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hello i've had a cold for almost three weeks. it started off as a cough and i though it was getting better by week 2 but then came a runny nose & last weekend i was vomitting. This week I have totally lost my appetite, vomit mucus a little, have a hacking cough, cant hear out of one ear, & cold/hot flashes. Could you please tell me what could be wrong & it i should be examined by a doctor asap?
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What is a typical finding on imaging in patients with Diffuse Axonal Injury?
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I have had a blistery rash that has spread Over my right side, primarily. I have only two small spots on my left side. I have had it for almost weeks. It has cleared up on my face, but is now onmy abdomen, back and top of my thigh. I have been on steroids, oral and topical. I have also used calamine lotion. I have fever and chills at times, am extremely tired all the time and feel like I am in the twilight zone.
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What are the conditions under which physicians may disclose patient information to friends and family members under HIPAA?
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I am 30 years old and Im about to get married in next 6 months. I have a tight fore skin and I want to get circumcision. I live in Bangalore and want to know the best doctor and hospital to get it done.I Also want to know how much time will it take to fully recover. Also is there any laser surgery available for circumcision?
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my sister has a son and when she was pregnant with him, she fainted a few times. she is now 6 months pregnant with twins and she has started to faint again and she had a seizure 2 days ago. she is not epileptic, she has low blood pressure. would that be the cause?
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hi sir am 25 years old nd with height of 5.4 nd weighing 76kgs, last month i had my follicular study and the size remained as14*11 in 15th 17th 19th nd even on 22days, am also using tablts like benforce-m in the mrng nd xplode,duphaston in the night nd also used letoval last month.i want to conceive immediately kindly suggest me on this
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Hi doctor, I am a 28 year old unmarried woman. Last month my period was irregular. I got my periods on the 30th of last month and it was already 20 days later from the actual due. Initially, I had spotting for five days, then I bled for seven days and again, had spotting for three days. Now, I am bleeding again from today on the 27th of this month. Please help me out. My height is 155 cm and weight is 63 kg. I have this complaint once since last month. Normally, my periods will occur in an interval on 40 to 45 days. This is the first time I am experiencing spotting, bleeding and delay. Is this a serious problem?
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I had some food stuck between a tooth, it was uncomfortable. So I flossed it. Now I have a pain lower on my gums near my roots. It isn't swollen, doesn't hurt to chew or drink. It does hurt when I touch it or my lips brush up against it when I talk. I noticed a white line today in the area. It is -near- but not at a tooth I had a root canal done on, 3 months ago. My dentist asked I see the endodontist. But I don't think it has much to do with the same tooth.
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I think I have really bad blood circulation because of many reasons. A) I always feel the temperature more than other people. In the winter, I'm always cold, no matter how many layers I wear. In the summer, I tend to overheat or dehydrate because I sweat so much (gross I know, sorry). B) My legs and arms fall asleep easily. If i sit still for more than a minute or two, I get really bad pins and needles that take a long time to go away or sometime I'll wake up in the middle of the night because I sleep in odd positions and my arms have been above my head for awhile and it feels as if there is no blood in my arms at all. They feel like Harry Potter's arm after that Lockheart guy tries fixing his broken bone - loose, numb, like my muscles can't move anymore, yet my hand and arm functions fine.
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Could you please provide me the current phrasing of the sentence you want me to rephrase?
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The well-established structure of SARS-CoV-2 proteins has opened the door for the drug development of the potent inhibitors. The interaction of spike proteins of the virus with human angiotensin converting enzyme (ACE-2) via receptor binding domain start the journey of the virus in the host cell. The entry of corona virus by endocytosis is followed by genomic replication, transcription and formation of the positive sense RNA. The assembling of genomic material with viral structure proteins, endoplasmic reticulum & golgi intermediate forms mature viron, which on exocytosis completes the SARS-CoV-2 life cycle. The entire cycle highlights the importance of different proteins involved in functioning and virulence of the virus. Targeting some of these proteins such as spike proteins, 3C like protease (3CL pro), papaine like protease (PL pro), helicase, RNA dependent RNA polymerase (RdRp) and N protein plays important role in the development of the antiviral drugs. Using computational approach the researchers are investigating important targets interaction with ligands (novel or existing) for the development of potent antiviral drugs. Number of existing FDA approved drug molecules are repurposed against 3CL pro, PL pro, RdRp and few of them, e.g. remdisivir, favipiravir and lvermectin, are currently used in clinical application against SARS-CoV-2. Numbers of small molecules libraries are also high through output screened for the identification of novel ligand molecule for new drug development. In the present chapter various approaches and strategies for the development of antiviral drugs using the computation tools has been highlighted for the main targets of SARS-CoV-2. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
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Since the first outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Wuhan, Hubei, China in December 2019, it is now recognized as a pandemic by the World Health Organization (WHO) as more than 200 countries and territories worldwide are affected with an increasing incidence. The SARS-CoV-2 infection results in a spectrum of non-specific signs and symptoms, ranging from asymptomatic infection, to flu-like illness such as fever, cough, dry cough and fatigue, to pneumonia, acute respiratory distress syndrome, and even multi-organ failures with high morbidity and mortality. SARS-CoV-2 is mainly transmitted through respiratory droplets that infected people exhale during incubation and onset period. By 12 June 2020, over 7.5 million confirmed cases of Coronavirus disease 2019 (COVID-19) with more than 421,000 deaths in the world have been reported to the WHO. No specific medication is approved to treat COVID-19, raising the urgent need for antiviral drug development. By 12 June 2020, there are over 1000 clinical trials registered in clinicaltrials.gov for treatment of COVID-19. This review summarizes the epidemiology, virology, clinical presentation, pathophysiology, diagnosis, and particularly the antiviral drugs currently under clinical trials for treatment of SARS-CoV-2 infection, together with the challenges and perspectives of this disease are also discussed.
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Eighteen elderly recurrent fallers and 18 elderly non-fallers were recruited from the MOBILIZE Boston Study (MBS), a population-based cohort study investigating novel risk factors for falls.
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Patient navigation to promote engagement in smoking cessation treatment was feasible and acceptable to participants.
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Are therapies for Lassa fever being developed for future use or are they still under investigation?
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iam suffred from spam muscles of bacl with pivd-l5-ls1 please tell me the treatment.please reply my problem.i have sever lower back pain n also loss of normal lordotic curvature of l/s spine with straightening of spine
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HELLO SIR, DOCTOR HAD SUGGESTED ME YOUR CREAM FOR USING IT ON DARK CIRCLES i.e(depiwhite under eye gel) BUT DUE TO CERTAIN MISTAKE CHEMIST HAD GIVEN ME DEPIWHITE CREAM..I HAD APPILIED IT ON MY DARK CIRCLES FOR DAYS REGULARLY WHICH HAD CAUSED A REACTION (REDNESS ON DARK CIRCLES,IRRITATION )AND WHEN I HAD SHOWN IT TO MY DOCTOR HE SAID TO USE DEPIWHITE UNDER EYE GEL .. BUT THERE ARE SOME FOLLOWING QUERIES WHICH ARE AS FOLLOWS 1 IS IT A REACTION ? 2 IF IT IS A REACTION HOW MUCH TIME IT WILL TAKE IT TO OVERCOME ? 3 FROM WHEN TO APPLY DEPIWHITE UNDER EYE GEL AFTER REACTION IS TREATED OR I CAN APPLY IT ON THAT REDNESS PART OF DARK CIRCLES.
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Since December 2019, the five continents have been incrementally invaded by SARS-CoV-2. Africa is the last and least affected to date. However, Algeria is among the first countries affected since February 25, 2020. In order to benefit from its experience in the least affected countries, this study aims to describe the current situation of the epidemic and then retrospectively estimate its real burden. As a first part of the study, we described the indicators of the epidemic as; the cumulative and daily reported cases and deaths, and we computed the R0 evolution. Secondly, we used the New York City cases-fatality rate standardized by Algerian age structure, to retrospectively estimate the actual burden. We found that reported cases are in a clear diminution, but, the epidemic epicentre is moving from Blida to other cities. We noted a clear peak in daily cases-fatality from March 30, to April 17, 2020, Fig. 3, due to underestimating the actual infections of the first 25 days. Since May 8, 2020, the daily R0 is around one, Fig. 4. Moreover, we noticed 31% reduction of its mean value from 1,41 to 0,97 between the last two months. The Algerian Age-Standardized Infection Fatality Rate we found is 0,88%. Based on that, we demonstrated that only 1,5% of actual infections were detected and reported before March 30, and 20% after March 31, Fig. 5. Therefore, the actual infections burden is currently five times higher than reported. At the end, we found that at least 0,2 % of the population have been infected until May 27. Consequently, the acquired herd immunity to date is therefore not sufficient to avoid a second wave. We believe that, the under estimation of the actual burden of the epidemic is probably due to the lack of testing capacities, however, all the indicators show that the situation is currently controlled. This requires more vigilance for the next weeks during the gradual easing of the preventive measures.
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Hello doctor, My fiancee and I had unprotected sex a few days back, but I did not ejaculate inside her. Just to be on the safer side, we wanted to use the emergency contraceptive pill. But due to some restriction in the country where we live, Plan B or emergency contraceptive pills are not available. I read that Yasmin, which is used as a regular contraceptive pill can be used as an emergency contraceptive pill at a higher dosage. Can Yasmin be used as an emergency contraceptive pill? And at what dosage?
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Hi Doctor, would it be possible to have allergies on shampoo? Been using this brand before and I just stopped because I tried on a new brand and then I went back again to use the same brand. Then it sort of my scalp is starting to itch and I can feel itchiness all over my body. But I have no rashes or anything. Just weird itch all over. Can I take celestamine for it and how for long? Thanks
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Hi, I recently had two gold crowns put onto two of my right lower molars, however it has been two wks and I am stii have sensivity to cold and a bit of tenderness to a stong bite when I chew on that side of my mought. My dentist told me that my teeth did not need a root canal and the caps were put on pefectly and that I should give my tooth some time to settle and adjust the crown. I have had crowns done b4 and this did not happen and I am worried that something is wrong and the crowns will have to removed and re installed to fix what is wrong but my dentist thinks that in time it would be okay with soem prescription strenght floride toothpaste but I do not know what to believe or do.
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Hi ,I am 25 years old.I have suffered night fall nearly 1000 days .and have masturbate only 5-6 times till date.My skins are not moisturized as it should be given my age and my skin is not so thick now .Is it the reason for all those night falls.Please answer
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Hello doctor, I have been experiencing pain around the bone of the little finger. It is just below the end of the finger, near the joint of the bone joining the palm. I did an X-ray and no crack was shown. I play cricket. So, I experienced this after taking a catch two months ago. It pains every time I take a catch, and me being an import and fielder, I cannot evade fielding. I took six weeks of rest, and still experienced the same pain. I took pain killers and even applied some gel, but nothing has helped so far.
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I am recovering from a fairly serious cellulitis infection for which I was hospitalized. When I was running fever I felt alot of tightness in my chest. No more fever, but I still feel the tightness even while resting. My heart seems to beat rather strongly when I move around. I have mild asthma and take medicine for that so my breathing is fine.My question is: is it normal to feel this when fighting a severe infection?
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hi sir. gd evng. i hv a query!!! for burns treatment ( my son has got his skin burnt with the silencer of the bike ) whether silverex ointment is better or silverex nitrate gel 0.2 %( he has open wound, skin completely removed from tht site ). wt is the difference of these two applicants?
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Hello doctor, I have uneven skin complexion and dark skin. Can you please tell me any cream or foods that improve my skin and skin color?
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The devastating and disproportionate toll of the COVID-19 pandemic on communities of color has drawn attention to longstanding disparities, traceable to systemic factors that result in structural trauma. As a medical specialty, psychiatry has begun to grapple with its own history of institutional racism, with calls for a multifaceted approach to proactively address upstream institutional factors that inflict structural trauma. Psychiatric clinician leaders can play important roles in addressing these factors. This work can occur through the individual psychiatrist's targeted exertion of facets of the clinician leader role. Here, we consider a previously described clinician leadership model (the Four Factor Model) through the lens of structural inequity. We link this model to the real-world example of the city of Philadelphia's efforts to address mental health inequities, demonstrating the application of different facets of the psychiatrist's leadership to address structural trauma in the context of local government. [Psychiatr Ann. 2021;51(11):522–527.]
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What exactly is Omega-3 and to what does it refer?
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I have a small lump on the right side of my temple. It almost feels like the vein is sore and alightly swollen. My left temple is sore also, but there is no swelling. I have not hit my head recently. The discomfort has been going on for about four days.Do you have any idea what this could be?
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Hello Dr. good after noon. I am Rajendra Gupta from India. 62 yrs. Under went bypass surgery in March 1999. Keeping stable since than. Suffering from Psoriasis since last 35 years. Present problem is Joint pain. Several Blood tests performed and found within normal range. My e-mail is YYYY@YYYY
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Hi! Happy new year to all doctors.My problem is I was alright 15days before then I had fever for 1day, followed by cough and greenish expectoration.I had levofloxacine 500mg for 5days with Brozedex cough syrup.Sputum became watery and scanty and cough persisted without fever. I had cetrizine and syrup dextromethorphan & tripolidine. Cough with little watery sputum persisted.Then I had cefixime 200mg bid 5days.But symptoms not resolved.Please give me your expert advice. Thank you.
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What is the recommended management approach for small bowel obstruction caused by herniation with signs of bowel ischemia?
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My Father has advanced Cirrhosis and from the description of symptoms he also has HE. He is a big guy - 200lbs 6 and he is shouting and confused, hallucinating vividly, trying to get up from bed, angry, his hands, legs and feet shake. He has moments of lucidity. After eating just a few bites of food for 8 days he gorged on food yesterday and couldn t get enough. He has constant mood swings. He is going into a Hospice facility today, but we are worried he will be too much for the staff to handle the way he is. Is there any guideline for how long someone can experience these severe symptoms of HE before ammonia levels increase and he goes into a coma?
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sir my recent 2d echo report shows that there is mild concetric LVH am suffering from bp and troubling with breath less ness in 2009 angiogram was done .it reveals that no blocks mild cad with ectic coronaries am a heavy smoker .sir how to get rid of brethlessness
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I am taking two Curcumin tabs per day for osteoarthritis of the hips. I have been on them for about two weeks. I also take 4 panadol osteos, 7mls olive leaf extract, cerc, macuvision, lutein defence, COQ10, promensil, Metamucil, calcium, D3, B12. I have had a slight tremor in my left hand for about two years, in the last two weeks it has worsened and also has started in my left leg and right hand. Fine motor skills are slightly affected. I have a herniated disk between 5th and 6th vertebrae. The cardiologist is investigating heart arythmia. He has sent me for a thyroid test. I am on a very healthy diet but have started eating about 4 pieces of 70% cocoa dark chocolate daily. I am wondering if any of the above is leading to the tremors. I am 66. Robyn
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These study results support growing evidence that meaningful changes have occurred over the last 3 years in how anemia is clinically managed in US hemodialysis patients.
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I had a ddogs teeth scrape about 1/4 deep into my arm and now the area around and where the scraping happened is swollen and numb on the surface, under it is not but as deep as the scrapes go as well as the area around it are numb, what is causing that
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My wife 61 years has received brain radiation therapy (15 sessions) for suspected solitary cancer lesion detected 15 days after left breast surgery for removal of lump.She has disturbed gait despite brain radiation therapy which was completed 5 days ago. Please advise as to when normal gait would be restored. What further treatment may be required.At present she is taking 4 mg. dexan BD.
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The host cell receptors and associated anti-viral genes mediating SARS-CoV-2 infections are still elusive Here, we show that COVID-19 patients compared with he
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They say all my pains are coming from my back problem .I don t think so I hurt in my hips in the morning I can,t even stand up at frist from hurting in my hip joint. I know my back give me problem s but now I ,m beginning to hurt all over. and night time is the wrose. I can t sleep. and it feels like all my inter bones hurt so.
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hi my baby is 2 months and 3 weeks old she only breastfeeds, but when i try to feed her she won t latch on and cries like crazy.I keep trying but she just cries everytime. I know it s not my milk cuz when i pump she drinks it from the bottle. can you please help me. Also she has no allergies and is a healthy baby.
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my husband had a triple heart by pass two years ago this month. Successful and quick recovery. He is 74 but has had a chronic hacking cough that has persisted since and now is much worse. His check ups have appeared to be good and the Dr thought maybe it was due to allergies? It has become almost constant clearing of throat and now coughing is much worse..
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Hello, I am experiencing muscle cramps, runny nose, diarrhea, headache, cough (worse at night), nausea, sore throat, and earache. I'm not sure if its just a common cold or if it is something viral. I went to the doctor 5/2/17 and I was told it was just a cold. They wanted to place me on steroids however my physicians at John Hopkins didn't approved the steroids and told me not to take that prescription due to other medical history.I believe I may also have bacteria vaginosis, I'm not sure if that could be related at all however I do feel miserable. If you have any advice please let me know.
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In the event of an overwhelming influenza pandemic, many health care systems will implement a triage system that would potentially deny critical care treatment to some seriously ill patients. Although all triage systems have guaranteed palliative care for those who are denied critical care, no jurisdiction has yet developed a plan to accommodate the anticipated “surge” in demand for palliative care. The authors present a mathematical and ethical justification for a palliative care surge plan and outline some of the key elements that should be included in such a plan.
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Fell off ladder and fell backwards on tailbone. It happened at work 12 days ago and I still feel a lot of pain. Rectum area sore also. No bleeding. Does it take a long time to heal? I am still working and on my feet all day. Could that be delaying the healing process? Standing up and laying down is not as painful as when I am sitting and compressing the area.
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Doctor my daughter is eight months old and has recently picked up a bad cough when we traveled home to the UK, we are currently living in Cairo and are unsure of what type of medicine would best treat her cough, she is also teething is there a link between the two.Should she take a anti biotic shot?
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My husband was diagnosed with asthma earlier this year having suffered an attack in the spring. He had another session before xmas which lasted well over 2 weeks. Went to a walk-in clinic 2x within a week as his symptoms were severe. Prescribed steroid drugs in conjunction with regular puffers. He started doing some light cardio within the past several days and felt stronger, although his airways still feel somewhat constricted. He played hockey tonite (taking it easy according to him) and immediately felt extremely dizzy when he got off the ice. The dizziness has continued, so far 3 hours since he played. Im concerned if he should seek immediate help or can he wait to see if the dizziness settles down. His doctor is away until next Tuesday. Thank you very much.
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Q:A 34-year-old woman with a history of depression is brought to the emergency department by her husband 45 minutes after ingesting an unknown amount of a termite poison in a suicide attempt. She has abdominal pain, nausea, and vomiting. Her husband reports that she has had two episodes of watery diarrhea on the way to the emergency department. A distinct, garlic-like odor on the breath is noted on examination. An ECG shows sinus tachycardia and QTc prolongation. Administration of which of the following is most appropriate?? {'A': 'N-acetylcysteine', 'B': 'Fomepizole', 'C': 'Deferoxamine', 'D': 'Physostigmine', 'E': 'Dimercaprol'},
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Hi Doc,Am a Throat Cancer Patient since 2008. Since then i have undergone about half a dozen Radio-Iodine Therapies - High Dose.After a Year of Disease Free Session I had a relapse. My Current Doc is in Pune, India and would like to get 2-3 other Opinions. Please advise.Thank you Asang
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I have noticed that both my testicles are not as spongy feeling as they used to be. They seem kind of hard and maybe a little larger than they used to be, but they feel smooth with no noticeable bumps. I am 35 is normal or something I should worry about?
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Hi, may I answer your healim 18, male , and black... Ive been having chest pains for a few years now, And recently theres been other syptoms along with it. Such as tingling feelings threw my body.... Mainly the left side, and shortness of breath, also like a jerk feeling in my chest that happens nnot so often but happens while my heart beats.. I also have been feeling light headed , and cant get no rest at night... ive been to emergency rooms and have had ekgs and chest x rays and they tell me everything is normal... but the syptoms have increased at a fast rate and its really making start to doubt that there missing something they should not be... and this is really starting to scare me.... please help me!!!th queries right now ? Please type your query here...
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I had breathed the smoke from the plastic burning for about 15 minutes and tried i know that i could not stand all kind of smoke and i tried to get out from there and after that i had found that i cannot breathe easily, I feel like my chest is very heavy and i still do now. How can i solve this ? do i need to eat something or go to see the doctor? I am 20 years old, weight 48 and 160 height
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Efforts to improve long-term outcomes of older patients with major depression and/or dysthymia should focus on providing more intensive treatment and follow up for patients with residual depressive symptoms.
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What is primary hyperaldosteronism, and what are two potential causes of this condition?
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Q:A 17-year-old high school student comes to the physician because of a 6-month history of insomnia. On school nights, he goes to bed around 11 p.m. but has had persistent problems falling asleep and instead studies at his desk until he feels sleepy around 2 a.m. He does not wake up in the middle of the night. He is worried that he does not get enough sleep. He has significant difficulties waking up on weekdays and has repeatedly been late to school. At school, he experiences daytime sleepiness and drinks 1–2 cups of coffee in the mornings. He tries to avoid daytime naps. On the weekends, he goes to bed around 2 a.m. and sleeps in until 10 a.m., after which he feels rested. He has no history of severe illness and does not take medication. Which of the following most likely explains this patient's sleep disorder?? {'A': 'Delayed sleep-wake disorder', 'B': 'Psychophysiologic insomnia', 'C': 'Advanced sleep-wake disorder', 'D': 'Irregular sleep-wake disorder', 'E': 'Inadequate sleep hygiene'},
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I have several freckled colored spots on my body. They started on my chest, then disappeared and moved to my neck. After those disappeared they moved to the top of my thigh and they just keep disappearing and moving. They itch like crazy. My whole body has been itching like crazy. I don t know what it is and its been here for like a month now.
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Hi I am 43 year man and i suffering from chest pain from last 2 years. I have done cardiography before 6 months but there was no problem reported but i still have chest pain and some time i feel fine. So pls suggest me what can i do Thanking you
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Q:Three weeks ago a 45-year-old man was admitted to the hospital because of frostbite of both feet. He was treated by rapid rewarming and protective care of the feet. All the toes on the right foot have turned black. He has become slightly febrile and progressively more confused during the past few days. Examination discloses cellulitis in the midfoot. Which of the following is the most appropriate treatment?? A:Amputation;B:Application of topical collagenase;C:Debridement of necrotic skin over the toes;D:Hyperbaric oxygen
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What causes St. Louis encephalitis?
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I have 2 lumps on my body that are thought to be boils, i have one on my wrist and one under my armpit, I'm guessing that i am spreading them from place to place. I have been put on anti-biotics and the boils seem to go down but then after about an hour they come back worse and much more painful. Help!
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Hello, please my friend av been sleeping with 2 guys, she use postinor2 after sex with first guy after sex and does not take postinor2 after sex with the other guy bcos he his her husband, wen she is pregnant ,is it the guy or the husband that impregnated her, Pls reply
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hi! my child has i think develop his vomiting habit. he throws up anytime of the day, cases like, when he cries, sees food (fave food), when he is afraid of something, or for any other reasons which i really dont know. how can i help him overcome this one? pls, i need your advice....thank you - adigg
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The study explores older people's perceptions and experiences with mobile technology adoption in hospitals. Twenty nine older people were interviewed at a tertiary hospital in Guangzhou from June to December 2020. All the interviews were analyzed using thematic analysis. Older people are a diversified group. Various factors impact their readiness for technology use, including their educational level, age, past experiences, living arrangements, etc. The older people in this study in general expressed a great concern about using the new health technology and many encountered barriers to its successful adoption. Yet, the barriers and difficulties that they encountered are embedded in a changed social context in China. The findings above provide insights into the adoption of health technology, and tailored measures to facilitate older people's technology adoption are suggested.
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My name is Muhammad Asif. My sister is facing serious pregnancy issue. She has lost her two child in previous cases. Now again she is pregnant and after 5th month doctors are saying that the growth of child is abnormal again. I have her reports and i want to take opinion on that. Please help. Thanks alot
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I'm a follicular lymphoma patient, currently doing the Rituxan maintenance program at the one-year point. Just now noticing some bruising at my lower spine and the neck, seeming only from stretching moves at yoga. Now I have also developed some large cyst-like lumps supraclavicular (Rt) with a thickening over the sternum and a lump creeping up the base of my neck (rt side). My doc is getting ultrasound done and asking my hematologist to review. Might it be cardiovascular instead - blood clots? My platelets and white blood cells have recently dropped, first time, to the lower end of 'normal range'. I'm concnered what this means...
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I have two hard lumps that are almost in the same area under my chin on both sides. I have had them for a few years. When they first appeared I was told that they were due to an abcess. The lumps never went away. I am able to move them a bit but they have never caused any discomfort. Three days ago I had a root canal done on the tooth . The lump on the side where the root canal was done has gotten larger and hurts. I am really worried that the lump has grown in size. Whenever I have asked my dentist about it I was always told that it formed as a result of the abcess...but shouldn t that have gone away? I m just worried that it may be cancerous and have been given the wrong advice all these years! Please help!
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Im 21years 8months of old. recently because of excessive pain i got u/s for scortum and im diagnosed with bilateral Grade 1 varicocele and epididmyal cyst on the right testis.im having pain or discomfort from past one year. please teme the best solution possible, because Im afraid of ma on coming marriage life
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Abstract Home care services are an alternative answer to hospitalization, and play an important role in reducing the healthcare costs for governments and healthcare practitioners. To find a valid plan for these services, an optimization problem called the home healthcare routing and scheduling problem is motivated to perform the logistics of the home care services. Although most studies mainly focus on minimizing the total cost of logistics activities, no study, as far as we know, has treated the patients’ satisfaction as an objective function under uncertainty. To make this problem more practical, this study proposes a bi-objective optimization methodology to model a multi-period and multi-depot home healthcare routing and scheduling problem in a fuzzy environment. With regards to a group of uncertain parameters such as the time of travel and services as well as patients’ satisfaction, a fuzzy approach named as the Jimenez’s method, is also utilized. To address the proposed home healthcare problem, new and well-established metaheuristics are obtained. Although the social engineering optimizer (SEO) has been applied to several optimization problems, it has not yet been applied in the healthcare routing and scheduling area. Another innovation is to develop a new modified multi-objective version of SEO by using an adaptive memory strategy, so-called AMSEO. Finally, a comprehensive discussion is provided by comparing the algorithms based on multi-objective metrics and sensitivity analyses. The practicality and efficiency of the AMSEO in this context lends weight to the development and application of the approach more broadly.
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i have a regular pain in left lower abdomen.i consult docter she advise me to a utrasound.in ultrasound report 3 mm calculus is found in both kidneys.but i have no pain in right side.i take treatment for two months but no relief in left side .then doc advise me to get another ultrasound.the report i.s like this.....................KIDNEYS-THERE ARE SMALL CALCULUS 3 MM IN SIZE.CORTICOMEDULLARY DIFFERENTIATION IS WELL VISUALIZED IN LEFT KIDNEY.NO EVIDENSE OF OF ANY HYDRONEFROSIS SEEN..............................OVERY---right ovary is 3.4 into2.3 in size with few small follicles and raptured follicles....................left ovary is 2.8into2.1cm in size with few small folicles.........................no mass lesion or fluid is seen in the pelvis ........IMPRESSION-----FUC of bilateral small renal calculi......... pleas tell me what does it means ?as i have a regular pain in lower abdoman and sometimes it creats a lot of pain
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OBJECTIVE: The pandemic coronavirus disease-19 (COVID-19) has pushed the global healthcare system to a crisis and amounted to a huge economic burden. Different drugs for prophylaxis against COVID-19 including chloroquine (CQ) or hydroxychloroquine (HCQ) have been tried. This study was performed to systematically review the role of CQ and HCQ in preventing the spread of COVID-19. METHODS: PubMed, EMBASE, ClinicalTrials.gov, International Clinical Trials Registry Platform and Cochrane Library databases were searched for studies that evaluated the prophylactic role of CQ or HCQ on SARS-CoV-2 (pre-clinical studies) or COVID-19 (clinical studies) until 30 March 2020. The available literature was critically appraised. RESULTS: A total of 45 articles were screened and 5 (3 in vitro pre-clinical studies and 2 clinical opinions) were included. The pre-clinical studies showed the prophylactic effects of CQ and HCQ against SARS-CoV-2. On the other hand, the clinical opinions advocated the prophylactic use of CQ and HCQ against COVID-19. However, no original clinical studies on the prophylactic role of CQ or HCQ on COVID-19 were available. CONCLUSION: Although pre-clinical results are promising, to date there is a dearth of evidence to support the efficacy of CQ or HCQ in preventing COVID-19. Considering potential safety issues and the likelihood of imparting a false sense of security, prophylaxis with CQ or HCQ against COVID-19 needs to be thoroughly evaluated in observational studies or high-quality randomized controlled studies.
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my wife has had a bad back for 3 years now and it gets very painful she has been diagnosed with a pertruding disc and now the spine is bone on bone she is on atasol 30s and muscle relaxers since yesterday she has been complaining about pain under her lower right rib and she cant bairly move thought this was free SORRY DONT HAVE A CREDIT CARD
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A 5 6 , 210 lb., 64-year-old male business executive had a physical exam prior to his retirement from corporate work. His blood pressure was 180/115 on three separate days. Further examination showed normal to low plasma renin activity, elevated total peripheral resistance (TPR), cardiac output (CO) of 7.2 L/min, x-ray evidence of left ventricular hypertrophy, retinal hemorrhages, and mild polyuria. Recommended therapy was weight reduction to his ideal level, a low-salt diet (1. What is the diagnosis for this individual? 2. What should this individual s ideal body weight be? (Assume he is of medium body frame.) 3. Explain the sites of action for the three pharmacologic agents prescribed for this individual. Oral diuretic: Beta-blocker: Vasodilator: 4. Why was the vasodilator not used before the other drugs were added? 5. Outline the usual steps in the medical treatment of hypertension. 6. What was the cause of the retinal hemorrhages? 7. Define and indicate the causes of the cardiac hypertrophy and polyuria. 8. Write the formulas for determining mean arterial blood pressure, blood pressure, and pulse pressure. MABP = BP = PP =
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What are the recommended treatments for Parvovirus B19 in immunocompromised patients?
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Hi, I'm a 48 yr old female and I have been experiencing pain on and off in the center of my chest and it can sometimes hurt around my left shoulder blade area. I have been to the Dr many times, the Gastro Dr did a scope test and had a stress test done in the last 2 to 3 years. The Dr did EKG's - normal. The Gastro Dr said that I had mild to moderate reflux and gave me protonix 2x's a day and omneprozole(sp?) at night. I also passed the stress test and was told everything was fine. I take medicines for allergies, borderline BP and Cholesterol. I have been doing fine the last few months but last night the pain came back. It is worse when I sit down. I told my Dr that I thought the meds I take is causing constipation, I have this problem alot. Could this be causing my pain?
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Catabolic conditions, such as starvation, inactivity, and cancer cachexia, induce Forkhead box O (FOXO) transcription factor(s) expression and severe muscle atrophy via the induction of ubiquitin-proteasome system-mediated muscle proteolysis, resulting in frailty and poor quality of life. Although FOXOs are clearly essential for the induction of muscle atrophy, it is unclear whether there are other factors involved in the FOXO-mediated transcriptional regulation. As such, we identified FOXO-CCAAT/enhancer-binding protein δ (C/EBPδ) signaling pathway as a novel proteolytic pathway. By comparing the gene expression profiles of FOXO1-transgenic (gain-of-function model) and FOXO1,3a,4-/- (loss-of-function model) mice, we identified several novel FOXO1-target genes in skeletal muscle including Redd1, Sestrin1, Castor2, Chac1, Depp1, Lat3, as well as C/EBPδ. During starvation, C/EBPδ abundance was increased in a FOXOs-dependent manner. Notably, knockdown of C/EBPδ prevented the induction of the ubiquitin-proteasome system and decrease of myofibers in FOXO1-activated myotubes. Conversely, C/EBPδ overexpression in primary myotubes induced myotube atrophy. Furthermore, we demonstrated that FOXO1 enhances the promoter activity of target genes in cooperation with C/EBPδ and ATF4. This research comprehensively identifies novel FOXO1 target genes in skeletal muscle and clarifies the pathophysiological role of FOXO1, a master regulator of skeletal muscle atrophy.
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My fatheraged 75+ is daibetic since last 10 + years, although his sugar level is well in control. He takes glynase tablet. Since last few dayz his BP started to climb and reached as high as 180/100. We suggested a doctor, he started Remistar and 2 other medicines whose commercial names are Eslo and GLA. After taking this prescription his BP lowered and reached around 140/80, but he has continuous headache that too very severe. Plz advise me what to do?
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Hello doctor, My fiancee and I had unprotected sex a few days back, but I did not ejaculate inside her. Just to be on the safer side, we wanted to use the emergency contraceptive pill. But due to some restriction in the country where we live, Plan B or emergency contraceptive pills are not available. I read that Yasmin, which is used as a regular contraceptive pill can be used as an emergency contraceptive pill at a higher dosage. Can Yasmin be used as an emergency contraceptive pill? And at what dosage?
urgent
Okay so recently when I stand up I get a rush of black spots like most people do, but whenever I try to shake it off my knees will starts to get weak. It feels as if my whole body is having a spasm, because my body moves back and forth. I have fallen to the floor when this happens, now I usually try to lay down and close my eyes and wait for it to pass. Could you tell me why my body is doing this?
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INTRODUCTION: The outbreak of the COVID-19 has largely impacted individuals’ health and lifestyles. This study aimed to investigate people’s psychological well-being during the second phase of the COVID-19 pandemic. METHODS: We selected six indicators of psychological well-being: fear of COVID-19, loneliness, social interaction anxiety, generalized anxiety, PTSD, and depression. A sample of 231 Italian participants (56.3% women), with a mean age of 32.7 (SD=12.61), completed an online survey from February to March 2021, during the so called “second wave”. It included the Fear of COVID-19 Scale (FCV-19S), the UCLA Loneliness Scale- Version 3, the Generalized Anxiety Disorder 7-item Scale (GAD-7), the Patient Health Questionnaire-9 (PHQ-9), the Impact of Event Scale–Revised (IES-R), and the Social Interaction Anxiety Scale (SIAS). RESULTS: Apart from loneliness, women reported lower levels of psychological well-being than men. Fairly good associations between all the detected variables were found. Based on a mediation model evaluation (in which generalized anxiety was introduced as a mediator in the relationship between fear of COVID-19, PTSD, loneliness, social interaction anxiety, and depression), except for social interaction anxiety, total and partial mediation effects suggested that generalized anxiety played a crucial role in exacerbating depressive symptoms during the pandemic. CONCLUSION: Our outcomes may expand the knowledge about the psychological well-being during the pandemic experience, with a focus on the mediating role of generalized anxiety.
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please help. I had wisdom teeth distraction and now I have bone issue that I am getting second opinion on but I have this constant salty taste in my mouth and watering my question is tr. Nueralsia something that can cause salty taste and mouth watering or not really. My dentist cannot tell if I am having this because of the bone that is healing or if I have the jaw neuralgia. Im sorry I dont know the name.
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a couple weeks ago i was having terrible pain in my back gums on my molar.i treated it with warm salt water, its healed last night i was eating and i bit my fork with my front tooth and this morning the gum behind and around my tooth is swollen and hurts.it looks like a bruise but now has a swollen lump my tooth looks crooked now .its throbbing and itchy feeling. i gargled with warm salt water and have been sipping on warm water with apple cider vinegar sweetened with raw honey i have noticed the pain and swelling are going down its still itchy but now i am able to apply pressure with my tongue .but there is a strange itchy mild pain still.why? and is there a more way to possibly treat insted of going to the dentist which i cant afford...have you heard about applying myrrh oil ?
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why do my bottom lip go numb for a few weeks my bottom lip on the right hand side and the bit under my lip has been tingling and going numb . I ve previously had cold sores there in the past and am prone to them . I m twenty eight and female. I ve been having cold sores every couple of months since roughly age fourteen. I m worried as to what this could be ??
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When to seek urgent medical care when I have Abdominal mass ?
urgent
hi, doctor, i am having epididymitis on right testicle n havin uncomfortable pain in lower abdomen... had banocide forte for more than 3 months n doxycycline for 2 months but got no result... instead pain in abdomen had become slight more occurent..
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Social media sites, which became central to our everyday lives, enable users to freely express their opinions, feelings, and ideas due to a certain level of depersonalization and anonymity they provide. If there is no control, these platforms may be used to propagate hate speech. In fact, in recent years, hate speech has increased on social media. Therefore, there is a need to monitor and prevent hate speech on these platforms. However, manual control is not feasible due to the high traffic of content production on social media sites. Moreover, the language used and the length of the messages provide a challenge when using classical machine learning approaches as prediction methods. This paper presents a genetic programming (GP) model for detecting hate speech where each chromosome represents a classifier employing a universal sentence encoder as a feature. A novel mutation technique that affects only the feature values in combination with the standard one-point mutation technique improved the performance of the GP model by enriching the offspring pool with alternative solutions. The proposed GP model outperformed all state-of-the-art systems for the four publicly available hate speech datasets.
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"The insulin adjustments are much larger than common recommendations."
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Hi Dr, I have a strange unbalanced feeling when standing, sitting and laying, as well as a strange sensation down my right, a feeling of weekness and as though it isnt connected. this feeling has been lasting for around 3/4 weeks now with varying degrees
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I have been experiencing shortness of breath and chest pain recently and I was hoping that you could help me decide if I needed to go see my doctor? I am 19 years old have never had a history of asthma and am acclimated to my altitude. I recently had a slight cold but have recovered from that almost a week ago. I have been experiencing this shortness of breath for almost 2 weeks it is extremely uncomfortable and I am winded after walking about 10 steps, additionally it is hard to fall asleep and I wheeze constantly.
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What is the relationship between bladder outlet obstruction and incontinence, and which type of incontinence is commonly associated with this condition?
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Hi doctor, I am a 67 year old male. I am overweight, mildly diabetic and have high BP. I have pain on backside of my left heel. It increases in the evening. I think I have Achilles tendinitis. Please help.
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Hi my son is 1.7 yrs he as loose motions not very liquid it thicker and its completely green in color and its almost a 10 days now. Went to doc for consultation but still the same e was under Flagyl suspension and Gramogyl syrup. Is der anything else can be done. Pls advise
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Although Models 2 and 3 reached similar shared variance (∼55%), more LOS variables predicted DHI, showing that this test is more broadly related to subjective symptoms than SOT, which showed only one predictive variable.
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A few months ago I had a pain attack in my lower right abdomen, it was umbearable... drs couldnt even apply any pressure to the area without me screaming in pain, i went to hospital the got rushed to another hospital as the thought it was accute apendicitis. I was given morphine and after about 2 hours the pain went away completly. Ever since this attack i have had many small bouts of pain in the same are... no where near as bad but uncomfortable, along with the pain it also feels like there is some preasure in the area aswell. 2 GPs i have seen have just said to take pain releif and rest, without doing any tests... should I be concerned.?
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I just accidentally swallowed part of a scone the wrong way and started coughing it up. I heard that if you don t get it all out, you can get pneumonia. This happened roughly 20 minutes ago and I now have chest pains and am still coughing some. Am I ok?
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The results of our study confirm a substantial variation in the cardiac venous anatomy.
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I was doing a Barre workout this morning (a plie in horse pose or 2nd position) and the inside of my knee, just inside/under the knee cap popped. The pop was on the down/plie move. Very unusual for me...I could keep going but had to adjust - if my foot was strait on it was better. But now as the day moved on, there is pain on the outside of my knee as well. So though you can t look at my knee and see swelling, because the pain is increasing somewhat, I know there is swelling. I have taken Advil. Just wondering if I should give it a few days or go have it checked.
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Hi.. there was a upper esophageal Tumor in throat..operated during that..the food pipe got rotten and dr.cut the rotten part and joined the rest Food pipe with stomachafter few days of this operation there was a pinhole linkage though afterwards treated by dr ..but by that food pipe got shrinked.and intake of any liquid is stopped.so please suggest the further treatment for curing shrinked Food pipe.. so that the patient can intake some thing
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What distinguishes poxviruses from other DNA viruses in terms of their shape?
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I have a query related tooth decay.I saw black colour on my teeth then I went for treatment and then at the time of drilling for filling bleeding started. then she said I have to go for RCT. she just did temporary filling there then I thought to consult another doctor then he said wait for 1.5 month ,if no pain persist then come they will go for permanent filling I went there after 1.5 month and having no pain so they did permanent filling,after 4 days of permanent filling I am just seeing that my tooth colour is again changing to black and iI feel pain during chewing the food.
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