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"The method allows to detect a series of relevant anatomical/pathological structures in fundus pictures (such as the retinal vessels, the optic disc, hemorrhages, microaneurysms and soft/hard exudates)." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The adversarial loss allows to leverage complementary data sets that do not have all the regions of interest segmented." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Thus, it is not necessary to have all the classes annotated in all the images but to have the labels at least in some of them." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The strategy proposed to tackle this issue is not novel as adversarial losses have been used before for image segmentations." "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"However, it is the first time that it is applied for complementing data sets and have some interesting modifications that certainly ensures novelty in the proposal" "['non', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"The paper is well written and organized, with minor details to address in this matter (see CONS)." "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The clear contribution of the article is, in my opinion, the ability to exploit complementary information from different data sets." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Taking this into account, I would suggest the authors to incorporate at least one paragraph in Related works (Section 2) describing the current existing approaches to do that." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"It is not clear from the explanation in Section 3.1 how the authors deal with the differences in resolution between DRIVE and IDRID data sets" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"It would be interesting to know that aspect, as it is crucial to allow the network to learn to ""transfer"" its own ability for detecting a new region from one data set to another." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The segmentation architecture does not use batch normalization." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Is there a reason for not using it?" "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The vessel segmentation performance is evaluated on the DRIVE data set." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Despite the fact that this set has been the standard for evaluating blood vessel segmentation algorithms since 2004, the resolution of the images is extremelly different from the current ones" "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"I would suggest to incorporate results on at least one of these data sets to better understand the behavior of the algorithm on these images." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The area under the ROC curve is not a proper metric for evaluating a vessel segmentation algorithm due to the class imbalance between the TP and TN classes (vessels vs. background ratio is around 12% in fundus pictures)" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"The method in [2] should be included in the comparison of vessel segmentation algorithms" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"The authors of [2] provided a website with all the results on the DRIVE database (pseudo-url), so their segmentations could be taken from there." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"However, since IDRID does not have vessel annotations, it is not possible to quantify the performance there." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"It would be interesting to simulate such an experiment by taking an additional data set with vessel annotations (e.g., some of those that I suggested before, HRF, CHASEDB1 or DR HAGIS) and evaluate the performance there, without using any of their images for training" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"That would be equivalent to assume that the new data set(s) does (do) not contain the annotations, and will allow to quantify the performance there." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Since the HRF data set contains images from normal, glaucomatous and diabetic retinopathy patients, I would suggest to use that one." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"A similar experiment can be made using other data sets with red/bright lesions (e.g. e-ophtha, pseudo-url) or optic disc annotations (e.g. REFUGE database, pseudo-url)." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"I think this is a key experiment, really necessary to validate if the method is performing well or not" "['non', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"I would certainly accept the paper is this experiment were included and the results were convincing." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"It is not clear if the values for the existing methods in Table 2 correspond to the winning teams of the IDRID challenge" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"The first 10 lines contains too much wording for a statement that should be much easier to explain" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"ii) Learning to leverage the information of complementary data sets is a challenging task." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"iii) Explanation of the method... [1] Zhao, Yitian, et al. ""Automated Vessel Segmentation Using Infinite Perimeter Active Contour Model with Hybrid Region Information with Application to Retinal Images.""" "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Imaging 34.9 (2015): 1797-1807." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"2] Maninis, Kevis-Kokitsi, et al. ""Deep retinal image understanding.""" "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Springer, Cham, 2016." "['non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The approach is clearly explained and the results presented are sufficient to give merit to the idea" "['arg', 'arg', 'arg', 'arg', 'arg', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"No public implementation of the method is provided, which would be a nice extra" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"In my view, the proposed methods are not completely novel , I think the authors are suggested to cite them, just name a few." "['non', 'non', 'non', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Predicting the confidence map with fully convolutional networks was initially done by : ""Microscopy Cell Counting with Fully Convolutional Regression Networks"", W. Xie, J.A." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Noble, A. Zisserman, In MICCAI 2015 Workshop." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The proposed localisation map is actually the result of distance transform, and has been initially used in : ""Counting in The Wild"", C. Arteta, V. Lempitsky, A. Zisserman, In ECCV 2016." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"This paper attempt to do nuclei segmentation in a weakly supervised fashion, using point annotations." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The paper is very well written and easy to follow ; figure 1 does an excellent job at summarizing the method" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"The idea is to generate two labels maps from the points: a Voronoi partitioning for the first one, and a clustering between foreground, background and neutral classes for the second." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Those maps are used for training with a partial cross-entropy." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The trained network is then fine tuned with a direct CRF loss, as in Tang et al. Evaluation is performed on two datasets in several configurations (with and without CRF loss, and variation on the labels used) ; showing the effects of the different parts of the method." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The best combination (both labels + CRF) are close or on par with full supervision." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"The authors also compare the annotation time between points, bounding boxes and full supervision, which really highlight the impact of their method (x10 speedup)" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg']" "paper quality"
"Few questions: - Since the method is quite simple and elegant , I expect it could be adapted to other tasks." "['non', 'non', 'non', 'non', 'non', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Do you have any ideas in mind ?" "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"How resilient is the method to ""forgotten"" nuclei ; i.e. nucleus without a point in the labels ?" "['arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'arg', 'non']" "paper quality"
"It is improving the final performances, speeding up convergence, both ?" "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"
"Minor improvements for the camera ready version, in no particular order: Tang et al. 2018 was actually published at ECCV 2018, the bibliographic entry should be updated." "['non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non', 'non']" "paper quality"