UniProt ID
stringlengths 6
10
| Protein Sequence
stringlengths 2
35.2k
| Functional Description
stringlengths 5
30.7k
|
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Q07263
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MARRSRLRRLLLLLLLPVASTSDAEHRLFERLFEDYNEIIRPVANVSDPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYDGAEFMRVPAEKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPAWVKTIFLNLLPRVMFMTRPASNEGNTQRPRPFYSAELSNLNCFSRIESKVCKEGYPCQDGLCGYCHHRRAKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLMTRDDA
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After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. Interacts with LYPD6. The heteropentamer alpha-3-beta-2 interacts with alpha-conotoxins ImI, ImII, PnIA, GID and MII. The heteropentamer composed of alpha-3 and beta-4 subunits interacts with the alpha-conotoxin ImI. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
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P18845
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MNSASRITLFFLLTVLITQECLSSKGEDRLFRRLFRRYNQFIRPVENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLKWLPAEFDGIEFIRVPSNKIWRPDIVLYNNAVGDFLVEDKTKALLKYDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDLVLIGSKVNLKDFWESGEWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTILVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHTMPSWVRTVFLRALPRVMLMRRPIDLSESSGKGGGEIAGSSGTGGGRGAEGKKMKSSASQQGAMNSLEFGEGKAALEGKKGGCPCHPIKEAIEGDCGKVSRQLTPQAINTVVTFSVVSPEIKQAIESVKYIAENMRSRNKAKEVEDDWKYVAMVIDRIFLWVFVLVCVLGTLGLFLQPLIGFFS
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After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR seems to be composed of two different type of subunits: alpha and non-alpha (beta). Expressed in retina and brain. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
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P09481
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MQSIHALLLTAAVCILFQGCGGSEPEHRLYAALFKNYNQFVRPVKNASDPVIIQFEVSMSQLVKVDEVNQIMETNLWLKHIWNDYKLRWNPVDYGGAEFIRVPSGQIWKPDIVLYNNAVGDFQVDDKTKALLKYTGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSTMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPVWVRTIFLNLLPRIMFMTRPTSDEENNQKPKPFYTSEFSNLNCFNSSEIKCCKDGFVCQDMACSCCQYQRMKFSDFSGNLTRSSSSESVDPLFSFSVLSPEMRDAIESVKYIAENMKMQNEAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLMTGDDM
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After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR seems to be composed of two different type of subunits: alpha and non-alpha (also called beta). A functional receptor seems to consist of two alpha-chains and three non-alpha chains. High levels in the developing ciliary and superior cervical ganglia. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
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Q5DZD2
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MNNEYVLVINSGSSSLKFAVIDSVSGDAVLSGLGECFGLEDARMSWKYQGQKTEIAIEGNENHHKIAIGKLVGLTEELGFTDGIVAIGHRIVHGGEKFTKTVRINEEVTKEIESLSDLAPLHNPAGAIGIRAAVEAFPSLPQFAVFDTAFHQTMPKRAYTGAIAKELYTDFGVRRYGFHGTSHYFVSREAAKMINKPIEESNFISVHLGNGASVCAIKDGNSVDTSMGFTPLSGLMMGTRCGDLDPGIIEYLLKKGWSQEQVFNSLNKESGFLGVSGLTSDARGILEAMEEGHEGATLAFQVFTYRVAKYVASYLAALDSLDGIIFTGGIGENSLPIRREILSNLKILGFVEDVAGNEGARFGADGIIAKSEMLNAVAMVIPTNEEFVIAQQSVELL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q8XJN2
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MNVLVINCGSSSLKYQLIDMDTENALATGLVERIGLEGANLTQKSEGKDKYEIVEPMKDHQDAIRLVLGALIDEKHGVIKSLDEINAIGHRVVHGGEKYAESALVTEEVMKDLEECAKLAPLHNPANIIGINACKALMPNVPMVVVFDTAFHQTMPEKAFVYALPYELYEKEHIRKYGFHGTSHKYVSAKIAEAMGKNIEDLKIITCHLGNGASIAAIKNGKCVDTTMGFTPLEGLVMGTRCGNIDPAVVTYLIDELGYTSQEVNTLMNKKSGIFGVSGVSSDFRDVEAAADKGSKEAQIALDLFRNSVKKYIGAYIAEMNGCDVIVFTAGVGENSIIERGAICRDLEFLGIELDEERNNIRAKVAEISKEGSRIKLFVVPTNEELMIAQDTVSIVSK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q9CE36
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MEKTLAVNAGSSSLKWQLYEMPEETVIAKGIFERIGLSGSISTTKFNNEEHFRKQEIVDHRQAVLLLMDELIHFKLIHEFREITGIGHRVVAGGEFFKTSTVISPEVLAEIKNLSTLAPLHNPANVLGIEAFQRLLPDALAVAVFDTAFHSTLPEKAYRYPIPTKYYEDYSIRKYGAHGTSHMYVAQEAEKVLGKPLEDLKLITAHIGNGASITAIEAGKSVDTSMGFTPLAGVMMGTRAGEMDASVIPYMLESDPSLRNAQDVIDILNKDSGVLGVSELSSDMRDLSEAVAKGNPKAILAYEMYVDRLKKFIAQYFGVLNGADALIFTAGVGENDTAVRTDVVNGLSWFGMEIDESKNVRGAFGIISKPESKVKVLVVPTNEELVIARDVEAAK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q92CN9
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MHKIMAINAGSSSLKFQIFTMPGEEVLVKGLIERIGLPDAIFNMSFQNEKIKETRAINNHGEAVEILLEQLKTHQVINDLNEITGVGHRVAHGGEAFVSSCIVTDDVVKGIEDVTSLAPLHNPANIIGIKTFRELLPNAVSVAVFDTAFHQTIPEENFLYALPYELYEKHHIRKYGFHGTSHKYVAGKAAEVLKKPLEKLKIISCHLGNGASVCAIEAGKSVNTSMGFTPNAGLMMGTRSGTIDATIIPYLVDELGYSLDEVTHMMSSESGVLGVSGISSDFRDIEIAANEGNSRALLTLRMFTGQICNYIGAYASAMNGCDALLFTAGVGENSPLIRKMVTEQLSYLGVTCNVTKNNAGDMIISNDDEAVKVCIIPTNEELMIARDVEKYTKQTIS
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q71Z86
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MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDHEIAVQMLLEKLINHKVIGSYDEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPLHNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLYSLPYSYYEDYGIRKYGFHGTSHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRSGNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELALQVFVDRIHKYIGSYAARMNGVDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVRGEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNH
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q8Y7V1
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MHKIMAINAGSSSLKFQIFTMPGEEVLVKGLIERIGLPDAIFNMSFQNEKIKETRAINDHGKAVEILLEQLKAHQVINDLSEITGVGHRVAHGGEDFVTSCVVTDEVVKGIEAVTNLAPLHNPANIIGIKTFRELLPNAVSVAVFDTAFHQTIPQENFLYALPYELYEKHHIRKYGFHGTSHKYVAGKAAEVLEKPLEKLKIISCHLGNGASVCAIEAGKSVNTSMGFTPNAGLMMGTRSGTIDATIIPYLVDELGYSLDEVMHMMSNESGVLGVSGISSDFRDIEIAAKEGNSRALLTLRMFTGQICNYIGAYASAMNGCDALLFTAGVGENSPLIRQMVTEQLSYLGVTCHVTKNNAGDMIISNDNEAVKVCIIPTNEELMIARDVEKYAKQTIG
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A1ITN6
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MSDQLILVLNCGSSSLKGAVIDRKSGSVVLSCLGERLTTPEAVITFSKDGNKRQVPLSGRNCHAGAVGMLLNELEKHELHDRIQAVGHRIAHGGEKYSESVLIDQAVMDELNACIPLAPLHNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTYAVPRELRKKYAFRRYGFHGTSMRYVAPEAACILGKPLEDIRMIIAHLGNGASITAIKNGKSVDTSMGFTPIEGLVMGTRCGDIDPGVYSYLTSHAGLDVAQVDEMLNKKSGLLGISELSNDCRTLEIAADEGHEGARLALEVMTYRLAKYIASMAVGCGGVDALVFTGGIGENSRNIRAKTVSYLDFLGLHIDTKANMEKRYGNSGIISPTDSSPAVLVVPTNEELMIACDTAELVGIL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q9K0X1
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MSDQLILVLNCGSSSLKGAVIDRKSGSVVLSCLGERLTTPEAVITFNKDGNKRQVPLSGRNCHAGAVGMLLNELEKHGLHDRIKAIGHRIAHGGEKYSESVLIDQAVMDELNACIPLAPLHNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTYAVPRELRKKYAFRRYGFHGTSMRYVAPEAARILGKPLEDIRMIIAHLGNGASITAIKNGKSVDTSMGFTPIEGLVMGTRCGDIDPGVYSYLTSHAGMDVAQVDEMLNKKSGLLGISELSNDCRTLEIAADEGHEGARLALEVMTYRLAKYIASMAVGCGGVDALVFTGGIGENSRNIRAKTVSYLDFLGLHIDTKANMEKRYGNSGIISPTDSSPAVLVVPTNEELMIACDTAELAGIL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q6LLD4
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MSNSLVLVINSGSSSLKFALIDTVSGEATLNGIGECFGLADANVSWKIDGKKHEFQLSDNGNHHKQAIDRIVALLEEQGIKQDIVAVGHRVVHGGEKFTQTVKIDETVLQEIENLSDLAPLHNPAHVVGMRAAIAAFPALSQYAVFDTAFHQTMPAKAFTGAISSKLYDDYGIRRYGFHGTSHYFVSREAAKVINKPIEKSSFISVHLGNGASVCAIKDGQSVDTSMGFTPLSGLMMGTRCGDLDPGIIEFLLKKGWSTEQVFKELNSNSGFLGVSGLTSDCRGVIEAMEEGHAGATLAFEIFTYRVAKYIASYMVALDELDGIIFTGGIGENSLPIRRQILKSLKIFGYREDEVANADARFGKGGVITQANTPIAMVIPTNEEWVIAKESMALLHA
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q9KMT5
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MSNSYVLVINSGSSSLKFAVIDSQTGEALISGLGECFGMPEAVISWKYQGEKTEEAITAADHHHQHAINRIVGLMESLGFAQDLVAVGHRIVHGGEKFTSTVRIDEEVLAEIESLSDLAPLHNPAGAIGIQAAMAAFPSLPQFAVFDTAFHQTMPKKAFTGAISHELYKQYGIRRYGFHGTSHYYVSREAAKMLNKPIEQASFISVHLGNGASVCAISNGQSVDTSMGFTPLAGLMMGTRSGDLDPGIIEFLMKKGWSQEKVFETLNKKSGFLGVSGLTSDARGILEAMENGHEGAKLAFEVFTYRVAKYIGSYLIPLDHLDAIIFTGGIGENSLPIRREILGNLKLLGFVEDEKGNEAARFGKAGIIAKSELLNAVAMVIPTNEEFVIAQQSVELL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q87IJ5
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MSNSFVLVINSGSSSLKFAVIDSVSGDAVLSGLGECFGLSDARMSWKFNGEKKEISIEGDDSHHKIAIGKLVGLTEELGLAQDIVAVGHRIVHGGEKFTKTVRITEEVTQEIEKLADLAPLHNPAGAIGIRAAVEAFPSLPQFAVFDTAFHQTMPQRAFTGAIAKELYTDFGIRRYGFHGTSHYFVSREAAKMINKPIEESSFISVHLGNGASVCAINNGESVDTSMGFTPLSGLMMGTRCGDLDPGIIEYLLKKGWSQEKVFNSLNKASGFLGVSGLTSDARGILEAMEEGHEGAALAFQVFTYRVSKYIASYLAALDSFDGIIFTGGIGENSMPIRREILKNLKLLGFVEDVKGNEDARFGNAGVIATSELLGAKALVIPTNEEWVIAQQSVELL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q8D7K4
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MSNSFVLVINSGSSSLKFAVINSVTGEAVLSGLGECFGLEDARMGWKYSGEKTEIAIEGEDNHHKIAIGKLVGLTEELGLTKDIVAVGHRIVHGGEKFTSTVRINEEVTAEIEKLADLAPLHNPAGAIGIRAAMEAFPALPQFAVFDTAFHQTMPKRAFTGAIANELYTDFGIRRYGFHGTSHYFVSREAAKMLNKPIEESSFISVHLGNGASVCAINNGESVDTSMGFTPLSGLMMGTRCGDLDPGIIEYLLKKGWSQEKVFNSLNKASGFLGVSGLTSDARGILEAMEQGHEGATLAFQVFTYRVAKYIASYLAALDSFDGIIFTGGIGENSLPIRREILKNLKLLGFVEDEKGNEDARFGNAGVIATSALLNAVAMVIPTNEEFVIAQQSVELL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q7MEL2
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MSNSFVLVINSGSSSLKFAVINSVTGEAVLSGLGECFGLEDARMGWKYSGEKTEIAIEGEDNHHKIAIGKLVGLTEELGLTKDIVAVGHRIVHGGEKFTSTVRINEEVTAEIEKLADLAPLHNPAGAIGIRAAMEAFPALPQFAVFDTAFHQTMPKRAFTGAIANELYTDFGIRRYGFHGTSHYFVSREAAKMLNKPIEESSFISVHLGNGASVCAINNGESVDTSMGFTPLSGLMMGTRCGDLDPGIIEYLLKKGWSQEKVFNSLNKASGFLGVSGLTSDARGILEAMEQGHEGATLAFQVFTYRVAKYIASYLAALDSFDGIIFTGGIGENSLPIRREILKNLKLLGFVEDEKGNEDARFGNAGVIATSALLNAVAMVIPTNEEFVIAQQSVELL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B0CB11
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MKILVLNAGSSSHKCCLYAIEGPLPDHPAPPLWEAQLDWHDPNHASLKVKTKRENLEEDLSDVSRADALSHLLTTLWHGPTQVIQMAQEINVVGHRVVHGGQDYQSSVVVTSEVKTAIADLIPLAPNHNPANLEGIKLIEQLLGNVRQVAVFDTAFHSHLPEVAAIYPGPYDWQQQGIRRYGFHGISHQYCTQRTAEILGRGVDRLIICHLGNGASLTAVKQGQSIDTSMGFTPLEGLMMGTRSGSIDPGILIHLMRQGYDADQLDHMLNKASGLKGISGVSHDLREIEQAIAQDNAQAKLARDLYLHRLKACLGSMLMSLGGVDVLVFTGGIGEHSASVRAETCEALAFLGLKLDPILNRKSPVDQDIAAVDSKVRVLVIKTQEDWAIAQSCYEQCC
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A3DE81
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MNILVINTGSSSLKYQLIDMTNESVLAKGVCDRIGLEHSFLKHTKTGGETVVIEKDLYNHKLAIQEVISALTDEKIGVIKSMSEISAVGHRIVHGGEKFKESAIIDEDVMKAIRDCVELAPLHNPSNIIGIEACKQILPDVPMVAVFDTAFHQTMPRHAYIYALPYEIYEKYKLRKYGFHGTSHKYVAHRAAQMLGKPIESLKLITCHLGNGASICAVKGGKSVDTSMGFTPLQGLCMGTRSGNVDPAVITYLMEKEKMNINDINNFLNKKSGVLGISGVSSDFRDVQDAAEKGDDRAQLALDIFCYGVRKYIGKYIAVLNGVDAVVFTAGIGENNAYIRREVLKDMDFFGIKIDLDKNEVKGKEADISAPDAKVKTLVIPTNEELEIARETLRLVKNL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A9NFI4
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MKILSVNAGSSSLKFQLLQMPEEFEIASGLVERIGNKNAEFKIKFNGSSKTQSDLVVLDHSVAVDLVIKGLLENKVIASLDEIQGVGHRVVQGGQLFKESVVIDDDVVIKIASLNDLAPLHNPANIIGINAFRKAISNVIHVAVFDTTFHQTMPEENFLYGTPYEWYTKHGVRKYGFHGTSHQYVSELAHARLGKDHSRIIVAHIGNGASITAVRDGKSIDTSMGLTPLEGFPTGTRSGNVDPAIFQLMQQKEGYSLEKTLNELNKNSGYLGISGVSHDSRDIIAAAEGGNKRAQLALDIQAKRIVDYIASYYVLLGGLDALVFTAGIGENAKEVRKLICDRLGVLGIKLDDNKNNSRGDKEISSDASNVKIWVIPTNEEVMIARDVLRLQNK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A3N011
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MSKNLILILNCGSSSLKFAVLDPKTGDEKLSGLAEAFNLEDARIKWKLHGEKGNADLGAGAAHSEALTFIANELLSEELRSSIGAIGHRIVHGGEQFTSSVVINDDVVKGIEHAIQFAPLHNPAHLIGIKEAFRIFPELKEKNVAVFDTAFHQTMPEEAFLYALPYKLYKEHGIRRYGAHGTSHLFITSQVAELAGKPVDQTNAIICHLGNGGSVSVVRNGKCIDTSMGLTPLEGLVMGTRSGDIDPAIVFYLYKNLGMSMEQIEDTLVKKSGLLGLTEVTSDCRYAEDNYEDASKPEAKRALDVYSYRLAKYIGAYMAILGDDHLDAIAFTGGIGENSGHVRELALNHLKLFGVKLDVERNLAARFGKSGVITADDSTFKAVVIPTNEELVIAQDTAKLAL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B3H169
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MSKNLILILNCGSSSLKFAVLDPKTGDEKLSGLAEAFNLEDARIKWKLHGEKGNADLGAGAAHSEALTFIANELLSEELKSSIGAIGHRIVHGGEQFTSSVVINDDVVKGIEHAIQFAPLHNPAHLIGIKEAFRIFPELKEKNVAVFDTAFHQTMPEEAFLYALPYKLYKEHGIRRYGAHGTSHLFITSQVAELAGKPVDQTNAIICHLGNGGSVSVVRNGKCIDTSMGLTPLEGLVMGTRSGDIDPAIVFYLYKNLGMSMEQIEDTLVKKSGLLGLTEVTSDCRYAEDNYEDASKPEAKRALDVYSYRLAKYIGAYMAILGDDHLDAIAFTGGIGENSGHVRELALNHLKLFGVKLDVERNLAARFGKSGVITADDSTFKAVVIPTNEELVIAQDTAKLAL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B0BNS1
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MSKNLILILNCGSSSLKFAVLDPKTGDEKLSGLAEAFNLEDARIKWKLHGEKGNADLGAGAAHSEALTFIANELLSEELKSSIGAIGHRIVHGGEQFTSSVVINDDVVKGIEHAIQFAPLHNPAHLIGIKEAFRIFPELKEKNVAVFDTAFHQTMPEEAFLYALPYKLYKEHGIRRYGAHGTSHLFITSQVAELAGKPVDQTNAIICHLGNGGSVSVVRNGKCIDTSMGLTPLEGLVMGTRSGDIDPAIVFYLYKNLGMSMEQIEDTLVKKSGLLGLTEVTSDCRYAEDNYEDASKPEAKRALDVYSYRLAKYIGAYMAILGDDHLDAIAFTGGIGENSGHVRELALNHLKLFGVKLDVERNLAARFGKSGVITADDSTFKAVVIPTNEELVIAQDTAKLAL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C4Z917
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MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHKEAIQMVLDALVNPKTGAVKSLAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAPLHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYLYGLPYEYYEKYKVRRYGFHGTSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTRSGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAAVEVFSYRVAKYIGAYAAAMNGVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDKTRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B1YKC5
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MAKIMAVNAGSSSLKFQLLEMPNETMIAVGLVERVGKDDAIFTIKYGEGQKFTDVLPLATHKEAVELSLEKLMEFGIISSYDEIKGVGHRVLHGKEKYADSVIITEDVMQDIESYTELGPLHIPPNLIGIRAFQAILPNVPQVAVFDTAFHQTMPEENFLYSLPYEYYTEYGIRKYGFHGTSHKYVTERASELLGRPLQDLRLISCHLGSGASIAAVAGGESIDTTMGFTPLEGITMGTRSGSLDPALIPFLMEKTGKTAEDVLNVMNKESGIYGLSGLSSDLRDVQTAAKEGNHRSEMALRIFANRIHGYIGQYAAEMNGVDAIIFTAGVGENSDSIRERVLRGLEFMGVYWDPSLNNGARGEELFINYPHSPVKVIIIPTNEELMIARDTVRVGGLVEQNA
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C4L493
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MTKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHTHKEAVELTLEKLIELDIIQSFDEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGPLHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFLYSLPYEYYTEHGVRKYGFHGTSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTRSGSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVSLKIFSNRIHGYIGQYAAEMNGVDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNGARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVEAHA
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A7HL30
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MRVLVVNCGSSSIKYQFLDMDTEQVLCKGLAERIGIPGSRIVHKKDDQKVVVEKPMKDHEDALKYVLELVVDEKVGGVKDLKEIDAVGHRVVHGGEKFSGSVLIDEEVMRALEEYSYLAPLHNPPNIMGIRAMMKLLPGVPNVAVFDTAFHSKMPAKAYLYAIPYEYYKKYKIRRYGFHGTSHRYVSKRTAEILGLDYHKSKIITVHLGNGASIAAVMNGHSIDTSMGFTPLEGLVMGTRSGDIDPSIVTFLMEKEGLTAEEVYTILNKKSGVLGLTDGFSSDMRDIEGKALEGDPVCRLALDIYEYRIAKYIGAYIAAMNGVDAIAFTAGVGENSPITRKEICENYLSYLGIKIDDEKNNVKGEERIITTPDSKVKVLLVPTNEELMIARDTKEIIEKGLKQLEY
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B0S1N0
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MKVLVINCGSSSLKYQLFDMTDESVLCKGLVERIGIEGSKLTHKVNGEKLVVEEPMKDHTEAINHVFDALLDEKYGVIKSLDEVSAIGHRVLHGGDKLTESCIIDDKVKDKIREFIKFGPLHNPANLMGIEACEKLAPGKKNIAVFDTAFHQTMPAKTFMYAIPYEYYEDYRLRKFGFHGTSHRYITLRTQQLLGKEDINIITVHLGNGSSIAAVKNGKCYDTSMGLTPLEGLLMGTRSGDLDPTVMTFLMNEKGYSADEMNQILNKKSGVLGVSGISSDFRDLEEEAEKGNDRAQLALDMFIERVKRYIGGYMAELGHVDAICFAGGIGENSSSMRKDILDTFEELGVKLDLEKNNTREEALISADDSKVKVYVVPTNEELMIARDTLELAK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A5FE24
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MKILIINSGSSSIKYQLMVMPANEVICSGMIDRIGLETSNITFKTVSNSFEEILPVPTHKVGLQKVADMLLDAETGVIKTTSEITAVGHRVVHGGSYFSNTTVITEEVKEKIKELSELAPLHNPAHLVGINVAEEIFASAKQVAVFDTAFHQTIPVEAHKYAIPNFLLTEHKVRVYGFHGTSHKYVSEKAINYLEKGSKIITIHLGNGCSMTAVKDGKSIDTTMGFSPANGLVMGTRAGDIDQSVIFYMVKSLGYTPDEVNSILLKQSGMLGLTGYSDLRDIESKASEGNKDCQLALLMNAYRIRKTIGSYAAALNGLDAIVFTAGIGENSSFMRNLICTDMDYFGIEIDKEKNQIRSKELREINTPNSIVKILVVPTDEEFEIANQVYQLLEN
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q0BPA5
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MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIVAIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPYELTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPSIFAYIISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFTGGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q9F1X7
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MSKIIAVNAGSSTLKFKLYEMPEENVLAEGVIERIALPASHVEIKYGDGKKYEKTTDVKNHEQAIQILLDQLLDLDIIKEYSEINGVGHRVVAGGEYFDKSVVITPDVLKKIESLTELAPLHEPANVLGIKAFKKVLPDIISVAVFDTAFHATLPEKNFLYSLPYEYYEKYSARKYGFHGIGNRYVSQRAAELLGKPAEDLKMIITHLGAGASICPVKNGKSFDTSMGFTPVTGITMATRSGDVDPSLLAYVMEKEGMTDINEMIKVLNTKSGLLGISGVSADMREVEAAQATNPRAKVAREIYVNRIIRYVGAYLAEMGGADAIVFTAGVGENSITIRKEVAEGLNYFGIGVDNEKNDVRGVVRDISAKDSKIKTLLVPTDEELMIVRDVQTLANK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q8RED7
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MKILVINCGSSSLKYQLINPETEEVFAKGLCERIGIDGSKLEYEVVAKDFEKKLETPMPSHKEALELVISHLTDKEIGVIASVDEVDAIGHRVVHGGEEFAQSVLINDAVLKAIEANNDLAPLHNPANLMGIRTCMELMPGKKNVAVFDTAFHQTMKPEAFMYPLPYEDYKELKVRKYGFHGTSHLYVSGIMREIMGNPEHSKIIVCHLGNGASITAVKDGKSVDTSMGLTPLQGLMMGTRCGDIDPAAVLFVKNKRGLTDAQMDDRMNKKSGILGLFGKSSDCRDLENAVVEGDERAILAESVSMHRLRSYIGAYAAIMGGVDAICFTGGIGENSSMTREKALEGLEFLGVELDKEINSVRKKGNVKLSKDSSKVLIYKIPTNEELVIARDTFRLAK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C1A9T6
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MNILVLNAGSATLKFQVVVTDAQRIAADQDEKLIRGQIERIGGESVITLRLPDGSSRKRTAALRDLRAAVDWLVGFVTSAESGTGLSARADLHAVGHRVVHGGEQFRNSVRVDDGVLRGIEETIELAPLHNPHNLRGIEAARAALGDGVPQVAVFDTAFHQTLPEHAYLYAIPYPLYRRHKVRRYGFHGTSHRSIAYRFRKLTGRAKADVRIVTLHLGNGCSACAIKDGQSIDTSMGFTPLEGLVMGTRAGDIDAALLDYIGAKEGLSPPQVEAMLNSQSGLLGISGLTNDMRDLLAEANELRDRRARLAIEMFCYRARKYVGSYLAAMGGADAVVFAGGVGENAPEVRALICEGLQWAGLHIDADRNQALVGGQEGRFSTEGAALEAWVVPTDEELLIARDTYRAVGDGAV
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q5KW66
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MAKVLAINAGSSSLKFQLFEMPAETVLTKGVVERIGFDDAIFTIVVNGEKHQEVTAIPDHAAAVKMLLDKLIRYGIIRSFDEIDGIGHRVVHGGEKFSDSVLITEDVIKQIEEVSELAPLHNPANLVGIRAFQEVLPDVPAVAVFDTAFHQTMPEQSFLYSLPYEYYTKFGIRKYGFHGTSHKYVTQRAAELLGRPIEQLRLISCHLGNGASIAAVEGGKSIDTSMGFTPLAGVAMGTRSGNIDPALIPYIMEKTGMTADEVIEVLNKKSGMLGLSGISSDLRDLEKAAAEGNERAELALEVFANRIHKYIGSYAARMCGVDAIIFTAGIGENSEVVRAKVLRGLEFMGVYWDPILNKVRGKEAFISYPHSPVKVLVIPTNEELMIARDVMRLANL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q39WV0
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MVILALNCGSSSVKYQLFDWEKKEVVAKGMVERVIIGDSFIMHEVPGRETYRKEYECPDHKVAIDLIIRTLVDGEHGVLKDINEISAVGHRVVHGGEMFTRSVLIDEKVLDAVKDVQHLAPLHNPPNIAGIEAAQAVLPSVPHVAIFDTAFHQTMPEHAYLYPLPYEWYEKYGVRRYGFHGTSHLFVSKRAAVLLGKKPSDCNIITMHIGNGVSHCAIRGGVSIDTSMGLTPLEGAVMGTRCGDIDPAIPAFMMQKENLSAKEIDSILNKKSGVLGVTGRFTDRRDVIENANNGDHRCKVALEIEAYRLKKYIGTYMAVLGRLDAVVFTAGVGEMGWPIREKTIEGLEGIGIKLDRERNKSAMTRKRETLITTDDSPIKVFVIPTDEELVFTEDVVAILDGTYTDHMNFDYSFARQDFVRS
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q749N5
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MIILALNCGSSSVKYQLFDWERKEVVAKGMVERVIIGDSFIMHEVPGRETYRKEYECPDHQVAIDLIIRTVVDADHGVLKDINEISAVGHRVVHGGEMFTRSVLIDEKVLDAVKEVQHLAPLHNPPNIAGIEAAQAVLPHVPHVAIFDTAFHQTMPEHAYLYPLPYEWYEKYGVRRYGFHGTSHLYVSKRAAVLLGKTPSECNIITMHIGNGVSHCAIKGGVSVDTSMGLTPLEGAVMGTRCGDIDPAIPAFMMQKENLSAKEIDSILNKKSGVLGVTGRFTDRRDVIEHASNGDHRCKVALDIEAYRLKKYIGTYMAVLGRLDAVVFTAGVGEMGWPIREKTIEGLEGIGIKLDRERNKGAMTRKRESLITTDDSPIKVFVIPTDEELVFTEDVVAILNGTYTDHMNFDYSFARTDFVRK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C5D683
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MSKILAINAGSSSLKFQLFEMPSETVLTKGIVERIGFDDAIFTITVNGEKIQEVTAIPNHAVAVKMLLDKLISHGIIRSFDEIDGIGHRVVHGGEKFSDSVLITDEVLKQIEEVSELAPLHNPANIVGIKAFQEVLPNVPAVAVFDTAFHQTMPEQSFLYSLPYEYYTKFGIRKYGFHGTSHKYVTQRAAELLGRPIEQLRLISCHLGNGASIAAVEGGKSIDTSMGFTPLAGVAMGTRSGNIDPALIPYIMQKTGMTADEVLEVLNKKSGMLGISGISSDLRDLEKAAAEGNKRAELALEVFANRIHKYIGSYAARMCGVDAIIFTAGIGENSEVIRAKVLRGLEFMGVYWDPALNKVRGKEAFISYPHSPVKVLVIPTNEEVMIARDVVRLANIG
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B8F420
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MSKNILILNCGSSSLKFAILDPASGDEKLSGLAENFNLVDARIKWKLNGEKGAADLGAGAAHSEALNYIVKNILSAELKDSIGAIGHRIVHGGEKYTSSIVITDEVVAGIKEAAAFAPLHNPAHLIGIEEAFKAFPELKEKNVAVFDTAFHQTMPEHAYLYALPYSLYKEHGVRRYGFHGTSHYYVSREVAKVVGVEPSKVNVITCHLGNGASVAAIRNGKCIDTSMGFTPLEGLVMGTRSGDLDPAIIFFMHNTLGMSVKEIEETLVKKSGLLGLTEVTSDCRYAEDNYATHADAKRAMDGFCYRLAKYIGAYMAVLGDDHLDAIVFTGGIGENAGLVRELTLNYLKLFGIKVDSEKNTAARFGKSGEITAADSAFRAFVIPTNEELVIAQDTACLAL
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B7KGG9
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MKILVLNAGSSTQKSCLYDLTGDTLPQAPPKPIWKGDIDWTIATDHGLLEIKANGVEKKLNLSADDHLKGMSQMLDSLVQGETKVIDDLSEIEIVGHRVVHGGLNYTQATLITQEVKQTIADLIPLAPTHNPAHLEGIETVEKLLGNVPQLAVFDTAFHSTLPLEVAAYPLPYEWLEKGLRRYGFHGISHQYCVHRAAELLGKPLNSLKLINCHLGNGCSLAAVKDGISINTTMGFTPLEGLMMGSRSGSIDPEIPIFLIRDHGFTPEDVITVLNKKSGLKGVSGVSSDLRAIQKAIQEGNEKAQLAFKMYIHRLRFYIGAMLASLGGLDALIFTAGVGENSSEVREQACEAFGFLGLKLDQAKNESRPVDEDIATPDSKVRVLVIHTEEDWAIAKECWHQLTQK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q7NLW9
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MKVLVLNAGSSSQKSCLYDLPHTQLPQEPPQPLWEAQIDWPHGGDGAKLKIKTVHHRHEKTLQGGSRSEDSARMLETLYSGETRVIADPSEIEMVGHRVVHGGEAYRESTRITPEVKAAIDQLARFAPVHNPANLAGIEALEALLGPQVPQIAVFDTAFHSRLPAAAYVYPGPYEWLDQGIRRYGFHGISHRYCAERAAQILGRDLAQLRLITCHLGNGCSLAAVQGGFSIDTTMGFTPLEGLMMGSRSGSVDPGILIHLMRQADYTVDKLDHILNQASGLEGVSGISNDLRPLFKAIDEGNARAKLALDIYIHRLRAGIGAMAVSLGGLDALIFTAGVGENAAPVRAGACEALGFLGVALDPQKNNGRPRDADIAAADSAVRVLVIHTQEDWAIARECWQHLRR
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q7VLI5
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MSQNLILILNCGSSSLKFAILDPINGDEKLSGLAESFYLDDARIKWKFNGEKGNADLDAGAAHTEALNFIVSNILTDELKQSIGAIGHRIVHGGEKFTSSVVITDEVVKGIEEVIQFAPLHNPAHLIGIQEAFRIFPELKDRNVAVFDTAFHTTMPEQAYLYALPYSLYKDHGVRRYGAHGTSHYFVSREAARRLNVAEDKVNVITCHLGNGGSVSAIRHGECIDTSMGLTPLEGLVMGTRSGDIDPAIIFYMHDTLGMSVEEINNTLTKKSGLLGLTEVTSDCRYAEDNYETDDAARRAMEVYCYRLAKYIGSYMAVIGERLDAIVFTGGIGENSAHVREITLNHLKLFGYQVDDARNLAARFGNEGVITAEGSPLAMVIATNEELVIAQDTARLTITK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q4QL95
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MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILTDELKNSIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFNAFPHLKDKNVVVFDTAFHQTMSEEAFLYALPYSLYKEHGVRRYGAHGTSHYFISREVAEYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTRCGDIDPAIVFYLYKTLGMSMEQIEETLVKKSGLLGLTEVTSDCRYAEDNYDNASKPEAKRALNVYSYRLAKYIGAYMAVLGDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNERNLAARFGKDGVITTDDSAFKAIVLPTNEELVIAQDTARLCF
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A5UCQ6
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MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILTDELKNSIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFNAFPHLKDKNVVVFDTAFHQTMSEEAFLYALPYSLYKEHGVRRYGAHGTSHYFISREVAEYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTRCGDIDPAIIFYLYKTLGMSMEQIEETLVKKSGLLGLTEVTSDCRYAEDNYDNASKPEAKRALNVYSYRLAKYIGAYMAVLGDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIQIDNERNLAARFGKDGVITTDDSAFKAIVLPTNEELVIAQDTARLCF
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A5UIW8
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MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILNDELKNSIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFKAFPHLKDKNVVVFDTAFHQTMPEEAFLYALPYSLYKEHGVRRYGAHGTSHYFVSREVAEYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTRCGDIDPAIVFYLYKTLGMSMDQIEETLVKKSGLLGLTEVTSDCRYAEDNYDDESKPETKRALNVYSYRLAKYIGAYMAVLGDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDHERNLATRFGKDGVITTDDSAFKAIVLPTNEELVIAQDTAKLCF
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C1CA89
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MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGENAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q8P2X6
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MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q1JE09
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MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q1JNW6
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MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q1JJ12
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MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q1J8W0
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MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGQSADTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A2RC62
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MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEHIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKYIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B1I9A0
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MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGCSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGENAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B8ZPA4
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MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGENAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q48VQ0
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MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGEISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q97NI3
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MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGENAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q9A1T1
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MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B5XJD9
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MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYGEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLSWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C0MEF7
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MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTVKYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVVVDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYHGQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGGVSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGENAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVVSTDEELCIARDVERLKQTIS
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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A4VSL6
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MSKTIAINAGSSSLKWQLYQMPEETVLAAGIIERIGLNDSISTVKYDGKKESEVLDIPNHTVAVKILLEDLLKHNIIAAYEEITGIGHRVVAGGEYFKESAVISQQEIEQIEELSALAPLHNPAHVAAMRAFEEVLPEVLNVAVFDTAFHTTMPKHAYLYPIPQKYYTDYKVRKYGAHGTSHYYVAHEAAKVLGRPIEELKLITAHIGNGVSITANYHGESVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIANVEELKDAADVVNMLNKQSGLFGVSGFSSDMRDIEAGIQAHNPDAVLAYNIFIDRIKKFIGQYLAVLNGADAIVFTAGMGENAPLMRNDVVEGLSWFGIELDLEKNVFGNYGDISTAESKVRVLVISTDEELVIAREVERLK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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Q03IL2
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MTKTIAINAGSSSLKWQLYEMPEEVVLAKGLIERIGLRDSVSTVKFADRSESQTLDIADHVQAVKILLDDLIRFDIIKSYDEITGVGHRVVAGGEYFKESSLVDEYALAKIEELSASAPLHNPGAASGIRAFKELLPDITSVAVFDTAFHTSMPEVAYRYPVPNRYYTDYQVRKYGAHGTSHQYVSQEAAKLLGKPIEETKIITAHVGNGVSITAVDGGKSVDTSMGLTPLGGVMMGTRTGDLDPAIIPFIIDREPDMADAERIRHVFNKESGLLGISEKSSDMRDIIAGKEAGDEKCTLAYDLYVDRLRKYIAQYFGVMNGADAIVFTAGIGENSADVRASVLDGLTWFGIEVDPEKNVFGRVGDITTADSAVKVFVIPTDEELVIARDVERLKTK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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B9DT06
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MSKTIAINAGSSSLKWQLYQMPEETVLAQGIIERIGLKDSISTVKFNGNKEEQVTDIPDHTTAVKILLNDLIHLNIISAYDEITGVGHRIVAGGEYFTDSVLVDEKVIEQVEELSALAPLHNPGAAAGIRAFREILPDITSVCVFDNAFHMTMQKHTYLYPIPQKYYTEHKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYIIERDPELKDAADAINMLNKKSGLGGVSGISSDMRDIEAGLQEKNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGENAPLMRQDVINGMSWFGMEIDPEKNVFGYRGDISTPNSKVKVLVISTDEELCIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C1CGX4
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MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEWNHEASLAYEMYVDRIQKHIGQYFAVLNGADAIVFTAGVGENAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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C1CMZ0
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MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGENAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
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Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. acetate + ATP = acetyl phosphate + ADP Mg(2+). Can also accept Mn(2+). Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. Homodimer. Belongs to the acetokinase family.
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P30544
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MENDTWENESSASNHSIDETIVEIPGKYQTMEMIFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYSLYIIKGYWPLGPIVCDLWLALDYVVSNASVMNLLIISLERXFCVTKPLTYPARRTTKMAGLMIAAAWLLSFELWAPAILFWQFIVGQRTVPSGECYIQFLSNPAVTFGTAIAAFYLPVVIMTILYIHISLASRSRVRRHCPETRQEKKKPISSMKSLLIKQTKNIPKQDAGDKVVEKKNGVSNGKIEKSMTNLQTAEEKETSNESSSASLSHNPPEKQPLSEASSGVVLAPTQSMPPLPAKANTASKWSKIKIVTKQTGNECVTAIEIVPECAIPLPEQANNRPVNVARKFASIARNQVRKKRQMAAREKKVTRTIFAILLAFIITWTPYNVMVLINTFCQTCIPETIWYIGYWLCYVNSTINPACYALCNATFKKTFKHLLMCQYKSIGTAR
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily.
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Q96RG7
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MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNPNPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
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P56490
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MEGDSYHNATTVNGTPVYHQPLERHRLWEVISIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGVMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTEAEKRKPAHRALFRSCLRCPRPTLAQRERNQTSWSSSRRSASTSGKPSQATDPSTNQAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSRGKESPGEEFSSEDAEETFVKAQTEKHDSDTPNYFLSPAAAHRPKSQKCVAYKFRLVVKADGTQENNNGCHKVKIMPCSFPVAKEPSTKGLNPNPSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
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Q0VBI9
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MEGESYHNETTVNGTPVNHQALERHGLWEVITIAAVTAVVSLMTIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVAEVKKRKPAHRTLLRSFFSCPRPSLAQRVRNQASWSSSRRSTSTTGKPTQATDLSADWEKAEQVTNCSSCPSSEDEAKATTDPVFQVVCKNEAKESPGKEFNTQETKETFVSPRTENNDYDTPKYFLSPGAAHRLKSQKCVAYKFRLVVKADGTQETNNGCRKVKIMPCSFPVSKDPSTKGLDPHLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKKKKVEEKLYWQGNSKLP
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
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Q5IS53
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MEGDSYGNATTINGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSVSVTKAEKRKPAHRALFRSCFRCPRPTLVQRERNQASRSSSHRSTSITGKPSQATGPSTNWAKAEELTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEEAEETFVKGQTDKNDCDSPDYFLSPAAAHRPKSQQCVAYKFQLVVKADGTQETNNGCHKVKIMPCSFPVAKEPSTKGLSPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVALWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCQWKKKKVEEKLYWQGNSKLP
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
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P08911
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MEGESYNESTVNGTPVNHQALERHGLWEVITIAVVTAVVSLMTIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVAEAKKREPAQRTLLRSFFSCPRPSLAQRERNQASWSSSRRSTSTTGKTTQATDLSADWEKAEQVTTCSSYPSSEDEAKPTTDPVFQMVYKSEAKESPGKESNTQETKETVVNTRTENSDYDTPKYFLSPAAAHRLKSQKCVAYKFRLVVKADGTQETNNGCRKVKIMPCSFPVSKDPSTKGPDPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKKKKVEEKLYWQGNSKLP
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
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Q5IS98
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MEGDSYGNATTINGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSVSVTKAEKRKPAHRALFRSCFRCPRPTLVQRERNQASRSSSHRSTSITGKPSQATGPSTNWAKAEELTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEEAEETFVKGQTDKNDCDSPDYFLSPAAAHRPKSQQCVAYKFQLVVKADGTQETNNGCHKVKIMPCSFPVAKEPSTKGLSPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVALWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCQWKKKKVEEKLYWQGNSKLP
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
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Q3ZPN4
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MASPSSPLVFSVNRCVPQIVRPANPTPREVKQLSDIDDQEGRRFQIPVIMFYRNNPLMEGKDPVKVIREALGKALVYYYPFAGRLIEGDNRKLMVDCTGEGVLFIEADADTTLENLGDAIQPMCPCFEELLYDVPGSTTILGSPLILIQVTRLRCGGFIFALRLNHTMSDAAGLIQFLDTIGEMAQGLSVPSLLPIWQRELLNARNPPRITRIHHEYEKVTNTKGTLMAMDENSLVHRSFFFGREEIRALRNRLPASLGACSTFEVLMACVWRCRTIAFAVDPDEVVRISCIINMRGKHGFELPPGYYGNAFVTPASITKAGMLCKNPLEFAIRLVKKAKAEMSQEYIKSVADLMVIKGRPLFTQPGNFTVSDVTRAGLGEVDFGWGKPVYGGVARACPIISFRMLFRNSKGEEGSVIPIWLPPPVMERFEQELKRMTKKAELLITSML
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Acyltransferase that catalyzes the formation of methyl anthranilate, a compound implicated in the 'foxy' odor character of Concord grapes. Can use a variety of alcohol substrates when assayed with both benzoyl-CoA and anthraniloyl-CoA. anthraniloyl-CoA + methanol = CoA + O-methyl anthranilate benzoyl-CoA + benzyl alcohol = benzyl benzoate + CoA K(+), Ca(2+), Mg(2+) and Mn(2+) increase enzyme activity while Cu(2+) and Zn(2+) inactivate the enzyme. kcat is 0.045 sec(-1) with benzoyl-CoA as substrate (with native enzyme). kcat is 0.022 sec(-1) with anthraniloyl-CoA as substrate (with native enzyme). kcat is 0.0035 sec(-1) with methanol as substrate (with native enzyme). kcat is 0.045 sec(-1) with benzoyl-CoA as substrate (with recombinant enzyme). kcat is 0.01 sec(-1) with anthraniloyl-CoA as substrate (with recombinant enzyme). kcat is 0.0058 sec(-1) with methanol as substrate (with recombinant enzyme). Optimum pH is 7.0-9.0. Monomer. Expressed in berry outer mesocarp, but not in berry skin. Expression starts when the berries began to change the color. It increases throughout berry development to reach a maximum level in very mature berries. No AMAT activity can be detected in Vitis vinifera grapes. Belongs to the plant acyltransferase family.
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A0A3G5BIW4
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MSTTTLDAAVIGTGVAGLYELHMLREQGLEVRAYDKASGVGGTWYWNRYPGARFDSEAYIYQYLFDEDLYKGWSWSQRFPGQEEIERWLNYVADSLDLRRDISLETEITSAVFDEDRNRWTLTTADGDTIDAQFLITCCGMLSAPMKDLFPGQSDFGGQLVHTARWPKEGIDFAGKRVGVIGNGATGIQVIQSIAADVDELKVFIRTPQYALPMKNPSYGPDEVAWYKSRFGELKDTLPHTFTGFEYDFTDAWEDLTPEQRRARLEDDYENGSLKLWLASFAEIFSDEQVSEEVSEFVREKMRARLVDPELCDLLIPSDYGFGTHRVPLETNYLEVYHRDNVTAVLVRDNPITRIRENGIELADGTVHELDVIIMATGFDAGTGALTRIDIRGRDGRTLADDWSRDIRTTMGLMVHGYPNMLTTAVPLAPSAALCNMTTCLQQQTEWISEAIRHLRATGKTVIEPTAEGEEAWVAHHDELADANLISKTNSWYVGSNVPGKPRRVLSYVGGVGAYRDATLEAAAAGYKGFALS
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Plays an important role in the metabolism of acetone derived from propane oxidation (PubMed:17071761). Catalyzes the oxidation of acetone to methyl acetate (PubMed:17071761, PubMed:30392152). Exhibits high catalytic efficiency towards various linear and cyclic ketones, such as butanone, 2-pentanone, 2-heptanone, 2-octanone, 2-nonanone, 2-decanone, cyclobutanone, cyclopentanone and cyclohexanone (PubMed:17071761, PubMed:30392152). Elicits the highest catalytic efficiency towards butanone and cyclobutanone (PubMed:30392152). Is highly specific for NADPH and cannot use NADH (PubMed:17071761, PubMed:30392152). acetone + H(+) + NADPH + O2 = H2O + methyl acetate + NADP(+) Binds 1 FAD per subunit. kcat is 2.0 sec(-1) with NADPH as substrate. kcat is 1.4 sec(-1) with acetone as substrate. kcat is 2.1 sec(-1) with butanone as substrate. kcat is 1.9 sec(-1) with 2-pentanone as substrate. kcat is 3.9 sec(-1) with 2-heptanone as substrate. kcat is 2.2 sec(-1) with 3-methylbutanone as substrate. kcat is 1.5 sec(-1) with 2,4-dimethyl-3-pentanone as substrate. kcat is 2.0 sec(-1) with cyclobutanone as substrate. kcat is 4.3 sec(-1) with cyclopentanone as substrate. kcat is 3.6 sec(-1) with cyclohexanone as substrate. kcat is 1.5 sec(-1) with bicyclo[3.2.0]hept-2-en-6-one as substrate. kcat is 1.0 sec(-1) with phenylacetone as substrate. Optimum pH is 8.0-8.5 (PubMed:17071761). Optimum pH is 7.0-8.0 (PubMed:30392152). Optimum temperature is 35 degrees Celsius. Homotetramer. Induced by propane, 2-propanol and acetone. Belongs to the FAD-binding monooxygenase family.
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Q9CIT4
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MPVSRIKVKNRHLKKKAKKPLAFYKPATKFAGAVLIAGTLTTTHELLLQQTSPMVQAATNSTEAFIESIAASAKPVADSNGLYPSVMIAQAILESNWGSSQLSRAPYYNLFGIQGTYQGKSVVFKTQEYLNGKWVTKDMPFRVYPSFNQSFQDNAYVLKTTNFGNGPYYAKAWRANAATYQAATAALTGKYATDPNYGASLNRIISQYNLTRFDGASSAGTSNSGGSTATNTNNNSNTSSTTYTVKSGDTLWGISQKYGISVAQIQSANNLKSTVIYIGQKLVLTTSSSSSNTNSSTSSGNSAGTTTPTTSVTPAKPASQTTIKVKSGDTLWGLSVKYKTTIAQLKSWNHLNSDTIFIGQNLIVSQSAGSSSSSTGSSSASTSSTSNSSAASNTSIHKVVKGDTLWGLSQKSGSPIASIKAWNHLSSDTILIGQYLRIK
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Required for cell separation during growth. Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. The LysM domains are thought to be involved in peptidoglycan binding. Belongs to the glycosyl hydrolase 73 family.
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Q48603
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MPVSRVKVKNRHLKKKTKKPLAFYKPATKFAGAVLIAGTLTTTHELLLQQTSPMVQAATNSSEVFIESIAASAKPVADANGLYPSVMIAQAILESNWGSSQLSRAPYYNLFGIQGTYQGKSVVFKTQEYLNGKWVTKDMPFRVYPSFNQSFQDNAYVLKTTNFGNGPYYAKAWRANAATYQDATAALTGRYATDPSYGASLNRIISQYNLTRFDGASSAGNTNSGGSTTTITNNNSGTNSSSTTYTVKSGDTLWGISQRYGISVAQIQSANNLKSTIIYIGQKLVLTGSASSTNSGGSNNSASTTPTTSVTPAKPTSQTTVKVKSGDTLWALSVKYKTSIAQLKSWNHLSSDTIYIGQNLIVSQSAAASNPSTGSGSTATNNSNSTSSNSNASIHKVVKGDTLWGLSQKSGSPIASIKAWNHLSSDTILIGQYLRIK
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Hydrolyzes the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth. Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. The LysM domains are thought to be involved in peptidoglycan binding. Belongs to the glycosyl hydrolase 73 family.
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A1IHE7
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MTSTFSSLDVSAFTSAADRILAEAVTGDARVPGVVAMVTDRDRTVYSGAAGQRSLGGSAPMTTDDVFAIFSTTKAITATAALQLVEEGLLDLDAPASTYAPAIGTLQVIEGFDDAGEPILRAPKSVPTTRQLLTHTGGFGYDFFDEIYNRLAEEKGQPSVTTASRAALMTPLLFDPGERWQYGTNIDWVGQVVEGLRGKRLGEVFAERIFAPLGIENMSFILREDFRSHLTEIHARNADGSLTPMGLELPSPPEVDFGGHGLYGTVGEYMKFIRMWLNDGVGEGGRVLKAETVEMALRNHLGDLPVTMLPGVIPSLSNDAEFFPGQSKSWSLPFMINNETAPTGRPAGAQGWAGLANLFYWIDRQNGYGGYWATQILPFGDPTSFTKYMEFETAFYDALKS
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Plays an important role in the metabolism of acetone derived from propane oxidation (PubMed:17071761). Catalyzes the hydrolysis of methyl acetate to acetate and methanol (PubMed:17071761). H2O + methyl acetate = acetate + H(+) + methanol Induced by propane, 2-propanol and acetone. Belongs to the class-A beta-lactamase family.
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D6R237
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MISKDDIRAILAEGTDLGPPEQFPDDADVVMDSFTLIVLQHGLEERHGVVIDPHFEDMEQFTSIDGIHAYLTALPAER
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Involved in the biosynthesis of actinomycin (PubMed:10212227). Acts as a carrier in the transfer and thioesterification of 4-methyl-3-hydroxyanthranilic acid (4-MHA) (PubMed:10212227). Antibiotic biosynthesis. 4'-phosphopantetheine is transferred from CoA to a specific serine of the apo-form of this carrier protein. Belongs to the acyl carrier protein (ACP) family.
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Q0II68
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MKIDIHTHILPREWPDLKKRFGYGGWVQLQHNGKGEAKMLKDGKVFRVVQENCWDPEARLREMDQTGVTVQALSTVPVMFSYWAKPQDTLDLCQLLNNDLAATIASHPRRFVGLGTLPMQAPELAVKEMERCVRKLGFPGVQIGSHINEWDLNARELFPVYAEAERLNCSLFVHPWDMQMDGRMAKYWFPWLIGMPAETTAAICSMIMGGVFEKFPKLKVCFAHGGGSFPFTVGRISHGFSMRPDLCAQDNPTNPKKYLGSFYTDSLVHDPLALKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMGEFDAETKDKLKAGNALEFLGLERKQFE
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Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway (By similarity). 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2 Secondary metabolite metabolism; quinolate metabolism. Monomer. Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
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Q8T8B9
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MPICEFSATSKSRKIDVHAHVLPKNIPDFQEKFGYPGFVRLDHKEDGTTHMVKDGKLFRVVEPNCFDTETRIADMNRANVNVQCLSTVPVMFSYWAKPADTEIVARFVNDDLLAECQKFPDRLVPLGTLPMNDVQRAVEIFGKRIFFFEIWSPAKKSPEEVKRCVSMGIKGFEVGSHVAEKSLDHRDFWPLYKLTESFKLSTIMPGFCEFFENWGLTTKTPGICEELSVVLFVHPWDMHMWDGRLDKYWMPWLVGMPSETAQAICSVLMGNILVLFPKLKLCFAHGGGAYPQIRGRVSHGWNVRPDLCAGKCKVAPNKLDGLLWTDSLVHDPKALELLINTVGKEHIVLGTDYPFPLGELEVGRVVEEYKPFSAKDREDLLWKNAVKMLDIDENLLFNKDF
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Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2 Secondary metabolite metabolism; quinolate metabolism. Monomer. Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
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Q54LN9
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MENKETTTTTTTTNNGSDKKKRSLKIDLHTHILPKNWPNLKEKYGYGGWVSLDHHCSCKAKMMIDGKFFREIDSNCWDPDVRIQELNRDDVDIQVLSTVPVMFGYWAKPQDALDLAQYLNDHIAQVVSENPKRFIGLGSLPMQCTESSIQELRRCILELGLPGIQIGSNVNGKNLDDPSLFPIFEECEKLGAAVFIHPWEMVGKDRMPQYWLPWLVGMPAETCLAICSMIFGGVFQRLPNLKVCFAHGGGSFPFTIGRIEHGFNARPDLCAVVNPINPREYIGKFWVDSLVHDEEALKFLVNLMGEKKVTLGTDYPFPLGELVPGQLIESIKEFSETTKENLLGGNALEFLGLDPNKYL
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Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2 Secondary metabolite metabolism; quinolate metabolism. Monomer. Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
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Q96KY2
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MKIDIHSHILPKEWPDLKKRFGYGGWVQLQHHSKGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGLERKQFE
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Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway. 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2 Secondary metabolite metabolism; quinolate metabolism. Monomer. Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
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Q3UNW3
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MKIDIHTHILPKEWPDLEKRFGYGGWVQLQQQGKGEAKMIKDGKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGLERKLFE
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Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway. 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2 Secondary metabolite metabolism; quinolate metabolism. Monomer. Highest expression in kidney with lower levels in liver and brain. By streptozocin-induced diabetes. Repressed by low protein diet. Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
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P83662
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MKIDIHSHILPKEWPDLKKRFGYXGWVELQHHSEGEAKMLKDGKVFRVVQERFVGLGTLPMQAPXSLFVHPWDMQYWFPWLIGMPAETTTAXESMMMGGVFEKVXFAHGGGSFPFTVGRIVILGTDYPFPLGELEPGK
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Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway. 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2 Secondary metabolite metabolism; quinolate metabolism. Monomer. Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
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Q8BYC3
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MNPDLRKERAAATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREFGIADPEEIMWFKKLHMVNFVEPVGLNYSMFIPTLLNQGTTAQQEKWMHPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITRGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGSAAQSLSKACTIAIRYSAVRRQSEIKRSEPEPQILDFQTQQYKLFPLLATAYAFHFLGRYIKETYMRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVQSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTLVDINSLDSLTEAYKLRAARLVEIAAKNLQAQVSHRKSKEVAWNLTSVDLVRASEAHCHYVTVKVFADKLPKIQDRAVQAVLRNLCLLYSLYGISQKGGDFLEGNIITGAQMSQVNSRILELLTVTRPNAVALVDAFDFKDVTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYYKHLKPLQSKL
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Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain length of 10 carbons (decanoyl-CoA) in vitro. Is active against a much broader range of substrates and shows activity towards long-chain acyl-CoAs. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2 O2 + octanoyl-CoA = (2E)-octenoyl-CoA + H2O2 decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2 O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2 hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2 O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Homodimer (By similarity). Interacts with LONP2 (By similarity). Highest levels of isoform 1 are found in liver and kidney while highest levels of isoform 2 are found in white adipose tissue. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 is expressed at higher levels in brain, heart, lung, muscle, white adipose tissue and testis. Severe microvesicular hepatic steatosis, sustained activation of Ppara, spontaneous massive peroxisome proliferation and eventual development of hepatocellular carcinomas (PubMed:20195242). Null mice have strikingly increased levels of both n-3 and n-6 very long chain polyunsaturated fatty acids (over twenty-four (24) carbons long) (PubMed:11855929). Belongs to the acyl-CoA oxidase family. Truncated N-terminus.
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Q8HYL7
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MNPDLRRERDAASFDAEKLTYILDGGSERTRRRREIENLILNDPDFKHEDLNFLTRSERYEIAVRKSATMVKKMRDFGIADPEEIMWFKKPQLINFVEPVGLTYSMFIPTLLDQGTTAQQQKWLPPTQGLQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLYTKGECYGLHAFIVPIREMGTHKPFPGIIVGDIGPKFGYDEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARSLSKACTIAIRYSLIRHQSEIRPGDPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINVDINQGNLNELPELHALTAGLKAFTSWTTNSGIEACRMACGGHGYSHCSGLPNIYVTFTPTCTFEGENTVMMLQTARFLMKSYDQVHSGKLVGGMVSYLNDLPSQRIQPQQVAAWPAMVDINNPDSLTEAYKHRAARLVEAAARNLQAEMKHRKSKEIAWNFTSVDLVRASEAHCHYVVVKLFSGNLSKIDDKPIQAVLTNLCLLYALYGISQNSGDFLQGGILTESQLTQVNQRVKELLTLIRPESAALVDAFDFQDVSLGSVLGRYDGNIYENMFEWAKKSPLNKSEVHESYHKHLKPLQSKL
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Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids (PubMed:12758125). Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)) (PubMed:12758125). Isoform 2 shows higher activity with hexadecanoyl-CoA as substrate than isoform 1 (PubMed:12758125). a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2 O2 + octanoyl-CoA = (2E)-octenoyl-CoA + H2O2 decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2 O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2 hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2 O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Homodimer (By similarity). Interacts with LONP2 (By similarity). Belongs to the acyl-CoA oxidase family.
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Q5R8F0
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MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHEDLNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKKLHLVNFVEPVGLNYSMFIPTLLNQGTTAQKEKWLLSSKGLQIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKGYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDIHSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRNLCLLYSLYGISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAEVHESYKHLKSLQSKL
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Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain length of 10 carbons (decanoyl-CoA) in vitro. Is active against a much broader range of substrates and shows activity towards long-chain acyl-CoAs. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2 O2 + octanoyl-CoA = (2E)-octenoyl-CoA + H2O2 decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2 O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2 hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2 O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Homodimer (By similarity). Interacts with LONP2 (By similarity). Belongs to the acyl-CoA oxidase family.
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P11354
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MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSKL
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Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain length of 10 carbons (decanoyl-CoA) in vitro. Is active against a much broader range of substrates and shows activity towards long-chain acyl-CoAs. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2 dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2 O2 + octanoyl-CoA = (2E)-octenoyl-CoA + H2O2 decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2 O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2 O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2 hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2 O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2 O2 + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O2 (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Homodimer. The enzyme contains three components A, B and C, the latter two being produced from the first by a proteolytic cleavage. Interacts with LONP2 (By similarity). Expressed in Schwann cells (PubMed:32169171). Expressed (at protein level) in liver (PubMed:1400324). Belongs to the acyl-CoA oxidase family.
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Q6C3Q9
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MTTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSLWRAQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQNGQGTPREQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCARIHTRQHLISSFYARIATAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPRPPYYESTLKPFLFREEEDDEICDLDE
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a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Heteropentamer composed of five different subunits. Belongs to the acyl-CoA oxidase family.
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Q9FJQ4
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MESRREKNPMTEEESDGLIAARRIQRLSLHLSPSLTPSPSLPLVQTETCSARSKKLDVNGEALSLYMRGKHIDIQEKIFDFFNSRPDLQTPIEISKDDHRELCMNQLIGLVREAGVRPFRYVADDPEKYFAIMEAVGSVDMSLGIKMGVQYSLWGGSVINLGTKKHRDKYFDGIDNLDYTGCFAMTELHHGSNVQGLQTTATFDPLKDEFVIDTPNDGAIKWWIGNAAVHGKFATVFARLILPTHDSKGVSDMGVHAFIVPIRDMKTHQTLPGVEIQDCGHKVGLNGVDNGALRFRSVRIPRDNLLNRFGDVSRDGTYTSSLPTINKRFGATLGELVGGRVGLAYASVGVLKISATIAIRYSLLRQQFGPPKQPEVSILDYQSQQHKLMPMLASTYAYHFATVYLVEKYSEMKKTHDEQLVADVHALSAGLKSYVTSYTAKALSVCREACGGHGYAAVNRFGSLRNDHDIFQTFEGDNTVLLQQVAADLLKRYKEKFQGGTLTVTWSYLRESMNTYLSQPNPVTARWEGEDHLRDPKFQLDAFRYRTSRLLQNVAARLQKHSKTLGGFGAWNRCLNHLLTLAESHIETVILAKFIEAVKNCPDPSAKAALKLACDLYALDRIWKDIGTYRNVDYVAPNKAKAIHKLTEYLSFQVRNVAKELVDAFELPDHVTRAPIAMQSDAYSQYTQVVGF
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Catalyzes the desaturation of long-chain acyl-CoAs to 2-trans-enoyl-CoAs. Active on substrates longer than C14 and mostly with C18-CoA. Activity on long-chain mono-unsaturated substrates is double than with the corresponding saturated substrates. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Binds 1 FAD per subunit. Homodimer. A number of isoforms are produced. According to EST sequences. Expressed mainly in flowers and young seedlings. Lower expression in roots, leaves and bracts. Induced by seed imbibition with a peak at day 2 and then declines steadily until day 8. Induced by dehydration and abscisic acid (ABA). Belongs to the acyl-CoA oxidase family.
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Q00468
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MALISNLKDEYDHPTKTDPDTNPKIVADIISSKEPPQPSQDVAEERSRTDWDLKEMHEFLEGDEAKSEEILRLYQSIERDPILQTRPEQFDYTKNEERESVALRINQMSKYLETEPYEKFRRRLQLMTVNDPSLGIRMLVNIGLFLNCIRGNGTQKQYDFWAKTKEAGKVKQLLRLFRYDELGHGFNVAGCEIFATFDEKTDQFIIDTPHIGATKWWIGGAAHSATHTVCYARLIVKDIDYGVKTFVVPLRDSTHNLLPGVAIGDIGPKLGRQGVDNGWIQFTEVRIPRFFMLQRWCKVDRQGNVTLPPLEQLSYISLLEGRVGMATDSYRIGARYTTIALRYAVARRQFSKGDGQPETKLIDYTLHQRRLLPYLALTYLAALGTDKLERQHDQLLKNLDKALATNNKLLLKNTIQSTKSMFVDSGSLKSTLTWLASDLINEARQSCGGHGYSAYNGFGKTYGDWAVQCTWEGDNNVLGMSAGKTIIKTVQQVLNGKQLKDSTLEFLNDAPALSSAKKAVIRIKSHVDDTDRVLKAIAGLISKYAKDLIPVSYQSWDSIGPQRVVLSKFRCHYYLLETFNERLNDRIKAKSPARPHLENIIKLYYVTNVLGPFIDEFLRFGVISPSVAKYITTEYPQKLCAAIRPYVIGLTDSFQQPDNFINSLIGRYDGNVYTNYLTNVTNVNDPTNYKAPYSEALEAMLNRASLEERERFEKSKAVAAKLSQ
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a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Belongs to the acyl-CoA oxidase family.
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P11356
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MAMLSQPNDGHDHPEKKDPDTTPKQVAGVISSQDPPHPAKDVAEERARTDWDLKEMHEFLEGDEAKSEQILRLYQSIERDPILQTRPEQFDYTQKQERELVANRINQMTKFLETEPYGKFRRRLQLMTVIDPSLGIRMLVNIGLFLNCVRGNGTQKQFDFWSNKKEAGIVKQLYGCFGMTELGHGSNVAGCETTATFDEKTDEFIIDTPHIGATKWWIGGAAHSATHTVCYARLIVKDVDYGVKTFIVPLRDSRHSLLPGIAIGDIGAKMGRQGVDNGWIQFTEVRVPRFFMLQRWCKVDRQGNVTLPPLEQLSYISLLEGRVGMATDSYRIGARYTTIALRYAVGRRQFSKKAGEPETKLIDYTLHQRRLLPYLALTYAAAVGTDRLERQHEELLANLDIALAKKDKLLLKNTITGTKSMFVDSGSLKSTLTWLAADLINETRQACGGHGYSSYNGFGKTYDDWVVQCTWEGDNNVLAMSAGKTIIKTVQQVLNGKELKDSTLEFLNAAPELSKAKKAVIRIRDHVDDVDRVLKAIAGLISKFSKDLIPISYQSWDSIGAQRVILSKLRCHYYLLETFNERLNDKIKAKSPARPHLENIIKLYYVTNILGPFIDEFLRFGVISPQVAKYITYEYPQKLCANIRPYVIGLTDSFQQPDNFINSLIGKYDGNIYTNYLESVKDVNDPSNYKAPYSEALEAMLNRSALENRERSERGKAAADILSK
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a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Belongs to the acyl-CoA oxidase family.
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O64894
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MASPGEPNRTAEDESQAAARRIERLSLHLTPIPLDDSQGVEMETCAAGKAKAKIEVDMGSLSLYMRGKHREIQERVFEYFNSRPELQTPVGISMADHRELCMKQLVGLVREAGIRPFRFVNEDPAKYFAIMEAVGSVDVSLAIKMGVQFSLWGGSVINLGTKKHRDRFFDGIDNVDYPGCFAMTELHHGSNVQGLQTTATFDPITDEFIINTPNDGAIKWWIGNAAVHGKFATVFAKLVLPTHDSRKTADMGVHAFIVPIRDLKSHKTLPGIEIHDCGHKVGLNGVDNGALRFRSVRIPRDNLLNRFGEVSRDGKYKSSLPSINKRFAATLGELVGGRVGLAYSSASVLKIASTIAIRYSLLRQQFGPPKQPEVSILDYQSQQHKLMPMLASTYAFHFSTMQLVEKYAQMKKTHDEELVGDVHALSAGLKAYVTSYTAKSLSTCREACGGHGYAVVNRFGTLRNDHDIFQTFEGDNTVLLQQVAAYLLKQYQEKFQGGTLAVTWNYLRESMNTYLSQPNPVTARWESADHLRDPKFQLDAFQYRTSRLLQSVAVRLRKHTKNLGSFGAWNRCLNHLLTLAESHIESVILAQFIESVQRCPNANTQATLKLVCDLYALDRIWNDIGTYRNVDYVAPNKAKAIHKLTEYLCFQVRNIAQELVDAFDLPDHVTRAPIAMKSNAYSQYTQYIGF
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Catalyzes the desaturation of long-chain acyl-CoAs to 2-trans-enoyl-CoAs. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Induced one day after germination with a peak at day 5 and then declines steadily until day 8. Belongs to the acyl-CoA oxidase family.
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B2R8U5
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MGSPVHRVSLGDTWSRQMHPDIESERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYFMTQNERYKAAMRRAFHIRLIARRLGWLEDGRELGYAYRALSGDVALNIHRVFVRALRSLGSEEQIAKWDPLCKNIQIIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQLICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENMLSRFAQVLPDGTYVKLGTAQSNYLPMVVVRVELLSGEILPILQKACVIAMRYSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVTVKGFTEALEKLENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQSWRSKL
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Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (PubMed:27884763). Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity). (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2 Homodimer. Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney. The disease is caused by variants affecting the gene represented in this entry. Belongs to the acyl-CoA oxidase family.
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Q8VCB0
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MGNPGDRVSLGETWSREVHPDIDSERHSPSFSVERLTNILDGGIPNTELRRRVESLIQRDPVFNLKHLYFMTRDELYEDAVQKRFHLEKLAWSLGWSEDGPERIYADRVLAGYNNLNLHGIAMNAIRSLGSDEQIAKWGQLGKNFQIITTYAQTELGHGTYLQGLETEATYDATTQEFVIHSPTMTSIKWWPGDLGRTVTHAVVLAHLICLGARHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGFENIDNGFLRLNHVRVPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLYKGFLPTLQKACTIAVRYAVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYALHFMTTSLLQFFHSSYSDILKRDFSLLPELHALSTGMKAMSSDFCAQGTEICRRACGGHGYSKLSGLPTLVTQAIASCTYEGENTVLYLQVARFLMKSYLQAQVSPGSIPQKPLPQSVMYLATPRPARCPAQTAADFRCPEVYTTAWAYVSARLIRDATQHTQTLMRSGVDQYDAWNQTSVIHLQAAKAHCYFLTVRNFKEAVEKLDNEPEIQRVLQNLCDLYALNGILTNSGDFLHDGFLSGAQVDMARTAFLDLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYQRLFEWAQKSPANTQENPAYKKYIRPLMQSWKPKL
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Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycoprostanic acids (By similarity). Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity). (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2 Homodimer. Acetylation of Lys-667 is observed in liver mitochondria from fasted mice but not from fed mice. Belongs to the acyl-CoA oxidase family.
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O02767
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MGIPVHRVSLGDAWSSRMHPDMESERCAQSFSVERLTNILDGGAQHTALRRKVESIIHGNPQFSSKDNYFMSQNELYEAATRKRYHLQKIAQRMGWTEEGRELEYAHRALSADLNLNLQGIFLKALRSLGSEEQIAKWEPLGKTFQIISTYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTVTATKWWPGDLGRSATHALILAQLICSGARRGMHAFIVPVRSLQDHTPLPGITIGDIGPKMGLQHIDNGFLKMDHVRVPRENMLSRFAQVLPDGAYIKLGTAQSNYLGMLVTRVHLLLGAILSPLQKACVIATRYSVIRHQCRLRPSDPEVKILEHQTQQQKLFPQLAMCYAFHFLATGLLEFFQQAYKNILDRDFTLLPELHALSTGTKAMMSDFCTQGAEQCRRACGGHGYSKLSGLPSLVTSVTASCTYEGENTVLYLQVARFLVKSCLQAQGFPGSTSQRSLPRSVSYLALPDLARCPAQTAADFFCPALYTAAWAHVAARLTKDSVHHLQALRQSGADEHEAWNQTTIIHLQAAKAHCYYISVKSFKEALEKLENEPAIQQVLKRLCDLHALHGILTNSGDFLHDGFLSGAQVDMARTAYMDLLPLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFEWAQRSPTNTQENPAYKKYIQPLLQSWRSNL
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Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (PubMed:9218493). Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity). (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2 Homodimer. Liver and kidney. Belongs to the acyl-CoA oxidase family.
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P97562
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MGSPMHRVSLGDHWSWQVHPDIDSERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSDPVFNLKKLYFMTREELYEDAIQKRFHLEKLAWSLGWSEDGPERIYANRVLDGNVNLSLHGVAMNAIRSLGSDEQIAKWGQLCKNFQIITTYAQTELGHGTYLQGLETEATYDEARQELVIHSPTMTSTKWWPGDLGWSVTHAVVLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGLEHIDNGFLQLNHVRVPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLCKGILPSLQKACIIATRYSVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYAFHFTATSLSEFFHSSYSAILKRDFSLLPELHALSTGMKATFADFCAQGAEICRRACGGHGYSKLSGLPTLVARATASCTYEGENTVLYLQVARFLMKSYLQAQASPGATPQKPLPQSVMYIATQRPARCSAQTAADFRCPDVYTTAWAYVSTRLIRDAAHRTQTLMKSGVDQHDAWNQTTVIHLQAAKAHCYFITVKNFKEAVEKLDKEPEIQRVLQRLCDLYALHGVLTNSGDFLHDGFLSGAQVDMAREAFLDLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYERLFEWAQKYPANTQENPAYKKYIRPLMLGWRHKM
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Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycoprostanic acids (PubMed:8947475, PubMed:1400324). Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (PubMed:1400324). (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2 Homodimer. Most abundant in liver. Also expressed in kidney. Not present in any other tissues tested. Belongs to the acyl-CoA oxidase family.
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Q6C248
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MNPNNTGTIEINGKEYNTFTEPPVAMAQERAKTSFPVREMTYFLDGGEKNTLKNEQIMEEIERDPLFNNDNYYDLNKEQIRELTMERVAKLSLFVRDQPEDDIKKRFALIGIADMGTYTRLGVHYGLFFGAVRGTGTAEQFGHWISKGAGDLRKFYGCFSMTELGHGSNLAGLETTAIYDEETDEFIINTPHIAATKWWIGGAAHTATHTVVFARLIVKGKDYGVKTFVVQLRNINDHSLKVGISIGDIGKKMGRDGIDNGWIQFTNVRIPRQNLLMKYTKVDREGNVTQPPLAQLTYGSLITGRVSMASDSHQVGKRFITIALRYACIRRQFSTTPGQPETKIIDYPYHQRRLLPLLAYVYALKMTADEVGALFSRTMLKMDDLKPDDKAGLNEVVSDVKELFSVSAGLKAFSTWACADVIDKTRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNILTLSAGRALIQSAVALRKGEPVGNAVSYLKRYKDLANAKLNGRSLTDPKVLVEAWEVAAGNIINRATDQYEKLIGEGLNADQAFEVLSQQRFQAAKVHTRRHLIAAFFSRIDTEAGEAIKQPLLNLALLFALWSIEEDSGLFLREGFLEPKDIDTVTELVNKYCTTVREEVIGYTDAFNLSDYFINAPIGCYDGDAYRHYFQKVNEQNPARDPRPPYYASTLKPFLFREEEDDDICELDEE
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Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Heteropentamer composed of five different subunits. Belongs to the acyl-CoA oxidase family.
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Q9M7X6
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MTKEPIYSPRMLHRDPDSPRPVLPTQLTSSTLRCSQFQTNVFCLRERDLLERFTSEVAQLQGRGESREFSFLLSHQLAEDLGKAFTEKAMLQTILDAEAKLPTGSVKDVLGLVRSMYALISLEEDPSLLRYGYLSQDNVGDVRREVSKLCGELRPHALALVTSFGIPDSFLSPIAFNWVEANTWSSV
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a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 Belongs to the acyl-CoA oxidase family.
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Q96AJ8
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MASTVEGGDTALLPEFPRGPLDAYRARASFSWKELALFTEGEGMLRFKKTIFSALENDPLFARSPGADLSLEKYRELNFLRCKRIFEYDFLSVEDMFKSPLKVPALIQCLGMYDSSLAAKYLLHSLVFGSAVYSSGSERHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRTTAHYDPATEEFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLCVPGDQCHGLHPFIVQIRDPKTLLPMPGVMVGDIGKKLGQNGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSPFKDVRQRFGASLGSLSSGRVSIVSLAILNLKLAVAIALRFSATRRQFGPTEEEEIPVLEYPMQQWRLLPYLAAVYALDHFSKSLFLDLVELQRGLASGDRSARQAELGREIHALASASKPLASWTTQQGIQECREACGGHGYLAMNRLGVLRDDNDPNCTYEGDNNILLQQTSNYLLGLLAHQVHDGACFRSPLKSVDFLDAYPGILDQKFEVSSVADCLDSAVALAAYKWLVCYLLRETYQKLNQEKRSGSSDFEARNKCQVSHGRPLALAFVELTVVQRFHEHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYRGGYFSGEQAGEVLESAVLALCSQLKDDAVALVDVIAPPDFVLDSPIGRADGELYKNLWGAVLQESKVLERASWWPEFSVNKPVIGSLKSKL
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Oxidizes the CoA-esters of 2-methyl-branched fatty acids. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Belongs to the acyl-CoA oxidase family.
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Q80UQ0
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MGSLPEEKDSALWSDTPKGPLSAYRARASFNSGELLLFWDGQDVIHFKKTIFSTLENDPLFARSYGADLPLEKLRELNFLRCKRVFEYGFFKVEELLKNPLKILVLINCLGMYDWSLANKCVLHMLVFGTTVFVSGSEKHFKYLEKIYSLEIFGCFALTELSHGSNTKAMRTTAHYDPDTQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYMPDGQCHGLHSFLVQIRDTKTLLPMTGVMVGDIGKKLGQNGLDNGFAMFNKVRIPRQNLLDRTGNITSEGTYNSPFKDVRQRLGASLGSLSSGRISIISMSVVNLKLAVSIAIRFSATRCQFGPTDKEEIPVLEYPLQQWRILPYLAAAYALDHFSKTIFMDLIEVQSARLRGDHSDQQAELGREIHALASAGKPLASWTAQRGIQECREACGGHGYLAMNRFGDLRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEPPLQDGAHFTSPLKTVDFLEAYPGILGQKFLGSSKADWMDSAAPLAAYRWLVCYLLQESHRRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHIHSSGLSPSLRTVLGRLSTLYGLWCLSQHMALLYRGGYISGEQTGRAMEDAILTLCEQLKDDAVALVDVIAPSDFVLNSPIAKADGELYKNLWAAVLQQNGVLERAAWWPEFSANKSVADRLKSQL
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Oxidizes the CoA-esters of 2-methyl-branched fatty acids. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Belongs to the acyl-CoA oxidase family.
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Q5RAU0
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MASTVEGGDTALLPEFPGGPLDAYRARASFSWKELALFTEGEDMLRFKKTIFSALENDPLFARSPGADLSLEKYRELNFLRCRRIFEYDFLSVEDMFKSPLKVLTLIQCLGMYDSSLAAKYLIHSLVFGSAIYSSGSERHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRTTAHYDPATEEFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLYVPGDQCHGLHPFIVQIRDSKTLLPMPGVMVGDIGKKLGQNGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSSFKDVRQHFGATLGSLSWSRVSIVSLAILNLKLAVAIALRFSATRRQFGPTEEEEIPVLEYPMQQWRLLPYLAAIYALDHFSKSLFLDLMELQQGLASGDRSARQAELGREIHALASASKPLASWTTQQGIQECREACGGHGYLAMNRLGVLRDDNDPNCTYEGDNNILLQQTSNYLLGLLAHQVQDGACFRSPLKSVDFLDAYPGILDQKFEVSSVADCLDSAVALAAYKWLVCYLLRETYQKLNQEKRSGSSDFEARNKCQVSHGRPLALAFVELTVVQRFHEHVHQPCVPPSLRAVLGRLSALYALWSLSRHAALLYRGGYFSGEQAGEVLESAVLALCSQLKDDAVALVDVIAPPDFILDSPIGRADGELYKNLWGAILQESKALERASWWPEFSVNKPVIGSLKSKL
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Oxidizes the CoA-esters of 2-methyl-branched fatty acids. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Belongs to the acyl-CoA oxidase family.
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Q63448
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MGSSSERRDSVLWSDIPKGPLSAYRARASFNSKELMLFWDGQDVLDFKKTIFSTLENDPLFARPFGADLPLEKERELNFLRCKRVFEYGFFNAEDMLKNPLKILVLMNCLGMYDWSLANKCVLHMLVFGSTIIGSGSEHHFKYLEKIYNLEIFGCFALTELSHGSNTKAMRTTAHYDPATQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYTPDGQCRGLHSFLVQIRDPKTLLPMPGVMVGDMGKKLGQNGLDNGFAMFHKVRIPRQNLLDRTGNVTSEGHYHTPFKDVRQRLGASLGSLSSGRISIISISVVNLKLAVIIAIRFSATRRQFGPTDKEEIPVLEYPLQQWRLLPYLAAAYALDHFSKTIFLDLIELQRAGKVGTTVTGRQSSGREIHALASAGKPLASWTAQRGIQECREVVGGHGYLAMNRFGELRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEHPLQDGAHFTSPLKTVNFLEAYPGILGQKFMASSKADWLDSEAPLAAYRWLVCYLLRESHQRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHTHSSSVPPSLRTVLGRLSMLYGLWCLSQHTALLYRGGYISGEQTGKAMEDAILMLCVQLKDDAVALVDAIAPSDFVLGSPIGRADGELYKNLWAAVLQQSGVLERAAWWPEFTANKSVANRLKSQL
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Oxidizes the CoA-esters of 2-methyl-branched fatty acids. a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2 (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2 O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2 hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2 hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2 Lipid metabolism; peroxisomal fatty acid beta-oxidation. Most abundant in liver, kidney, lung, and testis. Present in all tissues tested. Belongs to the acyl-CoA oxidase family.
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