Emergency</td><td>Elective</td><td>p-value</td></tr><tr><td>Recurrent PAD</td><td>2.61 (1.66, 4.10)</td><td>1.36 (0.99, 1.86)</td><td>0.0192</td></tr><tr><td>Incident PAD</td><td>2.29 (1.63, 3.22)</td><td>1.09 (0.81, 1.46)</td><td>0.0011</td></tr><tr><td>Recurrent CeVD</td><td>0.56 (0.40, 0.78)</td><td>0.62 (0.30, 1.26)</td><td>0.7973</td></tr><tr><td>Incident CeVD</td><td>0.42 (0.34, 0.51)</td><td>0.51 (0.29, 0.90)</td><td>0.4981</td></tr><tr><td>Recurrent CHD</td><td>1.29 (1.14, 1.46)</td><td>0.92 (0.77, 1.10)</td><td>0.0020</td></tr><tr><td>Incident CHD</td><td>1.00</td><td>1.00</td><td>-</td></tr></table>
661b5ff6c5d58f45e84179a57a9003c33bf2f4221e2681b748b4d351492ced4c.png
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<table><tr><td> </td><td>Children with ESRD</td></tr><tr><td> </td><td>(n=92)</td></tr><tr><td>Age (years)</td><td>13.1 (0.7-19.1)</td></tr><tr><td>Male*</td><td>51 (55%)</td></tr><tr><td>Weight (kilograms)</td><td>37.8 (4.3-96.0)</td></tr><tr><td>BSA (m<sup>2</sup>)</td><td>1.2 (0.4-2.2)</td></tr><tr><td>Height (cm)</td><td>138 (61&#8211;184)</td></tr><tr><td>Duration of RRT (years)</td><td>1.8 (0.0-6.8)</td></tr><tr><td>Modality at time of Echocardiography*</td><td> </td></tr><tr><td>-Hemodialysis</td><td>26 (28%)</td></tr><tr><td>-Peritoneal dialysis</td><td>24 (26%)</td></tr><tr><td>-Transplantation</td><td>42 (46%)</td></tr></table>
c9510355f637f2169ea8a1e8a6e786cce9b4f21f861a4d9fd1f80c156f9d986e.png
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<table><tr><td>Totle SNP</td><td>Non coding SNP</td><td>Coding SNP</td><td>Synonymous</td><td>Nonsynonymous</td></tr><tr><td>12,518</td><td>8863(70.80 %)</td><td>3655(29.20 %)</td><td>3632</td><td>23</td></tr></table>
5e6fc2d5ef90f4b578552827e3b11044f16d5f30ed49d20aa75e5f973a7e258c.png
complex
<table><tr><td rowspan="2"></td><td colspan="2">Incidence before varicella vaccination (per 1000 population)</td><td colspan="2">Reduction since varicella vaccination* (%)</td></tr><tr><td>USA</td><td>Uruguay</td><td>USA</td><td>Uruguay</td></tr><tr><td>&lt;1 year</td><td>19.7</td><td>14.3</td><td>68&#8211;81</td><td>63&#8211;80</td></tr><tr><td>1&#8211;4 years</td><td>48.8</td><td>56.7</td><td>83&#8211;90</td><td>94&#8211;97</td></tr><tr><td>5&#8211;9 years</td><td>34.5</td><td>41.6</td><td>63&#8211;77</td><td>73&#8211;81</td></tr><tr><td>10&#8211;14 years</td><td>9.5</td><td>13.2</td><td>65&#8211;80</td><td>62&#8211;65</td></tr></table>
5e958eb6e6bafa3d8f7aa9b77ce2ce8d0562ee5125b26d7f9a01832e54d7868c.png
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<table><tr><td rowspan="3">First author</td><td rowspan="3">Year</td><td rowspan="3">Country</td><td rowspan="3">Racial/descent</td><td rowspan="3">Source of controls</td><td rowspan="3">Case</td><td rowspan="3">Control</td><td colspan="6">Genotype distribution</td><td rowspan="3"><i>P</i>for HWE<sup>a</sup></td><td rowspan="3">Genotying type</td></tr><tr><td colspan="3">Case</td><td colspan="3">Control</td></tr><tr><td><i>GG</i></td><td><i>GA</i></td><td><i>AA</i></td><td><i>GG</i></td><td><i>GA</i></td><td><i>AA</i></td></tr><tr><td>Catarino</td><td>2005</td><td>Portugal</td><td>Caucasian</td><td>Healthy base</td><td>143</td><td>103</td><td>35</td><td>64</td><td>44</td><td>9</td><td>55</td><td>39</td><td>0.091</td><td>PCR-RFLP</td></tr><tr><td>Jeon</td><td>2005</td><td>Korean</td><td>Asian</td><td>Hospital base</td><td>222</td><td>314</td><td>49</td><td>112</td><td>61</td><td>80</td><td>160</td><td>74</td><td>0.730</td><td>PCR-RFLP</td></tr><tr><td>Catarino</td><td>2008</td><td>Portugal</td><td>Caucasian</td><td>Hospital base</td><td>226</td><td>247</td><td>60</td><td>103</td><td>63</td><td>40</td><td>138</td><td>69</td><td>0.037</td><td>PCR-RFLP</td></tr><tr><td>Satinder</td><td>2008</td><td>India</td><td>Asian</td><td>Healthy base</td><td>150</td><td>150</td><td>33</td><td>64</td><td>53</td><td>30</td><td>65</td><td>55</td><td>0.184</td><td>PCR-RFLP</td></tr><tr><td>Thakur</td><td>2009</td><td>India</td><td>Asian</td><td>Hospital base</td><td>200</td><td>200</td><td>39</td><td>94</td><td>67</td><td>47</td><td>119</td><td>34</td><td>0.006</td><td>PCR-RFLP</td></tr><tr><td>Castro</td><td>2009</td><td>Sweden</td><td>Caucasian</td><td>Population base</td><td>952</td><td>1713</td><td>229</td><td>463</td><td>260</td><td>465</td><td>837</td><td>411</td><td>0.367</td><td>Multiplex PCR and hybridization</td></tr><tr><td>Ni</td><td>2011</td><td>China</td><td>Asian</td><td>Hospital base</td><td>300</td><td>312</td><td>48</td><td>160</td><td>92</td><td>70</td><td>137</td><td>105</td><td>0.051</td><td>PCR-RFLP</td></tr><tr><td>Warcho&#322;</td><td>2011</td><td>Poland</td><td>Caucasian</td><td>Healthy base</td><td>129</td><td>288</td><td>35</td><td>65</td><td>29</td><td>116</td><td>123</td><td>49</td><td>0.100</td><td>PCR-RFLP</td></tr><tr><td>Wang</td><td>2012</td><td>China</td><td>Asian</td><td>Population base</td><td>327</td><td>411</td><td>86</td><td>180</td><td>61</td><td>92</td><td>203</td><td>116</td><td>0.859</td><td>PCR-RFLP</td></tr><tr><td>Djansugurova</td><td>2013</td><td>Kazakhstan</td><td>Caucasian</td><td>Healthy base</td><td>215</td><td>160</td><td>54</td><td>103</td><td>58</td><td>41</td><td>78</td><td>41</td><td>0.752</td><td>Direct sequencing</td></tr></table>
04f7a37c31cfc7be4d5b034ad4962448772224cfee04d26d16d686034de67782.png
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<table><tr><td></td><td>ASD</td><td>TD</td></tr><tr><td colspan="3">Head ROI</td></tr><tr><td> Implicit mentalizing-action</td><td>4.64 (9.68)</td><td>2.32 (12.01)</td></tr><tr><td> Implicit either-action</td><td>4.32 (8.00)</td><td>0.37 (11.08)</td></tr><tr><td> Explicit mentalizing-non-mentalizing<sup>a</sup></td><td>0.06 (18.05)</td><td>1.91 (13.13)</td></tr><tr><td colspan="3">Poker chip ROI</td></tr><tr><td> Implicit mentalizing-action</td><td>1.16 (6.15)</td><td>&#8722; 1.83 (8.76)</td></tr><tr><td> Implicit either-action</td><td>2.36 (5.58)</td><td>2.12 (11.96)</td></tr><tr><td> Explicit mentalizing-non-mentalizing<sup>a</sup></td><td>4.12 (15.89)</td><td>0.75 (6.21)</td></tr><tr><td colspan="3">Release point ROI</td></tr><tr><td> Implicit mentalizing-action</td><td>&#8722; 5.34 (3.98)</td><td>&#8722; 1.99 (5.52)</td></tr><tr><td> Implicit either-action</td><td>&#8722; 6.04 (4.24)</td><td>&#8722; 3.67 (4.76)</td></tr><tr><td> Explicit mentalizing-non-mentalizing<sup>a</sup></td><td>&#8722; 3.53 (6.81)</td><td>&#8722; 3.82 (2.70)</td></tr></table>
e6de0ec5fad7ec4654a64b07ab23f79e50eeae9fc4cb70fdd997060844d2a4c0.png
simple
<table><tr><td>Name</td><td>Genome size (Mbp)</td><td>GC Content (%)</td><td>Coverage (X)</td><td>Scaffolds</td><td>N50</td><td>Protein coding genes</td><td>Reference</td></tr><tr><td>AMDSBA1</td><td>4.56</td><td>52.19</td><td>258</td><td>155</td><td>65,127</td><td>4629</td><td>This study</td></tr><tr><td>AMDSBA2</td><td>3.07</td><td>52.37</td><td>10</td><td>409</td><td>10,877</td><td>3312</td><td>This study</td></tr><tr><td>AMDSBA3</td><td>3.68</td><td>55.54</td><td>113</td><td>129</td><td>49,240</td><td>3785</td><td>This study</td></tr><tr><td>AMDSBA4</td><td>4.11</td><td>51.67</td><td>25</td><td>179</td><td>63,277</td><td>4254</td><td>This study</td></tr><tr><td>AMDSBA5</td><td>3.65</td><td>49.15</td><td>92</td><td>161</td><td>65,096</td><td>3870</td><td>This study</td></tr><tr><td><i>S. thermosulfidooxidans</i> AT-1 (DSM 9293)</td><td>3.86</td><td>49.64</td><td>N/D</td><td>2</td><td>-</td><td>3875</td><td>IMG JGI</td></tr><tr><td><i>S. thermosulfidooxidans &#8216;</i>Cutipay&#8217;</td><td>3.86</td><td>49.30</td><td>116</td><td>35</td><td>509,367</td><td>3600</td><td>Travisany [16]</td></tr><tr><td><i>S. acidophilus</i> NAL<sup>T</sup> (DSM 10332)</td><td>3.56</td><td>56.75</td><td>168</td><td>1</td><td>-</td><td>3626</td><td>Anderson [17]</td></tr><tr><td><i>S. acidophilus</i> &#8216;TPY&#8217;</td><td>3.55</td><td>56.70</td><td>26</td><td>1</td><td>-</td><td>3770</td><td>Li [2]</td></tr></table>
30b3fc0bf3b4747ab18f60a8c4564e6eaece7703cf26bd0b54fbd897d8452e14.png
simple
<table><tr><td>Isolate No.</td><td>sex</td><td>Specimen</td><td>Date Of detection</td><td>STs</td><td>Carbapenemase</td><td>ESBL</td></tr><tr><td>TJ1</td><td>F</td><td>Sp</td><td>23/1/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ2</td><td>M</td><td>Bl</td><td>1/2/2015</td><td>ST888</td><td>NDM-1</td><td>CTX-15,TEM-1</td></tr><tr><td>TJ3</td><td>M</td><td>Ca</td><td>6/3/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ4</td><td>M</td><td>Bl</td><td>7/3/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-15</td></tr><tr><td>TJ5</td><td>M</td><td>Sp</td><td>15/7/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ6</td><td>M</td><td>Sp</td><td>16/7/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14</td></tr><tr><td>TJ7</td><td>F</td><td>Ur</td><td>18/7/2015</td><td>ST20</td><td>NDM-1</td><td>TEM-1</td></tr><tr><td>TJ8</td><td>M</td><td>Ca</td><td>4/8/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14</td></tr><tr><td>TJ9</td><td>M</td><td>Ca</td><td>8/8/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ10</td><td>F</td><td>Bl</td><td>11/8/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ11</td><td>M</td><td>Ur</td><td>26/8/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ12</td><td>M</td><td>Bl</td><td>31/8/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-15</td></tr><tr><td>TJ13</td><td>M</td><td>Bl</td><td>4/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ14</td><td>F</td><td>Ca</td><td>13/9/2015</td><td>ST20</td><td>NDM-1</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ15</td><td>M</td><td>Sp</td><td>13/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ16</td><td>M</td><td>Ca</td><td>22/9/2015</td><td>ST20</td><td>NDM-1</td><td>CTX-14</td></tr><tr><td>TJ17</td><td>F</td><td>Sp</td><td>25/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ18</td><td>F</td><td>Ur</td><td>30/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ19</td><td>M</td><td>Bl</td><td>2/10/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ20</td><td>F</td><td>Ur</td><td>6/10/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ21</td><td>M</td><td>Ur</td><td>8/10/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ22</td><td>F</td><td>Ur</td><td>12/10/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ23</td><td>M</td><td>Bl</td><td>25/10/2015</td><td>ST11</td><td>KPC-2</td><td>&#8211;</td></tr><tr><td>TJ24</td><td>M</td><td>Bl</td><td>28/10/2015</td><td>ST20</td><td>NDM-1</td><td>CTX-14</td></tr><tr><td>TJ25</td><td>F</td><td>Ur</td><td>20/11/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ26</td><td>F</td><td>Bl</td><td>20/11/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14</td></tr><tr><td>TJ27</td><td>M</td><td>Ur</td><td>21/11/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ28<sup>a</sup></td><td>&#8211;</td><td>Radiant warmer</td><td>8/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ29<sup>a</sup></td><td>&#8211;</td><td>Radiant warmer</td><td>8/9/2015</td><td>ST20</td><td>NDM-1</td><td>CTX-14</td></tr><tr><td>TJ30<sup>b</sup></td><td>&#8211;</td><td>Nurses hand</td><td>8/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ31<sup>c</sup></td><td>&#8211;</td><td>Radiant warmer</td><td>8/9/2015</td><td>ST11</td><td>KPC-2</td><td>CTX-14,TEM-1</td></tr><tr><td>TJ32<sup>b</sup></td><td>&#8211;</td><td>Nurses hand</td><td>8/9/2015</td><td>ST20</td><td>NDM-1</td><td>CTX-14</td></tr></table>
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complex
<table><tr><td> </td><td colspan="2">Frequency of complication</td><td colspan="2">In-hospital deaths</td><td colspan="2">Relative risk of in-hospital death</td></tr><tr><td> </td><td>N</td><td>%</td><td>N</td><td>%</td><td>Adj. RR</td><td>95% CI</td></tr><tr><td>No complication</td><td>18,415</td><td>77.5</td><td>108</td><td>0.6</td><td> </td><td> </td></tr><tr><td>Complication</td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>Gastrointestinal</td><td>263</td><td>1.1</td><td>18</td><td>6.8</td><td>3.61</td><td>2.32-5.63</td></tr><tr><td>Respiratory</td><td>636</td><td>2.7</td><td>44</td><td>6.9</td><td>2.05</td><td>1.30-3.03</td></tr><tr><td>Urologic</td><td>546</td><td>2.3</td><td>102</td><td>18.7</td><td>3.62</td><td>2.62-5.00</td></tr><tr><td>Infection</td><td>449</td><td>1.9</td><td>18</td><td>4.0</td><td>2.45</td><td>1.47-4.07</td></tr><tr><td>Bleeding or acute posthaemorrhage anemia</td><td>4,371</td><td>18.4</td><td>188</td><td>4.3</td><td>2.11</td><td>1.73-2.57</td></tr><tr><td>Bleeding or acute posthaemorrhage anemia requiring blood transfusion</td><td>3,086</td><td>13.0</td><td>157</td><td>5.1</td><td>1.96</td><td>1.57-2.44</td></tr></table>
89205010bdd7ac1a8ce64d5c4506076e9f2963e5e4a5f1108a3a806ecbf03201.png
simple
<table><tr><td>Transformable isolate<sup>b</sup></td><td>Phylogenetic position</td><td>Plasmids tested</td><td>16S-rRNA gene identity<sup>c</sup></td></tr><tr><td><i>Marinobacter </i>sp.</td><td>Gammaproteobacteria;</td><td>pM1, pM2,</td><td>77</td></tr><tr><td></td><td><i>Alteromonadales</i></td><td>pM3</td><td></td></tr><tr><td><i>Kocuria rosea</i></td><td>Actinobacteria;</td><td>pM2</td><td>79</td></tr><tr><td><i>Photobacterium</i></td><td>Gammaproteobacteria;</td><td>pM1, pM2,</td><td>86</td></tr><tr><td><i>phosphoreum</i></td><td><i>Vibrionales</i></td><td>pM3</td><td></td></tr><tr><td><i>Psychrobacter</i></td><td>Gammaproteobacteria;</td><td>pM1, pM2,</td><td>96</td></tr><tr><td><i>marincola</i></td><td><i>Pseudomonadales</i></td><td>pM3</td><td></td></tr></table>
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complex
<table><tr><td></td><td colspan="3">Cardinal clinical feature</td><td></td></tr><tr><td></td><td>Ataxia(n = 54)</td><td>Tremor(n = 4)</td><td>Cognitive deficits(n = 28)</td><td><i>Total</i>(N = 86)</td></tr><tr><td>Age (mean &#177; SD)</td><td>67.7 &#177; 9.1</td><td>59.0 &#177; 8.6</td><td>70.0 &#177; 9.2</td><td>68.0 &#177; 9.3</td></tr><tr><td>Age-of-onset (mean &#177; SD)</td><td>59.0 &#177; 6.8</td><td>54.0 &#177; 1.4</td><td>60.5 &#177; 6.7</td><td>59.2 &#177; 6.7</td></tr><tr><td>With additional cardinal features (<i>n</i>)</td><td>13</td><td>1</td><td>4</td><td>18</td></tr><tr><td>Family history (<i>n</i>)</td><td></td><td></td><td></td><td></td></tr><tr><td><i>None</i></td><td>33</td><td>3</td><td>14</td><td>50</td></tr><tr><td><i>Unknown</i></td><td>21</td><td>1</td><td>14</td><td>36</td></tr></table>
44d4545f04adce13a1d645b2555b1d2e068dfd99ae01f668842a055f66e24b84.png
simple
<table><tr><td>Variable</td><td>Mothers</td><td>Fathers</td></tr><tr><td></td><td>Mean (sd)</td><td>Mean (sd)</td></tr><tr><td>Age (when index child born)</td><td>33.2 (4.7)</td><td>34.7 (5.7)</td></tr><tr><td>Parental education:</td><td></td><td></td></tr><tr><td>No qualifications</td><td>&#8211;</td><td>1 (0.7%)</td></tr><tr><td>GCSE</td><td>8 (5.5%)</td><td>13 (8.9%)</td></tr><tr><td>A levels or equivalent</td><td>14 (9.6%)</td><td>13 (8.9%)</td></tr><tr><td>Diploma or equivalent degree</td><td>27 (18.5%)</td><td>25 (17.1%)</td></tr><tr><td>Degree</td><td>46 (31.5%)</td><td>51 (34.9%)</td></tr><tr><td>Postgraduate</td><td>46 (31.5%)</td><td>40 (27.4%)</td></tr><tr><td>Missing</td><td>5 (3.4%)</td><td>3 (2.0%)</td></tr><tr><td>Parental occupation:</td><td></td></tr><tr><td>Managerial/professional</td><td>81 (55.5%)</td></tr><tr><td>Intermediate occupations</td><td>39 (26.7%)</td></tr><tr><td>Routine/manual</td><td>25 (17.1%)</td></tr><tr><td>Unemployed</td><td>1 (0.7%)</td></tr></table>
65e364bb7cb842ad558188d960e09204dc9fc30508b86d06c41763a5a012b011.png
complex
<table><tr><td>Cox proportional hazard ratios</td><td>Sites discovered before E.O. [Exp(B)]</td><td>Chance of listing (%)a</td><td>Sites discovered after E.O. Exp(B)</td><td>Chance of listing (%)a</td></tr><tr><td colspan="5">Marginalized populations</td></tr><tr><td> Hispanic (%)</td><td>1.002</td><td>2</td><td>1.005</td><td>5</td></tr><tr><td> American Indian (%)</td><td>1.003</td><td>3</td><td>0.923</td><td>&#8722;77</td></tr><tr><td> Minority (%)</td><td>0.998</td><td>&#8722;2</td><td>0.993</td><td>&#8722;7</td></tr><tr><td> Institutionalized population (%)</td><td>1.002</td><td>2</td><td>0.998</td><td>&#8722;2</td></tr><tr><td> Elder population (%)</td><td>0.999</td><td>&#8722;1</td><td>1.042</td><td>42</td></tr><tr><td colspan="5">Wealth and power indicators</td></tr><tr><td> Mean family income ($1,000s)</td><td>1.004</td><td>4</td><td>1.004</td><td>4</td></tr><tr><td> Mean value of housing ($1,000s)</td><td>0.999</td><td>&#8722;1</td><td>1.006</td><td>6</td></tr><tr><td> Owned housing (%)</td><td>1.001</td><td>1</td><td>1.019</td><td>19</td></tr><tr><td> Professional careers (%)</td><td>1.007</td><td>7</td><td>0.934</td><td>&#8722;66</td></tr><tr><td> College degree or higher (%)</td><td>1.001</td><td>1</td><td>0.975</td><td>&#8722;25</td></tr><tr><td> No high school diploma (%)</td><td>1.000</td><td>0</td><td>1.010</td><td>10</td></tr><tr><td> Below the poverty line (%)</td><td>0.984</td><td>&#8722;16</td><td>0.969</td><td>&#8722;31</td></tr><tr><td colspan="5">Gender and family</td></tr><tr><td> Female headed households (%)</td><td>1.005</td><td>5</td><td>1.048</td><td>48</td></tr><tr><td> Children &lt; 18 (%)</td><td>1.000</td><td>0</td><td>0.991</td><td>&#8722;9</td></tr><tr><td colspan="5">Urbanization</td></tr><tr><td> Population density</td><td>1.000</td><td>0</td><td>1.000</td><td>0</td></tr><tr><td> Urban</td><td>0.998</td><td>&#8722;2</td><td>1.002</td><td>2</td></tr><tr><td colspan="5">Site-specific characteristics</td></tr><tr><td> PRPs identified</td><td>1.344</td><td>134</td><td>0.617</td><td>62</td></tr><tr><td> Hazardous ranking score</td><td>0.977</td><td>&#8722;23</td><td>0.987</td><td>&#8722;13</td></tr><tr><td colspan="5">Cases</td></tr><tr><td> Listed</td><td>1,410</td><td></td><td>53</td><td></td></tr><tr><td> Censored</td><td>48</td><td></td><td>8</td><td></td></tr><tr><td> Total</td><td>1,458</td><td></td><td>61</td><td></td></tr><tr><td> Missing</td><td>21</td><td></td><td>0</td><td></td></tr></table>
4602441f8a7c1d3784427df348a8070b833f3b9cbffa0456529dde3b4091171d.png
simple
<table><tr><td>Plant family/Plant sample - Herbarium voucher number</td><td>Traditional use</td><td>Part used in this study</td><td>Potential active compounds characterized</td><td>Previously screened activity</td></tr><tr><td>APOCYNACEAE<i>/Alstonia boonei</i> De Wild &#8211; 43368/HNC</td><td>Fever, painful micturition, insomnia, chronic diarrhea, rheumatic pains, anti-venom (snake bites), malaria, diabetes, helminths, arthritis [28, 29].</td><td>Leaves, bark</td><td>Echitamine, echitamidine, Voacangine, akuammidine, N- <i>&#945;</i>-formylechitamidine, N<i>- &#945;</i>-formyl-12-methoxyechitamidine [29].</td><td>Antimalarial, antioxidant, analgesic, anti-inflammatory, antipyretic [30&#8211;32].</td></tr><tr><td><i>APOCYNACEAE/Catharanthus roseus</i> L. &#8211; 5689/HNC.</td><td>Bleeding arresting, diabetes, fever, rheumatism, cancer [20, 33].</td><td>Leaves, stem</td><td>Vincristine, vinblastine, benzoic acid, p-hydroxybenzoic acid, salicylic acid, 2,3-dihydroxybenzoic acid, 2,5-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid, 3,5-dihydroxybenzoic acid, gallic acid, vanillic acid, chlorogenic acid, kaemferol trisaccharides, Quercetin trisaccharides, Syringetin glycosides [20, 34].</td><td>Wound-healing, antimicrobial, hypoglycemic, antioxidant [18, 20, 33].</td></tr><tr><td>ASTERACEAE<i>/Ageratum conyzoi&#776;des</i> Linn. &#8211; 19050/SFR-Cam</td><td>Purgative, fever, ulcers, wound, mental, infectious diseases, headaches, anti-inflammatory, diarrhea [35, 36].</td><td>Whole plant</td><td><i>&#946;</i>-caryophyllene, precocene I, friedelin, Lycopsamine, echinatine,<i>&#946;</i>-sitosterol, stigmasterol, 5-methoxynobiletin, linderoflavone B, eupalestin, sabinene, <i>&#945;</i> and <i>&#946;</i> pinene, <i>&#946;</i>-phellandrene, 1,8-cineole and limonene, ocimene, eugenol [35].</td><td>Antimicrobial, anticonvulsant, analgesic, anti-inflammatory, antipyretic, insecticidal, antioxidant, antiplasmodial, cytotoxic [35, 37, 38].</td></tr><tr><td>EUPHORBIACEAE<i>/Croton macrostachys</i> Hochst. &#8211; 40501/HNC</td><td>Malaria, antidiabetic, purgative mastitis, wounds, gastrointestinal Complications [39&#8211;41].</td><td>Leaves</td><td>Neoclerodan-5,10-en-19,6<i>&#946;</i>;20,12-diolide; 3<i>&#945;</i>,19-Dihydroxytrachylobane; 3<i>&#945;</i>,18,19-Trihydroxytrachylobane, lupeol, lupenone, betulinic acid, 28-<i>O</i>-acetylbetulin, betulin, lupeol acetate, zeorin, benzoic acid, methyl gallate, methyl 2,4-dihydroxy-3,6-dimethylbenzoate, lichexanthone, <i>&#946;</i>-sitosterol, and <i>&#946;</i>-sitosterol palmitate, stigmasterol, botulin, crotepoxide [42, 43].</td><td>Antimicrobial, antimalarial, cytotoxic [38, 39, 41].</td></tr><tr><td>FABACEAE<i>/Cassia obtusifolia</i> L. &#8211; 39847/HNC</td><td>Laxative, eye infections, diarrhea, urinary tract infections, gingivitis, fever, cough [25].</td><td>Whole plant</td><td>aloe-emodin, 1-methylaurantio-obtusin-2-<i>O-&#946;</i>-<sub>D</sub>-glucopyranoside, emodin, 1,2- dihydroxyanthraquinone, obtusin, chrysoobtusin, aurantioobtusin, gluco-obtusifolin, glucoaurantioobtusin, gluco-chryso-obtusin, 1-desmethylaurantio-obtusin, 1-desmethylaurantio-obtusin-2-<i>O-&#946;</i>- <sub>D</sub>-glucopyranoside, 1-desmethylchryso-obtusin, 1-desmethyl-obtusin, aurantio-obtusin-6-<i>O-&#946;</i>-<sub>D</sub>-glucopyranoside, alaternin-1-<i>O-&#946;</i>-<sub>D</sub>-glucopyranoside, chrysoobtusin-2-<i>O-&#946;</i>-<sub>D</sub>-glucopyranoside physicon-8-<i>O-&#946;</i>-<sub>D</sub>-glucoside, obtusifolin, <i>O</i>-methyl-chrysophanol, emodin-1-<i>O-&#946;</i>-gentio-bioside, chrysophanol-1-<i>O-&#946;</i>-gentiobioside, physcion-8-O-&#946;-gentiobioside, physcion-8-<i>O-&#946;</i>-glucoside, chrysophanol-1-<i>O-&#946;</i>-<sub>D</sub>-glucopyranosyl-(13)-<i>&#946;</i>-<sub>D</sub>-glucopyranosyl-(1 &#8594; 6)-<i>&#946;</i>-<sub>D</sub>-glucopyranoside, chrysophanic acid, physcion, questin, 1,3-dihydroxy-8-methylanthraquinone, chrysophanol- 10,10&#8242;-bianthrone, torosachrysone [44].</td><td>Antibacterial, antifungal, mosquito larvicidal activity, platelet antiaggregatory, neuroprotective [25, 45&#8211;47].</td></tr><tr><td>SAPINDACEAE<i>/Paullinia pinnata</i> L. &#8211; 10702/SRF-Cam</td><td>Malaria, erectile dysfunction [24].</td><td>Leaves, stem</td><td>Paullinoside A, paullinomides A and B, <i>&#946;</i>-amyrin, 13&#946;,17<i>&#946;</i>-dihydroxy-28-norolean-12-ene, <i>&#946;</i>-sitosterol glucopyranoside, 2-<i>O</i>-methyl-L-chiro-inositol, L-quebrachitol, <i>&#946;</i>-sitosterol, friedelin, daucosterol, aridanin, lotoidoside [24, 48].</td><td>Antiparasitic, antimicrobial, cytotoxic [24, 38, 49].</td></tr></table>
7d0597fb9cc8d1a9fe6794d327b45fcf084f76abb0b48f0d56a6637262d8c45e.png
complex
<table><tr><td>Age (Year)</td><td>Calibration Model</td><td>Total Body Burden (Bq)</td><td>Estimated Total Uptake (Bq)</td><td>24-h Thyroid Uptake (%)</td></tr><tr><td rowspan="2">53</td><td>Homogenous</td><td>3927 &#177; 135</td><td>4243 &#177; 146</td><td>-</td></tr><tr><td>Thyroid and others</td><td>3716 &#177; 128</td><td>4015 &#177; 138</td><td>&lt;7.2 &#177; 1.1</td></tr><tr><td rowspan="2">49</td><td>Homogenous</td><td>2321 &#177; 165</td><td>2508 &#177; 178</td><td>-</td></tr><tr><td>Thyroid and others</td><td>2320 &#177; 165</td><td>2507 &#177; 178</td><td>&lt;10.7 &#177; 3.8</td></tr><tr><td rowspan="2">35</td><td>Homogenous</td><td>3918 &#177; 127</td><td>4233 &#177; 137</td><td>-</td></tr><tr><td>Thyroid and others</td><td>4050 &#177; 131</td><td>4376 &#177; 142</td><td>&lt;16.7 &#177; 2.7</td></tr><tr><td rowspan="2">34</td><td>Homogenous</td><td>1284 &#177; 182</td><td>1387 &#177; 197</td><td>-</td></tr><tr><td>Thyroid and others</td><td>1140 &#177; 162</td><td>1232 &#177; 175</td><td>&lt;49.9 &#177; 11.0</td></tr><tr><td rowspan="2">27</td><td>Homogenous</td><td>2623 &#177; 195</td><td>2834 &#177; 211</td><td>-</td></tr><tr><td>Thyroid and others</td><td>2454 &#177; 182</td><td>2652 &#177; 197</td><td>&lt;44.1 &#177; 5.8</td></tr></table>
037f1667641032e002dae5142b16d7c0b22eaceb39b93f61ee451c764b4e648f.png
complex
<table><tr><td rowspan="2" colspan="2"></td><td colspan="3">t3</td><td></td></tr><tr><td>No/little burden</td><td>Moderate burden</td><td>(Very) severe burden</td><td></td></tr><tr><td rowspan="3">t1</td><td>No/little burden</td><td>22</td><td>3</td><td>0</td><td>25 (48.1 %)</td></tr><tr><td>Moderate burden</td><td>7</td><td>8</td><td>3</td><td>18 (34.6 %)</td></tr><tr><td>(Very) severe burden</td><td>0</td><td>4</td><td>5</td><td>9 (17.3 %)</td></tr><tr><td></td><td></td><td>29 (55.8 %)</td><td>15 (28.8 %)</td><td>8 (15.4 %)</td><td>52 (100 %)</td></tr></table>
3b6dd74d495f5866c42cbcfac52ede2100c04762a49ac237c51946d85741dadd.png
simple
<table><tr><td>Genotypes</td><td>SCA-HU<sup>+</sup> patients<i>N</i> (%)</td><td>SCA-HU<sup>&#8722;</sup> patients<i>N</i> (%)</td><td>OR(95% CI)</td><td><i>p</i> value</td></tr><tr><td><i>MPO &#8722;463G&gt;A</i></td><td><i>N</i> = 35 (100%)</td><td><i>N</i> = 66 (100%)</td><td></td><td></td></tr><tr><td> GG</td><td>10 (28.57%)</td><td>34 (51.52%)</td><td>2.66</td><td>0.045<sup>&#8727;</sup></td></tr><tr><td> GA + AA</td><td>25 (71.43%)</td><td>32 (48.48%)</td><td>(1.10&#8211;6.39)</td><td></td></tr><tr><td><i>NQO1 609C&gt;T</i></td><td><i>N</i> = 35 (100%)</td><td><i>N</i> = 67 (100%)</td><td></td><td></td></tr><tr><td> CC</td><td>24 (68.57%)</td><td>41 (61.19%)</td><td>0.72</td><td>0.604<sup>&#8727;</sup></td></tr><tr><td> CT + TT</td><td>11 (31.43%)</td><td>26 (38.81%)</td><td>(0.30&#8211;1.72)</td><td></td></tr><tr><td><i>CYP2E1 &#8722;1293G&gt;C/&#8722;1053C&gt;T</i></td><td><i>N</i> = 35 (100%)</td><td><i>N</i> = 67 (100%)</td><td></td><td></td></tr><tr><td> c1c1</td><td>26 (74.29%)</td><td>63 (94.03%)</td><td>5.45</td><td>0.009<sup>&#8727;&#8727;</sup></td></tr><tr><td> c1c2 + c2c2</td><td>9 (25.71%)</td><td>4 (5.97%)</td><td>(1.54&#8211;19.28)</td><td></td></tr><tr><td><i>GSTT1</i></td><td><i>N</i> = 35 (100%)</td><td><i>N</i> = 67 (100%)</td><td></td><td></td></tr><tr><td> <i>GSTT1</i>+</td><td>26 (74.29%)</td><td>49 (73.13%)</td><td>0.94</td><td>0.911<sup>&#8727;</sup></td></tr><tr><td> <i>GSTT1&#8722;</i></td><td>9 (25.71%)</td><td>18 (26.87%)</td><td>(0.37&#8211;2.39)</td><td></td></tr><tr><td><i>GSTM1</i></td><td><i>N</i> = 35 (100%)</td><td><i>N</i> = 67 (100%)</td><td></td><td></td></tr><tr><td> <i>GSTM1</i>+</td><td>21 (60%)</td><td>45 (67.16%)</td><td>1.36</td><td>0.616<sup>&#8727;</sup></td></tr><tr><td> <i>GSTM1&#8722;</i></td><td>14 (40%)</td><td>22 (32.84%)</td><td>(0.58&#8211;3.18)</td><td></td></tr></table>
111e79164331da48aaa3838b257b6bd2d7f12692a9f29e1d418a0f7de6f80125.png
complex
<table><tr><td></td><td colspan="2">Baseline (Awake)</td><td colspan="2">Baseline (Urethane) 10-20 min</td><td colspan="2">Formalin 1<sup><i>st</i></sup> phase (0-10 min)</td><td colspan="2">Formalin 2<sup><i>nd</i></sup> phase (10-60 min)</td></tr><tr><td></td><td>FR(d/s)</td><td>Ratio(%)</td><td>FR(d/s)</td><td>Ratio(%)</td><td>FR(d/s)</td><td>Ratio(%)</td><td>FR(d/s)</td><td>Ratio(%)</td></tr><tr><td>Overall</td><td>5.25 &#177; 0.80</td><td></td><td>0.64 &#177; 0.24</td><td></td><td>1.14 &#177; 0.57</td><td></td><td>1.22 &#177; 0.14</td><td></td></tr><tr><td>Tonic</td><td>5.08 &#177; 0.80</td><td>96.65</td><td>0.64 &#177; 0.24</td><td>100.00</td><td>1.09 &#177; 0.57</td><td>95.73</td><td>1.12 &#177; 0.14</td><td>91.99</td></tr><tr><td>Burst Spike</td><td>0.17 &#177; 0.03</td><td>3.35</td><td>0.00 &#177; 0.00</td><td>0.0</td><td>0.05 &#177; 0.52</td><td>4.27</td><td>0.10 &#177; 0.01</td><td>8.01</td></tr></table>
036e634dd6c16fbf09b35c878d62d511d60cd6d3b5e819d06dbcf6e1b5a260ef.png
complex
<table><tr><td>Outcome measures</td><td>B</td><td>3 m</td><td>6 m</td><td>9 m</td><td>12 m</td><td>R</td></tr><tr><td colspan="7">Questionnaires</td></tr><tr><td colspan="7"><i>Patient</i></td></tr><tr><td>CCQ</td><td>X</td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>MRC dyspnea</td><td>X</td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>SGRQ</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>McGill QOL</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>HADS</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>Illness understanding</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>Demographic questionnaire</td><td>X</td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="7"><i>Informal caregiver</i></td></tr><tr><td>SPPIC</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>HADS</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>Illness understanding</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td><td> </td></tr><tr><td>Demographic questionnaire</td><td>X</td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td><i>Lung specialist</i></td><td> </td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>CRF</td><td>X</td><td> </td><td> </td><td> </td><td> </td><td> </td></tr><tr><td colspan="7">Medical files</td></tr><tr><td>Number of hospitalisations of unexpected hospital admissions for AECOPD</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Number of days of unexpected hospital admissions for AECOPD</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Number of hospitalisations of unexpected ICU admissions for AECOPD</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Number of days of unexpected ICU admissions for AECOPD</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Are the choices of ACP documented in the medical file at baseline? (when yes/when no)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Are the choices of ACP documented in the medical file after one year or at time of death? (when yes/when no)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Did the patient die within one year after inclusion? (when yes/when no)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Date of death</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Place of death (ICU/hospital/hospice/nursing home/at home)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Is preferred place of death known? (when yes/when no)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Has this wish come true? (when yes/when no)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Primary cause of death (pulmonary insufficiency/other cause)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Secondary cause of death (pulmonary insufficiency/other cause)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Did the patient have an unexpected hospital readmission for AECOPD within 8 weeks? (when yes/when no)</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr><tr><td>Date of first unexpected hospital readmission for AECOPD.</td><td> </td><td> </td><td> </td><td> </td><td> </td><td>X</td></tr></table>
5cc4cc5f67d786c4a9665e8b3dc533744f1a273a2901ef2026765e743a003316.png
simple
<table><tr><td> </td><td>Botanical name</td><td>Family</td><td>Common name</td><td>Density (ind/hectare) mean &#177; stdv</td><td>Uses</td></tr><tr><td>1</td><td><i>Virola surinamensis</i> (Rol.) Warb.</td><td>Myristicaceae</td><td>Urucurana</td><td>97.3 &#177; 97.1</td><td>M, T, O</td></tr><tr><td>2</td><td><i>Xylopia brasiliensis</i> Sprengel</td><td>Annonaceae</td><td>Pindai&#769;ba</td><td>63.3 &#177; 60.3</td><td>-</td></tr><tr><td>3</td><td><i>Carapa guianesenis</i> Aubl.</td><td>Meliaceae</td><td>Andiroba</td><td>46.7 &#177; 50.3</td><td>M, T, O</td></tr><tr><td>4</td><td><i>Symphonia globulifera</i> Linn. f.</td><td>Clusiaceae</td><td>Guanandi/Guananim</td><td>43.4 &#177; 40.4</td><td>M, T</td></tr><tr><td>5</td><td><i>Mauritia flexuosa</i> L.F.</td><td>Arecaceae</td><td>Buriti</td><td>33.3 &#177; 32.1</td><td>F, S</td></tr><tr><td>6</td><td><i>Euterpe oleraceae</i> Mart.</td><td>Arecaceae</td><td>Juc&#807;ara/Ac&#807;ai</td><td>33.3 &#177; 43.6</td><td>F, H</td></tr><tr><td>7</td><td><i>Richeria dressleri</i> G.L. Webster</td><td>Phyllanthaceae</td><td>Jaca-da-baixa</td><td>30.0 &#177; 43.6</td><td>-</td></tr><tr><td>8</td><td><i>Anacardium sp.</i></td><td>Anacardiaceae</td><td>Caju-da-baixa</td><td>26.7 &#177; 46.2</td><td>F</td></tr><tr><td>9</td><td>n.i.</td><td>n.i.</td><td>Casca-grossa</td><td>20.0 &#177; 34.6</td><td>-</td></tr><tr><td>10</td><td><i>Attalea maripa</i> (Aubl.) Mart</td><td>Arecaceae</td><td>Inaja&#769;</td><td>16.7 &#177; 15.3</td><td>F, H, O</td></tr><tr><td>11</td><td><i>Tapirira guianensis</i> Aubl.</td><td>Anacardiaceae</td><td>Pau-pombo</td><td>16.7 &#177; 15.3</td><td>-</td></tr><tr><td>12</td><td><i>Annona sp</i></td><td>Annonaceae</td><td>Araticum-da-baixa</td><td>13.3 &#177; 5.8</td><td>F</td></tr></table>
95d6f29b167da4e62b05f66aa946621f62d40e569935cff4ed07e648a34d2142.png
complex
<table><tr><td>Polymorphism</td><td>Strand</td><td>Primer sequence</td></tr><tr><td rowspan="2">rs429358 (<i>APOE</i>)</td><td>Sense</td><td>5&#8242;-GAACTGGAGGAACAACTGAC</td></tr><tr><td>Antisense</td><td>5&#8242;-CGCTCGCGGATGGCGCTGA</td></tr><tr><td rowspan="2">rs7412 (<i>APOE</i>)</td><td>Sense</td><td>5&#8242;-GAACTGGAGGAACAACTGAC</td></tr><tr><td>Antisense</td><td>5&#8242;-CGCTCGCGGATGGCGCTGA</td></tr><tr><td rowspan="2">rs4680 (<i>COMT</i>)</td><td>Sense</td><td>5&#8242;-GCTACTCAGCTGTGCGCATG</td></tr><tr><td>Antisense</td><td>5&#8242;-ACGTGGTGTGAACACCTGGT</td></tr><tr><td rowspan="2">SL6A3 repeat (<i>DAT1</i>)</td><td>Sense</td><td>5&#8242;-TGTGTGCGTGCATGTGG</td></tr><tr><td>Antisense</td><td>5&#8242;-GCTTGGGGAAGGAAGGG</td></tr><tr><td rowspan="2">rs1108580 (<i>DBH</i>)</td><td>Sense</td><td>5&#8242;-ACGCCTGGAGTGACCAGAAG</td></tr><tr><td>Antisense</td><td>5&#8242;-CCATCCTCCTTGGCTTTCTC</td></tr><tr><td rowspan="2">rs747302 (<i>DRD4</i>)</td><td>Sense</td><td>5&#8242;-CGGAGGGAATGGAGGAGGGA</td></tr><tr><td>Antisense</td><td>5&#8242;-AGACCTGAGCTCAGGCTCTG</td></tr></table>
cf6ea49d35133995eb0e61df07c8efea4708ba1e7f0692a8b284eba933c85c66.png
simple
<table><tr><td>Variable</td><td>OR</td><td>95% CI</td></tr><tr><td><i>Age</i></td><td></td><td></td></tr><tr><td> 17&#8211;24</td><td>1.2</td><td>0.49, 3.1</td></tr><tr><td> 25&#8211;34</td><td>1.0</td><td></td></tr><tr><td> 35 and over</td><td>0.84</td><td>0.29, 2.4</td></tr><tr><td><i>First Pregnancy</i></td><td></td><td></td></tr><tr><td> No</td><td>1.0</td><td></td></tr><tr><td> Yes</td><td>0.75</td><td>0.29, 1.9</td></tr><tr><td><i>Highest Level of Education Completed</i></td><td></td><td></td></tr><tr><td> Less than Secondary School</td><td>1.0</td><td></td></tr><tr><td> Secondary School or Beyond</td><td>3.4*</td><td>1.6, 7.3</td></tr><tr><td><i>Number of Durable Goods Owned</i></td><td></td><td></td></tr><tr><td> 0</td><td>1.0</td><td></td></tr><tr><td> 1&#8211;2</td><td>2.2</td><td>0.60, 7.8</td></tr><tr><td> 3&#8211;4</td><td>3.1</td><td>0.80, 11</td></tr><tr><td><i>Employment Status</i></td><td></td><td></td></tr><tr><td> Never had a job</td><td>1.0</td><td></td></tr><tr><td> Currently unemployed</td><td>1.1</td><td>0.41, 2.8</td></tr><tr><td> Currently employed</td><td>0.62</td><td>0.28, 1.4</td></tr><tr><td><i>Living with Partner</i></td><td></td><td></td></tr><tr><td> No</td><td>1.0</td><td></td></tr><tr><td> Yes</td><td>0.70</td><td>0.26, 1.9</td></tr><tr><td><i>Marital Status</i></td><td></td><td></td></tr><tr><td> Single</td><td>1.0</td><td></td></tr><tr><td> Married</td><td>2.5</td><td>0.74, 8.8</td></tr><tr><td><i>Believe mosquito nets that you have to buy are better quality (more effective in preventing malaria) than nets that are given out for free</i></td><td></td><td></td></tr><tr><td> No</td><td>1.0</td><td></td></tr><tr><td> Yes</td><td>0.36*</td><td>0.15, 0.88</td></tr><tr><td><i>Believe children suffer from malaria more than adults</i></td><td></td><td></td></tr><tr><td> No</td><td>1.0</td><td></td></tr><tr><td> Yes</td><td>0.49</td><td>0.22, 1.1</td></tr><tr><td><i>Think mosquito nets are difficult to use</i></td><td></td><td></td></tr><tr><td> No</td><td>1.0</td><td></td></tr><tr><td> Yes</td><td>0.19</td><td>0.034, 1.0</td></tr></table>
9ecaf4b514336d3725723310fe0e11659980e9698582dcc670fc099cf9593784.png
complex
<table><tr><td>Characteristics</td><td><i>KRAS</i> WT<i>N</i> (%)</td><td><i>KRAS</i> MUT<i>N</i> (%)</td><td><i>P&#8208;</i>value<i>KRAS</i> status</td><td>PTEN negative<i>N</i> (%)</td><td>PTEN positive<i>N</i> (%)</td><td><i>P</i>&#8208;valuePTEN status</td></tr><tr><td>All</td><td>48 (64)</td><td>27 (36)</td><td></td><td>56 (75)</td><td>19 (25)</td><td></td></tr><tr><td colspan="7">Sex</td></tr><tr><td>Female</td><td>17 (63)</td><td>10 (37)</td><td rowspan="2">1.000</td><td>17 (63)</td><td>10 (37)</td><td rowspan="2">0.141</td></tr><tr><td>Male</td><td>31 (65)</td><td>17 (35)</td><td>39 (81)</td><td>9 (19)</td></tr><tr><td colspan="7">Primary tumor</td></tr><tr><td>Colon</td><td>32 (71)</td><td>13 (29)</td><td rowspan="2">0.185</td><td>34 (76)</td><td>11 (24)</td><td rowspan="2">1.000</td></tr><tr><td>Rectum</td><td>16 (53)</td><td>14 (47)</td><td>22 (73)</td><td>8 (27)</td></tr><tr><td colspan="7">Lung metastases</td></tr><tr><td>Synchronous</td><td>12 (67)</td><td>6 (33)</td><td rowspan="2">1.000</td><td>15 (83)</td><td>3 (17)</td><td rowspan="2">0.368</td></tr><tr><td>Metachronous</td><td>35 (64)</td><td>20 (36)</td><td>39 (71)</td><td>16 (29)</td></tr><tr><td colspan="7">Localization</td></tr><tr><td>Unilateral</td><td>39 (65)</td><td>21 (35)</td><td rowspan="2">0.718</td><td>45 (75)</td><td>15 (25)</td><td rowspan="2">1.000</td></tr><tr><td>Bilateral</td><td>9 (60)</td><td>6 (40)</td><td>11 (73)</td><td>4 (27)</td></tr><tr><td colspan="7">Chemotherapy prior to lung surgery</td></tr><tr><td>Yes</td><td>22 (55)</td><td>18 (45)</td><td rowspan="2">0.135</td><td>34 (85)</td><td>6 (15)</td><td rowspan="2">0.053</td></tr><tr><td>No</td><td>26 (74)</td><td>9 (26)</td><td>22 (63)</td><td>13 (37)</td></tr><tr><td colspan="7">Adjuvant chemotherapy</td></tr><tr><td>No</td><td>41 (66)</td><td>21 (34)</td><td rowspan="2">1.000</td><td>45 (73)</td><td>17 (27)</td><td rowspan="2">1.000</td></tr><tr><td>Yes</td><td>5 (62)</td><td>3 (38)</td><td>6 (75)</td><td>2 (25)</td></tr><tr><td colspan="7">Extrapulmonary metastases</td></tr><tr><td>Yes</td><td>41 (68)</td><td>19 (32)</td><td rowspan="2">0.207</td><td>44 (73)</td><td>16 (27)</td><td rowspan="2">0.745</td></tr><tr><td>No</td><td>7 (47)</td><td>8 (53)</td><td>12 (80)</td><td>3 (20)</td></tr><tr><td colspan="7">Nodal involvement</td></tr><tr><td>Yes</td><td>27 (60)</td><td>18 (40)</td><td rowspan="2">0.308</td><td>33 (73)</td><td>12 (27)</td><td rowspan="2">0.550</td></tr><tr><td>No</td><td>16 (72)</td><td>6 (28%)</td><td>18 (82)</td><td>4 (18)</td></tr></table>
ab00e4a99d872770d9f83078f9e3f81623d1caa4ea39a830ab5627193e228f82.png
simple
<table><tr><td></td><td>Baseline</td><td>6 months after RDN</td><td><i>p</i> value</td></tr><tr><td>Office systolic blood pressure (mmHg)</td><td>180.4 &#177; 6.79</td><td>164.8 &#177; 8.06</td><td>0.01</td></tr><tr><td>Office diastolic blood pressure (mmHg)</td><td>94.88 &#177; 4.72</td><td>87.88 &#177; 3.63</td><td>0.04</td></tr><tr><td>Daytime ABPM systolic (mmHg)</td><td>158.3 &#177; 4.72</td><td>154.4 &#177; 5.53</td><td>0.49</td></tr><tr><td>Daytime ABPM diastolic (mmHg)</td><td>89.43 &#177; 2.84</td><td>88.29 &#177; 4.32</td><td>0.74</td></tr><tr><td>Nighttime ABPM systolic (mmHg)</td><td>151.3 &#177; 5.78</td><td>138.1 &#177; 8.00</td><td>0.06</td></tr><tr><td>Nighttime ABPM diastolic (mmHg)</td><td>83.71 &#177; 2.80</td><td>75.57 &#177; 4.64</td><td>0.03</td></tr></table>
7f2dc27fed3779ffe380d03a9f30154e5de2565c40f52b12ac7eb6657011075c.png
simple
<table><tr><td>Primer</td><td>Sequence (5&#8242;-3&#8242;)</td></tr><tr><td>F3</td><td>CTCGTGTCGTGAGATGTTG</td></tr><tr><td>B3</td><td>GAACGTATTCACCGTGGC</td></tr><tr><td>FIP</td><td>CCCACTCCATAAGGGCCATGAGGGACTTTAAGGAAACTGCC</td></tr><tr><td>BIP</td><td>CAATGGTGGCTACAATGGGCTGGCAGAGTACAATCCGAACTG</td></tr><tr><td>LoopF</td><td>CCACCTTCCTCCAGTTTATCAC</td></tr><tr><td>LoopB</td><td>CGCGAGGCTAAGCTAATCC</td></tr></table>
2ba134c825aa65971362ece80cb70b34cbcf66f97a3af347695e2930365e6a3a.png
complex
<table><tr><td colspan="3">History of visit n (%)</td></tr><tr><td>Sex</td><td>Male</td><td>11,028 (60)</td></tr><tr><td></td><td>Female</td><td>7,515 (40)</td></tr><tr><td>Age</td><td>18-30</td><td>5,181 (27.9)</td></tr><tr><td></td><td>31-45</td><td>6,752 (36.3)</td></tr><tr><td></td><td>46-60</td><td>4,949 (26.6)</td></tr><tr><td></td><td>61-75</td><td>1,336 (7.2)</td></tr><tr><td></td><td>75-90</td><td>360 (1.9)</td></tr><tr><td>Mode of arrival at EDs</td><td>Ambulance</td><td>585 (2.9)</td></tr><tr><td></td><td>Non-ambulance</td><td>18,150 (91.9)</td></tr><tr><td>Hospital</td><td>Public</td><td>19,164 (97.0)</td></tr><tr><td></td><td>Private</td><td>588 (3.0)</td></tr><tr><td>Treated for chest pain in last 72 hours</td><td>Male</td><td>1,888 (54.4)</td></tr><tr><td></td><td>Female</td><td>1,546 (44.5)</td></tr><tr><td>Episode of care</td><td>First visit</td><td>16,532 (83.7)</td></tr><tr><td></td><td>Follow-up visit</td><td>643 (3.2)</td></tr><tr><td></td><td>Don't know</td><td>85 (0.4)</td></tr><tr><td>Number of ED visits within last 12 months</td><td>0</td><td>6,072 (30.7)</td></tr><tr><td></td><td>1</td><td>3,750 (18.9)</td></tr><tr><td></td><td>2</td><td>1,198 (6)</td></tr><tr><td></td><td>3</td><td>540 (2.7)</td></tr><tr><td></td><td>4-10</td><td>518 (2.6)</td></tr><tr><td></td><td>Don't know</td><td>173 (0.9)</td></tr></table>
2f2320d7ceac68e812042f0adbd057fa50b78275ea6082bb7099a677965c0c94.png
simple
<table><tr><td></td><td>Original CE scale</td><td>New CE scale</td><td>New CE scale&#8212;social cohesion subscale</td><td>New CE scale&#8212; informal social control subscale</td></tr><tr><td>Disorder</td><td>&#8722;0.39</td><td>&#8722;0.33</td><td>&#8722;0.28</td><td>&#8722;0.33</td></tr><tr><td>Exchange</td><td>0.43</td><td>0.53</td><td>0.52</td><td>0.41</td></tr></table>
816e1e2b30df78817d3a14f499e48d8fca56c770eceb8aa66254e3a884a1ebb3.png
complex
<table><tr><td rowspan="2">Research question</td><td rowspan="2">Outcome</td><td rowspan="2">Method of analysis</td><td colspan="2">Results from the model data set</td></tr><tr><td>All respondents, n = 244</td><td>Highly compliant respondents, answering 80% (&#8805;15/18 weeks), n = 161</td></tr><tr><td>4A: Association of baseline variables with outcome</td><td>Weekly recorded pain days, count variable, assuming a binominal distribution</td><td>Multilevel mixed-effects logistic regression or generalized estimating equation assuming a logit link function (Long previous duration reference category)</td><td>Subject specific OR = 3.31 (95% CI: 2.1-5.1) Population average OR = 1.96 (95% CI 1.4-2.6) (Note: Interaction duration*week significant)</td><td>Subject specific OR = 2.67 (95% CI: 1.6-4.5) Population average OR =1.52 (95% CI 1.1- 2.2) (Note: Interaction duration*week significant)</td></tr><tr><td>4B: Association of baseline variables with outcome</td><td>Weekly recorded pain days, count variable, assuming a Poisson distribution</td><td>Multilevel mixed-effects Poisson regression assuming a log link function (Long previous duration reference category)</td><td>Subject specific IRR = 1.92 (95% CI: 1.5 &#8211; 2.4) (Note: Interaction duration*week significant)</td><td>Subject specific IRR = 1.82 (95% CI: 1.4 &#8211; 2.4) (Note: Interaction duration*week significant)</td></tr><tr><td>4 C: Association of baseline variables with outcome</td><td>Weekly recorded pain days, considered a count variable and assuming a normal distribution</td><td>Generalized linear regression or mixed linear model assuming an identity link function</td><td>Average difference in pain days for Long duration &#8211; Short duration 1.20 (95% CI: 0.8 &#8211; 1.5) (Note: Interaction duration*week significant)</td><td>Average difference in pain days for Long duration &#8211;Short duration 0.95 (95% CI: 0.6-1.4) Note: Interaction duration*week significant)</td></tr></table>
cdfd170d03e97e6d112e2d6820de18735b75ddc1dc00cad49c98313be10df14b.png
simple
<table><tr><td>Antibody</td><td>Species</td><td>Epitope</td><td>Dilution</td></tr><tr><td>Santa Cruz #sc-1751</td><td>Goat polyclonal (clone C-20)</td><td>near C-terminus</td><td>1:300</td></tr><tr><td>Santa Cruz #sc-48371</td><td>Mouse monoclonal (clone D-9)</td><td>aa 21-140 (near N-terminus)</td><td>1:200</td></tr><tr><td>Santa Cruz #sc-28237</td><td>Rabbit polyclonal (clone H-120)</td><td>aa 21-140 (near N-terminus)</td><td>1:300</td></tr><tr><td>Abcam #ab140595</td><td>Rabbit monoclonal</td><td>aa 350 to the C-terminus</td><td>1:100</td></tr><tr><td>Abcam #ab40693</td><td>Rabbit polyclonal</td><td>aa 350 to the C-terminus</td><td>1:500</td></tr><tr><td>ProteinTech #12133-2-AP</td><td>Rabbit polyclonal</td><td>human TIA1-GST fusion protein</td><td>1:100</td></tr></table>
1e5dfe007c4dfb5b480868a277937629d689e5dcdf587609e82c9246abb9e1c8.png
simple
<table><tr><td>Response*</td><td>Percent (n = 83)</td></tr><tr><td>I managed the patient myself</td><td>34</td></tr><tr><td>The patient improved while waiting to be seen</td><td>29</td></tr><tr><td>I referred to a pediatric infectious disease specialist instead</td><td>28</td></tr><tr><td>I referred to adult rheumatologist instead</td><td>20</td></tr><tr><td>I referred to a pediatric orthopedist instead</td><td>12</td></tr><tr><td>I referred to a pediatric hematology/oncology specialist instead</td><td>9</td></tr><tr><td>Other</td><td>9</td></tr><tr><td>The distance or time to travel was too long</td><td>8</td></tr><tr><td>I referred to a pediatric sports medicine specialist instead</td><td>4</td></tr><tr><td>I referred to a general orthopedist instead</td><td>4</td></tr><tr><td>The patient&#8217;s insurance would not cover a PR referral</td><td>1</td></tr></table>
15eba3571d9c6d2c0bd2472beb53b1c97a3b86a5a80373463165d6d3e72b52d5.png
complex
<table><tr><td></td><td>HC 1 (%)</td><td>HC 2 (%)</td></tr><tr><td colspan="3">Frequency of product consumption</td></tr><tr><td>More than once per day</td><td>42</td><td>46</td></tr><tr><td>Once per day</td><td>58</td><td>54</td></tr><tr><td colspan="3">Amount of product given per day</td></tr><tr><td>&lt;1 sachet</td><td>18</td><td>4</td></tr><tr><td>1 sachet</td><td>80</td><td>96</td></tr><tr><td>&gt;1 sachet</td><td>2</td><td>0</td></tr><tr><td colspan="3">Child took product as instructed</td></tr><tr><td>Yes, always or most of time</td><td>83</td><td>85</td></tr><tr><td>Yes, about half the time</td><td>7</td><td>0</td></tr><tr><td>No, usually not</td><td>11</td><td>8</td></tr><tr><td>No response</td><td>1</td><td>2</td></tr></table>
4432a3ca8de6cacc4f3133a41d3d7b4e1994653aebfabfadf8e59dd3a55c3a66.png
simple
<table><tr><td>Variables</td><td>Subgroup</td><td><i>N</i></td><td>Mean rank</td><td>Sum rank</td><td>U</td><td><i>p</i></td></tr><tr><td>Lymphovascular invasion</td><td>No</td><td>85</td><td>69.88</td><td>5939.50</td><td>1285.500</td><td>0.010</td></tr><tr><td></td><td>Yes</td><td>42</td><td>52.11</td><td>2188.50</td><td></td><td></td></tr><tr><td><i>PIK3CA</i> gene mutation</td><td>Wild type</td><td>120</td><td>62.23</td><td>7467.00</td><td>207.000</td><td>0.024</td></tr><tr><td></td><td>Mutation</td><td>7</td><td>94.43</td><td>661.00</td><td></td><td></td></tr></table>
66e61adb6a35118804895d19917efcaa80a3268bba3e93e1e53226c95864aed9.png
simple
<table><tr><td></td><td>All States</td><td>NH</td><td>ME</td><td>VT</td></tr><tr><td>Total Population</td><td>3,119,527</td><td>1,235,791</td><td>1,274,915</td><td>608,821</td></tr><tr><td>Psychiatric Admissions</td><td>22,503</td><td>6,842</td><td>12,319</td><td>3,342</td></tr><tr><td>Percent Female</td><td>53%</td><td>56%</td><td>51%</td><td>57%</td></tr><tr><td>Length of Stay (days)</td><td></td><td></td><td></td><td></td></tr><tr><td> Mean (SD)</td><td>8.97 (11.83)</td><td>8.22 (10.12)</td><td>9.6 (13.81)</td><td>8.17 (9.42)</td></tr><tr><td> Median</td><td>6</td><td>6</td><td>7</td><td>6</td></tr><tr><td> Range</td><td>1-297</td><td>1-297</td><td>1-252</td><td>1-128</td></tr><tr><td>Diagnosis</td><td></td><td></td><td></td><td></td></tr><tr><td> Psychosis</td><td>47%</td><td>47%</td><td>45%</td><td>55%</td></tr><tr><td> Substance Use Disorder</td><td>23%</td><td>22%</td><td>28%</td><td>11%</td></tr><tr><td> Neurosis</td><td>12%</td><td>11%</td><td>10%</td><td>16%</td></tr><tr><td> Detoxification</td><td>5%</td><td>4%</td><td>5%</td><td>2%</td></tr><tr><td> Organic Disorder</td><td>5%</td><td>7%</td><td>4%</td><td>5%</td></tr><tr><td> Adjustment Disorder</td><td>4%</td><td>3%</td><td>3%</td><td>6%</td></tr><tr><td> Personality Disorder</td><td>2%</td><td>3%</td><td>1%</td><td>4%</td></tr><tr><td> Other</td><td>3%</td><td>1%</td><td>4%</td><td>1%</td></tr><tr><td>Age</td><td></td><td></td><td></td><td></td></tr><tr><td> 18-24</td><td>14%</td><td>12%</td><td>15%</td><td>13%</td></tr><tr><td> 25-44</td><td>48%</td><td>47%</td><td>48%</td><td>49%</td></tr><tr><td> 45-64</td><td>22%</td><td>22%</td><td>20%</td><td>22%</td></tr><tr><td> 65-74</td><td>7%</td><td>7%</td><td>7%</td><td>6%</td></tr><tr><td> &gt; 75</td><td>11%</td><td>12%</td><td>10%</td><td>10%</td></tr></table>
d8515d5bc2c8d3f61304d7289ac7ac892ab3046953250e73de926bc813077b37.png
complex
<table><tr><td>Diagnosis</td><td>No.</td><td>M:F ratio</td><td>Median age (Range)</td><td colspan="3">Diagnostic category</td><td>Blind in at least one eye (%)</td><td>Previously diagnosed (%)</td></tr><tr><td></td><td></td><td></td><td></td><td>1</td><td>2</td><td>3</td><td></td><td></td></tr><tr><td>POAG with normal IOP</td><td>50</td><td>26:24</td><td>63 (53&#8211;99)</td><td>36</td><td>14</td><td>0</td><td>4 (8)</td><td>2 (4)</td></tr><tr><td>POAG with high IOP</td><td>22</td><td>11:11</td><td>66 (51&#8211;86)</td><td>13</td><td>5</td><td>4</td><td>5 (22.73)</td><td>6 (27.27)</td></tr><tr><td>Total POAG</td><td>72</td><td>37:35</td><td>65 (51&#8211;99)</td><td>49</td><td>19</td><td>4</td><td>9 (12.5)</td><td>8 (11.11)</td></tr></table>
63fe986bb4efff477e3e9f99da146a84ba085977fd1709b5b13a6a6788c68371.png
complex
<table><tr><td rowspan="2">Group</td><td colspan="2">Thickness</td><td colspan="2">Buckling value, &#956;m</td></tr><tr><td><i>d<sub>s</sub></i>, &#956;m</td><td><i>d<sub>b</sub></i>, &#956;m</td><td>Experiment</td><td>Model</td></tr><tr><td>2</td><td>42</td><td>83</td><td>1.55</td><td>1.59</td></tr><tr><td>3</td><td>42</td><td>97</td><td>1.31</td><td>1.42</td></tr><tr><td>4</td><td>31</td><td>83</td><td>0.90</td><td>1.03</td></tr></table>
67e048096790514a653b2d06096815a0ec27986605765b767f60b29a8284416b.png
complex
<table><tr><td>Cells</td><td>Stimulus</td><td>Effect</td><td>Reference</td></tr><tr><td rowspan="2">Alveolar macrophages</td><td rowspan="2">LPS</td><td>&#8595; inflammatory cytokines</td><td>Baldwin et al. [16]</td></tr><tr><td> </td><td>Pacifici et al. [17]</td></tr><tr><td rowspan="2">Monocytes</td><td rowspan="2">LPS</td><td>&#8595; inflammatory cytokines</td><td>Zurier et al. [95]</td></tr><tr><td>Impairs differentiation to dendritic cells</td><td>Roth et al. [122]</td></tr><tr><td rowspan="5">Thioglycollate-elicited macrophages</td><td rowspan="2"> LPS</td><td>&#8595; tumor necrosis factor-<i>&#945;</i> protein processing</td><td> Zheng and Specter [99]</td></tr><tr><td>&#8593; interleukin-1<i>&#946;</i></td><td>Zhu et al. [94]</td></tr><tr><td rowspan="3">LPS/interferon-<i>&#947;</i></td><td>&#8595; nitric oxide synthase-2</td><td>Coffey et al. [102]</td></tr><tr><td>&#8595; nitric oxide</td><td>Mestre et al. [92]</td></tr><tr><td>&#8593; interleukin-10</td><td>Correa et al. [109]</td></tr><tr><td rowspan="2">Blood mononuclear cells</td><td rowspan="2">LPS</td><td>&#8595; interleukin-1<i>&#945;</i></td><td>Watzl et al. [96]</td></tr><tr><td>Biphasic dose-response</td><td>Berdyshev et al. [97]</td></tr><tr><td rowspan="5">Microglial cells</td><td rowspan="3">LPS</td><td>&#8595; cytokine mRNA</td><td>Puffenbarger et al. [103]</td></tr><tr><td>&#8593; IL-1 receptor antagonist</td><td>Molina-Holgado et al. [111]</td></tr><tr><td>&#8595; nitric oxide</td><td>Merighi et al. [123]</td></tr><tr><td rowspan="2">LPS/interferon-<i>&#947;</i></td><td>&#8593; interleukin-10</td><td>Correa et al. [110]</td></tr><tr><td>&#8595; nitric oxide</td><td>Waksman et al. [124]</td></tr><tr><td>Dendritic cells</td><td>LPS</td><td>&#8595; TLR4 expression</td><td>Xu et al. [106]</td></tr><tr><td rowspan="3">BV-2 cells</td><td rowspan="3">LPS</td><td>&#8595; NF-<i>&#954;</i>B activity</td><td>More et al. [101]</td></tr><tr><td>&#8595; cytokine mRNA</td><td> </td></tr><tr><td>&#8595; interferon-<i>&#946;</i> mRNA</td><td>Kozela et al. [125]</td></tr><tr><td rowspan="3">J774 cells</td><td rowspan="3">LPS</td><td>&#8595; nitric oxide</td><td>Chang et al. [93]</td></tr><tr><td>&#8595; interleukin-6</td><td> </td></tr><tr><td>&#8595; cyclooxygenase-2</td><td> </td></tr><tr><td rowspan="4">RAW 264.7 cells</td><td rowspan="4">LPS</td><td>&#8595; tumor necrosis factor-<i>&#945;</i> protein processing</td><td>Fischer-Stenger et al. [100]</td></tr><tr><td>&#8595; nitric oxide synthase-2</td><td>Jeon et al. [104]</td></tr><tr><td>&#8595; nitric oxide</td><td> </td></tr><tr><td>&#8595; NF-<i>&#954;</i>B activity</td><td> </td></tr><tr><td rowspan="2">TLR4-transfected HEK293 cells</td><td rowspan="2">LPS</td><td>&#8595; interferon-<i>&#946;</i> mRNA</td><td>Downer et al. [126]</td></tr><tr><td>&#8595; IRF3 activity</td><td> </td></tr><tr><td>Glioma U87MG cells</td><td>Peptidoglycan</td><td>&#8595; NF-<i>&#954;</i>B activity</td><td>Echigo et al. [105]</td></tr><tr><td rowspan="4">TLR3-transfected HEK293 cells</td><td rowspan="4">Polyinosinic:polycytidylic acid</td><td>&#8593; interferon-<i>&#946;</i> mRNA</td><td>Downer et al. [127]</td></tr><tr><td>&#8593; IRF3 activity</td><td>Downer et al. [126]</td></tr><tr><td>&#8595; tumor necrosis factor-<i>&#945;</i></td><td> </td></tr><tr><td>&#8595; NF-<i>&#954;</i>B activity</td><td> </td></tr><tr><td rowspan="2">Blood mononuclear cells</td><td rowspan="2">Polyinosinic:polycytidylic acid</td><td>&#8593; interferon-<i>&#946;</i> mRNA</td><td>Downer et al. [126]</td></tr><tr><td>&#8595; tumor necrosis factor-<i>&#945;</i></td><td> </td></tr></table>
21e9716e509bc38aa3ed0894e80ac634c3c3cdc537c48a759f8d1874b8918c90.png
complex
<table><tr><td>DATASET</td><td>ALL</td><td>GA-FS</td><td>H-MTL</td><td>GA-MTL</td><td>GA-MTL-IR</td><td>e-GA-MTL</td></tr><tr><td colspan="7"><i>M</i> = 2 for ANN</td></tr><tr><td>Breast</td><td>53.0(9.9)</td><td>58.8(8.6)</td><td>52.9(9.0)</td><td>70.7(8.7)</td><td>64.7(9.2)</td><td>64.8(9.2)</td></tr><tr><td>Colon</td><td>71.3(10.2)</td><td>64.7(9.5)</td><td>73.4(8.4)</td><td>85.7(9.8)</td><td>85.7(9.1)</td><td>85.7(8.4)</td></tr><tr><td>Leukemia</td><td>55.6(7.5)</td><td>44.4(8.3)</td><td>55.4(8.1)</td><td>71.7(7.8)</td><td>77.8(7.5)</td><td>83.3(7.4)</td></tr><tr><td>Ovarian</td><td>55.6(6.1)</td><td>64.9(6.2)</td><td>74.4(6.1)</td><td>77.7(7.6)</td><td>79.7(7.3)</td><td>81.5(7.0)</td></tr><tr><td>Average</td><td>58.5(8.4)</td><td>58.6(8.1)</td><td>64.3(8.0)</td><td>76.1(8.4)</td><td>76.3(8.2)</td><td>78.8(8.0)</td></tr><tr><td colspan="7"><i>M</i> = 10 for ANN</td></tr><tr><td>Breast</td><td>48.1(8.8)</td><td>55.4(8.4)</td><td>65.1(8.0)</td><td>69.2(8.1)</td><td>63.9(9.6)</td><td>66.8(8.4)</td></tr><tr><td>Colon</td><td>71.3(10.0)</td><td>85.3(9.7)</td><td>83.5(10.5)</td><td>92.2(9.7)</td><td>93.1(10.0)</td><td>92.6(10.8)</td></tr><tr><td>Leukemia</td><td>65.4(8.5)</td><td>77.4(7.8)</td><td>75.6(8.1)</td><td>64.8(6.8)</td><td>78.4(6.2)</td><td>91.5(6.0)</td></tr><tr><td>Ovarian</td><td>61.3(5.1)</td><td>65.6(5.9)</td><td>77.0(4.3)</td><td>79.4(5.0)</td><td>87.0(5.4)</td><td>80.4(5.5)</td></tr><tr><td>Average</td><td>61.0(8.1)</td><td>71.8(8.1)</td><td>75.8(7.6)</td><td>78.1(7.9)</td><td>82.2(7.8)</td><td>82.6(7.6)</td></tr></table>
b43ae3a9ab555821356f403c10115f52d9e6e2eca7827142999989ce68b9f31a.png
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<table><tr><td> </td><td>N, n</td><td>Mean performance score</td><td>SD</td><td>F-test, p-value</td></tr><tr><td><i>Location</i></td><td><i>67</i></td><td><i>-</i></td><td><i>-</i></td><td><i>0.028*</i></td></tr><tr><td> National government hospital 1</td><td>16</td><td>32.6</td><td>11.0</td><td> </td></tr><tr><td> Regional government hospital 2</td><td>17</td><td>22.5</td><td>8.1</td><td> </td></tr><tr><td> Regional government hospital 3</td><td>15</td><td>27.4</td><td>10.6</td><td> </td></tr><tr><td> District government hospital 4</td><td>12</td><td>26.8</td><td>9.6</td><td> </td></tr><tr><td> District private non-profit hospital 5</td><td>7</td><td>21.3</td><td>6.1</td><td> </td></tr><tr><td><i>Type of near-miss complication</i></td><td><i>67</i></td><td><i>-</i></td><td><i>-</i></td><td><i>0.7*</i></td></tr><tr><td> NM haemorrhage</td><td>28</td><td>27.0</td><td>11.8</td><td> </td></tr><tr><td> NM hypertensive disorder</td><td>17</td><td>25.9</td><td>9.9</td><td> </td></tr><tr><td> NM obstructed labour</td><td>13</td><td>28.1</td><td>9.2</td><td> </td></tr><tr><td> NM infection/sepsis</td><td>6</td><td>27.7</td><td>5.6</td><td> </td></tr><tr><td> NM anaemia</td><td>3</td><td>18.8</td><td>4.4</td><td> </td></tr><tr><td><i>Project maturity</i></td><td><i>67</i></td><td><i>-</i></td><td><i>-</i></td><td><i>0.5*</i></td></tr><tr><td> First half of audits</td><td>33</td><td>27.5</td><td>10.2</td><td> </td></tr><tr><td> Second half of audits</td><td>34</td><td>25.9</td><td>10.1</td><td> </td></tr><tr><td><i>Moderation of audit team</i></td><td><i>50</i><sup><i>#</i></sup></td><td><i>-</i></td><td><i>-</i></td><td><i>0.030*</i></td></tr><tr><td> by a midwife</td><td>24</td><td>23.4</td><td>9.1</td><td> </td></tr><tr><td> by a physician</td><td>26</td><td>29.7</td><td>10.7</td><td> </td></tr></table>
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<table><tr><td>Use categories</td><td>No. of taxa</td><td>No. of use reports</td><td>Consensus factor</td></tr><tr><td>Stomach disorder (diarrhoea/dysentry)</td><td>8</td><td>178</td><td>0.96</td></tr><tr><td>Cuts and wounds</td><td>4</td><td>160</td><td>0.98</td></tr><tr><td>Fever and headache</td><td>6</td><td>125</td><td>0.96</td></tr><tr><td>Skin diseases/skin irritation</td><td>2</td><td>4</td><td>0.67</td></tr><tr><td>Worms in stomach</td><td>2</td><td>120</td><td>0.99</td></tr><tr><td>Nausea and vomiting</td><td>2</td><td>73</td><td>0.98</td></tr><tr><td>Snake and scorpion bites</td><td>2</td><td>8</td><td>0.85</td></tr><tr><td>Cough and cold</td><td>4</td><td>186</td><td>0.98</td></tr></table>
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<table><tr><td>Category</td><td>Males</td><td>Females</td><td>Total</td></tr><tr><td>People living with HIV</td><td>9</td><td>14</td><td>23</td></tr><tr><td> Intervention</td><td>5</td><td>10</td><td>15</td></tr><tr><td> Control</td><td>4</td><td>4</td><td>8</td></tr><tr><td>Peer Supporters</td><td>3</td><td>6</td><td>9</td></tr><tr><td>Program staff</td><td>3</td><td>4</td><td>7</td></tr><tr><td>Total</td><td>15</td><td>24</td><td>39</td></tr></table>
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<table><tr><td>Study population characteristic</td><td>HCV Prevalence (%)</td><td>Unadjusted OR (95 % CI)</td><td>Adjusted OR (95 % CI)<sup>a</sup></td></tr><tr><td>Overall</td><td>29.8</td><td>NA</td><td>NA</td></tr><tr><td>Gender</td><td></td><td></td><td></td></tr><tr><td> Male</td><td>32.2</td><td>Ref</td><td>Ref</td></tr><tr><td> Female</td><td>25.3</td><td>0.71 (0.56, 0.91)</td><td>0.65 (0.48, 0.86)</td></tr><tr><td>Age group</td><td></td><td></td><td></td></tr><tr><td> 1913&#8211;1939</td><td>40.5</td><td>Ref.</td><td>Ref</td></tr><tr><td> 1940&#8211;1949</td><td>45.0</td><td>1.20 (0.79, 1.82)</td><td>1.32 (0.85, 2.04)</td></tr><tr><td> 1950&#8211;1959</td><td>42.1</td><td>1.07 (0.73, 1.57)</td><td>1.17 (0.78, 1.76)</td></tr><tr><td> 1960&#8211;1969</td><td>27.2</td><td>0.55 (0.36, 0.83)</td><td>0.59 (0.38, 0.91)</td></tr><tr><td> 1970&#8211;1979</td><td>15.0</td><td>0.26 (0.16, 0.43)</td><td>0.27 (0.16, 0.45)</td></tr><tr><td> 1980+</td><td>6.8</td><td>0.11 (0.06, 0.19)</td><td>0.10 (0.06, 0.20)</td></tr><tr><td>Education</td><td></td><td></td><td></td></tr><tr><td> No schooling, literacy only, or religious school</td><td>35.5</td><td>Ref.</td><td>Ref.</td></tr><tr><td> Primary through secondary</td><td>27.6</td><td>0.69 (0.54, 0.88)</td><td>1.21 (0.91, 1.61)</td></tr><tr><td> Higher education</td><td>21.8</td><td>0.55 (0.46, 0.66)</td><td>0.90 (0.51, 1.59)</td></tr><tr><td>Migration pattern</td><td></td><td></td><td></td></tr><tr><td> Current same as birth &#8211; rural</td><td>35.1</td><td>Ref.</td><td>Ref.</td></tr><tr><td> Current same as birth - urban</td><td>15.7</td><td>0.34 (0.18, 0.66)</td><td>0.41 (0.20, 0.84)</td></tr><tr><td> Urban to urban migration</td><td>17.7</td><td>0.40 (0.27, 0.58)</td><td>0.32 (0.21, 0.50)</td></tr><tr><td> Rural to rural migration</td><td>41.2</td><td>1.30 (0.92, 1.82)</td><td>1.03 (0.70, 1.51)</td></tr><tr><td> Rural to urban migration</td><td>32.2</td><td>0.88 (0.59, 1.3)</td><td>0.64 (0.41, 0.99)</td></tr><tr><td> Urban to rural migration</td><td>12.3</td><td>0.26 (0.12, 0.57)</td><td>0.21 (0.09, 0.48)</td></tr><tr><td>Birthplace</td><td></td><td></td><td></td></tr><tr><td> Urban</td><td>16.7</td><td>Ref.</td><td>Ref.</td></tr><tr><td> Rural</td><td>37.5</td><td>3.00 (2.30, 3.91)</td><td>2.36 (1.68, 3.31)<sup>b</sup></td></tr><tr><td>Residence at time of interview</td><td></td><td></td><td></td></tr><tr><td> Urban</td><td>22.2</td><td>Ref.</td><td>Ref.</td></tr><tr><td> Rural</td><td>36.9</td><td>2.04 (1.62, 2.57)</td><td>1.35 (1.01, 1.83)<sup>b</sup></td></tr></table>
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<table><tr><td rowspan="2">Attribute</td><td colspan="2">Total Assessment Score for Pa&#770;te&#769; Made From</td><td rowspan="2"><i>p</i> Value</td><td rowspan="2">SEM <sup>a</sup></td></tr><tr><td>Fresh Livers</td><td>Frozen Livers</td></tr><tr><td>Color on surface</td><td>70.5</td><td>67.1</td><td>0.29</td><td>3.25</td></tr><tr><td>Color inside</td><td>28.7</td><td>47.6</td><td>&lt;0.001</td><td>3.20</td></tr><tr><td>Color likeability</td><td>38.6</td><td>40.4</td><td>0.63</td><td>3.62</td></tr><tr><td>Texture on cutting</td><td>29.9</td><td>30.9</td><td>0.8</td><td>3.63</td></tr><tr><td>On-eating firmness</td><td>41.3</td><td>22.1</td><td>&lt;0.001</td><td>4.43</td></tr><tr><td>On-eating dissolvability</td><td>73.9</td><td>75.1</td><td>0.72</td><td>3.31</td></tr><tr><td>Flavor strength</td><td>52.7</td><td>61.9</td><td>&lt;0.001</td><td>2.21</td></tr><tr><td>Fatty</td><td>39.0</td><td>37.6</td><td>0.62</td><td>2.65</td></tr><tr><td>Livery</td><td>40.4</td><td>41.0</td><td>0.84</td><td>2.68</td></tr><tr><td>Acidic</td><td>8.4</td><td>12.8</td><td>&lt;0.05</td><td>1.93</td></tr><tr><td>Rancid</td><td>3.6</td><td>4.2</td><td>0.45</td><td>0.69</td></tr><tr><td>Sweet</td><td>30.6</td><td>30.7</td><td>0.94</td><td>2.33</td></tr><tr><td>Peppery</td><td>21.3</td><td>22.3</td><td>0.7</td><td>2.63</td></tr><tr><td>Herby</td><td>29.9</td><td>33.1</td><td>0.2</td><td>2.55</td></tr><tr><td>Salty</td><td>22.2</td><td>22.8</td><td>0.71</td><td>1.49</td></tr><tr><td>Residue after eating</td><td>20.1</td><td>7.8</td><td>&lt;0.001</td><td>2.84</td></tr><tr><td>Flavor likeability</td><td>44.8</td><td>51.0</td><td>&lt;0.05</td><td>2.65</td></tr><tr><td>Overall likeability</td><td>36.0</td><td>48.6</td><td>&lt;0.001</td><td>3.05</td></tr></table>
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<table><tr><td rowspan="2">Vertical Anomalies</td><td colspan="2">Age 3 (Year)</td><td colspan="2">Age 4 (Year)</td><td colspan="2">Age 5 (Year)</td><td colspan="2">Total</td></tr><tr><td><i>n</i></td><td>%</td><td><i>n</i></td><td>%</td><td><i>n</i></td><td>%</td><td><i>n</i></td><td>%</td></tr><tr><td>Deep overbite</td><td>532</td><td>62.9</td><td>499</td><td>68.5</td><td>457</td><td>60.1</td><td>1488</td><td>63.7</td></tr><tr><td> Mild (&gt;1/2, &#8804;3/4)</td><td>204</td><td>24.1</td><td>172</td><td>23.6</td><td>144</td><td>18.9</td><td>520</td><td>22.3</td></tr><tr><td> Moderate (&gt;3/4, &lt;1)</td><td>202</td><td>23.9</td><td>224</td><td>30.8</td><td>185</td><td>24.3</td><td>611</td><td>26.2</td></tr><tr><td> Severe (all cover)</td><td>126</td><td>14.9</td><td>103</td><td>14.1</td><td>128</td><td>16.8</td><td>357</td><td>15.3</td></tr><tr><td>Open bite</td><td>5</td><td>0.6 </td><td>3</td><td>0.4</td><td>2</td><td>0.3</td><td>10</td><td>0.4</td></tr><tr><td> Moderate (&gt;3 mm, &#8804;5 mm)</td><td>4</td><td>0.5 </td><td>3</td><td>0.4</td><td>1</td><td>0.1</td><td>8</td><td>0.3</td></tr><tr><td> Severe (&gt;5 mm)</td><td>1</td><td>0.1 </td><td>0</td><td>0.0</td><td>1</td><td>0.1</td><td>2</td><td>0.1</td></tr></table>
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<table><tr><td></td><td>Overall (%)</td><td>Non-Hispanic White (%)</td><td>Non-Hispanic Black (%)</td><td>Hispanic (%)</td><td>Other (%)</td></tr><tr><td><i>N</i></td><td><i>1005</i></td><td><i>649</i></td><td><i>118</i></td><td><i>157</i></td><td><i>81</i></td></tr><tr><td colspan="6">During past 12 months, have you received a flu shot or vaccine?</td></tr><tr><td> Yes</td><td>42.3</td><td>45.4 <sup>a</sup></td><td>50.9 <sup>a</sup></td><td>20.8 <sup>b</sup></td><td>44.4 <sup>a</sup></td></tr><tr><td> No</td><td>57.7</td><td>54.6 <sup>a</sup></td><td>49.1 <sup>a</sup></td><td>79.2 <sup>b</sup></td><td>55.6 <sup>a</sup></td></tr><tr><td colspan="6">If yes, in which month did you receive your most recent flu vaccine?</td></tr><tr><td> September</td><td>27.7</td><td>27.6</td><td>33.3</td><td>27.6</td><td>20.0</td></tr><tr><td> October</td><td>40.8</td><td>43.8</td><td>33.3</td><td>27.6</td><td>40.0</td></tr><tr><td> November</td><td>18.2</td><td>16.9</td><td>14.8</td><td>27.6</td><td>28.6</td></tr><tr><td> December</td><td>2.6</td><td>3.4</td><td>1.9</td><td>0.0</td><td>0.0</td></tr><tr><td> January/February</td><td>4.3</td><td>3.1 <sup>a</sup></td><td>5.6 <sup>a</sup></td><td>13.8 <sup>b</sup></td><td>5.8 <sup>a</sup></td></tr><tr><td colspan="6">How likely are you to get a flu Vaccination this season (2016&#8211;2017)&#8212;that is, this Fall or Winter?</td></tr><tr><td> Already received</td><td>13.5</td><td>14.7 <sup>a,b</sup></td><td>19.3 <sup>b</sup></td><td>6.5 <sup>c</sup></td><td>8.8 <sup>a,c</sup></td></tr><tr><td> Will definitely get one</td><td>26.7</td><td>27.6 <sup>a</sup></td><td>31.1 <sup>a</sup></td><td>18.2 <sup>b</sup></td><td>27.5 <sup>a,b</sup></td></tr><tr><td> Will probably get one</td><td>13.8</td><td>12.0 <sup>a</sup></td><td>10.1 <sup>a</sup></td><td>18.8 <sup>b</sup></td><td>25.0 <sup>b</sup></td></tr><tr><td> Will probably not get one</td><td>18.9</td><td>20.8 <sup>a</sup></td><td>15.1 <sup>a,b</sup></td><td>19.5 <sup>a</sup></td><td>8.8 <sup>b</sup></td></tr><tr><td> Will definitely not get one</td><td>27.0</td><td>24.8 <sup>a</sup></td><td>24.4 <sup>a</sup></td><td>37.0 <sup>b</sup></td><td>30.0 <sup>a,b</sup></td></tr><tr><td colspan="6">Thinking about 2013, 2014, and 2015, in how many of those years did you get a flu vaccination?</td></tr><tr><td> Received in all three years</td><td>35.7</td><td>39.7 <sup>a</sup></td><td>37.9 <sup>a</sup></td><td>16.4 <sup>b</sup></td><td>33.8 <sup>a</sup></td></tr><tr><td> Received in two years</td><td>10.7</td><td>9.5</td><td>13.8</td><td>12.9</td><td>12.5</td></tr><tr><td> Received one year</td><td>12.5</td><td>11.0 <sup>a</sup></td><td>12.1 <sup>a,b</sup></td><td>19.3 <sup>b</sup></td><td>15.0 <sup>a,b</sup></td></tr><tr><td> None</td><td>41.1</td><td>39.7 <sup>a</sup></td><td>36.2 <sup>a</sup></td><td>51.4 <sup>b</sup></td><td>38.8 <sup>a,b</sup></td></tr><tr><td colspan="6">Have you ever delayed getting a recommended flu vaccination for reasons other than illness or allergy?</td></tr><tr><td> Yes</td><td>19.2</td><td>19.8</td><td>19.5</td><td>17.2</td><td>17.3</td></tr><tr><td colspan="6">Have you ever declined getting a recommended flu vaccination for reasons other than illness or allergy?</td></tr><tr><td> Yes</td><td>29.5</td><td>31.9 <sup>a</sup></td><td>18.6 <sup>b</sup></td><td>27.8 <sup>a,b</sup></td><td>29.6 <sup>a,b</sup></td></tr></table>
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<table><tr><td>Sample name</td><td>Raw reads</td><td>Clean reads</td><td>Q20 (%)</td><td>Q30 (%)</td><td>Total mapped (%)</td><td>Uniquely mapped (%)</td></tr><tr><td>V10_1</td><td>53,944,714</td><td>52,820,194</td><td>97.37</td><td>93.68</td><td>75.82</td><td>74.70</td></tr><tr><td>V10_2</td><td>59,160,706</td><td>57,378,292</td><td>97.39</td><td>93.81</td><td>76.44</td><td>75.46</td></tr><tr><td>V10_3</td><td>53,875,186</td><td>51,827,434</td><td>97.17</td><td>93.2</td><td>77.45</td><td>76.26</td></tr><tr><td>NC10_1</td><td>57,025,992</td><td>54,713,970</td><td>96.84</td><td>92.51</td><td>77.09</td><td>75.89</td></tr><tr><td>NC10_2</td><td>60,174,142</td><td>58,164,444</td><td>95.01</td><td>88.06</td><td>71.81</td><td>70.75</td></tr><tr><td>V18_1</td><td>58,591,660</td><td>56,688,518</td><td>95.1</td><td>88.24</td><td>72.40</td><td>71.34</td></tr><tr><td>V18_2</td><td>63,030,008</td><td>60,813,608</td><td>95.05</td><td>88.16</td><td>71.95</td><td>70.89</td></tr><tr><td>V18_3</td><td>44,002,734</td><td>42,770,420</td><td>96.75</td><td>92.22</td><td>73.96</td><td>72.89</td></tr><tr><td>NC18_1</td><td>51,089,720</td><td>48,895,588</td><td>96.24</td><td>91.26</td><td>74.02</td><td>72.96</td></tr><tr><td>NC18_2</td><td>61,366,046</td><td>59,972,578</td><td>97.11</td><td>93.2</td><td>75.05</td><td>73.90</td></tr><tr><td>NC18_3</td><td>68,023,822</td><td>65,597,914</td><td>97.36</td><td>93.79</td><td>76.15</td><td>75</td></tr></table>
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<table><tr><td>Name </td><td>Amount [mg/100g Star-fruit weight]*</td></tr><tr><td>Carotene</td><td>0.003 - 0.55</td></tr><tr><td>Tartaric acid</td><td>4.37</td></tr><tr><td>Oxalic acid</td><td>9.6</td></tr><tr><td>Ketoglutaric acid</td><td>2.2</td></tr><tr><td>Citric acid</td><td>1.32</td></tr><tr><td>Vitamin B1 &amp; B2</td><td>0.12</td></tr><tr><td>Vitamin C</td><td>25.8</td></tr><tr><td colspan="2">*on a dry weight basis</td></tr></table>
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<table><tr><td>Serial no.</td><td>Class of Motifs</td><td>No. of exclusive IFN-&#947; peptide</td><td>No. of exclusive rest of cytokine inducing peptide</td></tr><tr><td>1</td><td>None</td><td>696</td><td>384</td></tr><tr><td>2</td><td>Koolman-Rohm</td><td>1481</td><td>219</td></tr><tr><td>3</td><td>Betts-Russell (Hydorphobic)</td><td>1731</td><td>187</td></tr><tr><td>4</td><td>Betts-Russell (Polar)</td><td>1318</td><td>234</td></tr><tr><td>5</td><td>Betts-Russell (Small)</td><td>1668</td><td>186</td></tr><tr><td>6</td><td>ALL class</td><td>3058</td><td>679</td></tr></table>
2410cb211a6eb61596a5c95d7d052c891e32d88cf7acb900a7c7a6bb0f115ea1.png
simple
<table><tr><td></td><td>22q11DSMean (SD)</td><td>Median</td><td>HCMean (SD)</td><td>Median</td><td>Statistic (<i>p</i>), effect size (<i>r</i>)</td></tr><tr><td>BORB</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td> Field dependence/independence</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Figure-ground segmentation</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Single letters</td><td>0.90 (0.1)</td><td>0.92</td><td>0.84 (0.1)</td><td>0.84</td><td>0.04 (0.23) NS</td></tr><tr><td>Paired drawings</td><td>0.97 (0.2)</td><td>0.97</td><td>0.88 (0.1)</td><td>0.89</td><td>0.40 (0.08) NS</td></tr><tr><td>Triplet letters</td><td>0.96 (0.1)</td><td>0.95</td><td>0.95 (0.2)</td><td>0.88</td><td>0.03 (0.23) NS</td></tr><tr><td> Form perception</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Form perception easy sub-tests (easy foreshortened + easy minimal features)</td><td>47.20 (2.78)</td><td>48.0</td><td>49.13 (1.38)</td><td>50.0</td><td>0.001 (0.43)</td></tr><tr><td>Form perception hard sub-tests (hard foreshortened + hard minimal features)</td><td>38.91 (4.1)</td><td>40.0</td><td>41.76 (1.8)</td><td>43.0</td><td>0.001 (0.43)</td></tr><tr><td> Visual object recognition</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Picture naming</td><td>12.56 (1.87)</td><td>13.0</td><td>13.70 (1.66)</td><td>14.0</td><td>0.001 (0.37)</td></tr><tr><td> Implicit memory</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Object decision (easy)</td><td>28.04 (3.94)</td><td></td><td>29.83 (1.49)</td><td></td><td></td></tr><tr><td>Object decision (hard)</td><td>24.7 0(3.48)</td><td></td><td>26.53 (3.03)</td><td></td><td></td></tr><tr><td> Implicit memory sub-total</td><td>53.04 (5.88)</td><td>54.0</td><td>56.37 (3.36)</td><td>57.0</td><td>0.003 (0.33)</td></tr><tr><td> Semantic memory</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Associative matching</td><td>27.29 (3.07)</td><td>28.0</td><td>29.27 (1.08)</td><td>30.0</td><td>0.001 (0.44)</td></tr><tr><td> Embedded figures test</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Total score</td><td>21.10 (4.0)</td><td>22.0</td><td>22.22 (1.85)</td><td>23.0</td><td>0.5 (0.09) NS</td></tr><tr><td>Reaction time (s)</td><td>33.89 (17.1)</td><td>30.3</td><td>26.76 (12.06)</td><td>24.3</td><td>0.07 (0.22) NS</td></tr></table>
738e02c7dd89aa4b862db440f6a8021ba6633fdd23519f0302cd1f845f03d91d.png
simple
<table><tr><td>Receptor</td><td>t<sub>1/2</sub></td></tr><tr><td>LRP</td><td>0.5 min</td></tr><tr><td>LDLR</td><td>4.8 min</td></tr><tr><td>ApoER2</td><td>8.1 min</td></tr><tr><td>VLDLR</td><td>8.2 min</td></tr></table>
ad2ab8056ebc1cb4b860f90da288152399ee02bfe40f2abeecf2aeba5d24231f.png
complex
<table><tr><td rowspan="3">SNPs</td><td rowspan="3">Chr</td><td rowspan="3">Gene</td><td rowspan="3">A1</td><td rowspan="3">MAF</td><td rowspan="2" colspan="2">Identification LifeLines I</td><td colspan="4">Replication</td><td rowspan="2" colspan="2">Meta-analysis Replication</td></tr><tr><td colspan="2">LifeLines II</td><td colspan="2">Vlagtwedde-Vlaardingen</td></tr><tr><td>OR</td><td>P</td><td>OR</td><td>P</td><td>OR</td><td>P</td><td>OR</td><td>P</td></tr><tr><td>rs11813494</td><td>10</td><td>638 kb 3&#8242; of SFTA1P</td><td>G</td><td>0.24</td><td>1.279</td><td>1.12E-06</td><td>1.110</td><td>0.114</td><td>0.776</td><td>0.096</td><td>1.049</td><td>0.427</td></tr><tr><td>rs840952</td><td>2</td><td>60 kb 5&#8242; of SPRED2</td><td>G</td><td>0.10</td><td>1.212</td><td>1.09E-05</td><td>1.168</td><td>0.006</td><td>0.814</td><td>0.169</td><td>1.035</td><td>0.401</td></tr><tr><td>rs7633390</td><td>3</td><td>27 kb 5&#8242; of ZNF717</td><td>T</td><td>0.18</td><td>1.237</td><td>2.24E-05</td><td>1.037</td><td>0.581</td><td>0.865</td><td>0.305</td><td>1.005</td><td>0.938</td></tr><tr><td>rs4977230</td><td>9</td><td>SLC24A2</td><td>T</td><td>0.71</td><td>0.817</td><td>3.35E-05</td><td>1.020</td><td>0.744</td><td>0.986</td><td>0.910</td><td>1.013</td><td>0.806</td></tr><tr><td>rs4780334</td><td>16</td><td>CIITA</td><td>G</td><td>0.69</td><td>1.209</td><td>3.78E-05</td><td>0.985</td><td>0.802</td><td>0.875</td><td>0.295</td><td>0.964</td><td>0.500</td></tr><tr><td>rs844033</td><td>15</td><td>126 kb 5&#8242; of NDN</td><td>C</td><td>0.91</td><td>0.702</td><td>3.84E-05</td><td>1.163</td><td>0.115</td><td>1.213</td><td>0.342</td><td>1.172</td><td>0.068</td></tr><tr><td>rs422564</td><td>5</td><td>3.9 kb 3&#8242; of TBCA</td><td>T</td><td>0.21</td><td>1.201</td><td>3.97E-05</td><td>1.035</td><td>0.549</td><td>1.196</td><td>0.123</td><td>1.065</td><td>0.222</td></tr><tr><td>rs12153520</td><td>5</td><td>77 kb 3&#8242; of HINT1</td><td>A</td><td>0.16</td><td>1.259</td><td>4.48E-05</td><td>1.012</td><td>0.875</td><td>1.020</td><td>0.904</td><td>1.013</td><td>0.844</td></tr><tr><td>rs893966</td><td>1</td><td>EPHB2</td><td>T</td><td>0.50</td><td>1.248</td><td>4.72E-05</td><td>0.992</td><td>0.909</td><td>0.909</td><td>0.532</td><td>0.975</td><td>0.707</td></tr><tr><td>rs6775462</td><td>3</td><td>ROBO2</td><td>C</td><td>0.50</td><td>0.739</td><td>4.81E-05</td><td>0.952</td><td>0.588</td><td>1.124</td><td>0.497</td><td>0.987</td><td>0.869</td></tr><tr><td>rs4766584</td><td>12</td><td>ACACB</td><td>G</td><td>0.45</td><td>0.821</td><td>5.15E-05</td><td>0.929</td><td>0.234</td><td>0.994</td><td>0.964</td><td>0.941</td><td>0.274</td></tr><tr><td>rs16918212</td><td>12</td><td>A2MP1</td><td>A</td><td>0.20</td><td>0.717</td><td>5.41E-05</td><td>0.882</td><td>0.196</td><td>0.613</td><td>0.021</td><td>0.828</td><td>0.033</td></tr><tr><td>rs2623166</td><td>8</td><td>GEM</td><td>T</td><td>0.13</td><td>1.293</td><td>7.68E-05</td><td>0.994</td><td>0.948</td><td>0.635</td><td>0.029</td><td>0.928</td><td>0.360</td></tr><tr><td>rs17729233</td><td>18</td><td>DSG4</td><td>G</td><td>0.44</td><td>1.257</td><td>7.89E-05</td><td>1.034</td><td>0.668</td><td>0.997</td><td>0.982</td><td>1.026</td><td>0.714</td></tr><tr><td>rs2850106</td><td>21</td><td>HLCS</td><td>G</td><td>0.12</td><td>0.839</td><td>8.29E-05</td><td>1.050</td><td>0.384</td><td>0.998</td><td>0.989</td><td>1.040</td><td>0.434</td></tr><tr><td>rs10758982</td><td>9</td><td>PTPRD</td><td>G</td><td>0.34</td><td>1.211</td><td>8.36E-05</td><td>0.967</td><td>0.602</td><td>0.827</td><td>0.163</td><td>0.939</td><td>0.284</td></tr><tr><td>rs2845804</td><td>21</td><td>HLCS</td><td>C</td><td>0.18</td><td>0.841</td><td>9.93E-05</td><td>0.976</td><td>0.663</td><td>1.090</td><td>0.461</td><td>0.996</td><td>0.941</td></tr></table>
9667c789eae190d1cd11bb2b0198fe16385004f98185a2e549f6be44e086f210.png
complex
<table><tr><td rowspan="2">Index/subtests/development scales</td><td colspan="5">WPPSI-III </td></tr><tr><td><i>N </i></td><td>IQ/DQ/scores</td><td>Subtest mean</td><td>Std. deviation</td><td>Range</td></tr><tr><td>WPPSI verbal IQ (VIQ)</td><td>113</td><td>84,8</td><td> </td><td>16,1</td><td>53&#8211;133</td></tr><tr><td>Information</td><td>112</td><td> </td><td>7,4</td><td>3,3</td><td>1&#8211;16</td></tr><tr><td>Vocabulary</td><td>110</td><td> </td><td>7,4</td><td>2,9</td><td>2&#8211;16</td></tr><tr><td>Word Reasoning</td><td>111</td><td> </td><td>7,2</td><td>3,1</td><td>1&#8211;15</td></tr><tr><td>Comprehension</td><td>63</td><td> </td><td>9,0</td><td>2,9</td><td>3&#8211;15</td></tr><tr><td>Similarities</td><td>67</td><td> </td><td>7,9</td><td>2,6</td><td>3&#8211;15</td></tr><tr><td>WPPSI performance IQ (PIQ)</td><td>113</td><td>93,6</td><td> </td><td>16,7</td><td>53&#8211;135</td></tr><tr><td>Block Design</td><td>112</td><td> </td><td>10,3</td><td>3,6</td><td>1&#8211;18</td></tr><tr><td>Matrix Reasoning</td><td>111</td><td> </td><td>8,8</td><td>3,5</td><td>1&#8211;16</td></tr><tr><td>Picture Concepts</td><td>111</td><td> </td><td>8,2</td><td>3,4</td><td>1&#8211;17</td></tr><tr><td>Picture Completion</td><td>67</td><td> </td><td>9,6</td><td>3,5</td><td>2&#8211;19</td></tr><tr><td>WPPSI Processing speed (PSQ)</td><td>85</td><td>76,7</td><td> </td><td>12,2</td><td>49&#8211;107</td></tr><tr><td>Coding</td><td>110</td><td> </td><td>5,1</td><td>2,9</td><td>1&#8211;12</td></tr><tr><td>Symbol Search</td><td>95</td><td> </td><td>5,9</td><td>2,6</td><td>2&#8211;14</td></tr><tr><td>WPPSI General Language (GLC)</td><td>99</td><td>89,9</td><td> </td><td>17,1</td><td>45&#8211;128</td></tr><tr><td>Receptive Vocabulary</td><td>96</td><td> </td><td>8,2</td><td>3,1</td><td>1&#8211;15</td></tr><tr><td>Picture Naming</td><td>95</td><td> </td><td>8,5</td><td>3,2</td><td>2&#8211;16</td></tr><tr><td>WPPSI full scale IQ (FSIQ)</td><td>113</td><td>84,5</td><td> </td><td>14,7</td><td>51&#8211;121</td></tr><tr><td>Griffiths' verbal functioning</td><td>77</td><td>33,5</td><td> </td><td>15,9</td><td>8&#8211;72</td></tr><tr><td>Griffiths' performance functioning</td><td>77</td><td>46,7</td><td> </td><td>16,3</td><td>15&#8211;79</td></tr><tr><td>Griffiths' global functioning</td><td>77</td><td>41,6</td><td> </td><td>14,5</td><td>13&#8211;73</td></tr><tr><td>VABS Communication</td><td>187</td><td>71,9</td><td> </td><td>18,9</td><td>34&#8211;120</td></tr><tr><td>VABS DLS</td><td>187</td><td>73,8</td><td> </td><td>16,4</td><td>38&#8211;117</td></tr><tr><td>VABS Socialization</td><td>187</td><td>70,6</td><td> </td><td>14,7</td><td>46&#8211;112</td></tr><tr><td>VABS Motor</td><td>187</td><td>76,4</td><td> </td><td>14,5</td><td>43&#8211;117</td></tr><tr><td>VABS total</td><td>187</td><td>70,5</td><td> </td><td>15,0</td><td>42&#8211;114</td></tr></table>
58d177b14fb42c4864b15c21f9fa5b70b17d6e1c131cfabcd2298b059b0f0912.png
complex
<table><tr><td colspan="2">Variable</td></tr><tr><td colspan="2">Stroke severity on admission, <i>n</i> (%)</td></tr><tr><td>NIHSS 0&#8211;5</td><td>36 (27.5)</td></tr><tr><td>NIHSS 6&#8211;10</td><td>46 (35.1)</td></tr><tr><td>NIHSS 11&#8211;16</td><td>29 (22.1)</td></tr><tr><td>NIHSS &gt;16</td><td>17 (13.0)</td></tr><tr><td>Undetermined</td><td>3 (2.3)</td></tr><tr><td colspan="2">Stroke etiology (TOAST), <i>n</i> (%)</td></tr><tr><td>Large artery atherosclerosis</td><td>49 (37.4)</td></tr><tr><td>Small vessel occlusion</td><td>13 (9.9)</td></tr><tr><td>Cardioembolic</td><td>27 (20.6)</td></tr><tr><td>Other/undetermined</td><td>42 (32.1)</td></tr><tr><td colspan="2">Imaging data</td></tr><tr><td colspan="2">ASPECTS, median (IQR)</td></tr><tr><td> On admission</td><td>10 (9&#8211;10)</td></tr><tr><td> 24 h after thrombolysis</td><td>9 (5&#8211;10)</td></tr><tr><td colspan="2">Affected vessel territory, <i>n</i> (%)</td></tr><tr><td> MCA</td><td>82 (62.6)</td></tr><tr><td> ICA</td><td>11 (8.4)</td></tr><tr><td> MCA + ICA</td><td>10 (7.6)</td></tr><tr><td> VB</td><td>28 (21.4)</td></tr><tr><td colspan="2">Level of occlusion, <i>n</i> (%)</td></tr><tr><td> No stenosis/occlusion</td><td>34 (26.0)</td></tr><tr><td> Stenosis</td><td>27 (20.6)</td></tr><tr><td> Occlusion</td><td>70 (53.4)</td></tr><tr><td colspan="2">Outcomes, <i>n</i> (%)</td></tr><tr><td colspan="2">Functional outcome at 7 days</td></tr><tr><td> Favorable outcome</td><td>49 (37.4)</td></tr><tr><td> No change</td><td>42 (32.1)</td></tr><tr><td> Unfavorable outcome</td><td>20 (15.3)</td></tr><tr><td colspan="2">Functional outcome at 90 days</td></tr><tr><td> mRS 0&#8211;2</td><td>57 (43.5)</td></tr><tr><td> mRS 3&#8211;6</td><td>51 (38.9)</td></tr><tr><td> Undetermined</td><td>23 (17.6)</td></tr><tr><td colspan="2">Intracranial hemorrhage (ECASS II)</td></tr><tr><td> aSICH</td><td>7 (5.3)</td></tr><tr><td> SICH</td><td>6 (4.6)</td></tr></table>
609ec7c388809a852e7fe1b4b1f8c7d7371a1b08def338153bb7e2f2a45e1c8c.png
complex
<table><tr><td rowspan="2" colspan="2">Group</td><td colspan="2">Body weight in grams (SEM)</td></tr><tr><td>Baseline</td><td>Post-test</td></tr><tr><td rowspan="2">Male</td><td>Ctrl</td><td>297.2 (3.4)</td><td>350.0* (7.1)</td></tr><tr><td>SPS</td><td>297.5 (4.9)</td><td>341.9* (7.9)</td></tr><tr><td rowspan="2">Female</td><td>Ctrl</td><td>191.5 (3.0)</td><td>213.9* (5.4)</td></tr><tr><td>SPS</td><td>194.5 (3.0)</td><td>214.8* (3.2)</td></tr></table>
eddc3f31b7130b14bf0865020f8ad2b134dabd33064bcf19664560380c93499a.png
complex
<table><tr><td>Variables</td><td>Instruments</td><td colspan="3">Time of Measurement</td></tr><tr><td></td><td></td><td>Baseline/1 week after discharge ICU</td><td>6 months</td><td>12 months</td></tr><tr><td>Pain (intensity, frequency)</td><td>NRS</td><td>Q</td><td>Q</td><td>Q</td></tr><tr><td>Anxiety (intensity, frequency)</td><td>NRS, HADS-D</td><td>Q</td><td>Q</td><td>Q</td></tr><tr><td>Agitation (intensity, frequency)</td><td>CAM</td><td>Q</td><td>Q</td><td>Q</td></tr><tr><td>Mortality</td><td>Survival: Yes/No</td><td>Q</td><td>Q</td><td>Q</td></tr><tr><td>Morbidity</td><td>International classification of diseases, version 10</td><td>MR/Q</td><td>MR/Q</td><td>MR/Q</td></tr><tr><td>Quality of life (HR-QOL)<sup>1</sup></td><td>SF-36</td><td>Q</td><td>Q</td><td>Q</td></tr></table>
69b830dd5bc50749b6db9392fba4e0cac55b92359abcfd1a62c23d51f7eb380b.png
simple
<table><tr><td></td><td>Baseline</td><td>Intervention</td><td>Difference</td><td>p-value <sup>a</sup></td></tr><tr><td>Simple reactiontime test</td><td></td><td></td><td></td><td></td></tr><tr><td>Mean Tput <sup>b </sup>score (SE)</td><td>209 (6)</td><td>220 (6)</td><td>11 (4)</td><td>0.01</td></tr><tr><td>Mean reaction time in msec (SE)</td><td>293 (9)</td><td>279 (9)</td><td>-15 (7)</td><td>0.03</td></tr><tr><td>Complex reactiontime test</td><td></td><td></td><td></td><td></td></tr><tr><td>Mean Tput <sup>b </sup>score (SE)</td><td>85 (3)</td><td>92 (4)</td><td>7 (2)</td><td>&lt; 0.001</td></tr><tr><td>Mean reaction time in msec (SE)</td><td>629 (18)</td><td>606 (21)</td><td>-23 (8)</td><td>0.002</td></tr><tr><td>Mean % correct (SE)</td><td>97.5 (0.4)</td><td>98.2 (0.3)</td><td>0.7 (0.3)</td><td>0.01</td></tr><tr><td>Mean lapses <sup>c </sup>(SE)</td><td>5.5 (0.9)</td><td>4.3 (1.0)</td><td>-1.2 (0.6)</td><td>0.05</td></tr><tr><td>Mean impulses <sup>d </sup>(SE)</td><td>6.1 (0.8)</td><td>4.5 (0.9)</td><td>-1.6 (0.4)</td><td>&lt; 0.001</td></tr></table>
70987332b1b033de12f5103f0885a77d140a3a45b351f9557948ad18d745f29f.png
simple
<table><tr><td>Platform</td><td>Cost (US$)</td></tr><tr><td>Vinoculer</td><td>5 K</td></tr><tr><td>UAV</td><td>16&#8211;80 K</td></tr></table>
7231d32e0eaaca112f022ee5c9f922d25ae3b63f585b992e1d800e9da0df9c2d.png
simple
<table><tr><td></td><td>Unsuccessful Breastfeeding</td><td>Successful Breastfeeding</td><td><i>P</i>-value, Wilcox rank sum test</td></tr><tr><td>VAS 6 Hours</td><td><i>n</i> = 10</td><td><i>n</i> = 73</td><td></td></tr><tr><td> Median (Q1/Q3)</td><td>1.5 (0/4)</td><td>3 (0/4)</td><td>0.56</td></tr><tr><td> Mean (Upper/Lower 95%)</td><td>2.0 (0.7-3.4)</td><td>2.73 (2.1-3.3)</td><td></td></tr><tr><td>VAS 12 Hours</td><td><i>n</i> = 9</td><td><i>n</i> = 75</td><td></td></tr><tr><td> Median (Q1/Q3)</td><td>1 (0/1)</td><td>2 (0/5)</td><td>0.39</td></tr><tr><td> Mean (Upper/Lower 95%)</td><td>1.6 (0-3.3)</td><td>2.6 (1.9-3.2)</td><td></td></tr><tr><td>VAS 24 h</td><td><i>n</i> = 10</td><td><i>n</i> = 80</td><td></td></tr><tr><td> Mean (Upper/Lower 95%)</td><td>4.5 (2/6)</td><td>3 (1/5)</td><td>0.31</td></tr><tr><td> Median (Q1/Q3)</td><td>4.1 (2.2-6.1)</td><td>3.2 (2.6-3.8)</td><td></td></tr></table>
f13a6ec9c98cfcaeb6e593b8d3dd07820256e2ca9005a60512aa7e005c3b54c1.png
simple
<table><tr><td>Author</td><td>Sample size</td><td>Prevalence (%)</td><td>Sensitivity (%)</td><td>Specificity (%)</td><td>PPV (%)</td><td>NPV (%)</td></tr><tr><td>Gaspari et al. [39]</td><td>104</td><td>51</td><td>87</td><td>82</td><td>84</td><td>86</td></tr><tr><td>Watkins et al. [40]</td><td>57</td><td>68</td><td>80</td><td>83</td><td>91</td><td>65</td></tr><tr><td>Moak et al. [41]</td><td>107</td><td>36</td><td>76</td><td>78</td><td>66</td><td>86</td></tr><tr><td>Herbst et al. [42]</td><td>670</td><td>47</td><td>73</td><td>73</td><td>71</td><td>75</td></tr></table>