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1878b9c55e29f73e0ea05c8b5b21f2577c0dc2139a458583c7edcf652e0cf1e9.png | simple | <table><tr><td><i>Regression parameter</i></td><td><i>Slope (a)</i></td><td><i>Intercept (b)</i></td><td><i>Data point count</i></td><td><i>R<sup>2</sup></i></td></tr><tr><td>value</td><td>1.09</td><td>0.03</td><td>679</td><td>0.98</td></tr></table> |
45cee9d364298a017be7904f867e751a0b16811e31cee8d1a9e5e2f2a3765e83.png | complex | <table><tr><td rowspan="2"></td><td colspan="2">CA125 (U/ml)</td><td colspan="2">HE4 (pmol/l)</td><td colspan="2">ROMA (%)</td><td colspan="2">ROMA P (%)</td><td rowspan="2">p (ROMA vs. ROMA P)</td></tr><tr><td>Median</td><td>Range</td><td>Median</td><td>Range</td><td>Median</td><td>Range</td><td>Median</td><td>Range</td></tr><tr><td>Ovarian cancer (all)</td><td>397.5</td><td>9–7459.1</td><td>340.7</td><td>12–9264</td><td>90.3</td><td>0.5–100</td><td>91.46</td><td>1.33–99.9</td><td>0.8641</td></tr><tr><td> Serous</td><td>421.1</td><td>9–7459.1</td><td>390.7</td><td>15–9264</td><td>91.9</td><td>0.5–100</td><td>92.5</td><td>1.3–99.9</td><td>0.7963</td></tr><tr><td> Mucinous</td><td>58.8</td><td>11.3–600</td><td>69.2</td><td>15–538</td><td>30.1</td><td>6.2–95.8</td><td>27.2</td><td>1.9–96.1</td><td>0.9699</td></tr><tr><td> Clear cell</td><td>389.9</td><td>95.8–1725.5</td><td>184.8</td><td>49.5–849.9</td><td>81.5</td><td>8.1–98.2</td><td>73.7</td><td>15.6–98.3</td><td>0.9581</td></tr><tr><td> Endometrioid</td><td>00</td><td>41.5–2996.8</td><td>340.7</td><td>46.1–1235</td><td>94.6</td><td>21–99.3</td><td>93.2</td><td>2.5–99.4</td><td>0.9591</td></tr><tr><td> FIGO stages I and II</td><td>130.3</td><td>9–2347</td><td>79</td><td>15–1235</td><td>35.3</td><td>0.5–99.3</td><td>33.6</td><td>1.3–99.3</td><td>0.8610</td></tr><tr><td> FIGO stages III and IV</td><td>591</td><td>18–7459.1</td><td>593.75</td><td>20.7–9264</td><td>96.8</td><td>9–100</td><td>97.1</td><td>10.1–99.9</td><td>0.6691</td></tr><tr><td> Grade 1</td><td>68.2</td><td>9–459.7</td><td>70.8</td><td>15–414.3</td><td>20.5</td><td>0.5–93.9</td><td>23.1</td><td>1.3–93.8</td><td>0.9087</td></tr><tr><td> Grade 2</td><td>420.1</td><td>14–7459.1</td><td>289.3</td><td>20.7–9264</td><td>88.5</td><td>8.4–100</td><td>88.9</td><td>10.1–99.9</td><td>0.0114</td></tr><tr><td> Grade 3</td><td>535.1</td><td>11.2–5109.8</td><td>569.8</td><td>20.4–8160</td><td>96.7</td><td>1–100</td><td>96.4</td><td>2.98–99.9</td><td>0.8963</td></tr><tr><td>Benign diseases (all)</td><td>22.5</td><td>3.2–502.7</td><td>46.7</td><td>17.8–206.5</td><td>6.7</td><td>0.7–87</td><td>8.29</td><td>1.15–85.2</td><td>0.0001</td></tr><tr><td> Endometriosis</td><td>45.5</td><td>6.7–377</td><td>45.2</td><td>17.8–86.7</td><td>6.6</td><td>0.7–35.34</td><td>9.1</td><td>1.2–26.16</td><td>0.2295</td></tr><tr><td> Teratoma tumors</td><td>15.5</td><td>6.3–51.9</td><td>46.6</td><td>26.3–724</td><td>6.48</td><td>1.65–17.9</td><td>6.76</td><td>1.87–17.6</td><td>0.2835</td></tr><tr><td> Follicular cysts</td><td>14.5</td><td>3.2–88</td><td>55.3</td><td>24.2–206.5</td><td>8.76</td><td>1.6–65.7</td><td>9.9</td><td>1.6–67.8</td><td>0.4886</td></tr><tr><td> Paraovarian cysts</td><td>13.7</td><td>4.1–52.7</td><td>48.6</td><td>36.4–186.8</td><td>7.5</td><td>3.7–87</td><td>7.9</td><td>3.8–85.2</td><td>0.7075</td></tr><tr><td> Hemorrhagic cysts</td><td>15.4</td><td>5.5–274.8</td><td>44.3</td><td>24.8–95.7</td><td>5.7</td><td>1.7–31.6</td><td>6.5</td><td>3.2–30.9</td><td>0.6522</td></tr><tr><td colspan="10">AGE interval</td></tr><tr><td> W1 ovarian cancer group</td><td>–</td><td>–</td><td>–</td><td>–</td><td>–</td><td>–</td><td>–</td><td>–</td><td>–</td></tr><tr><td> W2 ovarian cancer group</td><td>55.2</td><td>27–135.1</td><td>45.4</td><td>44.1–103.9</td><td>6.2</td><td>6–35</td><td>7.5</td><td>7.1–37.7</td><td>0.3827</td></tr><tr><td> W3 ovarian cancer group</td><td>403.6</td><td>98.1–1252</td><td>95.4</td><td>15–464.8</td><td>31.5</td><td>0.5–95.5</td><td>43.6</td><td>1.3–95.6</td><td>0.3619</td></tr><tr><td> W4 ovarian cancer group</td><td>265.4</td><td>14–4638.8</td><td>92.9</td><td>15–1500</td><td>34.7</td><td>0.5–99.7</td><td>44.7</td><td>1.3–99.4</td><td>0.7743</td></tr><tr><td> W5 ovarian cancer group</td><td>500</td><td>9–5887</td><td>439.3</td><td>12–1655</td><td>96.4</td><td>4.5–99.7</td><td>96.3</td><td>1.9–99.8</td><td>0.7883</td></tr><tr><td> W6 ovarian cancer group</td><td>233.3</td><td>9.8–7459.1</td><td>334.5</td><td>22–9264</td><td>90.9</td><td>6–100</td><td>91.6</td><td>5.2–99.9</td><td>0.9786</td></tr><tr><td> W7 ovarian cancer group</td><td>839</td><td>21–5659</td><td>658.4</td><td>37–8160</td><td>97</td><td>25–100</td><td>97.2</td><td>23.8–99.9</td><td>0.7710</td></tr><tr><td> W8 ovarian cancer group</td><td>777.5</td><td>66.9–3724</td><td>871.2</td><td>85.8–4940</td><td>97.7</td><td>55.1–100</td><td>97.9</td><td>55.1–99.9</td><td>1.0000</td></tr><tr><td> W1 benign group</td><td>16</td><td>4.1–274.8</td><td>41.5</td><td>24.2–84.7</td><td>6.2</td><td>1.56–22.1</td><td>6.4</td><td>1.56–22.1</td><td>0.9420</td></tr><tr><td> W2 benign group</td><td>28.1</td><td>7.7–377</td><td>45.5</td><td>26.3–80.4</td><td>5.4</td><td>1.65–20.3</td><td>6.2</td><td>1.87–22.7</td><td>0.0913</td></tr><tr><td> W3 benign group</td><td>32.3</td><td>7.1–191.5</td><td>47.3</td><td>31.7–86.7</td><td>7</td><td>2.6–24.1</td><td>9.2</td><td>3.2–26.2</td><td>0.9529</td></tr><tr><td> W4 benign group</td><td>21.6</td><td>5.5–168.8</td><td>44.5</td><td>17.8–74.2</td><td>6</td><td>0.7–17.6</td><td>8.9</td><td>1.15–21.3</td><td>0.0079</td></tr><tr><td> W5 benign group</td><td>12.4</td><td>3.2–82.1</td><td>48.5</td><td>27.5–85.1</td><td>6.9</td><td>1.8–35.3</td><td>8.4</td><td>4.4–23.4</td><td>0.6641</td></tr><tr><td> W6 benign group</td><td>15.9</td><td>6.7–79.8</td><td>63.8</td><td>47.1–206.5</td><td>14.3</td><td>6.7–65.7</td><td>14.1</td><td>6.6–67.8</td><td>0.6232</td></tr><tr><td> W7 benign group</td><td>9.55</td><td>6.3–52.7</td><td>69.5</td><td>52–186</td><td>9.7</td><td>7.3–87</td><td>9.7</td><td>7.6–85.2</td><td>1.0000</td></tr></table> |
d1b16036854970122f03e5c907eefb06510bd0f7a5f9babb7776f9a9d3dc1d4e.png | complex | <table><tr><td rowspan="2">Genogroup rate used</td><td rowspan="2">Segregation</td><td rowspan="2">Time (yr) since divergence<sup><i>a</i></sup></td><td colspan="2">95% CI<sup><i>b</i></sup></td></tr><tr><td>Lower</td><td>Upper</td></tr><tr><td>5B and 5A</td><td>5A and 5B</td><td>7.14</td><td>1.71</td><td>28.36</td></tr><tr><td></td><td>5B and Bandim 6</td><td>3.47</td><td>0.86</td><td>13.70</td></tr><tr><td></td><td>5B and Bandim 13/14</td><td>2.00</td><td>0.53</td><td>7.91</td></tr><tr><td>5B only</td><td>5A and 5B</td><td>2.29</td><td>1.68</td><td>2.95</td></tr><tr><td></td><td>5B and Bandim 6</td><td>1.16</td><td>0.79</td><td>1.61</td></tr><tr><td></td><td>5B and Bandim 13/14</td><td>0.81</td><td>0.56</td><td>1.12</td></tr><tr><td>Firth et al. (26)</td><td>5A and 5B</td><td>30.37</td><td>20.85</td><td>41.05</td></tr><tr><td></td><td>5B and Bandim 6</td><td>14.21</td><td>8.26</td><td>21.24</td></tr><tr><td></td><td>5B and Bandim 13/14</td><td>8.03</td><td>3.87</td><td>12.93</td></tr></table> |
d7a18b2391ef5f620d7f7cb41c84d03475a0249b664e673bfadf43f2258bd82a.png | complex | <table><tr><td rowspan="2">Month</td><td colspan="3">2008</td><td colspan="3">2009</td><td colspan="3">2010</td><td colspan="3">2011</td><td colspan="3">2012</td></tr><tr><td>Total</td><td colspan="2">Positive</td><td>Total</td><td colspan="2">Positive</td><td>Total</td><td colspan="2">Positive</td><td>Total</td><td colspan="2">Positive</td><td>Total</td><td colspan="2">Positive</td></tr><tr><td> </td><td> </td><td>n</td><td>%</td><td> </td><td>n</td><td>%</td><td> </td><td>n</td><td>%</td><td> </td><td>n</td><td>%</td><td> </td><td>n</td><td>%</td></tr><tr><td>January</td><td>10</td><td>6</td><td>60</td><td>8</td><td>1</td><td>13</td><td>16</td><td>5</td><td>31</td><td>14</td><td>3</td><td>21</td><td>6</td><td>1</td><td>17</td></tr><tr><td>February</td><td>16</td><td>3</td><td>19</td><td>13</td><td>4</td><td>31</td><td>13</td><td>3</td><td>23</td><td>15</td><td>7</td><td>47</td><td>12</td><td>5</td><td>42</td></tr><tr><td>March</td><td>18</td><td>5</td><td>28</td><td>16</td><td>5</td><td>31</td><td>16</td><td>2</td><td>13</td><td>26</td><td>15</td><td>58</td><td>18</td><td>9</td><td>50</td></tr><tr><td>April</td><td>3</td><td>1</td><td>33</td><td>21</td><td>8</td><td>38</td><td>21</td><td>7</td><td>33</td><td>26</td><td>15</td><td>58</td><td>35</td><td>24</td><td>69</td></tr><tr><td>May</td><td>15</td><td>2</td><td>13</td><td>22</td><td>9</td><td>41</td><td>23</td><td>6</td><td>26</td><td>24</td><td>12</td><td>50</td><td>23</td><td>11</td><td>48</td></tr><tr><td>June</td><td>15</td><td>3</td><td>20</td><td>24</td><td>7</td><td>29</td><td>26</td><td>3</td><td>12</td><td>15</td><td>10</td><td>67</td><td>22</td><td>6</td><td>27</td></tr><tr><td>July</td><td>5</td><td>1</td><td>20</td><td>24</td><td>7</td><td>29</td><td>29</td><td>8</td><td>28</td><td>18</td><td>4</td><td>22</td><td>-</td><td>-</td><td>-</td></tr><tr><td>August</td><td>8</td><td>2</td><td>25</td><td>17</td><td>3</td><td>18</td><td>18</td><td>6</td><td>33</td><td>16</td><td>4</td><td>25</td><td>-</td><td>-</td><td>-</td></tr><tr><td>September</td><td>5</td><td>1</td><td>20</td><td>10</td><td>4</td><td>40</td><td>22</td><td>9</td><td>41</td><td>15</td><td>7</td><td>47</td><td>-</td><td>-</td><td>-</td></tr><tr><td>October</td><td>10</td><td>5</td><td>50</td><td>27</td><td>5</td><td>19</td><td>25</td><td>11</td><td>44</td><td>26</td><td>15</td><td>58</td><td>-</td><td>-</td><td>-</td></tr><tr><td>November</td><td>25</td><td>11</td><td>44</td><td>21</td><td>6</td><td>29</td><td>27</td><td>5</td><td>19</td><td>17</td><td>7</td><td>41</td><td>-</td><td>-</td><td>-</td></tr><tr><td>December</td><td>13</td><td>6</td><td>46</td><td>39</td><td>13</td><td>33</td><td>24</td><td>6</td><td>25</td><td>30</td><td>13</td><td>43</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Total</td><td>143</td><td>46</td><td>32</td><td>242</td><td>72</td><td>30</td><td>260</td><td>71</td><td>27</td><td>242</td><td>112</td><td>46</td><td>116</td><td>56</td><td>48</td></tr></table> |
cbb629d62ce516ca336071caa9b2d66994e2f902b85b629d5eaf666707b6a10f.png | complex | <table><tr><td></td><td></td><td colspan="2">Baseline</td><td colspan="2">Postexposure</td><td></td></tr><tr><td>Outcome</td><td><i>n</i>a</td><td>Mean ± SD</td><td>Range</td><td>Mean ± SD</td><td>Range</td><td><i>p</i>-Value</td></tr><tr><td>White blood cells (10<sup>3</sup>/mm<sup>3</sup>)</td><td>62</td><td>7.31 ± 1.6</td><td>3.6–10.4</td><td>7.3 ± 1.7</td><td>4.0–13.0</td><td>0.91</td></tr><tr><td>Granulocytes (%)</td><td>62</td><td>58.9 ± 7.2</td><td>43.5–76.0</td><td>58.2 ± 7.6</td><td>44.6–80.6</td><td>0.23</td></tr><tr><td>Lymphocytes (%)</td><td>62</td><td>30.7 ± 6.7</td><td>15.4–44.1</td><td>32.0 ± 7.3</td><td>15.7–47.0</td><td>0.069</td></tr><tr><td>Monocytes (%)</td><td>62</td><td>10.4 ± 3.5</td><td>4.5–19.4</td><td>9.8 ± 3.5</td><td>3.7–17.5</td><td>0.22</td></tr><tr><td>LTL (T/S ratio)</td><td>57</td><td>1.23 ± 0.28</td><td>0.68–1.86</td><td>1.43 ± 0.51</td><td>0.72–3.34</td><td>< 0.001</td></tr><tr><td><i>hTERT</i> expression (2<sup>−ΔΔCT</sup>)</td><td>58</td><td>1.68 ± 0.86</td><td>0.72–4.86</td><td>1.31 ± 0.75</td><td>0.52–5.55</td><td>< 0.001</td></tr><tr><td colspan="7"><i>hTERT</i> methylation (% 5mC)</td></tr><tr><td> Position 1</td><td>59</td><td>93.9 ± 1.0</td><td>90.5–96.8</td><td>93.9 ± 1.1</td><td>89.9–96.8</td><td>0.84</td></tr><tr><td> Position 2</td><td>59</td><td>93.8 ± 2.8</td><td>80.4–100.0</td><td>93.6 ± 3.1</td><td>79.2–97.1</td><td>0.67</td></tr><tr><td> Position 3</td><td>59</td><td>90.0 ± 1.9</td><td>86.3–95.5</td><td>90.2 ± 1.5</td><td>85.9–93.2</td><td>0.36</td></tr></table> |
80cff1cf4bc92b53494176570db388f7b88fedd163ed39b3e987c9dfd837b9ab.png | simple | <table><tr><td>Matrix</td><td>Filler</td><td>Code name</td></tr><tr><td>PP-SL262MW</td><td>–</td><td>PP</td></tr><tr><td>PP-SL262MW</td><td>Sol-gel (catalyst: acetic acid)</td><td>PP-Acetic</td></tr><tr><td>PP-SL262MW</td><td>Sol-gel (catalyst: formic acid)</td><td>PP-Formic</td></tr><tr><td>PP-SL262MW</td><td>Sol-gel (catalyst: ammonium hydroxide)</td><td>PP-Base</td></tr><tr><td>PP-SL262MW</td><td>Natural HNT</td><td>PP-HNT</td></tr><tr><td>PP-SL262MW</td><td>Functionalized HNT</td><td>PP-PolyHNT</td></tr><tr><td>PP-SL262MW</td><td>Untreated CNT</td><td>PP-CNT</td></tr><tr><td>PP-SL262MW</td><td>Functionalized CNT</td><td>PP-CNTF</td></tr></table> |
6e0125d2a9c82a53f16e169973a532ff54ebd10dd072a36a0fba8f4cb78cf641.png | complex | <table><tr><td>Factors</td><td>Domain</td><td>Data collected</td><td>Sources of information</td></tr><tr><td rowspan="2">Technical factors</td><td rowspan="2">Reporting system</td><td>Type of new tools introduced by the NTCP and their use</td><td>Interviews</td></tr><tr><td>Availability of tuberculosis and routine information tools</td><td>Observation</td></tr><tr><td rowspan="2"> </td><td rowspan="2">Designer of reporting forms</td><td>Designer of the routine information system</td><td rowspan="2">Interviews</td></tr><tr><td>Changes in the design of routine information after TDTC creation</td></tr><tr><td> </td><td>Complexity of the reporting forms</td><td>Complexity of the tuberculosis and routine information tools</td><td>Interviews</td></tr><tr><td rowspan="2"> </td><td rowspan="2">Procedures</td><td>Rules for tuberculosis and routine data collection,analysis and transmission</td><td>Document review</td></tr><tr><td>Changes in routine HIS procedures following the creation of the TDTC</td><td>Interviews</td></tr><tr><td rowspan="2">Organisational factors</td><td rowspan="2">Information distribution</td><td>Type of reports sent by the hospital before and after the creation of the TDTC</td><td rowspan="2">Interviews</td></tr><tr><td>Services receiving hospital reports</td></tr><tr><td rowspan="2"> </td><td rowspan="2">Interest devoted to reporting</td><td>Motivation of the TDTC staff for reporting</td><td rowspan="2">Interviews</td></tr><tr><td>Motivation of the ward staff members for reporting</td></tr><tr><td rowspan="2"> </td><td rowspan="2">Quarterly HIS supervision</td><td>Staff members supervised in the use of thetuberculosis HIS (frequency)</td><td rowspan="2">Interviews Observation</td></tr><tr><td>Staff members supervised in the use of the routine HIS (frequency)</td></tr><tr><td> </td><td>Training</td><td>Training received on HIS management: trainees and date</td><td>Interviews</td></tr><tr><td rowspan="2">Behavioural factors</td><td rowspan="2">Level of knowledge of content of HIS forms</td><td>Staff members involved in monthly routine reporting</td><td rowspan="2">Interviews</td></tr><tr><td>Knowledge of the content of HIS tools by hospital staff</td></tr><tr><td> </td><td>Skills</td><td>Skills in data collection, processing and analysis</td><td>Interviews</td></tr><tr><td> </td><td>Motivation</td><td>Level of motivation</td><td>Interviews</td></tr><tr><td>Processes</td><td>Data collection</td><td>Data completeness in registers (tuberculosis and routine care data)</td><td>Observation</td></tr><tr><td> </td><td>Data processing</td><td>Availability of tuberculosis and routine reports(period) at the hospital level</td><td>Observation</td></tr><tr><td> </td><td>Data analysis</td><td>Type of analysis conducted on tuberculosis data and on routine data</td><td>Interviews Document review</td></tr><tr><td> </td><td>Data transmission</td><td>Availability of tuberculosis and routine reports (period)at the district and regional levels</td><td>Interviews Observation</td></tr><tr><td> </td><td>Data display andfeedback to nurses</td><td>Type of data displayed (for tuberculosis and routine care data)</td><td>Observation</td></tr><tr><td> </td><td>Data quality checking</td><td>Procedures of data checking and actors involved</td><td>Interviews</td></tr></table> |
dfee5b92d7f9be53a280d45225d19eea9a5517b037ac00e34b9e5a6300964514.png | simple | <table><tr><td>Variables</td><td>Average</td><td>Minimum</td><td>Maximum</td></tr><tr><td>Herd size</td><td>100</td><td>40</td><td>220</td></tr><tr><td>Milk production (kg/herd/year)</td><td>815,429</td><td>340,000</td><td>1,850,000</td></tr><tr><td>Milk production (kg/cow/year)</td><td>8,174</td><td>5,333</td><td>10,434</td></tr><tr><td>Number of present young stock per year</td><td>69</td><td>19</td><td>152</td></tr></table> |
872a260d991d96aa10ac5e1bdb8f193745a90ddfe28bde49775941c2d8742d3c.png | complex | <table><tr><td rowspan="2">Parameter</td><td colspan="3">% found</td></tr><tr><td>Tb<sup>+3</sup></td><td>La<sup>+3</sup></td><td>Ce<sup>+3</sup></td></tr><tr><td>Alkaline degradation FMT added = 20ng/ml</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>100.68 ± 0.87</td><td>100.18 ± 0.59</td><td>100.10 ± 0.58</td></tr><tr><td>Student’s t test</td><td>0.17 (2.78)</td><td>0.53 (2.78)</td><td>0.72 (2.78)</td></tr><tr><td>Variance ratio F test</td><td>1.97 (6.94)</td><td>1.10 (6.94)</td><td>1.14 (6.94)</td></tr><tr><td>Alkaline degradation FMT added= 40ng/ml</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>100.08 ± 0.84</td><td>99.99 ± 0.50</td><td>100.15 ± 0.46</td></tr><tr><td>Student’s t test</td><td>0.84 (2.78)</td><td>0.98 (2.78)</td><td>0.50 (2.78)</td></tr><tr><td>Variance ratio F test</td><td>1.84 (6.94)</td><td>1.54 (6.94)</td><td>1.82 (6.94)</td></tr><tr><td>Oxidative degradation FMT added = 20ng/ml</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>99.87 ± 0.71</td><td>100.88 ± 0.80</td><td>99.90 ± 0.67</td></tr><tr><td>Student’s t test</td><td>0.70 (2.78)</td><td>0.07 (2.78)</td><td>0.76 (2.78)</td></tr><tr><td>Variance ratio F test</td><td>1.31 (6.94)</td><td>1.66 (6.94)</td><td>1.17 (6.94)</td></tr><tr><td>Oxidative degradation FMT added = 40ng/ml</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>99.82 ± 0.48</td><td>99.89 ± 0.52</td><td>100.08 ± 0.73</td></tr><tr><td>Student’s t test</td><td>0.45 (2.78)</td><td>0.66 (2.78)</td><td>0.82 (2.78)</td></tr><tr><td>Variance ratio F test</td><td>1.67 (6.94)</td><td>1.42 (6.94)</td><td>1.39 (6.94)</td></tr><tr><td>Intra-day precision (spiked plasma)</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>100.28 ± 2.09</td><td>99.67 ±1.28</td><td>101.24 ± 1.50</td></tr><tr><td>Inter-day precision (spiked plasma)</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>100.39 ± 1.59</td><td>99.44 ± 1.73</td><td>100.30 ± 0.87</td></tr><tr><td>Intra-day precision (real plasma)</td><td></td><td></td><td></td></tr><tr><td><overline>X</overline>±SD</td><td>97.01 ± 0.75</td><td>103.21 ± 0.65</td><td>102.13 ± 0.74</td></tr></table> |
23d8cf6cf282bbac7cf54b596fd6602373fc89c707c8f383b595559d6ac9157c.png | complex | <table><tr><td rowspan="3"></td><td rowspan="3"><i>J</i> Inertia (Kg/m<sup>2</sup>)</td><td rowspan="3"><i>R</i> Resister (Ohm)</td><td colspan="2"><i>K<sub>t</sub></i> Torque constant (Nm/A)</td><td colspan="2"><i>K<sub>m</sub></i> Restoring constant (Nm/rad)</td></tr><tr><td>Simulation</td><td>Experiment</td><td>Simulation</td><td>Experiment</td></tr><tr><td>X-axis</td><td>3.58e-9</td><td>42</td><td>4.84e-4</td><td>6.25e-4</td><td>4.34e-4</td><td>4.62e-4</td></tr><tr><td>Y-axis</td><td>55.65e-9</td><td>145</td><td>2.14e-2</td><td>2.17e-2</td><td>7.07e-3</td><td>6.28e-3</td></tr></table> |
e4f4cb7a31570868c616987552e617a4cebbbc55ffba9ae84d7c36c45981d417.png | complex | <table><tr><td rowspan="3">Variable</td><td colspan="2">HBV status</td><td rowspan="3"><i>P</i>-value</td></tr><tr><td>Positive</td><td>Negative</td></tr><tr><td>(N = 29)</td><td>(N = 171)</td></tr><tr><td><i>Age group</i></td><td></td><td></td><td>0.211</td></tr><tr><td> <20</td><td>1 (3.4)</td><td>10 (5.8)</td><td></td></tr><tr><td> 20-29</td><td>17 (58.6)</td><td>98 (57.3)</td><td></td></tr><tr><td> 30-39</td><td>11 (37.9)</td><td>45 (26.3)</td><td></td></tr><tr><td> 40-49</td><td>0 (0.0)</td><td>18 (10.5)</td><td></td></tr><tr><td><i>Marital status</i></td><td></td><td></td><td>0.518</td></tr><tr><td> Single</td><td>23 (79.3)</td><td>119 (69.6)</td><td></td></tr><tr><td> Married</td><td>6 (20.7)</td><td>50 (29.2)</td><td></td></tr><tr><td> Divorced</td><td>0 (0.0)</td><td>2 (1.2)</td><td></td></tr><tr><td><i>Educational level</i></td><td></td><td></td><td>0.977</td></tr><tr><td> None</td><td>1 (3.4)</td><td>6 (3.5)</td><td></td></tr><tr><td> Basic</td><td>10 (34.5)</td><td>66 (38.6)</td><td></td></tr><tr><td> Secondary</td><td>16 (55.2)</td><td>89 (52.0)</td><td></td></tr><tr><td> Tertiary</td><td>2 (6.9)</td><td>10 (5.8)</td><td></td></tr><tr><td><i>Working Experience</i> (<i>years</i>)</td><td></td><td></td><td>0.423</td></tr><tr><td> <1</td><td>2 (6.9)</td><td>5 (2.9)</td><td></td></tr><tr><td> 1-5</td><td>15 (51.7)</td><td>83 (48.5)</td><td></td></tr><tr><td> 6-10</td><td>9 (31.0)</td><td>45 (26.3)</td><td></td></tr><tr><td> 11-15</td><td>3 (10.3)</td><td>17 (9.9)</td><td></td></tr><tr><td> 16-20</td><td>0 (0.0)</td><td>15 (8.8)</td><td></td></tr><tr><td> >20</td><td>0 (0.0)</td><td>6 (3.5)</td><td></td></tr><tr><td><i>Ever had Blood transfusion</i>?</td><td></td><td></td><td>0.472</td></tr><tr><td> Yes</td><td>0 (0.0)</td><td>3 (1.8)</td><td></td></tr><tr><td> No</td><td>29 (100)</td><td>168 (98.2)</td><td></td></tr><tr><td colspan="2"><i>Ever undergone dental procedure</i>?</td><td></td><td>0.259</td></tr><tr><td> Yes</td><td>1 (3.4)</td><td>17 (9.9)</td><td></td></tr><tr><td> No</td><td>28 (96.6)</td><td>154 (90.1)</td><td></td></tr><tr><td><i>Tattoo</i>/<i>Body piercing</i></td><td></td><td></td><td>0.448</td></tr><tr><td> Yes</td><td>3 (10.3)</td><td>27 (15.8)</td><td></td></tr><tr><td> No</td><td>26 (89.7)</td><td>144 (84.2)</td><td></td></tr><tr><td><i>Use of IV drugs</i></td><td></td><td></td><td>0.214</td></tr><tr><td> Yes</td><td>4 (13.8)</td><td>12 (7.0)</td><td></td></tr><tr><td> No</td><td>25 (86.2)</td><td>159 (93.0)</td><td></td></tr><tr><td colspan="2"><i>Ever had unprotected sex before</i>?</td><td></td><td>0.779</td></tr><tr><td> Yes</td><td>24 (82.8)</td><td>145 (84.8)</td><td></td></tr><tr><td> No</td><td>5 (17.2)</td><td>26 (15.2)</td><td></td></tr><tr><td><i>Vaccinated for Hepatitis B</i></td><td></td><td></td><td>0.182</td></tr><tr><td> Yes</td><td>0 (0.0)</td><td>10 (5.8)</td><td></td></tr><tr><td> No</td><td>29 (100)</td><td>161 (94.2)</td><td></td></tr></table> |
fdc1dcdea2a64e88bc579be1fb3e8793dc0bd87aae7241023a327a8d8ddcbda7.png | complex | <table><tr><td rowspan="3"></td><td rowspan="2" colspan="2">All</td><td colspan="6">SUDOSCAN Risk Score</td><td><i>p</i></td></tr><tr><td colspan="2">No Risk</td><td colspan="2">Moderate Risk</td><td colspan="2">Elevated Risk</td><td></td></tr><tr><td>Mean</td><td>SD</td><td>Mean</td><td>SD</td><td>Mean</td><td>SD</td><td>Mean</td><td>SD</td><td></td></tr><tr><td>Women</td><td colspan="2"><i>n</i>=537</td><td colspan="2"><i>n</i>=162</td><td colspan="2"><i>n</i>=188</td><td colspan="2"><i>n</i>=187</td><td></td></tr><tr><td>Age (years)</td><td>49.7</td><td>8.3</td><td>42.8</td><td>7.8</td><td>51.3</td><td>6.3</td><td>54.0</td><td>6.7</td><td><0.0001</td></tr><tr><td>BMI (kg/m<sup>2</sup>)</td><td>25.9</td><td>4.5</td><td>23.2</td><td>2.8</td><td>25.0</td><td>3.2</td><td>29.1</td><td>4.9</td><td><0.0001</td></tr><tr><td>Weight (kg)</td><td>69.7</td><td>12.9</td><td>63.5</td><td>8.7</td><td>66.9</td><td>9.5</td><td>77.9</td><td>14.7</td><td><0.0001</td></tr><tr><td>Waist (cm)</td><td>88.6</td><td>12.2</td><td>81.3</td><td>8.5</td><td>86.6</td><td>9.1</td><td>96.7</td><td>12.9</td><td><0.0001</td></tr><tr><td>Body fat (%)</td><td>33.9</td><td>6.9</td><td>29.5a</td><td>5.7</td><td>33.0</td><td>5.7</td><td>38.7b</td><td>5.9</td><td><0.0001*</td></tr><tr><td>SBP (mm Hg)</td><td>138</td><td>19</td><td>132</td><td>17</td><td>139</td><td>19</td><td>142</td><td>20</td><td><0.0001</td></tr><tr><td>DBP (mm Hg)</td><td>89</td><td>11</td><td>86</td><td>10</td><td>89</td><td>11</td><td>92</td><td>10</td><td><0.0001</td></tr><tr><td>HbA<sub>1C</sub> (%)<sup>&</sup></td><td>5.7</td><td>0.4</td><td>5.5a</td><td>0.4</td><td>5.7</td><td>0.3</td><td>6.9</td><td>0.4</td><td><0.0001*</td></tr><tr><td>Estimated VO<sub>2</sub>max (METs)<sup>&&</sup></td><td>9.1</td><td>1.8</td><td>10.3</td><td>1.7</td><td>9.0</td><td>1.5</td><td>7.9b</td><td>1.2</td><td><0.0001*</td></tr><tr><td>Hand ESC (μS)</td><td>70.0</td><td>10.0</td><td>74.0</td><td>9.0</td><td>71.0</td><td>10.0</td><td>66.0</td><td>11.0</td><td><0.0001*</td></tr><tr><td>Foot ESC (μS)</td><td>81.0</td><td>8.0</td><td>86.0</td><td>4.0</td><td>82.0</td><td>6.0</td><td>76.0</td><td>9.0</td><td><0.0001*</td></tr><tr><td>Men</td><td colspan="2"><i>n</i>=113</td><td colspan="2"><i>n</i>=31</td><td colspan="2"><i>n</i>=48</td><td colspan="2"><i>n</i>=34</td><td></td></tr><tr><td>Age (years)</td><td>51.2</td><td>8.2</td><td>44.4</td><td>9.4</td><td>51.9</td><td>5.8</td><td>56.5</td><td>5.1</td><td><0.0001</td></tr><tr><td>BMI (kg/m<sup>2</sup>)</td><td>25.9</td><td>3.5</td><td>23.3</td><td>2.5</td><td>25.9</td><td>2.7</td><td>28.3</td><td>3.7</td><td><0.0001</td></tr><tr><td>Weight (kg)</td><td>81.8</td><td>12.8</td><td>74.9</td><td>11.9</td><td>81.2</td><td>10.1</td><td>88.9</td><td>13.4</td><td><0.0001</td></tr><tr><td>Waist (cm)</td><td>95.3</td><td>11.0</td><td>86.8</td><td>8.2</td><td>95.5</td><td>8.7</td><td>102.9</td><td>10.6</td><td><0.0001</td></tr><tr><td>Body fat (%)</td><td>21.3</td><td>5.9</td><td>16.7</td><td>4.7</td><td>21.4</td><td>4.8</td><td>25.2</td><td>5.6</td><td><0.0001</td></tr><tr><td>SBP</td><td>149</td><td>19</td><td>148</td><td>15</td><td>146</td><td>16</td><td>155</td><td>25</td><td>NS</td></tr><tr><td>DBP</td><td>92</td><td>11</td><td>91</td><td>9</td><td>93</td><td>11</td><td>93</td><td>14</td><td>NS</td></tr><tr><td>HbA<sub>1C</sub> (%)</td><td>6.2</td><td>1.0</td><td>5.7</td><td>0.2</td><td>6.4</td><td>1.5</td><td>6.3</td><td>0.8</td><td>-</td></tr><tr><td>Estimated VO<sub>2</sub>max (METs)<sup>&&</sup></td><td>12.2</td><td>2.5</td><td>13.9</td><td>2.4</td><td>12.1</td><td>2.3</td><td>10.4</td><td>1.9</td><td><0.0001</td></tr><tr><td>Hand ESC (μS)</td><td>69.0</td><td>11.0</td><td>75.0</td><td>6.0</td><td>69.0</td><td>11.0</td><td>65.0b</td><td>12.0</td><td>0.0003*</td></tr><tr><td>Foot ESC (μS)</td><td>83.0</td><td>5.0</td><td>86.0</td><td>4.0</td><td>84.0</td><td>4.0</td><td>80.0</td><td>6.0</td><td><0.0001*</td></tr></table> |
b53e01d21e015e326240feac6921a3564d71f12d5ab177f5cc9e1197ee38c9ab.png | simple | <table><tr><td>Characteristics</td><td>Feminized Male CRC (Total = 26) No. (%)</td><td>Non-Feminized Male CRC (Total = 31) No. (%)</td><td>Total Males (Total = 57) No. (%)</td><td><i>p</i>-Value</td></tr><tr><td>MSS—wild type <i>BRAF</i></td><td>24 (92.3)</td><td>17 (56.7)</td><td>41 (72.0)</td><td>0.0026 *</td></tr><tr><td>Wild-type <i>BRAF</i></td><td>26 (100)</td><td>23 (74.2)</td><td>49 (86.0)</td><td>0.0088 *</td></tr><tr><td>MMR proficient</td><td>24 (92.3)</td><td>19 (61.2)</td><td>43 (75.4)</td><td>0.0107 *</td></tr></table> |
98871f9516062c6a63158e51c0bc095827730a0bc2263855533d2a250158384e.png | complex | <table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td colspan="2">Prior Probability of Mutation in a <i>BRCA </i>gene</td></tr><tr><td>Case #</td><td>Cancer diagnosis (index-case)</td><td>Age at diagnosis (ys)</td><td>Cancer family history*</td><td>ASCO criteria</td><td>Limited Family Structure</td><td>Myriad Prevalence Tables (%)</td><td>Couch Prediction Model (%)</td></tr><tr><td>1-RJ</td><td>Breast</td><td>33</td><td>MAT Br (F-45)</td><td>Yes</td><td>No</td><td>16.3</td><td>20.0</td></tr><tr><td>2-RJ</td><td>Ovarian</td><td>47</td><td>PAT Ov (60), Br (F-30), End (64)</td><td>Yes</td><td>No</td><td>46.8</td><td>44.0</td></tr><tr><td>3-RS</td><td>Ovarian</td><td>52</td><td>MAT Br (F-44), Ov (F-76), Ov (F-66), Ut (F-78), Ut (N/A), Ga (M-68),CRC (M-69), HeN (M-N/A), HeN (M-75)</td><td>No</td><td>No</td><td>46.8</td><td>43.0</td></tr><tr><td></td><td></td><td></td><td>PAT Lu (M-N/A), CRC (M-N/A), CRC (F-N/A), Ut (35), Br (M-62), Ga (M-N/A), Br (F-36), Bilat Br (F-45), Br (F-44), Br (F-45)</td><td>Yes</td><td>No</td><td>40.8</td><td>33.0</td></tr><tr><td>4-RJ</td><td>Bilateral Breast</td><td>45 and 50</td><td>MAT BilatBr (F-45,50), Ov (39) Br (F-49), Bilat Br (F-47,50)</td><td>Yes</td><td>No</td><td>40.7</td><td>31.0</td></tr><tr><td>5-RJ</td><td>Bilateral Breast</td><td>46 and 47</td><td>PAT Lu (M-N/A), Ga (M-N/A) CRC (M-N/A)</td><td>No</td><td>Yes</td><td>6.9</td><td>9.0</td></tr><tr><td>6-RJ</td><td>Bilateral Breast</td><td>33 and 38</td><td>-</td><td>No</td><td>Yes</td><td>6.9</td><td>15.0</td></tr><tr><td>7-RS</td><td>Bilateral Breast</td><td>35 and 45</td><td>MAT Ov (F-58), Ov (F-49), Br (F-90) Br (F-49), Ga (M-70), Liv (M-70)</td><td>Yes</td><td>No</td><td>40.7</td><td>47.0</td></tr></table> |
b893fa89ec6536aee33d84420d37c161d1593ffade0d9a5e4f3aca9fae2d2eeb.png | simple | <table><tr><td>Oligo ID</td><td>Gene</td><td>Purpose</td><td>Sequences (5' to 3')</td></tr><tr><td>swcM1</td><td>M</td><td>capture</td><td>CTGACTAAGGGAATTTTAGGATTTGTGTTCACGCTCACCG</td></tr><tr><td>swcM2</td><td>M</td><td>capture</td><td>TGATTCACAGCATCGGTCTCACAGACAGATGGCTACTACC</td></tr><tr><td>swcM3</td><td>M</td><td>capture</td><td>AAGGCTATGGAACAGATGGCTGGATCGAGTGAACAGGCAG</td></tr><tr><td>swcH1</td><td>HA</td><td>capture</td><td>GAAGGCAATACTAGTAGTTCTGCTATATACATTTGCAACC</td></tr><tr><td>swcH2</td><td>HA</td><td>capture</td><td>CCTGGGAAATCCAGAGTGTGAATCACTCTCCACAGCAAGC</td></tr><tr><td>swcH3</td><td>HA</td><td>capture</td><td>GTTTTTGTGGGGTCATCAAGATACAGCAAGAAGTTCAAGC</td></tr><tr><td>swcH4</td><td>HA</td><td>capture</td><td>GAAGCAAAATTAAACAGAGAAGAAATAGATGGGGTAAAGC</td></tr><tr><td>swcN1</td><td>NA</td><td>capture</td><td>TTCGGTCTGTATGACAATTGGAATGGCTAACTTAATATTA</td></tr><tr><td>swcN2</td><td>NA</td><td>capture</td><td>GTGGTTTCCGTGAAATTAGCGGGCAATTCCTCTCTCTGCC</td></tr><tr><td>swcN3</td><td>NA</td><td>capture</td><td>CAATGGAACCATTAAAGACAGGAGCCCATATCGAACCCTA</td></tr><tr><td>swcN4</td><td>NA</td><td>capture</td><td>ACGCCCTAATGATAAGACAGGCAGTTGTGGTCCAGTATCG</td></tr><tr><td>swiM1</td><td>M</td><td>intermediate</td><td>AAAGCCGAGATCGCGCAGAGACTGGAAAGTGTCTTTGCAG *</td></tr><tr><td>swiM2</td><td>M</td><td>intermediate</td><td>CCACTAATCAGGCATGAAAACAGAATGGTGCTGGCTAGCA *</td></tr><tr><td>swiM3</td><td>M</td><td>intermediate</td><td>GCCTGAGTCCATGAGGGAAGAATATCAACAGGAACAGCAG *</td></tr><tr><td>swiM4</td><td>M</td><td>intermediate</td><td>AATGGGAGTGCAGATGCAGCGATTCAAGTGATCCTCTCGT *</td></tr><tr><td>swiH1</td><td>HA</td><td>intermediate</td><td>AAGACAAGCATAACGGGAAACTATGCAAACTAAGAGGGGT *</td></tr><tr><td>swiH2</td><td>HA</td><td>intermediate</td><td>GTGGAAACACCTAGTTCAGACAATGGAACGTGTTACCCAG *</td></tr><tr><td>swiH3</td><td>HA</td><td>intermediate</td><td>AAACGGCTGCTTTGAATTTTACCACAAATGCGATAACACG *</td></tr><tr><td>swiN1</td><td>NA</td><td>intermediate</td><td>CTTGGGAATCAAAATCAGATTGAAACATGCAATCAAAGCG *</td></tr><tr><td>swiN2</td><td>NA</td><td>intermediate</td><td>GTAAAGACAACAGTGTAAGAATCGGTTCCAAGGGGGATGT*</td></tr><tr><td>swiN3</td><td>NA</td><td>intermediate</td><td>CAGTCGCTTGGTCAGCAAGTGCTTGTCATGATGGCATCAA *</td></tr><tr><td>swiN4</td><td>NA</td><td>intermediate</td><td>TACGGCAATGGTGTTTGGATAGGGAGAACTAAAAGCATTA *</td></tr><tr><td>ABI04mF</td><td>M</td><td>PCR</td><td>TAACCGAGGTCGAAACGTA</td></tr><tr><td>ABI04mR</td><td>M</td><td>PCR</td><td>TTACTCTAGCTCTATGTTGACAAA</td></tr><tr><td>ABI05hF</td><td>HA</td><td>PCR</td><td>ATGAAGGCAATACTAGTAGTTCTGCT</td></tr><tr><td>ABI05hR</td><td>HA</td><td>PCR</td><td>TTCTACACTGTAGAGACCCATTAG</td></tr><tr><td>ABI06nF</td><td>NA</td><td>PCR</td><td>ATGAATCCAAACCAAAAGATAATAA</td></tr><tr><td>ABI06nR</td><td>NA</td><td>PCR</td><td>TTACTTGTCAATGGTAAATGGCAACT</td></tr></table> |
093b4f2fd993b652f4384022d40477d90d0cfa6a2802bc57eaf61e523e1ef4f7.png | simple | <table><tr><td>Clinical guidelines directly related to the practice of dentistry</td><td>No.</td></tr><tr><td>American Dental Association</td><td>2</td></tr><tr><td>American Academy of Pediatric Dentistry</td><td>22</td></tr><tr><td>American Cleft Palate Craniofacial Association</td><td>1</td></tr><tr><td>American Academy of Pediatrics</td><td>1</td></tr><tr><td>American Academy of Sleep Apnea</td><td>1</td></tr><tr><td>Center for Disease Control</td><td>1</td></tr><tr><td>US Preventive Services Task Force</td><td>2</td></tr><tr><td>New York State Department of Health</td><td>2</td></tr><tr><td>Health Partners</td><td>4</td></tr><tr><td>University of Texas at Austin</td><td>1</td></tr><tr><td>Non US Government Agencies</td><td>8</td></tr><tr><td>Areas covered by other stomatognathic clinical guidelines</td><td></td></tr><tr><td>Preventive Services</td><td>12</td></tr><tr><td>Cancer</td><td>3</td></tr><tr><td>Infectious Diseases</td><td>7</td></tr><tr><td>TOTAL</td><td>67</td></tr></table> |
57816b4cfb393c133e9e7de03e34cb2d81469513a92181c5896cbd6907e2d305.png | simple | <table><tr><td>Age group</td><td>Outcome</td><td>Indicator</td><td>Measurement tool</td></tr><tr><td>Adults</td><td>Healthy eating*</td><td>Binary: consumption of five or more portions of fruit and vegetables per day (‘five-a-day’)</td><td>Food frequency questionnaire</td></tr><tr><td>Adults</td><td>Healthy physical activity*</td><td>Binary: doing five or more sessions of moderate intensity physical activity per week lasting at least 30 min (‘five-a-week’)</td><td>International Physical Activity Questionnaire</td></tr><tr><td>Adults</td><td>Mental wellbeing - positive</td><td>Continuous: Hope Scale score</td><td>Hope Scale</td></tr><tr><td>Adults</td><td>Mental wellbeing - negative</td><td>Binary: reports feeling anxious or depressed</td><td>EQ5D (1 item)</td></tr><tr><td>Adults</td><td>Mental wellbeing - negative</td><td>Binary: reports visiting GP for anxiety or depression or other emotional problem</td><td>Individual questionnaire item</td></tr><tr><td>Adolescents</td><td>Healthy eating - positive</td><td>Binary: frequent consumption of fruit</td><td>Individual questionnaire item</td></tr><tr><td>Adolescents</td><td>Healthy eating negative</td><td>Continuous: score summarizing frequency of consumption of chips, sweets or chocolate, and s ugar sweetened soft drinks<sup>b</sup></td><td>Individual questionnaire items</td></tr><tr><td>Adolescents</td><td>Healthy physical activity*</td><td>Continuous: IPAQ score</td><td>Physical Activity Questionnaire for Adolescents</td></tr><tr><td>Adolescents</td><td>Mental health - negative*</td><td>Binary: score above threshold for normal mental health</td><td>Strengths and Difficulties Questionnaire</td></tr><tr><td>Adolescents</td><td>Mental health - positive wellbeing*</td><td>Continuous: positive affect score and negative affect score</td><td>Positive and negative affect scale</td></tr></table> |
9ce17ec8d14671020c5bf71f4ad359d332a0b8d187b36ad5a348396c652f4a74.png | simple | <table><tr><td></td><td></td><td>Pre Meeting</td><td>Meeting</td><td>Test</td></tr><tr><td>Gender</td><td><i>Males</i></td><td>27</td><td>24</td><td>NS</td></tr><tr><td></td><td><i>Females</i></td><td>7</td><td>9</td><td></td></tr><tr><td>Age</td><td><i>(av +/- sd)</i></td><td>46.6 +/- 8.6</td><td>44.5 +/- 9.3</td><td>NS</td></tr><tr><td>Experience</td><td><i>(av +/- sd)</i></td><td>18.3 +/- 10.6</td><td>18.3 +/- 10.3</td><td>NS</td></tr><tr><td>Braces/y</td><td><i>(med – 95% IC)</i></td><td>150 (30–965)</td><td>200 (28–1725)</td><td>NS</td></tr><tr><td></td><td><i>Less than 100</i></td><td>8</td><td>5</td><td></td></tr><tr><td></td><td>100–300</td><td>15</td><td>12</td><td></td></tr><tr><td></td><td><i>Over 300</i></td><td>5</td><td>9</td><td></td></tr><tr><td>Profession</td><td><i>MD-OS</i></td><td>12</td><td>9</td><td>NS</td></tr><tr><td></td><td><i>MD-PRM</i></td><td>6</td><td>9</td><td></td></tr><tr><td></td><td><i>CPO</i></td><td>5</td><td>8</td><td></td></tr><tr><td></td><td><i>PT</i></td><td>9</td><td>7</td><td></td></tr><tr><td></td><td><i>Oth</i></td><td>2</td><td>2</td><td></td></tr></table> |
192168c908cb0365115cdc2e72684481b825fec1067611f09c7da75c1febb68b.png | simple | <table><tr><td></td><td>PR n=15</td><td>GR n=15</td><td><i>p</i> Value</td></tr><tr><td>Age: mean (SD)</td><td>59.1 (7.2)</td><td>51.7 (10.8)</td><td>0.04*</td></tr><tr><td>Gender, number of patients: M (F)</td><td>10 (5)</td><td>8 (7)</td><td>0.46**</td></tr><tr><td>Time since stroke: mean (SD) and range (months)</td><td>40.7 (42.6) 6–165</td><td>31.3 (28.2) 6–116</td><td>0.74*</td></tr><tr><td>Ratio of ischaemic to primary intracerebral haemorrhagic stroke</td><td>12:3</td><td>13:2</td><td>–</td></tr><tr><td>ARAT: mean (SD) (max 57)</td><td>32.9 (8.5)</td><td>52.7 (5.49)</td><td><0.01*</td></tr><tr><td>Grip mean: (SD) (% unaffected side)</td><td>41.4 (14.3)</td><td>74.6 (18.57)</td><td><0.01*</td></tr><tr><td>Motricity index: mean (SD) (% unaffected side)</td><td>65.2 (11.4)</td><td>91.9 (4.2)</td><td><0.01*</td></tr><tr><td>NHPT: mean (SD) (% unaffected side)</td><td>5.8 (5.9)</td><td>53.1 (23.7)</td><td><0.01*</td></tr></table> |
4976c6e49e2e2d21bc85104025c5ae65af0be943790bd64f69426fbb96d76854.png | simple | <table><tr><td></td><td>PFOS</td><td>PFOA</td><td>PFAA sumb</td></tr><tr><td>Testosterone</td><td>−0.087 (−0.32 to 0.15)</td><td>−0.98 (−2.33 to 0.37)</td><td>−0.093 (−0.303 to 0.116)</td></tr><tr><td>lnEstradiol</td><td>−0.001 (−0.008 to 0.005)</td><td>−0.012 (−0.051 to 0.027)</td><td>−0.001 (−0.007 to 0.005)</td></tr><tr><td>lnSHBG</td><td>0.002 (−0.007 to 0.012)</td><td>−0.009 (−0.067 to 0.048)</td><td>0.002 (−0.007 to 0.011)</td></tr><tr><td>lnLH</td><td>0.000 (−0.014 to 0.012)</td><td>−0.010 (−0.084 to 0.064)</td><td>0.000 (−0.012 to 0.010)</td></tr><tr><td>lnFSH</td><td>0.004 (−0.13 to 0.22)</td><td>−0.037 (−0.14 to 0.064)</td><td>0.003 (−0.013 to 0.018)</td></tr><tr><td>lnInhibin B</td><td>−0.004 (−0.21 to 0.12)</td><td>0.012 (−0.084 to 0.11)</td><td>−0.003 (−0.018 to 0.012)</td></tr><tr><td>lnFAI</td><td>−0.006 (−0.015 to 0.002)</td><td>−0.038 (−0.087 to 0.011)</td><td>−0.006 (−0.014 to 0.001)</td></tr><tr><td>lnTestosterone/LH</td><td>−0.003 (−0.017 to 0.011)</td><td>−0.037 (−0.12 to 0.045)</td><td>−0.003 (−0.016 to 0.009)</td></tr><tr><td>lnFAI/LH</td><td>−0.006 (−0.020 to 0.009)</td><td>−0.028 (−0.114 to 0.058)</td><td>−0.005 (−0.018 to 0.008)</td></tr><tr><td>lnEstradiol/testosterone</td><td>0.003 (−0.005 to 0.010)</td><td>0.035 (−0.010 to 0.081)</td><td>0.003 (−0.004 to 0.010)</td></tr><tr><td>lnInhibin/FSH</td><td>−0.009 (−0.039 to 0.022)</td><td>0.049 (−0.13 to 0.23)</td><td>−0.006 (−0.034 to 0.022)</td></tr></table> |
3d8f871da57a43c186a601d70c77a4daa66012f68c9aa8d4573bc1665eeee82c.png | simple | <table><tr><td>Characteristics</td><td>Patient 1</td><td>Patient 2</td></tr><tr><td>Age at first visit to fertility clinic</td><td>28 years</td><td>31 years</td></tr><tr><td>Pubarche (spontaneous)</td><td>at 14 years</td><td>at 15 years</td></tr><tr><td>Heights</td><td>170 cm</td><td>156 cm</td></tr><tr><td>Weight</td><td>65 kg</td><td>53 kg</td></tr><tr><td>Breast development by Tanner scale</td><td>Stage V</td><td>Stage IV</td></tr><tr><td>Sense of odors</td><td>Normal</td><td>Normal</td></tr><tr><td>Karyotype</td><td>46, XX</td><td>46, XX</td></tr><tr><td>MRI of the pituitary</td><td><i>Size:</i> 10 mm x 6 mm x16 mm. Signs of signal reduction in the right half of the posterior pituitary (4 mm x 3 mm x 2 mm), depicting a cyst.</td><td><i>Size:</i> 3.5 mm x 5 mm x 9 mm showing signs of moderate pituitary hypoplasia</td></tr><tr><td>Vaginal ultrasound</td><td><i>Uterus:</i> 27 mm x 43 mm x 30 mm<i>Endometrium:</i> 2.3 mm<i>Right ovary:</i> 18 mm x 16 mm with 4 follicles (6 to 8 mm).<i>Left ovary:</i> 17 mm x 18 mm with 5 follicles (6 to 7 mm).Moderate hypoplasia of the uterus and ovaries.</td><td><i>Uterus:</i> 35 mm x 22 mm x30 mm<i>Endometrium:</i> 1.8 mm<i>Right ovary:</i> 21 mm x 18 mm with 3 follicles (3 to 5 mm)<i>Left ovary:</i> 17 mm x 18 mm with 5 follicles (6 to 7 mm). Moderate hypoplasia of the ovaries.</td></tr><tr><td>Partner characteristics for IVF with ICSI</td><td><i>Ejaculate volume:</i> 2 ml<i>Sperm concentration:</i> 39x10<sup>6</sup>/ml,<i>Motile sperms:</i> 3 %<i>Normal forms by Kruger strict criteria:</i> 2 %.</td><td><i>Ejaculate volume:</i> 5 ml<i>Sperm concentration:</i> 31x10<sup>6</sup>/ml<i>Motile sperms:</i> None<i>Normal forms by Kruger strict criteria:</i> 1 %.</td></tr></table> |
0802ea6f1df5e55f16e802d0e1b76c6863b4cffe9244d323cf23e4d12f4f8f31.png | simple | <table><tr><td>Parameter</td><td>PA (<i>n</i> = 30)</td><td>EH (<i>n</i> = 31)</td><td><i>p</i></td></tr><tr><td>Age (years)</td><td>55 ± 11</td><td>54 ± 10</td><td>NS</td></tr><tr><td>Gender (male/female)</td><td>8/22</td><td>16/14</td><td>NS</td></tr><tr><td>Body mass index (kg/m<sup>2</sup>)</td><td>26.9 ± 4</td><td>25.1 ± 3</td><td>NS</td></tr><tr><td>SBP/DBP</td><td>135 ± 17/82 ± 10</td><td>129 ± 11/79 ± 6</td><td>NS/NS</td></tr><tr><td>Heart rate (bpm)</td><td>70 ± 10</td><td>70 ± 8</td><td>NS</td></tr><tr><td>Glycemia (mg/dL)</td><td>92 ± 13</td><td>94 ± 18</td><td>NS</td></tr><tr><td>Metabolic syndrome</td><td>11/30</td><td>8/31</td><td>NS</td></tr><tr><td>Serum K<sup>+</sup> (mEq/dL)</td><td>3.99 ± 0.68</td><td>4.27 ± 0.37</td><td><0.05</td></tr><tr><td>Creatinine (mg/dL)</td><td>1 ± 0.19</td><td>0.86 ± 0.15</td><td><0.001</td></tr><tr><td>PAC (ng/dl)</td><td>426 ± 422</td><td>104 ± 60</td><td><0.0001</td></tr><tr><td>PAC/PRA (ng/dl:ng/ml/h)</td><td>84.3 ± 79</td><td>17.6 ± 15</td><td><0.00002</td></tr></table> |
131829b4a8382018cd7ec159a10751e254e0966dd6d2d25218c82afb0f3bb596.png | simple | <table><tr><td>2nd AI</td><td>Number of records</td><td>Embryonic mortality rate (%)</td></tr><tr><td>18–29 D</td><td>769,103</td><td>23.00</td></tr><tr><td>30–60 D</td><td>592,243</td><td>21.97</td></tr><tr><td>61–90 D</td><td>462,098</td><td>16.91</td></tr><tr><td>91–140 D</td><td>383,979</td><td>8.47</td></tr><tr><td>141 D–parturition</td><td>351,455</td><td>3.30</td></tr></table> |
a50071f226715e30a078b1d5b64dd0356a7769d2df346aadf10f9e126291dd1c.png | simple | <table><tr><td>Age</td><td>Gender</td><td>Handedness</td><td>Brain areas with Foci</td></tr><tr><td>38</td><td>Male</td><td>Right</td><td>Right temporal lobe</td></tr><tr><td>54</td><td>Female</td><td>Right</td><td>Left amygdala, left hippocampus, right hippocampus</td></tr><tr><td>42</td><td>Male</td><td>Right</td><td>Left amygdala, left hippocampus</td></tr><tr><td>35</td><td>Male</td><td>Left</td><td>Right amygdala, right hippocampus</td></tr><tr><td>41</td><td>Male</td><td>Right</td><td>Left hippocampus, left frontal lobe</td></tr><tr><td>21</td><td>Female</td><td>Right</td><td>Left amygdala, left hippocampus</td></tr><tr><td>24</td><td>Female</td><td>Right</td><td>Right amygdala, right hippocampus, right frontal lobe</td></tr><tr><td>23</td><td>Male</td><td>Right</td><td>Right amygdala, right hippocampus</td></tr><tr><td>54</td><td>Female</td><td>Right</td><td>Left hippocampus</td></tr><tr><td>56</td><td>Female</td><td>Right</td><td>Right occipetal lobe</td></tr><tr><td>40</td><td>Female</td><td>Right</td><td>Right amygdala, right hippocampus</td></tr><tr><td>54</td><td>Female</td><td>Right</td><td>Right hippocampus</td></tr><tr><td>20</td><td>Male</td><td>Right</td><td>Right temporal lobe</td></tr><tr><td>53</td><td>Female</td><td>Right</td><td>Right amygdala, right hippocampus, left amygdala, left hippocampus</td></tr></table> |
aaf854461c6a3fc309077acdadbd98dc7f6f62ac7999bf9160114257e40e28ca.png | simple | <table><tr><td>Sampling subjects</td><td>Source of sample</td><td>Number of sample screened</td><td>Positive samples on microbiological analysis</td><td>Positive samples on biochemical analysis</td><td>Genus specific PCR positive</td><td>Serotype identified by multiplex PCR</td></tr><tr><td>Human infants (<5 years)</td><td>Male</td><td>200</td><td>23</td><td>2</td><td>2</td><td><i>Salmonella</i> Enteritidis (n=1), other <i>Salmonella</i> serotypes (n=1)</td></tr><tr><td></td><td>Female</td><td>200</td><td>30</td><td>3</td><td>3</td><td><i>Salmonella</i> Enteritidis (n=1), <i>Salmonella</i> Typhimurium (n=2)</td></tr><tr><td>Young animals (<6 months)</td><td>Canine</td><td>25</td><td>8</td><td>2</td><td>2</td><td>Other <i>Salmonella</i> serotypes (n=2)</td></tr><tr><td></td><td>Bovine</td><td>15</td><td>3</td><td>0</td><td>0</td><td>ND</td></tr><tr><td></td><td>Equine</td><td>10</td><td>0</td><td>0</td><td>0</td><td>ND</td></tr><tr><td>Fresh vegetables</td><td>Cilantro leaves</td><td>10</td><td>5</td><td>1</td><td>1</td><td><i>Salmonella</i> Typhimurium (n=1)</td></tr><tr><td></td><td>Tomato</td><td>20</td><td>3</td><td>1</td><td>1</td><td>Other <i>Salmonella</i> serotypes (n=1)</td></tr><tr><td></td><td>Mint leaves</td><td>20</td><td>0</td><td>0</td><td>0</td><td>ND</td></tr><tr><td>Sewage waste</td><td></td><td>50</td><td>20</td><td>5</td><td>5</td><td>Other <i>Salmonella</i> serotypes (n=5)</td></tr></table> |
126b2fa24cc5798117107415a8847de3e95e14c6f6726c689621b02bb2cfaa20.png | simple | <table><tr><td> </td><td>Waca Playa (Bolivia)</td><td>Pitumarca (Peru)</td></tr><tr><td>Human Development Index</td><td>0.36 <sup>a</sup></td><td>0.51 <sup>b</sup></td></tr><tr><td>Life expectancy (years)</td><td>52.4 <sup>a</sup></td><td>70.0 <sup>b</sup></td></tr><tr><td>National social health security</td><td>SUMI: coverage for pregnant women and children under age 5</td><td>SIS: coverage for all adult population living in poverty or extreme poverty</td></tr><tr><td>Community biomedical facilities</td><td>Rudimentary medical post with one auxiliary nurse provides ambulatory health care to 20 villages. Approximately one visit by auxiliary nurse every two months to each village.<sup>c</sup></td><td>Health center with 11 health professionals, including one medical doctor. One visit by a nurse per month to each village. 4 to 6 health workers trained in each village. <sup>c</sup></td></tr><tr><td>Distance from community to villages where households were interviewed (km)</td><td>5 to 9 <sup>c</sup></td><td>4 to 5 <sup>c</sup></td></tr><tr><td>Distance from community to nearest hospital (km)</td><td>approximately 40 (dirt road) <sup>c</sup></td><td>35 (paved road) <sup>c</sup></td></tr><tr><td>Beds per inhabitant (number)</td><td>0.66 <sup>d</sup></td><td>0.84 <sup>e</sup></td></tr></table> |
a39ab10205a0587e1f7ab1f3d69472bc29e841cd9668cda8dce5c582db03952c.png | simple | <table><tr><td>Subpopulation</td><td><i>k</i><sub>o</sub> (h<sup>−1</sup>)</td><td><i>k</i><sub>d</sub> (h<sup>−1</sup>)</td><td><i>k</i><sub>o</sub>/<i>k</i><sub>d</sub></td></tr><tr><td>Virgin females</td><td>0.063 ± 0.003</td><td>0.055 ± 0.003</td><td>1.16</td></tr><tr><td>Virgin males</td><td>0.065 ± 0.005</td><td>0.055 ± 0.004</td><td>1.18</td></tr><tr><td>Once-mated females</td><td>0.067 ± 0.004</td><td>0.058 ± 0.004</td><td>1.18</td></tr><tr><td>Once-mated males</td><td>0.062 ± 0.004</td><td>0.053 ± 0.003</td><td>1.18</td></tr><tr><td>Mixed-sex group: females</td><td>0.095 ± 0.007</td><td>0.084 ± 0.006</td><td>1.12</td></tr><tr><td>Mixed-sex group: males</td><td>0.099 ± 0.011</td><td>0.087 ± 0.008</td><td>1.14</td></tr><tr><td>Mean</td><td>0.072 ± 0.003</td><td>0.062 ± 0.003</td><td></td></tr></table> |
4c71f8301d11c62ab8c298a8debe73f55e3d1492a7e579a9280cede922178a46.png | simple | <table><tr><td></td><td>Step 1</td><td>Step 2</td><td>Step 3</td><td>Step 4</td><td>Step 5</td><td>Step 6</td><td>Step 7</td></tr><tr><td># Minigaps</td><td>27</td><td>27</td><td>15</td><td>13</td><td>1</td><td>0</td><td>0</td></tr><tr><td>Assembled nt in the big gap</td><td>0</td><td>0</td><td>12,511</td><td>12,511</td><td>12,511</td><td>35,746</td><td>35,746</td></tr><tr><td>Total nt assembled*</td><td>1,808,353</td><td>1,808,353</td><td>1,828,147</td><td>1,828,363</td><td>1,832,588</td><td>1,851,716</td><td>1,851,618</td></tr></table> |
9bbc78ccc2c46b50b89e234598edab687c84074c19c1e62641be8e3f80cc8f42.png | simple | <table><tr><td></td><td>Subjects</td><td>Mild</td><td>Moderate</td><td>Severe</td><td>Not related</td><td>Possibly related</td><td>Probably related</td><td>Definitely related</td></tr><tr><td>Overall</td><td>120 (71.9)</td><td>61 (36.5)</td><td>50 (29.9)</td><td>9 (5.4)</td><td>32 (19.2)</td><td>9 (5.4)</td><td>19 (11.4)</td><td>60 (35.9)</td></tr><tr><td>Application site pain</td><td>51 (30.5)</td><td>38 (22.8)</td><td>12 (7.2)</td><td>1 (0.6)</td><td>0</td><td>2 (1.2)</td><td>9 (5.4)</td><td>40 (24.0)</td></tr><tr><td>Dysgeusia</td><td>35 (21.0)</td><td>30 (18.0)</td><td>5 (3.0)</td><td>0</td><td>0</td><td>4 (2.4)</td><td>7 (4.2)</td><td>24 (14.4)</td></tr><tr><td>Application site reaction</td><td>9 (5.4)</td><td>7 (4.2)</td><td>2 (1.2)</td><td>0</td><td>0</td><td>1 (0.6)</td><td>2 (1.2)</td><td>6 (3.6)</td></tr><tr><td>Application site irritation</td><td>7 (4.2)</td><td>7 (4.2)</td><td>0</td><td>0</td><td>0</td><td>1 (0.6)</td><td>0</td><td>6 (3.6)</td></tr><tr><td>Throat irritation</td><td>8 (4.8)</td><td>6 (3.6)</td><td>2 (1.2)</td><td>0</td><td>0</td><td>1 (0.6)</td><td>2 (1.2)</td><td>5 (3.0)</td></tr><tr><td>Chest discomfort</td><td>4 (2.4)</td><td>4 (2.4)</td><td>0</td><td>0</td><td>1 (0.6)</td><td>0</td><td>0</td><td>3 (1.8)</td></tr><tr><td>Nausea</td><td>7 (4.2)</td><td>2 (1.2)</td><td>5 (3.0)</td><td>0</td><td>1 (0.6)</td><td>1 (0.6)</td><td>2 (1.2)</td><td>3 (1.8)</td></tr><tr><td>Dizziness</td><td>6 (3.6)</td><td>4 (2.4)</td><td>2 (1.2)</td><td>0</td><td>0</td><td>3 (1.8)</td><td>1 (0.6)</td><td>2 (1.2)</td></tr><tr><td>Paresthesia</td><td>4 (2.4)</td><td>3 (1.8)</td><td>1 (0.6)</td><td>0</td><td>1 (0.6)</td><td>1 (0.6)</td><td>1 (0.6)</td><td>1 (0.6)</td></tr><tr><td>Vomiting</td><td>4 (2.4)</td><td>2 (1.2)</td><td>2 (1.2)</td><td>0</td><td>2 (1.2)</td><td>0</td><td>2 (1.2)</td><td>0</td></tr><tr><td>Diarrhea</td><td>4 (2.4)</td><td>3 (1.8)</td><td>1 (0.6)</td><td>0</td><td>3 (1.8)</td><td>0</td><td>1 (0.6)</td><td>0</td></tr><tr><td>Gastroenteritis viral</td><td>6 (3.6)</td><td>3 (1.8)</td><td>3 (1.8)</td><td>0</td><td>6 (3.6)</td><td>0</td><td>0</td><td>0</td></tr><tr><td>Influenza</td><td>4 (2.4)</td><td>1 (0.6)</td><td>3 (1.8)</td><td>0</td><td>4 (2.4)</td><td>0</td><td>0</td><td>0</td></tr><tr><td>Nasopharyngitis</td><td>12 (7.2)</td><td>10 (6.0)</td><td>2 (1.2)</td><td>0</td><td>12 (7.2)</td><td>0</td><td>0</td><td>0</td></tr><tr><td>Sinusitis</td><td>11 (6.6)</td><td>4 (2.4)</td><td>6 (3.6)</td><td>1 (0.6)</td><td>10 (6.0)</td><td>1 (0.6)</td><td>0</td><td>0</td></tr><tr><td>Upper respiratory tract infection</td><td>18 (10.8)</td><td>15 (9.0)</td><td>3 (1.8)</td><td>0</td><td>18 (10.8)</td><td>0</td><td>0</td><td>0</td></tr><tr><td>Urinary tract infection</td><td>5 (3.0)</td><td>3 (1.8)</td><td>2 (1.2)</td><td>0</td><td>5 (3.0)</td><td>0</td><td>0</td><td>0</td></tr></table> |
41f9e87ccec817f04562014e21866970569d211e8baf23b38a50e55b498769ad.png | simple | <table><tr><td>Clinical characteristic</td><td>CCR7+ MUC1+</td><td>CCR7+ MUC1-</td><td>CCR7- MUC1+</td><td>CCR7- MUC1-</td><td><i>P value</i></td></tr><tr><td>Gender</td><td></td><td></td><td></td><td></td><td>0.46</td></tr><tr><td> Male</td><td>57/116</td><td>12/116</td><td>17/116</td><td>30/116</td><td></td></tr><tr><td> Female</td><td>14/37</td><td>5/37</td><td>9/37</td><td>9/37</td><td></td></tr><tr><td>Age(year)</td><td></td><td></td><td></td><td></td><td>0.61</td></tr><tr><td> ≥50</td><td>52/108</td><td>11/108</td><td>20/108</td><td>25/108</td><td></td></tr><tr><td> <50</td><td>19/45</td><td>6/45</td><td>6/45</td><td>14/45</td><td></td></tr><tr><td>Length of tumor(cm)</td><td></td><td></td><td></td><td></td><td>0.65</td></tr><tr><td> <3 cm</td><td>16/35</td><td>4/35</td><td>4/35</td><td>11/35</td><td></td></tr><tr><td> 3 ~ 5 cm</td><td>34/72</td><td>8/72</td><td>16/72</td><td>14/72</td><td></td></tr><tr><td> >5 cm</td><td>21/46</td><td>5/46</td><td>6/46</td><td>14/46</td><td></td></tr><tr><td>Invasion depth</td><td></td><td></td><td></td><td></td><td>0.170</td></tr><tr><td> T1</td><td>9/25</td><td>2/25</td><td>2/25</td><td>12/25</td><td></td></tr><tr><td> T2</td><td>35/76</td><td>9/76</td><td>14/76</td><td>18/76</td><td></td></tr><tr><td> T3 + T4a</td><td>27/52</td><td>6/52</td><td>10/52</td><td>9/52</td><td></td></tr><tr><td>Lymphatic metastasis</td><td></td><td></td><td></td><td></td><td><0.001</td></tr><tr><td> Yes</td><td>53/89</td><td>7/89</td><td>18/89</td><td>11/89</td><td></td></tr><tr><td> No</td><td>18/64</td><td>10/64</td><td>8/64</td><td>28/64</td><td></td></tr><tr><td>Differentiation</td><td></td><td></td><td></td><td></td><td>0.06</td></tr><tr><td> Well/moderate</td><td>26/67</td><td>8/67</td><td>9/67</td><td>24/67</td><td></td></tr><tr><td> Low</td><td>45/86</td><td>9/86</td><td>17/86</td><td>15/86</td><td></td></tr><tr><td> Weight loss</td><td></td><td></td><td></td><td></td><td>0.2</td></tr><tr><td> Yes</td><td>12/23</td><td>3/23</td><td>6/23</td><td>2/23</td><td></td></tr><tr><td> No</td><td>59/130</td><td>14/130</td><td>20/130</td><td>37/130</td><td></td></tr><tr><td>Regional lymphatic recurrence</td><td></td><td></td><td></td><td></td><td><0.001</td></tr><tr><td> Yes</td><td>46/78</td><td>8/78</td><td>15/78</td><td>9/78</td><td></td></tr><tr><td> No</td><td>25/75</td><td>9/75</td><td>11/75</td><td>30/75</td><td></td></tr></table> |
b31fc130dda439a6daf5515dfc30360729a045eea46d138f4f89939e0fbb893d.png | simple | <table><tr><td>Panel</td><td>Criteria</td></tr><tr><td>Professional</td><td>• Be 18 years or older, AND• Live in Australia, Canada, Ireland, New Zealand, United Kingdom or the United States, AND• Have a minimum of 2 years’ experience specialising in research on or treatment of problem gambling.</td></tr><tr><td>Lived experience</td><td>• Be 18 years or older, AND• Live in Australia, Canada, Ireland, New Zealand, United Kingdom or the United States, AND• Have a lived experience of gambling problems, but are currently recovered and have experience in an advocacy or peer support role, OR• Are a family member or friend who has assisted a person with a gambling problem and have experience in an advocacy or peer support role.</td></tr></table> |
eb67b26ce5be81dd22eeb1fbc8959d925ad217c1eda35ddae7c99323e5e20751.png | complex | <table><tr><td colspan="5">Case study</td></tr><tr><td> </td><td colspan="2">DHp: 9 contacts out of 46</td><td colspan="2">RR: 24 contacts out of 68</td></tr><tr><td> </td><td>Contacts among top 9</td><td>p-value</td><td>Contacts among top 24</td><td>p-value</td></tr><tr><td>MI</td><td>3</td><td>0.2503</td><td>9</td><td>0.4864929</td></tr><tr><td>MIc</td><td>4</td><td>0.0800</td><td>9</td><td>0.4864929</td></tr></table> |
3a327857ec4455cdb85208db84be2f77ff465656262f9b732b86525e33ee23e1.png | simple | <table><tr><td></td><td>Control</td><td><i>E. coli</i></td><td><i>p</i> value</td><td>Control</td><td><i>S.</i> Typhimurium</td><td><i>p</i> value</td></tr><tr><td>Apical IL-8 concentration</td><td>101.92 ± 4.54</td><td>425.60 ± 20.12</td><td>0.0015</td><td>143.72 ± 16.98</td><td>1129.74 ± 50.37</td><td><0.001</td></tr><tr><td>Basolateral IL-8 concentration</td><td>16.68 ± 2.78</td><td>1188.47 ± 45.02</td><td><0.001</td><td>48.14 ± 14.43</td><td>2516.64 ± 66.17</td><td><0.001</td></tr></table> |
72ed6bf244205fe06c04f9ef4546d502cecf382b5299bb600776111432f042c5.png | complex | <table><tr><td>Evaluation</td><td colspan="5">Days after Enrolment</td></tr><tr><td></td><td>0</td><td>3–4</td><td>13–15</td><td>24–32</td><td>84–92</td></tr><tr><td>Notification to study center</td><td>X</td><td></td><td></td><td></td><td></td></tr><tr><td>Entry criteria</td><td>X</td><td></td><td></td><td></td><td></td></tr><tr><td>Written Informed Consent</td><td>X*</td><td>X*</td><td></td><td></td><td></td></tr><tr><td>Demography</td><td>X</td><td></td><td></td><td></td><td></td></tr><tr><td>Clinical data</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td></tr><tr><td>(Serious) Adverse events</td><td>X</td><td>X</td><td>X</td><td>X</td><td>X</td></tr><tr><td>Mortality</td><td></td><td>X</td><td>X</td><td>X</td><td>X</td></tr><tr><td>Blood culture</td><td>X</td><td></td><td></td><td></td><td></td></tr><tr><td>Urine culture</td><td>X</td><td></td><td></td><td>X</td><td></td></tr><tr><td>Randomization and allocation to study treatment</td><td></td><td>X</td><td></td><td></td><td></td></tr><tr><td>End of treatment assessment</td><td></td><td></td><td>X</td><td></td><td></td></tr><tr><td>Contact – in person</td><td>X</td><td>X</td><td></td><td>X</td><td></td></tr><tr><td>Contact – by phone</td><td></td><td></td><td>X</td><td></td><td>X</td></tr></table> |
998a7ab8de33fcac39b21ce38502f9b17a10cb278cdfd09bd77d7756851afaa6.png | simple | <table><tr><td>Patient number</td><td>Sex</td><td>Age at diagnosis (years)</td><td>Follow up (years)</td><td>Surfactant disorder</td><td>Mutation</td></tr><tr><td>1*</td><td>M</td><td>0.3</td><td>2.9</td><td>SP-C</td><td>c.424delC</td></tr><tr><td>2*</td><td>M</td><td>0.4</td><td>3.6</td><td>SP-C</td><td>c.566 G > A (C189Y)</td></tr><tr><td>3*</td><td>F</td><td>0.3</td><td>3.8</td><td>SP-C</td><td>c.566 G > A (C189Y)</td></tr><tr><td>4*</td><td>M</td><td>0.2</td><td>1.4</td><td>SP-C</td><td>c.325-1 G > A</td></tr><tr><td>5*</td><td>M</td><td>2.4</td><td>0.4</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>6*</td><td>F</td><td>5.8</td><td>0</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>7*</td><td>F</td><td>1.6</td><td>2.4</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>8*</td><td>F</td><td>0.4</td><td>1.4</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>9*</td><td>F</td><td>1.2</td><td>1.2</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>10*</td><td>M</td><td>0.8</td><td>2.5</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>11*</td><td>F</td><td>0.3</td><td>4.2</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>12*</td><td>F</td><td>0</td><td>1.8</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>13*</td><td>M</td><td>1.6</td><td>md</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>14*</td><td>M</td><td>0.7</td><td>4.2</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>15*</td><td>M</td><td>2.2</td><td>3.1</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>16*</td><td>F</td><td>0.2</td><td>6.2</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>17*</td><td>F</td><td>2.7</td><td>11.7</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>18*</td><td>F</td><td>0.5</td><td>12.4</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>19*</td><td>M</td><td>0.4</td><td>6.6</td><td>SP-C</td><td>c.218 T > C (I73T)</td></tr><tr><td>20*</td><td>M</td><td>0.3</td><td>2.4</td><td>SP-C</td><td>c.581 T > C (L194P)</td></tr><tr><td>21*</td><td>M</td><td>8.5</td><td>0</td><td>SP-C</td><td>c.563 T > C (L188P)</td></tr><tr><td>22*</td><td>F</td><td>0.4</td><td>17.2</td><td>SP-C</td><td>c.116 T > C (V39A)</td></tr><tr><td>23</td><td>M</td><td>0</td><td>0.1</td><td>SP-B</td><td>g.1549 C > GAA (121ins2) −/−</td></tr><tr><td>24</td><td>M</td><td>0</td><td>0.1</td><td>SP-B</td><td>g.1549 C > GAA (121ins2) −/−</td></tr><tr><td>25</td><td>M</td><td>0.2</td><td>0</td><td>SP-B</td><td>g.1549 C > GAA (121ins2) −/−</td></tr><tr><td>26</td><td>F</td><td>0</td><td>0.2</td><td>SP-B</td><td>g.1549 C > GAA (121ins2) −/−</td></tr><tr><td>27</td><td>M</td><td>0.1</td><td>0</td><td>SP-B</td><td>c.496delG −/−</td></tr><tr><td>28</td><td>M</td><td>0</td><td>0.1</td><td>SP-B</td><td>Y253X −/−</td></tr><tr><td>29</td><td>F</td><td>0</td><td>0.2</td><td>SP-B</td><td>672 + 2del5 −/−</td></tr><tr><td>30*</td><td>F</td><td>0</td><td>9.2</td><td>ABCA3</td><td>c.3518 C > G (T1173R) −/−</td></tr><tr><td>31*</td><td>M</td><td>0.3</td><td>10.9</td><td>ABCA3</td><td>c.757 G > C (D253H) −/−</td></tr><tr><td>32*</td><td>F</td><td>2.3</td><td>MD</td><td>ABCA3</td><td>c.3518 C > G (T1173R) −/−</td></tr><tr><td>33*</td><td>M</td><td>0.3</td><td>3.4</td><td>ABCA3</td><td>P585 −/−</td></tr><tr><td>34*</td><td>F</td><td>12.3</td><td>3</td><td>ABCA3</td><td>c.3518 C > G (T1173R) −/−</td></tr><tr><td>35*</td><td>F</td><td>0.1</td><td>4.8</td><td>TTF1</td><td>c.786_787del2 (p.L263fs)</td></tr><tr><td>36*</td><td>F</td><td>0.1</td><td>1.5</td><td>TTF1</td><td>c.493 C > T(R165W)</td></tr><tr><td> </td><td>Sex ratio 1</td><td>Median 0.3</td><td>Median 2.4</td><td> </td><td> </td></tr></table> |
5c4d6bc6f8e3952699e060921f662dd1dd16c1e074f8b7d26acfc47b32c26454.png | complex | <table><tr><td>Molecular function</td><td>GO Name</td><td>Count</td><td>%</td><td><i>P </i>value</td><td>FDR</td></tr><tr><td>GO:0004984</td><td>olfactory receptor activity</td><td>178</td><td>32.07207</td><td>5.862E-158</td><td>8.27E-155</td></tr><tr><td>GO:0034212</td><td>peptide N-acetyltransferase activity</td><td>3</td><td>0.540541</td><td>0.006224705</td><td>8.432901467</td></tr><tr><td>GO:0004596</td><td>peptide alpha-N-acetyltransferase activity</td><td>3</td><td>0.540541</td><td>0.006224705</td><td>8.432901467</td></tr><tr><td>GO:0005344</td><td>oxygen transporter activity</td><td>4</td><td>0.720721</td><td>0.007951513</td><td>10.65236765</td></tr><tr><td>GO:0005218</td><td>intracellular ligand-gated calcium channel activity</td><td>3</td><td>0.540541</td><td>0.01014878</td><td>13.40426119</td></tr><tr><td>GO:0005219</td><td>ryanodine-sensitive calcium-release channel activity</td><td>3</td><td>0.540541</td><td>0.01014878</td><td>13.40426119</td></tr><tr><td>GO:0042043</td><td>neurexin binding</td><td>3</td><td>0.540541</td><td>0.020398884</td><td>25.23210706</td></tr><tr><td>GO:0004683</td><td>calmodulin-dependent protein kinase activity</td><td>4</td><td>0.720721</td><td>0.026734392</td><td>31.7727638</td></tr><tr><td>Biological Process</td><td>GO Name</td><td>Count</td><td>%</td><td><i>P</i> value</td><td>FDR</td></tr><tr><td>GO:0007608</td><td>sensory perception of smell</td><td>179</td><td>32.25225</td><td>1.284E-157</td><td>2.15E-154</td></tr><tr><td>GO:0007606</td><td>sensory perception of chemical stimulus</td><td>179</td><td>32.25225</td><td>6.6567E-148</td><td>1.11E-144</td></tr><tr><td>GO:0007600</td><td>sensory perception</td><td>181</td><td>32.61261</td><td>4.4745E-105</td><td>7.48E-102</td></tr><tr><td>GO:0050890</td><td>cognition</td><td>185</td><td>33.33333</td><td>3.8912E-100</td><td>6.51E-97</td></tr><tr><td>GO:0007186</td><td>G-protein coupled receptor protein signaling pathway</td><td>189</td><td>34.05405</td><td>2.47502E-87</td><td>4.14E-84</td></tr><tr><td>GO:0050877</td><td>neurological system process</td><td>193</td><td>34.77477</td><td>3.0364E-85</td><td>5.08E-82</td></tr><tr><td>GO:0007166</td><td>cell surface receptor linked signal transduction</td><td>201</td><td>36.21622</td><td>5.69264E-59</td><td>9.52E-56</td></tr><tr><td>GO:0051258</td><td>protein polymerization</td><td>9</td><td>1.621622</td><td>0.000194423</td><td>0.324648125</td></tr><tr><td>GO:0007018</td><td>microtubule-based movement</td><td>11</td><td>1.981982</td><td>0.00446377</td><td>7.208705512</td></tr><tr><td>GO:0015671</td><td>oxygen transport</td><td>4</td><td>0.720721</td><td>0.008202995</td><td>12.8682872</td></tr><tr><td>GO:0051225</td><td>spindle assembly</td><td>4</td><td>0.720721</td><td>0.017671563</td><td>25.78281061</td></tr><tr><td>GO:0015669</td><td>gas transport</td><td>4</td><td>0.720721</td><td>0.020691633</td><td>29.50783311</td></tr><tr><td>GO:0007158</td><td>neuron adhesion</td><td>3</td><td>0.540541</td><td>0.020837821</td><td>29.68360693</td></tr><tr><td>GO:0035176</td><td>social behavior</td><td>4</td><td>0.720721</td><td>0.023976546</td><td>33.35959701</td></tr><tr><td>GO:0044065</td><td>regulation of respiratory system process</td><td>3</td><td>0.540541</td><td>0.034182249</td><td>44.10238982</td></tr><tr><td>GO:0002087</td><td>regulation of respiratory gaseous exchange by neurological system process</td><td>3</td><td>0.540541</td><td>0.034182249</td><td>44.10238982</td></tr><tr><td>GO:0007625</td><td>grooming behavior</td><td>3</td><td>0.540541</td><td>0.049984805</td><td>57.57958749</td></tr><tr><td>Cellular Component</td><td>GO Name</td><td>Count</td><td>%</td><td><i>P</i> value</td><td>FDR</td></tr><tr><td>GO:0005886</td><td>plasma membrane</td><td>241</td><td>43.42342</td><td>5.86933E-35</td><td>7.69E-32</td></tr><tr><td>GO:0016021</td><td>integral to membrane</td><td>289</td><td>52.07207</td><td>1.23979E-32</td><td>1.62E-29</td></tr><tr><td>GO:0031224</td><td>intrinsic to membrane</td><td>293</td><td>52.79279</td><td>1.36024E-31</td><td>1.78E-28</td></tr><tr><td>GO:0005833</td><td>hemoglobin complex</td><td>4</td><td>0.720721</td><td>0.005887046</td><td>7.444488585</td></tr><tr><td>Pathway</td><td>Pathway name</td><td>Count</td><td>%</td><td><i>P</i> value</td><td>FDR</td></tr><tr><td>hsa04740</td><td>Olfactory transduction</td><td>170</td><td>30.63063</td><td>2.80E-137</td><td>3.05E-134</td></tr><tr><td>hsa05130</td><td>Pathogenic Escherichia coli infection</td><td>8</td><td>1.441441</td><td>0.027376</td><td>25.8675045</td></tr><tr><td>OMIM_DISEASE</td><td> </td><td>Count</td><td>%</td><td><i>P</i> value</td><td>FDR</td></tr><tr><td colspan="2">Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study</td><td>3</td><td>0.540541</td><td>0.011938</td><td>12.52341992</td></tr><tr><td colspan="2">Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study</td><td>3</td><td>0.540541</td><td>0.026364</td><td>25.7439374</td></tr><tr><td colspan="2">C1r/C1s deficiency, combined</td><td>2</td><td>0.36036</td><td>0.034033</td><td>32.00636058</td></tr></table> |
293ae19581b00202bd44735fb0fea81918720fec8fe9134c803b471a5cb3b34f.png | simple | <table><tr><td></td><td>Mean+/-SD(nmol/L)</td><td><i>P</i>value</td><td>< 25 nmol/L,% (95%CI)</td><td>< 50 nmol/L,% (95%CI)</td><td>< 75 nmol/L,% (95%CI)</td></tr><tr><td>0-1y stage (infancy)</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Total (n = 2116)</td><td>98.7 ± 47.1</td><td></td><td>0.4 (NC)</td><td>5.4 (4.4-6.4)</td><td>33.6 (31.6-35.6)</td></tr><tr><td>Gender</td><td></td><td>0.763</td><td></td><td></td><td></td></tr><tr><td>Male (n = 1221)</td><td>98.5 ± 47.0</td><td></td><td>0.4 (NC)</td><td>5.3 (4.0-6.6)</td><td>34.3 (31.6-37.0)</td></tr><tr><td>Female (n = 895)</td><td>99.1 ± 47.2</td><td></td><td>0.3 (NC)</td><td>5.5 (4.0-7.0)</td><td>32.7 (29.6-35.8)</td></tr><tr><td>2-5y stage (preschool)</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Total (n = 2269)</td><td>69.6 ± 30.4</td><td></td><td>1.1 (NC)</td><td>21.9 (20.2-23.6)</td><td>68.6 (66.7-70.5)</td></tr><tr><td>Gender</td><td></td><td>0.108</td><td></td><td></td><td></td></tr><tr><td>Male (n = 1454)</td><td>70.4 ± 31.4</td><td></td><td>1.2 (NC)</td><td>20.8 (18.7-22.9)</td><td>67.7 (65.3-70.1)</td></tr><tr><td>Female (n = 815)</td><td>68.2 ± 28.6</td><td></td><td>1.1 (NC)</td><td>24.0 (21-27)</td><td>70.1 (67.0-73.2)</td></tr><tr><td>6-11y stage (school age)</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Total (n = 1440)</td><td>56.1 ± 19.9</td><td></td><td>2.0 (NC)</td><td>40.4 (37.9-42.9)</td><td>88.3 (86.6-90.0)</td></tr><tr><td>Gender</td><td></td><td>0.969</td><td></td><td></td><td></td></tr><tr><td>Male (n = 1019)</td><td>56.1 ± 18.7</td><td></td><td>1.6 (NC)</td><td>39.1 (36.1-42.1)</td><td>88.8 (86.9-90.7)</td></tr><tr><td>Female (n = 421)</td><td>56.1 ± 22.6</td><td></td><td>3.1 (NC)</td><td>43.7 (39.0-48.4)</td><td>86.9 (83.7-90.1)</td></tr><tr><td>12-16y stage(adolescence)</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Total (n = 183)</td><td>52.1 ± 17.0</td><td></td><td>3.3 (NC)</td><td>46.4 (39.2-53.6)</td><td>89.6 (85.2-94.0)</td></tr><tr><td>Gender</td><td></td><td>0.051</td><td></td><td></td><td></td></tr><tr><td>Male (n = 135)</td><td>53.5 ± 17.0</td><td></td><td>2.2 (NC)</td><td>44.4 (36-52.8)</td><td>88.1 (82.6-93.6)</td></tr><tr><td>Female (n = 48)</td><td>48.0 ± 16.6</td><td></td><td>6.3 (NC)</td><td>52.1 (38-66.2)</td><td>93.8 (87.6-100)</td></tr></table> |
777505c5740f8bd50f3c432922e31fd3504c060f8d05d486fb482dddd58de9e0.png | complex | <table><tr><td>Follow up point</td><td>Variables in the equation</td><td>OR (95% CI)</td><td>Nagelkerke<sup>*</sup></td><td>sn/sp</td></tr><tr><td rowspan="2">14 days (n = 235)</td><td>Pain for >30 days in year</td><td>3.2 (1.9 to 5.6)</td><td>0.26</td><td>90/25</td></tr><tr><td>Pain (for every 1 point increase)</td><td>0.8 (0.8 to 0.9)</td><td> </td><td> </td></tr><tr><td rowspan="4">30 days (n = 131)</td><td>Duration</td><td> </td><td>0.32</td><td>92/29</td></tr><tr><td>< 1 month</td><td>1.0</td><td> </td><td> </td></tr><tr><td>1–3 months</td><td>5.6 (1.8 to 17.0)</td><td> </td><td> </td></tr><tr><td>>3 months</td><td>2.4(1.1 to 5.5)</td><td> </td><td> </td></tr><tr><td rowspan="4">90 days (n = 150)</td><td> </td><td> </td><td>0.45</td><td>94/23</td></tr><tr><td>Duration</td><td> </td><td> </td><td> </td></tr><tr><td>< 1 month</td><td>1.0</td><td> </td><td> </td></tr><tr><td>1–3 months</td><td>9.3 (3.0 to 29.0)</td><td> </td><td> </td></tr><tr><td> </td><td>>3 months</td><td>3.0(1.3 to 7.0)</td><td> </td><td> </td></tr></table> |
c0aae4fc09d1214ac974d304eeda73b54bd0bb518bd0b048644c723311aa3280.png | complex | <table><tr><td>Chemistry</td><td>Selection</td><td>Counter-selection</td><td>Targeted or identified targets</td><td>Number of cycles</td><td>Reference</td></tr><tr><td colspan="6"><i>Mammalian Cells</i></td></tr><tr><td>DNA</td><td>YPEN-1</td><td>N9</td><td>Pigpen</td><td>8</td><td>[58]</td></tr><tr><td>DNA</td><td>B lymphoma cells</td><td>No</td><td>ND</td><td>10</td><td>[71]</td></tr><tr><td>DNA</td><td>Differenciated PC12</td><td>PC12</td><td>ND</td><td>6</td><td>[60]</td></tr><tr><td>DNA</td><td>U251</td><td>No</td><td>Tenascin-C</td><td>21</td><td>[67]</td></tr><tr><td>2′F-Py RNA</td><td>CHO-kinin B1 receptor</td><td>No</td><td>Kinin B1 receptor</td><td>8</td><td>[72]</td></tr><tr><td>2′F-Py RNA</td><td>PC12-MEN2A</td><td>PC12/PC12-MEN2A</td><td>RET</td><td>15</td><td>[16]</td></tr><tr><td>2′F-Py RNA</td><td>CHO-TbRIII</td><td>CHO</td><td>TbRIII</td><td>11</td><td>[73]</td></tr><tr><td>DNA</td><td>aMSCs</td><td>No</td><td>ND</td><td>11</td><td>[74]</td></tr><tr><td>DNA</td><td>CCRF-CEM</td><td>Ramos</td><td>PTK7</td><td>20</td><td>[65,70]</td></tr><tr><td>DNA</td><td>Ramos</td><td>No</td><td>mmunoglobin heavy mu chain</td><td>23</td><td>[69,75]</td></tr><tr><td>DNA</td><td>SAOS-2 osteoblasts</td><td>No</td><td>ND</td><td>10</td><td>[68]</td></tr><tr><td>DNA</td><td>MEAR</td><td>BNL</td><td>Non-muscle myosin</td><td>16</td><td>[62]</td></tr><tr><td>DNA</td><td>NCI-H69</td><td>NCI-H661</td><td>ND</td><td>25</td><td>[76]</td></tr><tr><td>DNA</td><td>EPCs</td><td>No</td><td>ND</td><td>10</td><td>[77]</td></tr><tr><td>DNA</td><td>iDC (mDC)</td><td>mDC (iDC)</td><td>Several (see reference)</td><td>10</td><td>[66]</td></tr><tr><td>DNA</td><td>Burkitt lymphoma cells</td><td>No</td><td>ND</td><td>10</td><td>[59]</td></tr><tr><td>DNA</td><td>A549</td><td>HLAMP</td><td>ND</td><td>25</td><td>[78]</td></tr><tr><td>DNA</td><td>HL60</td><td>NB4</td><td>ND</td><td>16</td><td>[64]</td></tr><tr><td>2′F-Py RNA</td><td>U87MG</td><td>T98G</td><td>ND</td><td>14</td><td>[79]</td></tr><tr><td>DNA</td><td>CT26-E2</td><td>CT26</td><td>Virus Glycoprotein E2</td><td>13</td><td>[80]</td></tr><tr><td>DNA</td><td>Infected A549</td><td>Non-infected A549</td><td>ND</td><td>13</td><td>[63]</td></tr><tr><td>RNA</td><td>SKBR3</td><td>SKBR3/siHER-2/MDAMB231</td><td>HER-2</td><td>20</td><td>[81]</td></tr><tr><td>DNA</td><td>HEK293T-TLR2-Fc</td><td>No</td><td>TLR2</td><td>7</td><td>[82]</td></tr><tr><td>DNA</td><td>Vaccinia virus-infected HeLa</td><td>Non-infected HeLa</td><td>Hemagglutinin</td><td>20</td><td>[61]</td></tr><tr><td>2′F-Py RNA</td><td>HET-SR-1</td><td>HET-SR</td><td>ND</td><td>10</td><td>[83]</td></tr><tr><td>DNA</td><td>Tov-21G/CAOV-3</td><td>HeLa</td><td>ND</td><td>22</td><td>[84]</td></tr><tr><td>DNA</td><td>DLD-1/HCT 116</td><td>HCT 116/HT-29</td><td>ND</td><td>16</td><td>[85]</td></tr><tr><td>DNA</td><td>NIH3T3</td><td>IL-17RA-deficient NIH3T3</td><td>IL-17RA</td><td>12</td><td>[86]</td></tr><tr><td colspan="6"><i>Viruses</i></td></tr><tr><td>2′NH2-Py RNA</td><td>Human cytomegalovirus</td><td>No</td><td>Glycoprotein B and H</td><td>16</td><td>[57]</td></tr><tr><td>RNA</td><td>Influenza A panama virus</td><td>Influenza A Aichi Virus</td><td>Haemagglutinin</td><td>10</td><td>[87]</td></tr><tr><td colspan="6"><i>Bacteria</i></td></tr><tr><td>DNA</td><td><i>B. anthracis</i> spores</td><td>No</td><td>ND</td><td>4</td><td>[55]</td></tr><tr><td>DNA</td><td><i>M. Tuberculosis</i> H37Rv</td><td><i>M. Tuberculosis</i> BCG</td><td>ND</td><td>10</td><td>[88]</td></tr><tr><td>DNA</td><td><i>L. Acidophilus</i></td><td>No</td><td>S-layer protein</td><td>8</td><td>[89]</td></tr><tr><td>DNA</td><td><i>S. aureus</i></td><td><i>Streptococcus/S. epidermidis</i></td><td>ND</td><td>5</td><td>[90]</td></tr><tr><td>DNA</td><td><i>C. Jejuni</i></td><td>Non relevant mix</td><td>ND</td><td>10</td><td>[91]</td></tr><tr><td>DNA</td><td><i>P. aeruginosa</i></td><td><i>S. Maltophilia/A. Baumannii</i></td><td>ND</td><td>16</td><td>[92]</td></tr><tr><td colspan="6"><i>Parasites</i></td></tr><tr><td>RNA</td><td><i>T. brucei</i></td><td>No</td><td>ND</td><td>12</td><td>[56]</td></tr><tr><td>2′F-Py RNA</td><td><i>T. cruzi</i> trypomastigote</td><td>Epimastigote</td><td>Several (see reference)</td><td>8</td><td>[93]</td></tr><tr><td>2′NH2-Py RNA</td><td><i>T. brucei</i></td><td>No</td><td>ND</td><td>13</td><td>[94]</td></tr></table> |
5e59ad9104ccdccb787406e45736b41bc8cd7bbc99dfa083923953adc16e63bd.png | complex | <table><tr><td rowspan="2">PRN</td><td colspan="2">PM</td><td colspan="2">MPDR</td></tr><tr><td>Mean (mm)</td><td>Standard Deviation (mm)</td><td>Mean (mm)</td><td>Standard Deviation (mm)</td></tr><tr><td>PRN 3</td><td>10.9</td><td>0.4</td><td>0.01</td><td>0.4</td></tr><tr><td>PRN 6</td><td>3.4</td><td>0.3</td><td>−0.01</td><td>0.4</td></tr><tr><td>PRN 10</td><td>29.6</td><td>1.5</td><td>0.07</td><td>0.7</td></tr><tr><td>PRN 16</td><td>4.8</td><td>0.4</td><td>0.05</td><td>0.6</td></tr><tr><td>PRN 18</td><td>7.5</td><td>0.3</td><td>−0.01</td><td>0.5</td></tr><tr><td>PRN 21</td><td>1.5</td><td>0.2</td><td>−0.05</td><td>0.5</td></tr><tr><td>PRN 24</td><td>−16.0</td><td>0.3</td><td>0.01</td><td>0.5</td></tr><tr><td>PRN 25</td><td>23.1</td><td>0.5</td><td>−0.03</td><td>0.5</td></tr><tr><td>PRN 29</td><td>−6.7</td><td>0.4</td><td>0.03</td><td>0.5</td></tr></table> |
39b53a535f6856914279a7212ef15faf51efad8fe98f62e9d7796ebe2e164099.png | simple | <table><tr><td>Venue</td><td>Cluster 1 (<i>N</i> = 2715) low-use mean</td><td>Cluster 2 (<i>N</i> = 1236) high-use mean</td><td>Importance (%)</td></tr><tr><td>Sports centre</td><td>1.20</td><td>2.69</td><td>1.00</td></tr><tr><td>Cinema or theatre</td><td>1.35</td><td>2.73</td><td>1.00</td></tr><tr><td>Vending machine</td><td>1.19</td><td>2.62</td><td>1.00</td></tr><tr><td>Street stall or small shop</td><td>1.70</td><td>2.9</td><td>1.00</td></tr><tr><td>Newsagent</td><td>1.13</td><td>2.68</td><td>1.00</td></tr><tr><td>Petrol station</td><td>1.23</td><td>2.64</td><td>1.00</td></tr><tr><td>Cafe</td><td>1.81</td><td>2.94</td><td>1.00</td></tr><tr><td>A fast food restaurant (KFC, McDonalds)</td><td>1.76</td><td>2.83</td><td>0.99</td></tr><tr><td>A convenience store (7-eleven)</td><td>1.84</td><td>2.99</td><td>0.94</td></tr></table> |
32a8d1a17fd739eff99ba58d21dad99e12ccc9137b85d67c19297fa0ea95de56.png | simple | <table><tr><td></td><td>Group A (<i>n</i> = 31) (Peg-IFNα + RBV + placebo)</td><td>Group B (<i>n</i> = 31) (Peg-IFNα + RBV + Silybin, Vit E, phospholipids)</td><td><i>P</i> Value</td></tr><tr><td>Psychological disorders</td><td>14%</td><td>12%</td><td>NS</td></tr><tr><td>Hypercholesterolemia</td><td>16%</td><td>32%</td><td><i>P</i> < 0.01</td></tr><tr><td>Fatigue</td><td>48%</td><td>44%</td><td>NS</td></tr><tr><td>Headache</td><td>41%</td><td>42%</td><td>NS</td></tr><tr><td>Musculoskeletal pain</td><td>54%</td><td>35%</td><td><i>P</i> < 0.01</td></tr><tr><td>Myalgia</td><td>58%</td><td>32%</td><td><i>P</i> < 0.01</td></tr><tr><td>Hypertriglyceridemia</td><td>44%</td><td>30%</td><td><i>P</i> < 0.01</td></tr><tr><td>Nausea</td><td>31%</td><td>24%</td><td><i>P</i> < 0.05</td></tr><tr><td>Anorexia</td><td>6%</td><td>8%</td><td>NS</td></tr><tr><td>Irritability</td><td>30%</td><td>22%</td><td><i>P</i> < 0.05</td></tr><tr><td>Hyperglycemia</td><td>13%</td><td>8%</td><td><i>P</i> < 0.05</td></tr><tr><td>Weight loss</td><td>12%</td><td>7%</td><td><i>P</i> < 0.05</td></tr><tr><td>Decrease of hemoglobin values at the end of treatment</td><td>from 13.6 g/dL (range 11.4–14.4) to 11.6 g/dL (range 10.4–14.2 g/dL)</td><td>from 13.6 g/dL (range 11.6–15.9 g/dL) to 10.6 (range 10.4–12.8 g/dL)</td><td>NS</td></tr></table> |
6237d670249a78db45574ea4ba922bfa2b074da3e65c8cb919269be4ef42304d.png | complex | <table><tr><td>MIGS ID</td><td>Property</td><td>Term</td><td>Evidence code</td></tr><tr><td rowspan="8"></td><td rowspan="8">Current classification</td><td>Domain <i>Bacteria</i></td><td>TAS [15]</td></tr><tr><td>Phylum <i>Proteobacteria</i></td><td>TAS [16]</td></tr><tr><td>Class <i>Betaproteobacteria</i></td><td>TAS [17,18]</td></tr><tr><td>Order <i>Burkholderiales</i></td><td>TAS [18,19]</td></tr><tr><td>Family <i>Burkholderiaceae</i></td><td>TAS [18,20]</td></tr><tr><td>Genus <i>Burkholderia</i></td><td>TAS [21-23]</td></tr><tr><td>Species <i>Burkholderia sp.</i></td><td>IDA</td></tr><tr><td>Strain WSM2230</td><td>IDA</td></tr><tr><td></td><td>Gram stain</td><td>Negative</td><td>IDA</td></tr><tr><td></td><td>Cell shape</td><td>Rod</td><td>IDA</td></tr><tr><td></td><td>Motility</td><td>Motile</td><td>IDA</td></tr><tr><td></td><td>Sporulation</td><td>Non-sporulating</td><td>NAS</td></tr><tr><td></td><td>Temperature range</td><td>Mesophile</td><td>IDA</td></tr><tr><td></td><td>Optimum temperature</td><td>30°C</td><td>IDA</td></tr><tr><td></td><td>Salinity</td><td>Non-halophile</td><td>IDA</td></tr><tr><td>MIGS-22</td><td>Oxygen requirement</td><td>Aerobic</td><td>IDA</td></tr><tr><td></td><td>Carbon source</td><td>Varied</td><td>IDA</td></tr><tr><td></td><td>Energy source</td><td>Chemoorganotroph</td><td>NAS</td></tr><tr><td>MIGS-6</td><td>Habitat</td><td>Soil, root nodule, on host</td><td>IDA</td></tr><tr><td>MIGS-15</td><td>Biotic relationship</td><td>Free living, symbiotic</td><td>IDA</td></tr><tr><td>MIGS-14</td><td>Pathogenicity</td><td>Non-pathogenic</td><td>IDA</td></tr><tr><td></td><td>Biosafety level</td><td>1</td><td>IDA</td></tr><tr><td></td><td>Isolation</td><td>Root nodule of <i>Kennedia coccinea</i></td><td>IDA</td></tr><tr><td>MIGS-4</td><td>Geographic location</td><td>Karijini National Park, Australia</td><td>IDA</td></tr><tr><td>MIGS-5</td><td>Soil collection date</td><td>September 2001</td><td>IDA</td></tr><tr><td>MIGS-4.1MIGS-4.2</td><td>LatitudeLongitude</td><td>117.99-22.5</td><td>IDAIDA</td></tr><tr><td>MIGS-4.3</td><td>Depth</td><td>0-10 cm</td><td>IDA</td></tr><tr><td>MIGS-4.4</td><td>Altitude</td><td>Not reported</td><td></td></tr></table> |
5828d99561a0db0cf25edff3fb09cb8b3505c8bd455e7e404de4e20a00077ad8.png | simple | <table><tr><td></td><td>HIV+ group only</td><td></td></tr><tr><td>Median Nadir CD4-T+ cells/μL</td><td>198</td><td>IQR: 31-279</td></tr><tr><td>Median current CD4-T+ cells/μL</td><td>597</td><td>IQR: 342-748</td></tr><tr><td>% Plasma undetectable HIV RNA (<50 cp/mL)<sup>1</sup></td><td>95.5%</td><td>-</td></tr><tr><td>% CSF Undetectable HIV RNA (<50 cp/mL)<sup>2</sup></td><td>97.6%</td><td>-</td></tr><tr><td>Median HIV duration (years)</td><td>20.5</td><td>IQR: 14-25</td></tr><tr><td>% AIDS status (CDC 1993)</td><td>70.5%</td><td>-</td></tr><tr><td>% With past AIDS defining illness</td><td>53%</td><td>-</td></tr><tr><td>Median current cART duration (months)</td><td>30</td><td>IQR: 12-54</td></tr><tr><td>% MSM as HIV risk factor</td><td>89%</td><td>-</td></tr><tr><td>Average educational level (years)</td><td>13.82</td><td>SD: 2.95</td></tr><tr><td>% Current hAND</td><td>61.3%</td><td>-</td></tr><tr><td>% Past hAND</td><td>31.8%</td><td>-</td></tr><tr><td>% APOE any ε4 allele carriers</td><td>30.9% (N = 13)</td><td>-</td></tr><tr><td>% APOE ε4/ε4 allele carriers</td><td>7.1% (N = 3)</td><td>-</td></tr><tr><td>% APOE ε2/ε3 allele carriers</td><td>7.1% (N = 3)</td><td>-</td></tr><tr><td>% APOE ε3/ε3 allele carriers</td><td>61.9% (N = 26)</td><td>-</td></tr></table> |
2f91ec4d5d0ac91d100a578f952488ce852698ad97b70fa84149c653a97b4e83.png | complex | <table><tr><td rowspan="2"> </td><td>Switching</td><td>Combination</td><td>Augmentation</td><td>Total</td></tr><tr><td>(N = 133)</td><td>(N = 80)</td><td>(N = 60)</td><td>(N = 273)</td></tr><tr><td>Age (years), mean (95%CI)</td><td>46.5 (44.5-48.4)</td><td>45.9 (43.4-48.1)</td><td>49.0 (46.5-51.4)</td><td>46.8 (45.5-48.1)</td></tr><tr><td>Sex (female), n (%)</td><td>92 (69.2)</td><td>53 (66.3)</td><td>40 (66.7)</td><td>185 (67.8)</td></tr><tr><td>Marital status, n (%)</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>Single</td><td>16 (12.0)</td><td>11 (13.8)</td><td>14 (23.3)</td><td>41 (15.0)</td></tr><tr><td>Married</td><td>80 (60.2)</td><td>48 (60.0)</td><td>35 (58.3)</td><td>163 (59.7)</td></tr><tr><td>Divorced or separated</td><td>37 (27.8)</td><td>21 (26.3)</td><td>11 (18.3)</td><td>69 (25.3)</td></tr><tr><td>Education level, n (%)</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>No education/ Primary education</td><td>78 (58.7)</td><td>46 (57.5)</td><td>41 (68.3)</td><td>165 (60.4)</td></tr><tr><td>Secondary/ University education</td><td>55 (41.4)</td><td>34 (42.5)</td><td>19 (31.7)</td><td>108 (39.6)</td></tr><tr><td>Family structure, n (%)</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>Living alone</td><td>17 (12.8)</td><td>8 (10.0)</td><td>11 (18.3)</td><td>36 (13.2)</td></tr><tr><td>Couple family</td><td>17 (12.8)</td><td>18 (22.5)</td><td>8 (13.3)</td><td>43 (15.8)</td></tr><tr><td>Parental family</td><td>13 (9.8)</td><td>9 (11.3)</td><td>11 (18.3)</td><td>33 (12.1)</td></tr><tr><td>Own family</td><td>86 (64.7)</td><td>45 (56.3)</td><td>30 (50.0)</td><td>161 (59.0)</td></tr><tr><td>Socioeconomic status, n (%)</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>Low/Low-Middle</td><td>55 (41.4)</td><td>30 (37.5)</td><td>23 (38.3)</td><td>108 (39.6)</td></tr><tr><td>Middle</td><td>62 (46.6)</td><td>40 (50.0)</td><td>31 (51.7)</td><td>133 (48.7)</td></tr><tr><td>Middle-High</td><td>16 (12.0)</td><td>10 (12.5)</td><td>6 (10.0)</td><td>32 (11.7)</td></tr><tr><td>Work status, n (%)</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td>Active</td><td>79 (59.4)</td><td>50 (62.5)</td><td>20 (33.3)</td><td>149 (54.6)</td></tr><tr><td>Unemployed</td><td>39 (29.3)</td><td>19 (23.8)</td><td>20 (33.3)</td><td>78 (28.6)</td></tr><tr><td>Retired/Pensioner</td><td>15 (11.3)</td><td>11 (13.8)</td><td>20 (33.3)</td><td>46 (16.9)</td></tr></table> |
dfee9ff58682a5caacfd8d543b3af2de6cc4778ce8b7257b42d34d066959b1b7.png | simple | <table><tr><td> </td><td>Important or very important to plan for care</td><td>Have discussed wishes for treatment</td><td>Have discussed unacceptable states of health</td><td>Prepared written advance care plan or living will</td></tr><tr><td>Overall</td><td>76.3%</td><td>51.4%</td><td>46.6%</td><td>16.6%</td></tr><tr><td>Sex</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> Male </td><td>69.0%<sup>¶</sup></td><td>47.1%<sup>†</sup></td><td>46.3%</td><td>15.3%</td></tr><tr><td> Female</td><td>82.8%<sup>¶</sup></td><td>55.3%<sup>†</sup></td><td>46.8%</td><td>17.7%</td></tr><tr><td>Age</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> 18–34</td><td>75.9%</td><td> 43.5% </td><td> 40.9% </td><td>8.9%<sup>†</sup></td></tr><tr><td> 35–54</td><td>74.6%</td><td>49.5% </td><td>47.2% </td><td>14.3%<sup>†</sup></td></tr><tr><td> 55–64</td><td>76.6%</td><td>53.8% </td><td>46.8% </td><td>20.5%<sup>†</sup></td></tr><tr><td> ≥65</td><td>81.3%</td><td>69.6% </td><td> 56.3% </td><td>33.0%<sup>†</sup></td></tr><tr><td>Education</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> < or completedHigh school</td><td>69.2%</td><td>48.9%</td><td>41.4%<sup>†</sup></td><td>17.3%</td></tr><tr><td> Some postsecondary</td><td>77.1%</td><td>53.0%</td><td>50.1%<sup>†</sup></td><td>17.3%</td></tr><tr><td> CompletedPostsecondary</td><td>79.2%</td><td>49.2%</td><td>42.5%<sup>†</sup></td><td>15.4%</td></tr><tr><td>Income</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> <$30,000</td><td>75.3%</td><td>53.1%</td><td>44.4%</td><td>18.5%</td></tr><tr><td> $30,000 to $59,999</td><td>74.6%</td><td>54.2%</td><td>47.5%</td><td>16.4%</td></tr><tr><td> $60,000–89,999 </td><td>78.0%</td><td>46.0%</td><td>44.7%</td><td>12.5%</td></tr><tr><td> <$90,000</td><td>75.7%</td><td>51.0%</td><td>47.3%</td><td>17.6%</td></tr><tr><td> Refused</td><td>77.8%</td><td>52.9%</td><td>47.2%</td><td>17.8%</td></tr><tr><td>Residence</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> Large urban</td><td>74.9%</td><td>52.3%</td><td>47.7%</td><td>19.0%</td></tr><tr><td> Other</td><td>77.3%</td><td>50.7%</td><td>45.8%</td><td>14.8%</td></tr><tr><td>Health conditions</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> None</td><td>73.3%</td><td>43.2%<sup>†</sup></td><td>39.2%<sup>¶</sup></td><td>12.2%</td></tr><tr><td> One</td><td>75.3%</td><td>50.2%<sup>†</sup></td><td>44.9%<sup>¶</sup></td><td>18.1%</td></tr><tr><td> Two or more</td><td>80.8%</td><td>62.4%<sup>†</sup></td><td>56.8%<sup>¶</sup></td><td>20.7%</td></tr><tr><td>Involved in funeral planning</td><td> </td><td> </td><td> </td><td> </td></tr><tr><td> Never</td><td>70.2%*</td><td>36.5%<sup>¶</sup></td><td>34.3%<sup>¶</sup></td><td>7.9%<sup>¶</sup></td></tr><tr><td> Once</td><td>80.0%*</td><td>52.5%<sup>¶</sup></td><td>44.0%<sup>¶</sup></td><td>13.5%<sup>¶</sup></td></tr><tr><td> Twice or more</td><td>80.2%*</td><td>67.1%<sup>¶</sup></td><td>61.7%<sup>¶</sup></td><td>28.8%<sup>¶</sup></td></tr></table> |
ce48b4ec2da7e425f3f66791bb4e715cbc414208ad0af6787f4def37198cdd08.png | complex | <table><tr><td></td><td></td><td>ALL</td></tr><tr><td></td><td></td><td>(<i>n</i> = 504)</td></tr><tr><td>Age(years)</td><td>Median(IQR)</td><td>71 (59–80)</td></tr><tr><td></td><td><40 yr</td><td>47 (9.3)</td></tr><tr><td></td><td>≧40 yr. <60 yr</td><td>88 (17.5)</td></tr><tr><td></td><td>≧60 yr. <80 yr</td><td>236 (46.8)</td></tr><tr><td></td><td>≧80 yr</td><td>133 (26.4)</td></tr><tr><td>Male</td><td></td><td>255 (50.6)</td></tr><tr><td rowspan="6">Disease</td><td>Adrenocortical insufficiency</td><td>264 (52.4)</td></tr><tr><td>Adrenal crisis</td><td>194 (38.5)</td></tr><tr><td>Secondary adrenocortical insufficiency</td><td>28 (5.6)</td></tr><tr><td>Post-procedural adrenocortical hypofunction</td><td>10 (2.0)</td></tr><tr><td>Steroid withdrawal syndrome</td><td>5 (1.0)</td></tr><tr><td>Iatrogenic adrenocortical insufficiency</td><td>3 (0.6)</td></tr><tr><td rowspan="4">Department</td><td>Internal medicine</td><td>255 (50.6)</td></tr><tr><td>Neurosurgery</td><td>94 (18.7)</td></tr><tr><td>Urology</td><td>18 (3.6)</td></tr><tr><td>Others</td><td>137 (27.2)</td></tr><tr><td rowspan="4">Season</td><td>Jan - March</td><td>149 (29.6)</td></tr><tr><td>April–June</td><td>112 (22.2)</td></tr><tr><td>July - Sept</td><td>112 (22.2)</td></tr><tr><td>Oct - Dec</td><td>131 (26.0)</td></tr></table> |
5003894356e4bd57978977ebd4bf77eb9f884d1779801bc628df04c3556d3862.png | simple | <table><tr><td>Taxon</td><td>Species</td><td>Isoenzyme</td><td>Sequence identity, %</td></tr><tr><td>Mammals</td><td><i>Homo sapiens - Microcebus murinus</i></td><td>GAPD-1</td><td>91</td></tr><tr><td></td><td><i>Homo sapiens - Callitrix jacchus</i></td><td>GAPD-2</td><td>94</td></tr><tr><td>Teleosts</td><td><i>Tetraodon nigroviridis - Takifugu rubripes</i></td><td>GAPD-1</td><td>94</td></tr><tr><td></td><td><i>Tetraodon nigroviridis - Takifugu rubripes</i></td><td>GAPD-2</td><td>92</td></tr><tr><td>Insects</td><td><i>Drosophila ananassae - Drosophila virilis</i></td><td>GAPD</td><td>87</td></tr></table> |
32592d8cd7361d00991bf6f2ce5bf26372c84211ea9b8b7a752fe599e53157e0.png | complex | <table><tr><td>Predictor variable</td><td>Odds Ratio</td><td><i>p</i>-value</td><td>95% Confidence Interval</td></tr><tr><td colspan="4">Health declaration (<i>N</i> = 1459)</td></tr><tr><td> IVQ33/ITQ50: confidence</td><td>0.69</td><td>0.017</td><td>(0.51, 0.94)</td></tr><tr><td colspan="4">Depression coding: IVQ33ITQ50 model (<i>N</i> = 1459)</td></tr><tr><td> Non-professional background</td><td>4.39</td><td>0.010</td><td>(1.44, 13.40)</td></tr><tr><td> IVQ33/ITQ50: confidence</td><td>0.52</td><td>0.013</td><td>(0.31, 0.87)</td></tr><tr><td colspan="4">Depression coding: ITQ100 model (<i>N</i> = 1619)</td></tr><tr><td> Non-professional background</td><td>4.78</td><td>0.001</td><td>(1.97, 11.60)</td></tr></table> |
59f7b3d60a61645c57fb11622a9dc0782922e68ab55f97840fdf2e4a75e1cf96.png | complex | <table><tr><td rowspan="2">Algorithm</td><td rowspan="2">Results </td><td colspan="5">Training </td><td colspan="5">Testing </td></tr><tr><td><i>Gmean</i> (%) </td><td>TN</td><td>FP</td><td>TP</td><td>FN</td><td><i>Gmean</i> (%) </td><td>TN</td><td>FP</td><td>TP</td><td>FN</td></tr><tr><td rowspan="4">RA-PSO</td><td>AVG </td><td><i>99.90</i></td><td><i>5110</i></td><td><i>30</i></td><td><i>20</i></td><td><i>0</i></td><td><i>98.59</i></td><td><i>5106</i></td><td><i>34</i></td><td><i>19</i></td><td><i>1</i></td></tr><tr><td>MAX </td><td>99.91</td><td>5111</td><td>29</td><td>20</td><td>0</td><td>99.86</td><td>5107</td><td>33</td><td>20</td><td>0</td></tr><tr><td>MIN </td><td>99.87</td><td>5107</td><td>33</td><td>20</td><td>0</td><td>97.33</td><td>5103</td><td>37</td><td>19</td><td>1</td></tr><tr><td>STDEV </td><td>1.15</td><td> </td><td> </td><td> </td><td> </td><td>1.33</td><td> </td><td> </td><td> </td><td> </td></tr></table> |
e160d6a60f6a4221953eca88816f1885a85329b849647d390ef4ddab8146e880.png | simple | <table><tr><td>Client Mode</td><td>Indicates</td><td>Server Mode</td><td>Indicates</td></tr><tr><td>INIT</td><td>Initialization.</td><td>INIT</td><td>Initialization.</td></tr><tr><td>SPEAKER</td><td>Client is speaker.</td><td>SPEAKERS_TURN</td><td>Signal creation</td></tr><tr><td>HEARER</td><td>Client is hearer.</td><td>HEARERS_TURN</td><td>Signal recognition</td></tr><tr><td>FEEDBACK</td><td>Client is receiving feedback.</td><td>FEEDBACK</td><td>Clients are receiving feedback.</td></tr></table> |
fca01aff07b98f11c61013123e858f5d1b9cb556ab997c05b79c44c72dd024ce.png | complex | <table><tr><td> </td><td>Before treatment</td><td>After treatment</td><td><i>n </i></td><td><i>P </i></td></tr><tr><td colspan="5">Epidermal thickness average (<i>μ</i>m)</td></tr><tr><td>LN</td><td>39.34 (SD 7.83)</td><td>43.37 (SD 9.40)</td><td>16</td><td>0.09</td></tr><tr><td>PS</td><td>38.26 (SD 6.52)</td><td>42.28 (SD 8.24)</td><td>15</td><td>0.13</td></tr><tr><td colspan="5">Grenz zone thickness average (<i>μ</i>m)</td></tr><tr><td>LN</td><td>61.41 (SD 29.50)</td><td>64.37 (SD 18.07)</td><td>16</td><td>0.71</td></tr><tr><td>PS</td><td>71.08 (SD 25.98)</td><td>80.58 (SD 37.04)</td><td>15</td><td>0.36</td></tr><tr><td colspan="5">Pigment intensity score</td></tr><tr><td>LN</td><td>75.42 (DP 13.27)</td><td>71.88 (DP 17.68)</td><td>16</td><td>0.54</td></tr><tr><td>PS</td><td>69.55 (DP 11.04)</td><td>58.89 (DP 12.39)</td><td>15</td><td>0.025</td></tr></table> |
1cee65642409c68e1a47ef2b37dd2fa13fe76f2ad562926c1af0adbbf8ffa54f.png | complex | <table><tr><td rowspan="2">Specimen Source Treatment</td><td rowspan="2">n</td><td colspan="2">MIC Range</td><td rowspan="2">MIC<sub>50</sub> (μg/mL)</td><td rowspan="2">MIC<sub>90</sub> (μg/mL)</td></tr><tr><td>Minimum (μg/mL)</td><td>Maximum (μg/mL)</td></tr><tr><td colspan="6">Urogenital</td></tr><tr><td> Gepotidacin 1500 mg</td><td>30</td><td>≤0.06</td><td>1</td><td>0.12</td><td>0.5</td></tr><tr><td> Gepotidacin 3000 mg</td><td>39</td><td>≤0.06</td><td>1</td><td>0.25</td><td>0.5</td></tr><tr><td> Gepotidacin total</td><td>69</td><td>≤0.06</td><td>1</td><td>0.12</td><td>0.5</td></tr><tr><td colspan="6">Pharyngeal</td></tr><tr><td> Gepotidacin 1500 mg</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td></tr><tr><td> Gepotidacin 3000 mg</td><td>2<sup>a</sup></td><td>≤0.06</td><td>0.12</td><td>...</td><td>...</td></tr><tr><td> Gepotidacin total</td><td>2<sup>a</sup></td><td>≤0.06</td><td>0.12</td><td>...</td><td>...</td></tr><tr><td colspan="6">Rectal</td></tr><tr><td> Gepotidacin 1500 mg</td><td>1</td><td>0.12</td><td>0.12</td><td>...</td><td>...</td></tr><tr><td> Gepotidacin 3000 mg</td><td>2</td><td>0.12</td><td>0.25</td><td>...</td><td>...</td></tr><tr><td> Gepotidacin total</td><td>3</td><td>0.12</td><td>0.25</td><td>...</td><td>...</td></tr></table> |
ed2feadd119f80d33edd3171ac4a2d70a8b4a441a66a0fbf5fcffed167e81544.png | complex | <table><tr><td></td><td></td><td colspan="4">Korean sample</td><td colspan="4">STAR*D</td></tr><tr><td>Gene</td><td>Gene full name</td><td colspan="2">SNPs with <i>p</i> < 0.05</td><td>SNPs (tot N)</td><td>Permuted <i>p</i></td><td colspan="2">SNPs with <i>p</i> < 0.05</td><td>SNPs (tot N)</td><td>Permuted <i>p</i></td></tr><tr><td></td><td></td><td>N true</td><td>N false</td><td colspan="2">/</td><td>N true</td><td>N false</td><td colspan="2">/</td></tr><tr><td>A</td><td></td><td></td><td></td><td colspan="2"></td><td></td><td></td><td colspan="2"></td></tr><tr><td><i>AGBL1</i></td><td>ATP/GTP Binding Protein-Like 1</td><td>268 (7 %)</td><td>3454 (92 %)</td><td>3722</td><td><0.00001</td><td>65 (9 %)</td><td>601 (90 %)</td><td>656</td><td>8.9e-5</td></tr><tr><td><i>CYB5A</i></td><td>Cytochrome B5 Type A (Microsomal)</td><td>216 (58 %)</td><td>152 (41 %)</td><td>368</td><td><0.00001</td><td>25 (37 %)</td><td>41 (62 %)</td><td>66</td><td>3.9e-5</td></tr><tr><td><i>MTRF1L</i></td><td>Mitochondrial Translational Release Factor 1-Like</td><td>85 (47 %)</td><td>95 (52 %)</td><td>180</td><td><0.00001</td><td>10 (38 %)</td><td>16 (61 %)</td><td>26</td><td>0.0003</td></tr><tr><td><i>RGS22</i></td><td>Regulator Of G-Protein Signaling 22</td><td>129 (29 %</td><td>311 (70 %)</td><td>440</td><td><0.00001</td><td>25 (46 %)</td><td>29 (53 %)</td><td>104</td><td>0.0001</td></tr><tr><td>B</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td><i>CTNNA3</i></td><td>Catenin (Cadherin-Associated Protein), Alpha 3</td><td>446 (6 %)</td><td>6628 (93 %)</td><td>7074</td><td><0.00001</td><td>118 (11 %)</td><td>952 (88 %)</td><td>1070</td><td><0.00001</td></tr><tr><td><i>HS6ST3</i></td><td>Heparan Sulfate 6-O-Sulfotransferase 3</td><td>305 (15 %)</td><td>1626 (84 %)</td><td>1931</td><td><0.00001</td><td>50 (14 %)</td><td>298 (85 %)</td><td>348</td><td>8.9e-5</td></tr></table> |
3902c29d6c681f5b52376d862882994ff5d148a4d8acecb6249903b54e6882fd.png | simple | <table><tr><td></td><td>Pre-dictive ethics</td><td>Iterative ethics</td></tr><tr><td>1</td><td>Ethical risks are generally predictable</td><td>Ethical risks may NOT be predictable</td></tr><tr><td>2</td><td>Ethical procedures should be pre-specified - Ethics as ‘requirement’</td><td>Ethical procedures should be emergent to take into account the unfolding context - Ethics as ‘process’</td></tr><tr><td>3</td><td>Treats participants as being ‘subject to’ research</td><td>Treats participants as being ‘subjective participants within’ research</td></tr><tr><td>4</td><td>Ethics reviews aim to protect participants</td><td>Ethics reviews aim to help researchers to think sensitively about how to maintain an ethical stance towards and with research participants</td></tr><tr><td>5</td><td>Ethics reviews aim to evaluate researchers</td><td>Ethics reviews aim to work with researchers to explore ethical concerns</td></tr><tr><td>6</td><td>Ethics reviews ‘apply’ codes of conduct and treat ethics as a set of ‘accountable standards’</td><td>Ethics reviews analyse ethical concerns with researchers in relation to the specific research context</td></tr><tr><td>7</td><td>Researchers treated as independent from practices of data collection and regarded as implementing a research protocol</td><td>Researchers seen as reflexive participants within research</td></tr><tr><td>8</td><td>Work with a binary of ‘ethical’/‘non-ethical’</td><td>Treat ethical problems as multidimensional and contextually framed</td></tr></table> |
51cecc689a8dad0523be87c84a660d1e517cf5594e93bbd42a50bebac0d2f485.png | complex | <table><tr><td>Items</td><td>Criteria of remission</td><td>Remitted</td><td>Non-remitted</td><td>Statistics (df)/Cohen’s d</td></tr><tr><td rowspan="3">MMSE Total score</td><td>SWGC*</td><td>26.80 (2.71)</td><td>25.02 (4.42)</td><td>t(110) = 2.576,p = .011/0.485</td></tr><tr><td>PANSS PNS**</td><td>27.33 (2.61)</td><td>25.15 (4.06)</td><td>t(110) = 3.033,p = .003/0.638</td></tr><tr><td>PANSS TS***</td><td>27.62 (2.47)</td><td>25.40 (3.93)</td><td>t(110) = 2.713,p = .008/0.676</td></tr><tr><td rowspan="3">BACS list learning</td><td>SWGC*</td><td>9.31 (4.77)</td><td>9.92 (4.59)</td><td>t(99) = −.652,p = 0.516/NA°</td></tr><tr><td>PANSS PNS**</td><td>9.10 (5.24)</td><td>9.89 (4.35)</td><td>t(99) = −.806,p = 0.422/NA°</td></tr><tr><td>PANSS TS***</td><td>8.62 (5.42)</td><td>9.94 (4.38)</td><td>t(99) = 1.236,p = 0.219/NA°</td></tr><tr><td rowspan="3">BACS Digit sequencing task</td><td>SWGC*</td><td>14.75 (6.06)</td><td>11.26 (6.19)</td><td>t(99) = 2.86,p = .005/0.571</td></tr><tr><td>PANSS PNS**</td><td>16.30 (5.65)</td><td>11.23 (6.01)</td><td>t(99) = 4.112p < .0001/0.969</td></tr><tr><td>PANSS TS***</td><td>17.31 (5.47)</td><td>11.56 (5.98)</td><td>t(99) = 4.247p < .0001/1.00</td></tr><tr><td rowspan="3">BACS Verbal Fluency/category istances</td><td>SWGC*</td><td>9.89 (4.98)</td><td>8.10 (4.96)</td><td>t(99) = 1.801,p = .075/0.360</td></tr><tr><td>PANSS PNS**</td><td>10.66 (4.27)</td><td>8.10 (5.20)</td><td>t(99) = 2.479,p = .014/0.538</td></tr><tr><td>PANSS TS***</td><td>10.75 (4.21)</td><td>8.40 (5.16)</td><td>t(99) = 2.056,p = .042/0.499</td></tr><tr><td rowspan="3">BACS Verbal FluencyControlled Oral Words ass.test</td><td>SWGC*</td><td>15.05 (3.89)</td><td>14.50 (5.49)</td><td>t(99) = 0.569 p = .571/NA°</td></tr><tr><td>PANSS PNS**</td><td>15.46 (4.31)</td><td>14.41 (4.96)</td><td>t(99) = 1.061 p = .27/NA°</td></tr><tr><td>PANSS TS***</td><td>15.21 (4.89)</td><td>14.63 (4.73)</td><td>t(99) = 0.536 p = .593/NA°</td></tr><tr><td rowspan="3">BACS Symbol coding</td><td>SWGC*</td><td>32.60 (13.64)</td><td>28.60 (12.29)</td><td>t(99) = 1.549,p = 0.125/NA°</td></tr><tr><td>PANSS PNS**</td><td>36.10 (12.87)</td><td>27.67 (12.29)</td><td>t(99) = 3.228,p = .002/0.669</td></tr><tr><td>PANSS TS***</td><td>37.85 (12.48)</td><td>28.20 (12.43)</td><td>t(99) = 3.263,p = .001/0.774</td></tr><tr><td rowspan="3">BACS Tower of London</td><td>SWGC*</td><td>11.38 (5.98)</td><td>9.5 (6.53)</td><td>t(99) = 1.445,p = 0.152/NA°</td></tr><tr><td>PANSS PNS**</td><td>12.80 (5.44)</td><td>9.25 (6.33)</td><td>t(99) = 2.815,p = .006/0.601</td></tr><tr><td>PANSS TS***</td><td>13.16 (5.65)</td><td>9.60 (6.21)</td><td>t (99) = 2.536,p = .013/0.599</td></tr></table> |
4fc3a4f9ecf80d858a929d1290e30af916fab7910088874e22269a360b662c16.png | simple | <table><tr><td>Patient</td><td>Angiographic findings*</td><td>gradient reduction**</td><td>Number of additional Revisions</td><td>Follow up</td></tr><tr><td>1</td><td>HV, PV, SMV occluded</td><td>17 → 8</td><td>2</td><td>2 years</td></tr><tr><td>2</td><td>HV occluded</td><td>30 → 7</td><td>1</td><td>4 years</td></tr><tr><td>3</td><td>HV occluded</td><td>23 → 10</td><td>3</td><td>2 years</td></tr><tr><td>4</td><td>HV occluded</td><td>29 → 12</td><td>2</td><td>12 years</td></tr><tr><td>5</td><td>HV occluded</td><td>46 → 6</td><td>1</td><td>5 years</td></tr><tr><td>6</td><td>HV, PV, IVC occluded</td><td>35 → 6</td><td>8</td><td>7 years</td></tr><tr><td>7</td><td>HV occluded</td><td>32 → 6</td><td>4</td><td>11 years</td></tr><tr><td>8</td><td>HV occluded</td><td>25 → 10</td><td>1</td><td>3 years</td></tr><tr><td>9</td><td>HV occluded</td><td>20 → 8</td><td>2</td><td>6 years</td></tr><tr><td>10</td><td>HV occluded</td><td>32 → 3</td><td>0</td><td>3 years</td></tr><tr><td>11</td><td>HV occluded</td><td>31 → 9</td><td>3</td><td>3 years</td></tr><tr><td>12</td><td>HV occluded</td><td>10 → 4</td><td>6</td><td>10 years</td></tr><tr><td>13</td><td>HV occluded</td><td>38 → 6</td><td>0</td><td>1/2 year</td></tr></table> |
8fcf11d824acb1a5a81f8caa09150d6828bcc09d5393c920f817dd05bf2e6985.png | simple | <table><tr><td></td><td>Current</td><td>Desired</td><td>Gap</td><td>Academic Gap</td><td>Community Gap</td></tr><tr><td>Estimating incremental risk incurred by conditional risk factors</td><td>3.84</td><td>4.59</td><td>0.75</td><td>0.83</td><td>0.67</td></tr><tr><td>Estimating cardiovascular risk in primary prevention</td><td>4.14</td><td>4.75</td><td>0.61</td><td>0.73</td><td>0.48</td></tr><tr><td>Estimating incremental risk incurred by predisposing risk factors</td><td>4.07</td><td>4.67</td><td>0.60</td><td>0.68</td><td>0.52</td></tr><tr><td>Identifying <underline>conditional</underline> cardiovascular risk factors</td><td>4.07</td><td>4.65</td><td>0.59</td><td>0.67</td><td>0.51</td></tr><tr><td>Estimating cardiovascular risk in secondary prevention</td><td>4.29</td><td>4.75</td><td>0.46</td><td>0.56</td><td>0.36</td></tr><tr><td>Identifying predisposing cardiovascular risk factors</td><td>4.41</td><td>4.78</td><td>0.37</td><td>0.45</td><td>0.29</td></tr><tr><td>Identifying <underline>major independent</underline> cardiovascular risk factors</td><td>4.49</td><td>4.79</td><td>0.30</td><td>0.37</td><td>0.23</td></tr></table> |
09bf4fda8d33e0ae398705d1700edc734c72fc3965e359cd8badfcd343fe5eb3.png | simple | <table><tr><td></td><td>Z</td><td>J</td><td>Milk</td><td>Where</td><td>Store</td><td>Pig</td><td>Past</td><td>Green</td><td>Finish</td><td>Bathroom</td><td>Hungry</td><td>Blue</td></tr><tr><td>Z</td><td>100%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td></tr><tr><td>J</td><td>-</td><td>95%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>5%</td></tr><tr><td>Milk</td><td>-</td><td>-</td><td>100%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Where</td><td>-</td><td>2%</td><td>-</td><td>94%</td><td>-</td><td>-</td><td>4%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Store</td><td>-</td><td>5%</td><td>-</td><td>-</td><td>95%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Pig</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>100%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Past</td><td>-</td><td>-</td><td>-</td><td>-</td><td>3%</td><td>-</td><td>92%</td><td>-</td><td>4%</td><td>-</td><td>1%</td><td>-</td></tr><tr><td>Green</td><td>-</td><td>-</td><td>-</td><td>-</td><td>7%</td><td>-</td><td>-</td><td>93%</td><td>-</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Finish</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>100%</td><td>-</td><td>-</td><td>-</td></tr><tr><td>Bathroom</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>100%</td><td>-</td><td>-</td></tr><tr><td>Hungry</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>100%</td><td>-</td></tr><tr><td>Blue</td><td>-</td><td>-</td><td>-</td><td>2%</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>-</td><td>98%</td></tr></table> |
9ec57b6ef0edba41ac28e5e681fbd8046639e0315ad6a1a742c0fdbe6c4e1da7.png | complex | <table><tr><td rowspan="2">Substances</td><td>Retention time</td><td>OLALPZER</td><td>OLALPVIT</td></tr><tr><td>(min)</td><td>Area (%)</td><td>Area (%)</td></tr><tr><td><i>α</i>-Thujene</td><td>12.6</td><td>3.7</td><td>-</td></tr><tr><td><i>α</i>-Pinene</td><td>12.9</td><td>1.7</td><td>10.1</td></tr><tr><td>Camphene</td><td>13.6</td><td>0.2</td><td>-</td></tr><tr><td>Sabinene</td><td>14.7</td><td>13.8</td><td>1.2</td></tr><tr><td><i>β</i>-Pinene</td><td>14.8</td><td>3.0</td><td>35.3</td></tr><tr><td><i>β</i>-Myrcene</td><td>15.4</td><td>1.1</td><td>-</td></tr><tr><td>Phellandrene</td><td>16.1</td><td>0.3</td><td>-</td></tr><tr><td><i>α</i>-Terpinene</td><td>16.6</td><td>4.0</td><td>-</td></tr><tr><td><i>ρ</i>-Cymene</td><td>16.9</td><td>4.8</td><td>-</td></tr><tr><td>Limonene</td><td>17.1</td><td>1.8</td><td>1.5</td></tr><tr><td>1,8-Cineol</td><td>17.2</td><td>15.3</td><td>-</td></tr><tr><td><i>α</i>-Terpinolene</td><td>-</td><td>2.0</td><td>-</td></tr><tr><td><i>cis</i>-Sabinene</td><td>20</td><td>2.2</td><td>-</td></tr><tr><td>Terpinen-4-ol</td><td>23.2</td><td>19.7</td><td>-</td></tr><tr><td><i>α</i>-Cubebene</td><td>29.0</td><td>-</td><td>2.1</td></tr><tr><td>Copaene</td><td>30</td><td>-</td><td>2.4</td></tr><tr><td><i>β</i>-Cubebene</td><td>30.4</td><td>-</td><td>2.4</td></tr><tr><td><i>β</i>-Caryophyllene</td><td>31.5</td><td>3.2</td><td>1.0</td></tr><tr><td><i>β</i>-Gurjunene</td><td>32.4</td><td>-</td><td>1.7</td></tr><tr><td>Aromadendrene</td><td>32.8</td><td>-</td><td>0.7</td></tr><tr><td><i>cis</i>-Muurola-4(14),5-diene</td><td>33.1</td><td>-</td><td>0.6</td></tr><tr><td>Germacrene-D</td><td>33.4</td><td>-</td><td>0.6</td></tr><tr><td>epi-Bicyclosesquiphellandrene</td><td>33.8</td><td>-</td><td>1.0</td></tr><tr><td>epi-Cubebol</td><td>33.9</td><td>-</td><td>5.0</td></tr><tr><td>Calamenene</td><td>34.7</td><td>-</td><td>2.0</td></tr><tr><td>Cadina-1(2),4-diene</td><td>35.0</td><td> </td><td>0.8</td></tr><tr><td>Viridiflorol</td><td>37.2</td><td> </td><td>1.75</td></tr><tr><td>1-epi-Cubenol</td><td>37.8</td><td> </td><td>1.43</td></tr><tr><td>1,10-di-epi-Cubenol</td><td>38.2</td><td> </td><td>1.24</td></tr><tr><td>Caryophyllene oxide</td><td>36.5</td><td>1.9</td><td>-</td></tr><tr><td>Others</td><td>-</td><td>21.2</td><td>27.2</td></tr></table> |
af0c9d4830a122941016485cc16a754e888dd7b62bf43f013507b2e99589250a.png | complex | <table><tr><td>Patient</td><td>Age</td><td>First presentation</td><td>Patient interval</td><td>Residential area<sup>a</sup></td><td>Full-time job</td><td>Cohabitant children</td></tr><tr><td colspan="7">Pre-disaster</td></tr><tr><td> 1</td><td>(50–65]</td><td>Apr.-Jun. 2007</td><td>120 months</td><td>Voluntary evacuation zone</td><td>Yes</td><td>No</td></tr><tr><td> 2</td><td>(65-</td><td>Apr.-Jun. 2008</td><td>48 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 3</td><td>(50–65]</td><td>Sep.-Nov. 2008</td><td>18 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 4</td><td>(65-</td><td>Dec. 2008-Feb. 2009</td><td>120 months</td><td>Non-evacuation zone</td><td>No</td><td>Yes</td></tr><tr><td> 5</td><td>−50]</td><td>Sep.-Nov. 2009</td><td>36 months</td><td>Mandatory evacuation zone</td><td>Yes</td><td>Yes</td></tr><tr><td colspan="7">Post-disaster</td></tr><tr><td> 1</td><td>(50–65]</td><td>Dec. 2011-Feb. 2012</td><td>24 months</td><td>Non-evacuation zone</td><td>No</td><td>Yes</td></tr><tr><td> 2</td><td>(65-</td><td>Jun.-Aug. 2012</td><td>18 months</td><td>Non-evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 3</td><td>(50–65]</td><td>Sep.-Nov. 2012</td><td>17 months</td><td>Voluntary evacuation zone</td><td>Yes</td><td>No</td></tr><tr><td> 4</td><td>(65-</td><td>Sep.-Nov. 2012</td><td>12 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 5</td><td>−50]</td><td>Dec. 2012-Feb. 2013</td><td>12 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 6</td><td>(65-</td><td>Dec. 2012-Feb. 2013</td><td>25 months</td><td>Voluntary evacuation zone</td><td>Yes</td><td>No</td></tr><tr><td> 7</td><td>(65-</td><td>Mar.-May 2013</td><td>24 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 8</td><td>(65-</td><td>Mar.-May 2014</td><td>12 months</td><td>Non-evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 9</td><td>−50]</td><td>Jun.-Aug. 2014</td><td>13 months</td><td>Non-evacuation zone</td><td>Yes</td><td>Yes</td></tr><tr><td> 10</td><td>(65-</td><td>Sep.-Nov. 2014</td><td>24 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 11</td><td>(65-</td><td>Sep.-Nov. 2014</td><td>84 months</td><td>Voluntary evacuation zone</td><td>No</td><td>Yes</td></tr><tr><td> 12</td><td>−50]</td><td>Sep.-Nov. 2014</td><td>24 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 13</td><td>(65-</td><td>Dec. 2014-Feb. 2015</td><td>24 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 14</td><td>(50–65]</td><td>Jun.-Aug. 2015</td><td>24 months</td><td>Mandatory evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 15</td><td>(65-</td><td>Sep.-Nov. 2015</td><td>24 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 16</td><td>(65-</td><td>Sep.-Nov. 2015</td><td>120 months</td><td>Voluntary evacuation zone</td><td>No</td><td>No</td></tr><tr><td> 17</td><td>(50–65]</td><td>Sep.-Nov. 2015</td><td>13 months</td><td>Mandatory evacuation zone</td><td>No</td><td>Yes</td></tr><tr><td> 18</td><td>(50–65]</td><td>Dec. 2015-Feb. 2016</td><td>12 months</td><td>Voluntary evacuation zone</td><td>Yes</td><td>No</td></tr></table> |
57c1d187227f79836e9728f8bf88b636cd7953142369a3e3056e40734767abe9.png | simple | <table><tr><td> </td><td>Treatment group</td><td>Control group</td><td>p-value</td></tr><tr><td>Stage Ib</td><td>15 (1)</td><td>16 (2)</td><td>-</td></tr><tr><td>Stage II</td><td>1</td><td>0</td><td>-</td></tr><tr><td>Total gastrectomy</td><td>4</td><td>3</td><td>-</td></tr><tr><td>Distal gastrectomy</td><td>12 (1)</td><td>13 (2)</td><td>-</td></tr><tr><td>Sex (M:F)</td><td>13 (2):3</td><td>13 (1):3</td><td>-</td></tr><tr><td>Age (year, mean ± SD, median)</td><td>53.75±10.25, 54</td><td>54.87±11.51, 52.5</td><td>0.77</td></tr><tr><td>BMI (mean ± SD)</td><td>23.21±2.09</td><td>23.57±1.93</td><td>0.63</td></tr><tr><td>Systolic BP (mmHg, mean ± SD)</td><td>112.88±9.23</td><td>108.88±9.84</td><td>0.24</td></tr><tr><td>Diastolic BP (mmHg, mean ± SD)</td><td>70.75±7.69</td><td>72.38±8.16</td><td>0.57</td></tr><tr><td>Pulse rates (mean ± SD)</td><td>73.06±12.89</td><td>74.94±10.88</td><td>0.65</td></tr></table> |
9315191684afccbe1f93052fcaabac3c1dae94f26a7c1694f054364dde8be815.png | simple | <table><tr><td>Top</td><td>Regulator</td><td>Out- degree</td><td>Supported by<sup>a</sup></td></tr><tr><td>1</td><td>hsa-miR-590-3p</td><td>320</td><td>-</td></tr><tr><td>2</td><td>hsa-miR-548c-3p</td><td>302</td><td>-</td></tr><tr><td>3</td><td>hsa-miR-570</td><td>243</td><td>-</td></tr><tr><td>4</td><td>hsa-miR-340</td><td>242</td><td>-</td></tr><tr><td>5</td><td>hsa-miR-495</td><td>218</td><td>-</td></tr><tr><td>6</td><td>hsa-miR-106a<sup>b</sup></td><td>207</td><td>PMID: 19209007</td></tr><tr><td>7</td><td>hsa-miR-106b<sup>b</sup></td><td>202</td><td>-</td></tr><tr><td>8</td><td>hsa-miR-20a<sup>b</sup></td><td>201</td><td>PMID: 16266980</td></tr><tr><td>9</td><td>hsa-miR-20b<sup>b</sup></td><td>200</td><td>-</td></tr><tr><td>10</td><td>hsa-miR-944</td><td>200</td><td>-</td></tr><tr><td>1</td><td>MYC</td><td>116</td><td>PMID: 11720740</td></tr><tr><td>2</td><td>TP53</td><td>95</td><td>PMID: 12619108</td></tr><tr><td>3</td><td>E2F1</td><td>73</td><td>PMID: 22803943</td></tr><tr><td>4</td><td>TFAP2A</td><td>64</td><td>PMID: 22143938</td></tr><tr><td>5</td><td>SP1</td><td>61</td><td>PMID: 22158040</td></tr><tr><td>6</td><td>JUN</td><td>59</td><td>-</td></tr><tr><td>7</td><td>E2F4</td><td>50</td><td>PMID: 19473719</td></tr><tr><td>8</td><td>HIF1A</td><td>48</td><td>PMID: 22115707</td></tr><tr><td>9</td><td>NFKB1</td><td>48</td><td>-</td></tr><tr><td>10</td><td>STAT1</td><td>44</td><td>PMID: 17348819</td></tr></table> |
dd8c6a91539367d95688a0379370c926124cc282b75588b63dad2b446494cd63.png | complex | <table><tr><td>Sample</td><td>Extent of ageing (weeks)</td><td colspan="4">Difference in colour (aged versus unaged)</td><td colspan="2">Mean tensile properties</td></tr><tr><td> </td><td> </td><td>ΔE<sub>00</sub>*</td><td>ΔL*</td><td>Δa*</td><td>Δb*</td><td>Breaking load (N)</td><td>Extension (%)</td></tr><tr><td>WU</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>ND<sup>a</sup></td><td>ND</td></tr><tr><td> </td><td>1</td><td>1.14</td><td>0.05</td><td>−0.40</td><td>1.38</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>2</td><td>1.33</td><td>0.32</td><td>−0.48</td><td>1.58</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>3</td><td>1.75</td><td>0.17</td><td>−0.61</td><td>2.16</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>4</td><td>2.44</td><td>−0.22</td><td>−0.72</td><td>3.17</td><td>ND</td><td>ND</td></tr><tr><td>SU</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>70.2 (4.9)<sup>b</sup></td><td>28.2 (1.7)<sup>b</sup></td></tr><tr><td> </td><td>1</td><td>1.04</td><td>−0.06</td><td>−0.32</td><td>1.00</td><td>64.2 (4.4)</td><td>25.2 (0.8)</td></tr><tr><td> </td><td>2</td><td>1.57</td><td>0.00</td><td>−0.44</td><td>1.54</td><td>65.5 (4.8)</td><td>24.9 (2.5)</td></tr><tr><td> </td><td>3</td><td>2.16</td><td>−0.48</td><td>−0.54</td><td>2.17</td><td>62.3 (4.7)</td><td>24.8 (2.7)</td></tr><tr><td> </td><td>4</td><td>2.59</td><td>−0.40</td><td>−0.57</td><td>2.70</td><td>61.6 (4.3)</td><td>21.7 (2.1)</td></tr><tr><td>AU</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>239.9 (43.1)</td><td>3.9 (0.5)</td></tr><tr><td> </td><td>1</td><td>2.39</td><td>−2.17</td><td>0.67</td><td>2.78</td><td>255.5 (38.1)</td><td>3.7 (0.5)</td></tr><tr><td> </td><td>2</td><td>3.08</td><td>−2.82</td><td>1.05</td><td>3.43</td><td>262.8 (47.3)</td><td>3.8 (0.5)</td></tr><tr><td> </td><td>3</td><td>3.03</td><td>−1.63</td><td>1.39</td><td>4.22</td><td>250.0 (40.3)</td><td>3.9 (0.6)</td></tr><tr><td> </td><td>4</td><td>3.95</td><td>−2.64</td><td>1.76</td><td>5.29</td><td>248.8 (28.9)</td><td>3.5 (0.5)</td></tr><tr><td>CU</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>117.1 (9.2)</td><td>9.1 (0.8)</td></tr><tr><td> </td><td>1</td><td>0.62</td><td>−0.15</td><td>−0.10</td><td>0.61</td><td>101.9 (15.7)</td><td>8.2 (1.0)</td></tr><tr><td> </td><td>2</td><td>1.20</td><td>0.06</td><td>−0.06</td><td>1.26</td><td>107.2 (11.6)</td><td>8.2 (0.7)</td></tr><tr><td> </td><td>3</td><td>1.52</td><td>−0.84</td><td>−0.07</td><td>1.48</td><td>107.1 (8.3)</td><td>8.6 (0.5)</td></tr><tr><td> </td><td>4</td><td>1.82</td><td>−0.28</td><td>−0.06</td><td>1.92</td><td>108.2 (11.0)</td><td>8.1 (0.5)</td></tr><tr><td>Wp1</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>1</td><td>ND</td><td>ND</td><td>ND</td><td>ND</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>2</td><td>2.74</td><td>−0.50</td><td>−0.39</td><td>2.73</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>3</td><td>3.64</td><td>0.42</td><td>−0.46</td><td>3.70</td><td>ND</td><td>ND</td></tr><tr><td> </td><td>4</td><td>5.70</td><td>3.33</td><td>−0.62</td><td>5.21</td><td>ND</td><td>ND</td></tr><tr><td>Sp1</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>62.9 (4.9)</td><td>25.0 (2.6)</td></tr><tr><td> </td><td>1</td><td>1.07</td><td>−0.61</td><td>−0.17</td><td>1.13</td><td>55.6 (6.1)</td><td>19.7 (1.4)</td></tr><tr><td> </td><td>2</td><td>1.78</td><td>−0.31</td><td>−0.30</td><td>1.98</td><td>46.0 (3.7)</td><td>14.5 (0.7)</td></tr><tr><td> </td><td>3</td><td>2.15</td><td>0.25</td><td>−0.41</td><td>2.37</td><td>34.2 (9.4)</td><td>13.2 (1.5)</td></tr><tr><td> </td><td>4</td><td>3.27</td><td>2.02</td><td>−0.39</td><td>3.24</td><td>33.2 (6.1)</td><td>10.1 (1.8)</td></tr><tr><td>Ac1</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>105.9 (18.3)</td><td>2.1 (0.3)</td></tr><tr><td> </td><td>1</td><td>3.04</td><td>0.24</td><td>0.11</td><td>3.17</td><td>14.6 (4.9)</td><td>1.8 (0.4)</td></tr><tr><td> </td><td>2</td><td>4.54</td><td>−0.37</td><td>0.63</td><td>4.64</td><td>6.5 (1.9)</td><td>1.0 (0.3)</td></tr><tr><td> </td><td>3</td><td>5.33</td><td>−0.68</td><td>1.20</td><td>5.34</td><td>ND<sup>c</sup></td><td>ND<sup>c</sup></td></tr><tr><td> </td><td>4</td><td>4.96</td><td>−2.00</td><td>1.08</td><td>4.75</td><td>ND<sup>c</sup></td><td>ND<sup>c</sup></td></tr><tr><td>Cc1</td><td>0</td><td>0.00</td><td>0.00</td><td>0.00</td><td>0.00</td><td>68.3 (5.3)</td><td>6.9 (0.7)</td></tr><tr><td> </td><td>1</td><td>7.35</td><td>−4.23</td><td>0.30</td><td>6.92</td><td>29.5 (3.9)</td><td>4.9 (0.6)</td></tr><tr><td> </td><td>2</td><td>10.49</td><td>−4.68</td><td>1.29</td><td>10.55</td><td>13.0 (0.4)</td><td>3.7 (0.6)</td></tr><tr><td> </td><td>3</td><td>12.15</td><td>−5.71</td><td>2.29</td><td>12.24</td><td>7.7 (1.1)</td><td>3.5 (0.2)</td></tr><tr><td> </td><td>4</td><td>13.24</td><td>−6.72</td><td>3.02</td><td>13.22</td><td>6.2 (0.7)</td><td>3.5 (0.2)</td></tr></table> |
16a5d80965422425dc708e0da6ee3584e90340651f3b3a1b91f6628c54c970c3.png | simple | <table><tr><td>Symptom</td><td><i>n </i></td><td>%</td></tr><tr><td>Bloated stomach </td><td>56</td><td>61.5</td></tr><tr><td>Anemia</td><td>48</td><td>52.7</td></tr><tr><td>Weight loss</td><td>44</td><td>48.3</td></tr><tr><td>Diarrhea</td><td>36</td><td>39.6</td></tr><tr><td>Vomiting</td><td>18</td><td>19.8</td></tr><tr><td>Other symptoms/signs</td><td>31</td><td>34.1</td></tr></table> |
823527cb17c9a164c03dd2e9f7578f757af57ab5ab14a818c934eea4780cabf0.png | complex | <table><tr><td rowspan="2">Studies</td><td rowspan="2">Number of studies</td><td colspan="2">Heterogeneity test</td><td rowspan="2">Analysis model</td><td rowspan="2">OR (95% CI)</td><td colspan="2">Hypothesis test</td><td colspan="2">Begg's test</td><td colspan="2">Egger's test</td></tr><tr><td><i>Q</i></td><td><i>P</i></td><td><i>Z</i></td><td><i>P</i></td><td><i>Z</i></td><td><i>P</i></td><td><i>t</i></td><td><i>P</i></td></tr><tr><td>Overall</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>3-year OS</td><td>11</td><td>40.12</td><td>0.000</td><td>Random-effects model</td><td>1.33 (0.97–1.84)</td><td>1.74</td><td>0.081</td><td>0.31</td><td>0.755</td><td>0.59</td><td>0.572</td></tr><tr><td>5-year OS</td><td>10</td><td>41.72</td><td>0.000</td><td>Random-effects model</td><td>1.38 (1.04–1.82)</td><td>2.26</td><td>0.024</td><td>1.25</td><td>0.210</td><td>0.96</td><td>0.364</td></tr><tr><td>Gastric cancer</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>3-year OS</td><td>6</td><td>11.40</td><td>0.044</td><td>Random-effects model</td><td>1.69 (1.28–2.25)</td><td>3.66</td><td>0.000</td><td>0.38</td><td>0.707</td><td>1.18</td><td>0.302</td></tr><tr><td>5-year OS</td><td>5</td><td>15.67</td><td>0.003</td><td>Random-effects model</td><td>1.74 (1.26–2.41)</td><td>3.32</td><td>0.001</td><td>2.20</td><td>0.027</td><td>7.28</td><td>0.005</td></tr><tr><td>Colorectal cancer</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>3-year OS</td><td>5</td><td>12.34</td><td>0.015</td><td>Random-effects model</td><td>0.84 (0.48–1.47)</td><td>0.62</td><td>0.536</td><td>0.73</td><td>0.462</td><td>0.46</td><td>0.679</td></tr><tr><td>5-year OS</td><td>5</td><td>17.38</td><td>0.002</td><td>Random-effects model</td><td>1.05 (0.67–1.65)</td><td>0.20</td><td>0.840</td><td>0.73</td><td>0.462</td><td>0.57</td><td>0.608</td></tr></table> |
6dc93c8499abb7954793fb7eff5f64abfb2f028ad48c2898a3af814db981832f.png | complex | <table><tr><td colspan="2">Variable</td><td>Non malignant N (%)</td><td>Malignant N (%)</td><td>COR (95% CI)</td><td>AOR (95% CI)</td></tr><tr><td rowspan="2">Sex</td><td>Male</td><td>171(92.4)</td><td>14(7.6)</td><td>1.05(0.56-1.94)</td><td></td></tr><tr><td>Female</td><td>613(92.7)</td><td>48(7.3)</td><td>1</td><td></td></tr><tr><td rowspan="7">Age in years</td><td>0-10</td><td>22(95.7)</td><td>1(4.3)</td><td>1.5(0.18-12.76)</td><td>1.31(.156-11.78)</td></tr><tr><td>11-20</td><td>231(97.1)</td><td>7(2.9)</td><td>1</td><td></td></tr><tr><td>21-30</td><td>236(91.8)</td><td>21(8.2)</td><td>2.94(1.23-7.04)</td><td>2.94(1.19-7.2)</td></tr><tr><td>31-40</td><td>133(91.7)</td><td>12(8.3)</td><td>2.98(1.14-7.75)</td><td>2.68(0.99-7.22)</td></tr><tr><td>41-50</td><td>91(91)</td><td>9(9)</td><td>3.26(1.18-9.03)</td><td>3.26(1.14-9.33)</td></tr><tr><td>51-60</td><td>48(88.9)</td><td>6(11.1)</td><td>4.13(1.33-12.82)</td><td>4.97(1.51-16.33)</td></tr><tr><td>>60</td><td>23(79.3)</td><td>6(20.7)</td><td>8.61(2.67-27.78)</td><td>10.96(3.15-38.1)</td></tr><tr><td rowspan="5">Size in cm</td><td>0-1.49</td><td>6(100)</td><td>0</td><td></td><td></td></tr><tr><td>1.5-1.99</td><td>3(100)</td><td>0</td><td></td><td></td></tr><tr><td>2-2.49</td><td>9(90.0)</td><td>1(10)</td><td>1.41(0.18-11.3)</td><td>02.87(0.22-15.98)</td></tr><tr><td>3-3.5</td><td>6(85.7)</td><td>1(14.3)</td><td>2.11(0.25-17.83)</td><td>2.36(0.236-23.70)</td></tr><tr><td>>3.5</td><td>760(92.7)</td><td>60(7.3)</td><td>1</td><td>1</td></tr><tr><td rowspan="6">Duration of enlargement in year</td><td><0.6 years</td><td>58(93.5)</td><td>4(6.5)</td><td>2.48(0.27-23.1)</td><td></td></tr><tr><td>0.6-1 year</td><td>115(85.8)</td><td>19(14.2)</td><td>5.95(0.77-46.0)</td><td></td></tr><tr><td>2-5 years</td><td>365(93.1)</td><td>27(6.9)</td><td>2.66(0.35-2018)</td><td></td></tr><tr><td>6-10 years</td><td>160(94.7)</td><td>9 (5.3)</td><td>2.03(0.25-16.50)</td><td></td></tr><tr><td>11-15 years</td><td>36(97.3)</td><td>1(2.7)</td><td>1</td><td></td></tr><tr><td>>15 years</td><td>50(96.2)</td><td>2(3.8)</td><td>1.44(0.13-16.50)</td><td></td></tr><tr><td rowspan="3">Type of enlargement</td><td>Solitary</td><td>78(78.8)</td><td>21(21.2)</td><td>9.154(3.75-22.35)</td><td>8.82(3.49-22.32)</td></tr><tr><td>MNG</td><td>468(93.2)</td><td>34(6.8)</td><td>2.47(1.08-5.66)</td><td>2.52(1.07-5.93)</td></tr><tr><td>Diffuse</td><td>238(97.1)</td><td>7(2.9)</td><td>1</td><td>1</td></tr></table> |
662c373d85737f7bc82ec4b06c1b4b24e467f61ebb0eda0dbbd5a1539f40efeb.png | simple | <table><tr><td> </td><td><i>P</i> value</td><td>OR</td><td>95% CI</td></tr><tr><td>Clavicle tunnel position (<i>x</i>-axis)</td><td>.454</td><td>1.19</td><td>0.77–2.00</td></tr><tr><td>Duration (within 5 days)</td><td>.002</td><td>1.82</td><td>1.32–2.87</td></tr><tr><td>Initial reduction (Good)</td><td>.003</td><td>59.71</td><td>6.71–1855.80</td></tr></table> |
ed6996374addf1cee0f3e84728fc0085689ad72af2043538cfb4cab92a7cda82.png | complex | <table><tr><td>Gene<sup>1</sup></td><td>Gene product<sup>2</sup></td><td>Reference</td></tr><tr><td colspan="3"><underline><i>A: Containing a TTA codon</i></underline></td></tr><tr><td>SCO4262</td><td>Hypothetical protein</td><td>[55]</td></tr><tr><td>SCO6638</td><td>Hypothetical protein</td><td>[55]</td></tr><tr><td colspan="3"><underline><i>B: Regulated by a TTA-containing gene</i></underline></td></tr><tr><td colspan="3"><underline>By <i>adpA</i></underline></td></tr><tr><td>SCO0762</td><td>Protease inhibitor</td><td>[55]</td></tr><tr><td><underline>By <i>SCO4263</i></underline></td><td></td><td></td></tr><tr><td>SCO4246</td><td>Hypothetical protein</td><td>[55]</td></tr><tr><td>SCO4251</td><td>Putative secreted protein</td><td>This study</td></tr><tr><td>SCO4252</td><td>Hypothetical protein</td><td>This study</td></tr><tr><td>SCO4253</td><td>Conserved hypothetical protein</td><td>This study</td></tr><tr><td><underline>By <i>act </i>II-ORF4</underline></td><td></td><td></td></tr><tr><td>SCO5071</td><td>Hydroxylacyl-CoA dehydrogenase, ActVI-ORFA</td><td>[14]</td></tr><tr><td>SCO5073</td><td>Putative oxidoreductase, ActVI-ORF2</td><td>[14]</td></tr><tr><td>SCO5074</td><td>Putative dehydratase, ActVI-ORF3</td><td>[14]</td></tr><tr><td>SCO5075</td><td>Putative oxidoreductase, ActVI-ORF4</td><td>[14]</td></tr><tr><td>SCO5078</td><td>Hypothetical protein</td><td>[14]</td></tr><tr><td>SCO5079</td><td>Conserved hypothetical protein</td><td>[14]</td></tr><tr><td>SCO5086</td><td>Ketoacyl reductase, ActIII</td><td>[14]</td></tr><tr><td>SCO5088</td><td>Polyketide beta-ketoacyl synthase, ActI-ORF2</td><td>[14]</td></tr><tr><td>SCO5090</td><td>Actinorhodin polyketide cyclase/dehdratase, ActVII</td><td>[14]</td></tr><tr><td><underline>By <i>redZ</i></underline></td><td></td><td></td></tr><tr><td>SCO5895</td><td>Putative methyltransferase, RedI</td><td>[20]</td></tr><tr><td colspan="3"><underline><i>C: In a putative operon with a TTA-containing gene</i></underline></td></tr><tr><td>SCO0392</td><td>Putative methyltransferase</td><td>[31]</td></tr><tr><td>SCO0395</td><td>Putative epimerase/dehydratase</td><td>[31]</td></tr><tr><td>SCO0400</td><td>Putative epimerase</td><td>[31]</td></tr><tr><td>SCO0401</td><td>Putative aminotransferase</td><td>[31]</td></tr><tr><td>SCO0991</td><td>Conserved hypothetical protein</td><td>[31]</td></tr><tr><td>SCO0994</td><td>Integral membrane protein</td><td>[31]</td></tr><tr><td>SCO0995</td><td>Probable methyltransferase</td><td>[31]</td></tr><tr><td>SCO6637</td><td>Hypothetical protein</td><td>[31]</td></tr></table> |
48e23524a4484d61cd756651603bdda92d50904f7308a8c6778ac6f94cccec98.png | complex | <table><tr><td>Domain</td><td>Question</td><td>Key process probed</td><td>Significance</td></tr><tr><td rowspan="2">Background</td><td>Previous occupation?</td><td>Previous cognitive/auditory function, noise exposure</td><td>Correct interpretation of hearing tests</td></tr><tr><td>Previous level of musical training and interest, early language development and education?</td><td>Prior auditory expertise</td><td>Correct interpretation of hearing tests</td></tr><tr><td rowspan="2">Course</td><td>When was hearing impairment first noticed?</td><td>Duration of impairment (relative to cognitive decline)</td><td>Nature of underlying disease process</td></tr><tr><td>Has this deteriorated, fluctuated or improved since onset?</td><td>Tempo of impairment</td><td>Nature of underlying disease process</td></tr><tr><td colspan="4">Symptoms</td></tr><tr><td rowspan="3"> Sound detection</td><td>Is there a lack of reaction to sounds?</td><td>Impaired sound detection</td><td>May signify deafness (any cause)</td></tr><tr><td>Is there a tendency to turn up the volume of radio or TV or to ask people to speak louder?</td><td>Impaired sound detection</td><td>May signify deafness (any cause)</td></tr><tr><td>Is there a complaint that increasing volume makes sounds suddenly seem too loud?</td><td>Impaired sound detection</td><td>May signify cochlear pathology (‘loudness recruitment’)</td></tr><tr><td rowspan="6"> Abnormal auditory perception: deficient</td><td>Is there particular difficulty following conversations in background noise or over a noisy telephone line?</td><td>Auditory scene analysis</td><td>May signify a cerebral disorder (e.g., Alzheimer’s disease) in absence of significant hearing loss</td></tr><tr><td>Is there difficulty locating sounds (e.g., an alarm or mobile, a person speaking in same the room)?</td><td>Auditory scene analysis</td><td>May signify a cerebral disorder in absence of significant hearing loss</td></tr><tr><td>Is there particular difficulty understanding speech versus other sounds?</td><td>Feature analysis</td><td>May signify word deafness</td></tr><tr><td>Is there more difficulty understanding less familiar accents?</td><td>Apperceptive processing</td><td>May signify a cerebral disorder in absence of significant hearing loss</td></tr><tr><td>Is there more difficulty understanding a person’s tone of voice (e.g., angry or upset)?</td><td>Apperceptive and emotional processing</td><td>May signify a frontotemporal dementia in appropriate context</td></tr><tr><td>Has there been any problem recognising familiar voices, music or other sounds?</td><td>Semantic processing</td><td>May signify auditory agnosia or semantic dementia, in appropriate context</td></tr><tr><td rowspan="2"> Abnormal auditory perception: excessive</td><td>Is there a persistent complaint of buzzing or ringing in the ears?</td><td>Tinnitus</td><td>May be peripheral or central in origin</td></tr><tr><td>Are other sounds ever heard when no sounds are present?</td><td>Formed hallucinations</td><td>May signify Lewy body disease, in appropriate context</td></tr><tr><td rowspan="2"> Abnormal auditory behaviour</td><td>Is there intolerance to moderately loud sounds or particular sounds?</td><td>Hyperacusis</td><td>May signify a frontotemporal dementia in appropriate context</td></tr><tr><td>Has there been any change in liking for or interest in music or other sounds?</td><td>Auditory hedonic processing</td><td>May signify a frontotemporal dementia in appropriate context</td></tr></table> |
ba76932ac4ad64a2fd5dbf3637d7d80215e65fa792dfe490d6a6044f15bc6e9b.png | complex | <table><tr><td rowspan="2">Level of education</td><td rowspan="2">Specialization/means of accessing information</td><td rowspan="2"><i>n</i></td><td>Heard about aflatoxins</td></tr><tr><td>Frequency (% of <i>n</i>)</td></tr><tr><td> </td><td><i>Specialization</i></td><td> </td><td> </td></tr><tr><td rowspan="2">Low</td><td>Life/social sciences</td><td>0</td><td>0 (0)</td></tr><tr><td>None/other fields</td><td>110</td><td>12 (11)</td></tr><tr><td rowspan="2">High</td><td>Life/social sciences</td><td>132</td><td>55 (42)</td></tr><tr><td>None/other fields</td><td>16</td><td>4 (25)</td></tr><tr><td colspan="2">Total</td><td>258</td><td>71 (28)</td></tr><tr><td> </td><td><i>Means of accessing information</i></td><td> </td><td> </td></tr><tr><td rowspan="4">Low</td><td>Reading</td><td>3</td><td>1 (33)</td></tr><tr><td>Mass media (radio/TV)</td><td>69</td><td>6 (9)</td></tr><tr><td>Seminars/experts</td><td>11</td><td>1 (9)</td></tr><tr><td>Friends/neighbours</td><td>8</td><td>3 (37)</td></tr><tr><td rowspan="4">High</td><td>Reading</td><td>3</td><td>2 (67)</td></tr><tr><td>Mass media (radio/TV)</td><td>69</td><td>43 (91)</td></tr><tr><td>Seminars/experts</td><td>11</td><td>10 (91)</td></tr><tr><td>Friends/neighbours</td><td>8</td><td>5 (63)</td></tr></table> |
a604a5d79b209a33384ec497c4bdb9c6cc2a48f12e5a21e13733a4004f529746.png | simple | <table><tr><td>Biological process</td><td></td><td>Number of genes affected by FOS*</td></tr><tr><td><i>Mitochondria</i></td><td>Complex I</td><td>27</td></tr><tr><td></td><td>Complex II</td><td>5</td></tr><tr><td></td><td>Complex III</td><td>2</td></tr><tr><td></td><td>Complex IV</td><td>13</td></tr><tr><td></td><td>Complex V</td><td>21</td></tr><tr><td></td><td>Metabolism and TCA cycle</td><td>53</td></tr><tr><td></td><td>Mitochondrial ribosomes</td><td>33</td></tr><tr><td></td><td>Protein transport</td><td>11</td></tr><tr><td></td><td>Miscellaneous</td><td>12</td></tr><tr><td><i>Protein turnover</i></td><td>Protein degradation</td><td>31</td></tr><tr><td></td><td>Translation</td><td>44</td></tr><tr><td></td><td>Protein maturation</td><td>32</td></tr><tr><td></td><td>Miscellaneous</td><td>6</td></tr><tr><td><i>Transcription</i></td><td>Chromatin related</td><td>22</td></tr><tr><td></td><td>mRNA metabolism</td><td>7</td></tr><tr><td></td><td>Transcription</td><td>26</td></tr><tr><td></td><td>Miscellaneous</td><td>6</td></tr><tr><td><i>Cell turnover</i></td><td>Apoptosis</td><td>19</td></tr><tr><td></td><td>Growth/Differentiation</td><td>16</td></tr><tr><td><i>Mucosal barrier</i></td><td></td><td>30</td></tr><tr><td><i>Cytoskeleton</i></td><td></td><td>26</td></tr><tr><td><i>Transport</i></td><td></td><td>20</td></tr><tr><td><i>Oxidative stress</i></td><td></td><td>16</td></tr><tr><td><i>Vesicle related</i></td><td></td><td>10</td></tr><tr><td><i>Peptide hormones</i></td><td></td><td>6</td></tr><tr><td><i>Other†</i></td><td></td><td>503</td></tr><tr><td></td><td></td><td>997</td></tr></table> |
bad1452dc31fb1fa8f05be625eaab848ba4e1b608a09d4d76688f744535226e2.png | simple | <table><tr><td>Beat type</td><td>Number of beats in Test data set</td><td>Number of beats in Training data set</td><td>Possession rate (%)</td></tr><tr><td>Normal</td><td>54516</td><td>5000</td><td>70.2573</td></tr><tr><td>LBBB</td><td>6036</td><td>1000</td><td>7.7746</td></tr><tr><td>RBBB</td><td>5410</td><td>1000</td><td>6.9889</td></tr><tr><td>PVC</td><td>5293</td><td>1000</td><td>6.8166</td></tr><tr><td>APB</td><td>1896</td><td>1000</td><td>2.4407</td></tr><tr><td>PB</td><td>2702</td><td>1000</td><td>3.4853</td></tr><tr><td>Total</td><td>75853</td><td>10000</td><td>97.76</td></tr></table> |
d8ba7e212b1ef408fd5eed815ce6866bcf50bc907e4e616b27b093145a7db640.png | complex | <table><tr><td></td><td colspan="9">Input Text Symbol</td></tr><tr><td>Current State</td><td>A</td><td>B</td><td>C</td><td>D</td><td>E</td><td>F</td><td>...</td><td>Z</td><td>Match</td></tr><tr><td>0</td><td>1</td><td>0</td><td>7</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Ø</td></tr><tr><td>1</td><td>1</td><td>0</td><td>2</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Ø</td></tr><tr><td>2</td><td>3</td><td>0</td><td>7</td><td>0</td><td>6</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Ø</td></tr><tr><td>3</td><td>1</td><td>0</td><td>4</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Ø</td></tr><tr><td>4</td><td>3</td><td>0</td><td>7</td><td>5</td><td>6</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Pep2</td></tr><tr><td>5</td><td>1</td><td>0</td><td>7</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Pep1</td></tr><tr><td>6</td><td>1</td><td>0</td><td>7</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Pep3</td></tr><tr><td>7</td><td>8</td><td>0</td><td>7</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Ø</td></tr><tr><td>8</td><td>1</td><td>0</td><td>9</td><td>0</td><td>0</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Ø</td></tr><tr><td>9</td><td>3</td><td>0</td><td>7</td><td>0</td><td>6</td><td>0</td><td>0,0,...,0</td><td>0</td><td>Pep2</td></tr></table> |
562bec6e1602bdd3614addbb7e6da38a24f2094e235e0bc69878411eaaac7380.png | complex | <table><tr><td rowspan="2">Patient characteristics</td><td colspan="2">NNStotal</td><td colspan="2">NNS carb.beverages</td><td colspan="2">NNS non-carb.beverages</td><td colspan="2">NNSsweeteners</td></tr><tr><td>B</td><td><i>p</i>-value</td><td>B</td><td><i>p</i>-value</td><td>B</td><td><i>p</i>-value</td><td>B</td><td><i>p</i>-value</td></tr><tr><td>Gender (female/male)</td><td>−0.10</td><td>0.838</td><td>0.519</td><td>0.285</td><td>−0.049</td><td>0.924</td><td>−2.896</td><td>0.005</td></tr><tr><td>Age (years)</td><td>−0.04</td><td>0.073</td><td>−0.014</td><td>0.544</td><td>−0.045</td><td>0.063</td><td>0.002</td><td>0.951</td></tr><tr><td>BMI (kg/m2)</td><td>−0.025</td><td>0.640</td><td>−0.007</td><td>0.902</td><td>−0.032</td><td>0.582</td><td>0.040</td><td>0.510</td></tr><tr><td>Living with someone</td><td>−0.728</td><td>0.151</td><td>−0.030</td><td>0.953</td><td>−0.981</td><td>0.060</td><td>−0.011</td><td>0.985</td></tr><tr><td>Working</td><td>−0.124</td><td>0.594</td><td>0.383</td><td>0.114</td><td>−0.379</td><td>0.126</td><td>−0.047</td><td>0.858</td></tr><tr><td>Smoking</td><td>0.194</td><td>0.485</td><td>0.196</td><td>0.492</td><td>−0.043</td><td>0.884</td><td>−0.110</td><td>0.715</td></tr><tr><td>Perceived general health</td><td>0.011</td><td>0.965</td><td>0.070</td><td>0.793</td><td>0.098</td><td>0.722</td><td>0.083</td><td>0.771</td></tr><tr><td>Total physical activity</td><td>−0.184</td><td>0.029</td><td>−0.086</td><td>0.308</td><td>−0.030</td><td>0.732</td><td>0.014</td><td>0.883</td></tr><tr><td>Heavy physical activity</td><td>−0.477</td><td>0.011</td><td>−0.368</td><td>0.052</td><td>−0.212</td><td>0.278</td><td>0.116</td><td>0.576</td></tr><tr><td>Hypertension</td><td>0.201</td><td>0.607</td><td>0.261</td><td>0.518</td><td>−0.128</td><td>0.759</td><td>−0.340</td><td>0.442</td></tr><tr><td>Diabetes</td><td>0.971</td><td>0.039</td><td>0.639</td><td>0.174</td><td>1.227</td><td>0.012</td><td>0.171</td><td>0.748</td></tr><tr><td>Fibromyalgia</td><td>0.696</td><td>0.131</td><td>0.202</td><td>0.664</td><td>0.718</td><td>0.132</td><td>0.568</td><td>0.249</td></tr><tr><td>Muscle-skeletal pain score (range 0-12)</td><td>−0.004</td><td>0.952</td><td>0.001</td><td>0.987</td><td>−0.097</td><td>0.149</td><td>0.058</td><td>0.397</td></tr><tr><td>HSCL10 > 1.85</td><td>0.073</td><td>0.855</td><td>−0.194</td><td>0.639</td><td>−0.664</td><td>0.137</td><td>−0.028</td><td>0.951</td></tr><tr><td>WHO-5 (poor wellbeing)</td><td>0.452</td><td>0.249</td><td>0.805</td><td>0.046</td><td>−0.135</td><td>0.746</td><td>−0.297</td><td>0.509</td></tr><tr><td>Fatigue</td><td>1.232</td><td>0.001</td><td>0.490</td><td>0.184</td><td>0.316</td><td>0.408</td><td>0.575</td><td>0.159</td></tr><tr><td>IBS</td><td>0.317</td><td>0.444</td><td>−0.193</td><td>0.651</td><td>0.207</td><td>0.633</td><td>−0.047</td><td>0.915</td></tr><tr><td>Functional bloating</td><td>−0.379</td><td>0.486</td><td>0.600</td><td>0.280</td><td>−0.714</td><td>0.258</td><td>−1.365</td><td>0.067</td></tr><tr><td>Functional diarrhea</td><td>NA</td><td>NA</td><td>NA</td><td>NA</td><td>NA</td><td>NA</td><td>NA</td><td>NA</td></tr><tr><td>GSRS-diarrhea (score)</td><td>0.625</td><td>0.009</td><td>0.178</td><td>0.447</td><td>0.176</td><td>0.467</td><td>0.626</td><td>0.012</td></tr><tr><td>GSRS-bloating (score)</td><td>−0.112</td><td>0.509</td><td>−0.033</td><td>0.849</td><td>−0.324</td><td>0.084</td><td>−0.184</td><td>0.320</td></tr><tr><td colspan="9">Blood tests</td></tr><tr><td> Haemoglobin (g/dl)</td><td>−0.299</td><td>0.149</td><td>−0.063</td><td>0.765</td><td>−0.625</td><td>0.007</td><td>−0.534</td><td>0.022</td></tr><tr><td> Serum iron (μmol/L</td><td>−0.015</td><td>0.648</td><td>−0.042</td><td>0.237</td><td>−0.011</td><td>0.768</td><td>−0.049</td><td>0.205</td></tr><tr><td> Transferrin saturation</td><td>−0.875</td><td>0.673</td><td>−0.025</td><td>0.255</td><td>−0.011</td><td>0.631</td><td>−0.033</td><td>0.167</td></tr><tr><td> Ferritin (μg/dL)</td><td>0.002</td><td>0.311</td><td>−0.001</td><td>0.450</td><td>0.000</td><td>0.909</td><td>−0.001</td><td>0.615</td></tr><tr><td> CRP (mg/L)</td><td>0.040</td><td>0.226</td><td>0.029</td><td>0.393</td><td>0.081</td><td>0.020</td><td>0.042</td><td>0.228</td></tr><tr><td> s-Glucose (mmol/L)</td><td>0.110</td><td>0.082</td><td>0.122</td><td>0.055</td><td>0.044</td><td>0.492</td><td>0.005</td><td>0.944</td></tr><tr><td> HbA1C (%)</td><td>0.294</td><td>0.052</td><td>0.235</td><td>0.117</td><td>0.367</td><td>0.018</td><td>0.076</td><td>0.644</td></tr><tr><td> c-peptide (nmol/L)</td><td>0.662</td><td>0.005</td><td>0.410</td><td>0.077</td><td>0.279</td><td>0.244</td><td>0.509</td><td>0.052</td></tr><tr><td> Cholesterol (mmol/L)</td><td>0.116</td><td>0.542</td><td>0.188</td><td>0.339</td><td>−0.043</td><td>0.830</td><td>−0.096</td><td>0.661</td></tr><tr><td> HDL (mmol/L)</td><td>−0.612</td><td>0.291</td><td>−0.164</td><td>0.782</td><td>−1.017</td><td>0.115</td><td>0.541</td><td>0.394</td></tr><tr><td> LDL (mmol/L)</td><td>0.164</td><td>0.427</td><td>0.164</td><td>0.438</td><td>−0.026</td><td>0.907</td><td>−0.179</td><td>0.457</td></tr><tr><td> Vitamin A (μmol/L)</td><td>0.291</td><td>0.536</td><td>−0.725</td><td>0.136</td><td>−0.232</td><td>0.644</td><td>0.050</td><td>0.921</td></tr><tr><td> Vitamin B1 (nmol/L)</td><td>0.008</td><td>0.243</td><td>0.006</td><td>0.356</td><td>0.001</td><td>0.876</td><td>0.007</td><td>0.363</td></tr><tr><td> Vitamin B6 (nmol/L)</td><td>0.004</td><td>0.479</td><td>0.005</td><td>0.407</td><td>−0.011</td><td>0.178</td><td>−0.002</td><td>0.759</td></tr><tr><td> Vitamin B12 (pmol/L)</td><td>−0.001</td><td>0.384</td><td>0.000</td><td>0.727</td><td>0.000</td><td>0.940</td><td>−0.001</td><td>0.503</td></tr><tr><td> Vitamin D (nmol/L)</td><td>0.006</td><td>0.458</td><td>0.012</td><td>0.166</td><td>0.001</td><td>0.952</td><td>0.000</td><td>0.966</td></tr><tr><td> Folic acid (nmol/L)</td><td>−0.024</td><td>0.269</td><td>−0.007</td><td>0.759</td><td>−0.021</td><td>0.362</td><td>−0.018</td><td>0.433</td></tr></table> |
c5437ab8b1c6cc2333c4ecdd89b8e9f7d4b4344a38fa1c4039dc76146c11c1a9.png | complex | <table><tr><td> </td><td> </td><td colspan="4"> <i>Attentional bias index to fearful expression</i> </td></tr><tr><td> </td><td> </td><td> <i>12 months</i> </td><td> <i>18 months</i> </td><td> <i>24 months</i> </td><td> <i>36 months</i> </td></tr><tr><td>Fear scale (IBQ-R or ECBQ)</td><td>12 months</td><td>−.020</td><td>-</td><td>-</td><td>-</td></tr><tr><td> </td><td>18 months</td><td>.240</td><td>−.231</td><td>-</td><td>-</td></tr><tr><td> </td><td>24 months</td><td>−.100</td><td>−.335</td><td>−.262</td><td>-</td></tr><tr><td> </td><td>36 months</td><td>.174</td><td>−.463</td><td>.105</td><td>.017</td></tr><tr><td>Average score of scales loading on Negative Affect</td><td>12 months</td><td>.527**</td><td>-</td><td>-</td><td>-</td></tr><tr><td> </td><td>18 months</td><td>.403</td><td>−.083</td><td>-</td><td>-</td></tr><tr><td> </td><td>24 months</td><td>.222</td><td>−.286</td><td>−.023</td><td>-</td></tr><tr><td> </td><td>36 months</td><td>.309</td><td>−.276</td><td>−.125</td><td>.146</td></tr></table> |
bb2cbec9f890a58f97fd5167890be8d62b80f7a8e7f9b28cd6c968b4c74e717e.png | simple | <table><tr><td></td><td>Pearls</td><td>Cheese matrix</td></tr><tr><td>Total solids (%)</td><td>79.09</td><td>70.37</td></tr><tr><td>Fat (%)</td><td>28</td><td>32</td></tr><tr><td>FDM (%)</td><td>35.4</td><td>45.5</td></tr><tr><td>Free leucine (%)</td><td>1.0</td><td>–</td></tr></table> |
2e6c62a5b70d6b6515b98ef8dac3dffa1421f8b3482b5f455ed7cc3a30427622.png | simple | <table><tr><td>Gait speed change DT</td><td><i>P</i></td><td>Stand. β</td><td><i>R</i><sup>2</sup></td><td>95% CI</td></tr><tr><td>SAI mean</td><td><0.001</td><td>−0.46</td><td>0.22</td><td>[−39.0, −13.7]</td></tr><tr><td>Adjusted for age</td><td><0.001</td><td>−0.47</td><td>0.23</td><td>[−39.6, −14.3]</td></tr><tr><td>Adjusted for age, MoCA</td><td>0.015</td><td>−0.34</td><td>0.27</td><td>[−34.8, −3.9]</td></tr></table> |
359b059ec95f47fcce3ab60065428822fc75760d7a3ac4b3b78e18db3a77fe0d.png | complex | <table><tr><td rowspan="2">Stud #</td><td rowspan="2">Institution</td><td colspan="2">Parents</td><td colspan="3">Habitat</td></tr><tr><td>Stud #</td><td>Sex</td><td>XXL</td><td>MIN</td><td>QIO</td></tr><tr><td>358</td><td>WOLONG</td><td>Wild</td><td>-</td><td>0</td><td>0</td><td>1.0</td></tr><tr><td rowspan="2">425</td><td rowspan="2">CHENGDU</td><td>298</td><td>M</td><td>0</td><td>1.0</td><td>0</td></tr><tr><td>314</td><td>F</td><td>0.5</td><td>0</td><td>0.5</td></tr><tr><td rowspan="2">557</td><td rowspan="2">WOLONG</td><td>399</td><td>M</td><td>0</td><td>0</td><td>1.0</td></tr><tr><td>446</td><td>F</td><td>0</td><td>1.0</td><td>0</td></tr></table> |
8cdae4e4fad02355b879901beb1f533a1ec83b886ca74f6a0cf7e8e3be4f5363.png | complex | <table><tr><td rowspan="2">Variables</td><td>Number of participants</td><td>Candidiasis</td><td>Bacterial vaginosis</td><td>Trichomoniasis</td></tr><tr><td>N (%)</td><td>N (%)</td><td>N (%)</td><td>N (%)</td></tr><tr><td>Age of participants</td><td></td><td></td><td></td><td></td></tr><tr><td><20</td><td>31 (7.6)</td><td>1 (3.2)</td><td>1 (3.2)</td><td>0</td></tr><tr><td>20–29</td><td>218 (53.3)</td><td>16 (7.3)</td><td>5 (2.3)</td><td>5 (2.3)</td></tr><tr><td>30–39</td><td>107 (26.2)</td><td>14 (13.1)</td><td>1 (0.9)</td><td>2 (1.9)</td></tr><tr><td>40–49</td><td>53 (12.9)</td><td>3 (5.6)</td><td>5 (9.4)***</td><td>1(1.9)</td></tr><tr><td>Marital status</td><td></td><td></td><td></td><td></td></tr><tr><td>Single</td><td>54 (13.2)</td><td>2 (3.7)</td><td>2 (3.7)</td><td>0</td></tr><tr><td>Married</td><td>312 (76.3)</td><td>30 (9.6)</td><td>9 (2.9)</td><td>8 (25)</td></tr><tr><td>Divorced</td><td>43 (10.5)</td><td>2 (4.7)</td><td>1 (2.3)</td><td>0</td></tr><tr><td>Residence</td><td></td><td></td><td></td><td></td></tr><tr><td>Rural</td><td>116 (28.4)</td><td>8 (6.9)</td><td>7 (10.3)***</td><td>4 (3.4)</td></tr><tr><td>Urban</td><td>293 (71.6)</td><td>26 (8.9)*</td><td>5 (1.7)</td><td>4 (1.4)</td></tr><tr><td>Religion</td><td></td><td></td><td></td><td></td></tr><tr><td>Orthodox</td><td>368 (90)</td><td>27 (7.3)</td><td>12 (2.7)</td><td>6 (1.6)</td></tr><tr><td>Other</td><td>41 (10)</td><td>7 (17.1)***</td><td>0</td><td>2 (0.5)</td></tr><tr><td>Educational status</td><td></td><td></td><td></td><td></td></tr><tr><td>College and above</td><td>121 (29.6)</td><td>13 (10.7)</td><td>1 (0.8)</td><td>0</td></tr><tr><td>Highs school</td><td>70 (17.1)</td><td>9 (12.9)</td><td>1 (1.4)</td><td>3 (4.3)</td></tr><tr><td>Elementary</td><td>41 (10)</td><td>1 (2.4)</td><td>2 (4.9)</td><td>0</td></tr><tr><td>Read and write</td><td>39 (9.5)</td><td>4 (10.3)</td><td>2 (5.1)</td><td>0</td></tr><tr><td>Illiterate</td><td>138 (33.7)</td><td>7 (5.1)</td><td>6 (4.3)</td><td>5 (3.6)</td></tr><tr><td>Occupational status</td><td></td><td></td><td></td><td></td></tr><tr><td>Employed</td><td>131 (32)</td><td>15 (11.5)</td><td>1 (0.8)***</td><td>1 (0.8)</td></tr><tr><td>Farmer</td><td>104 (25.4)</td><td>9 (8.7)</td><td>8 (7.7)</td><td>3 (2.9)</td></tr><tr><td>Merchant</td><td>28 (6.9)</td><td>5 (17.9)***</td><td>0</td><td>1 (3.6)</td></tr><tr><td>Students</td><td>44 (10.8)</td><td>3 (6.8)</td><td>2 (4.5)</td><td>1 (2.3)</td></tr><tr><td>Unemployed</td><td>101 (24.8)</td><td>2 (2)</td><td>1 (1)</td><td>2 (2)</td></tr><tr><td>Total</td><td>409 (100)</td><td>34 (8.2)</td><td>12 (2.9)</td><td>8 (2)</td></tr></table> |
034bc614837d92fc89605ea37dcf71ab7ccba54d59b96120511b91cb0293ba3a.png | simple | <table><tr><td>Name</td><td>Sequences (5'-3')</td><td>Description</td></tr><tr><td>OP-F</td><td>TCTGGAATGGCTGAAGAAGACG</td><td>Forward primer for the actin gene of <i>T. vaginalis</i> in the first stage</td></tr><tr><td>OP-R</td><td>CAGGGTACATCGTATTGGTC</td><td>Reverse primer for the actin gene of <i>T. vaginalis</i> in the first stage</td></tr><tr><td>IP-F</td><td>CAGACACTCGTTATCG</td><td>Forward primer for the actin gene of <i>T. vaginalis</i> in the second stage</td></tr><tr><td>IP-R</td><td>CGGTGAACGATGGATG</td><td>Reverse primer for the actin gene of <i>T. vaginalis</i> in the second stage</td></tr></table> |
cd7ed7dd9690925f0e7cc22100af7ddf29336e247de5b92f04a6ec8f6dfd7cad.png | simple | <table><tr><td>Drugs</td><td>Direct Inhibition of HERG K<sup>+</sup> Channel</td><td>Inhibition of HERG K<sup>+</sup> Channel Trafficking</td></tr><tr><td>Phenothiazines</td><td>+</td><td>?</td></tr><tr><td>Pentamidine</td><td>-</td><td>+</td></tr><tr><td>Geldalamicin</td><td>-</td><td>+</td></tr><tr><td>Arsenic Trioxide</td><td>-</td><td>+</td></tr><tr><td>Fluoxetine, Norfluoxetine</td><td>+</td><td>+</td></tr><tr><td>Ketoconazole</td><td>+</td><td>+</td></tr><tr><td>Digitoxin, Ouabain, Digoxin</td><td>-</td><td>+</td></tr><tr><td>Sparfluoxacin, Ciprofloxacin, Ofloxacin</td><td>+</td><td>-</td></tr><tr><td>Amsacrin</td><td>+</td><td>-</td></tr><tr><td>Probucol</td><td>-</td><td>+</td></tr><tr><td>Cisapride</td><td>+</td><td></td></tr></table> |
35c4fc5ee56fd9a45688b7be2d21c1ec81e9e0735fa655f66ca6fcd5efbe14fe.png | complex | <table><tr><td rowspan="3">Characteristic</td><td colspan="4">Total nut intake (g/day)</td><td colspan="3">Peanut butter intake (g/day)</td></tr><tr><td>0 g/day</td><td>0.1–< 5</td><td>5–< 10</td><td>10 +g/day</td><td>0 g/day</td><td>0.1–< 5</td><td>5 + g/day</td></tr><tr><td>(<i>n</i> = 821)</td><td>(<i>n</i> = 735)</td><td>(<i>n</i> = 225)</td><td>(<i>n</i> = 246)</td><td>(<i>n</i> = 1493)</td><td>(<i>n</i> = 351)</td><td>(<i>n</i> = 183)</td></tr><tr><td>Age (years)</td><td>62.2 (4.4)</td><td>61.1 (4.2)</td><td>60.1 (4.0)</td><td>60.6 (3.9)</td><td>61.6 (4.3)</td><td>60.9 (4.0)</td><td>60.7 (4.0)</td></tr><tr><td>Height (cm)</td><td>164.9 (6.5)</td><td>165.5 (5.8)</td><td>165.6 (6.0)</td><td>165.8 (6.2)</td><td>165.4 (6.1)</td><td>165.1 (6.0)</td><td>165.2 (6.6)</td></tr><tr><td>BMI (kg/m<sup>2</sup>)</td><td>25.3 (3.8)</td><td>25.1 (3.4)</td><td>24.4 (3.1)</td><td>24.5 (3.3)</td><td>25.0 (3.6)</td><td>25.2 (3.4)</td><td>24.4 (3.2)</td></tr><tr><td>Physical activity (min/day)</td><td>62.9 (55.2)</td><td>65.8 (48.1)</td><td>71.7 (55.1)</td><td>60.8 (37.4)</td><td>62.3 (48.4)</td><td>72.8 (60.0)</td><td>68.3 (49.2)</td></tr><tr><td>Age at menarche (years)</td><td>13.7 (1.8)</td><td>13.6 (1.7)</td><td>13.7 (1.8)</td><td>13.6 (1.7)</td><td>13.6 (1.7)</td><td>13.7 (1.9)</td><td>13.8 (1.9)</td></tr><tr><td>Age at menopause (years)</td><td>48.7 (4.4)</td><td>48.7 (4.6)</td><td>49 (4.4)</td><td>48.9 (4.3)</td><td>48.7 (4.5)</td><td>48.6 (4.4)</td><td>49.6 (4.2)</td></tr><tr><td>Alcohol intake (g/day)</td><td>4.9 (9.5)</td><td>5.8 (8.8)</td><td>7.2 (9.3)</td><td>8.6 (10.9)</td><td>6.1 (9.7)</td><td>5.5 (9.1)</td><td>4.9 (7.9)</td></tr><tr><td>Peanut butter intake (g/day)</td><td>1.0 (3.5)</td><td>1.2 (3.7)</td><td>1.3 (3.5)</td><td>1.3 (3.3)</td><td></td><td></td><td></td></tr><tr><td>Total nut intake (g/day)</td><td></td><td></td><td></td><td></td><td>4.1 (8.3)</td><td>5.2 (8.7)</td><td>4.9 (8.5)</td></tr><tr><td>Never smoker (%)</td><td>60.7</td><td>59.3</td><td>49.8</td><td>50.4</td><td>57.9</td><td>54.7</td><td>62.3</td></tr><tr><td>University or higher vocational education (%)</td><td>6.2</td><td>10.7</td><td>14.3</td><td>12.6</td><td>8.4</td><td>11.5</td><td>14.8</td></tr><tr><td>Nulliparous (%)</td><td>17.7</td><td>20.5</td><td>16.9</td><td>17.6</td><td>18.1</td><td>19.0</td><td>22.0</td></tr><tr><td>Age at first birth ≥ 30 years (% of parous)</td><td>22.8</td><td>19.5</td><td>26.6</td><td>26.7</td><td>22.4</td><td>21.3</td><td>25.9</td></tr><tr><td>Ever used oral contraceptives (%)</td><td>20.6</td><td>24.9</td><td>35.6</td><td>33.2</td><td>24.3</td><td>27.8</td><td>29.5</td></tr><tr><td>Ever used hormone replacement therapy (%)</td><td>12.2</td><td>13.8</td><td>13.3</td><td>16.4</td><td>13.8</td><td>13.5</td><td>9.7</td></tr><tr><td>Family history breast cancer (%)</td><td>8.4</td><td>10.2</td><td>6.7</td><td>7.7</td><td>9.1</td><td>9.1</td><td>5.5</td></tr><tr><td>History benign breast disease (%)</td><td>6.8</td><td>9.4</td><td>8.4</td><td>6.5</td><td>8.5</td><td>6.3</td><td>6.0</td></tr><tr><td>aMEDr<sup>a</sup> score (excluding nuts) 5–7 pts (%)</td><td>20.5</td><td>27.3</td><td>26.7</td><td>32.1</td><td>23.4</td><td>27.9</td><td>33.3</td></tr></table> |
47a6e301edf395b8d31b72a42ce6cc4d14631d44b0f2c33096684fc83419af2a.png | simple | <table><tr><td>Variant</td><td><i>p-</i>value<sup>a</sup></td><td>Annotation</td></tr><tr><td>rs1800361</td><td>3.01E-04</td><td>nonsynonymous</td></tr><tr><td>rs145497019</td><td>1.20E-05</td><td>nonsynonymous</td></tr><tr><td>rs1800362</td><td>9.71E-06</td><td>nonsynonymous</td></tr><tr><td>rs1800368</td><td>9.71E-06</td><td>nonsynonymous</td></tr><tr><td>rs138629441</td><td>5.79E-06</td><td>nonsynonymous</td></tr><tr><td>rs143152201</td><td>3.19E-06</td><td>nonsynonymous</td></tr><tr><td>9:97869388</td><td>2.33E-06</td><td>nonsynonymous</td></tr><tr><td><i>FANCC</i></td><td>2.27E-06<sup>b</sup></td><td></td></tr><tr><td>9:97887391</td><td>2.27E-06</td><td>nonsynonymous</td></tr><tr><td>rs1800367</td><td>2.27E-06</td><td>nonsynonymous</td></tr><tr><td>9:97876956</td><td>2.20E-06</td><td>nonsynonymous</td></tr><tr><td>rs140687953</td><td>1.87E-06</td><td>nonsynonymous</td></tr><tr><td>rs140781259</td><td>1.70E-06</td><td>nonsynonymous</td></tr><tr><td>9:97934335</td><td>1.66E-06</td><td>nonsynonymous</td></tr><tr><td>rs1800366</td><td>1.65E-06</td><td>nonsynonymous</td></tr><tr><td>rs121917783</td><td>1.59E-06</td><td>stop-gain</td></tr><tr><td>rs1800365</td><td>1.48E-06</td><td>nonsynonymous</td></tr></table> |
bab6b8a0d457a3f626370fecd81f210e5f009b48944d4827ea15d352da9c0c5c.png | simple | <table><tr><td> </td><td>Total</td><td>Blood</td><td>Urine</td><td>Abscess drainage</td><td>Other</td></tr><tr><td>Gram-positive<sup>a</sup></td><td>90</td><td>44</td><td>27</td><td>25</td><td>18</td></tr><tr><td><i>Streptococcus pneumonia</i></td><td>29</td><td>14</td><td>20<sup>b</sup></td><td>0</td><td>5</td></tr><tr><td><i>Alpha hemolytic streptococci</i></td><td>18</td><td>7</td><td>0</td><td>6</td><td>7</td></tr><tr><td><i>Group A/C/G streptococci</i></td><td>13</td><td>6</td><td>0</td><td>9</td><td>1</td></tr><tr><td><i>Group B streptococci</i></td><td>2</td><td>1</td><td>0</td><td>1</td><td>0</td></tr><tr><td><i>Enterococci</i></td><td>6</td><td>3</td><td>2</td><td>0</td><td>2</td></tr><tr><td><i>Staphylococcus aureus</i></td><td>20</td><td>11</td><td>4</td><td>9</td><td>3</td></tr><tr><td><i>Staphylococcus caprae</i></td><td>1</td><td>1</td><td>0</td><td>0</td><td>0</td></tr><tr><td><i>Aerococcus viridans</i></td><td>1</td><td>1</td><td>1</td><td>0</td><td>0</td></tr><tr><td>Gram-negative<sup>a</sup></td><td>55</td><td>32</td><td>21</td><td>8</td><td>9</td></tr><tr><td><i>Escherichia coli</i></td><td>27</td><td>19</td><td>13</td><td>3</td><td>3</td></tr><tr><td><i>Klebsiella</i></td><td>10</td><td>6</td><td>5</td><td>0</td><td>1</td></tr><tr><td><i>Enterobacter</i></td><td>1</td><td>1</td><td>0</td><td>0</td><td>0</td></tr><tr><td><i>Proteus</i></td><td>2</td><td>0</td><td>0</td><td>1</td><td>1</td></tr><tr><td><i>Other Enterobacteriaceae</i></td><td>5</td><td>2</td><td>3</td><td>1</td><td>0</td></tr><tr><td><i>Pseudomonas aeruginosa</i></td><td>2</td><td>1</td><td>0</td><td>1</td><td>1</td></tr><tr><td><i>Stenotrophomonas maltophilia</i></td><td>1</td><td>0</td><td>0</td><td>1</td><td>0</td></tr><tr><td><i>Neisseriae meningitides</i></td><td>2</td><td>2</td><td>0</td><td>0</td><td>0</td></tr><tr><td><i>Haemophilus influenzae</i></td><td>2</td><td>1</td><td>0</td><td>0</td><td>1</td></tr><tr><td><i>Haemophilus parainfluenzae</i></td><td>2</td><td>0</td><td>0</td><td>0</td><td>2</td></tr><tr><td><i>Unspecified gram negative rods</i></td><td>1</td><td>0</td><td>0</td><td>1</td><td>0</td></tr><tr><td>Anaerobic bacteria</td><td>17</td><td>6</td><td>0</td><td>3</td><td>9</td></tr><tr><td><i>Clostridium species</i></td><td>5</td><td>2</td><td>0</td><td>0</td><td>3<sup>c</sup></td></tr><tr><td><i>Bacteroides species</i></td><td>5</td><td>3</td><td>0</td><td>1</td><td>2</td></tr><tr><td><i>Prevotella</i></td><td>4</td><td>0</td><td>0</td><td>2</td><td>2</td></tr><tr><td><i>Slackia exigua</i></td><td>1</td><td>1</td><td>0</td><td>0</td><td>0</td></tr><tr><td><i>Fusobacterium</i></td><td>1</td><td>0</td><td>0</td><td>0</td><td>1</td></tr><tr><td><i>Unspecified gram positive rods</i></td><td>1</td><td>0</td><td>0</td><td>0</td><td>1</td></tr><tr><td>Other</td><td>9</td><td>0</td><td>0</td><td>3</td><td>6</td></tr><tr><td><i>Candida species</i></td><td>7</td><td>0</td><td>0</td><td>3</td><td>4</td></tr><tr><td><i>Aspergillus species</i></td><td>1</td><td>0</td><td>0</td><td>0</td><td>1</td></tr><tr><td><i>Influenzavirus A</i></td><td>1</td><td>0</td><td>0</td><td>0</td><td>1</td></tr><tr><td>Patients with ≥1 positive test</td><td>129</td><td>74</td><td>40</td><td>23</td><td>29</td></tr></table> |
0a9749968f72a22242a7f9ff43efcc22074214aefa01f61531ac9ab54a7732c7.png | simple | <table><tr><td>Grade of fibrosis</td><td>Histological changes</td></tr><tr><td>0</td><td>Normal lung</td></tr><tr><td>1</td><td>Minimal fibrous thickening of alveolar/bronchial walls</td></tr><tr><td>2</td><td><i>Intermediary stage between 1 and 3</i></td></tr><tr><td>3</td><td>Moderate thickening of walls without obvious damage to the lung architecture</td></tr><tr><td>4</td><td><i>Intermediary stage between 3 and 5</i></td></tr><tr><td>5</td><td>Increased fibrosis with definite damage to lung structure and formation of fibrous bands or small fibrous masses</td></tr><tr><td>6</td><td><i>Intermediary stage between 5 and 7</i></td></tr><tr><td>7</td><td>Severe distortion of structure and large fibrous areas; honeycombing lung is placed in this category</td></tr><tr><td>8</td><td>Total fibrous obliteration of the field</td></tr></table> |
94a2afd0c8982bbdc04df896bccd78fcd51de67b8914d1dbb4e5bbd782df4ccb.png | complex | <table><tr><td rowspan="2">Cell lines</td><td rowspan="2">Tissue</td><td colspan="2">Bozepinib</td></tr><tr><td>IC<sub>50</sub> (μM)</td><td>TI</td></tr><tr><td>MCF-7<sup>a</sup></td><td>Breast cancer</td><td>0,355 ± 0,011</td><td>5,14</td></tr><tr><td>MDA-MB 231<sup>a</sup></td><td>Breast cancer</td><td>0,166 ± 0,063</td><td>11</td></tr><tr><td>MDA-MB 468</td><td>Breast cancer</td><td>0,850 ± 0,003</td><td>2,14</td></tr><tr><td>SKBR-3</td><td>Breast cancer</td><td>0,330 ± 0,003</td><td>5,53</td></tr><tr><td>MCF-10A<sup>a</sup></td><td>Normal breast</td><td>1,825 ± 0,003</td><td>ND<sup>b</sup></td></tr><tr><td>Caco-2</td><td>Colon cancer</td><td>0,631 ± 0,008</td><td>3,18</td></tr><tr><td>T-84</td><td>Colon cancer</td><td>1,019 ± 0,281</td><td>1,97</td></tr><tr><td>HT-29</td><td>Colon cancer</td><td>1,352 ± 0,281</td><td>1,48</td></tr><tr><td>SW-480</td><td>Colon cancer</td><td>0,235 ± 0,011</td><td>8,56</td></tr><tr><td>HCT-116</td><td>Colon cancer</td><td>0,570 ± 0,020</td><td>3,52</td></tr><tr><td>CCD-18Co</td><td>Normal colon</td><td>2,012 ± 0,012</td><td>ND<sup>b</sup></td></tr></table> |
bddacd52f2324982740f2dfbb091a4b31b7045a925400cb2ce32963b659fbf82.png | complex | <table><tr><td></td><td colspan="3">Dutch intervention group</td><td colspan="3">Dutch control group</td><td colspan="3">Suriname</td><td colspan="3">Indonesia</td></tr><tr><td>Time point</td><td>T = 0</td><td>T = 1</td><td>p (χ<sup>2</sup>)</td><td>T = 0</td><td>T = 1</td><td>p (χ<sup>2</sup>)</td><td>T = 0</td><td>T = 1</td><td>p (χ<sup>2</sup>)</td><td>T = 0</td><td>T = 1</td><td>p (χ<sup>2</sup>)</td></tr><tr><td>Gender (%)</td><td>193 (100)</td><td>144 (100)</td><td rowspan="3">0.535</td><td>182 (100)</td><td>133 (100)</td><td rowspan="3">0.955</td><td>142 (100)</td><td>153 (100)</td><td rowspan="3">0.718</td><td>308 (100)</td><td>317 (100)</td><td rowspan="3">0.825</td></tr><tr><td> Boy</td><td>140 (72.5)</td><td>100 (69.4)</td><td>95 (52.2)</td><td>69 (51.9)</td><td>62 (43.7)</td><td>70 (45.8)</td><td>129 (41.9)</td><td>130 (41.0)</td></tr><tr><td> Girl</td><td>53 (27.5)</td><td>44 (30.6)</td><td>87 (47.8)</td><td>64 (48.1)</td><td>80 (56.3)</td><td>83 (54.2)</td><td>179 (58.1)</td><td>187 (59.0)</td></tr><tr><td>Age (%)</td><td>193 (100)</td><td>145 (100)</td><td rowspan="6">0.040</td><td>183 (100)</td><td>132 (100)</td><td rowspan="6">< 0.001</td><td>143 (100)</td><td>153 (100)</td><td rowspan="6">0.693</td><td>311 (100)</td><td>316 (100)</td><td rowspan="6">< 0.001</td></tr><tr><td> < 14</td><td>–</td><td>–</td><td>2 (0.0)</td><td>3 (0.0)</td><td>–</td><td>–</td><td>–</td><td>–</td></tr><tr><td> 14</td><td>100 (51.8)</td><td>55 (37.9)</td><td>78 (42.6)</td><td>27 (20.5)</td><td>1 (0.0)</td><td>0 (0.0)</td><td>4 (0.0)</td><td>2 (0.0)</td></tr><tr><td> 15</td><td>92 (47.7)</td><td>89 (61.4)</td><td>97 (53.0)</td><td>89 (67.4)</td><td>22 (15.4)</td><td>20 (13.1)</td><td>129 (41.5)</td><td>64 (20.3)</td></tr><tr><td> 16</td><td>1 (0.0)</td><td>1 (0.0)</td><td>6 (0.1)</td><td>13 (9.9)</td><td>52 (36.4)</td><td>59 (38.6)</td><td>175 (56.3)</td><td>233 (73.7)</td></tr><tr><td> > 16</td><td>0 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td><td>68 (47.6)</td><td>74 (48.4)</td><td>3 (0.0)</td><td>17 (0.1)</td></tr><tr><td>Education (%)</td><td>193 (100)</td><td>144 (100)</td><td rowspan="3">0.559</td><td>184 (100)</td><td>128 (100)</td><td rowspan="3">0.099</td><td>143 (100)</td><td>153 (100)</td><td>–</td><td>311 (100)</td><td>317 (100)</td><td rowspan="3">–</td></tr><tr><td> HAVO</td><td>73 (37.8)</td><td>50 (34.7)</td><td>50 (27.2)</td><td>46 (35.9)</td><td>0 (0)</td><td>0 (0)</td><td></td><td>311 (100)</td><td>317 (100)</td></tr><tr><td> VWO</td><td>120 (62.2)</td><td>94 (65.3)</td><td>134 (72.8)</td><td>82 (64.1)</td><td>143 (100)</td><td>153 (100)</td><td></td><td>0 (0)</td><td>0 (0)</td></tr><tr><td>Science</td><td>190 (100)</td><td>146 (100)</td><td rowspan="4">0.719</td><td>184 (100)</td><td>133 (100)</td><td rowspan="4">0.215</td><td>142 (100)</td><td>150 (100)</td><td rowspan="4">0.959</td><td>310 (100)</td><td>316 (100)</td><td rowspan="4">0.024</td></tr><tr><td> Nonscience</td><td>44 (23.2)</td><td>39 (26.7)</td><td>107 (58.2)</td><td>73 (54.9)</td><td>29 (20.4)</td><td>31 (20.7)</td><td>55 (17.7)</td><td>36 (11.4)</td></tr><tr><td> Science</td><td>144 (75.8)</td><td>105 (71.9)</td><td>77 (41.8)</td><td>60 (45.1)</td><td>113 (79.6)</td><td>119 (79.3)</td><td>255 (82.3)</td><td>280 (88.6)</td></tr><tr><td> Don't know</td><td>2 (0.0)</td><td>2 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td><td>0 (0.0)</td></tr></table> |
407e2c470472b273c0c3dbc94bcdef58d7bd7ae22688cbaba3b7bcaedde918ef.png | complex | <table><tr><td rowspan="2">Absolute change in</td><td colspan="4">One-way travel time by automobile to SPH, min</td></tr><tr><td><45 (<i>n</i> = 69)</td><td>45–150 (<i>n</i> = 25)</td><td>150–360 (<i>n</i> = 39)</td><td>>360 (<i>n</i> = 11)</td></tr><tr><td>FEV1 % predicted/year</td><td>−0.9 [−1.6, 0.1]</td><td>−0.5 [−1.8, 0.8]</td><td>0.1 [−1.0, 1.2]</td><td>−3.1<sup><i>∗</i></sup> [−5.1, −1.1] </td></tr><tr><td>BMI (kg/m<sup>2</sup>)/year</td><td>0.0 [−0.1, 0.1]</td><td>0.1 [−0.2, 0.3]</td><td>0.3<sup>£</sup> [0.1, 0.5]</td><td>−0.3 [−0.6, 0.1]</td></tr></table> |
f2364e0e41cb32f317bf36993a63b7f544bbbf3fd262a0ffac4435f9b3420c9c.png | simple | <table><tr><td>Chrom-dataset</td><td>cM</td><td>Nearest Marker</td><td>lodscore</td><td>Chrom-dataset</td><td>cM</td><td>Nearest Marker</td><td>lodscore</td></tr><tr><td>1-1</td><td>102.0</td><td>D1S1665</td><td>1.29</td><td>8-1</td><td>26.0</td><td>D8S1106</td><td>1.59</td></tr><tr><td>1–3</td><td>114.0</td><td>D1S551</td><td>1.10</td><td>8-3</td><td>39.8</td><td>D8S1145</td><td>1.78</td></tr><tr><td>1-1</td><td>140.0</td><td>D1S3723</td><td>1.11</td><td>8-2</td><td>41.2</td><td>D8S136</td><td>2.20</td></tr><tr><td>1–5</td><td>202.0</td><td>D1S518</td><td>1.15</td><td>8-4</td><td>50.4</td><td>D8S136</td><td>1.95</td></tr><tr><td>1–3</td><td>233.0</td><td>D1S2141</td><td>1.13</td><td>9-5</td><td>85.4</td><td>D9S1120</td><td>1.29</td></tr><tr><td>1–4</td><td>233.0</td><td>D1S2141</td><td>1.87</td><td>9-6</td><td>85.4</td><td>D9S1120</td><td>1.78</td></tr><tr><td>1–5</td><td>234.4</td><td>D1S2141</td><td>1.22</td><td>9-1</td><td>114.6</td><td>D9S938</td><td>1.42</td></tr><tr><td>1–6</td><td>235.8</td><td>D1S2141</td><td>1.37</td><td>10-6</td><td>35.6</td><td>D10S1430</td><td>1.81</td></tr><tr><td>2–3</td><td>99.0</td><td>D2S1777</td><td>1.58</td><td>10-4</td><td>38.2</td><td>D10S1430</td><td>1.71</td></tr><tr><td>2–6</td><td>99.0</td><td>D2S1777</td><td>1.81</td><td>10-3</td><td>51.2</td><td>D10S1423</td><td>1.52</td></tr><tr><td>2-2</td><td>145.0</td><td>D2S1334</td><td>1.27</td><td>10-1</td><td>63.0</td><td>D10S1208</td><td>4.23</td></tr><tr><td>2–5</td><td>145.0</td><td>D2S1334</td><td>1.66</td><td>11-1</td><td>106.0</td><td>D11S1986</td><td>1.60</td></tr><tr><td>2-1</td><td>157.2</td><td>D2S1399</td><td>1.46</td><td>11-3</td><td>119.0</td><td>D11S4464</td><td>2.43</td></tr><tr><td>3–5</td><td>22.0</td><td>D3S1304</td><td>1.00</td><td>11-4</td><td>119.0</td><td>D11S4464</td><td>1.71</td></tr><tr><td>3-3</td><td>74.2</td><td>D3S2409</td><td>1.34</td><td>11-5</td><td>119.0</td><td>D11S4464</td><td>2.29</td></tr><tr><td>3-2</td><td>77.4</td><td>D3S1766</td><td>1.17</td><td>11-2</td><td>124.6</td><td>D11S4464</td><td>3.51</td></tr><tr><td>3-2</td><td>170.6</td><td>D3S1763</td><td>1.02</td><td>11-6</td><td>124.6</td><td>D11S4464</td><td>2.70</td></tr><tr><td>4-3</td><td>93.0</td><td>D4S2361</td><td>2.03</td><td>14-3</td><td>70.6</td><td>D14S592</td><td>1.38</td></tr><tr><td>4-3</td><td>146.0</td><td>D4S1625</td><td>1.62</td><td>14-2</td><td>86.0</td><td>D14S53</td><td>1.60</td></tr><tr><td>4-5</td><td>146.0</td><td>D4S1625</td><td>1.25</td><td>16-2</td><td>24.4</td><td>D16S748</td><td>1.30</td></tr><tr><td>4-6</td><td>146.0</td><td>D4S1625</td><td>1.41</td><td>16-3</td><td>24.4</td><td>D16S748</td><td>1.20</td></tr><tr><td>5-3</td><td>0.0</td><td>D5S392</td><td>2.37</td><td>16-5</td><td>27.2</td><td>D16S764</td><td>1.65</td></tr><tr><td>5-4</td><td>0.0</td><td>D5S392</td><td>1.25</td><td>16-4</td><td>28.6</td><td>D16S764</td><td>1.62</td></tr><tr><td>5-5</td><td>0.8</td><td>D5S2488</td><td>1.52</td><td>16-1</td><td>41.2</td><td>D16S403</td><td>2.33</td></tr><tr><td>5-2</td><td>1.0</td><td>D5S2488</td><td>1.66</td><td>16-2</td><td>61.6</td><td>D16S3396</td><td>1.67</td></tr><tr><td>6-2</td><td>130.8</td><td>D6S1040</td><td>1.53</td><td>18-1</td><td>7.0</td><td>D18S481</td><td>1.72</td></tr><tr><td>6-1</td><td>149.6</td><td>GATA184A08</td><td>4.53</td><td>18-1</td><td>28.0</td><td>D18S843</td><td>1.18</td></tr><tr><td>6-3</td><td>166.0</td><td>D6S305</td><td>1.55</td><td>18-1</td><td>85.4</td><td>D18S1357</td><td>1.06</td></tr><tr><td>6-4</td><td>166.0</td><td>D6S305</td><td>1.62</td><td></td><td></td><td></td><td></td></tr><tr><td>6-5</td><td>166.0</td><td>D6S305</td><td>1.15</td><td></td><td></td><td></td><td></td></tr><tr><td>6-6</td><td>166.0</td><td>D6S305</td><td>3.09</td><td></td><td></td><td></td><td></td></tr></table> |
436fa537059cc4b57d084921c6cd9047a833a9cf1d1c8c860b10878e974dbe89.png | complex | <table><tr><td></td><td colspan="3">Respondents agreeing to each statement</td></tr><tr><td></td><td>Women%</td><td>Men%</td><td>p-value*</td></tr><tr><td>There is often violence at parties</td><td>25</td><td>14</td><td>< 0.001</td></tr><tr><td>Property is often destroyed at parties</td><td>43</td><td>39</td><td>0.08</td></tr><tr><td>There are often accidents with physical injury at parties</td><td>54</td><td>46</td><td>0.008</td></tr><tr><td>I often baby-sit drunk friends</td><td>80</td><td>83</td><td>0.09</td></tr><tr><td>I feel I can talk to a friend about his/her alcohol habits</td><td>89</td><td>90</td><td>0.26</td></tr><tr><td>My sleep is often disturbed due to others partying</td><td>29</td><td>21</td><td>0.001</td></tr><tr><td>My study habits are often disturbed due to others partying</td><td>17</td><td>15</td><td>0.15</td></tr></table> |
4389427c21e489acfceaa34b3d2ae5b50199cddd15140f90bdd7d7ecc0a4df9c.png | simple | <table><tr><td>Complications and outcomes</td><td>Conventional (<i>n </i>= 40)</td><td>Restrictive (<i>n </i>= 41)</td></tr><tr><td>Total complications</td><td>43</td><td>45</td></tr><tr><td>Cardiovascular complications</td><td></td><td></td></tr><tr><td> Atrial fibrillation</td><td>2 (4.6)</td><td>1 (2.2)</td></tr><tr><td> Hypertensive crisis</td><td>4 (9.3)</td><td>0 (0)</td></tr><tr><td> Pulmonary thromboembolism</td><td>0 (0)</td><td>1 (2.2)</td></tr><tr><td> Total</td><td>6 (13.9)</td><td>2 (4.4)</td></tr><tr><td>Tissue-healing complications</td><td></td><td></td></tr><tr><td> Evisceration</td><td>2 (4.6)</td><td>0 (0)</td></tr><tr><td> Anastomotic leak</td><td>2 (4.6)</td><td>1 (2.4)</td></tr><tr><td> Total</td><td>4 (9.3)</td><td>1 (2.4)</td></tr><tr><td>Infectious complications</td><td></td><td></td></tr><tr><td> Nosocomial pneumonia</td><td>4 (9.3)</td><td>6 (13.3)</td></tr><tr><td> Occult septic shock</td><td>1 (2.3)</td><td>0 (0)</td></tr><tr><td> Peritonitis</td><td>2 (4.6)</td><td>0 (0)</td></tr><tr><td> Blood stream infection</td><td>0 (0)</td><td>1 (2.2)</td></tr><tr><td> Wound abscess</td><td>2 (4.6)</td><td>0 (0)</td></tr><tr><td> Total</td><td>9</td><td>7</td></tr><tr><td>Other complications</td><td></td><td></td></tr><tr><td> Extubation failure</td><td>1 (2.3)</td><td>0 (0)</td></tr><tr><td> Renal dysfunction</td><td>1 (2.3)</td><td>0 (0)</td></tr><tr><td> Gastrointestinal dysfunction</td><td>3 (6.9)</td><td>1 (2.2)</td></tr><tr><td> Total</td><td>5</td><td>1</td></tr><tr><td>Total number of major complications</td><td>24</td><td>11</td></tr><tr><td>Number of patients with complications</td><td>18 (41.8)</td><td>9 (20.0)*</td></tr><tr><td>Number of complications per patient</td><td>0.55</td><td>0.24</td></tr><tr><td>Outcomes</td><td></td><td></td></tr><tr><td> LOS in the ICU</td><td>2.0 [1.0 to 4.0]</td><td>2.0 [2.0 to 5.0]</td></tr><tr><td> LOS in the hospital</td><td>6.0 [4.0 to 9.0]</td><td>6.0 [4 to 10]</td></tr><tr><td> 30-day mortality rate</td><td>2 (4.6)</td><td>0 (0)</td></tr><tr><td> 60-day mortality rate</td><td>3 (6.9)</td><td>1 (2.2)</td></tr></table> |
35b79abe3bca8fddfc1e784277c9d0cdaf5994f4e44e3e5cfae2b9dba8023020.png | complex | <table><tr><td>Type of cost</td><td>Identification</td><td colspan="2">Measurement</td><td colspan="2">Valuation</td></tr><tr><td></td><td>Categories</td><td>Costing method</td><td>Sources of data</td><td>Valuation method</td><td>Sources of data</td></tr><tr><td>Recurrent</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Personnel</td><td>Administration and management, clinical staff (doctors, nurses, lay workers*), and support staff (cleaning)</td><td>Percentage of time spent on different activities</td><td>Observation** and semi-structured interviews with providers</td><td>Total remuneration package costs</td><td>Provider expenditure reports</td></tr><tr><td>Supplies</td><td>Sputum and culture tests, x-rays and drugs</td><td>Quantity consumed</td><td>Patient records</td><td>Market prices</td><td>Provincial and private laboratories and pharmacy price lists</td></tr><tr><td>Vehicle operating and maintenance</td><td>Vehicle running costs</td><td>Number of kilometres travelled</td><td>Vehicle logbook, interview with clinic manager</td><td>Actual expenditure on fuel, oil and maintenance</td><td>Automobile Association rates</td></tr><tr><td>Building operating and maintenance</td><td>Overheads (water, electricity, telephone, fax, stationeries etc)</td><td>Proportion of total visits for which TB patients accounted</td><td>Actual costs from facility records, interview with clinic manager</td><td>Actual expenditure</td><td>Provider expenditure reports</td></tr><tr><td>Capital<sup>†</sup></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Buildings</td><td>Offices, clinics and hospitals</td><td>Proportion of total visits for which TB patients accounted</td><td>Interview with clinic manager</td><td>Replacement prices</td><td>CSIR Building and Construction Technology</td></tr><tr><td>Equipment</td><td>Furniture, medical and non-medical equipment</td><td>Proportion of total visits for which TB patients accounted)</td><td>Interview with clinic manager</td><td>Replacement prices</td><td>Local manufacturers</td></tr><tr><td>Vehicles</td><td>Vehicles used for TB patients</td><td>Vehicle utilisation (km travelled)</td><td>Vehicle log book, interview with clinic manager</td><td>Replacement prices</td><td>Local car dealers</td></tr><tr><td>Training</td><td>Community "treatment supporters" training</td><td>Number of treatment supporters trained</td><td>Actual costs from NGO records</td><td>Actual expenditure</td><td>Provider expenditure reports</td></tr></table> |
1369e61cfa960ba924c5e2d6b2673bb825bb6267a994759c384bc8379aaa46cc.png | simple | <table><tr><td></td><td>No hypotension</td><td>iNIBP</td><td>dNIBP</td><td><i>p</i> value</td></tr><tr><td>The number of cases in which hypotension was detected faster (<i>n</i> (%))</td><td>24</td><td>47 (61.8)</td><td>29 (38.2)</td><td>0.03</td></tr></table> |
406355fd7b696b01e9a12b31e243c6b0be53388a696e328758e802d26971a06c.png | complex | <table><tr><td></td><td colspan="2">Activity (U/ml)<sup>1</sup></td><td></td><td></td><td></td><td></td></tr><tr><td>Enzymes</td><td>Soluble fraction</td><td>Insoluble fraction</td><td>Percent of activity found in insoluble fraction<sup>2</sup></td><td>Enzyme amount (mg/ml)<sup>3</sup></td><td>Specific activity (U/mg enzyme)<sup>3</sup></td><td>Specific activity relative to the native enzyme<sup>3</sup></td></tr><tr><td>AMA</td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td> AMA-native</td><td>734.4 ± 37.5</td><td>9.63 ± 2.29</td><td>1.3%</td><td>0.47</td><td>1563</td><td>100%</td></tr><tr><td> AMA-ELK16</td><td>66.7 ± 5.1</td><td>468.7 ± 12.9</td><td>87.5%</td><td>0.25</td><td>1875</td><td>120%</td></tr><tr><td>XynB</td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td> XynB-native</td><td>398.8 ± 9.7</td><td>136.2 ± 17.0</td><td>25.4%</td><td>0.31</td><td>1290</td><td>100%</td></tr><tr><td> XynB-ELK16</td><td>13.6 ± 0.6</td><td>230.0 ± 9.8</td><td>94.4%</td><td>0.23</td><td>991</td><td>77%</td></tr></table> |
5ee9d43d334a578834cb4ce8797e50700b814407945e73dcd9f987b1796b3cd5.png | simple | <table><tr><td> </td><td>Multivariable logistic regression analysis (n = 362)</td></tr><tr><td><i>Sociodemographic factors</i></td><td>aOR (95%-CI)<sup>a</sup></td></tr><tr><td>Age (continuous)</td><td>1.03 (1.00-1.05)</td></tr><tr><td><i>Health-related factors</i></td><td> </td></tr><tr><td>Current smoker</td><td> </td></tr><tr><td> Yes</td><td>2.31 (1.27-4.23)</td></tr><tr><td> Not anymore</td><td>1.13 (0.66-1.95)</td></tr><tr><td> Never smoked</td><td>(Reference)</td></tr><tr><td>Ever had a diagnosed depression/depressive mood</td><td> </td></tr><tr><td> Yes</td><td>1.85 (1.12-3.06)</td></tr><tr><td> No</td><td>(Reference)</td></tr><tr><td><i>Work-related exposures</i></td><td> </td></tr><tr><td>Carrying and lifting heavy loads (> 20 kg)</td><td> </td></tr><tr><td> Frequently</td><td>2.69 (1.53-4.75)</td></tr><tr><td> Sometimes</td><td>1.26 (0.68-2.34)</td></tr><tr><td> Rarely/Never</td><td>(Reference)</td></tr><tr><td>Exposure to environmental impacts</td><td> </td></tr><tr><td> Frequently</td><td>2.18 (1.26-3.76)</td></tr><tr><td> Sometimes</td><td>1.76 (0.98-3.13)</td></tr><tr><td> Rarely/Never</td><td>(Reference)</td></tr></table> |
f259e2ee15c1d1d9ec6a26a3d481a987ee1cd63cf7ea46f3d116b971cbdeb92f.png | complex | <table><tr><td rowspan="3">Variable</td><td colspan="3">OR (95 % CI)</td></tr><tr><td rowspan="2">Binary</td><td colspan="2">Multinomial</td></tr><tr><td>Overweight</td><td>Obesity</td></tr><tr><td>Age</td><td>1.09 (1.08, 1.11)</td><td>1.08 (1.07, 1.10)</td><td>1.12 (1.10, 1.15)</td></tr><tr><td colspan="4">Marital status<sup>a</sup></td></tr><tr><td> With partner</td><td>1.32 (1.07, 1.63)</td><td>1.23 (0.98, 1.53)</td><td>1.64 (1.22, 2.21)</td></tr><tr><td colspan="4">Race/colour<sup>b</sup></td></tr><tr><td> Brown</td><td>0.56 (0.39, 0.82)</td><td>0.60 (0.41, 0.88)</td><td>0.47 (0.29, 0.76)</td></tr><tr><td> White</td><td>0.41 (0.28, 0.58)</td><td>0.43 (0.30, 0.62)</td><td>0.36 (0.23, 0.56)</td></tr><tr><td colspan="4">Mother’s schooling<sup>c</sup></td></tr><tr><td> 9–11 years</td><td>1.09 (0.86, 1.38)</td><td>1.00 (0.78, 1.28)</td><td>1.37 (0.98, 1.91)</td></tr><tr><td> 12 or more years</td><td>1.40 (1.04, 1.89)</td><td>1.16 (0.84, 1.59)</td><td>2.22 (1.50, 3.30)</td></tr><tr><td colspan="4">Domestic overload<sup>d</sup></td></tr><tr><td> High</td><td>1.60 (1.28, 1.99)</td><td>1.52 (1.21, 1.92)</td><td>1.80 (1.34, 2.42)</td></tr><tr><td>Years worked at night</td><td>1.00 (0.98, 1.02)</td><td>0.99 (0.97, 1.01)</td><td>1.02 (0.99, 1.04)</td></tr><tr><td colspan="4">Self-rated health<sup>e</sup></td></tr><tr><td> Poor</td><td>2.17 (1.74, 2.70)</td><td>1.83 (1.45, 2.31)</td><td>3.31 (2.47, 4.44)</td></tr><tr><td colspan="4">Consumption of fried food<sup>f</sup></td></tr><tr><td> 1–3×/month</td><td>1.96 (1.30, 2.95)</td><td>1.81 (1.18, 2.77)</td><td>2.44 (1.34, 4.43)</td></tr><tr><td> 1–3×/week</td><td>1.69 (1.13, 2.54)</td><td>1.44 (0.94, 2.20)</td><td>2.62 (1.45, 4.73)</td></tr><tr><td> 4–6×/week</td><td>2.44 (1.05, 3.96)</td><td>2.21 (1.33, 3.66)</td><td>3.23 (1.61, 6.45)</td></tr><tr><td> Daily</td><td>2.05 (1.16, 3.63)</td><td>1.90 (1.05, 3.43)</td><td>2.49 (1.11, 5.58)</td></tr><tr><td colspan="4">Physical inactivity<sup>g</sup></td></tr><tr><td> Yes</td><td>1.58 (1.26, 1.99)</td><td>1.44 (1.13, 1.83)</td><td>2.07 (1.49, 2.87)</td></tr><tr><td>BMI at age 20 years</td><td>1.63 (1.55, 1.71)</td><td>1.52 (1.44, 1.60)</td><td>1.95 (1.83, 2.07)</td></tr></table> |
144502df7f4471fc1307ad19179870f343d597750607eb943de70bfe30b98b1e.png | simple | <table><tr><td>UniProt ID</td><td>Species Name</td><td>Protein Name</td><td>e-value</td><td>Similarity</td></tr><tr><td>Q9XKY50</td><td><i>Phytomonas serpens</i></td><td>MURF1</td><td>5.3e<sup>-148</sup></td><td>100.0%</td></tr><tr><td>Q33559</td><td><i>Leishmania tarentolae</i></td><td>MURF1</td><td>2.7e<sup>-109</sup></td><td>90.9%</td></tr><tr><td>Q8HE85</td><td><i>Trypanosoma sp.</i></td><td>MURF1</td><td>3.1e<sup>-17</sup></td><td>87.6%</td></tr><tr><td>Q33547</td><td><i>Blastocrithidia culicis</i></td><td>MURF1</td><td>1.2e<sup>-16</sup></td><td>86.5%</td></tr><tr><td>Q33552</td><td><i>Crithidia fasciculata</i></td><td>MURF1</td><td>6e<sup>-16</sup></td><td>88.4%</td></tr><tr><td>Q33556</td><td><i>Herpetomonas muscarum</i></td><td>MURF1</td><td>5.1e<sup>-13</sup></td><td>85.0%</td></tr><tr><td>Q34937</td><td><i>Leishmania. tarentolae</i></td><td>MURF2</td><td>2e<sup>-09</sup></td><td>60.4%</td></tr><tr><td>Q34096</td><td><i>Crithidia fasciculata</i></td><td>MURF2</td><td>3.2e<sup>-09</sup></td><td>56.3%</td></tr><tr><td>Q34192</td><td><i>Crithidia oncopelti</i></td><td>NAD5</td><td>3.8e<sup>-09</sup></td><td>54.5%</td></tr><tr><td>P48903</td><td><i>Chondrus crispus</i></td><td>NAD2</td><td>5.4e<sup>-07</sup></td><td>57.9%</td></tr><tr><td>Q5LRX2</td><td><i>Silicibacter pomeroyi</i></td><td>Putative membrane protein</td><td>1.2e<sup>-06</sup></td><td>58.0%</td></tr><tr><td>Q6E773</td><td><i>Saprolegnia ferax</i></td><td>NAD2</td><td>1.5e<sup>-06</sup></td><td>53.8%</td></tr><tr><td>Q6SKY5</td><td><i>Speleonectes tulumensis</i></td><td>NAD5</td><td>2.3e<sup>-06</sup></td><td>55.2%</td></tr><tr><td>Q5AG49</td><td><i>Candida albicans</i></td><td>Hypothetical protein</td><td>3.3e<sup>-06</sup></td><td>67.7%</td></tr><tr><td>Q5AGI5</td><td><i>Candida albicans</i></td><td>Hypothetical protein</td><td>7.1e<sup>-06</sup></td><td>67.9%</td></tr><tr><td>Q8SKS6</td><td><i>Ancylostoma duodenale</i></td><td>NAD4</td><td>7.4e<sup>-06</sup></td><td>57.3%</td></tr><tr><td>Q85TH7</td><td><i>Melipona bicolor</i></td><td>NAD4</td><td>7.7e<sup>-06</sup></td><td>58.1%</td></tr><tr><td>Q33575</td><td><i>Trypanosoma brucei</i></td><td>NAD4</td><td>8.7e<sup>-06</sup></td><td>57.3%</td></tr><tr><td>P24499</td><td><i>Trypanosoma brucei brucei</i></td><td>ATP6</td><td>1.1e<sup>-05</sup></td><td>55.4%</td></tr><tr><td>Q70NW4</td><td><i>Strongyloides stercoralis</i></td><td>NAD4</td><td>1.2e<sup>-05</sup></td><td>56.7%</td></tr><tr><td>Q33570</td><td><i>Trypanosoma cruzi</i></td><td>ATP6</td><td>1.5e<sup>-05</sup></td><td>56.9%</td></tr><tr><td>Q5CV17</td><td><i>Cryptosporidium parvum</i></td><td>Hypothetical protein</td><td>1.5e<sup>-05</sup></td><td>61.5%</td></tr><tr><td>Q057W5</td><td><i>Buchnera aphidicola</i></td><td>NADH dehydrogenase I chain L</td><td>1.9e<sup>-05</sup></td><td>54.9%</td></tr><tr><td>Q8IBJ6</td><td><i>Plasmodium falciparum</i></td><td>Hypothetical protein</td><td>2.9e<sup>-05</sup></td><td>58.4%</td></tr></table> |
dfdf485b7bf3226b0b3cab2cc1d1f82b2708875a623254ed257c8a5c918f1361.png | complex | <table><tr><td>Algal species</td><td>Molecular technique</td><td>Bacterial phyla</td><td>Country origin</td><td>Reference</td></tr><tr><td colspan="5">CHLOROPHYTA</td></tr><tr><td><i>Bryopsis hypnoides</i></td><td>CLO, FISH</td><td>BA, FI, PR (al, ep, ga)</td><td>Mexico</td><td>Hollants et al. (2011a,b)</td></tr><tr><td><i>Bryopsis pennata</i></td><td>CLO, FISH</td><td>BA, FI, PR (al, ep, ga)</td><td>Mexico</td><td>Hollants et al. (2011a,b)</td></tr><tr><td><i>Caulerpa taxifolia</i></td><td>CLO, RFLP</td><td>BA, PR (al, be, de, ga)</td><td>4 Countries</td><td>Meusnier et al. (2001)</td></tr><tr><td><i>Chara aspera</i></td><td>FISH</td><td>AC, BA, PL, PR (al, be, ga)</td><td>Germany</td><td>Hempel et al. (2008)</td></tr><tr><td><i>Desmidium grevillii</i></td><td>CLO</td><td>BA, PR (al, be, ga)</td><td>USA</td><td>Fisher et al. (1998)</td></tr><tr><td><i>Halimeda opuntia</i></td><td>CLO</td><td>AC, BA, CH, CL, CY, FI, PL, PR</td><td>N. Antilles</td><td>Barott et al. (2011)</td></tr><tr><td><i>Hyalotheca dissiliens</i></td><td>CLO</td><td>BA, PR (al, be, ga)</td><td>USA</td><td>Fisher et al. (1998)</td></tr><tr><td><i>Spondylosium pulchrum</i></td><td>CLO</td><td>BA, PR (al, be, ga)</td><td>USA</td><td>Fisher et al. (1998)</td></tr><tr><td><i>Ulva australis</i></td><td>CLO, DGGE</td><td>AC, BA, PL, PR (al, de, ga)</td><td>Australia</td><td>Longford et al. (2007)</td></tr><tr><td><i>Ulva australis</i></td><td>CLO</td><td>AC, BA, CY, PL, PR (al, de, ga), VE</td><td>Australia</td><td>Burke et al. (2011b)</td></tr><tr><td><i>Ulva australis</i></td><td>CFISH, DGGE</td><td>BA, PR (al, ga)</td><td>Australia</td><td>Tujula et al. (2010)</td></tr><tr><td><i>Ulva intestinalis</i></td><td>CLO, DGGE</td><td>AC, BA, PR (al, de, ep, ga), VE</td><td>Germany</td><td>Lachnit et al. (2011)</td></tr><tr><td><i>Ulva prolifera</i></td><td>CLO, DGGE</td><td>AC, BA, CY, FI, FU, PL, PR (al, be, de, ep, ga), SP, VE</td><td>China</td><td>Liu et al. (2011)</td></tr><tr><td colspan="5">HETEROKONTOPHYTA</td></tr><tr><td><i>Dictyota bartayresiana</i></td><td>CLO</td><td>AC, BA, CH, CL, CY, FI, PL, PR</td><td>N. Antilles</td><td>Barott et al. (2011)</td></tr><tr><td><i>Fucus vesiculosus</i></td><td>CLO, DGGE</td><td>BA, CY, PL, PR (al, be, de, ep, ga), VE</td><td>Germany</td><td>Lachnit et al. (2011)</td></tr><tr><td><i>Laminaria hyperborea</i></td><td>DGGE, FISH</td><td>AC, BA, CY, PL, PR (al, be, ga), VE</td><td>Norway</td><td>Bengtsson et al. (2010)</td></tr><tr><td><i>Laminaria rodriguezii</i></td><td>CLO</td><td>AR*, PR (be)</td><td>Spain</td><td>Trias et al. (2012)</td></tr><tr><td><i>Saccharina latissima</i></td><td>CLO, DGGE</td><td>BA, PR (al, ga)</td><td>Germany</td><td>Staufenberger et al. (2008)</td></tr><tr><td colspan="5">RHODOPHYTA</td></tr><tr><td>Coralline crustose</td><td>CLO</td><td>AC, BA, CH, CL, CY, FI, PL, PR</td><td>N. Antilles</td><td>Barott et al. (2011)</td></tr><tr><td><i>Delisea pulchra</i></td><td>CLO, DGGE</td><td>AC, BA, CH, CY, PL, PR (al, de, ga), VE</td><td>Australia</td><td>Longford et al. (2007)</td></tr><tr><td><i>Delisea pulchra</i></td><td>CLO, DGGE</td><td>BA, PL, PR (al, ga)</td><td>Australia</td><td>Fernandes (2011)</td></tr><tr><td><i>Gracilaria vermiculophylla</i></td><td>CLO, DGGE</td><td>AC, CY, DT, PL, PR (al, be, de)</td><td>Germany</td><td>Lachnit et al. (2011)</td></tr><tr><td><i>Osmundaria volubilis</i></td><td>CLO</td><td>AR*, PR (be)</td><td>Spain</td><td>Trias et al. (2012)</td></tr><tr><td><i>Phyllophora crispa</i></td><td>CLO</td><td>AR*, PR (be)</td><td>Spain</td><td>Trias et al. (2012)</td></tr><tr><td><i>Porphyra yezoensis</i></td><td>CLO</td><td>BA, LE, PR (al, be, ga)</td><td>Japan</td><td>Namba et al. (2010)</td></tr><tr><td>3 spp. macroalgae</td><td>CLO, TRFLP</td><td>BA, CY, PL, PR (al, ga), VE</td><td>Chile</td><td>Hengst et al. (2010)</td></tr><tr><td>12 spp. macroalgae</td><td>CLO</td><td>PL</td><td>Portugal</td><td>Lage and Bondoso (2011)</td></tr><tr><td>Unidentified turf algae</td><td>CLO</td><td>AC, BA, CH, CL, CY, FI, PL, PR</td><td>N. Antilles</td><td>Barott et al. (2011)</td></tr></table> |
1db38825baf696e908391d74b3efc42eda555d1b44292af567ae3fff4b21be17.png | complex | <table><tr><td rowspan="2"> </td><td rowspan="2">Type 2 diabetes phenotype A (n = 77)</td><td rowspan="2">Type 2 diabetes phenotype B (n = 45)</td><td>Control group</td><td>ANOVA</td></tr><tr><td>(n = 54)</td><td>p-value</td></tr><tr><td>Age (years)</td><td>60 ± 11</td><td>56 ± 11 <sup>a</sup></td><td>56 ± 14 <sup>a</sup></td><td>0.108</td></tr><tr><td>Male (%)</td><td>65.9</td><td>64.6</td><td>57.4 <sup>a, b</sup></td><td><0.001</td></tr><tr><td>BMI (kg/m2)</td><td>29.6 ± 6.2</td><td>31.1 ± 4 <sup>a</sup></td><td>25.9 ± 3.6 <sup>a, b</sup></td><td><0.001</td></tr><tr><td>Waist (cm)</td><td>104 ± 15</td><td>108 ± 13 <sup>a</sup></td><td>92 ± 11 <sup>a, b</sup></td><td><0.001</td></tr><tr><td>Diabetes duration (years)</td><td>12 ± 11</td><td>9 ± 8 <sup>a</sup></td><td>-</td><td> </td></tr><tr><td>Insulin use (%)</td><td>58</td><td>52 <sup>a</sup></td><td>-</td><td> </td></tr><tr><td>Lipid lowering drugs (%)</td><td>30</td><td>28</td><td>-</td><td> </td></tr><tr><td>HbA1c (%)</td><td>9.1 ± 2.1</td><td>9.6 ± 2.3 <sup>a</sup></td><td>5.3 ± 0.6 <sup>a, b</sup></td><td><0.001</td></tr><tr><td>Hypertension (%) <sup>1</sup></td><td>69.4</td><td>68.2</td><td>-</td><td> </td></tr><tr><td>Retinopathy (%)</td><td>29.6</td><td>29.5</td><td>-</td><td> </td></tr><tr><td>Albuminuria (%)</td><td>24</td><td>29.6 <sup>a</sup></td><td>-</td><td> </td></tr><tr><td>Coronary heart disease (%) <sup>2</sup></td><td>5.6</td><td>15.9 <sup>a</sup></td><td>-</td><td> </td></tr><tr><td>Total cholesterol (mmol/L)</td><td>4.78 ± 1.09</td><td>5.64 ± 1.53 <sup>a</sup></td><td>5.00 ± 0.79 <sup>b</sup></td><td>0.004</td></tr><tr><td>Triglycerides (mmol/L)</td><td>1.46 ± 0.79</td><td>3.89 ± 3.30 <sup>a</sup></td><td>0.87 ± 0.37 <sup>a,b</sup></td><td><0.001</td></tr><tr><td>VLDLc (mmol/L)</td><td>0.65 ± 0.30</td><td>1.43 ± 1.12 <sup>a</sup></td><td>0.40 ± 0.17 <sup>a,b</sup></td><td><0.001</td></tr><tr><td>LDLc (mmol/L)</td><td>2.86 ± 0.95</td><td>3.10 ± 0.96 <sup>a</sup></td><td>2.94 ± 0.66 <sup>b</sup></td><td>0.281</td></tr><tr><td>HDLc (mmol/L)</td><td>1.28 ± 0.33</td><td>1.02 ± 0.27 <sup>a</sup></td><td>1.64 ± 0.37 <sup>a,b</sup></td><td><0.001</td></tr><tr><td>NEFA (mmol/L)</td><td>0.64 ± 0.29</td><td>0.90 ± 0.48</td><td>0.41 ± 0.19 <sup>a,b</sup></td><td><0.001</td></tr><tr><td>apoB (g/L)</td><td>0.93 ± 0.32</td><td>1.09 ± 0.28 <sup>a</sup></td><td>0.80 ± 0.19 <sup>a,b</sup></td><td><0.001</td></tr><tr><td>apoA-I (g/L)</td><td>1.46 ± 0.24</td><td>1.37 ± 0.25 <sup>a</sup></td><td>1.57 ± 0.31 <sup>a,b</sup></td><td>0.001</td></tr><tr><td>apoA-II (g/L)</td><td>0.33 ± 0.07</td><td>0.34 ± 0.06</td><td>0.35 ± 0.05</td><td>0.081</td></tr><tr><td>LDL size (nm)</td><td>26.0 ± 0.4</td><td>25.0 ± 0.4 <sup>a</sup></td><td>26.3 ± 0.1 <sup>b</sup></td><td><0.001</td></tr></table> |
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