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Context: to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing an oscillation with a period of around 500 kb in guanine and cytosine content ( gc % ) is observed in the dna sequence of human chromosome 21. this oscillation is localized in the rightmost one - eighth region of the chromosome, from 43. 5 mb to 46. 5 mb. five cycles of oscillation are observed in this region with six gc - rich peaks and five gc - poor valleys. the gc - poor valleys comprise regions with low density of cpg islands and, alternating between the two dna strands, low gene density regions. consequently, the long - range oscillation of gc % result in spacing patterns of both cpg island density, and to a lesser extent, gene densities. ##tes, i. e., genes are unlinked. an exception to this rule would include traits that are sex - linked. test crosses can be performed to experimentally determine the underlying genotype of an organism with a dominant phenotype. a punnett square can be used to predict the results of a test cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna so on. these plastic casings are usually a composite material made up of a thermoplastic matrix such as acrylonitrile butadiene styrene ( abs ) in which calcium carbonate chalk, talc, glass fibers or carbon fibers have been added for added strength, bulk, or electrostatic dispersion. these additions may be termed reinforcing fibers, or dispersants, depending on their purpose. = = = polymers = = = polymers are chemical compounds made up of a large number of identical components linked together like chains. polymers are the raw materials ( the resins ) used to make what are commonly called plastics and rubber. plastics and rubber are the final product, created after one or more polymers or additives have been added to a resin during processing, which is then shaped into a final form. plastics in former and in current widespread use include polyethylene, polypropylene, polyvinyl chloride ( pvc ), polystyrene, nylons, polyesters, acrylics, polyurethanes, and polycarbonates. rubbers include natural rubber, styrene - butadiene rubber, chloroprene, and butadiene rubber. plastics are generally classified as commodity, specialty and engineering plastics. polyvinyl chloride ( pvc ) is widely used, inexpensive, and annual production quantities are large. it lends itself to a vast array of applications, from artificial leather to electrical insulation and cabling, packaging, and containers. its fabrication and processing are simple and well - established. the versatility of pvc is due to the wide range of plasticisers and other additives that it accepts. the term " additives " in polymer science refers to the chemicals and compounds added to the polymer base to modify its material properties. polycarbonate would be normally considered an engineering plastic ( other examples include peek, abs ). such plastics are valued for their superior strengths and other special material properties. they are usually not used for disposable applications, unlike commodity plastics. specialty plastics are materials with unique characteristics, such as ultra - high strength, electrical conductivity, electro - fluorescence, high thermal stability, etc. the dividing lines between the various types of plastics is not based on material but rather on their properties and applications. for example, polyethylene ( pe ) is a cheap, low friction polymer commonly used to make disposable bags for shopping and trash, and is considered a commodity plastic, whereas medium - cell - culture scaffolds the material needed for each application is different, and dependent on the desired mechanical properties of the material. tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone ( 100 - 150 mpa ), which is much higher compared to a scaffold for skin regeneration. there are a few versatile synthetic materials used for many different scaffold applications. one of these commonly used materials is polylactic acid ( pla ), a synthetic polymer. pla – polylactic acid. this is a polyester which degrades within the human body to form lactic acid, a naturally occurring chemical which is easily removed from the body. similar materials are polyglycolic acid ( pga ) and polycaprolactone ( pcl ) : their degradation mechanism is similar to that of pla, but pcl degrades slower and pga degrades faster. pla is commonly combined with pga to create poly - lactic - co - glycolic acid ( plga ). this is especially useful because the degradation of plga can be tailored by altering the weight percentages of pla and pga : more pla – slower degradation, more pga – faster degradation. this tunability, along with its biocompatibility, makes it an extremely useful material for scaffold creation. scaffolds may also be constructed from natural materials : in particular different derivatives of the extracellular matrix have been studied to evaluate their ability to support cell growth. protein based materials – such as collagen, or fibrin, and polysaccharidic materials - like chitosan or glycosaminoglycans ( gags ), have all proved suitable in terms of cell compatibility. among gags, hyaluronic acid, possibly in combination with cross linking agents ( e. g. glutaraldehyde, water - soluble carbodiimide, etc. ), is one of the possible choices as scaffold material. due to the covalent attachment of thiol groups to these polymers, they can crosslink via disulfide bond formation. the use of thiolated polymers ( thiomers ) as scaffold material for tissue engineering was initially introduced at the 4th central european symposium on pharmaceutical technology in vienna 2001. as thiomers are biocompatible, exhibit cellular mimicking properties and efficiently support proliferation and differentiation of various cell types, some properties of the nuclear matter as revealed by cherenkov gluons are discussed. is opened and the dna is purified. the gene is separated by using restriction enzymes to cut the dna into fragments or polymerase chain reaction ( pcr ) to amplify up the gene segment. these segments can then be extracted through gel electrophoresis. if the chosen gene or the donor organism ' s genome has been well studied it may already be accessible from a genetic library. if the dna sequence is known, but no copies of the gene are available, it can also be artificially synthesised. once isolated the gene is ligated into a plasmid that is then inserted into a bacterium. the plasmid is replicated when the bacteria divide, ensuring unlimited copies of the gene are available. the rk2 plasmid is notable for its ability to replicate in a wide variety of single - celled organisms, which makes it suitable as a genetic engineering tool. before the gene is inserted into the target organism it must be combined with other genetic elements. these include a promoter and terminator region, which initiate and end transcription. a selectable marker gene is added, which in most cases confers antibiotic resistance, so researchers can easily determine which cells have been successfully transformed. the gene can also be modified at this stage for better expression or effectiveness. these manipulations are carried out using recombinant dna techniques, such as restriction digests, ligations and molecular cloning. = = = inserting dna into the host genome = = = there are a number of techniques used to insert genetic material into the host genome. some bacteria can naturally take up foreign dna. this ability can be induced in other bacteria via stress ( e. g. thermal or electric shock ), which increases the cell membrane ' s permeability to dna ; up - taken dna can either integrate with the genome or exist as extrachromosomal dna. dna is generally inserted into animal cells using microinjection, where it can be injected through the cell ' s nuclear envelope directly into the nucleus, or through the use of viral vectors. plant genomes can be engineered by physical methods or by use of agrobacterium for the delivery of sequences hosted in t - dna binary vectors. in plants the dna is often inserted using agrobacterium - mediated transformation, taking advantage of the agrobacteriums t - dna sequence that allows natural insertion of genetic material into plant cells. other methods include biolistics, where particles of gold or tungsten are coated with dna and then shot into the monocrystalline silicon neutron beam window is one of the key components of neutron spectrometers and thin circular plate. monocrystalline silicon is a brittle material and its strength is not constant but is consistent with the weibull distribution. the window is designed not simply through the average strength, but according to the survival rate. bending deformation is the main form of the window, so dangerous parts of the neutron beam window is stress - linearized to the combination of membrane stress and bending stress. according to the weibull distribution of bending strength of monocrystalline silicon based on a large number of experimental data, finally the optimized neutron beam window is 1. 5mm thick. its survival rate is 0. 9994 and its transmittance is 0. 98447 ; it meets both physical requirements and the mechanical strength. industry is making composite materials. these are structured materials composed of two or more macroscopic phases. applications range from structural elements such as steel - reinforced concrete, to the thermal insulating tiles, which play a key and integral role in nasa ' s space shuttle thermal protection system, which is used to protect the surface of the shuttle from the heat of re - entry into the earth ' s atmosphere. one example is reinforced carbon - carbon ( rcc ), the light gray material, which withstands re - entry temperatures up to 1, 510 °c ( 2, 750 °f ) and protects the space shuttle ' s wing leading edges and nose cap. rcc is a laminated composite material made from graphite rayon cloth and impregnated with a phenolic resin. after curing at high temperature in an autoclave, the laminate is pyrolized to convert the resin to carbon, impregnated with furfuryl alcohol in a vacuum chamber, and cured - pyrolized to convert the furfuryl alcohol to carbon. to provide oxidation resistance for reusability, the outer layers of the rcc are converted to silicon carbide. other examples can be seen in the " plastic " casings of television sets, cell - phones and so on. these plastic casings are usually a composite material made up of a thermoplastic matrix such as acrylonitrile butadiene styrene ( abs ) in which calcium carbonate chalk, talc, glass fibers or carbon fibers have been added for added strength, bulk, or electrostatic dispersion. these additions may be termed reinforcing fibers, or dispersants, depending on their purpose. = = = polymers = = = polymers are chemical compounds made up of a large number of identical components linked together like chains. polymers are the raw materials ( the resins ) used to make what are commonly called plastics and rubber. plastics and rubber are the final product, created after one or more polymers or additives have been added to a resin during processing, which is then shaped into a final form. plastics in former and in current widespread use include polyethylene, polypropylene, polyvinyl chloride ( pvc ), polystyrene, nylons, polyesters, acrylics, polyurethanes, and polycarbonates. rubbers include natural rubber, styrene - butadiene rubber, chloroprene, and butadiene rubber. plastics are generally classified as commodity Question: Chromosomes consist of what material made up of strings of dna? A) mitochondria B) chromatin C) gray matter D) rna	B) chromatin
Context: electric motors, servo - mechanisms, and other electrical systems in conjunction with special software. a common example of a mechatronics system is a cd - rom drive. mechanical systems open and close the drive, spin the cd and move the laser, while an optical system reads the data on the cd and converts it to bits. integrated software controls the process and communicates the contents of the cd to the computer. robotics is the application of mechatronics to create robots, which are often used in industry to perform tasks that are dangerous, unpleasant, or repetitive. these robots may be of any shape and size, but all are preprogrammed and interact physically with the world. to create a robot, an engineer typically employs kinematics ( to determine the robot ' s range of motion ) and mechanics ( to determine the stresses within the robot ). robots are used extensively in industrial automation engineering. they allow businesses to save money on labor, perform tasks that are either too dangerous or too precise for humans to perform them economically, and to ensure better quality. many companies employ assembly lines of robots, especially in automotive industries and some factories are so robotized that they can run by themselves. outside the factory, robots have been employed in bomb disposal, space exploration, and many other fields. robots are also sold for various residential applications, from recreation to domestic applications. = = = structural analysis = = = structural analysis is the branch of mechanical engineering ( and also civil engineering ) devoted to examining why and how objects fail and to fix the objects and their performance. structural failures occur in two general modes : static failure, and fatigue failure. static structural failure occurs when, upon being loaded ( having a force applied ) the object being analyzed either breaks or is deformed plastically, depending on the criterion for failure. fatigue failure occurs when an object fails after a number of repeated loading and unloading cycles. fatigue failure occurs because of imperfections in the object : a microscopic crack on the surface of the object, for instance, will grow slightly with each cycle ( propagation ) until the crack is large enough to cause ultimate failure. failure is not simply defined as when a part breaks, however ; it is defined as when a part does not operate as intended. some systems, such as the perforated top sections of some plastic bags, are designed to break. if these systems do not break, failure analysis might be employed to determine the cause. structural analysis is often used by mechanical engineers after a failure has occurred, or when designing to prevent failure which could be used as tools, primarily in the form of choppers or scrapers. these tools greatly aided the early humans in their hunter - gatherer lifestyle to perform a variety of tasks including butchering carcasses ( and breaking bones to get at the marrow ) ; chopping wood ; cracking open nuts ; skinning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures three of what is called the six simple machines, from which all machines are based. these machines are the inclined plane, the wedge, and the lever, which allowed the ancient egyptians to move millions of limestone blocks which weighed approximately 3. 5 tons ( 7, 000 lbs. ) each into place to create structures like the great pyramid of giza, which is 481 feet ( 147 meters ) high. they also made writing medium similar to paper from papyrus, which joshua mark states is the foundation for modern paper. papyrus is a plant ( cyperus papyrus ) which grew in plentiful amounts in the egyptian delta and throughout the nile river valley during ancient times. the papyrus was harvested by field workers and brought to processing centers where it was cut into thin strips. the strips were then laid - out side by side and covered in plant resin. the second layer of strips was laid on perpendicularly, then both pressed together until the sheet was dry. the sheets were then joined to form a roll and later used for writing. egyptian society made several significant advances during dynastic periods in many areas of technology. according to hossam elanzeery, they were the first civilization to use timekeeping devices such as sundials, shadow clocks, and obelisks and successfully leveraged their knowledge of astronomy to create a calendar model that society still uses today. they developed shipbuilding technology that saw them progress from papyrus reed vessels to cedar wood ships while also pioneering the use of rope trusses and stem - mounted rudders. the egyptians also used their knowledge of anatomy to lay the foundation for many modern medical techniques and practiced the earliest known version of neuroscience. elanzeery also states that they used and furthered mathematical science, as evidenced in the building of the pyramids. ancient egyptians also invented and pioneered many food technologies that have become the basis of modern food technology processes. based on paintings and reliefs found in tombs, as well as archaeological artifacts, scholars like paul t nicholson believe that the ancient egyptians established systematic farming practices, engaged in cereal processing, brewed beer and baked bread, processed meat, practiced viticulture and created the basis for modern wine production, and created condiments to complement, preserve and mask the flavors of their food. = = = = indus valley = = = = the indus valley civilization, situated in a resource - rich area ( in modern pakistan and northwestern india ), is notable for its early application of city planning, sanitation technologies, and plumbing. indus valley construction and architecture, called ' vaastu . batching is the process of weighing the oxides according to recipes, and preparing them for mixing and drying. mixing occurs after batching and is performed with various machines, such as dry mixing ribbon mixers ( a type of cement mixer ), resonantacoustic mixers, mueller mixers, and pug mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, heat removes water. this step needs careful control, as rapid heating causes cracks and surface defects. the dried part is smaller than the green part, and is brittle, necessitating careful handling, since a small impact will cause crumbling and breaking. sintering is where the dried parts pass through a controlled heating process, and the oxides are chemically changed to cause bonding and densification. the fired part will be smaller than the dried part. = = forming methods = = ceramic forming techniques include throwing, slipcasting, tape casting, freeze - casting, injection molding, dry pressing, isostatic pressing, hot isostatic pressing ( hip ), 3d printing and others. methods for forming ceramic powders into complex shapes are desirable in many areas of technology. such methods are required for producing advanced, high - temperature structural parts such as heat engine components and turbines. materials other than ceramics which are used in these processes may include : wood, metal, water, plaster and epoxy — most of which will be eliminated upon firing. a ceramic - filled epoxy, such as martyte, is sometimes used to protect structural steel under conditions of rocket exhaust impingement. these forming techniques are well known for providing tools and other components with dimensional stability, surface quality temperature changes up to 1000 °c. = = processing steps = = the traditional ceramic process generally follows this sequence : milling → batching → mixing → forming → drying → firing → assembly. milling is the process by which materials are reduced from a large size to a smaller size. milling may involve breaking up cemented material ( in which case individual particles retain their shape ) or pulverization ( which involves grinding the particles themselves to a smaller size ). milling is generally done by mechanical means, including attrition ( which is particle - to - particle collision that results in agglomerate break up or particle shearing ), compression ( which applies a forces that results in fracturing ), and impact ( which employs a milling medium or the particles themselves to cause fracturing ). attrition milling equipment includes the wet scrubber ( also called the planetary mill or wet attrition mill ), which has paddles in water creating vortexes in which the material collides and break up. compression mills include the jaw crusher, roller crusher and cone crusher. impact mills include the ball mill, which has media that tumble and fracture the material, or the resonantacoustic mixer. shaft impactors cause particle - to particle attrition and compression. batching is the process of weighing the oxides according to recipes, and preparing them for mixing and drying. mixing occurs after batching and is performed with various machines, such as dry mixing ribbon mixers ( a type of cement mixer ), resonantacoustic mixers, mueller mixers, and pug mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, which applies a forces that results in fracturing ), and impact ( which employs a milling medium or the particles themselves to cause fracturing ). attrition milling equipment includes the wet scrubber ( also called the planetary mill or wet attrition mill ), which has paddles in water creating vortexes in which the material collides and break up. compression mills include the jaw crusher, roller crusher and cone crusher. impact mills include the ball mill, which has media that tumble and fracture the material, or the resonantacoustic mixer. shaft impactors cause particle - to particle attrition and compression. batching is the process of weighing the oxides according to recipes, and preparing them for mixing and drying. mixing occurs after batching and is performed with various machines, such as dry mixing ribbon mixers ( a type of cement mixer ), resonantacoustic mixers, mueller mixers, and pug mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, heat removes water. this step needs careful control, as rapid heating causes cracks and surface defects. the dried part is smaller than the green part, and is brittle, necessitating careful handling, since a small impact will cause crumbling and breaking. sintering is where the dried parts pass through a controlled heating process, and the oxides are chemically changed to cause bonding and densification. the fired part will be smaller than the dried part. = = forming methods = = ceramic forming techniques include throwing, slipcasting, tape casting, freeze - casting, injection molding, dry pressing, isostatic pressing, hot isostatic pressing the material collides and break up. compression mills include the jaw crusher, roller crusher and cone crusher. impact mills include the ball mill, which has media that tumble and fracture the material, or the resonantacoustic mixer. shaft impactors cause particle - to particle attrition and compression. batching is the process of weighing the oxides according to recipes, and preparing them for mixing and drying. mixing occurs after batching and is performed with various machines, such as dry mixing ribbon mixers ( a type of cement mixer ), resonantacoustic mixers, mueller mixers, and pug mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, heat removes water. this step needs careful control, as rapid heating causes cracks and surface defects. the dried part is smaller than the green part, and is brittle, necessitating careful handling, since a small impact will cause crumbling and breaking. sintering is where the dried parts pass through a controlled heating process, and the oxides are chemically changed to cause bonding and densification. the fired part will be smaller than the dried part. = = forming methods = = ceramic forming techniques include throwing, slipcasting, tape casting, freeze - casting, injection molding, dry pressing, isostatic pressing, hot isostatic pressing ( hip ), 3d printing and others. methods for forming ceramic powders into complex shapes are desirable in many areas of technology. such methods are required for producing advanced, high - temperature structural parts such as heat engine components and turbines. materials other than ceramics which are used in these processes may include : wood, metal, casting, also called the lost wax process, die casting, centrifugal casting, both vertical and horizontal, and continuous castings. each of these forms has advantages for certain metals and applications considering factors like magnetism and corrosion. forging – a red - hot billet is hammered into shape. rolling – a billet is passed through successively narrower rollers to create a sheet. extrusion – a hot and malleable metal is forced under pressure through a die, which shapes it before it cools. machining – lathes, milling machines and drills cut the cold metal to shape. sintering – a powdered metal is heated in a non - oxidizing environment after being compressed into a die. fabrication – sheets of metal are cut with guillotines or gas cutters and bent and welded into structural shape. laser cladding – metallic powder is blown through a movable laser beam ( e. g. mounted on a nc 5 - axis machine ). the resulting melted metal reaches a substrate to form a melt pool. by moving the laser head, it is possible to stack the tracks and build up a three - dimensional piece. 3d printing – sintering or melting amorphous powder metal in a 3d space to make any object to shape. cold - working processes, in which the product ' s shape is altered by rolling, fabrication or other processes, while the product is cold, can increase the strength of the product by a process called work hardening. work hardening creates microscopic defects in the metal, which resist further changes of shape. = = = heat treatment = = = metals can be heat - treated to alter the properties of strength, ductility, toughness, hardness and resistance to corrosion. common heat treatment processes include annealing, precipitation strengthening, quenching, and tempering : annealing process softens the metal by heating it and then allowing it to cool very slowly, which gets rid of stresses in the metal and makes the grain structure large and soft - edged so that, when the metal is hit or stressed it dents or perhaps bends, rather than breaking ; it is also easier to sand, grind, or cut annealed metal. quenching is the process of cooling metal very quickly after heating, thus " freezing " the metal ' s molecules in the very hard martensite form, which makes the metal harder. tempering relieves stresses in the metal that were caused by the hardening process ; tempering makes the metal less hard while making it better able to sustain ; and the wafer surfaces are sufficiently clean. the most stringent criteria for wafer bonding is usually the direct fusion wafer bonding since even one or more small particulates can render the bonding unsuccessful. in comparison, wafer bonding methods that use intermediary layers are often far more forgiving. both bulk and surface silicon micromachining are used in the industrial production of sensors, ink - jet nozzles, and other devices. but in many cases the distinction between these two has diminished. a new etching technology, deep reactive - ion etching, has made it possible to combine good performance typical of bulk micromachining with comb structures and in - plane operation typical of surface micromachining. while it is common in surface micromachining to have structural layer thickness in the range of 2 μm, in har silicon micromachining the thickness can be from 10 to 100 μm. the materials commonly used in har silicon micromachining are thick polycrystalline silicon, known as epi - poly, and bonded silicon - on - insulator ( soi ) wafers although processes for bulk silicon wafer also have been created ( scream ). bonding a second wafer by glass frit bonding, anodic bonding or alloy bonding is used to protect the mems structures. integrated circuits are typically not combined with har silicon micromachining. = = applications = = some common commercial applications of mems include : inkjet printers, which use piezoelectrics or thermal bubble ejection to deposit ink on paper. accelerometers in modern cars for a large number of purposes including airbag deployment and electronic stability control. inertial measurement units ( imus ) : mems accelerometers. mems gyroscopes in remote controlled, or autonomous, helicopters, planes and multirotors ( also known as drones ), used for automatically sensing and balancing flying characteristics of roll, pitch and yaw. mems magnetic field sensor ( magnetometer ) may also be incorporated in such devices to provide directional heading. mems inertial navigation systems ( inss ) of modern cars, airplanes, submarines and other vehicles to detect yaw, pitch, and roll ; for example, the autopilot of an airplane. accelerometers in consumer electronics devices such as game controllers ( nintendo wii ), personal media players / cell phones ( virtually all smartphones, various htc pda models ), augmented in which case individual particles retain their shape ) or pulverization ( which involves grinding the particles themselves to a smaller size ). milling is generally done by mechanical means, including attrition ( which is particle - to - particle collision that results in agglomerate break up or particle shearing ), compression ( which applies a forces that results in fracturing ), and impact ( which employs a milling medium or the particles themselves to cause fracturing ). attrition milling equipment includes the wet scrubber ( also called the planetary mill or wet attrition mill ), which has paddles in water creating vortexes in which the material collides and break up. compression mills include the jaw crusher, roller crusher and cone crusher. impact mills include the ball mill, which has media that tumble and fracture the material, or the resonantacoustic mixer. shaft impactors cause particle - to particle attrition and compression. batching is the process of weighing the oxides according to recipes, and preparing them for mixing and drying. mixing occurs after batching and is performed with various machines, such as dry mixing ribbon mixers ( a type of cement mixer ), resonantacoustic mixers, mueller mixers, and pug mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, heat removes water. this step needs careful control, as rapid heating causes cracks and surface defects. the dried part is smaller than the green part, and is brittle, necessitating careful handling, since a small impact will cause crumbling and breaking. sintering is where the dried parts pass through a controlled heating process, and Question: Are scissors simple or compound machines? A) lever B) neither C) compound D) simple	C) compound
Context: in isotope dating states : there are only three quite technical instances where a half - life changes, and these do not affect the dating methods : " only one technical exception occurs under terrestrial conditions, and this is not for an isotope used for dating.... the artificially - produced isotope, beryllium - 7 has been shown to change by up to 1. 5 %, depending on its chemical environment.... heavier atoms are even less subject to these minute changes, so the dates of rocks made by electron - capture decays would only be off by at most a few hundredths of a percent. " "... another case is material inside of stars, which is in a plasma state where electrons are not bound to atoms. in the extremely hot stellar environment, a completely different kind of decay can occur. ' bound - state beta decay ' occurs when the nucleus emits an electron into a bound electronic state close to the nucleus.... all normal matter, such as everything on earth, the moon, meteorites, etc. has electrons in normal positions, so these instances never apply to rocks, or anything colder than several hundred thousand degrees. " " the last case also involves very fast - moving matter. it has been demonstrated by atomic clocks in very fast spacecraft. these atomic clocks slow down very slightly ( only a second or so per year ) as predicted by einstein ' s theory of relativity. no rocks in our solar system are going fast enough to make a noticeable change in their dates. " = = = = radiohaloes = = = = in the 1970s, young earth creationist robert v. gentry proposed that radiohaloes in certain granites represented evidence for the earth being created instantaneously rather than gradually. this idea has been criticized by physicists and geologists on many grounds including that the rocks gentry studied were not primordial and that the radionuclides in question need not have been in the rocks initially. thomas a. baillieul, a geologist and retired senior environmental scientist with the united states department of energy, disputed gentry ' s claims in an article entitled, " ' polonium haloes ' refuted : a review of ' radioactive halos in a radio - chronological and cosmological perspective ' by robert v. gentry. " baillieul noted that gentry was a physicist with no background in geology and given the absence of this background, gentry had misrepresented the geological context from which the specimens were collected. additionally, he noted that gentry relied on research from the hazard. many of the scientists working on radioactivity died of cancer as a result of their exposure. radioactive patent medicines mostly disappeared, but other applications of radioactive materials persisted, such as the use of radium salts to produce glowing dials on meters. as the atom came to be better understood, the nature of radioactivity became clearer. some larger atomic nuclei are unstable, and so decay ( release matter or energy ) after a random interval. the three forms of radiation that becquerel and the curies discovered are also more fully understood. alpha decay is when a nucleus releases an alpha particle, which is two protons and two neutrons, equivalent to a helium nucleus. beta decay is the release of a beta particle, a high - energy electron. gamma decay releases gamma rays, which unlike alpha and beta radiation are not matter but electromagnetic radiation of very high frequency, and therefore energy. this type of radiation is the most dangerous and most difficult to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. if there are enough immediate decays to carry on the chain reaction, the mass is said to be prompt critical, and the energy release will grow rapidly and uncontrollably, usually leading to an explosion. when discovered on the eve of world war ii, this insight led multiple countries to begin programs investigating the possibility quack medicine ( as had the discoveries of electricity and magnetism, earlier ), and a number of patent medicines and treatments involving radioactivity were put forward. gradually it was realized that the radiation produced by radioactive decay was ionizing radiation, and that even quantities too small to burn could pose a severe long - term hazard. many of the scientists working on radioactivity died of cancer as a result of their exposure. radioactive patent medicines mostly disappeared, but other applications of radioactive materials persisted, such as the use of radium salts to produce glowing dials on meters. as the atom came to be better understood, the nature of radioactivity became clearer. some larger atomic nuclei are unstable, and so decay ( release matter or energy ) after a random interval. the three forms of radiation that becquerel and the curies discovered are also more fully understood. alpha decay is when a nucleus releases an alpha particle, which is two protons and two neutrons, equivalent to a helium nucleus. beta decay is the release of a beta particle, a high - energy electron. gamma decay releases gamma rays, which unlike alpha and beta radiation are not matter but electromagnetic radiation of very high frequency, and therefore energy. this type of radiation is the most dangerous and most difficult to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. the fundamental constants could not influence different elements uniformly, and a comparison between each of the elements ' resulting unique chronological timescales would then give inconsistent time estimates. in refutation of young earth claims of inconstant decay rates affecting the reliability of radiometric dating, roger c. wiens, a physicist specializing in isotope dating states : there are only three quite technical instances where a half - life changes, and these do not affect the dating methods : " only one technical exception occurs under terrestrial conditions, and this is not for an isotope used for dating.... the artificially - produced isotope, beryllium - 7 has been shown to change by up to 1. 5 %, depending on its chemical environment.... heavier atoms are even less subject to these minute changes, so the dates of rocks made by electron - capture decays would only be off by at most a few hundredths of a percent. " "... another case is material inside of stars, which is in a plasma state where electrons are not bound to atoms. in the extremely hot stellar environment, a completely different kind of decay can occur. ' bound - state beta decay ' occurs when the nucleus emits an electron into a bound electronic state close to the nucleus.... all normal matter, such as everything on earth, the moon, meteorites, etc. has electrons in normal positions, so these instances never apply to rocks, or anything colder than several hundred thousand degrees. " " the last case also involves very fast - moving matter. it has been demonstrated by atomic clocks in very fast spacecraft. these atomic clocks slow down very slightly ( only a second or so per year ) as predicted by einstein ' s theory of relativity. no rocks in our solar system are going fast enough to make a noticeable change in their dates. " = = = = radiohaloes = = = = in the 1970s, young earth creationist robert v. gentry proposed that radiohaloes in certain granites represented evidence for the earth being created instantaneously rather than gradually. this idea has been criticized by physicists and geologists on many grounds including that the rocks gentry studied were not primordial and that the radionuclides in question need not have been in the rocks initially. thomas a. baillieul, a geologist and retired senior environmental scientist with the united states department of energy, disputed gentry ' s claims in an article entitled, " ' polonium haloes ' refuted : a review of ' radioactive halos in a radio the first three greek letters. some of these kinds of radiation could pass through ordinary matter, and all of them could be harmful in large amounts. all of the early researchers received various radiation burns, much like sunburn, and thought little of it. the new phenomenon of radioactivity was seized upon by the manufacturers of quack medicine ( as had the discoveries of electricity and magnetism, earlier ), and a number of patent medicines and treatments involving radioactivity were put forward. gradually it was realized that the radiation produced by radioactive decay was ionizing radiation, and that even quantities too small to burn could pose a severe long - term hazard. many of the scientists working on radioactivity died of cancer as a result of their exposure. radioactive patent medicines mostly disappeared, but other applications of radioactive materials persisted, such as the use of radium salts to produce glowing dials on meters. as the atom came to be better understood, the nature of radioactivity became clearer. some larger atomic nuclei are unstable, and so decay ( release matter or energy ) after a random interval. the three forms of radiation that becquerel and the curies discovered are also more fully understood. alpha decay is when a nucleus releases an alpha particle, which is two protons and two neutrons, equivalent to a helium nucleus. beta decay is the release of a beta particle, a high - energy electron. gamma decay releases gamma rays, which unlike alpha and beta radiation are not matter but electromagnetic radiation of very high frequency, and therefore energy. this type of radiation is the most dangerous and most difficult to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self the decay rate for isotopes subject to extreme pressures, those differences were too small to significantly impact date estimates. the constancy of the decay rates is also governed by first principles in quantum mechanics, wherein any deviation in the rate would require a change in the fundamental constants. according to these principles, a change in the fundamental constants could not influence different elements uniformly, and a comparison between each of the elements ' resulting unique chronological timescales would then give inconsistent time estimates. in refutation of young earth claims of inconstant decay rates affecting the reliability of radiometric dating, roger c. wiens, a physicist specializing in isotope dating states : there are only three quite technical instances where a half - life changes, and these do not affect the dating methods : " only one technical exception occurs under terrestrial conditions, and this is not for an isotope used for dating.... the artificially - produced isotope, beryllium - 7 has been shown to change by up to 1. 5 %, depending on its chemical environment.... heavier atoms are even less subject to these minute changes, so the dates of rocks made by electron - capture decays would only be off by at most a few hundredths of a percent. " "... another case is material inside of stars, which is in a plasma state where electrons are not bound to atoms. in the extremely hot stellar environment, a completely different kind of decay can occur. ' bound - state beta decay ' occurs when the nucleus emits an electron into a bound electronic state close to the nucleus.... all normal matter, such as everything on earth, the moon, meteorites, etc. has electrons in normal positions, so these instances never apply to rocks, or anything colder than several hundred thousand degrees. " " the last case also involves very fast - moving matter. it has been demonstrated by atomic clocks in very fast spacecraft. these atomic clocks slow down very slightly ( only a second or so per year ) as predicted by einstein ' s theory of relativity. no rocks in our solar system are going fast enough to make a noticeable change in their dates. " = = = = radiohaloes = = = = in the 1970s, young earth creationist robert v. gentry proposed that radiohaloes in certain granites represented evidence for the earth being created instantaneously rather than gradually. this idea has been criticized by physicists and geologists on many grounds including that the rocks gentry studied were not primordial and that the radionucl radiation exposure. marie curie died from aplastic anemia which resulted from her high levels of exposure. two scientists, an american and canadian respectively, harry daghlian and louis slotin, died after mishandling the same plutonium mass. unlike conventional weapons, the intense light, heat, and explosive force is not the only deadly component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. civilian nuclear and radiological accidents primarily involve nuclear power plants. most common are nuclear leaks that expose workers to hazardous material. a nuclear meltdown refers to the more serious hazard of releasing nuclear material into the surrounding environment. the most significant meltdowns occurred at three mile island in pennsylvania and chernobyl in the soviet ukraine. the earthquake and tsunami on march 11, 2011 caused serious damage to three nuclear reactors and a spent fuel storage pond at the fukushima daiichi nuclear power plant in japan. military reactors that experienced similar accidents were windscale in the united kingdom and sl - 1 in the united states. military accidents usually involve the loss or unexpected detonation of nuclear weapons. the castle bravo test in 1954 produced a larger yield than expected, which contaminated nearby islands, a japanese fishing boat ( with one fatality ), and raised concerns about contaminated fish in japan. in the 1950s through 1970s, several nuclear bombs were lost from submarines and aircraft, some of which have never been recovered. the last twenty years have seen a marked decline in such accidents. = = examples of environmental benefits = = proponents of nuclear energy note that annually, nuclear - generated electricity reduces 470 million metric tons of carbon dioxide emissions that would otherwise come from fossil fuels. additionally, the amount of comparatively low waste that nuclear energy does create is safely disposed of by the large scale nuclear energy production facilities or it is repurposed / recycled for other energy uses. proponents of nuclear energy also bring to attention the opportunity cost of utilizing other forms of electricity. for example, the environmental protection agency estimates that coal kills 30, 000 people a year, as a result of its environmental impact, while 60 people died in the chernobyl disaster. a real world example of impact provided by proponents of nuclear energy is the 650, 000 ton increase in carbon emissions in the two months following the closure of the vermont yankee nuclear plant. = = see also = = atomic age lists of nuclear disasters and radioactive incidents nuclear power debate outline of nuclear technology radiology = = references = = = = external links = = nuclear energy institute – beneficial uses it is well known and well established by scientific observation that a free neutron radioactively decays into a proton plus an electron plus an anti - neutrino with a mean life time before decay of about 900 seconds. that established fact conflicts sharply with the hypothesis that the neutron is composed of two down plus one up quark and that the proton is composed of one down plus two up quarks. that conflict throws doubt on the entire quark hypothesis. did. a uranium bomb, little boy, was dropped on the japanese city hiroshima on august 6, 1945, followed three days later by the plutonium - based fat man on nagasaki. in the wake of unprecedented devastation and casualties from a single weapon, the japanese government soon surrendered, ending world war ii. since these bombings, no nuclear weapons have been deployed offensively. nevertheless, they prompted an arms race to develop increasingly destructive bombs to provide a nuclear deterrent. just over four years later, on august 29, 1949, the soviet union detonated its first fission weapon. the united kingdom followed on october 2, 1952 ; france, on february 13, 1960 ; and china component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. a radiological weapon is a type of nuclear weapon designed to distribute hazardous nuclear material in enemy areas. such a weapon would not have the explosive capability of a fission or fusion bomb, but would kill many people and contaminate a large area. a radiological weapon has never been deployed. while considered useless by a conventional military, such a weapon raises concerns over nuclear terrorism. there have been over 2, 000 nuclear tests conducted since 1945. in 1963, all nuclear and many non - nuclear states signed the limited test ban treaty, pledging to refrain from testing nuclear weapons in the atmosphere, underwater, or in outer space. the treaty permitted underground nuclear testing. france continued atmospheric testing until 1974, while china continued up until 1980. the last underground test by the united states was in 1992, the soviet union in 1990, the united kingdom in 1991, and both france and china continued testing until 1996. after signing the comprehensive test ban treaty in 1996 ( which had as of 2011 not entered into force ), all of these states have pledged to discontinue all nuclear testing. non - signatories india and pakistan last tested nuclear weapons in 1998. nuclear weapons are the most destructive weapons known - the archetypal weapons of mass destruction. throughout the cold war, the opposing powers had huge nuclear arsenals, sufficient to kill hundreds of millions of people. generations of people grew up under the shadow of nuclear devastation, portrayed in films such as dr. strangelove and the atomic cafe. however, the tremendous energy release in the detonation of a nuclear weapon also suggested the possibility of a new energy source. = = civilian uses = = = = = nuclear power = = = nuclear power is a type of nuclear technology involving the controlled use of nuclear fission . nuclear weapons are considered weapons of mass destruction, and their use and control has been a major aspect of international policy since their debut. the design of a nuclear weapon is more complicated than it might seem. such a weapon must hold one or more subcritical fissile masses stable for deployment, then induce criticality ( create a critical mass ) for detonation. it also is quite difficult to ensure that such a chain reaction consumes a significant fraction of the fuel before the device flies apart. the procurement of a nuclear fuel is also more difficult than it might seem, since sufficiently unstable substances for this process do not currently occur naturally on earth in suitable amounts. one isotope of uranium, namely uranium - 235, is naturally occurring and sufficiently unstable, but it is always found mixed with the more stable isotope uranium - 238. the latter accounts for more than 99 % of the weight of natural uranium. therefore, some method of isotope separation based on the weight of three neutrons must be performed to enrich ( isolate ) uranium - 235. alternatively, the element plutonium possesses an isotope that is sufficiently unstable for this process to be usable. terrestrial plutonium does not currently occur naturally in sufficient quantities for such use, so it must be manufactured in a nuclear reactor. ultimately, the manhattan project manufactured nuclear weapons based on each of these elements. they detonated the first nuclear weapon in a test code - named " trinity ", near alamogordo, new mexico, on july 16, 1945. the test was conducted to ensure that the implosion method of detonation would work, which it did. a uranium bomb, little boy, was dropped on the japanese city hiroshima on august 6, 1945, followed three days later by the plutonium - based fat man on nagasaki. in the wake of unprecedented devastation and casualties from a single weapon, the japanese government soon surrendered, ending world war ii. since these bombings, no nuclear weapons have been deployed offensively. nevertheless, they prompted an arms race to develop increasingly destructive bombs to provide a nuclear deterrent. just over four years later, on august 29, 1949, the soviet union detonated its first fission weapon. the united kingdom followed on october 2, 1952 ; france, on february 13, 1960 ; and china component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. a radiological weapon is a type of nuclear weapon designed to distribute hazardous nuclear material in enemy areas. such a weapon would not have the explosive capability of a fission or Question: What type of isotopes have short half-lives and are given in very low doses? A) radionuclides B) stable isotopes C) radioisotopes D) gasses	C) radioisotopes
Context: it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ft of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = meiosis is a central feature of sexual reproduction in eukaryotes, and the most fundamental function of meiosis appears to be conservation of the integrity of the genome that is passed on to progeny by parents. two aspects of sexual reproduction, meiotic recombination and outcrossing, are likely maintained respectively by the adaptive advantages of recombinational repair of genomic dna damage and genetic complementation which masks the expression of deleterious recessive mutations. the beneficial effect of genetic complementation, derived from outcrossing ( cross - fertilization ) is also referred to as hybrid vigor or heterosis. charles protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = mei ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = meiosis is a central feature of sexual reproduction in eukaryotes, and the most fundamental function of meiosis appears to be conservation of the integrity of the genome that is passed on to progeny by parents. two aspects of sexual reproduction, meiotic recombination and outcrossing, are likely maintained respectively by the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = meiosis is a central feature of sexual reproduction in eukaryotes, and the most fundamental function of meiosis appears to be conservation of the integrity of the genome that is passed on to progeny by parents. two aspects of sexual reproduction, meiotic recombination and outcrossing, are likely maintained respectively by the adaptive advantages of recombinational repair of genomic dna damage and genetic complementation which masks the expression of deleterious recessive mutations. the beneficial effect of genetic complementation, derived from outcrossing ( cross - fertilization ) is also referred to as hybrid vigor or heterosis. charles darwin in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted “ the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilis activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing , depending on the type of receptor. for instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. other types of receptors include protein kinase receptors ( e. g., receptor for the hormone insulin ) and g protein - coupled receptors. activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, . most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell, there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support Question: What is the multi-phase process in which the nucleus of a eukaryotic cell divides? A) Osmosis B) mitosis C) cytokinesis D) fission	B) mitosis
Context: classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filtration behavior and selectivity. the selectivity is highly dependent on the separation process, the composition of the membrane and its electrochemical properties in addition to the pore size. with high selectivity, isotopes can be enriched ( uranium enrichment ) in nuclear engineering or industrial gases like nitrogen can be recovered ( gas separation ). ideally, even racemics can be enriched with a suitable membrane. when choosing membranes selectivity has priority over a high permeability, as low flows can easily be offset by increasing the filter surface with a modular structure. in gas phase filtration different deposition mechanisms are operative, so that particles having sizes below the pore size of the membrane can be retained as well. = = membrane classification = = bio - membrane is classified in two categories, synthetic membrane and natural membrane. synthetic membranes further classified in organic and inorganic membranes. organic membrane sub classified polymeric membranes and inorganic membrane sub classified ceramic polymers. = = synthesis of biomass membrane cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with support matrices for tissue engineering applications. an adequate environment for promoting cell growth, differentiation, and integration with the existing tissue is a critical factor for cell - based building blocks. manipulation of any of these cell processes create alternative avenues for the development of new tissue ( e. g., cell reprogramming - somatic cells, vascularization ). = = = isolation = = = techniques for cell isolation depend on the cell source. centrifugation and apheresis are techniques used for extracting cells from biofluids ( e. g., blood ). whereas digestion processes, typically using enzymes to remove the extra ##ization. the fouling is usually induced faster at higher driving forces. membrane fouling and particle retention in a feed solution also builds up a concentration gradients and particle backflow ( concentration polarization ). the tangential flow devices are more cost and labor - intensive, but they are less susceptible to fouling due to the sweeping effects and high shear rates of the passing flow. the most commonly used synthetic membrane devices ( modules ) are flat sheets / plates, spiral wounds, and hollow fibers. flat membranes used in filtration and separation processes can be enhanced with surface patterning, where microscopic structures are introduced to improve performance. these patterns increase surface area, optimize water flow, and reduce fouling, leading to higher permeability and longer membrane lifespan. research has shown that such modifications can significantly enhance efficiency in water purification, energy applications, and industrial separations. flat plates are usually constructed as circular thin flat membrane surfaces to be used in dead - end geometry modules. spiral wounds are constructed from similar flat membranes but in the form of a " pocket " containing two membrane sheets separated by a highly porous support plate. several such pockets are then wound around a tube to create a tangential flow geometry and to reduce membrane fouling. hollow fiber modules consist of an assembly of self - supporting fibers with dense skin separation layers, and a more open matrix helping to withstand pressure gradients and maintain structural integrity. the hollow fiber modules can contain up to 10, 000 fibers ranging from 200 to 2500 μm in diameter ; the main advantage of hollow fiber modules is the very large surface area within an enclosed volume, increasing the efficiency of the separation process. the disc tube module uses a cross - flow geometry and consists of a pressure tube and hydraulic discs, which are held by a central tension rod, and membrane cushions that lie between two discs. = = membrane performance and governing equations = = the selection of synthetic membranes for a targeted separation process is usually based on few requirements. membranes have to provide enough mass transfer area to process large amounts of feed stream. the selected membrane has to have high selectivity ( rejection ) properties for certain particles ; it has to resist fouling and to have high mechanical stability. it also needs to be reproducible and to have low manufacturing costs. the main modeling equation for the dead - end filtration at constant pressure drop is represented by darcy ' s law : d v p d t = q = δ p μ a ( 1 r m + r ) { \ displaystyle { \ frac { dv _ the magnetization of superconducting samples is influenced by their porosity. in addition to structural modifications and improved cooling, the presence of pores also plays a role in trapping magnetic flux. pores have an impact on the irreversibility field, the full penetration field, and the remnant magnetization. generally, as porosity increases, these parameters tend to decrease. however, in the case of mesoscopic samples or samples with low critical current densities, increased porosity can actually enhance the trapping of magnetic flux. this scaffold and cells were placed in a bioreactor, where it matured to become a partially or fully transplantable organ. the work was called a " landmark ". the lab first stripped the cells away from a rat heart ( a process called " decellularization " ) and then injected rat stem cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with support matrices for tissue engineering applications. an adequate environment for promoting cell growth, differentiation, and integration with the existing tissue is a critical factor for cell - based building blocks. manipulation of any of these cell processes create alternative avenues for the development of new tissue ( e. g., cell reprogramming - somatic blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of the manufacturer. one common distinction is by nominal pore size. it describes the maximum pore size distribution and gives only vague information about the retention capacity of a membrane. the exclusion limit or " cut - off " of the membrane is usually specified in the form of nmwc ( nominal molecular weight cut - off, or mwco, molecular weight cut off, with units in dalton ). it is defined as the minimum molecular weight of a globular molecule that is retained to 90 % by the membrane. the cut - off, depending on the method, can by converted to so - called d90, which is then expressed in a metric unit. in practice the mwco of the membrane should be at least 20 % lower than the molecular weight of the molecule that is to be separated. using track etched mica membranes beck and schultz demonstrated that hindered diffusion of molecules in pores can be described by the rankin equation. filter membranes are divided into four classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filt the thickness of freshly made soap films is usually in the micron range, and interference colors make thickness fluctuations easily visible. circular patterns of constant thickness are commonly observed, either a thin film disc in a thicker film or the reverse. in this letter, we evidence the line tension at the origin of these circular patterns. using a well controlled soap film preparation, we produce a piece of thin film surrounded by a thicker film. the thickness profile, measured with a spectral camera, leads to a line tension of the order of 0. 1 nn which drives the relaxation of the thin film shape, initially very elongated, toward a circular shape. a balance between line tension and air friction leads to a quantitative prediction of the relaxation process. such a line tension is expected to play a role in the production of marginal regeneration patches, involved in soap film drainage and stability. ##ilage generated without the use of exogenous scaffold material. in this methodology, all material in the construct is cellular produced directly by the cells. bioartificial heart : doris taylor ' s lab constructed a biocompatible rat heart by re - cellularising a de - cellularised rat heart. this scaffold and cells were placed in a bioreactor, where it matured to become a partially or fully transplantable organ. the work was called a " landmark ". the lab first stripped the cells away from a rat heart ( a process called " decellularization " ) and then injected rat stem cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with metric unit. in practice the mwco of the membrane should be at least 20 % lower than the molecular weight of the molecule that is to be separated. using track etched mica membranes beck and schultz demonstrated that hindered diffusion of molecules in pores can be described by the rankin equation. filter membranes are divided into four classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filtration behavior and selectivity. the selectivity is highly dependent on the separation process, the composition of the membrane and its electrochemical properties in addition to the pore size. with high selectivity, isotopes can be enriched ( uranium enrichment ) in nuclear engineering or industrial gases like nitrogen can be recovered ( gas separation ). ideally, even racemics can be enriched with a suitable membrane. when choosing membranes selectivity has priority over a high permeability, as low flows can easily be offset by increasing the filter surface with a modular structure. in gas phase filtration different deposition mechanisms are operative, so that particles having sizes below the Question: What are microscopic vessels with very thin, porous walls? A) capillaries B) arteries C) veins D) valves	A) capillaries
Context: unitary recordings in freely - moving pulse weakly electric fish suggest spike timing encoding of electrosensory signals to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthala onset of electro - chemical corrosion. similar problems are encountered in coastal and offshore structures. = = = anti - fouling = = = anti - fouling is the process of eliminating obstructive organisms from essential components of seawater systems. depending on the nature and location of marine growth, this process is performed in a number of different ways : marine organisms may grow and attach to the surfaces of the outboard suction inlets used to obtain water for cooling systems. electro - chlorination involves running high electrical current through sea water, altering the water ' s chemical composition to create sodium hypochlorite, purging any bio - matter. an electrolytic method of anti - fouling involves running electrical current through two anodes ( scardino, 2009 ). these anodes typically consist of copper and aluminum ( or alternatively, iron ). the first metal, copper anode, releases its ion into the water, creating an environment that is too toxic for bio - matter. the second metal, aluminum, coats the inside of the pipes to prevent corrosion. other forms of marine growth such as mussels and algae may attach themselves to the bottom of a ship ' s hull. this growth interferes with the smoothness and uniformity of the ship ' s hull, causing the ship to have a less hydrodynamic shape that causes it to be slower and less fuel - efficient. marine growth on the hull can be remedied by using special paint that prevents the growth of such organisms. = = = pollution control = = = = = = = sulfur emission = = = = the burning of marine fuels releases harmful pollutants into the atmosphere. ships burn marine diesel in addition to heavy fuel oil. heavy fuel oil, being the heaviest of refined oils, releases sulfur dioxide when burned. sulfur dioxide emissions have the potential to raise atmospheric and ocean acidity causing harm to marine life. however, heavy fuel oil may only be burned in international waters due to the pollution created. it is commercially advantageous due to the cost effectiveness compared to other marine fuels. it is prospected that heavy fuel oil will be phased out of commercial use by the year 2020 ( smith, 2018 ). = = = = oil and water discharge = = = = water, oil, and other substances collect at the bottom of the ship in what is known as the bilge. bilge water is pumped overboard, but must pass a pollution threshold test of 15 ppm ( parts per million ) of oil to be discharged. water is tested , characterizing organs as predominantly yin or yang, and understood the relationship between the pulse, the heart, and the flow of blood in the body centuries before it became accepted in the west. little evidence survives of how ancient indian cultures around the indus river understood nature, but some of their perspectives may be reflected in the vedas, a set of sacred hindu texts. they reveal a conception of the universe as ever - expanding and constantly being recycled and reformed. surgeons in the ayurvedic tradition saw health and illness as a combination of three humors : wind, bile and phlegm. a healthy life resulted from a balance among these humors. in ayurvedic thought, the body consisted of five elements : earth, water, fire, wind, and space. ayurvedic surgeons performed complex surgeries and developed a detailed understanding of human anatomy. pre - socratic philosophers in ancient greek culture brought natural philosophy a step closer to direct inquiry about cause and effect in nature between 600 and 400 bc. however, an element of magic and mythology remained. natural phenomena such as earthquakes and eclipses were explained increasingly in the context of nature itself instead of being attributed to angry gods. thales of miletus, an early philosopher who lived from 625 to 546 bc, explained earthquakes by theorizing that the world floated on water and that water was the fundamental element in nature. in the 5th century bc, leucippus was an early exponent of atomism, the idea that the world is made up of fundamental indivisible particles. pythagoras applied greek innovations in mathematics to astronomy and suggested that the earth was spherical. = = = aristotelian natural philosophy ( 400 bc – 1100 ad ) = = = later socratic and platonic thought focused on ethics, morals, and art and did not attempt an investigation of the physical world ; plato criticized pre - socratic thinkers as materialists and anti - religionists. aristotle, however, a student of plato who lived from 384 to 322 bc, paid closer attention to the natural world in his philosophy. in his history of animals, he described the inner workings of 110 species, including the stingray, catfish and bee. he investigated chick embryos by breaking open eggs and observing them at various stages of development. aristotle ' s works were influential through the 16th century, and he is considered to be the father of biology for his pioneering work in that science. he also presented philosophies about physics, nature, and astronomy using nintendo ' s super smash bros. melee fighting game can be emulated on modern hardware allowing us to inspect internal memory states, such as character positions. we created an ai that avoids being hit by training using these internal memory states and outputting controller button presses. after training on a month ' s worth of melee matches, our best agent learned to avoid the toughest ai built into the game for a full minute 74. 6 % of the time. required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the results of an experiment are presented whose aim is to explore the relationship between respiration and cerebral oxygenation. measurements of end tidal co2 ( etco2 ) were taken simultaneously with cerebral oxygen saturation ( rso2 ) using the invos cerebral oximeter of somanetics. due to the device limitations we could explore only subjects who could perform with a breathing rate of around 2 / min or less. six subjects were used who were experienced in yoga breathing techniques. they performed an identical periodic breathing exercise including periodicity of about 2 / min. the results of all six subjects clearly show a periodic change of cerebral oxygenation with the same period as the breathing exercises. similar periodic changes in blood volume index were observed as well. cortisol, corticosterone and aldosterone activate full - length glucocorticoid receptor ( gr ) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. activation by aldosterone a mineralocorticoid, indicates partial divergence of elephant shark gr from the mr. progesterone activates elephant shark mr, but not elephant shark gr. progesterone inhibits steroid binding to elephant shark gr, but not to human gr. deletion of the n - terminal domain ( ntd ) from elephant shark gr ( truncated gr ) reduced the response to corticosteroids, while truncated and full - length elephant shark mr had similar responses to corticosteroids. chimeras of elephant shark gr ntd fused to mr dbd + lbd had increased activation by corticosteroids and progesterone compared to full - length elephant shark mr. elephant shark mr ntd fused to gr dbd + lbd had similar activation as full - length elephant shark mr, indicating that activation of human gr by the ntd evolved early in gr divergence from the mr. blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of zero - field muon spin rotation experiments provide evidence for an antiferromagnetic component in the magnetic structure of the intermetallics zrzn2. Question: Which part of a fish helps them breathe? A) pores B) gills C) layers D) fins	B) gills
Context: their mechanical properties. = = tissue culture = = in many cases, creation of functional tissues and biological structures in vitro requires extensive culturing to promote survival, growth and inducement of functionality. in general, the basic requirements of cells must be maintained in culture, which include oxygen, ph, humidity, temperature, nutrients and osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can cell. in juxtacrine signaling, there is direct contact between the signaling and responding cells. finally, hormones are ligands that travel through the circulatory systems of animals or vascular systems of plants to reach their target cells. once a ligand binds with a receptor, it can influence the behavior of another cell, depending on the type of receptor. for instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. other types of receptors include protein kinase receptors ( e. g., receptor for the hormone insulin ) and g protein - coupled receptors. activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions the reply to g. w. bruhn is added. include the manufacturing of drugs, creation of model animals that mimic human conditions and gene therapy. one of the earliest uses of genetic engineering was to mass - produce human insulin in bacteria. this application has now been applied to human growth hormones, follicle stimulating hormones ( for treating infertility ), human albumin, monoclonal antibodies, antihemophilic factors, vaccines and many other drugs. mouse hybridomas, cells fused together to create monoclonal antibodies, have been adapted through genetic engineering to create human monoclonal antibodies. genetically engineered viruses are being developed that can still confer immunity, but lack the infectious sequences. genetic engineering is also used to create animal models of human diseases. genetically modified mice are the most common genetically engineered animal model. they have been used to study and model cancer ( the oncomouse ), obesity, heart disease, diabetes, arthritis, substance abuse, anxiety, aging and parkinson disease. potential cures can be tested against these mouse models. gene therapy is the genetic engineering of humans, generally by replacing defective genes with effective ones. clinical research using somatic gene therapy has been conducted with several diseases, including x - linked scid, chronic lymphocytic leukemia ( cll ), and parkinson ' s disease. in 2012, alipogene tiparvovec became the first gene therapy treatment to be approved for clinical use. in 2015 a virus was used to insert a healthy gene into the skin cells of a boy suffering from a rare skin disease, epidermolysis bullosa, in order to grow, and then graft healthy skin onto 80 percent of the boy ' s body which was affected by the illness. germline gene therapy would result in any change being inheritable, which has raised concerns within the scientific community. in 2015, crispr was used to edit the dna of non - viable human embryos, leading scientists of major world academies to call for a moratorium on inheritable human genome edits. there are also concerns that the technology could be used not just for treatment, but for enhancement, modification or alteration of a human beings ' appearance, adaptability, intelligence, character or behavior. the distinction between cure and enhancement can also be difficult to establish. in november 2018, he jiankui announced that he had edited the genomes of two human embryos, to attempt to disable the ccr5 gene, which codes for a receptor that hiv uses to enter cells. the work was widely condemned as unethical, dangerous, protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the ability of cells to receive, process, and transmit signals with its environment and with itself. signals can be non - chemical such as light, electrical impulses, and heat, or chemical signals ( or ligands ) that interact with receptors, which can be found embedded in the cell membrane of another cell or located deep inside a cell. there are generally four types of chemical signals : autocrine, paracrine, juxtacrine, and hormones. in autocrine signaling, the ligand affects the same cell that releases it. tumor cells, for example, can reproduce uncontrollably because they release signals that initiate their own self - division. in paracrine signaling, the ligand diffuses to nearby cells and affects them. for example, brain cells called neurons release ligands called neurotransmitters that diffuse across a synaptic cleft to bind with a receptor on an adjacent cell such as another neuron or muscle cell. in juxtacrine signaling, there is direct contact between the signaling and responding cells. finally, hormones are ligands that travel through the circulatory systems of animals or vascular systems of plants to reach their target cells. once a ligand binds with a receptor, it can influence the behavior of another cell, depending on the type of receptor. for instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. other types of receptors include protein kinase receptors ( e. g., receptor for the hormone insulin ) and g protein - coupled receptors. activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause this article present a new, direct and simple formula for constructing mignotte sequences. life, but most current gm crops are modified to increase resistance to insects and herbicides. glofish, the first gmo designed as a pet, was sold in the united states in december 2003. in 2016 salmon modified with a growth hormone were sold. genetic engineering has been applied in numerous fields including research, medicine, industrial biotechnology and agriculture. in research, gmos are used to study gene function and expression through loss of function, gain of function, tracking and expression experiments. by knocking out genes responsible for certain conditions it is possible to create animal model organisms of human diseases. as well as producing hormones, vaccines and other drugs, genetic engineering has the potential to cure genetic diseases through gene therapy. chinese hamster ovary ( cho ) cells are used in industrial genetic engineering. additionally mrna vaccines are made through genetic engineering to prevent infections by viruses such as covid - 19. the same techniques that are used to produce drugs can also have industrial applications such as producing enzymes for laundry detergent, cheeses and other products. the rise of commercialised genetically modified crops has provided economic benefit to farmers in many different countries, but has also been the source of most of the controversy surrounding the technology. this has been present since its early use ; the first field trials were destroyed by anti - gm activists. although there is a scientific consensus that currently available food derived from gm crops poses no greater risk to human health than conventional food, critics consider gm food safety a leading concern. gene flow, impact on non - target organisms, control of the food supply and intellectual property rights have also been raised as potential issues. these concerns have led to the development of a regulatory framework, which started in 1975. it has led to an international treaty, the cartagena protocol on biosafety, that was adopted in 2000. individual countries have developed their own regulatory systems regarding gmos, with the most marked differences occurring between the united states and europe. = = overview = = genetic engineering is a process that alters the genetic structure of an organism by either removing or introducing dna, or modifying existing genetic material in situ. unlike traditional animal and plant breeding, which involves doing multiple crosses and then selecting for the organism with the desired phenotype, genetic engineering takes the gene directly from one organism and delivers it to the other. this is much faster, can be used to insert any genes from any organism ( even ones from different domains ) and prevents other undesirable genes from also being added. genetic engineering could potentially fix severe genetic disorders in humans by replacing the from the oil of jasminum grandiflorum which regulates wound responses in plants by unblocking the expression of genes required in the systemic acquired resistance response to pathogen attack. in addition to being the primary energy source for plants, light functions as a signalling device, providing information to the plant, such as how much sunlight the plant receives each day. this can result in adaptive changes in a process known as photomorphogenesis. phytochromes are the photoreceptors in a plant that are sensitive to light. = = plant anatomy and morphology = = plant anatomy is the study of the structure of plant cells and tissues, whereas plant morphology is the study of their external form. all plants are multicellular eukaryotes, their dna stored in nuclei. the characteristic features of plant cells that distinguish them from those of animals and fungi include a primary cell wall composed of the polysaccharides cellulose, hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthala activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a Question: What produces hormones referred to as thymosins, which contribute to the development of the immune response in infants? A) heart B) pancreas C) receptors D) thymus	D) thymus
Context: becomes quite gentle. accordingly, in large basins, rivers in most cases begin as torrents with a variable flow, and end as gently flowing rivers with a comparatively regular discharge. the irregular flow of rivers throughout their course forms one of the main difficulties in devising works for mitigating inundations or for increasing the navigable capabilities of rivers. in tropical countries subject to periodical rains, the rivers are in flood during the rainy season and have hardly any flow during the rest of the year, while in temperate regions, where the rainfall is more evenly distributed throughout the year, evaporation causes the available rainfall to be much less in hot summer weather than in the winter months, so that the rivers fall to their low stage in the summer and are liable to be in flood in the winter. in fact, with a temperate climate, the year may be divided into a warm and a cold season, extending from may to october and from november to april in the northern hemisphere respectively ; the rivers are low and moderate floods are of rare occurrence during the warm period, and the rivers are high and subject to occasional heavy floods after a considerable rainfall during the cold period in most years. the only exceptions are rivers which have their sources amongst mountains clad with perpetual snow and are fed by glaciers ; their floods occur in the summer from the melting of snow and ice, as exemplified by the rhone above the lake of geneva, and the arve which joins it below. but even these rivers are liable to have their flow modified by the influx of tributaries subject to different conditions, so that the rhone below lyon has a more uniform discharge than most rivers, as the summer floods of the arve are counteracted to a great extent by the low stage of the saone flowing into the rhone at lyon, which has its floods in the winter when the arve, on the contrary, is low. another serious obstacle encountered in river engineering consists in the large quantity of detritus they bring down in flood - time, derived mainly from the disintegration of the surface layers of the hills and slopes in the upper parts of the valleys by glaciers, frost and rain. the power of a current to transport materials varies with its velocity, so that torrents with a rapid fall near the sources of rivers can carry down rocks, boulders and large stones, which are by degrees ground by attrition in their onward course into slate, gravel, sand and silt, simultaneously with the gradual reduction in fall, and, consequently, in the transporting force of the current. accordingly, under covid - 19, also known as novel coronavirus disease, is a highly contagious disease that first surfaced in china in late 2019. sars - cov - 2 is a coronavirus that belongs to the vast family of coronaviruses that causes this disease. the sickness originally appeared in wuhan, china in december 2019 and quickly spread to over 213 nations, becoming a global pandemic. fever, dry cough, and tiredness are the most typical covid - 19 symptoms. aches, pains, and difficulty breathing are some of the other symptoms that patients may face. the majority of these symptoms are indicators of respiratory infections and lung abnormalities, which radiologists can identify. chest x - rays of covid - 19 patients seem similar, with patchy and hazy lungs rather than clear and healthy lungs. on x - rays, however, pneumonia and other chronic lung disorders can resemble covid - 19. trained radiologists must be able to distinguish between covid - 19 and an illness that is less contagious. our ai algorithm seeks to give doctors a quantitative estimate of the risk of deterioration. so that patients at high risk of deterioration can be triaged and treated efficiently. the method could be particularly useful in pandemic hotspots when screening upon admission is important for allocating limited resources like hospital beds. navigable capabilities of rivers. in tropical countries subject to periodical rains, the rivers are in flood during the rainy season and have hardly any flow during the rest of the year, while in temperate regions, where the rainfall is more evenly distributed throughout the year, evaporation causes the available rainfall to be much less in hot summer weather than in the winter months, so that the rivers fall to their low stage in the summer and are liable to be in flood in the winter. in fact, with a temperate climate, the year may be divided into a warm and a cold season, extending from may to october and from november to april in the northern hemisphere respectively ; the rivers are low and moderate floods are of rare occurrence during the warm period, and the rivers are high and subject to occasional heavy floods after a considerable rainfall during the cold period in most years. the only exceptions are rivers which have their sources amongst mountains clad with perpetual snow and are fed by glaciers ; their floods occur in the summer from the melting of snow and ice, as exemplified by the rhone above the lake of geneva, and the arve which joins it below. but even these rivers are liable to have their flow modified by the influx of tributaries subject to different conditions, so that the rhone below lyon has a more uniform discharge than most rivers, as the summer floods of the arve are counteracted to a great extent by the low stage of the saone flowing into the rhone at lyon, which has its floods in the winter when the arve, on the contrary, is low. another serious obstacle encountered in river engineering consists in the large quantity of detritus they bring down in flood - time, derived mainly from the disintegration of the surface layers of the hills and slopes in the upper parts of the valleys by glaciers, frost and rain. the power of a current to transport materials varies with its velocity, so that torrents with a rapid fall near the sources of rivers can carry down rocks, boulders and large stones, which are by degrees ground by attrition in their onward course into slate, gravel, sand and silt, simultaneously with the gradual reduction in fall, and, consequently, in the transporting force of the current. accordingly, under ordinary conditions, most of the materials brought down from the high lands by torrential water courses are carried forward by the main river to the sea, or partially strewn over flat alluvial plains during floods ; the size of the materials forming the bed of the river or borne along by the stream is gradually reduced on proceeding sea when fast radio burst ( frb ) waves propagate through the local ( < 1 pc ) environment of the frb source, electrons in the plasma undergo large - amplitude oscillations. the finite - amplitude effects cause the effective plasma frequency and cyclotron frequency to be dependent on the wave strength. the dispersion measure and rotation measure should therefore vary slightly from burst to burst for a repeating source, depending on the luminosity and frequency of the individual burst. furthermore, free - free absorption of strong waves is suppressed due to the accelerated electrons ' reduced energy exchange in coulomb collisions. this allows bright low - frequency bursts to propagate through an environment that would be optically thick to low - amplitude waves. given a large sample of bursts from a repeating source, it would be possible to use the deficit of low - frequency and low - luminosity bursts to infer the emission measure of the local intervening plasma and its distance from the source. information about the local environment will shed light on the nature of frb sources. the first observations of saturn ' s visible - wavelength aurora were made by the cassini camera. the aurora was observed between 2006 and 2013 in the northern and southern hemispheres. the color of the aurora changes from pink at a few hundred km above the horizon to purple at 1000 - 1500 km above the horizon. the spectrum observed in 9 filters spanning wavelengths from 250 nm to 1000 nm has a prominent h - alpha line and roughly agrees with laboratory simulated auroras. auroras in both hemispheres vary dramatically with longitude. auroras form bright arcs between 70 and 80 degree latitude north and between 65 and 80 degree latitude south, which sometimes spiral around the pole, and sometimes form double arcs. a large 10, 000 - km - scale longitudinal brightness structure persists for more than 100 hours. this structure rotates approximately together with saturn. on top of the large steady structure, the auroras brighten suddenly on the timescales of a few minutes. these brightenings repeat with a period of about 1 hour. smaller, 1000 - km - scale structures may move faster or lag behind saturn ' s rotation on timescales of tens of minutes. the persistence of nearly - corotating large bright longitudinal structure in the auroral oval seen in two movies spanning 8 and 11 rotations gives an estimate on the period of 10. 65 $ \ pm $ 0. 15 h for 2009 in the northern oval and 10. 8 $ \ pm $ 0. 1 h for 2012 in the southern oval. the 2009 north aurora period is close to the north branch of saturn kilometric radiation ( skr ) detected at that time. , lightning strikes, tornadoes, building fires, wildfires, and mass shootings disabling most of the system if not the entirety of it. geographic redundancy locations can be more than 621 miles ( 999 km ) continental, more than 62 miles apart and less than 93 miles ( 150 km ) apart, less than 62 miles apart, but not on the same campus, or different buildings that are more than 300 feet ( 91 m ) apart on the same campus. the following methods can reduce the risks of damage by a fire conflagration : large buildings at least 80 feet ( 24 m ) to 110 feet ( 34 m ) apart, but sometimes a minimum of 210 feet ( 64 m ) apart. : 9 high - rise buildings at least 82 feet ( 25 m ) apart : 12 open spaces clear of flammable vegetation within 200 feet ( 61 m ) on each side of objects different wings on the same building, in rooms that are separated by more than 300 feet ( 91 m ) different floors on the same wing of a building in rooms that are horizontally offset by a minimum of 70 feet ( 21 m ) with fire walls between the rooms that are on different floors two rooms separated by another room, leaving at least a 70 - foot gap between the two rooms there should be a minimum of two separated fire walls and on opposite sides of a corridor geographic redundancy is used by amazon web services ( aws ), google cloud platform ( gcp ), microsoft azure, netflix, dropbox, salesforce, linkedin, paypal, twitter, facebook, apple icloud, cisco meraki, and many others to provide geographic redundancy, high availability, fault tolerance and to ensure availability and reliability for their cloud services. as another example, to minimize risk of damage from severe windstorms or water damage, buildings can be located at least 2 miles ( 3. 2 km ) away from the shore, with an elevation of at least 5 feet ( 1. 5 m ) above sea level. for additional protection, they can be located at least 100 feet ( 30 m ) away from flood plain areas. = = functions of redundancy = = the two functions of redundancy are passive redundancy and active redundancy. both functions prevent performance decline from exceeding specification limits without human intervention using extra capacity. passive redundancy uses excess capacity to reduce the impact of component failures. one common form of passive redundancy is the extra strength of cabling and struts used in bridges. approximately corresponds to the slope of the country it traverses ; as rivers rise close to the highest part of their basins, generally in hilly regions, their fall is rapid near their source and gradually diminishes, with occasional irregularities, until, in traversing plains along the latter part of their course, their fall usually becomes quite gentle. accordingly, in large basins, rivers in most cases begin as torrents with a variable flow, and end as gently flowing rivers with a comparatively regular discharge. the irregular flow of rivers throughout their course forms one of the main difficulties in devising works for mitigating inundations or for increasing the navigable capabilities of rivers. in tropical countries subject to periodical rains, the rivers are in flood during the rainy season and have hardly any flow during the rest of the year, while in temperate regions, where the rainfall is more evenly distributed throughout the year, evaporation causes the available rainfall to be much less in hot summer weather than in the winter months, so that the rivers fall to their low stage in the summer and are liable to be in flood in the winter. in fact, with a temperate climate, the year may be divided into a warm and a cold season, extending from may to october and from november to april in the northern hemisphere respectively ; the rivers are low and moderate floods are of rare occurrence during the warm period, and the rivers are high and subject to occasional heavy floods after a considerable rainfall during the cold period in most years. the only exceptions are rivers which have their sources amongst mountains clad with perpetual snow and are fed by glaciers ; their floods occur in the summer from the melting of snow and ice, as exemplified by the rhone above the lake of geneva, and the arve which joins it below. but even these rivers are liable to have their flow modified by the influx of tributaries subject to different conditions, so that the rhone below lyon has a more uniform discharge than most rivers, as the summer floods of the arve are counteracted to a great extent by the low stage of the saone flowing into the rhone at lyon, which has its floods in the winter when the arve, on the contrary, is low. another serious obstacle encountered in river engineering consists in the large quantity of detritus they bring down in flood - time, derived mainly from the disintegration of the surface layers of the hills and slopes in the upper parts of the valleys by glaciers, frost and rain. the power of a current to transport materials varies with its velocity, so that torrents with generation of direct current in zigzag carbon nanotubes due to harmonic mixing of two coherent electromagnetic waves is being considered. the electromagnetic waves have commensurate frequencies of omega and two omega. the rectification of the waves at high frequencies is quite smooth whiles at low frequencies there are some fluctuations. the nonohmicity observed in the i - vcharacteristics is attributed to the nonparabolicity of the electron energy band which is very strong in carbon nanotubes because of high stark component. it is observed that the current falls off faster at lower electric field than the case in superlattice. for omega tau equal to two? the external electric field strength emax for the observation of negative differential conductivity occurs around 1. 03x10e6 v / m which is quite weak. it is interesting to note that the peak of the curve shifts to the left with increasing value of omega tau? radar signal transmit a return microwave signal. this causes the aircraft to show up more strongly on the radar screen. the radar which triggers the transponder and receives the return beam, usually mounted on top of the primary radar dish, is called the secondary surveillance radar. since radar cannot measure an aircraft ' s altitude with any accuracy, the transponder also transmits back the aircraft ' s altitude measured by its altimeter, and an id number identifying the aircraft, which is displayed on the radar screen. electronic countermeasures ( ecm ) – military defensive electronic systems designed to degrade enemy radar effectiveness, or deceive it with false information, to prevent enemies from locating local forces. it often consists of powerful microwave transmitters that can mimic enemy radar signals to create false target indications on the enemy radar screens. marine radar – an s or x band radar on ships used to detect nearby ships and obstructions like bridges. a rotating antenna sweeps a vertical fan - shaped beam of microwaves around the water surface surrounding the craft out to the horizon. weather radar – a doppler radar which maps weather precipitation intensities and wind speeds with the echoes returned from raindrops and their radial velocity by their doppler shift. phased - array radar – a radar set that uses a phased array, a computer - controlled antenna that can steer the radar beam quickly to point in different directions without moving the antenna. phased - array radars were developed by the military to track fast - moving missiles and aircraft. they are widely used in military equipment and are now spreading to civilian applications. synthetic aperture radar ( sar ) – a specialized airborne radar set that produces a high - resolution map of ground terrain. the radar is mounted on an aircraft or spacecraft and the radar antenna radiates a beam of radio waves sideways at right angles to the direction of motion, toward the ground. in processing the return radar signal, the motion of the vehicle is used to simulate a large antenna, giving the radar a higher resolution. ground - penetrating radar – a specialized radar instrument that is rolled along the ground surface in a cart and transmits a beam of radio waves into the ground, producing an image of subsurface objects. frequencies from 100 mhz to a few ghz are used. since radio waves cannot penetrate very far into earth, the depth of gpr is limited to about 50 feet. collision avoidance system – a short range radar or lidar system on an automobile or vehicle that detects if the vehicle is about to collide with an object and applies the brakes to , airline baggage tags and are implanted under the skin in pets and livestock ( microchip implant ) and even people. privacy concerns have been addressed with tags that use encrypted signals and authenticate the reader before responding. passive tags use 125 – 134 khz, 13, 900 mhz and 2. 4 and 5 ghz ism bands and have a short range. active tags, powered by a battery, are larger but can transmit a stronger signal, giving them a range of hundreds of meters. submarine communication – when submerged, submarines are cut off from all ordinary radio communication with their military command authorities by the conductive seawater. however radio waves of low enough frequencies, in the vlf ( 30 to 3 khz ) and elf ( below 3 khz ) bands are able to penetrate seawater. navies operate large shore transmitting stations with power output in the megawatt range to transmit encrypted messages to their submarines in the world ' s oceans. due to the small bandwidth, these systems cannot transmit voice, only text messages at a slow data rate. the communication channel is one - way, since the long antennas needed to transmit vlf or elf waves cannot fit on a submarine. vlf transmitters use miles long wire antennas like umbrella antennas. a few nations use elf transmitters operating around 80 hz, which can communicate with submarines at lower depths. these use even larger antennas called ground dipoles, consisting of two ground ( earth ) connections 23 – 60 km ( 14 – 37 miles ) apart, linked by overhead transmission lines to a power plant transmitter. = = = space communication = = = this is radio communication between a spacecraft and an earth - based ground station, or another spacecraft. communication with spacecraft involves the longest transmission distances of any radio links, up to billions of kilometers for interplanetary spacecraft. in order to receive the weak signals from distant spacecraft, satellite ground stations use large parabolic " dish " antennas up to 25 metres ( 82 ft ) in diameter and extremely sensitive receivers. high frequencies in the microwave band are used, since microwaves pass through the ionosphere without refraction, and at microwave frequencies the high - gain antennas needed to focus the radio energy into a narrow beam pointed at the receiver are small and take up a minimum of space in a satellite. portions of the uhf, l, c, s, ku and ka band are allocated for space communication. a radio link that transmits data from the earth ' s surface to a spacecraft is called an uplink, while a link that transmits data from the spacecraft Question: Some of the biggest waves occur with what type of storm that forms over the ocean and brings high winds? A) tropical depression B) hurricane C) tsunami D) tropical storm	B) hurricane
Context: sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, , social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, christian emphasis on practical charity gave rise to the development of systematic nursing and hospitals, and the catholic church today remains the largest non - government provider of medical services in the world. advanced industrial countries ( with the exception of the united states ) and many developing countries provide medical services through a system of universal health care that aims to cortisol, corticosterone and aldosterone activate full - length glucocorticoid receptor ( gr ) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. activation by aldosterone a mineralocorticoid, indicates partial divergence of elephant shark gr from the mr. progesterone activates elephant shark mr, but not elephant shark gr. progesterone inhibits steroid binding to elephant shark gr, but not to human gr. deletion of the n - terminal domain ( ntd ) from elephant shark gr ( truncated gr ) reduced the response to corticosteroids, while truncated and full - length elephant shark mr had similar responses to corticosteroids. chimeras of elephant shark gr ntd fused to mr dbd + lbd had increased activation by corticosteroids and progesterone compared to full - length elephant shark mr. elephant shark mr ntd fused to gr dbd + lbd had similar activation as full - length elephant shark mr, indicating that activation of human gr by the ntd evolved early in gr divergence from the mr. behavioral responses to different stimuli, one can understand something about how those stimuli are processed. lewandowski & strohmetz ( 2009 ) reviewed a collection of innovative uses of behavioral measurement in psychology including behavioral traces, behavioral observations, and behavioral choice. behavioral traces are pieces of evidence that indicate behavior occurred, but the actor is not present ( e. g., litter in a parking lot or readings on an electric meter ). behavioral observations involve the direct witnessing of the actor engaging in the behavior ( e. g., watching how close a person sits next to another person ). behavioral choices are when a person selects between two or more options ( e. g., voting behavior, choice of a punishment for another participant ). reaction time. the time between the presentation of a stimulus and an appropriate response can indicate differences between two cognitive processes, and can indicate some things about their nature. for example, if in a search task the reaction times vary proportionally with the number of elements, then it is evident that this cognitive process of searching involves serial instead of parallel processing. psychophysical responses. psychophysical experiments are an old psychological technique, which has been adopted by cognitive psychology. they typically involve making judgments of some physical property, e. g. the loudness of a sound. correlation of subjective scales between individuals can show cognitive or sensory biases as compared to actual physical measurements. some examples include : sameness judgments for colors, tones, textures, etc. threshold differences for colors, tones, textures, etc. eye tracking. this methodology is used to study a variety of cognitive processes, most notably visual perception and language processing. the fixation point of the eyes is linked to an individual ' s focus of attention. thus, by monitoring eye movements, we can study what information is being processed at a given time. eye tracking allows us to study cognitive processes on extremely short time scales. eye movements reflect online decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), is not present ( e. g., litter in a parking lot or readings on an electric meter ). behavioral observations involve the direct witnessing of the actor engaging in the behavior ( e. g., watching how close a person sits next to another person ). behavioral choices are when a person selects between two or more options ( e. g., voting behavior, choice of a punishment for another participant ). reaction time. the time between the presentation of a stimulus and an appropriate response can indicate differences between two cognitive processes, and can indicate some things about their nature. for example, if in a search task the reaction times vary proportionally with the number of elements, then it is evident that this cognitive process of searching involves serial instead of parallel processing. psychophysical responses. psychophysical experiments are an old psychological technique, which has been adopted by cognitive psychology. they typically involve making judgments of some physical property, e. g. the loudness of a sound. correlation of subjective scales between individuals can show cognitive or sensory biases as compared to actual physical measurements. some examples include : sameness judgments for colors, tones, textures, etc. threshold differences for colors, tones, textures, etc. eye tracking. this methodology is used to study a variety of cognitive processes, most notably visual perception and language processing. the fixation point of the eyes is linked to an individual ' s focus of attention. thus, by monitoring eye movements, we can study what information is being processed at a given time. eye tracking allows us to study cognitive processes on extremely short time scales. eye movements reflect online decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream and taken up by the brain. by observing which areas of the brain take up the radioactive isotope, we can see which areas of the brain are more active than other areas. pet has similar spatial resolution to fmri, but it has extremely poor temporal resolution. electroencephalography. eeg measures the electrical fields within the military ranges from educational purposes, training exercises and sustainability technology. the technology used for educational purposes within the military are mainly wearables that tracks a soldier ' s vitals. by tracking a soldier ' s heart rate, blood pressure, emotional status, etc. helps the research and development team best help the soldiers. according to chemist, matt coppock, he has started to enhance a soldier ' s lethality by collecting different biorecognition receptors. by doing so it will eliminate emerging environmental threats to the soldiers. with the emergence of virtual reality it is only natural to start creating simulations using vr. this will better prepare the user for whatever situation they are training for. in the military there are combat simulations that soldiers will train on. the reason the military will use vr to train its soldiers is because it is the most interactive / immersive experience the user will feels without being put in a real situation. recent simulations include a soldier wearing a shock belt during a combat simulation. each time they are shot the belt will release a certain amount of electricity directly to the user ' s skin. this is to simulate a shot wound in the most humane way possible. there are many sustainability technologies that military personnel wear in the field. one of which is a boot insert. this insert gauges how soldiers are carrying the weight of their equipment and how daily terrain factors impact their mission panning optimization. these sensors will not only help the military plan the best timeline but will help keep the soldiers at best physical / mental health. = = fashion = = fashionable wearables are " designed garments and accessories that combines aesthetics and style with functional technology. " garments are the interface to the exterior mediated through digital technology. it allows endless possibilities for the dynamic customization of apparel. all clothes have social, psychological and physical functions. however, with the use of technology these functions can be amplified. there are some wearables that are called e - textiles. these are the combination of textiles ( fabric ) and electronic components to create wearable technology within clothing. they are also known as smart textile and digital textile. wearables are made from a functionality perspective or from an aesthetic perspective. when made from a functionality perspective, designers and engineers create wearables to provide convenience to the user. clothing and accessories are used as a tool to provide assistance to the user. designers and engineers are working together to incorporate technology in the manufacturing of garments in order to provide functionalities that can simplify the lives of the user. for example, through smartwatches blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of octet hyperon charge radii are calculated in a chiral constituent quark model including electromagnetic exchange currents between quarks. in impulse approximation one observes a decrease of the hyperon charge radii with increasing strangeness. this effect is reduced by exchange currents. due to exchange currents, the charge radius of the negatively charged hyperons are close to the proton charge radius. Question: In many species, display behaviors, like a gorilla beating on its chest, are used instead of actual physical attacks to show what? A) stress B) friction C) aggression D) dominance	C) aggression
Context: cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with support matrices for tissue engineering applications. an adequate environment for promoting cell growth, differentiation, and integration with the existing tissue is a critical factor for cell - based building blocks. manipulation of any of these cell processes create alternative avenues for the development of new tissue ( e. g., cell reprogramming - somatic cells, vascularization ). = = = isolation = = = techniques for cell isolation depend on the cell source. centrifugation and apheresis are techniques used for extracting cells from biofluids ( e. g., blood ). whereas digestion processes, typically using enzymes to remove the extra blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of this scaffold and cells were placed in a bioreactor, where it matured to become a partially or fully transplantable organ. the work was called a " landmark ". the lab first stripped the cells away from a rat heart ( a process called " decellularization " ) and then injected rat stem cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with support matrices for tissue engineering applications. an adequate environment for promoting cell growth, differentiation, and integration with the existing tissue is a critical factor for cell - based building blocks. manipulation of any of these cell processes create alternative avenues for the development of new tissue ( e. g., cell reprogramming - somatic tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues. tissue engineering often involves the use of cells placed on tissue scaffolds in the formation of new viable tissue for a medical purpose, but is not limited to applications involving cells and tissue scaffolds. while it was once categorized as a sub - field of biomaterials, having grown in scope and importance, it can be considered as a field of its own. while most definitions of tissue engineering cover a broad range of applications, in practice, the term is closely associated with applications that repair or replace portions of or whole tissues ( i. e. organs, bone, cartilage, blood vessels, bladder, skin, muscle etc. ). often, the tissues involved require certain mechanical and structural properties for proper functioning. the term has also been applied to efforts to perform specific biochemical functions using cells within an artificially - created support system ( e. g. an artificial pancreas, or a bio artificial liver ). the term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues. = = overview = = a commonly applied definition of tissue engineering, as stated by langer and vacanti, is " an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [ biological tissue ] function or a whole organ ". in addition, langer and vacanti also state that there are three main types of tissue engineering : cells, tissue - inducing substances, and a cells + matrix approach ( often referred to as a scaffold ). tissue engineering has also been defined as " understanding the principles of tissue growth, and applying this to produce functional replacement tissue for clinical use ". a further description goes on to say that an " underlying supposition of tissue engineering is that the employment of natural biology of the system will allow for greater success in developing therapeutic strategies aimed at the replacement, repair, maintenance, or enhancement of tissue function ". developments in the multidisciplinary field of tissue engineering have yielded a novel set of tissue replacement parts and implementation strategies. scientific advances in biomaterials, stem cells, growth and differentiation factors, and biomimetic environments have created unique opportunities to fabric ##ilage generated without the use of exogenous scaffold material. in this methodology, all material in the construct is cellular produced directly by the cells. bioartificial heart : doris taylor ' s lab constructed a biocompatible rat heart by re - cellularising a de - cellularised rat heart. this scaffold and cells were placed in a bioreactor, where it matured to become a partially or fully transplantable organ. the work was called a " landmark ". the lab first stripped the cells away from a rat heart ( a process called " decellularization " ) and then injected rat stem cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with unspecialised cells ) that can grow into a new plant. in vascular plants, the xylem and phloem are the conductive tissues that transport resources between shoots and roots. roots are often adapted to store food such as sugars or starch, as in sugar beets and carrots. stems mainly provide support to the leaves and reproductive structures, but can store water in succulent plants such as cacti, food as in potato tubers, or reproduce vegetatively as in the stolons of strawberry plants or in the process of layering. leaves gather sunlight and carry out photosynthesis. large, flat, flexible, green leaves are called foliage leaves. gymnosperms, such as conifers, cycads, ginkgo, and gnetophytes are seed - producing plants with open seeds. angiosperms are seed - producing plants that produce flowers and have enclosed seeds. woody plants, such as azaleas and oaks, undergo a secondary growth phase resulting in two additional types of tissues : wood ( secondary xylem ) and bark ( secondary phloem and cork ). all gymnosperms and many angiosperms are woody plants. some plants reproduce sexually, some asexually, and some via both means. although reference to major morphological categories such as root, stem, leaf, and trichome are useful, one has to keep in mind that these categories are linked through intermediate forms so that a continuum between the categories results. furthermore, structures can be seen as processes, that is, process combinations. = = systematic botany = = systematic botany is part of systematic biology, which is concerned with the range and diversity of organisms and their relationships, particularly as determined by their evolutionary history. it involves, or is related to, biological classification, scientific taxonomy and phylogenetics. biological classification is the method by which botanists group organisms into categories such as genera or species. biological classification is a form of scientific taxonomy. modern taxonomy is rooted in the work of carl linnaeus, who grouped species according to shared physical characteristics. these groupings have since been revised to align better with the darwinian principle of common descent – grouping organisms by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomi ##ta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. hetero 1975. skin tissue - engineered skin is a type of bioartificial organ that is often used to treat burns, diabetic foot ulcers, or other large wounds that cannot heal well on their own. artificial skin can be made from autografts, allografts, and xenografts. autografted skin comes from a patient ' s own skin, which allows the dermis to have a faster healing rate, and the donor site can be re - harvested a few times. allograft skin often comes from cadaver skin and is mostly used to treat burn victims. lastly, xenografted skin comes from animals and provides a temporary healing structure for the skin. they assist in dermal regeneration, but cannot become part of the host skin. tissue - engineered skin is now available in commercial products. integra, originally used to only treat burns, consists of a collagen matrix and chondroitin sulfate that can be used as a skin replacement. the chondroitin sulfate functions as a component of proteoglycans, which helps to form the extracellular matrix. integra can be repopulated and revascularized while maintaining its dermal collagen architecture, making it a bioartificial organ dermagraft, another commercial - made tissue - engineered skin product, is made out of living fibroblasts. these fibroblasts proliferate and produce growth factors, collagen, and ecm proteins, that help build granulation tissue. = = = = heart = = = = since the number of patients awaiting a heart transplant is continuously increasing over time, and the number of patients on the waiting list surpasses the organ availability, artificial organs used as replacement therapy for terminal heart failure would help alleviate this difficulty. artificial hearts are usually used to bridge the heart transplantation or can be applied as replacement therapy for terminal heart malfunction. the total artificial heart ( tah ), first introduced by dr. vladimir p. demikhov in 1937, emerged as an ideal alternative. since then it has been developed and improved as a mechanical pump that provides long - term circulatory support and replaces diseased or damaged heart ventricles that cannot properly pump the blood, restoring thus the pulmonary and systemic flow. some of the current tahs include abiocor, an fda - approved device that comprises two artificial ventricles and their valves, and does not require subcutaneous connections, and is indicated for as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase , characterizing organs as predominantly yin or yang, and understood the relationship between the pulse, the heart, and the flow of blood in the body centuries before it became accepted in the west. little evidence survives of how ancient indian cultures around the indus river understood nature, but some of their perspectives may be reflected in the vedas, a set of sacred hindu texts. they reveal a conception of the universe as ever - expanding and constantly being recycled and reformed. surgeons in the ayurvedic tradition saw health and illness as a combination of three humors : wind, bile and phlegm. a healthy life resulted from a balance among these humors. in ayurvedic thought, the body consisted of five elements : earth, water, fire, wind, and space. ayurvedic surgeons performed complex surgeries and developed a detailed understanding of human anatomy. pre - socratic philosophers in ancient greek culture brought natural philosophy a step closer to direct inquiry about cause and effect in nature between 600 and 400 bc. however, an element of magic and mythology remained. natural phenomena such as earthquakes and eclipses were explained increasingly in the context of nature itself instead of being attributed to angry gods. thales of miletus, an early philosopher who lived from 625 to 546 bc, explained earthquakes by theorizing that the world floated on water and that water was the fundamental element in nature. in the 5th century bc, leucippus was an early exponent of atomism, the idea that the world is made up of fundamental indivisible particles. pythagoras applied greek innovations in mathematics to astronomy and suggested that the earth was spherical. = = = aristotelian natural philosophy ( 400 bc – 1100 ad ) = = = later socratic and platonic thought focused on ethics, morals, and art and did not attempt an investigation of the physical world ; plato criticized pre - socratic thinkers as materialists and anti - religionists. aristotle, however, a student of plato who lived from 384 to 322 bc, paid closer attention to the natural world in his philosophy. in his history of animals, he described the inner workings of 110 species, including the stingray, catfish and bee. he investigated chick embryos by breaking open eggs and observing them at various stages of development. aristotle ' s works were influential through the 16th century, and he is considered to be the father of biology for his pioneering work in that science. he also presented philosophies about physics, nature, and astronomy using Question: What are the two types of vascular tissue? A) xylem and phloem B) cytoplasm and ectoplasm C) ectoderm and phloem D) phloem and phlegm	A) xylem and phloem
Context: participates as a consumer, resource, or both in consumer – resource interactions, which form the core of food chains or food webs. there are different trophic levels within any food web, with the lowest level being the primary producers ( or autotrophs ) such as plants and algae that convert energy and inorganic material into organic compounds, which can then be used by the rest of the community. at the next level are the heterotrophs, which are the species that obtain energy by breaking apart organic compounds from other organisms. heterotrophs that consume plants are primary consumers ( or herbivores ) whereas heterotrophs that consume herbivores are secondary consumers ( or carnivores ). and those that eat secondary consumers are tertiary consumers and so on. omnivorous heterotrophs are able to consume at multiple levels. finally, there are decomposers that feed on the waste products or dead bodies of organisms. on average, the total amount of energy incorporated into the biomass of a trophic level per unit of time is about one - tenth of the energy of the trophic level that it consumes. waste and dead material used by decomposers as well as heat lost from metabolism make up the other ninety percent of energy that is not consumed by the next trophic level. = = = biosphere = = = in the global ecosystem or biosphere, matter exists as different interacting compartments, which can be biotic or abiotic as well as accessible or inaccessible, depending on their forms and locations. for example, matter from terrestrial autotrophs are both biotic and accessible to other organisms whereas the matter in rocks and minerals are abiotic and inaccessible. a biogeochemical cycle is a pathway by which specific elements of matter are turned over or moved through the biotic ( biosphere ) and the abiotic ( lithosphere, atmosphere, and hydrosphere ) compartments of earth. there are biogeochemical cycles for nitrogen, carbon, and water. = = = conservation = = = conservation biology is the study of the conservation of earth ' s biodiversity with the aim of protecting species, their habitats, and ecosystems from excessive rates of extinction and the erosion of biotic interactions. it is concerned with factors that influence the maintenance, loss, and restoration of biodiversity and the science of sustaining evolutionary processes that engender genetic, population, species, and ecosystem diversity. the concern stems from estimates suggesting that up to 50 % of all species on the planet short - term, like pollination and predation, or long - term ; both often strongly influence the evolution of the species involved. a long - term interaction is called a symbiosis. symbioses range from mutualism, beneficial to both partners, to competition, harmful to both partners. every species participates as a consumer, resource, or both in consumer – resource interactions, which form the core of food chains or food webs. there are different trophic levels within any food web, with the lowest level being the primary producers ( or autotrophs ) such as plants and algae that convert energy and inorganic material into organic compounds, which can then be used by the rest of the community. at the next level are the heterotrophs, which are the species that obtain energy by breaking apart organic compounds from other organisms. heterotrophs that consume plants are primary consumers ( or herbivores ) whereas heterotrophs that consume herbivores are secondary consumers ( or carnivores ). and those that eat secondary consumers are tertiary consumers and so on. omnivorous heterotrophs are able to consume at multiple levels. finally, there are decomposers that feed on the waste products or dead bodies of organisms. on average, the total amount of energy incorporated into the biomass of a trophic level per unit of time is about one - tenth of the energy of the trophic level that it consumes. waste and dead material used by decomposers as well as heat lost from metabolism make up the other ninety percent of energy that is not consumed by the next trophic level. = = = biosphere = = = in the global ecosystem or biosphere, matter exists as different interacting compartments, which can be biotic or abiotic as well as accessible or inaccessible, depending on their forms and locations. for example, matter from terrestrial autotrophs are both biotic and accessible to other organisms whereas the matter in rocks and minerals are abiotic and inaccessible. a biogeochemical cycle is a pathway by which specific elements of matter are turned over or moved through the biotic ( biosphere ) and the abiotic ( lithosphere, atmosphere, and hydrosphere ) compartments of earth. there are biogeochemical cycles for nitrogen, carbon, and water. = = = conservation = = = conservation biology is the study of the conservation of earth ' s biodiversity with the aim of protecting species, their habitats, and ecosystems from excessive rates species occupying the same geographical area at the same time. a biological interaction is the effect that a pair of organisms living together in a community have on each other. they can be either of the same species ( intraspecific interactions ), or of different species ( interspecific interactions ). these effects may be short - term, like pollination and predation, or long - term ; both often strongly influence the evolution of the species involved. a long - term interaction is called a symbiosis. symbioses range from mutualism, beneficial to both partners, to competition, harmful to both partners. every species participates as a consumer, resource, or both in consumer – resource interactions, which form the core of food chains or food webs. there are different trophic levels within any food web, with the lowest level being the primary producers ( or autotrophs ) such as plants and algae that convert energy and inorganic material into organic compounds, which can then be used by the rest of the community. at the next level are the heterotrophs, which are the species that obtain energy by breaking apart organic compounds from other organisms. heterotrophs that consume plants are primary consumers ( or herbivores ) whereas heterotrophs that consume herbivores are secondary consumers ( or carnivores ). and those that eat secondary consumers are tertiary consumers and so on. omnivorous heterotrophs are able to consume at multiple levels. finally, there are decomposers that feed on the waste products or dead bodies of organisms. on average, the total amount of energy incorporated into the biomass of a trophic level per unit of time is about one - tenth of the energy of the trophic level that it consumes. waste and dead material used by decomposers as well as heat lost from metabolism make up the other ninety percent of energy that is not consumed by the next trophic level. = = = biosphere = = = in the global ecosystem or biosphere, matter exists as different interacting compartments, which can be biotic or abiotic as well as accessible or inaccessible, depending on their forms and locations. for example, matter from terrestrial autotrophs are both biotic and accessible to other organisms whereas the matter in rocks and minerals are abiotic and inaccessible. a biogeochemical cycle is a pathway by which specific elements of matter are turned over or moved through the biotic ( biosphere ) and the abiotic ( lithos is the scientific study of inheritance. mendelian inheritance, specifically, is the process by which genes and traits are passed on from parents to offspring. it has several principles. the first is that genetic characteristics, alleles, are discrete and have alternate forms ( e. g., purple vs. white or tall vs. dwarf ), each inherited from one of two parents. based on the law of dominance and uniformity, which states that some alleles are dominant while others are recessive ; an organism with at least one dominant allele will display the phenotype of that dominant allele. during gamete formation, the alleles for each gene segregate, so that each gamete carries only one allele for each gene. heterozygotic individuals produce gametes with an equal frequency of two alleles. finally, the law of independent assortment, states that genes of different traits can segregate independently during the formation of gametes, i. e., genes are unlinked. an exception to this rule would include traits that are sex - linked. test crosses can be performed to experimentally determine the underlying genotype of an organism with a dominant phenotype. a punnett square can be used to predict the results of a test cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can in 2015 the fda approved the first gm salmon for commercial production and consumption. there is a scientific consensus that currently available food derived from gm crops poses no greater risk to human health than conventional food, but that each gm food needs to be tested on a case - by - case basis before introduction. nonetheless, members of the public are much less likely than scientists to perceive gm foods as safe. the legal and regulatory status of gm foods varies by country, with some nations banning or restricting them, and others permitting them with widely differing degrees of regulation. gm crops also provide a number of ecological benefits, if not used in excess. insect - resistant crops have proven to lower pesticide usage, therefore reducing the environmental impact of pesticides as a whole. however, opponents have objected to gm crops per se on several grounds, including environmental concerns, whether food produced from gm crops is safe, whether gm crops are needed to address the world ' s food needs, and economic concerns raised by the fact these organisms are subject to intellectual property law. biotechnology has several applications in the realm of food security. crops like golden rice are engineered to have higher nutritional content, and there is potential for food products with longer shelf lives. though not a form of agricultural biotechnology, vaccines can help prevent diseases found in animal agriculture. additionally, agricultural biotechnology can expedite breeding processes in order to yield faster results and provide greater quantities of food. transgenic biofortification in cereals has been considered as a promising method to combat malnutrition in india and other countries. = = = industrial = = = industrial biotechnology ( known mainly in europe as white biotechnology ) is the application of biotechnology for industrial purposes, including industrial fermentation. it includes the practice of using cells such as microorganisms, or components of cells like enzymes, to generate industrially useful products in sectors such as chemicals, food and feed, detergents, paper and pulp, textiles and biofuels. in the current decades, significant progress has been done in creating genetically modified organisms ( gmos ) that enhance the diversity of applications and economical viability of industrial biotechnology. by using renewable raw materials to produce a variety of chemicals and fuels, industrial biotechnology is actively advancing towards lowering greenhouse gas emissions and moving away from a petrochemical - based economy. synthetic biology is considered one of the essential cornerstones in industrial biotechnology due to its financial and sustainable contribution to the manufacturing sector. jointly biotechnology and synthetic biology play a crucial role in generating cost - effective products with nature - friendly features by using bio - based of several methods used by plants to promote outcrossing. in many land plants the male and female gametes are produced by separate individuals. these species are said to be dioecious when referring to vascular plant sporophytes and dioicous when referring to bryophyte gametophytes. charles darwin in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in cytokinesis. this can occur early in development to produce an autopolyploid or partly autopolyploid organism, or during normal processes of cellular differentiation to produce some cell types that are polyploid ( endopolyploidy ), or during gamete formation. an allopolyploid plant may result from a hybridisation event between two different species. both autopolyploid and allopolyploid plants can often reproduce normally, but may be unable to cross - breed successfully with the parent population because there is a mismatch in chromosome numbers. these plants that are reproductively isolated from the parent in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in cytokinesis. this can occur early in development to produce an autopolyploid or partly autopolyploid organism, or during normal processes of cellular differentiation to produce some cell types that are polyploid ( endopolyploidy ), or during gamete formation. an allopolyploid plant may result from a hybridisation event between two different species. both autopolyploid and allopolyploid plants can often reproduce normally, but may be unable to cross - breed successfully with the parent population because there is a mismatch in chromosome numbers. these plants that are reproductively isolated from the parent species but live within the same geographical area, may be sufficiently successful to form a new species. some otherwise sterile plant polyploids can still reproduce vegetatively or by seed apomixis, forming clonal populations of identical individuals. durum wheat is a fertile tetraploid allopolyploid molecules and induce ionization ( hence the name ) which cannot be achieved by mere heating. this is the reason for new beneficial effects, however at the same time, for new concerns. the treatment of solid food by ionizing radiation can provide an effect similar to heat pasteurization of liquids, such as milk. however, the use of the term, cold pasteurization, to describe irradiated foods is controversial, because pasteurization and irradiation are fundamentally different processes, although the intended end results can in some cases be similar. detractors of food irradiation have concerns about the health hazards of induced radioactivity. a report for the industry advocacy group american council on science and health entitled " irradiated foods " states : " the types of radiation sources approved for the treatment of foods have specific energy levels well below that which would cause any element in food to become radioactive. food undergoing irradiation does not become any more radioactive than luggage passing through an airport x - ray scanner or teeth that have been x - rayed. " food irradiation is currently permitted by over 40 countries and volumes are estimated to exceed 500, 000 metric tons ( 490, 000 long tons ; 550, 000 short tons ) annually worldwide. food irradiation is essentially a non - nuclear technology ; it relies on the use of ionizing radiation which may be generated by accelerators for electrons and conversion into bremsstrahlung, but which may use also gamma - rays from nuclear decay. there is a worldwide industry for processing by ionizing radiation, the majority by number and by processing power using accelerators. food irradiation is only a niche application compared to medical supplies, plastic materials, raw materials, gemstones, cables and wires, etc. = = accidents = = nuclear accidents, because of the powerful forces involved, are often very dangerous. historically, the first incidents involved fatal radiation exposure. marie curie died from aplastic anemia which resulted from her high levels of exposure. two scientists, an american and canadian respectively, harry daghlian and louis slotin, died after mishandling the same plutonium mass. unlike conventional weapons, the intense light, heat, and explosive force is not the only deadly component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. civilian nuclear and radiological accidents primarily involve nuclear power plants. most common are nuclear leaks that expose workers to hazardous material. a nuclear meltdown refers to the more serious hazard of eat them. plants and other photosynthetic organisms are at the base of most food chains because they use the energy from the sun and nutrients from the soil and atmosphere, converting them into a form that can be used by animals. this is what ecologists call the first trophic level. the modern forms of the major staple foods, such as hemp, teff, maize, rice, wheat and other cereal grasses, pulses, bananas and plantains, as well as hemp, flax and cotton grown for their fibres, are the outcome of prehistoric selection over thousands of years from among wild ancestral plants with the most desirable characteristics. botanists study how plants produce food and how to increase yields, for example through plant breeding, making their work important to humanity ' s ability to feed the world and provide food security for future generations. botanists also study weeds, which are a considerable problem in agriculture, and the biology and control of plant pathogens in agriculture and natural ecosystems. ethnobotany is the study of the relationships between plants and people. when applied to the investigation of historical plant – people relationships ethnobotany may be referred to as archaeobotany or palaeoethnobotany. some of the earliest plant - people relationships arose between the indigenous people of canada in identifying edible plants from inedible plants. this relationship the indigenous people had with plants was recorded by ethnobotanists. = = plant biochemistry = = plant biochemistry is the study of the chemical processes used by plants. some of these processes are used in their primary metabolism like the photosynthetic calvin cycle and crassulacean acid metabolism. others make specialised materials like the cellulose and lignin used to build their bodies, and secondary products like resins and aroma compounds. plants and various other groups of photosynthetic eukaryotes collectively known as " algae " have unique organelles known as chloroplasts. chloroplasts are thought to be descended from cyanobacteria that formed endosymbiotic relationships with ancient plant and algal ancestors. chloroplasts and cyanobacteria contain the blue - green pigment chlorophyll a. chlorophyll a ( as well as its plant and green algal - specific cousin chlorophyll b ) absorbs light in the blue - violet and orange / red parts of the spectrum while reflecting and transmitting the green light that we see as the characteristic colour inter - and intra - specific crosses between wild species and their hybrids. angiosperms with monoecious flowers often have self - incompatibility mechanisms that operate between the pollen and stigma so that the pollen either fails to reach the stigma or fails to germinate and produce male gametes. this is one of several methods used by plants to promote outcrossing. in many land plants the male and female gametes are produced by separate individuals. these species are said to be dioecious when referring to vascular plant sporophytes and dioicous when referring to bryophyte gametophytes. charles darwin in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in cytokinesis. this can occur early in development to produce an autopolyploid or partly autopolyploid organism, or during normal processes of cellular differentiation to produce some cell types that are polyploid ( endopolyploidy ), or during gamete formation. an allopolyploid Question: Because heterotrophs cannot make their own food, what are they called? A) destroyers B) consumers C) products D) customers	B) consumers
Context: to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids are polymers of nucleotides. their function is to store, transmit, and express hereditary information. = = cells = = cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, and that all cells arise from preexisting cells through cell division. most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing ##tes, i. e., genes are unlinked. an exception to this rule would include traits that are sex - linked. test crosses can be performed to experimentally determine the underlying genotype of an organism with a dominant phenotype. a punnett square can be used to predict the results of a test cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna , there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support as well as being involved in reproduction and breakdown of plant seeds. eukaryotic cells also have cytoskeleton that is made up of microtubules, intermediate filaments, and microfilaments, all of which provide support for the cell and are involved in the movement of the cell and its organelles. in terms of their structural composition, the microtubules are made up of tubulin ( e. g., α - tubulin and β - tubulin ) whereas intermediate filaments are made up of fibrous proteins. microfilaments are made up of actin molecules that interact with other strands of proteins. = = = metabolism = = = all cells require energy to sustain cellular processes. metabolism is the set of chemical reactions in an organism. the three main purposes of metabolism are : the conversion of food to energy to run cellular processes ; the conversion of food / fuel to monomer building blocks ; and the elimination of metabolic wastes. these enzyme - catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. metabolic reactions may be categorized as catabolic — the breaking down of compounds ( for example, the breaking down of glucose to pyruvate by cellular respiration ) ; or anabolic — the building up ( synthesis ) of compounds ( such as proteins, carbohydrates, lipids, and nucleic acids ). usually, catabolism releases energy, and anabolism consumes energy. the chemical reactions of metabolism are organized into metabolic pathways, in which or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws some properties of the nuclear matter as revealed by cherenkov gluons are discussed. . in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes of homologous recombination and nonhomologous end - joining. there are four families of engineered nucleases : meganucleases, zinc finger nucleases, transcription activator - like effector nucleases ( talens ), and the cas9 - guiderna system ( adapted from crispr ). talen and crispr are the two most commonly used and each has its own advantages. talens have greater target specificity, while crispr is easier to design and more efficient. in addition to enhancing gene targeting, engineered nucleases can be used to introduce mutations at endogenous genes that generate a gene knockout. = = applications = = genetic engineering has applications in medicine, research, industry and agriculture and can be used on a wide range of plants, animals and microorganisms. bacteria, the first organisms to be genetically modified, can have plasmid dna inserted not always mean it is required, especially when dealing with genetic or functional redundancy. tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. one way to do this is to replace the wild - type gene with a ' fusion ' gene, which is a juxtaposition of the wild - type gene with a reporting element such as green fluorescent protein ( gfp ) that will allow easy visualisation of the products of the genetic modification. while this is a useful technique, the manipulation can destroy the function of the gene, creating secondary effects and possibly calling into question the results of the experiment. more sophisticated techniques are now in development that can track protein products without mitigating their function, such as the addition of small sequences that will serve as binding motifs to monoclonal antibodies. expression studies aim to discover where and when specific proteins are produced. in these experiments, the dna sequence before the dna that codes for a protein, known as a gene ' s promoter, is reintroduced into an organism with the protein coding region replaced by a reporter gene such as gfp or an enzyme that catalyses the production of a dye. thus the time and place where a particular protein is produced can be observed. expression studies can be taken a step further by altering the promoter to find which pieces are crucial for the proper expression of the gene and are actually bound by transcription factor proteins ; this process is known as promoter bashing. = = = industrial = = = organisms can have their cells transformed with a gene coding for a useful protein, such as an enzyme, so that they will overexpress the desired protein. mass quantities of the protein can then be manufactured by growing the transformed organism in bioreactor equipment using industrial fermentation, and then purifying the protein. some genes do not work well in bacteria, so yeast, insect cells or mammalian cells can also be used. these techniques are used to produce medicines such as insulin, human growth hormone, and vaccines, supplements such as tryptophan, aid in the production of food ( chymosin in cheese making ) and fuels. other applications with genetically engineered bacteria could involve making them perform tasks outside their natural cycle, such as making biofuels, cleaning up oil spills, carbon and other toxic waste and detecting arsenic in drinking water. certain genetically modified microbes can also be used in biomining and bioremediation, due to their ability to extract heavy metals from their environment and incorporate them into compounds that are more easily recover defective gene with a functioning one. it is an important tool in research that allows the function of specific genes to be studied. drugs, vaccines and other products have been harvested from organisms engineered to produce them. crops have been developed that aid food security by increasing yield, nutritional value and tolerance to environmental stresses. the dna can be introduced directly into the host organism or into a cell that is then fused or hybridised with the host. this relies on recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro - injection, macro - injection or micro - encapsulation. genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. however, some broad definitions of genetic engineering include selective breeding. cloning and stem cell research, although not considered genetic engineering, are closely related and genetic engineering can be used within them. synthetic biology is an emerging discipline that takes genetic engineering a step further by introducing artificially synthesised material into an organism. plants, animals or microorganisms that have been changed through genetic engineering are termed genetically modified organisms or gmos. if genetic material from another species is added to the host, the resulting organism is called transgenic. if genetic material from the same species or a species that can naturally breed with the host is used the resulting organism is called cisgenic. if genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a knockout organism. in europe genetic modification is synonymous with genetic engineering while within the united states of america and canada genetic modification can also be used to refer to more conventional breeding methods. = = history = = humans have altered the genomes of species for thousands of years through selective breeding, or artificial selection : 1 : 1 as contrasted with natural selection. more recently, mutation breeding has used exposure to chemicals or radiation to produce a high frequency of random mutations, for selective breeding purposes. genetic engineering as the direct manipulation of dna by humans outside breeding and mutations has only existed since the 1970s. the term " genetic engineering " was coined by the russian - born geneticist nikolay timofeev - ressovsky in his 1934 paper " the experimental production of mutations ", published in the british journal biological reviews. jack williamson used the term in his science fiction novel dragon ' Question: Nucleic acids contain the information needed for cells to make what? A) lipids B) proteins C) metabolytes D) protons	B) proteins
Context: , 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans also had a complex system of aqueducts, which were used to transport water across long distances. the first roman aqueduct was built in 312 bce. the eleventh and final ancient roman aqueduct was built in 226 ce. put together, the roman aqueducts extended over 450 km, but less than 70 km of this was above ground and supported by arches. = = = pre - modern = = = innovations continued through the middle ages with the introduction of silk production ( in asia and later europe ), the horse collar, and horseshoes. simple machines ( such as the lever, the screw, and the pulley ) were combined into more complicated tools, such as the wheelbarrow, windmills, and clocks. a system of universities developed and spread scientific ideas and practices, including oxford and cambridge. the renaissance era produced many innovations, including the introduction of the movable type printing press to europe, which facilitated the communication of knowledge. technology became increasingly influenced by science, beginning a cycle of mutual advancement. = = = modern = = = starting in the united kingdom in the 18th century, the discovery of steam power set off the industrial revolution, which saw wide - ranging technological discoveries, particularly in the areas of agriculture, manufacturing, mining, metallurgy, and transport, and the widespread application of the factory system. this was followed a century later by the second industrial revolution which led to rapid scientific discovery, standardization, and mass production. new technologies were developed, including sewage systems, electricity, light bulbs, electric motors, railroads, automobiles, and airplanes. these technological advances led to significant developments in medicine dissipation. as well as making for highly repeatable motion, this also makes silicon very reliable as it suffers very little fatigue and can have service lifetimes in the range of billions to trillions of cycles without breaking. semiconductor nanostructures based on silicon are gaining increasing importance in the field of microelectronics and mems in particular. silicon nanowires, fabricated through the thermal oxidation of silicon, are of further interest in electrochemical conversion and storage, including nanowire batteries and photovoltaic systems. polymers even though the electronics industry provides an economy of scale for the silicon industry, crystalline silicon is still a complex and relatively expensive material to produce. polymers on the other hand can be produced in huge volumes, with a great variety of material characteristics. mems devices can be made from polymers by processes such as injection molding, embossing or stereolithography and are especially well suited to microfluidic applications such as disposable blood testing cartridges. metals metals can also be used to create mems elements. while metals do not have some of the advantages displayed by silicon in terms of mechanical properties, when used within their limitations, metals can exhibit very high degrees of reliability. metals can be deposited by electroplating, evaporation, and sputtering processes. commonly used metals include gold, nickel, aluminium, copper, chromium, titanium, tungsten, platinum, and silver. ceramics the nitrides of silicon, aluminium and titanium as well as silicon carbide and other ceramics are increasingly applied in mems fabrication due to advantageous combinations of material properties. aln crystallizes in the wurtzite structure and thus shows pyroelectric and piezoelectric properties enabling sensors, for instance, with sensitivity to normal and shear forces. tin, on the other hand, exhibits a high electrical conductivity and large elastic modulus, making it possible to implement electrostatic mems actuation schemes with ultrathin beams. moreover, the high resistance of tin against biocorrosion qualifies the material for applications in biogenic environments. the figure shows an electron - microscopic picture of a mems biosensor with a 50 nm thin bendable tin beam above a tin ground plate. both can be driven as opposite electrodes of a capacitor, since the beam is fixed in electrically isolating side walls. when a fluid is suspended in the cavity its viscosity may be derived from bending the beam by electrical attraction to the ground aquatic and most of the aquatic photosynthetic eukaryotic organisms are collectively described as algae, which is a term of convenience as not all algae are closely related. algae comprise several distinct clades such as glaucophytes, which are microscopic freshwater algae that may have resembled in form to the early unicellular ancestor of plantae. unlike glaucophytes, the other algal clades such as red and green algae are multicellular. green algae comprise three major clades : chlorophytes, coleochaetophytes, and stoneworts. fungi are eukaryotes that digest foods outside their bodies, secreting digestive enzymes that break down large food molecules before absorbing them through their cell membranes. many fungi are also saprobes, feeding on dead organic matter, making them important decomposers in ecological systems. animals are multicellular eukaryotes. with few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea. more than 6, 000 virus species have been described in detail. viruses are found in almost every ecosystem on earth and are the most numerous type of biological entity. the origins of viruses in the evolutionary history of life are unclear : some may have evolved from plasmids — pieces of dna that can move between cells — while others may have evolved from bacteria. in evolution, viruses are an important means of horizontal gene transfer, which increases genetic diversity in a way analogous to sexual reproduction. because viruses possess some but not all characteristics of life, they have been described as " organisms at the edge of life ", and as self - replicators. = = ecology = = ecology is the study of the distribution and abundance of life, the interaction between organisms and their environment. = = = ecosystems = = = the community of living ( biotic ) organisms in conjunction with the nonliving ( abiotic ) components ( e. ##rozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokar onset of electro - chemical corrosion. similar problems are encountered in coastal and offshore structures. = = = anti - fouling = = = anti - fouling is the process of eliminating obstructive organisms from essential components of seawater systems. depending on the nature and location of marine growth, this process is performed in a number of different ways : marine organisms may grow and attach to the surfaces of the outboard suction inlets used to obtain water for cooling systems. electro - chlorination involves running high electrical current through sea water, altering the water ' s chemical composition to create sodium hypochlorite, purging any bio - matter. an electrolytic method of anti - fouling involves running electrical current through two anodes ( scardino, 2009 ). these anodes typically consist of copper and aluminum ( or alternatively, iron ). the first metal, copper anode, releases its ion into the water, creating an environment that is too toxic for bio - matter. the second metal, aluminum, coats the inside of the pipes to prevent corrosion. other forms of marine growth such as mussels and algae may attach themselves to the bottom of a ship ' s hull. this growth interferes with the smoothness and uniformity of the ship ' s hull, causing the ship to have a less hydrodynamic shape that causes it to be slower and less fuel - efficient. marine growth on the hull can be remedied by using special paint that prevents the growth of such organisms. = = = pollution control = = = = = = = sulfur emission = = = = the burning of marine fuels releases harmful pollutants into the atmosphere. ships burn marine diesel in addition to heavy fuel oil. heavy fuel oil, being the heaviest of refined oils, releases sulfur dioxide when burned. sulfur dioxide emissions have the potential to raise atmospheric and ocean acidity causing harm to marine life. however, heavy fuel oil may only be burned in international waters due to the pollution created. it is commercially advantageous due to the cost effectiveness compared to other marine fuels. it is prospected that heavy fuel oil will be phased out of commercial use by the year 2020 ( smith, 2018 ). = = = = oil and water discharge = = = = water, oil, and other substances collect at the bottom of the ship in what is known as the bilge. bilge water is pumped overboard, but must pass a pollution threshold test of 15 ppm ( parts per million ) of oil to be discharged. water is tested the group velocity of light has been measured at eight different wavelengths between 385 nm and 532 nm in the mediterranean sea at a depth of about 2. 2 km with the antares optical beacon systems. a parametrisation of the dependence of the refractive index on wavelength based on the salinity, pressure and temperature of the sea water at the antares site is in good agreement with these measurements. the model of neutrino mass matrix with minimal texture is now tightly constrained by experiment so that it can yield a prediction for the phase of cp violation. this phase is predicted to lie in the range $ \ delta _ { cp } = 0. 77 \ pi - 1. 24 \ pi $. if neutrino oscillation experiment would find the cp violation phase outside this range, this means that the minimal - texture neutrino mass matrix, the element of which is all real, fails and the neutrino mass matrix must be complex, i. e., the phase must be present that is responsible for leptogenesis. a 4mj planet with a 15. 8day orbital period has been detected from very precise radial velocity measurements with the coralie echelle spectrograph. a second remote and more massive companion has also been detected. all the planetary companions so far detected in orbit closer than 0. 08 au have a parent star with a statistically higher metal content compared to the metallicity distribution of other stars with planets. different processes occuring during their formation may provide a possible explanation for this observation. this paper deals with a problem in which two players share a previously sliced pizza and try to eat as much amount of pizza as they can. it takes time to eat each piece of pizza and both players eat pizza at the same rate. one is allowed to take a next piece only after the person has finished eating the piece on hand. also, after the first piece is taken, one can only take a piece which is adjacent to already - taken piece. this paper shows that, in this real time setting, the starting player can always eat at least two - fifth of the total size of the pizza. however, this may not be the best possible amount the starting player can eat. it is a modified problem from an original one where two players takes piece alternatively instead. ) of the mass of all organisms, with calcium, phosphorus, sulfur, sodium, chlorine, and magnesium constituting essentially all the remainder. different elements can combine to form compounds such as water, which is fundamental to life. biochemistry is the study of chemical processes within and relating to living organisms. molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including molecular synthesis, modification, mechanisms, and interactions. = = = water = = = life arose from the earth ' s first ocean, which formed some 3. 8 billion years ago. since then, water continues to be the most abundant molecule in every organism. water is important to life because it is an effective solvent, capable of dissolving solutes such as sodium and chloride ions or other small molecules to form an aqueous solution. once dissolved in water, these solutes are more likely to come in contact with one another and therefore take part in chemical reactions that sustain life. in terms of its molecular structure, water is a small polar molecule with a bent shape formed by the polar covalent bonds of two hydrogen ( h ) atoms to one oxygen ( o ) atom ( h2o ). because the o – h bonds are polar, the oxygen atom has a slight negative charge and the two hydrogen atoms have a slight positive charge. this polar property of water allows it to attract other water molecules via hydrogen bonds, which makes water cohesive. surface tension results from the cohesive force due to the attraction between molecules at the surface of the liquid. water is also adhesive as it is able to adhere to the surface of any polar or charged non - water molecules. water is denser as a liquid than it is as a solid ( or ice ). this unique property of water allows ice to float above liquid water such as ponds, lakes, and oceans, thereby insulating the liquid below from the cold air above. water has the capacity to absorb energy, giving it a higher specific heat capacity than other solvents such as ethanol. thus, a large amount of energy is needed to break the hydrogen bonds between water molecules to convert liquid water into water vapor. as a molecule, water is not completely stable as each water molecule continuously dissociates into hydrogen and hydroxyl ions before reforming into a water molecule again. in pure water, the number of hydrogen ions balances ( or equals ) the number of hydroxyl ions, resulting in a ph that is neutral. = = = organic compounds = Question: Unlike corals, jellyfish spend most of their lives as what? A) pupae B) cercariae C) medusae D) infants	C) medusae
Context: ##itive material by selective exposure to a radiation source such as light. a photosensitive material is a material that experiences a change in its physical properties when exposed to a radiation source. if a photosensitive material is selectively exposed to radiation ( e. g. by masking some of the radiation ) the pattern of the radiation on the material is transferred to the material exposed, as the properties of the exposed and unexposed regions differs. this exposed region can then be removed or treated providing a mask for the underlying substrate. photolithography is typically used with metal or other thin film deposition, wet and dry etching. sometimes, photolithography is used to create structure without any kind of post etching. one example is su8 based lens where su8 based square blocks are generated. then the photoresist is melted to form a semi - sphere which acts as a lens. electron beam lithography ( often abbreviated as e - beam lithography ) is the practice of scanning a beam of electrons in a patterned fashion across a surface covered with a film ( called the resist ), ( " exposing " the resist ) and of selectively removing either exposed or non - exposed regions of the resist ( " developing " ). the purpose, as with photolithography, is to create very small structures in the resist that can subsequently be transferred to the substrate material, often by etching. it was developed for manufacturing integrated circuits, and is also used for creating nanotechnology architectures. the primary advantage of electron beam lithography is that it is one of the ways to beat the diffraction limit of light and make features in the nanometer range. this form of maskless lithography has found wide usage in photomask - making used in photolithography, low - volume production of semiconductor components, and research & development. the key limitation of electron beam lithography is throughput, i. e., the very long time it takes to expose an entire silicon wafer or glass substrate. a long exposure time leaves the user vulnerable to beam drift or instability which may occur during the exposure. also, the turn - around time for reworking or re - design is lengthened unnecessarily if the pattern is not being changed the second time. it is known that focused - ion beam lithography has the capability of writing extremely fine lines ( less than 50 nm line and space has been achieved ) without proximity effect. however, because the writing field in ion - beam lit is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the ability of cells to receive, process, and transmit signals with its environment and with itself. signals can be non - chemical such as light, electrical impulses, and heat, or chemical signals ( or ligands ) that interact with receptors, which can be found embedded in the cell membrane of another cell or located deep inside the radiation on the material is transferred to the material exposed, as the properties of the exposed and unexposed regions differs. this exposed region can then be removed or treated providing a mask for the underlying substrate. photolithography is typically used with metal or other thin film deposition, wet and dry etching. sometimes, photolithography is used to create structure without any kind of post etching. one example is su8 based lens where su8 based square blocks are generated. then the photoresist is melted to form a semi - sphere which acts as a lens. electron beam lithography ( often abbreviated as e - beam lithography ) is the practice of scanning a beam of electrons in a patterned fashion across a surface covered with a film ( called the resist ), ( " exposing " the resist ) and of selectively removing either exposed or non - exposed regions of the resist ( " developing " ). the purpose, as with photolithography, is to create very small structures in the resist that can subsequently be transferred to the substrate material, often by etching. it was developed for manufacturing integrated circuits, and is also used for creating nanotechnology architectures. the primary advantage of electron beam lithography is that it is one of the ways to beat the diffraction limit of light and make features in the nanometer range. this form of maskless lithography has found wide usage in photomask - making used in photolithography, low - volume production of semiconductor components, and research & development. the key limitation of electron beam lithography is throughput, i. e., the very long time it takes to expose an entire silicon wafer or glass substrate. a long exposure time leaves the user vulnerable to beam drift or instability which may occur during the exposure. also, the turn - around time for reworking or re - design is lengthened unnecessarily if the pattern is not being changed the second time. it is known that focused - ion beam lithography has the capability of writing extremely fine lines ( less than 50 nm line and space has been achieved ) without proximity effect. however, because the writing field in ion - beam lithography is quite small, large area patterns must be created by stitching together the small fields. ion track technology is a deep cutting tool with a resolution limit around 8 nm applicable to radiation resistant minerals, glasses and polymers. it is capable of generating holes in thin films without any development process. structural depth can be defined polymer diodes require cathodes that do not corrode the polymer but do have low work function to minimize the electron injection barrier. first - principles calculations demonstrate that the work function of the ( 1000 ) surface of the compound ca2n is half an ev lower than that of the elemental metal ca ( 2. 35 vs. 2. 87 ev ). moreover its reactivity is expected to be smaller. this makes ca2n an interesting candidate to replace calcium as cathode material for polymer light emitting diode devices. the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the ability of cells to receive, process, and transmit signals with its environment and with itself. signals can be non - chemical such as light, electrical impulses, and heat, or chemical signals ( or ligands ) that interact with receptors, which can be found embedded in the cell membrane of another cell or located deep inside a cell. there are generally four types of chemical signals : autocrine, paracrine, juxtacrine, and hormones. in autocrine signaling, the ligand affects the same cell that releases it. tumor cells, for example, can reproduce uncontrollably because they release signals that initiate their still a complex and relatively expensive material to produce. polymers on the other hand can be produced in huge volumes, with a great variety of material characteristics. mems devices can be made from polymers by processes such as injection molding, embossing or stereolithography and are especially well suited to microfluidic applications such as disposable blood testing cartridges. metals metals can also be used to create mems elements. while metals do not have some of the advantages displayed by silicon in terms of mechanical properties, when used within their limitations, metals can exhibit very high degrees of reliability. metals can be deposited by electroplating, evaporation, and sputtering processes. commonly used metals include gold, nickel, aluminium, copper, chromium, titanium, tungsten, platinum, and silver. ceramics the nitrides of silicon, aluminium and titanium as well as silicon carbide and other ceramics are increasingly applied in mems fabrication due to advantageous combinations of material properties. aln crystallizes in the wurtzite structure and thus shows pyroelectric and piezoelectric properties enabling sensors, for instance, with sensitivity to normal and shear forces. tin, on the other hand, exhibits a high electrical conductivity and large elastic modulus, making it possible to implement electrostatic mems actuation schemes with ultrathin beams. moreover, the high resistance of tin against biocorrosion qualifies the material for applications in biogenic environments. the figure shows an electron - microscopic picture of a mems biosensor with a 50 nm thin bendable tin beam above a tin ground plate. both can be driven as opposite electrodes of a capacitor, since the beam is fixed in electrically isolating side walls. when a fluid is suspended in the cavity its viscosity may be derived from bending the beam by electrical attraction to the ground plate and measuring the bending velocity. = = basic processes = = = = = deposition processes = = = one of the basic building blocks in mems processing is the ability to deposit thin films of material with a thickness anywhere from one micrometre to about 100 micrometres. the nems process is the same, although the measurement of film deposition ranges from a few nanometres to one micrometre. there are two types of deposition processes, as follows. = = = = physical deposition = = = = physical vapor deposition ( " pvd " ) consists of a process in which a material is removed from a target, and the film is developed and it shows any internal defects of the material. gauges - gauges use the exponential absorption law of gamma rays level indicators : source and detector are placed at opposite sides of a container, indicating the presence or absence of material in the horizontal radiation path. beta or gamma sources are used, depending on the thickness and the density of the material to be measured. the method is used for containers of liquids or of grainy substances thickness gauges : if the material is of constant density, the signal measured by the radiation detector depends on the thickness of the material. this is useful for continuous production, like of paper, rubber, etc. electrostatic control - to avoid the build - up of static electricity in production of paper, plastics, synthetic textiles, etc., a ribbon - shaped source of the alpha emitter 241am can be placed close to the material at the end of the production line. the source ionizes the air to remove electric charges on the material. radioactive tracers - since radioactive isotopes behave, chemically, mostly like the inactive element, the behavior of a certain chemical substance can be followed by tracing the radioactivity. examples : adding a gamma tracer to a gas or liquid in a closed system makes it possible to find a hole in a tube. adding a tracer to the surface of the component of a motor makes it possible to measure wear by measuring the activity of the lubricating oil. oil and gas exploration - nuclear well logging is used to help predict the commercial viability of new or existing wells. the technology involves the use of a neutron or gamma - ray source and a radiation detector which are lowered into boreholes to determine the properties of the surrounding rock such as porosity and lithography. [ 1 ] road construction - nuclear moisture / density gauges are used to determine the density of soils, asphalt, and concrete. typically a cesium - 137 source is used. = = = commercial applications = = = radioluminescence tritium illumination : tritium is used with phosphor in rifle sights to increase nighttime firing accuracy. some runway markers and building exit signs use the same technology, to remain illuminated during blackouts. betavoltaics. smoke detector : an ionization smoke detector includes a tiny mass of radioactive americium - 241, which is a source of alpha radiation. two ionisation chambers are placed next to each other. both contain a small source of 241am that gives rise to a small constant current. one is closed and serves for comparison , etc. electrostatic control - to avoid the build - up of static electricity in production of paper, plastics, synthetic textiles, etc., a ribbon - shaped source of the alpha emitter 241am can be placed close to the material at the end of the production line. the source ionizes the air to remove electric charges on the material. radioactive tracers - since radioactive isotopes behave, chemically, mostly like the inactive element, the behavior of a certain chemical substance can be followed by tracing the radioactivity. examples : adding a gamma tracer to a gas or liquid in a closed system makes it possible to find a hole in a tube. adding a tracer to the surface of the component of a motor makes it possible to measure wear by measuring the activity of the lubricating oil. oil and gas exploration - nuclear well logging is used to help predict the commercial viability of new or existing wells. the technology involves the use of a neutron or gamma - ray source and a radiation detector which are lowered into boreholes to determine the properties of the surrounding rock such as porosity and lithography. [ 1 ] road construction - nuclear moisture / density gauges are used to determine the density of soils, asphalt, and concrete. typically a cesium - 137 source is used. = = = commercial applications = = = radioluminescence tritium illumination : tritium is used with phosphor in rifle sights to increase nighttime firing accuracy. some runway markers and building exit signs use the same technology, to remain illuminated during blackouts. betavoltaics. smoke detector : an ionization smoke detector includes a tiny mass of radioactive americium - 241, which is a source of alpha radiation. two ionisation chambers are placed next to each other. both contain a small source of 241am that gives rise to a small constant current. one is closed and serves for comparison, the other is open to ambient air ; it has a gridded electrode. when smoke enters the open chamber, the current is disrupted as the smoke particles attach to the charged ions and restore them to a neutral electrical state. this reduces the current in the open chamber. when the current drops below a certain threshold, the alarm is triggered. = = = food processing and agriculture = = = in biology and agriculture, radiation is used to induce mutations to produce new or improved species, such as in atomic gardening. another use in insect control is the sterile insect technique, where male insects are sterilized by radiation and released, so they have the rapidly developing research field of organic analogue sensors aims to replace traditional semiconductors with naturally occurring materials. photosensors, or photodetectors, change their electrical properties in response to the light levels they are exposed to. organic photosensors can be functionalised to respond to specific wavelengths, from ultra - violet to red light. performing cyclic voltammetry on fungal mycelium and fruiting bodies under different lighting conditions shows no appreciable response to changes in lighting condition. however, functionalising the specimen using pedot : pss yields in a photosensor that produces large, instantaneous current spikes when the light conditions change. future works would look at interfacing this organic photosensor with an appropriate digital back - end for interpreting and processing the response. of measuring methods. x - rays and gamma rays are used in industrial radiography to make images of the inside of solid products, as a means of nondestructive testing and inspection. the piece to be radiographed is placed between the source and a photographic film in a cassette. after a certain exposure time, the film is developed and it shows any internal defects of the material. gauges - gauges use the exponential absorption law of gamma rays level indicators : source and detector are placed at opposite sides of a container, indicating the presence or absence of material in the horizontal radiation path. beta or gamma sources are used, depending on the thickness and the density of the material to be measured. the method is used for containers of liquids or of grainy substances thickness gauges : if the material is of constant density, the signal measured by the radiation detector depends on the thickness of the material. this is useful for continuous production, like of paper, rubber, etc. electrostatic control - to avoid the build - up of static electricity in production of paper, plastics, synthetic textiles, etc., a ribbon - shaped source of the alpha emitter 241am can be placed close to the material at the end of the production line. the source ionizes the air to remove electric charges on the material. radioactive tracers - since radioactive isotopes behave, chemically, mostly like the inactive element, the behavior of a certain chemical substance can be followed by tracing the radioactivity. examples : adding a gamma tracer to a gas or liquid in a closed system makes it possible to find a hole in a tube. adding a tracer to the surface of the component of a motor makes it possible to measure wear by measuring the activity of the lubricating oil. oil and gas exploration - nuclear well logging is used to help predict the commercial viability of new or existing wells. the technology involves the use of a neutron or gamma - ray source and a radiation detector which are lowered into boreholes to determine the properties of the surrounding rock such as porosity and lithography. [ 1 ] road construction - nuclear moisture / density gauges are used to determine the density of soils, asphalt, and concrete. typically a cesium - 137 source is used. = = = commercial applications = = = radioluminescence tritium illumination : tritium is used with phosphor in rifle sights to increase nighttime firing accuracy. some runway markers and building exit signs use the same technology, to remain illuminated during blackouts. betavoltaics Question: What are materials that eject electrons when illuminated with light called? A) fragmentation B) illumination C) photoemissive D) photogenic	C) photoemissive
Context: = = organic compounds are molecules that contain carbon bonded to another element such as hydrogen. with the exception of water, nearly all the molecules that make up each organism contain carbon. carbon can form covalent bonds with up to four other atoms, enabling it to form diverse, large, and complex molecules. for example, a single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such as octane or ring - like structures such as glucose. the simplest form of an organic molecule is the hydrocarbon, which is a large family of organic compounds that are composed of hydrogen atoms bonded to a chain of carbon atoms. a hydrocarbon backbone can be substituted by other elements such as oxygen ( o ), hydrogen ( h ), phosphorus ( p ), and sulfur ( s ), which can change the chemical behavior of that compound. groups of atoms that contain these elements ( o -, h -, p -, and s - ) and are bonded to a central carbon atom or skeleton are called functional groups. there are six prominent functional groups that can be found in organisms : amino group, carboxyl group, carbonyl group, hydroxyl group, phosphate group, and sulfhydryl group. in 1953, the miller – urey experiment showed that organic compounds could be synthesized abiotically within a closed system mimicking the conditions of early earth, thus suggesting that complex organic molecules could have arisen spontaneously in early earth ( see abiogenesis ). = = = macromolecules = = = macromolecules are large molecules made up of smaller subunits or monomers. monomers include sugars, amino acids, and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids a letter to the editor shortly summing up ten or so years of research into the h - index. or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for high quality thread. the power loom was invented by edmund cartwright in 1787. in the mid - 1750s, the steam engine was applied to the water power - constrained iron, copper and lead industries for powering blast bellows. these industries were located near the mines, some of which were using steam engines for mine pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, notably by richard roberts and joseph whitworth. the development of interchangeable parts through what is now called the american system of manufacturing began in the firearms industry at the u. s. federal arsenals in the early 19th century, and became widely used by the end of the century. until the enlightenment era, little progress was made in water supply and sanitation and the engineering skills of the romans were largely neglected throughout europe. the first documented use of sand filters to purify the water supply dates to 1804, when the owner of a bleachery in paisley, scotland, john gibb, installed an experimental filter, selling his unwanted shuttle from the heat of re - entry into the earth ' s atmosphere. one example is reinforced carbon - carbon ( rcc ), the light gray material, which withstands re - entry temperatures up to 1, 510 °c ( 2, 750 °f ) and protects the space shuttle ' s wing leading edges and nose cap. rcc is a laminated composite material made from graphite rayon cloth and impregnated with a phenolic resin. after curing at high temperature in an autoclave, the laminate is pyrolized to convert the resin to carbon, impregnated with furfuryl alcohol in a vacuum chamber, and cured - pyrolized to convert the furfuryl alcohol to carbon. to provide oxidation resistance for reusability, the outer layers of the rcc are converted to silicon carbide. other examples can be seen in the " plastic " casings of television sets, cell - phones and so on. these plastic casings are usually a composite material made up of a thermoplastic matrix such as acrylonitrile butadiene styrene ( abs ) in which calcium carbonate chalk, talc, glass fibers or carbon fibers have been added for added strength, bulk, or electrostatic dispersion. these additions may be termed reinforcing fibers, or dispersants, depending on their purpose. = = = polymers = = = polymers are chemical compounds made up of a large number of identical components linked together like chains. polymers are the raw materials ( the resins ) used to make what are commonly called plastics and rubber. plastics and rubber are the final product, created after one or more polymers or additives have been added to a resin during processing, which is then shaped into a final form. plastics in former and in current widespread use include polyethylene, polypropylene, polyvinyl chloride ( pvc ), polystyrene, nylons, polyesters, acrylics, polyurethanes, and polycarbonates. rubbers include natural rubber, styrene - butadiene rubber, chloroprene, and butadiene rubber. plastics are generally classified as commodity, specialty and engineering plastics. polyvinyl chloride ( pvc ) is widely used, inexpensive, and annual production quantities are large. it lends itself to a vast array of applications, from artificial leather to electrical insulation and cabling, packaging, and containers. its fabrication and processing are simple and well - established. high temperature superconducting ( hts ) tape can be cut and stacked to generate large magnetic fields at cryogenic temperatures after inducing persistent currents in the superconducting layers. a field of 17. 7 t was trapped between two stacks of hts tape at 8 k with no external mechanical reinforcement. 17. 6 t could be sustained when warming the stack up to 14 k. a new type of hybrid stack was used consisting of a 12 mm square insert stack embedded inside a larger 34. 4 mm diameter stack made from different tape. the magnetic field generated is the largest for any trapped field magnet reported and 30 % greater than previously achieved in a stack of hts tapes. such stacks are being considered for superconducting motors as rotor field poles where the cryogenic penalty is justified by the increased power to weight ratio. the sample reported can be considered the strongest permanent magnet ever created. single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such as octane or ring - like structures such as glucose. the simplest form of an organic molecule is the hydrocarbon, which is a large family of organic compounds that are composed of hydrogen atoms bonded to a chain of carbon atoms. a hydrocarbon backbone can be substituted by other elements such as oxygen ( o ), hydrogen ( h ), phosphorus ( p ), and sulfur ( s ), which can change the chemical behavior of that compound. groups of atoms that contain these elements ( o -, h -, p -, and s - ) and are bonded to a central carbon atom or skeleton are called functional groups. there are six prominent functional groups that can be found in organisms : amino group, carboxyl group, carbonyl group, hydroxyl group, phosphate group, and sulfhydryl group. in 1953, the miller – urey experiment showed that organic compounds could be synthesized abiotically within a closed system mimicking the conditions of early earth, thus suggesting that complex organic molecules could have arisen spontaneously in early earth ( see abiogenesis ). = = = macromolecules = = = macromolecules are large molecules made up of smaller subunits or monomers. monomers include sugars, amino acids, and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids are polymers of nucleotides. their function is to store, transmit, and express hereditary information. = = cells = = cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, and that all cells arise from preexisting cells through cell division functionalobjects. h allows the c + + programmer performing common mathematical calculations to use a more symbolic syntax rather than an algorithmic syntax. this is not as ambitious as a symbolic manipulation program such as mathematica ; it is more like having the ability to drop a very simple mathematica statement into a c + + program. to dye denim and the artist ' s pigments gamboge and rose madder. sugar, starch, cotton, linen, hemp, some types of rope, wood and particle boards, papyrus and paper, vegetable oils, wax, and natural rubber are examples of commercially important materials made from plant tissues or their secondary products. charcoal, a pure form of carbon made by pyrolysis of wood, has a long history as a metal - smelting fuel, as a filter material and adsorbent and as an artist ' s material and is one of the three ingredients of gunpowder. cellulose, the world ' s most abundant organic polymer, can be converted into energy, fuels, materials and chemical feedstock. products made from cellulose include rayon and cellophane, wallpaper paste, biobutanol and gun cotton. sugarcane, rapeseed and soy are some of the plants with a highly fermentable sugar or oil content that are used as sources of biofuels, important alternatives to fossil fuels, such as biodiesel. sweetgrass was used by native americans to ward off bugs like mosquitoes. these bug repelling properties of sweetgrass were later found by the american chemical society in the molecules phytol and coumarin. = = plant ecology = = plant ecology is the science of the functional relationships between plants and their habitats – the environments where they complete their life cycles. plant ecologists study the composition of local and regional floras, their biodiversity, genetic diversity and fitness, the adaptation of plants to their environment, and their competitive or mutualistic interactions with other species. some ecologists even rely on empirical data from indigenous people that is gathered by ethnobotanists. this information can relay a great deal of information on how the land once was thousands of years ago and how it has changed over that time. the goals of plant ecology are to understand the causes of their distribution patterns, productivity, environmental impact, evolution, and responses to environmental change. plants depend on certain edaphic ( soil ) and climatic factors in their environment but can modify these factors too. for example, they can change their environment ' s albedo, increase runoff interception, stabilise mineral soils and develop their organic content, and affect local temperature. plants compete with other organisms in their ecosystem for resources. they interact with their neighbours at a variety of spatial scales in groups, populations and communities that collectively constitute vegetation. regions with characteristic vegetation types and dominant plants as well as similar abiot applications continue to expand as researchers develop new kinds of ceramics to serve different purposes. zirconium dioxide ceramics are used in the manufacture of knives. the blade of the ceramic knife will stay sharp for much longer than that of a steel knife, although it is more brittle and can be snapped by dropping it on a hard surface. ceramics such as alumina, boron carbide and silicon carbide have been used in bulletproof vests to repel small arms rifle fire. such plates are known commonly as ballistic plates. similar material is used to protect cockpits of some military aircraft, because of the low weight of the material. silicon nitride parts are used in ceramic ball bearings. their higher hardness means that they are much less susceptible to wear and can offer more than triple lifetimes. they also deform less under load meaning they have less contact with the bearing retainer walls and can roll faster. in very high speed applications, heat from friction during rolling can cause problems for metal bearings ; problems which are reduced by the use of ceramics. ceramics are also more chemically resistant and can be used in wet environments where steel bearings would rust. the major drawback to using ceramics is a significantly higher cost. in many cases their electrically insulating properties may also be valuable in bearings. in the early 1980s, toyota researched production of an adiabatic ceramic engine which can run at a temperature of over 6000 °f ( 3300 °c ). ceramic engines do not require a cooling system and hence allow a major weight reduction and therefore greater fuel efficiency. fuel efficiency of the engine is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such Question: Hfcs are used as a replacement for what? A) nitrofluorocarbons B) cfcs C) pollutants D) gases	B) cfcs
Context: in space, can adversely affect the earth ' s environment. some hypergolic rocket propellants, such as hydrazine, are highly toxic prior to combustion, but decompose into less toxic compounds after burning. rockets using hydrocarbon fuels, such as kerosene, release carbon dioxide and soot in their exhaust. carbon dioxide emissions are insignificant compared to those from other sources ; on average, the united states consumed 803 million us gal ( 3. 0 million m3 ) of liquid fuels per day in 2014, while a single falcon 9 rocket first stage burns around 25, 000 us gallons ( 95 m3 ) of kerosene fuel per launch. even if a falcon 9 were launched every single day, it would only represent 0. 006 % of liquid fuel consumption ( and carbon dioxide emissions ) for that day. additionally, the exhaust from lox - and lh2 - fueled engines, like the ssme, is almost entirely water vapor. nasa addressed environmental concerns with its canceled constellation program in accordance with the national environmental policy act in 2011. in contrast, ion engines use harmless noble gases like xenon for propulsion. an example of nasa ' s environmental efforts is the nasa sustainability base. additionally, the exploration sciences building was awarded the leed gold rating in 2010. on may 8, 2003, the environmental protection agency recognized nasa as the first federal agency to directly use landfill gas to produce energy at one of its facilities — the goddard space flight center, greenbelt, maryland. in 2018, nasa along with other companies including sensor coating systems, pratt & whitney, monitor coating and utrc launched the project caution ( coatings for ultra high temperature detection ). this project aims to enhance the temperature range of the thermal history coating up to 1, 500 °c ( 2, 730 °f ) and beyond. the final goal of this project is improving the safety of jet engines as well as increasing efficiency and reducing co2 emissions. = = = climate change = = = nasa also researches and publishes on climate change. its statements concur with the global scientific consensus that the climate is warming. bob walker, who has advised former us president donald trump on space issues, has advocated that nasa should focus on space exploration and that its climate study operations should be transferred to other agencies such as noaa. former nasa atmospheric scientist j. marshall shepherd countered that earth science study was built into nasa ' s mission at its creation in the 1958 national aeronautics and space act. nasa won the 2020 webby people ' s voice award for green in the category the transition of our energy system to renewable energies is necessary in order not to heat up the climate any further and to achieve climate neutrality. the use of wind energy plays an important role in this transition in germany. but how much wind energy can be used and what are the possible consequences for the atmosphere if more and more wind energy is used? higher concentrations of atmospheric nitrous oxide ( n2o ) are expected to slightly warm earth ' s surface because of increases in radiative forcing. radiative forcing is the difference in the net upward thermal radiation flux from the earth through a transparent atmosphere and radiation through an otherwise identical atmosphere with greenhouse gases. radiative forcing, normally measured in w / m ^ 2, depends on latitude, longitude and altitude, but it is often quoted for the tropopause, about 11 km of altitude for temperate latitudes, or for the top of the atmosphere at around 90 km. for current concentrations of greenhouse gases, the radiative forcing per added n2o molecule is about 230 times larger than the forcing per added carbon dioxide ( co2 ) molecule. this is due to the heavy saturation of the absorption band of the relatively abundant greenhouse gas, co2, compared to the much smaller saturation of the absorption bands of the trace greenhouse gas n2o. but the rate of increase of co2 molecules, about 2. 5 ppm / year ( ppm = part per million by mole ), is about 3000 times larger than the rate of increase of n2o molecules, which has held steady at around 0. 00085 ppm / year since 1985. so, the contribution of nitrous oxide to the annual increase in forcing is 230 / 3000 or about 1 / 13 that of co2. if the main greenhouse gases, co2, ch4 and n2o have contributed about 0. 1 c / decade of the warming observed over the past few decades, this would correspond to about 0. 00064 k per year or 0. 064 k per century of warming from n2o. proposals to place harsh restrictions on nitrous oxide emissions because of warming fears are not justified by these facts. restrictions would cause serious harm ; for example, by jeopardizing world food supplies. pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, notably by richard roberts and joseph whitworth. the development of interchangeable parts through what is now called the american system of manufacturing began in the firearms industry at the u. s. federal arsenals in the early 19th century, and became widely used by the end of the century. until the enlightenment era, little progress was made in water supply and sanitation and the engineering skills of the romans were largely neglected throughout europe. the first documented use of sand filters to purify the water supply dates to 1804, when the owner of a bleachery in paisley, scotland, john gibb, installed an experimental filter, selling his unwanted surplus to the public. the first treated public water supply in the world was installed by engineer james simpson for the chelsea waterworks company in london in 1829. the first screw - down water tap was patented in 1845 by guest and chrimes, a brass foundry in rotherham. the practice of water treatment soon became mainstream, ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, notably by richard roberts and joseph whitworth. the development of interchangeable parts through what is now called the american system of manufacturing began in the firearms industry at the u. s. federal arsenals in the early 19th century, and became widely used by the end of the century. until the enlightenment era, little progress was made in water supply and sanitation and the engineering skills of the romans were largely neglected throughout europe. the first documented use of sand filters to purify the water supply dates to 1804, when the owner of a bleachery in paisley, scotland, john gibb, installed an experimental filter, selling his unwanted surplus to the public. the first treated public water supply in the world was installed by engineer james simpson for the chelsea waterworks company in london in 1829. the first screw - down water tap was patented in 1845 by guest and chrimes, a brass foundry in rotherham. the practice of water treatment soon became mainstream, and the virtues of the system were made starkly apparent after the investigations of the physician john snow during the 1854 broad street cholera outbreak demonstrated the role of the water supply in spreading the cholera epidemic. = = = second industrial revolution ( 1860s – 1914 ) = = = the 19th century saw astonishing developments in transportation, construction, enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest layer. in all, the atmosphere is made up of about 78. 0 % nitrogen, 20. 9 % oxygen, and 0. 92 % argon, and small amounts of other gases including co2 and water vapor. water vapor and co2 cause the earth ' s atmosphere to catch and hold the sun ' s energy through the greenhouse effect. this makes earth ' s surface warm enough for liquid water and life. in addition to trapping heat, the atmosphere also protects living organisms by shielding the earth ' s surface from cosmic rays. the magnetic field — created by the internal motions of the core — produces the magnetosphere which protects earth ' s atmosphere from the solar wind. as the earth is 4. 5 billion years old, it would have lost its atmosphere by now if there were no protective magnetosphere. = = earth ' s magnetic field = = = = hydrology = = hydrology is the study of the hydrosphere and the movement of water on earth. it emphasizes the study of how humans use and interact with freshwater supplies. study of water ' s movement is closely related to geomorphology and other branches of earth science. applied hydrology involves engineering to maintain aquatic environments and distribute water supplies. subdisciplines of hydrology include oceanography, hydrogeology, ecohydrology, and glaciology. oceanography is the study of oceans. hydrogeology is the study of groundwater. it includes the mapping of groundwater supplies and the analysis of groundwater contaminants. applied hydrogeology seeks to prevent contamination of groundwater and mineral springs and make it available as drinking water. the earliest exploitation of groundwater resources dates back to 3000 bc, and hydrogeology as a science was developed by hydrologists beginning in the 17th century. ecohydrology is the study of ecological systems in the hydrosphere. it can be divided into the physical study of aquatic ecosystems and the vehicle crashes. fuel economy / emissions : fuel economy is the measured fuel efficiency of the vehicle in miles per gallon or kilometers per liter. emissions - testing covers the measurement of vehicle emissions, including hydrocarbons, nitrogen oxides ( nox ), carbon monoxide ( co ), carbon dioxide ( co2 ), and evaporative emissions. nvh engineering ( noise, vibration, and harshness ) : nvh involves customer feedback ( both tactile [ felt ] and audible [ heard ] ) concerning a vehicle. while sound can be interpreted as a rattle, squeal, or hot, a tactile response can be seat vibration or a buzz in the steering wheel. this feedback is generated by components either rubbing, vibrating, or rotating. nvh response can be classified in various ways : powertrain nvh, road noise, wind noise, component noise, and squeak and rattle. note, there are both good and bad nvh qualities. the nvh engineer works to either eliminate bad nvh or change the " bad nvh " to good ( i. e., exhaust tones ). vehicle electronics : automotive electronics is an increasingly important aspect of automotive engineering. modern vehicles employ dozens of electronic systems. these systems are responsible for operational controls such as the throttle, brake and steering controls ; as well as many comfort - and - convenience systems such as the hvac, infotainment, and lighting systems. it would not be possible for automobiles to meet modern safety and fuel - economy requirements without electronic controls. performance : performance is a measurable and testable value of a vehicle ' s ability to perform in various conditions. performance can be considered in a wide variety of tasks, but it generally considers how quickly a car can accelerate ( e. g. standing start 1 / 4 mile elapsed time, 0 – 60 mph, etc. ), its top speed, how short and quickly a car can come to a complete stop from a set speed ( e. g. 70 - 0 mph ), how much g - force a car can generate without losing grip, recorded lap - times, cornering speed, brake fade, etc. performance can also reflect the amount of control in inclement weather ( snow, ice, rain ). shift quality : shift quality is the driver ' s perception of the vehicle to an automatic transmission shift event. this is influenced by the powertrain ( internal combustion engine, transmission ), and the vehicle ( driveline, suspension, engine and power industrial applications. this branch of biotechnology is the most used for the industries of refining and combustion principally on the production of bio - oils with photosynthetic micro - algae. green biotechnology is biotechnology applied to agricultural processes. an example would be the selection and domestication of plants via micropropagation. another example is the designing of transgenic plants to grow under specific environments in the presence ( or absence ) of chemicals. one hope is that green biotechnology might produce more environmentally friendly solutions than traditional industrial agriculture. an example of this is the engineering of a plant to express a pesticide, thereby ending the need of external application of pesticides. an example of this would be bt corn. whether or not green biotechnology products such as this are ultimately more environmentally friendly is a topic of considerable debate. it is commonly considered as the next phase of green revolution, which can be seen as a platform to eradicate world hunger by using technologies which enable the production of more fertile and resistant, towards biotic and abiotic stress, plants and ensures application of environmentally friendly fertilizers and the use of biopesticides, it is mainly focused on the development of agriculture. on the other hand, some of the uses of green biotechnology involve microorganisms to clean and reduce waste. red biotechnology is the use of biotechnology in the medical and pharmaceutical industries, and health preservation. this branch involves the production of vaccines and antibiotics, regenerative therapies, creation of artificial organs and new diagnostics of diseases. as well as the development of hormones, stem cells, antibodies, sirna and diagnostic tests. white biotechnology, also known as industrial biotechnology, is biotechnology applied to industrial processes. an example is the designing of an organism to produce a useful chemical. another example is the using of enzymes as industrial catalysts to either produce valuable chemicals or destroy hazardous / polluting chemicals. white biotechnology tends to consume less in resources than traditional processes used to produce industrial goods. yellow biotechnology refers to the use of biotechnology in food production ( food industry ), for example in making wine ( winemaking ), cheese ( cheesemaking ), and beer ( brewing ) by fermentation. it has also been used to refer to biotechnology applied to insects. this includes biotechnology - based approaches for the control of harmful insects, the characterisation and utilisation of active ingredients or genes of insects for research, or application in agriculture and medicine and various other approaches. gray biotechnology is dedicated to environmental applications, and focused on the maintenance of biodiversity and the remotion of poll nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of if the hazard rate $ \ frac { f ' ( x ) } { 1 - f ( x ) } $ is increasing ( in $ x $ ), then $ \ mathbb e \, ( x _ { n : n } - x _ { n - 1 : n } ) $ is decreasing ( in $ n $ ), and moreover, completely monotone. Question: What has the burning of fossil fuels increased in the atmosphere? A) carbon dioxide B) ozone C) temperature D) oxygen	A) carbon dioxide
Context: their mechanical properties. = = tissue culture = = in many cases, creation of functional tissues and biological structures in vitro requires extensive culturing to promote survival, growth and inducement of functionality. in general, the basic requirements of cells must be maintained in culture, which include oxygen, ph, humidity, temperature, nutrients and osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can , there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support as well as being involved in reproduction and breakdown of plant seeds. eukaryotic cells also have cytoskeleton that is made up of microtubules, intermediate filaments, and microfilaments, all of which provide support for the cell and are involved in the movement of the cell and its organelles. in terms of their structural composition, the microtubules are made up of tubulin ( e. g., α - tubulin and β - tubulin ) whereas intermediate filaments are made up of fibrous proteins. microfilaments are made up of actin molecules that interact with other strands of proteins. = = = metabolism = = = all cells require energy to sustain cellular processes. metabolism is the set of chemical reactions in an organism. the three main purposes of metabolism are : the conversion of food to energy to run cellular processes ; the conversion of food / fuel to monomer building blocks ; and the elimination of metabolic wastes. these enzyme - catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. metabolic reactions may be categorized as catabolic — the breaking down of compounds ( for example, the breaking down of glucose to pyruvate by cellular respiration ) ; or anabolic — the building up ( synthesis ) of compounds ( such as proteins, carbohydrates, lipids, and nucleic acids ). usually, catabolism releases energy, and anabolism consumes energy. the chemical reactions of metabolism are organized into metabolic pathways, in which the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support as well as being involved in reproduction and breakdown of plant seeds. eukaryotic cells also have cytoskeleton that is made up of microtubules, intermediate filaments, and microfilaments, all of which provide support for the cell and are involved in the movement of the cell and its organelles. in terms of their structural composition, the microtubules are made up of tubulin ( e. g., α - tubulin and β - tubulin ) whereas intermediate filaments are made up of fibrous proteins. microfilaments are made up of actin molecules that interact with other strands of proteins. = = = metabolism = = = all cells require energy to sustain cellular processes. metabolism is the set of chemical reactions in an organism. the three main purposes of metabolism are : the conversion of food to energy to run cellular processes ; the conversion of food / fuel to monomer building blocks ; and the elimination of metabolic wastes. these enzyme - catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. metabolic reactions may be categorized as catabolic — the breaking down of compounds ( for example, the breaking down of glucose to pyruvate by cellular respiration ) ; or anabolic — the building up ( synthesis ) of compounds ( such as proteins, carbohydrates, lipids, and nucleic acids ). usually, catabolism releases energy, and anabolism consumes energy. the chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme. enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. enzymes act as catalysts — they allow a young plant cells, and electroporation, which involves using an electric shock to make the cell membrane permeable to plasmid dna. as only a single cell is transformed with genetic material, the organism must be regenerated from that single cell. in plants this is accomplished through the use of tissue culture. in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes of homologous recombination and nonhomologous end - joining. there are four families of engineered nucleases : meganucleases, zinc finger nucleases, transcription activator - like effector nucleases ( talens ), and the cas9 - guiderna system ( adapted from crispr ). talen and crispr are the two most commonly used and each has its own advantages. talens have greater target specificity, while crispr is easier to design and more efficient. in addition to enhancing gene targeting, engineered nucleases can be used to introduce mutations shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell, there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support as well as being involved in reproduction and breakdown of plant seeds. eukaryotic cells also have cytoskeleton that is made up of microtubules, intermediate filaments, and microfilaments, all of which provide support for the cell and are involved in the movement of the cell and its organelles. in terms of their structural composition, the microtubules are made up of tubulin ( e. g., α - tubulin and β - tubulin ) whereas intermediate filaments are made up of fibrous proteins. microfilaments are made up of actin molecules that interact with other strands of proteins. = = = metabolism = = = all cells require energy to sustain cellular processes. metabolism is the set of chemical reactions in an organism. the three main purposes of metabolism are : the conversion of food to energy to run cellular processes ; the conversion of food / fuel to monomer building blocks ; and the elimination of metabolic wastes. these enzyme - catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. metabolic reactions may be categorized as catabolic — the breaking down of compounds ( for example, the breaking down of glucose to pyruvate by cellular respiration ##s ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up the muck tube. the pressurized air flow must be constant to ensure regular air changes for the workers and prevent excessive inflow of mud or water at the base of the caisson. when the caisson hits bedrock, the sandhogs exit through the airlock and fill the box with concrete, forming a solid foundation pier. a pneumatic ( compressed - air ) caisson has the advantage of providing dry working conditions, which is better for placing concrete. it is also well suited for foundations for which other methods might cause settlement of adjacent structures. construction workers who leave the pressurized environment of the caisson must decompress at a rate that allows symptom - free release of inert gases dissolved in the body tissues if they are to avoid decompression sickness, a condition first identified in caisson workers, and originally named " caisson disease " in recognition of the occupational hazard. construction of the brooklyn bridge, which was built with the help of pressurised caissons, resulted in numerous workers being either killed or permanently injured by caisson disease during its construction. barotrauma of the ears, sinus cavities and lungs and dysbaric osteonecrosis are other risks. = = other uses = = caissons have also been used in the installation of hydraulic elevators where a single - stage ram is installed below the ground level. caissons, codenamed phoenix, were an integral part of the mulberry harbours used during the world war ii allied invasion of normandy. = = other meanings = = boat lift caissons : the word caisson is also used as a synonym for the moving trough part of caisson locks, canal lifts and inclines in which boats and ships rest while being lifted from one canal elevation to another ; the water is retained on the inside of the caisson, or excluded from the caisson there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively in future clinical stem cell therapies. mc2 biotek has also developed a bioreactor known as prototissue that uses gas exchange to maintain high oxygen levels within the cell chamber ; improving upon previous bioreactors, since the higher oxygen levels help the cell grow and undergo normal cell respiration. active areas of research on bioreactors includes increasing production scale and refining the physiological environment, both of which could improve the efficiency and efficacy of bioreactors in research or clinical use. bioreactors are currently used to study, among other things, cell and tissue level therapies, cell and tissue response to specific physiological environment changes, and development of disease and injury. = = = long fiber generation = = = in 2013, a group from the university of tokyo developed cell laden fibers up to a meter in length and on the order of 100 μm in size. these fibers were created using a microfluidic device that forms a animal cells using microinjection, where it can be injected through the cell ' s nuclear envelope directly into the nucleus, or through the use of viral vectors. plant genomes can be engineered by physical methods or by use of agrobacterium for the delivery of sequences hosted in t - dna binary vectors. in plants the dna is often inserted using agrobacterium - mediated transformation, taking advantage of the agrobacteriums t - dna sequence that allows natural insertion of genetic material into plant cells. other methods include biolistics, where particles of gold or tungsten are coated with dna and then shot into young plant cells, and electroporation, which involves using an electric shock to make the cell membrane permeable to plasmid dna. as only a single cell is transformed with genetic material, the organism must be regenerated from that single cell. in plants this is accomplished through the use of tissue culture. in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up the muck tube. the pressurized air flow must be constant to ensure regular air changes for the workers and prevent excessive inflow of mud or water at the base of the caisson. when the caisson hits bedrock, the sandhogs exit through the airlock and fill the box with concrete, forming a solid foundation pier. a pneumatic ( compressed - air ) caisson has the advantage of providing dry working conditions, which is better for placing concrete. it is also well suited for foundations for which other methods might cause settlement of adjacent structures. construction workers who leave the pressurized environment of the caisson must decompress at a rate that allows symptom - free release of inert gases dissolved in the body tissues if they are to avoid decompression sickness, a condition first identified in caisson workers, and originally named " caisson disease " in recognition of the occupational hazard. construction of the brooklyn bridge, which was built with the help of pressurised caissons, resulted in numerous workers being either killed or permanently injured by caisson disease during its construction. barotrauma of the ears, sinus cavities and lungs and dysbaric osteonecrosis are other risks. = = other uses = = caissons have also been used in the installation of hydraulic elevators where a single - stage ram is installed below the ground level. caissons, codenamed phoenix, were an integral part of the mulberry harbours used during the world war ii allied invasion of normandy. = = other meanings = = boat lift caissons : the word caisson is also used as a synonym for the moving trough part of caisson locks, canal lifts and inclines in which boats and ships rest while being lifted from one canal elevation to another ; the water is retained on the inside of the caisson, or excluded from the caisson, according to the respective operating principle. structural caissons : caisson is also sometimes used as a colloquial term for a reinforced concrete structure formed by pouring into a hollow cylindrical form, typically by placing a caisson form below grade in an open excavation and pouring once backfill is complete, or by allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively in future clinical stem cell therapies. mc2 biotek has also developed a bioreactor known as prototissue that uses gas exchange to maintain high oxygen levels within the cell chamber ; improving upon previous bioreactors, since the higher oxygen levels help the cell grow and undergo normal cell respiration. active areas of research on bioreactors includes increasing production scale and refining the physiological environment, both of which could improve the efficiency and efficacy of bioreactors in research or clinical use. bioreactors are currently used to study, among other things, cell and tissue level therapies, cell and tissue response to specific physiological Question: In humans, the sperm cell is the only cell with what structure that enables motility? A) flagella B) False Cell C) sporangia D) eukaryotic	A) flagella
Context: time - dependent distribution of the global extinction of megafauna is compared with the growth of human population. there is no correlation between the two processes. furthermore, the size of human population and its growth rate were far too small to have any significant impact on the environment and on the life of megafauna. , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became . microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea ##rozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokar when fast radio burst ( frb ) waves propagate through the local ( < 1 pc ) environment of the frb source, electrons in the plasma undergo large - amplitude oscillations. the finite - amplitude effects cause the effective plasma frequency and cyclotron frequency to be dependent on the wave strength. the dispersion measure and rotation measure should therefore vary slightly from burst to burst for a repeating source, depending on the luminosity and frequency of the individual burst. furthermore, free - free absorption of strong waves is suppressed due to the accelerated electrons ' reduced energy exchange in coulomb collisions. this allows bright low - frequency bursts to propagate through an environment that would be optically thick to low - amplitude waves. given a large sample of bursts from a repeating source, it would be possible to use the deficit of low - frequency and low - luminosity bursts to infer the emission measure of the local intervening plasma and its distance from the source. information about the local environment will shed light on the nature of frb sources. time interval between the incident and scattered photon in raman effect and absorption of photon and emission of electron in photoelectric effect has not been determined till now. this is because there is no such high level instrument discovered till now to detect time interval to such a small level. but this can be calculated theoretically by applying a basic principle of physics like impulse is equal to the change in momentum. considering the collision between electron and photon as perfect inelastic collision in photoelectric effect, elastic and inelastic collision in raman effect and elastic collision in plane mirror reflection and the interaction between electron and photon as strong gravitational interaction we calculate the required time interval. during these phenomena there is lattice vibration which can be quantized as phonon particles. rolling out 5g services across the us. 5g started being deployed at the beginning of 2020 and has been growing ever since. according to the gsm association, by 2025, approximately 1. 7 billion subscribers will have a subscription with 5g service. 5g wireless signals are transmitted through large numbers of small cell stations located in places like light poles or building roofs. in the past, 4g networking had to rely on large cell towers in order to transmit signals over large distances. with the introduction of 5g networking, it is imperative that small cell stations are used because the mm wave spectrum, which is the specific type of band used in 5g services, strictly travels over short distances. if the distances between cell stations were longer, signals may suffer from interference from inclimate weather, or other objects such as houses, buildings, trees, and much more. in 5g networking, there are 3 main kinds of 5g : low - band, mid - band, and high - band. low - band frequencies operate below 2 ghz, mid - band frequencies operate between 2 – 10 ghz, and high - band frequencies operate between 20 and 100 ghz. verizon have seen outrageous numbers on their high - band 5g service, which they deem " ultraband ", which hit speeds of over 3 gbit / s. the main advantage of 5g networks is that the data transmission rate is much higher than the previous cellular network, up to 10 gbit / s, which is faster than the current wired internet and 100 times faster than the previous 4g lte cellular network. another advantage is lower network latency ( faster response time ), less than 1 millisecond, and 4g is 30 - 70 milliseconds. the peak rate needs to reach the gbit / s standard to meet the high data volume of high - definition video, virtual reality and so on. the air interface delay level needs to be around 1ms, which meets real - time applications such as autonomous driving and telemedicine. large network capacity, providing the connection capacity of 100 billion devices to meet iot communication. the spectrum efficiency is 10 times higher than lte. with continuous wide area coverage and high mobility, the user experience rate reaches 100 mbit / s. the flow density and the number of connections are greatly increased. since 5g is a relatively new type of service, only phones which are newly released or are upcoming can support 5g service. some of these phones include the iphone 12 / 13 ; select 0. 1 and 100 nm in each spatial dimension. the terms nanoparticles and ultrafine particles ( ufp ) often are used synonymously although ufp can reach into the micrometre range. the term ' nanostructure ' is often used, when referring to magnetic technology. nanoscale structure in biology is often called ultrastructure. = = = = microstructure = = = = microstructure is defined as the structure of a prepared surface or thin foil of material as revealed by a microscope above 25× magnification. it deals with objects from 100 nm to a few cm. the microstructure of a material ( which can be broadly classified into metallic, polymeric, ceramic and composite ) can strongly influence physical properties such as strength, toughness, ductility, hardness, corrosion resistance, high / low temperature behavior, wear resistance, and so on. most of the traditional materials ( such as metals and ceramics ) are microstructured. the manufacture of a perfect crystal of a material is physically impossible. for example, any crystalline material will contain defects such as precipitates, grain boundaries ( hall – petch relationship ), vacancies, interstitial atoms or substitutional atoms. the microstructure of materials reveals these larger defects and advances in simulation have allowed an increased understanding of how defects can be used to enhance material properties. = = = = macrostructure = = = = macrostructure is the appearance of a material in the scale millimeters to meters, it is the structure of the material as seen with the naked eye. = = = properties = = = materials exhibit myriad properties, including the following. mechanical properties, see strength of materials chemical properties, see chemistry electrical properties, see electricity thermal properties, see thermodynamics optical properties, see optics and photonics magnetic properties, see magnetism the properties of a material determine its usability and hence its engineering application. = = = processing = = = synthesis and processing involves the creation of a material with the desired micro - nanostructure. a material cannot be used in industry if no economically viable production method for it has been developed. therefore, developing processing methods for materials that are reasonably effective and cost - efficient is vital to the field of materials science. different materials require different processing or synthesis methods. for example, the processing of metals has historically defined eras such as the bronze age and iron age and is studied under the branch of materials science named physical metallurgy. Question: Dispersal occurs only on what time scale? A) conventional B) regular C) evolutionary D) developmental	C) evolutionary
Context: you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), , followed by a medical interview and a physical examination. basic diagnostic medical devices ( e. g., stethoscope, tongue depressor ) are typically used. after examining for signs and interviewing for symptoms, the doctor may order medical tests ( e. g., blood tests ), take a biopsy, or prescribe pharmaceutical drugs or other therapies. differential diagnosis methods help to rule out conditions based on the information provided. during the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. the medical encounter is then documented in the medical record, which is a legal document in many jurisdictions. follow - ups may be shorter but follow the same general procedure, and specialists follow a similar process. the diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue. the components of the medical interview and encounter are : chief complaint ( cc ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history of a point on the object, including whole - body translations and rotations ( rigid transformations ). deformation are changes in the relative position between internals points on the object, excluding rigid transformations, causing the body to change shape or size. strain is the relative internal deformation, the dimensionless change in shape of an infinitesimal cube of material relative to a reference configuration. mechanical strains are caused by mechanical stress, see stress - strain curve. the relationship between stress and strain is generally linear and reversible up until the yield point and the deformation is elastic. elasticity in materials occurs when applied stress does not surpass the energy required to break molecular bonds, allowing the material to deform reversibly and return to its original shape once the stress is removed. the linear relationship for a material is known as young ' s modulus. above the yield point, some degree of permanent distortion remains after unloading and is termed plastic deformation. the determination of the stress and strain throughout a solid object is given by the field of strength of materials and for a structure by structural analysis. in the above figure, it can be seen that the compressive loading ( indicated by the arrow ) has caused deformation in the cylinder so that the original shape ( dashed lines ) has changed ( deformed ) into one with bulging sides. the sides bulge because the material, although strong enough to not crack or otherwise fail, is not strong enough to support the load without change. as a result, the material is forced out laterally. internal forces ( in this case at right angles to the deformation ) resist the applied load. = = types of deformation = = depending on the type of material, size and geometry of the object, and the forces applied, various types of deformation may result. the image to the right shows the engineering stress vs. strain diagram for a typical ductile material such as steel. different deformation modes may occur under different conditions, as can be depicted using a deformation mechanism map. permanent deformation is irreversible ; the deformation stays even after removal of the applied forces, while the temporary deformation is recoverable as it disappears after the removal of applied forces. temporary deformation is also called elastic deformation, while the permanent deformation is called plastic deformation. = = = elastic deformation = = = the study of temporary or elastic deformation in the case of engineering strain is applied to materials used in mechanical and structural engineering, such as concrete and steel, which are subjected to very small deformations. engineering strain is modeled by infinitesimal strain theory, also called and the creation of genetically modified crops. = = = epigenetics = = = epigenetics is the study of heritable changes in gene function that cannot be explained by changes in the underlying dna sequence but cause the organism ' s genes to behave ( or " express themselves " ) differently. one example of epigenetic change is the marking of the genes by dna methylation which determines whether they will be expressed or not. gene expression can also be controlled by repressor proteins that attach to silencer regions of the dna and prevent that region of the dna code from being expressed. epigenetic marks may be added or removed from the dna during programmed stages of development of the plant, and are responsible, for example, for the differences between anthers, petals and normal leaves, despite the fact that they all have the same underlying genetic code. epigenetic changes may be temporary or may remain through successive cell divisions for the remainder of the cell ' s life. some epigenetic changes have been shown to be heritable, while others are reset in the germ cells. epigenetic changes in eukaryotic biology serve to regulate the process of cellular differentiation. during morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo, which in turn become fully differentiated cells. a single fertilised egg cell, the zygote, gives rise to the many different plant cell types including parenchyma, xylem vessel elements, phloem sieve tubes, guard cells of the epidermis, etc. as it continues to divide. the process results from the epigenetic activation of some genes and inhibition of others. unlike animals, many plant cells, particularly those of the parenchyma, do not terminally differentiate, remaining totipotent with the ability to give rise to a new individual plant. exceptions include highly lignified cells, the sclerenchyma and xylem which are dead at maturity, and the phloem sieve tubes which lack nuclei. while plants use many of the same epigenetic mechanisms as animals, such as chromatin remodelling, an alternative hypothesis is that plants set their gene expression patterns using positional information from the environment and surrounding cells to determine their developmental fate. epigenetic changes can lead to paramutations, which do not follow the mendelian heritage rules. these epigenetic marks are carried from one generation to the next, a legal document in many jurisdictions. follow - ups may be shorter but follow the same general procedure, and specialists follow a similar process. the diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue. the components of the medical interview and encounter are : chief complaint ( cc ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on , social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary the rapidly developing research field of organic analogue sensors aims to replace traditional semiconductors with naturally occurring materials. photosensors, or photodetectors, change their electrical properties in response to the light levels they are exposed to. organic photosensors can be functionalised to respond to specific wavelengths, from ultra - violet to red light. performing cyclic voltammetry on fungal mycelium and fruiting bodies under different lighting conditions shows no appreciable response to changes in lighting condition. however, functionalising the specimen using pedot : pss yields in a photosensor that produces large, instantaneous current spikes when the light conditions change. future works would look at interfacing this organic photosensor with an appropriate digital back - end for interpreting and processing the response. from the oil of jasminum grandiflorum which regulates wound responses in plants by unblocking the expression of genes required in the systemic acquired resistance response to pathogen attack. in addition to being the primary energy source for plants, light functions as a signalling device, providing information to the plant, such as how much sunlight the plant receives each day. this can result in adaptive changes in a process known as photomorphogenesis. phytochromes are the photoreceptors in a plant that are sensitive to light. = = plant anatomy and morphology = = plant anatomy is the study of the structure of plant cells and tissues, whereas plant morphology is the study of their external form. all plants are multicellular eukaryotes, their dna stored in nuclei. the characteristic features of plant cells that distinguish them from those of animals and fungi include a primary cell wall composed of the polysaccharides cellulose, hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable Question: What type of feedback intensifies a change in the body’s physiological condition rather than reversing it? A) negative feedback B) positive feedback C) neutral feedback D) susceptible feedback	B) positive feedback
Context: ##lling, pipe jacking and other operations. a caisson is sunk by self - weight, concrete or water ballast placed on top, or by hydraulic jacks. the leading edge ( or cutting shoe ) of the caisson is sloped out at a sharp angle to aid sinking in a vertical manner ; it is usually made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caissons ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called oil umbrella ) ; for calculating the time of death ( allowing for weather and insect activity ) ; described how to wash and examine the dead body to ascertain the reason for death. at that time the book had described methods for distinguishing between suicide and faked suicide. he wrote the book on forensics stating that all wounds or dead bodies should be examined, not avoided. the book became the first form of literature to help determine the cause of death. in one of song ci ' s accounts ( washing away of wrongs ), the case of a person murdered with a sickle was solved by an investigator who instructed each suspect to bring his sickle to one location. ( he realized it was a sickle by testing various blades on an animal carcass and comparing the wounds. ) flies, attracted by the smell of blood, eventually gathered on a single sickle. in light of this, the owner of that sickle confessed to the murder. the book also described how to distinguish between a drowning ( water in the lungs ) and strangulation ( broken neck cartilage ), and described evidence from examining corpses to determine if a death was caused by murder, suicide or accident. methods from around the world involved saliva and examination of the mouth and tongue to determine innocence or guilt, as a precursor to the polygraph test. in ancient india, some suspects were made to fill their mouths with dried rice and spit it back out. similarly, in ancient china, those accused of a crime would have rice powder placed in their mouths. in ancient middle - eastern cultures, the accused were made to lick hot metal rods briefly. it is thought that these tests had some validity since a guilty person would produce less saliva and thus have a drier mouth ; the accused would be considered guilty if rice was sticking to their mouths in abundance or if their tongues were severely burned due to lack of shielding from saliva. = = education and training = = initial glance, forensic intelligence may appear as a nascent facet of forensic science facilitated by advancements in information technologies such as computers, databases, and data - flow management software. however, a more profound examination reveals that forensic intelligence represents a genuine and emerging inclination among forensic practitioners to actively participate in investigative and policing strategies. in doing so, it elucidates existing practices within scientific literature, advocating for a paradigm shift from the prevailing conception of forensic science as a conglomerate of disciplines merely aiding the criminal justice system. instead, it urges a perspective that views forensic science as a discipline studying the informative potential of scientists look through telescopes, study images on electronic screens, record meter readings, and so on. generally, on a basic level, they can agree on what they see, e. g., the thermometer shows 37. 9 degrees c. but, if these scientists have different ideas about the theories that have been developed to explain these basic observations, they may disagree about what they are observing. for example, before albert einstein ' s general theory of relativity, observers would have likely interpreted an image of the einstein cross as five different objects in space. in light of that theory, however, astronomers will tell you that there are actually only two objects, one in the center and four different images of a second object around the sides. alternatively, if other scientists suspect that something is wrong with the telescope and only one object is actually being observed, they are operating under yet another theory. observations that cannot be separated from theoretical interpretation are said to be theory - laden. all observation involves both perception and cognition. that is, one does not make an observation passively, but rather is actively engaged in distinguishing the phenomenon being observed from surrounding sensory data. therefore, observations are affected by one ' s underlying understanding of the way in which the world functions, and that understanding may influence what is perceived, noticed, or deemed worthy of consideration. in this sense, it can be argued that all observation is theory - laden. = = = the purpose of science = = = should science aim to determine ultimate truth, or are there questions that science cannot answer? scientific realists claim that science aims at truth and that one ought to regard scientific theories as true, approximately true, or likely true. conversely, scientific anti - realists argue that science does not aim ( or at least does not succeed ) at truth, especially truth about unobservables like electrons or other universes. instrumentalists argue that scientific theories should only be evaluated on whether they are useful. in their view, whether theories are true or not is beside the point, because the purpose of science is to make predictions and enable effective technology. realists often point to the success of recent scientific theories as evidence for the truth ( or near truth ) of current theories. antirealists point to either the many false theories in the history of science, epistemic morals, the success of false modeling assumptions, or widely termed postmodern criticisms of objectivity as evidence against scientific realism. antirealists attempt to explain the success of scientific theories without reference to truth. some antirealists claim that scientific designates the relationship between two or more variables. conceptual definition : description of a concept by relating it to other concepts. operational definition : details in regards to defining the variables and how they will be measured / assessed in the study. gathering of data : consists of identifying a population and selecting samples, gathering information from or about these samples by using specific research instruments. the instruments used for data collection must be valid and reliable. analysis of data : involves breaking down the individual pieces of data to draw conclusions about it. data interpretation : this can be represented through tables, figures, and pictures, and then described in words. test, revising of hypothesis conclusion, reiteration if necessary a common misconception is that a hypothesis will be proven ( see, rather, null hypothesis ). generally, a hypothesis is used to make predictions that can be tested by observing the outcome of an experiment. if the outcome is inconsistent with the hypothesis, then the hypothesis is rejected ( see falsifiability ). however, if the outcome is consistent with the hypothesis, the experiment is said to support the hypothesis. this careful language is used because researchers recognize that alternative hypotheses may also be consistent with the observations. in this sense, a hypothesis can never be proven, but rather only supported by surviving rounds of scientific testing and, eventually, becoming widely thought of as true. a useful hypothesis allows prediction and within the accuracy of observation of the time, the prediction will be verified. as the accuracy of observation improves with time, the hypothesis may no longer provide an accurate prediction. in this case, a new hypothesis will arise to challenge the old, and to the extent that the new hypothesis makes more accurate predictions than the old, the new will supplant it. researchers can also use a null hypothesis, which states no relationship or difference between the independent or dependent variables. = = = research in the humanities = = = research in the humanities involves different methods such as for example hermeneutics and semiotics. humanities scholars usually do not search for the ultimate correct answer to a question, but instead, explore the issues and details that surround it. context is always important, and context can be social, historical, political, cultural, or ethnic. an example of research in the humanities is historical research, which is embodied in historical method. historians use primary sources and other evidence to systematically investigate a topic, and then to write histories in the form of accounts of the past. other studies aim to merely examine the occurrence of behaviours in societies and communities the gravitational poynting vector provides a mechanism for the transfer of gravitational energy to a system of falling objects. in the following we will show that the gravitational poynting vector together with the gravitational larmor theorem also provides a mechanism to explain how massive bodies acquire rotational kinetic energy when external mechanical forces are applied on them. river - beds ), but not for where there may be large obstructions in the ground. an open caisson that is used in soft grounds or high water tables, where open trench excavations are impractical, can also be used to install deep manholes, pump stations and reception / launch pits for microtunnelling, pipe jacking and other operations. a caisson is sunk by self - weight, concrete or water ballast placed on top, or by hydraulic jacks. the leading edge ( or cutting shoe ) of the caisson is sloped out at a sharp angle to aid sinking in a vertical manner ; it is usually made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caisson necessary and sufficient conditions for a term to apply to an object. for example : " a platonic solid is a convex, regular polyhedron in three - dimensional euclidean space. " an extensional definition instead lists all objects where the term applies. for example : " a platonic solid is one of the following : tetrahedron, cube, octahedron, dodecahedron, or icosahedron. " in logic, the extension of a predicate is the set of all objects for which the predicate is true. further, the logical principle of extensionality judges two objects to objects to be equal if they satisfy the same external properties. since, by the axiom, two sets are defined to be equal if they satisfy membership, sets are extentional. jose ferreiros credits richard dedekind for being the first to explicitly state the principle, although he does not assert it as a definition : it very frequently happens that different things a, b, c... considered for any reason under a common point of view, are collected together in the mind, and one then says that they form a system s ; one calls the things a, b, c... the elements of the system s, they are contained in s ; conversely, s consists of these elements. such a system s ( or a collection, a manifold, a totality ), as an object of our thought, is likewise a thing ; it is completely determined when, for every thing, it is determined whether it is an element of s or not. = = = background = = = around the turn of the 20th century, mathematics faced several paradoxes and counter - intuitive results. for example, russell ' s paradox showed a contradiction of naive set theory, it was shown that the parallel postulate cannot be proved, the existence of mathematical objects that cannot be computed or explicitly described, and the existence of theorems of arithmetic that cannot be proved with peano arithmetic. the result was a foundational crisis of mathematics. the resolution of this crisis involved the rise of a new mathematical discipline called mathematical logic, which studies formal logic within mathematics. subsequent discoveries in the 20th century then stabilized the foundations of mathematics into a coherent framework valid for all mathematics. this framework is based on a systematic use of axiomatic method and on set theory, specifically zermelo – fraenkel set theory, developed by ernst zermelo and abraham fraenkel. this set theory ( and set theory in general ) is now considered the most common foundation of mathematics so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : 42 – 48 confirmation bias is a form of cognitive bias. : 553 from the literature, astrology believers often tend to selectively remember those predictions that turned out to be true and do not remember those that turned out false. another, separate, form of confirmation bias also plays a role, where believers often fail to , the oxygen atom has a slight negative charge and the two hydrogen atoms have a slight positive charge. this polar property of water allows it to attract other water molecules via hydrogen bonds, which makes water cohesive. surface tension results from the cohesive force due to the attraction between molecules at the surface of the liquid. water is also adhesive as it is able to adhere to the surface of any polar or charged non - water molecules. water is denser as a liquid than it is as a solid ( or ice ). this unique property of water allows ice to float above liquid water such as ponds, lakes, and oceans, thereby insulating the liquid below from the cold air above. water has the capacity to absorb energy, giving it a higher specific heat capacity than other solvents such as ethanol. thus, a large amount of energy is needed to break the hydrogen bonds between water molecules to convert liquid water into water vapor. as a molecule, water is not completely stable as each water molecule continuously dissociates into hydrogen and hydroxyl ions before reforming into a water molecule again. in pure water, the number of hydrogen ions balances ( or equals ) the number of hydroxyl ions, resulting in a ph that is neutral. = = = organic compounds = = = organic compounds are molecules that contain carbon bonded to another element such as hydrogen. with the exception of water, nearly all the molecules that make up each organism contain carbon. carbon can form covalent bonds with up to four other atoms, enabling it to form diverse, large, and complex molecules. for example, a single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such as octane or ring - like structures such as glucose. the simplest form of an organic molecule is the hydrocarbon, which is a large family of organic compounds that are composed of hydrogen atoms bonded to a chain of carbon atoms. a hydrocarbon backbone can be substituted by other elements such as oxygen ( o ), hydrogen ( h ), phosphorus ( p ), and sulfur ( s ), which can change the chemical behavior of that compound. groups of atoms that contain these elements ( o -, h -, p -, and s - ) and are bonded to a central carbon atom or skeleton are called functional groups. there are six some topics which can be easily explained to undergraduate students are presented, with elementary derivations. for a more systematic treatment of heavy - quark physics, see the textbook by manohar and wise. Question: What law explains why some objects float and some sink. A) archimedes' law B) newton's law C) flanges ' law D) montenegrins ' law	A) archimedes' law
Context: einstein, when he began working on the general theory of relativity, believed that energy of any kind is the source of the gravitational field. therefore, the energy of gravity, like any energy, must be the source of the field. it was previously discovered that the energy - momentum tensor of the gravitational field is already contained in the ricci tensor. this hypothesis is used to construct a new equation of the gravitational field. the value of excess charge in the kernel of massive body ( and the opposite in sign excess charge at the surface ) caused by the influence of gravitational forces is determined. the gravitational poynting vector provides a mechanism for the transfer of gravitational energy to a system of falling objects. in the following we will show that the gravitational poynting vector together with the gravitational larmor theorem also provides a mechanism to explain how massive bodies acquire rotational kinetic energy when external mechanical forces are applied on them. so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : 42 – 48 confirmation bias is a form of cognitive bias. : 553 from the literature, astrology believers often tend to selectively remember those predictions that turned out to be true and do not remember those that turned out false. another, separate, form of confirmation bias also plays a role, where believers often fail to . this, he argued, would have been more persuasive and would have produced less controversy. the use of poetic imagery based on the concepts of the macrocosm and microcosm, " as above so below " to decide meaning such as edward w. james ' example of " mars above is red, so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : the united rest mass and charge of a particle correspond to the two forms of the same regularity of the unified nature of its ultimate structure. each of them contains the electric, weak, strong and the gravitational contributions. as a consequence, the force of an attraction among the two neutrinos and force of their repulsion must be defined from the point of view of any of the existing types of the actions. therefore, to understand the nature of the micro world interaction at the fundamental level, one must use the fact that each of the four types of well known forces includes both a kind of the newton and a kind of the coulomb components. the opinion has been spoken that the existence of the gravitational parts of the united rest mass and charge would imply the availability of such a fifth force which come forwards in the system as a unified whole. i have been asked to write brief, gentle introduction to the basic idea behind the field of " quantum gravity " in 1500 words or less. doing so appears to be almost as great a challenge as coming up with a consistent theory of quantum gravity. however, i will try. disclaimer : \ emph { the views expressed in this article are my own and do not represent the consensus of the quantum gravity community }. an essay on horndeski gravity, how it was formulated in the early 1970s and how it was ' re - discovered ' and widely adopted by cosmologists more than thirty years later. a suitable choice of the four components of the metric tensor which are at our discretion allows to represent geodesically also the non - gravitational motions. the project consists to determine, mathematically, the trajectory that will take an artificial satellite to fight against the air resistance. during our work, we had to consider that our satellite will crash to the surface of our planet. we started our study by understanding the system of forces that are acting between our satellite and the earth. in this work, we had to study the second law of newton by taking knowledge of the air friction, the speed of the satellite which helped us to find the equation that relates the trajectory of the satellite itself, its speed and the density of the air depending on the altitude. finally, we had to find a mathematic relation that links the density with the altitude and then we had to put it into our movement equation. in order to verify our model, we ' ll see what happens if we give a zero velocity to the satellite. Question: What is the force of gravity called? A) pressure B) mass C) weight D) scale	C) weight
Context: reflect radar waves back to the emitting radar is with orthogonal metal plates, forming a corner reflector consisting of either a dihedral ( two plates ) or a trihedral ( three orthogonal plates ). this configuration occurs in the tail of a conventional aircraft, where the vertical and horizontal components of the tail are set at right angles. stealth aircraft such as the f - 117 use a different arrangement, tilting the tail surfaces to reduce corner reflections formed between them. a more radical method is to omit the tail, as in the b - 2 spirit. the b - 2 ' s clean, low - drag flying wing configuration gives it exceptional range and reduces its radar profile. the flying wing design most closely resembles a so - called infinite flat plate ( as vertical control surfaces dramatically increase rcs ), the perfect stealth shape, as it would have no angles to reflect back radar waves. in addition to altering the tail, stealth design must bury the engines within the wing or fuselage, or in some cases where stealth is applied to an extant aircraft, install baffles in the air intakes, so that the compressor blades are not visible to radar. a stealthy shape must be devoid of complex bumps or protrusions of any kind, meaning that weapons, fuel tanks, and other stores must not be carried externally. any stealthy vehicle becomes un - stealthy when a door or hatch opens. parallel alignment of edges or even surfaces is also often used in stealth designs. the technique involves using a small number of edge orientations in the shape of the structure. for example, on the f - 22a raptor, the leading edges of the wing and the tail planes are set at the same angle. other smaller structures, such as the air intake bypass doors and the air refueling aperture, also use the same angles. the effect of this is to return a narrow radar signal in a very specific direction away from the radar emitter rather than returning a diffuse signal detectable at many angles. the effect is sometimes called " glitter " after the very brief signal seen when the reflected beam passes across a detector. it can be difficult for the radar operator to distinguish between a glitter event and a digital glitch in the processing system. stealth airframes sometimes display distinctive serrations on some exposed edges, such as the engine ports. the yf - 23 has such serrations on the exhaust ports. this is another example in the parallel alignment of features, this time on the external airframe. the shaping requirements detracted greatly from the f - 117 ' , behind which are structures termed reentrant triangles. radar waves penetrating the skin get trapped in these structures, reflecting off the internal faces and losing energy. this method was first used on the blackbird series : a - 12, yf - 12a, lockheed sr - 71 blackbird. the most efficient way to reflect radar waves back to the emitting radar is with orthogonal metal plates, forming a corner reflector consisting of either a dihedral ( two plates ) or a trihedral ( three orthogonal plates ). this configuration occurs in the tail of a conventional aircraft, where the vertical and horizontal components of the tail are set at right angles. stealth aircraft such as the f - 117 use a different arrangement, tilting the tail surfaces to reduce corner reflections formed between them. a more radical method is to omit the tail, as in the b - 2 spirit. the b - 2 ' s clean, low - drag flying wing configuration gives it exceptional range and reduces its radar profile. the flying wing design most closely resembles a so - called infinite flat plate ( as vertical control surfaces dramatically increase rcs ), the perfect stealth shape, as it would have no angles to reflect back radar waves. in addition to altering the tail, stealth design must bury the engines within the wing or fuselage, or in some cases where stealth is applied to an extant aircraft, install baffles in the air intakes, so that the compressor blades are not visible to radar. a stealthy shape must be devoid of complex bumps or protrusions of any kind, meaning that weapons, fuel tanks, and other stores must not be carried externally. any stealthy vehicle becomes un - stealthy when a door or hatch opens. parallel alignment of edges or even surfaces is also often used in stealth designs. the technique involves using a small number of edge orientations in the shape of the structure. for example, on the f - 22a raptor, the leading edges of the wing and the tail planes are set at the same angle. other smaller structures, such as the air intake bypass doors and the air refueling aperture, also use the same angles. the effect of this is to return a narrow radar signal in a very specific direction away from the radar emitter rather than returning a diffuse signal detectable at many angles. the effect is sometimes called " glitter " after the very brief signal seen when the reflected beam passes across a detector. it can be difficult for the radar operator to distinguish between a glitter event and a digital glitch in the processing system. stealth air and reduces its radar profile. the flying wing design most closely resembles a so - called infinite flat plate ( as vertical control surfaces dramatically increase rcs ), the perfect stealth shape, as it would have no angles to reflect back radar waves. in addition to altering the tail, stealth design must bury the engines within the wing or fuselage, or in some cases where stealth is applied to an extant aircraft, install baffles in the air intakes, so that the compressor blades are not visible to radar. a stealthy shape must be devoid of complex bumps or protrusions of any kind, meaning that weapons, fuel tanks, and other stores must not be carried externally. any stealthy vehicle becomes un - stealthy when a door or hatch opens. parallel alignment of edges or even surfaces is also often used in stealth designs. the technique involves using a small number of edge orientations in the shape of the structure. for example, on the f - 22a raptor, the leading edges of the wing and the tail planes are set at the same angle. other smaller structures, such as the air intake bypass doors and the air refueling aperture, also use the same angles. the effect of this is to return a narrow radar signal in a very specific direction away from the radar emitter rather than returning a diffuse signal detectable at many angles. the effect is sometimes called " glitter " after the very brief signal seen when the reflected beam passes across a detector. it can be difficult for the radar operator to distinguish between a glitter event and a digital glitch in the processing system. stealth airframes sometimes display distinctive serrations on some exposed edges, such as the engine ports. the yf - 23 has such serrations on the exhaust ports. this is another example in the parallel alignment of features, this time on the external airframe. the shaping requirements detracted greatly from the f - 117 ' s aerodynamic properties. it is inherently unstable, and cannot be flown without a fly - by - wire control system. similarly, coating the cockpit canopy with a thin film transparent conductor ( vapor - deposited gold or indium tin oxide ) helps to reduce the aircraft ' s radar profile, because radar waves would normally enter the cockpit, reflect off objects ( the inside of a cockpit has a complex shape, with a pilot helmet alone forming a sizeable return ), and possibly return to the radar, but the conductive coating creates a controlled shape that deflects the incoming radar waves away from the radar. the coating is thin enough that it has cell - culture scaffolds the material needed for each application is different, and dependent on the desired mechanical properties of the material. tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone ( 100 - 150 mpa ), which is much higher compared to a scaffold for skin regeneration. there are a few versatile synthetic materials used for many different scaffold applications. one of these commonly used materials is polylactic acid ( pla ), a synthetic polymer. pla – polylactic acid. this is a polyester which degrades within the human body to form lactic acid, a naturally occurring chemical which is easily removed from the body. similar materials are polyglycolic acid ( pga ) and polycaprolactone ( pcl ) : their degradation mechanism is similar to that of pla, but pcl degrades slower and pga degrades faster. pla is commonly combined with pga to create poly - lactic - co - glycolic acid ( plga ). this is especially useful because the degradation of plga can be tailored by altering the weight percentages of pla and pga : more pla – slower degradation, more pga – faster degradation. this tunability, along with its biocompatibility, makes it an extremely useful material for scaffold creation. scaffolds may also be constructed from natural materials : in particular different derivatives of the extracellular matrix have been studied to evaluate their ability to support cell growth. protein based materials – such as collagen, or fibrin, and polysaccharidic materials - like chitosan or glycosaminoglycans ( gags ), have all proved suitable in terms of cell compatibility. among gags, hyaluronic acid, possibly in combination with cross linking agents ( e. g. glutaraldehyde, water - soluble carbodiimide, etc. ), is one of the possible choices as scaffold material. due to the covalent attachment of thiol groups to these polymers, they can crosslink via disulfide bond formation. the use of thiolated polymers ( thiomers ) as scaffold material for tissue engineering was initially introduced at the 4th central european symposium on pharmaceutical technology in vienna 2001. as thiomers are biocompatible, exhibit cellular mimicking properties and efficiently support proliferation and differentiation of various cell types, angles. stealth aircraft such as the f - 117 use a different arrangement, tilting the tail surfaces to reduce corner reflections formed between them. a more radical method is to omit the tail, as in the b - 2 spirit. the b - 2 ' s clean, low - drag flying wing configuration gives it exceptional range and reduces its radar profile. the flying wing design most closely resembles a so - called infinite flat plate ( as vertical control surfaces dramatically increase rcs ), the perfect stealth shape, as it would have no angles to reflect back radar waves. in addition to altering the tail, stealth design must bury the engines within the wing or fuselage, or in some cases where stealth is applied to an extant aircraft, install baffles in the air intakes, so that the compressor blades are not visible to radar. a stealthy shape must be devoid of complex bumps or protrusions of any kind, meaning that weapons, fuel tanks, and other stores must not be carried externally. any stealthy vehicle becomes un - stealthy when a door or hatch opens. parallel alignment of edges or even surfaces is also often used in stealth designs. the technique involves using a small number of edge orientations in the shape of the structure. for example, on the f - 22a raptor, the leading edges of the wing and the tail planes are set at the same angle. other smaller structures, such as the air intake bypass doors and the air refueling aperture, also use the same angles. the effect of this is to return a narrow radar signal in a very specific direction away from the radar emitter rather than returning a diffuse signal detectable at many angles. the effect is sometimes called " glitter " after the very brief signal seen when the reflected beam passes across a detector. it can be difficult for the radar operator to distinguish between a glitter event and a digital glitch in the processing system. stealth airframes sometimes display distinctive serrations on some exposed edges, such as the engine ports. the yf - 23 has such serrations on the exhaust ports. this is another example in the parallel alignment of features, this time on the external airframe. the shaping requirements detracted greatly from the f - 117 ' s aerodynamic properties. it is inherently unstable, and cannot be flown without a fly - by - wire control system. similarly, coating the cockpit canopy with a thin film transparent conductor ( vapor - deposited gold or indium tin oxide ) helps to reduce the aircraft ' s radar profile, because radar waves would normally enter the cockpit as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase ##lling, pipe jacking and other operations. a caisson is sunk by self - weight, concrete or water ballast placed on top, or by hydraulic jacks. the leading edge ( or cutting shoe ) of the caisson is sloped out at a sharp angle to aid sinking in a vertical manner ; it is usually made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caissons ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase which constitutes anywhere from 30 % [ m / m ] to 90 % [ m / m ] of its composition by volume, yielding an array of materials with interesting thermomechanical properties. in the processing of glass - ceramics, molten glass is cooled down gradually before reheating and annealing. in this heat s immune system recognizes these re - implanted cells as its own, and does not target them for attack. autologous cell dependence on host cell health and donor site morbidity may be deterrents to their use. adipose - derived and bone marrow - derived mesenchymal stem cells are commonly autologous in nature, and can be used in a myriad of ways, from helping repair skeletal tissue to replenishing beta cells in diabetic patients. allogenic : cells are obtained from the body of a donor of the same species as the recipient. while there are some ethical constraints to the use of human cells for in vitro studies ( i. e. human brain tissue chimera development ), the employment of dermal fibroblasts from human foreskin demonstrates an immunologically safe and thus a viable choice for allogenic tissue engineering of the skin. xenogenic : these cells are derived isolated cells from alternate species from the recipient. a notable example of xenogeneic tissue utilization is cardiovascular implant construction via animal cells. chimeric human - animal farming raises ethical concerns around the potential for improved consciousness from implanting human organs in animals. syngeneic or isogenic : these cells describe those borne from identical genetic code. this imparts an immunologic benefit similar to autologous cell lines ( see above ). autologous cells can be considered syngenic, but the classification also extends to non - autologously derived cells such as those from an identical twin, from genetically identical ( cloned ) research models, or induced stem cells ( isc ) as related to the donor. = = = stem cells = = = stem cells are undifferentiated cells with the ability to divide in culture and give rise to different forms of specialized cells. stem cells are divided into " adult " and " embryonic " stem cells according to their source. while there is still a large ethical debate related to the use of embryonic stem cells, it is thought that another alternative source – induced pluripotent stem cells – may be useful for the repair of diseased or damaged tissues, or may be used to grow new organs. totipotent cells are stem cells which can divide into further stem cells or differentiate into any cell type in the body, including extra - embryonic tissue. pluripotent cells are stem cells which can differentiate into any cell type in the body except extra - embryonic tissue. induced pluripotent stem cells ( ipscs ) Question: The structure of the human tail bone is called what? A) a vestigial structure B) an artifact C) a abnormal structure D) a vital structure	A) a vestigial structure
Context: the project consists to determine, mathematically, the trajectory that will take an artificial satellite to fight against the air resistance. during our work, we had to consider that our satellite will crash to the surface of our planet. we started our study by understanding the system of forces that are acting between our satellite and the earth. in this work, we had to study the second law of newton by taking knowledge of the air friction, the speed of the satellite which helped us to find the equation that relates the trajectory of the satellite itself, its speed and the density of the air depending on the altitude. finally, we had to find a mathematic relation that links the density with the altitude and then we had to put it into our movement equation. in order to verify our model, we ' ll see what happens if we give a zero velocity to the satellite. it seems natural to ask why the universe exists at all. modern physics suggests that the universe can exist all by itself as a self - contained system, without anything external to create or sustain it. but there might not be an absolute answer to why it exists. i argue that any attempt to account for the existence of something rather than nothing must ultimately bottom out in a set of brute facts ; the universe simply is, without ultimate cause or explanation. . this, he argued, would have been more persuasive and would have produced less controversy. the use of poetic imagery based on the concepts of the macrocosm and microcosm, " as above so below " to decide meaning such as edward w. james ' example of " mars above is red, so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : not only is the bekenstein expression for the entropy of a black hole a convex function of the energy, rather than being a concave function as it must be, it predicts a final equilibrium temperature given by the harmonic mean. this violates the third law, and the principle of maximum work. the property that means are monotonically increasing functions of their argument underscores the error of transferring from temperature means to means in the internal energy when the energy is not a monotonically increasing function of temperature. whereas the former leads to an increase in entropy, the latter lead to a decrease in entropy thereby violating the second law. the internal energy cannot increase at a slower rate than the temperature itself. so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : 42 – 48 confirmation bias is a form of cognitive bias. : 553 from the literature, astrology believers often tend to selectively remember those predictions that turned out to be true and do not remember those that turned out false. another, separate, form of confirmation bias also plays a role, where believers often fail to the gravitational acceleration of antimatter, $ \ bar g $, has yet to be directly measured but could change our understanding of gravity, the universe, and the possibility of a fifth force. three avenues are apparent for such a measurement : antihydrogen, positronium, and muonium, the last requiring a precision atom interferometer and benefiting from a novel muonium beam under development. the interferometer and its few - picometer alignment and calibration systems appear to be feasible. with 100 nm grating pitch, measurements of $ \ bar g $ to 10 %, 1 %, or better can be envisioned. this could constitute the first gravitational measurement of leptonic matter, of second - generation matter and, possibly, the first measurement of the gravitational acceleration of antimatter. astronomical observations have shown that the expansion of the universe is at present accelerating, consistently with a constant negative pressure or tension. this is a major puzzle because we do not understand why this tension is so small compared to the planck density ; why, being so small, it is not exactly zero ; and why it has precisely the required value to make the expansion start accelerating just at the epoch when we are observing the universe. the recently proposed conjecture by afshordi that black holes create a gravitational aether owing to quantum gravity effects, which may be identified with this invisible tension, can solve this coincidence problem. the fact that the expansion of the universe is starting to accelerate at the epoch when we observe it is a necessity that is implied by our origin in a planet orbiting a star that formed when the age of the universe was of the same order as the lifetime of the star. this argument is unrelated to any anthropic reasoning. endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer the gravitational poynting vector provides a mechanism for the transfer of gravitational energy to a system of falling objects. in the following we will show that the gravitational poynting vector together with the gravitational larmor theorem also provides a mechanism to explain how massive bodies acquire rotational kinetic energy when external mechanical forces are applied on them. the large scale pattern in the arrival directions of extragalactic cosmic rays that reach the earth is different from that of the flux arriving to the halo of the galaxy as a result of the propagation through the galactic magnetic field. two different effects are relevant in this process : deflections of trajectories and ( de ) acceleration by the electric field component due to the galactic rotation. the deflection of the cosmic ray trajectories makes the flux intensity arriving to the halo from some direction to appear reaching the earth from another direction. this applies to any intrinsic anisotropy in the extragalactic distribution or, even in the absence of intrinsic anisotropies, to the dipolar compton - getting anisotropy induced when the observer is moving with respect to the cosmic rays rest frame. for an observer moving with the solar system, cosmic rays traveling through far away regions of the galaxy also experience an electric force coming from the relative motion ( due to the rotation of the galaxy ) of the local system in which the field can be considered as being purely magnetic. this produces small changes in the particles momentum that can originate large scale anisotropies even for an isotropic extragalactic flux. Question: Of course, a net external force is needed to cause any acceleration, just as newton proposed in his second law of what? A) motion B) speed C) gravity D) land	A) motion
Context: they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became . microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of ##rozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokar pectin and xyloglucan from which the land plant cell wall is constructed. vascular land plants make lignin, a polymer used to strengthen the secondary cell walls of xylem tracheids and vessels to keep them from collapsing when a plant sucks water through them under water stress. lignin is also used in other cell types like sclerenchyma fibres that provide structural support for a plant and is a major constituent of wood. sporopollenin is a chemically resistant polymer found in the outer cell walls of spores and pollen of land plants responsible for the survival of early land plant spores and the pollen of seed plants in the fossil record. it is widely regarded as a marker for the start of land plant evolution during the ordovician period. the concentration of carbon dioxide in the atmosphere today is much lower than it was when plants emerged onto land during the ordovician and silurian periods. many monocots like maize and the pineapple and some dicots like the asteraceae have since independently evolved pathways like crassulacean acid metabolism and the c4 carbon fixation pathway for photosynthesis which avoid the losses resulting from photorespiration in the more common c3 carbon fixation pathway. these biochemical strategies are unique to land plants. = = = medicine and materials = = = phytochemistry is a branch of plant biochemistry primarily concerned with the chemical substances produced by plants during secondary metabolism. some of these compounds are toxins such as the alkaloid coniine from hemlock. others, such as the essential oils peppermint oil and lemon oil are useful for their aroma, as flavourings and spices ( e. g., capsaicin ), and in medicine as pharmaceuticals as in opium from opium poppies. many medicinal and recreational drugs, such as tetrahydrocannabinol ( active ingredient in cannabis ), caffeine, morphine and nicotine come directly from plants. others are simple derivatives of botanical natural products. for example, the pain killer aspirin is the acetyl ester of salicylic acid, originally isolated from the bark of willow trees, and a wide range of opiate painkillers like heroin are obtained by chemical modification of morphine obtained from the opium poppy. popular stimulants come from plants, such as caffeine from coffee, tea and chocolate, and nicotine from tobacco. most alcoholic beverages come from fermentation of carbohy , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive of embryophytes ( land plants ) is called phytology. bryology is the study of mosses ( and in the broader sense also liverworts and hornworts ). pteridology ( or filicology ) is the study of ferns and allied plants. a number of other taxa of ranks varying from family to subgenus have terms for their study, including agrostology ( or graminology ) for the study of grasses, synantherology for the study of composites, and batology for the study of brambles. study can also be divided by guild rather than clade or grade. for example, dendrology is the study of woody plants. many divisions of biology have botanical subfields. these are commonly denoted by prefixing the word plant ( e. g. plant taxonomy, plant ecology, plant anatomy, plant morphology, plant systematics ), or prefixing or substituting the prefix phyto - ( e. g. phytochemistry, phytogeography ). the study of fossil plants is called palaeobotany. other fields are denoted by adding or substituting the word botany ( e. g. systematic botany ). phytosociology is a subfield of plant ecology that classifies and studies communities of plants. the intersection of fields from the above pair of categories gives rise to fields such as bryogeography, the study of the distribution of mosses. different parts of plants also give rise to their own subfields, including xylology, carpology ( or fructology ), and palynology, these being the study of wood, fruit and pollen / spores respectively. botany also overlaps on the one hand with agriculture, horticulture and silviculture, and on the other hand with medicine and pharmacology, giving rise to fields such as agronomy, horticultural botany, phytopathology, and phytopharmacology. = = scope and importance = = the study of plants is vital because they underpin almost all animal life on earth by generating a large proportion of the oxygen and food that provide humans and other organisms with aerobic respiration with the chemical energy they need to exist. plants, algae and cyanobacteria are the major groups of organisms that carry out photosynthesis, a process that uses the energy of sunlight to convert water and carbon dioxide into sugars that can be used both as a source of chemical energy and of organic molecules that are used in ancient endosymbiotic relationship between an ancestral eukaryotic cell and a cyanobacterial resident. the algae are a polyphyletic group and are placed in various divisions, some more closely related to plants than others. there are many differences between them in features such as cell wall composition, biochemistry, pigmentation, chloroplast structure and nutrient reserves. the algal division charophyta, sister to the green algal division chlorophyta, is considered to contain the ancestor of true plants. the charophyte class charophyceae and the land plant sub - kingdom embryophyta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an o into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off with one allele inducing a change on the other. = = plant evolution = = the chloroplasts of plants have a number of biochemical, structural and genetic similarities to cyanobacteria, ( commonly but incorrectly known as " blue - green algae " ) and are thought to be derived from an ancient endosymbiotic relationship between an ancestral eukaryotic cell and a cyanobacterial resident. the algae are a polyphyletic group and are placed in various divisions, some more closely related to plants than others. there are many differences between them in features such as cell wall composition, biochemistry, pigmentation, chloroplast structure and nutrient reserves. the algal division charophyta, sister to the green algal division chlorophyta, is considered to contain the ancestor of true plants. the charophyte class charophyceae and the land plant sub - kingdom embryophyta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gym Question: The oldest fossil of land plants date back how many millions of years? A) 520 million years B) 430 million years C) 350 million years D) 470 million years	D) 470 million years
Context: ceramic constituents, the greatest attention is on composites in which all constituents are ceramic. these typically comprise two ceramic constituents : a continuous matrix, and a dispersed phase of ceramic particles, whiskers, or short ( chopped ) or continuous ceramic fibers. the challenge, as in wet chemical processing, is to obtain a uniform or homogeneous distribution of the dispersed particle or fiber phase. consider first the processing of particulate composites. the particulate phase of greatest interest is tetragonal zirconia because of the toughening that can be achieved from the phase transformation from the metastable tetragonal to the monoclinic crystalline phase, aka transformation toughening. there is also substantial interest in dispersion of hard, non - oxide phases such as sic, tib, tic, boron, carbon and especially oxide matrices like alumina and mullite. there is also interest too incorporating other ceramic particulates, especially those of highly anisotropic thermal expansion. examples include al2o3, tio2, graphite, and boron nitride. in processing particulate composites, the issue is not only homogeneity of the size and spatial distribution of the dispersed and matrix phases, but also control of the matrix grain size. however, there is some built - in self - control due to inhibition of matrix grain growth by the dispersed phase. particulate composites, though generally offer increased resistance to damage, failure, or both, are still quite sensitive to inhomogeneities of composition as well as other processing defects such as pores. thus they need good processing to be effective. particulate composites have been made on a commercial basis by simply mixing powders of the two constituents. although this approach is inherently limited in the homogeneity that can be achieved, it is the most readily adaptable for existing ceramic production technology. however, other approaches are of interest. from the technological standpoint, a particularly desirable approach to fabricating particulate composites is to coat the matrix or its precursor onto fine particles of the dispersed phase with good control of the starting dispersed particle size and the resultant matrix coating thickness. one should in principle be able to achieve the ultimate in homogeneity of distribution and thereby optimize composite performance. this can also have other ramifications, such as allowing more useful composite performance to be achieved in a body having porosity, which might be desired for other factors, such as limiting thermal conductivity. there are also some opportunities to ##electronics and mems in particular. silicon nanowires, fabricated through the thermal oxidation of silicon, are of further interest in electrochemical conversion and storage, including nanowire batteries and photovoltaic systems. polymers even though the electronics industry provides an economy of scale for the silicon industry, crystalline silicon is still a complex and relatively expensive material to produce. polymers on the other hand can be produced in huge volumes, with a great variety of material characteristics. mems devices can be made from polymers by processes such as injection molding, embossing or stereolithography and are especially well suited to microfluidic applications such as disposable blood testing cartridges. metals metals can also be used to create mems elements. while metals do not have some of the advantages displayed by silicon in terms of mechanical properties, when used within their limitations, metals can exhibit very high degrees of reliability. metals can be deposited by electroplating, evaporation, and sputtering processes. commonly used metals include gold, nickel, aluminium, copper, chromium, titanium, tungsten, platinum, and silver. ceramics the nitrides of silicon, aluminium and titanium as well as silicon carbide and other ceramics are increasingly applied in mems fabrication due to advantageous combinations of material properties. aln crystallizes in the wurtzite structure and thus shows pyroelectric and piezoelectric properties enabling sensors, for instance, with sensitivity to normal and shear forces. tin, on the other hand, exhibits a high electrical conductivity and large elastic modulus, making it possible to implement electrostatic mems actuation schemes with ultrathin beams. moreover, the high resistance of tin against biocorrosion qualifies the material for applications in biogenic environments. the figure shows an electron - microscopic picture of a mems biosensor with a 50 nm thin bendable tin beam above a tin ground plate. both can be driven as opposite electrodes of a capacitor, since the beam is fixed in electrically isolating side walls. when a fluid is suspended in the cavity its viscosity may be derived from bending the beam by electrical attraction to the ground plate and measuring the bending velocity. = = basic processes = = = = = deposition processes = = = one of the basic building blocks in mems processing is the ability to deposit thin films of material with a thickness anywhere from one micrometre to about 100 micrometres. the nems process is the same, still a complex and relatively expensive material to produce. polymers on the other hand can be produced in huge volumes, with a great variety of material characteristics. mems devices can be made from polymers by processes such as injection molding, embossing or stereolithography and are especially well suited to microfluidic applications such as disposable blood testing cartridges. metals metals can also be used to create mems elements. while metals do not have some of the advantages displayed by silicon in terms of mechanical properties, when used within their limitations, metals can exhibit very high degrees of reliability. metals can be deposited by electroplating, evaporation, and sputtering processes. commonly used metals include gold, nickel, aluminium, copper, chromium, titanium, tungsten, platinum, and silver. ceramics the nitrides of silicon, aluminium and titanium as well as silicon carbide and other ceramics are increasingly applied in mems fabrication due to advantageous combinations of material properties. aln crystallizes in the wurtzite structure and thus shows pyroelectric and piezoelectric properties enabling sensors, for instance, with sensitivity to normal and shear forces. tin, on the other hand, exhibits a high electrical conductivity and large elastic modulus, making it possible to implement electrostatic mems actuation schemes with ultrathin beams. moreover, the high resistance of tin against biocorrosion qualifies the material for applications in biogenic environments. the figure shows an electron - microscopic picture of a mems biosensor with a 50 nm thin bendable tin beam above a tin ground plate. both can be driven as opposite electrodes of a capacitor, since the beam is fixed in electrically isolating side walls. when a fluid is suspended in the cavity its viscosity may be derived from bending the beam by electrical attraction to the ground plate and measuring the bending velocity. = = basic processes = = = = = deposition processes = = = one of the basic building blocks in mems processing is the ability to deposit thin films of material with a thickness anywhere from one micrometre to about 100 micrometres. the nems process is the same, although the measurement of film deposition ranges from a few nanometres to one micrometre. there are two types of deposition processes, as follows. = = = = physical deposition = = = = physical vapor deposition ( " pvd " ) consists of a process in which a material is removed from a target, and ##ubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - 20 °c or lower until required. by using culture supernatant or a purified immunoglobulin preparation, further analysis of a potential monoclonal antibody producing hybridoma can be made in terms of reactivity, specificity, and cross - reactivity. = = applications = = the use of monoclonal antibodies is numerous and includes the prevention, diagnosis, and treatment of disease. for example, monoclonal antibodies can distinguish subsets of b cells and t cells, which is helpful in identifying different types of leukaemias. in addition, specific monoclonal antibodies have been used to define cell surface markers on white blood cells and other cell types. this led to the cluster of differentiation series of markers. these are often referred to as cd markers and define several hundred different cell surface components of cells, each specified by binding of a particular monoclonal antibody. such antibodies are extremely useful for fluorescence - activated cell sorting, ##gnant cells. the use of monoclonal antibodies ( mabs ) specific for cytokeratins can identify disseminated individual epithelial tumor cells in the bone marrow. one study reports on having developed an immuno - cytochemical procedure for simultaneous labeling of cytokeratin component no. 18 ( ck18 ) and prostate specific antigen ( psa ). this would help in the further characterization of disseminated individual epithelial tumor cells in patients with prostate cancer. the twelve control aspirates from patients with benign prostatic hyperplasia showed negative staining, which further supports the specificity of ck18 in detecting epithelial tumour cells in bone marrow. in most cases of malignant disease complicated by effusion, neoplastic cells can be easily recognized. however, in some cases, malignant cells are not so easily seen or their presence is too doubtful to call it a positive report. the use of immuno - cytochemical techniques increases diagnostic accuracy in these cases. ghosh, mason and spriggs analysed 53 samples of pleural or peritoneal fluid from 41 patients with malignant disease. conventional cytological examination had not revealed any neoplastic cells. three monoclonal antibodies ( anti - cea, ca 1 and hmfg - 2 ) were used to search for malignant cells. immunocytochemical labelling was performed on unstained smears, which had been stored at - 20 °c up to 18 months. twelve of the forty - one cases in which immuno - cytochemical staining was performed, revealed malignant cells. the result represented an increase in diagnostic accuracy of approximately 20 %. the study concluded that in patients with suspected malignant disease, immuno - cytochemical labeling should be used routinely in the examination of cytologically negative samples and has important implications with respect to patient management. another application of immuno - cytochemical staining is for the detection of two antigens in the same smear. double staining with light chain antibodies and with t and b cell markers can indicate the neoplastic origin of a lymphoma. one study has reported the isolation of a hybridoma cell line ( clone 1e10 ), which produces a monoclonal antibody ( igm, k isotype ). this monoclonal antibody shows specific immuno - cytochemical staining of nucleoli. tissues and tumours can it is perceived as a threat or manageable obstacle ) ; finally, the ' x ' indicates the crisis ( the overall experience and response to the stressor that either strengthens or weakens families / couples ). see figure 1. in 1977, 1979, and 1986, urie bronfenbrenner published a model that integrated the multiple different levels or domains of an individual ' s environment. it was first developed to apply to child development, but has been widely applied in relationship science. the first level is the microsystem, which contains the single, immediate context people or dyads ( e. g., couple, parent - child, friends ) directly find themselves in — such as a home, school, or work. the second level is the mesosystem, which considers the combined effects of two or more contexts / settings. the third level is the exosystem, which also considers the effects of two or more contexts, but specifically contains at least one context that the individual or dyad is not directly in ( e. g., government, social services ) but affects an environment they are directly in ( e. g., home, work ). the fourth level is the macrosystem, which is the broader cultural and social attitudes that affect an individual. finally, the chronosystem is the broadest level that is specifically the dimension of time as it relates to an individual ' s context changes and life events. see figure 2. researchers in relationship science have used social ecological models to study changes and stressors in relationships over time, and how couples, families, or even friends manage them given the contexts they evolve in. application of social ecological models in relationship research have been seen in influential works such as benjamin karney and thomas bradbury ' s vulnerability - stress - adaptation ( vsa ) model. the vsa model is a theoretical approach that enables researchers to study the impact of stressful events on relationship quality and stability over time ( e. g., determine risk of divorce / relationship dissolution ), given a couple ' s capacity to manage and adapt to such events. see figure 3. = = = = relational mobility = = = = in the early 2000s, a japan - based research team defined relational mobility as a measure of how much choice individuals have in terms of whom to form relationships with, including friendships, romantic partnerships, and work relations. relational mobility is low in cultures with a subsistence economy that requires tight cooperation and coordination, such as farming, while it is the work studies some difference equations, which are connected with mejer ' s function. ##olithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures left no written records, the shift from nomadic life to settlement and agriculture can be inferred from a range of archaeological evidence. such evidence includes ancient tools, cave paintings, and other prehistoric art, such as the venus of willendorf. human remains also provide direct evidence, both through the examination of bones, and the study of mummies. scientists and historians have been able to form significant inferences about the lifestyle and culture of various prehistoric peoples, and especially their technology. = = = ancient = = = = = = = copper and bronze ages = = = = metallic copper occurs on the surface of weathered copper ore deposits and copper was used before copper smelting was known. copper smelting is believed to have originated when the technology of pottery kilns allowed sufficiently high temperatures. the concentration of various elements such as arsenic increase with depth in copper ore deposits and smelting of these ores yields arsenical bronze, which can be sufficiently work hardened to be suitable for making tools. bronze is an alloy of copper with tin ; the latter being found in relatively few deposits globally caused a long time to elapse before true tin bronze became widespread. ( see : tin sources and trade in ancient times ) bronze was a major advancement over stone as a material for ##ry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - 20 °c or lower until required. by using culture supernatant or a purified immunoglobulin preparation, further analysis of a potential monoclonal antibody producing hybridoma can be made in terms of reactivity, specificity, and cross - reactivity. = = applications = = the use of monoclonal antibodies is numerous and includes the prevention, diagnosis, and treatment of disease. for example, monoclonal antibodies can distinguish subsets of b cells and t cells, which is helpful in identifying different types of leukaemias. in addition, specific monoclonal antibodies have been used to define cell surface markers on white blood cells and other cell types. this led to the cluster of differentiation series of markers. these are often referred to as cd markers and define several hundred different cell surface components of cells, each specified by binding of a particular monoclonal antibody. such antibodies are extremely useful for fluorescence - activated cell sorting, the specific isolation of particular types of cells. = = = in diagnostic histopathology = = = with the help of monoclonal antibodies, tissues and organs can be classified based on their expression of certain defined markers, which reflect tissue or cellular genesis. prostate specific antigen, placental alkaline phospha the specific isolation of particular types of cells. = = = in diagnostic histopathology = = = with the help of monoclonal antibodies, tissues and organs can be classified based on their expression of certain defined markers, which reflect tissue or cellular genesis. prostate specific antigen, placental alkaline phosphatase, human chorionic gonadotrophin, α - fetoprotein and others are organ - associated antigens and the production of monoclonal antibodies against these antigens helps in determining the nature of a primary tumor. monoclonal antibodies are especially useful in distinguishing morphologically similar lesions, like pleural and peritoneal mesothelioma, adenocarcinoma, and in the determination of the organ or tissue origin of undifferentiated metastases. selected monoclonal antibodies help in the detection of occult metastases ( cancer of unknown primary origin ) by immuno - cytological analysis of bone marrow, other tissue aspirates, as well as lymph nodes and other tissues and can have increased sensitivity over normal histopathological staining. one study performed a sensitive immuno - histochemical assay on bone marrow aspirates of 20 patients with localized prostate cancer. three monoclonal antibodies ( t16, c26, and ae - 1 ), capable of recognizing membrane and cytoskeletal antigens expressed by epithelial cells to detect tumour cells, were used in the assay. bone marrow aspirates of 22 % of patients with localized prostate cancer ( stage b, 0 / 5 ; stage c, 2 / 4 ), and 36 % patients with metastatic prostate cancer ( stage d1, 0 / 7 patients ; stage d2, 4 / 4 patients ) had antigen - positive cells in their bone marrow. it was concluded that immuno - histochemical staining of bone marrow aspirates are very useful to detect occult bone marrow metastases in patients with apparently localized prostate cancer. although immuno - cytochemistry using tumor - associated monoclonal antibodies has led to an improved ability to detect occult breast cancer cells in bone marrow aspirates and peripheral blood, further development of this method is necessary before it can be used routinely. one major drawback of immuno - cytochemistry is that only tumor - associated and not tumor - specific monoclonal antibodies are used, and as a result, some cross - reaction with normal cells can occur Question: What do young female meerkats act as in colonies? A) midwives B) predators C) babysitters D) defenders	C) babysitters
Context: made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caissons ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up are the stone - paved streets of the city - state of ur, dating to c. 4, 000 bce, and timber roads leading through the swamps of glastonbury, england, dating to around the same period. the first long - distance road, which came into use around 3, 500 bce, spanned 2, 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans also had a complex system of aqueducts, which were used to transport water across long distances. the first roman aqueduct was built in 312 bce. the eleventh and final ancient roman aqueduct was built in 226 ce. put together, the roman aqueducts extended over 450 km, but less than 70 km of this was above ground and supported by arches. = = = pre - modern = = = innovations continued through the middle ages with the introduction of silk production ( in asia and later europe ), the horse collar, and horseshoes. simple machines ( such as the lever, the screw, and the pulley ) were combined into more complicated tools, such as the wheelbarrow, windmills, and clocks. a system of universities developed and spread scientific ideas and practices, including oxford and cambridge. the renaissance era produced many innovations, including the introduction of the movable type printing press to europe, which facilitated the communication of knowledge. technology became increasingly influenced by science, beginning a cycle of mutual advancement. = = = modern = = = starting in the united kingdom in the 18th century, the discovery of steam power set off the industrial revolution, which saw wide - ranging technological discoveries, particularly in the areas of agriculture, manufacturing, mining, metallurgy, and transport, and the ##lling, pipe jacking and other operations. a caisson is sunk by self - weight, concrete or water ballast placed on top, or by hydraulic jacks. the leading edge ( or cutting shoe ) of the caisson is sloped out at a sharp angle to aid sinking in a vertical manner ; it is usually made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caissons ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy ". = = extraction = = extractive metallurgy is the practice of removing valuable metals from an ore and refining the extracted raw metals into a purer form. in order to convert a metal oxide or sulphide to a purer metal, the ore must be reduced physically, chemically, or electrolytically. extractive metallurgists are interested in three primary streams : feed, concentrate ( metal oxide / sulphide ) and tailings ( waste ). after mining, large pieces of the ore feed are broken through crushing or grinding in order to obtain particles small enough, where each particle is either mostly valuable or mostly waste. concentrating the particles of value in a form supporting separation enables the desired metal to be removed from waste products. mining may not be necessary, if the ore body and physical environment are conducive to leaching. leaching dissolves minerals in an ore body and results in an enriched solution. the solution remediation include ; soil contamination, hazardous waste, groundwater contamination, oil, gas and chemical spills. there are three most common types of environmental remediation. these include soil, water, and sediment remediation. soil remediation consists of removing contaminants in soil, as these pose great risks to humans and the ecosystem. some examples of this are heavy metals, pesticides, and radioactive materials. depending on the contaminant the remedial processes can be physical, chemical, thermal, or biological. water remediation is one of the most important considering water is an essential natural resource. depending on the source of water there will be different contaminants. surface water contamination mainly consists of agricultural, animal, and industrial waste, as well as acid mine drainage. there has been a rise in the need for water remediation due to the increased discharge of industrial waste, leading to a demand for sustainable water solutions. the market for water remediation is expected to consistently increase to $ 19. 6 billion by 2030. sediment remediation consists of removing contaminated sediments. is it almost similar to soil remediation except it is often more sophisticated as it involves additional contaminants. to reduce the contaminants it is likely to use physical, chemical, and biological processes that help with source control, but if these processes are executed correctly, there ' s a risk of contamination resurfacing. = = = solid waste management = = = solid waste management is the purification, consumption, reuse, disposal, and treatment of solid waste that is undertaken by the government or the ruling bodies of a city / town. it refers to the collection, treatment, and disposal of non - soluble, solid waste material. solid waste is associated with both industrial, institutional, commercial and residential activities. hazardous solid waste, when improperly disposed can encourage the infestation of insects and rodents, contributing to the spread of diseases. some of the most common types of solid waste management include ; landfills, vermicomposting, composting, recycling, and incineration. however, a major barrier for solid waste management practices is the high costs associated with recycling and the risks of creating more pollution. = = = e - waste recycling = = = the recycling of electronic waste ( e - waste ) has seen significant technological advancements due to increasing environmental concerns and the growing volume of electronic product disposals. traditional e - waste recycling methods, which often involve manual disassemb ##thic, or " old stone age ", and spans all of human history up to the development of agriculture approximately 12, 000 years ago. to make a stone tool, a " core " of hard stone with specific flaking properties ( such as flint ) was struck with a hammerstone. this flaking produced sharp edges which could be used as tools, primarily in the form of choppers or scrapers. these tools greatly aided the early humans in their hunter - gatherer lifestyle to perform a variety of tasks including butchering carcasses ( and breaking bones to get at the marrow ) ; chopping wood ; cracking open nuts ; skinning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures , 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans also had a complex system of aqueducts, which were used to transport water across long distances. the first roman aqueduct was built in 312 bce. the eleventh and final ancient roman aqueduct was built in 226 ce. put together, the roman aqueducts extended over 450 km, but less than 70 km of this was above ground and supported by arches. = = = pre - modern = = = innovations continued through the middle ages with the introduction of silk production ( in asia and later europe ), the horse collar, and horseshoes. simple machines ( such as the lever, the screw, and the pulley ) were combined into more complicated tools, such as the wheelbarrow, windmills, and clocks. a system of universities developed and spread scientific ideas and practices, including oxford and cambridge. the renaissance era produced many innovations, including the introduction of the movable type printing press to europe, which facilitated the communication of knowledge. technology became increasingly influenced by science, beginning a cycle of mutual advancement. = = = modern = = = starting in the united kingdom in the 18th century, the discovery of steam power set off the industrial revolution, which saw wide - ranging technological discoveries, particularly in the areas of agriculture, manufacturing, mining, metallurgy, and transport, and the widespread application of the factory system. this was followed a century later by the second industrial revolution which led to rapid scientific discovery, standardization, and mass production. new technologies were developed, including sewage systems, electricity, light bulbs, electric motors, railroads, automobiles, and airplanes. these technological advances led to significant developments in medicine c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy ". = = extraction = = extractive metallurgy is the practice of removing valuable metals from an ore and refining the extracted raw metals into a purer form. in order to convert a metal oxide or sulphide to a purer metal, the ore must be reduced physically, chemically, or electroly river - beds ), but not for where there may be large obstructions in the ground. an open caisson that is used in soft grounds or high water tables, where open trench excavations are impractical, can also be used to install deep manholes, pump stations and reception / launch pits for microtunnelling, pipe jacking and other operations. a caisson is sunk by self - weight, concrete or water ballast placed on top, or by hydraulic jacks. the leading edge ( or cutting shoe ) of the caisson is sloped out at a sharp angle to aid sinking in a vertical manner ; it is usually made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caisson ##ning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures left no written records, the shift from nomadic life to settlement and agriculture can be inferred from a range of archaeological evidence. such evidence includes ancient tools, cave paintings, and other prehistoric art, such as the venus of willendorf. human remains also provide direct evidence, both through the examination of bones, and Question: Since europeans settled in the united states, about what percentage of topsoil has eroded away? A) 33 percent B) 25 percent C) 10 percent D) 42 percent	A) 33 percent
Context: have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became diagnosis and management of hereditary disorders. neurology is concerned with diseases of the nervous system. in the uk, neurology is a subspecialty of general medicine. obstetrics and gynecology ( often abbreviated as ob / gyn ( american english ) or obs & gynae ( british english ) ) are concerned respectively with childbirth and the female reproductive and associated organs. reproductive medicine and fertility medicine are generally practiced by gynecological specialists. pediatrics ( ae ) or paediatrics ( be ) is devoted to the care of infants, children, and adolescents. like internal medicine, there are many pediatric subspecialties for specific age ranges, organ systems, disease classes, and sites of care delivery. pharmaceutical medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of marketing of medicines for the benefit of patients and public health. physical medicine and rehabilitation ( or physiatry ) is concerned with functional improvement after injury, illness, or congenital disorders. podiatric medicine is the study of, diagnosis, and medical and surgical treatment of disorders of the foot, ankle, lower limb, hip and lower back. preventive medicine is the branch of medicine concerned with preventing disease. community health or public health is an aspect of health services concerned with threats to the overall health of a community based on population health analysis. psychiatry is the branch of medicine concerned with the bio - psycho - social study of the etiology, diagnosis, treatment and prevention of cognitive, perceptual, emotional and behavioral disorders. related fields include psychotherapy and clinical psychology. = = = interdisciplinary fields = = = some interdisciplinary sub - specialties of medicine include : addiction medicine deals with the treatment of addiction. aerospace medicine deals with medical problems related to flying and space travel. biomedical engineering is a field dealing with the application of engineering principles to medical practice. clinical pharmacology is concerned with how systems of therapeutics interact with patients. conservation medicine studies the relationship between human and non - human animal health, and environmental conditions. also known as ecological medicine, environmental medicine, or medical geology. disaster medicine deals with medical aspects of emergency preparedness, disaster mitigation and management. diving medicine ( or hyperbaric medicine ) is the prevention and treatment of diving - related problems. evolutionary medicine is a perspective on medicine derived through applying evolutionary theory. forensic medicine deals with medical questions in legal context, such as determination of the time and cause of death, type of weapon used to inflict english ) ) are concerned respectively with childbirth and the female reproductive and associated organs. reproductive medicine and fertility medicine are generally practiced by gynecological specialists. pediatrics ( ae ) or paediatrics ( be ) is devoted to the care of infants, children, and adolescents. like internal medicine, there are many pediatric subspecialties for specific age ranges, organ systems, disease classes, and sites of care delivery. pharmaceutical medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of marketing of medicines for the benefit of patients and public health. physical medicine and rehabilitation ( or physiatry ) is concerned with functional improvement after injury, illness, or congenital disorders. podiatric medicine is the study of, diagnosis, and medical and surgical treatment of disorders of the foot, ankle, lower limb, hip and lower back. preventive medicine is the branch of medicine concerned with preventing disease. community health or public health is an aspect of health services concerned with threats to the overall health of a community based on population health analysis. psychiatry is the branch of medicine concerned with the bio - psycho - social study of the etiology, diagnosis, treatment and prevention of cognitive, perceptual, emotional and behavioral disorders. related fields include psychotherapy and clinical psychology. = = = interdisciplinary fields = = = some interdisciplinary sub - specialties of medicine include : addiction medicine deals with the treatment of addiction. aerospace medicine deals with medical problems related to flying and space travel. biomedical engineering is a field dealing with the application of engineering principles to medical practice. clinical pharmacology is concerned with how systems of therapeutics interact with patients. conservation medicine studies the relationship between human and non - human animal health, and environmental conditions. also known as ecological medicine, environmental medicine, or medical geology. disaster medicine deals with medical aspects of emergency preparedness, disaster mitigation and management. diving medicine ( or hyperbaric medicine ) is the prevention and treatment of diving - related problems. evolutionary medicine is a perspective on medicine derived through applying evolutionary theory. forensic medicine deals with medical questions in legal context, such as determination of the time and cause of death, type of weapon used to inflict trauma, reconstruction of the facial features using remains of deceased ( skull ) thus aiding identification. gender - based medicine studies the biological and physiological differences between the human sexes and how that affects differences in disease. health informatics is a relatively recent field that deal with the application of computers and information technology to medicine. hospice and pal practice, general practice or primary care is, in many countries, the first port - of - call for patients with non - emergency medical problems. family physicians often provide services across a broad range of settings including office based practices, emergency department coverage, inpatient care, and nursing home care. medical genetics is concerned with the diagnosis and management of hereditary disorders. neurology is concerned with diseases of the nervous system. in the uk, neurology is a subspecialty of general medicine. obstetrics and gynecology ( often abbreviated as ob / gyn ( american english ) or obs & gynae ( british english ) ) are concerned respectively with childbirth and the female reproductive and associated organs. reproductive medicine and fertility medicine are generally practiced by gynecological specialists. pediatrics ( ae ) or paediatrics ( be ) is devoted to the care of infants, children, and adolescents. like internal medicine, there are many pediatric subspecialties for specific age ranges, organ systems, disease classes, and sites of care delivery. pharmaceutical medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of marketing of medicines for the benefit of patients and public health. physical medicine and rehabilitation ( or physiatry ) is concerned with functional improvement after injury, illness, or congenital disorders. podiatric medicine is the study of, diagnosis, and medical and surgical treatment of disorders of the foot, ankle, lower limb, hip and lower back. preventive medicine is the branch of medicine concerned with preventing disease. community health or public health is an aspect of health services concerned with threats to the overall health of a community based on population health analysis. psychiatry is the branch of medicine concerned with the bio - psycho - social study of the etiology, diagnosis, treatment and prevention of cognitive, perceptual, emotional and behavioral disorders. related fields include psychotherapy and clinical psychology. = = = interdisciplinary fields = = = some interdisciplinary sub - specialties of medicine include : addiction medicine deals with the treatment of addiction. aerospace medicine deals with medical problems related to flying and space travel. biomedical engineering is a field dealing with the application of engineering principles to medical practice. clinical pharmacology is concerned with how systems of therapeutics interact with patients. conservation medicine studies the relationship between human and non - human animal health, and environmental conditions. also known as ecological medicine, environmental medicine, or medical geology. disaster medicine deals with medical aspects of emergency preparedness, disaster mitigation . the first major technologies were tied to survival, hunting, and food preparation. stone tools and weapons, fire, and clothing were technological developments of major importance during this period. human ancestors have been using stone and other tools since long before the emergence of homo sapiens approximately 300, 000 years ago. the earliest direct evidence of tool usage was found in ethiopia within the great rift valley, dating back to 2. 5 million years ago. the earliest methods of stone tool making, known as the oldowan " industry ", date back to at least 2. 3 million years ago. this era of stone tool use is called the paleolithic, or " old stone age ", and spans all of human history up to the development of agriculture approximately 12, 000 years ago. to make a stone tool, a " core " of hard stone with specific flaking properties ( such as flint ) was struck with a hammerstone. this flaking produced sharp edges which could be used as tools, primarily in the form of choppers or scrapers. these tools greatly aided the early humans in their hunter - gatherer lifestyle to perform a variety of tasks including butchering carcasses ( and breaking bones to get at the marrow ) ; chopping wood ; cracking open nuts ; skinning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = meiosis is a central feature of sexual reproduction in eukaryotes, and the most fundamental function of meiosis appears to be conservation of the integrity of the genome that is passed on to progeny by parents. two aspects of sexual reproduction, meiotic recombination and outcrossing, are likely maintained respectively by astronomical observations have shown that the expansion of the universe is at present accelerating, consistently with a constant negative pressure or tension. this is a major puzzle because we do not understand why this tension is so small compared to the planck density ; why, being so small, it is not exactly zero ; and why it has precisely the required value to make the expansion start accelerating just at the epoch when we are observing the universe. the recently proposed conjecture by afshordi that black holes create a gravitational aether owing to quantum gravity effects, which may be identified with this invisible tension, can solve this coincidence problem. the fact that the expansion of the universe is starting to accelerate at the epoch when we observe it is a necessity that is implied by our origin in a planet orbiting a star that formed when the age of the universe was of the same order as the lifetime of the star. this argument is unrelated to any anthropic reasoning. the resulting entity is a genetically modified organism ( gmo ). the first gmo was a bacterium generated by herbert boyer and stanley cohen in 1973. rudolf jaenisch created the first gm animal when he inserted foreign dna into a mouse in 1974. the first company to focus on genetic engineering, genentech, was founded in 1976 and started the production of human proteins. genetically engineered human insulin was produced in 1978 and insulin - producing bacteria were commercialised in 1982. genetically modified food has been sold since 1994, with the release of the flavr savr tomato. the flavr savr was engineered to have a longer shelf life, but most current gm crops are modified to increase resistance to insects and herbicides. glofish, the first gmo designed as a pet, was sold in the united states in december 2003. in 2016 salmon modified with a growth hormone were sold. genetic engineering has been applied in numerous fields including research, medicine, industrial biotechnology and agriculture. in research, gmos are used to study gene function and expression through loss of function, gain of function, tracking and expression experiments. by knocking out genes responsible for certain conditions it is possible to create animal model organisms of human diseases. as well as producing hormones, vaccines and other drugs, genetic engineering has the potential to cure genetic diseases through gene therapy. chinese hamster ovary ( cho ) cells are used in industrial genetic engineering. additionally mrna vaccines are made through genetic engineering to prevent infections by viruses such as covid - 19. the same techniques that are used to produce drugs can also have industrial applications such as producing enzymes for laundry detergent, cheeses and other products. the rise of commercialised genetically modified crops has provided economic benefit to farmers in many different countries, but has also been the source of most of the controversy surrounding the technology. this has been present since its early use ; the first field trials were destroyed by anti - gm activists. although there is a scientific consensus that currently available food derived from gm crops poses no greater risk to human health than conventional food, critics consider gm food safety a leading concern. gene flow, impact on non - target organisms, control of the food supply and intellectual property rights have also been raised as potential issues. these concerns have led to the development of a regulatory framework, which started in 1975. it has led to an international treaty, the cartagena protocol on biosafety, that was adopted in 2000. individual countries have developed their own regulatory systems regarding gmos, with the most marked differences occurring between the the mid - 1900s. giving them such credit for their developments, most of their efforts were focused on designing the first digital computer. along with that, topics such as artificial intelligence began to be brought up as turing was beginning to question such technology of the time period. devices have been used to aid computation for thousands of years, probably initially in the form of a tally stick. the antikythera mechanism, dating from about the beginning of the first century bc, is generally considered the earliest known mechanical analog computer, and the earliest known geared mechanism. comparable geared devices did not emerge in europe until the 16th century, and it was not until 1645 that the first mechanical calculator capable of performing the four basic arithmetical operations was developed. electronic computers, using either relays or valves, began to appear in the early 1940s. the electromechanical zuse z3, completed in 1941, was the world ' s first programmable computer, and by modern standards one of the first machines that could be considered a complete computing machine. during the second world war, colossus developed the first electronic digital computer to decrypt german messages. although it was programmable, it was not general - purpose, being designed to perform only a single task. it also lacked the ability to store its program in memory ; programming was carried out using plugs and switches to alter the internal wiring. the first recognizably modern electronic digital stored - program computer was the manchester baby, which ran its first program on 21 june 1948. the development of transistors in the late 1940s at bell laboratories allowed a new generation of computers to be designed with greatly reduced power consumption. the first commercially available stored - program computer, the ferranti mark i, contained 4050 valves and had a power consumption of 25 kilowatts. by comparison, the first transistorized computer developed at the university of manchester and operational by november 1953, consumed only 150 watts in its final version. several other breakthroughs in semiconductor technology include the integrated circuit ( ic ) invented by jack kilby at texas instruments and robert noyce at fairchild semiconductor in 1959, silicon dioxide surface passivation by carl frosch and lincoln derick in 1955, the first planar silicon dioxide transistors by frosch and derick in 1957, the mosfet demonstration by a bell labs team, the planar process by jean hoerni in 1959, and the microprocessor invented by ted hoff, federico faggin, masatoshi shima, Question: What is first year after birth is called? A) infancy B) neonatal stage C) adolescence D) primary stage	A) infancy
Context: set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. = = = = substance and mixture = = = = a chemical substance is a kind of matter with a definite composition and set of properties. a collection of substances is called a mixture. examples of mixtures are air and alloys. = = = = mole and amount of substance = = = = the mole is a unit that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. = = = = substance and mixture = = = = a chemical substance is a kind of matter with a definite composition and set of properties. a collection of substances is called a mixture. examples of mixtures are air and alloys. = = = = mole and amount of substance = = = = the mole is a unit of measurement that denotes an amount of substance ( also called chemical amount ). one mole is defined to contain exactly 6. 02214076×1023 particles ( atoms, molecules, ions, or electrons ), where the number of particles per mole is known as the avogadro constant. molar concentration is polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of ( create a critical mass ) for detonation. it also is quite difficult to ensure that such a chain reaction consumes a significant fraction of the fuel before the device flies apart. the procurement of a nuclear fuel is also more difficult than it might seem, since sufficiently unstable substances for this process do not currently occur naturally on earth in suitable amounts. one isotope of uranium, namely uranium - 235, is naturally occurring and sufficiently unstable, but it is always found mixed with the more stable isotope uranium - 238. the latter accounts for more than 99 % of the weight of natural uranium. therefore, some method of isotope separation based on the weight of three neutrons must be performed to enrich ( isolate ) uranium - 235. alternatively, the element plutonium possesses an isotope that is sufficiently unstable for this process to be usable. terrestrial plutonium does not currently occur naturally in sufficient quantities for such use, so it must be manufactured in a nuclear reactor. ultimately, the manhattan project manufactured nuclear weapons based on each of these elements. they detonated the first nuclear weapon in a test code - named " trinity ", near alamogordo, new mexico, on july 16, 1945. the test was conducted to ensure that the implosion method of detonation would work, which it did. a uranium bomb, little boy, was dropped on the japanese city hiroshima on august 6, 1945, followed three days later by the plutonium - based fat man on nagasaki. in the wake of unprecedented devastation and casualties from a single weapon, the japanese government soon surrendered, ending world war ii. since these bombings, no nuclear weapons have been deployed offensively. nevertheless, they prompted an arms race to develop increasingly destructive bombs to provide a nuclear deterrent. just over four years later, on august 29, 1949, the soviet union detonated its first fission weapon. the united kingdom followed on october 2, 1952 ; france, on february 13, 1960 ; and china component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. a radiological weapon is a type of nuclear weapon designed to distribute hazardous nuclear material in enemy areas. such a weapon would not have the explosive capability of a fission or fusion bomb, but would kill many people and contaminate a large area. a radiological weapon has never been deployed. while considered useless by a conventional military, such a weapon raises concerns over nuclear terrorism. there have been over 2, 000 nuclear tests conducted since 1945. in 1963, all nuclear and many non - of measurement that denotes an amount of substance ( also called chemical amount ). one mole is defined to contain exactly 6. 02214076×1023 particles ( atoms, molecules, ions, or electrons ), where the number of particles per mole is known as the avogadro constant. molar concentration is the amount of a particular substance per volume of solution, and is commonly reported in mol / dm3. = = = phase = = = in addition to the specific chemical properties that distinguish different chemical classifications, chemicals can exist in several phases. for the most part, the chemical classifications are independent of these bulk phase classifications ; however, some more exotic phases are incompatible with certain chemical properties. a phase is a set of states of a chemical system that have similar bulk structural properties, over a range of conditions, such as pressure or temperature. physical properties, such as density and refractive index tend to fall within values characteristic of the phase. the phase of matter is defined by the phase transition, which is when energy put into or taken out of the system goes into rearranging the structure of the system, instead of changing the bulk conditions. sometimes the distinction between phases can be continuous instead of having a discrete boundary ; in this case the matter is considered to be in a supercritical state. when three states meet based on the conditions, it is known as a triple point and since this is invariant, it is a convenient way to define a set of conditions. the most familiar examples of phases are solids, liquids, and gases. many substances exhibit multiple solid phases. for example, there are three phases of solid iron ( alpha, gamma, and delta ) that vary based on temperature and pressure. a principal difference between solid phases is the crystal structure, or arrangement, of the atoms. another phase commonly encountered in the study of chemistry is the aqueous phase, which is the state of substances dissolved in aqueous solution ( that is, in water ). less familiar phases include plasmas, bose – einstein condensates and fermionic condensates and the paramagnetic and ferromagnetic phases of magnetic materials. while most familiar phases deal with three - dimensional systems, it is also possible to define analogs in two - dimensional systems, which has received attention for its relevance to systems in biology. = = = bonding = = = atoms sticking together in molecules or crystals are said to be bonded with one another. a chemical bond may be visualized as the multipole balance between the positive has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = the atom is the basic unit of chemistry. it consists of a dense core called the atomic nucleus surrounded by a space occupied by an electron cloud. the nucleus is made up of positively charged protons and uncharged neutrons ( together called nucleons ), while the electron cloud consists of negatively charged electrons which orbit the nucleus. in a neutral atom, the negatively charged electrons balance out the positive charge of the protons. the nucleus is dense ; the mass of a nucleon is approximately 1, 836 times that of an electron, yet the radius of an atom is about 10, 000 times that of its nucleus. the atom is also the smallest entity that can be envisaged to retain the chemical properties of the element, such as electronegativity, ionization potential, preferred oxidation state ( s ), coordination number, and preferred types of bonds to form ( e. g., metallic, ionic, covalent ). = = = = element = = = = a chemical element is a pure substance which is composed of a single type of atom, characterized by its particular number of protons in the nuclei of its atoms, known as the atomic number and represented by the symbol z. the mass number is the sum of the number of protons and neutrons in a nucleus. although all the nuclei of all atoms belonging to one element will have the same atomic number, they may not necessarily have the same mass number ; atoms of an element which have different mass numbers are known as isotopes. for example, all atoms with 6 protons in their nuclei are atoms of the chemical element carbon, but atoms of carbon may have mass numbers of 12 or 13. the standard presentation of the chemical elements is in the periodic table, which orders elements by atomic number. the periodic table is arranged in groups, or columns, and periods, or rows. the periodic table is useful in identifying periodic trends. = = = = compound = = = = a compound is a pure chemical substance composed of more than one element. the properties of a compound bear little similarity to those of its elements. the standard nomenclature of compounds is set by the international union of pure and applied chemistry ( iupac ). organic compounds are named index chemical substances. in this scheme each chemical substance is identifiable by a number known as its cas registry number. = = = = molecule = = = = a molecule is the smallest indivisible portion of a pure chemical substance that has its unique set of chemical properties, that is, its potential to undergo a certain set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry use less energy than conventional thermal separation processes such as distillation, sublimation or crystallization. the separation process is purely physical and both fractions ( permeate and retentate ) can be obtained as useful products. cold separation using membrane technology is widely used in the food technology, biotechnology and pharmaceutical industries. furthermore, using membranes enables separations to take place that would be impossible using thermal separation methods. for example, it is impossible to separate the constituents of azeotropic liquids or solutes which form isomorphic crystals by distillation or recrystallization but such separations can be achieved using membrane technology. depending on the type of membrane, the selective separation of certain individual substances or substance mixtures is possible. important technical applications include the production of drinking water by reverse osmosis. in waste water treatment, membrane technology is becoming increasingly important. ultra / microfiltration can be very effective in removing colloids and macromolecules from wastewater. this is needed if wastewater is discharged into sensitive waters especially those designated for contact water sports and recreation. about half of the market is in medical applications such as artificial kidneys to remove toxic substances by hemodialysis and as artificial lung for bubble - free supply of oxygen in the blood. the importance of membrane technology is growing in the field of environmental protection ( nano - mem - pro ippc database ). even in modern energy recovery techniques, membranes are increasingly used, for example in fuel cells and in osmotic power plants. = = mass transfer = = two basic models can be distinguished for mass transfer through the membrane : the solution - diffusion model and the hydrodynamic model. in real membranes, these two transport mechanisms certainly occur side by side, especially during ultra - filtration. = = = solution - diffusion model = = = in the solution - diffusion model, transport occurs only by diffusion. the component that needs to be transported must first be dissolved in the membrane. the general approach of the solution - diffusion model is to assume that the chemical potential of the feed and permeate fluids are in equilibrium with the adjacent membrane surfaces such that appropriate expressions for the chemical potential in the fluid and membrane phases can be equated at the solution - membrane interface. this principle is more important for dense membranes without natural pores such as those used for reverse osmosis and in fuel cells. during the filtration process a boundary layer forms on the membrane. this concentration gradient is created by molecules which cannot pass through the membrane. the Question: What do you call a substance that cannot be separated into smaller pieces, which is also defined by the number of protons it has? A) atom B) molecule C) element D) electrol	C) element
Context: applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales is a commonly used practice that helps better understand the metal ' s elasticity and plasticity for different applications and production processes. in a saltwater environment, most ferrous metals and some non - ferrous alloys corrode quickly. metals exposed to cold or cryogenic conditions may undergo a ductile to brittle transition and lose their toughness, becoming more brittle and prone to cracking. metals under continual cyclic loading can suffer from metal fatigue. metals under constant stress at elevated temperatures can creep. = = = metalworking processes = = = casting – molten metal is poured into a shaped mold. variants of casting include sand casting, investment the valuable metals into individual constituents. = = metal and its alloys = = much effort has been placed on understanding iron – carbon alloy system, which includes steels and cast irons. plain carbon steels ( those that contain essentially only carbon as an alloying element ) are used in low - cost, high - strength applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales is a commonly used practice that helps better understand the metal ' s elasticity and plasticity for different applications and production processes. in a saltwater environment, most ferrous metals and some non - ferrous alloys corrode quickly. metals exposed to cold or cryogenic conditions may undergo a ductile to brittle is collected and processed to extract valuable metals. ore bodies often contain more than one valuable metal. tailings of a previous process may be used as a feed in another process to extract a secondary product from the original ore. additionally, a concentrate may contain more than one valuable metal. that concentrate would then be processed to separate the valuable metals into individual constituents. = = metal and its alloys = = much effort has been placed on understanding iron – carbon alloy system, which includes steels and cast irons. plain carbon steels ( those that contain essentially only carbon as an alloying element ) are used in low - cost, high - strength applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales joints. = = = metal alloys = = = the alloys of iron ( steel, stainless steel, cast iron, tool steel, alloy steels ) make up the largest proportion of metals today both by quantity and commercial value. iron alloyed with various proportions of carbon gives low, mid and high carbon steels. an iron - carbon alloy is only considered steel if the carbon level is between 0. 01 % and 2. 00 % by weight. for steels, the hardness and tensile strength of the steel is related to the amount of carbon present, with increasing carbon levels also leading to lower ductility and toughness. heat treatment processes such as quenching and tempering can significantly change these properties, however. in contrast, certain metal alloys exhibit unique properties where their size and density remain unchanged across a range of temperatures. cast iron is defined as an iron – carbon alloy with more than 2. 00 %, but less than 6. 67 % carbon. stainless steel is defined as a regular steel alloy with greater than 10 % by weight alloying content of chromium. nickel and molybdenum are typically also added in stainless steels. other significant metallic alloys are those of aluminium, titanium, copper and magnesium. copper alloys have been known for a long time ( since the bronze age ), while the alloys of the other three metals have been relatively recently developed. due to the chemical reactivity of these metals, the electrolytic extraction processes required were only developed relatively recently. the alloys of aluminium, titanium and magnesium are also known and valued for their high strength to weight ratios and, in the case of magnesium, their ability to provide electromagnetic shielding. these materials are ideal for situations where high strength to weight ratios are more important than bulk cost, such as in the aerospace industry and certain automotive engineering applications. = = = semiconductors = = = a semiconductor is a material that has a resistivity between a conductor and insulator. modern day electronics run on semiconductors, and the industry had an estimated us $ 530 billion market in 2021. its electronic properties can be greatly altered through intentionally introducing impurities in a process referred to as doping. semiconductor materials are used to build diodes, transistors, light - emitting diodes ( leds ), and analog and digital electric circuits, among their many uses. semiconductor devices have replaced thermionic devices like vacuum tubes in most applications. semiconductor devices are manufactured both as single discrete devices and as integrated circuits ( ics ), which consist of a number — from a . historically, metallurgy has predominately focused on the production of metals. metal production begins with the processing of ores to extract the metal, and includes the mixture of metals to make alloys. metal alloys are often a blend of at least two different metallic elements. however, non - metallic elements are often added to alloys in order to achieve properties suitable for an application. the study of metal production is subdivided into ferrous metallurgy ( also known as black metallurgy ) and non - ferrous metallurgy, also known as colored metallurgy. ferrous metallurgy involves processes and alloys based on iron, while non - ferrous metallurgy involves processes and alloys based on other metals. the production of ferrous metals accounts for 95 % of world metal production. modern metallurgists work in both emerging and traditional areas as part of an interdisciplinary team alongside material scientists and other engineers. some traditional areas include mineral processing, metal production, heat treatment, failure analysis, and the joining of metals ( including welding, brazing, and soldering ). emerging areas for metallurgists include nanotechnology, superconductors, composites, biomedical materials, electronic materials ( semiconductors ) and surface engineering. = = etymology and pronunciation = = metallurgy derives from the ancient greek μεταλλουργος, metallourgos, " worker in metal ", from μεταλλον, metallon, " mine, metal " + εργον, ergon, " work " the word was originally an alchemist ' s term for the extraction of metals from minerals, the ending - urgy signifying a process, especially manufacturing : it was discussed in this sense in the 1797 encyclopædia britannica. in the late 19th century, metallurgy ' s definition was extended to the more general scientific study of metals, alloys, and related processes. in english, the pronunciation is the more common one in the united kingdom. the pronunciation is the more common one in the us and is the first - listed variant in various american dictionaries, including merriam - webster collegiate and american heritage. = = history = = the earliest metal employed by humans appears to be gold, which can be found " native ". small amounts of natural gold, dating to the late paleolithic period, 40, 000 bc, have been found in spanish caves. silver, copper, tin and meteoric iron iron - carbon alloy is only considered steel if the carbon level is between 0. 01 % and 2. 00 % by weight. for steels, the hardness and tensile strength of the steel is related to the amount of carbon present, with increasing carbon levels also leading to lower ductility and toughness. heat treatment processes such as quenching and tempering can significantly change these properties, however. in contrast, certain metal alloys exhibit unique properties where their size and density remain unchanged across a range of temperatures. cast iron is defined as an iron – carbon alloy with more than 2. 00 %, but less than 6. 67 % carbon. stainless steel is defined as a regular steel alloy with greater than 10 % by weight alloying content of chromium. nickel and molybdenum are typically also added in stainless steels. other significant metallic alloys are those of aluminium, titanium, copper and magnesium. copper alloys have been known for a long time ( since the bronze age ), while the alloys of the other three metals have been relatively recently developed. due to the chemical reactivity of these metals, the electrolytic extraction processes required were only developed relatively recently. the alloys of aluminium, titanium and magnesium are also known and valued for their high strength to weight ratios and, in the case of magnesium, their ability to provide electromagnetic shielding. these materials are ideal for situations where high strength to weight ratios are more important than bulk cost, such as in the aerospace industry and certain automotive engineering applications. = = = semiconductors = = = a semiconductor is a material that has a resistivity between a conductor and insulator. modern day electronics run on semiconductors, and the industry had an estimated us $ 530 billion market in 2021. its electronic properties can be greatly altered through intentionally introducing impurities in a process referred to as doping. semiconductor materials are used to build diodes, transistors, light - emitting diodes ( leds ), and analog and digital electric circuits, among their many uses. semiconductor devices have replaced thermionic devices like vacuum tubes in most applications. semiconductor devices are manufactured both as single discrete devices and as integrated circuits ( ics ), which consist of a number — from a few to millions — of devices manufactured and interconnected on a single semiconductor substrate. of all the semiconductors in use today, silicon makes up the largest portion both by quantity and commercial value. monocrystalline silicon is used to produce wafers used in the semiconductor and electronics industry. gallium arsenide ( is further subdivided into two broad categories : chemical metallurgy and physical metallurgy. chemical metallurgy is chiefly concerned with the reduction and oxidation of metals, and the chemical performance of metals. subjects of study in chemical metallurgy include mineral processing, the extraction of metals, thermodynamics, electrochemistry, and chemical degradation ( corrosion ). in contrast, physical metallurgy focuses on the mechanical properties of metals, the physical properties of metals, and the physical performance of metals. topics studied in physical metallurgy include crystallography, material characterization, mechanical metallurgy, phase transformations, and failure mechanisms. historically, metallurgy has predominately focused on the production of metals. metal production begins with the processing of ores to extract the metal, and includes the mixture of metals to make alloys. metal alloys are often a blend of at least two different metallic elements. however, non - metallic elements are often added to alloys in order to achieve properties suitable for an application. the study of metal production is subdivided into ferrous metallurgy ( also known as black metallurgy ) and non - ferrous metallurgy, also known as colored metallurgy. ferrous metallurgy involves processes and alloys based on iron, while non - ferrous metallurgy involves processes and alloys based on other metals. the production of ferrous metals accounts for 95 % of world metal production. modern metallurgists work in both emerging and traditional areas as part of an interdisciplinary team alongside material scientists and other engineers. some traditional areas include mineral processing, metal production, heat treatment, failure analysis, and the joining of metals ( including welding, brazing, and soldering ). emerging areas for metallurgists include nanotechnology, superconductors, composites, biomedical materials, electronic materials ( semiconductors ) and surface engineering. = = etymology and pronunciation = = metallurgy derives from the ancient greek μεταλλουργος, metallourgos, " worker in metal ", from μεταλλον, metallon, " mine, metal " + εργον, ergon, " work " the word was originally an alchemist ' s term for the extraction of metals from minerals, the ending - urgy signifying a process, especially manufacturing : it was discussed in this sense in the 1797 encyclopædia britannica. in the late 19th century, metallurgy ' in products for both consumers and manufacturers. metallurgy is distinct from the craft of metalworking. metalworking relies on metallurgy in a similar manner to how medicine relies on medical science for technical advancement. a specialist practitioner of metallurgy is known as a metallurgist. the science of metallurgy is further subdivided into two broad categories : chemical metallurgy and physical metallurgy. chemical metallurgy is chiefly concerned with the reduction and oxidation of metals, and the chemical performance of metals. subjects of study in chemical metallurgy include mineral processing, the extraction of metals, thermodynamics, electrochemistry, and chemical degradation ( corrosion ). in contrast, physical metallurgy focuses on the mechanical properties of metals, the physical properties of metals, and the physical performance of metals. topics studied in physical metallurgy include crystallography, material characterization, mechanical metallurgy, phase transformations, and failure mechanisms. historically, metallurgy has predominately focused on the production of metals. metal production begins with the processing of ores to extract the metal, and includes the mixture of metals to make alloys. metal alloys are often a blend of at least two different metallic elements. however, non - metallic elements are often added to alloys in order to achieve properties suitable for an application. the study of metal production is subdivided into ferrous metallurgy ( also known as black metallurgy ) and non - ferrous metallurgy, also known as colored metallurgy. ferrous metallurgy involves processes and alloys based on iron, while non - ferrous metallurgy involves processes and alloys based on other metals. the production of ferrous metals accounts for 95 % of world metal production. modern metallurgists work in both emerging and traditional areas as part of an interdisciplinary team alongside material scientists and other engineers. some traditional areas include mineral processing, metal production, heat treatment, failure analysis, and the joining of metals ( including welding, brazing, and soldering ). emerging areas for metallurgists include nanotechnology, superconductors, composites, biomedical materials, electronic materials ( semiconductors ) and surface engineering. = = etymology and pronunciation = = metallurgy derives from the ancient greek μεταλλουργος, metallourgos, " worker in metal ", from μεταλλον, metallon, " mine, metal " + εργον, ergon ##chemistry, and chemical degradation ( corrosion ). in contrast, physical metallurgy focuses on the mechanical properties of metals, the physical properties of metals, and the physical performance of metals. topics studied in physical metallurgy include crystallography, material characterization, mechanical metallurgy, phase transformations, and failure mechanisms. historically, metallurgy has predominately focused on the production of metals. metal production begins with the processing of ores to extract the metal, and includes the mixture of metals to make alloys. metal alloys are often a blend of at least two different metallic elements. however, non - metallic elements are often added to alloys in order to achieve properties suitable for an application. the study of metal production is subdivided into ferrous metallurgy ( also known as black metallurgy ) and non - ferrous metallurgy, also known as colored metallurgy. ferrous metallurgy involves processes and alloys based on iron, while non - ferrous metallurgy involves processes and alloys based on other metals. the production of ferrous metals accounts for 95 % of world metal production. modern metallurgists work in both emerging and traditional areas as part of an interdisciplinary team alongside material scientists and other engineers. some traditional areas include mineral processing, metal production, heat treatment, failure analysis, and the joining of metals ( including welding, brazing, and soldering ). emerging areas for metallurgists include nanotechnology, superconductors, composites, biomedical materials, electronic materials ( semiconductors ) and surface engineering. = = etymology and pronunciation = = metallurgy derives from the ancient greek μεταλλουργος, metallourgos, " worker in metal ", from μεταλλον, metallon, " mine, metal " + εργον, ergon, " work " the word was originally an alchemist ' s term for the extraction of metals from minerals, the ending - urgy signifying a process, especially manufacturing : it was discussed in this sense in the 1797 encyclopædia britannica. in the late 19th century, metallurgy ' s definition was extended to the more general scientific study of metals, alloys, and related processes. in english, the pronunciation is the more common one in the united kingdom. the pronunciation is the more common one in the us and is the first - listed variant in various american dictionaries, including merriam - webster collegiate surface. ceramics such as alumina, boron carbide and silicon carbide have been used in bulletproof vests to repel small arms rifle fire. such plates are known commonly as ballistic plates. similar material is used to protect cockpits of some military aircraft, because of the low weight of the material. silicon nitride parts are used in ceramic ball bearings. their higher hardness means that they are much less susceptible to wear and can offer more than triple lifetimes. they also deform less under load meaning they have less contact with the bearing retainer walls and can roll faster. in very high speed applications, heat from friction during rolling can cause problems for metal bearings ; problems which are reduced by the use of ceramics. ceramics are also more chemically resistant and can be used in wet environments where steel bearings would rust. the major drawback to using ceramics is a significantly higher cost. in many cases their electrically insulating properties may also be valuable in bearings. in the early 1980s, toyota researched production of an adiabatic ceramic engine which can run at a temperature of over 6000 °f ( 3300 °c ). ceramic engines do not require a cooling system and hence allow a major weight reduction and therefore greater fuel efficiency. fuel efficiency of the engine is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or Question: A protective coating of zinc to prevent corrosion is applied to steel and other metals labeled what? A) corroded B) polarized C) battered D) galvanized	D) galvanized
Context: ##yotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. in plants the dna is often inserted using agrobacterium - mediated transformation, taking advantage of the agrobacteriums t - dna sequence that allows natural insertion of genetic material into plant cells. other methods include biolistics, where particles of gold or tungsten are coated with dna and then shot into young plant cells, and electroporation, which involves using an electric shock to make the cell membrane permeable to plasmid dna. as only a single cell is transformed with genetic material, the organism must be regenerated from that single cell. in plants this is accomplished through the use of tissue culture. in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes of homologous recombination and nonhomologous end - joining. there are four families of engineered nucleases : meganucleases, zinc finger nucleases, transcription activator - like effector nucleases ( talens ), and the cas9 - guide , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection process of lactic acid fermentation, which produced other preserved foods, such as soy sauce. fermentation was also used in this time period to produce leavened bread. although the process of fermentation was not fully understood until louis pasteur ' s work in 1857, it is still the first use of biotechnology to convert a food source into another form. before the time of charles darwin ' s work and life, animal and plant scientists had already used selective breeding. darwin added to that body of work with his scientific observations about the ability of science to change species. these accounts contributed to darwin ' s theory of natural selection. for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united kingdom desperately needed to manufacture explosives during world war i. biotechnology has also led to the development of antibiotics. in 1928, alexander fleming discovered the mold penicillium. his work led to the purification of the antibiotic formed by the mold by howard florey, ernst boris chain and norman heatley – to form what we today know as penicillin. in 1940, penicillin became available for medicinal use to treat bacterial infections in humans. the field of modern biotechnology is generally thought of as having been born in 1971 when paul berg ' s ( stanford ) experiments in gene splicing had early success. herbert w. boyer ( univ. calif. at san francisco ) and stanley n. cohen ( stanford ) significantly advanced the new technology in 1972 by transferring genetic material into a bacterium, such that the imported material would be reproduced. the commercial viability of a biotechnology industry was significantly expanded on june 16, 1980, when the united states supreme court ruled that a genetically modified microorganism could be patented in the case of diamond v. chakrabarty. indian - born ananda chakrabarty, working for general electric, had modified a bacterium ( of the genus pseudomonas ) capable of breaking down crude oil, which he proposed to urinary tract infection ( utis ) is referred as one of the most common infection in medical sectors worldwide and antimicrobial resistance ( amr ) is also a global threat to human that is related with many diseases. as antibiotics used for the treatment of infectious diseases, the rate of resistance is increasing day by day. gram positive pathogens are commonly found in urine sample collected from different age groups of people, associated with uti. the study was conducted in a diagnostic center in dhaka, bangladesh with total 1308 urine samples from november 2021 to april 2022. gram positive pathogens were isolated and antimicrobial susceptibility tests were done. from total 121 samples of gram positive bacteria the highest prevalence rate of utis was found in age group of 21 - 30 year. mostly enterococcus spp. ( 33. 05 % ) staphylococcus aureus ( 27. 27 % ), streptococcus spp. ( 20. 66 % ), beta - hemolytic streptococci ( 19. 00 % ) were found as causative agents of uti compared to others. the majority of isolates have been detected as multi - drug resistant ( mdr ). the higher percentage of antibiotic resistance were found against azithromycin ( 75 % ), and cefixime ( 64. 46 % ). this research focused on the regular basis of surveillance for the gram - positive bacteria antibiotic susceptibility to increase awareness about the use of proper antibiotic thus minimize the drug resistance. consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea. more than 6, 000 virus species have been described in detail. viruses are found in almost every ecosystem on earth and are the most numerous type of biological entity. the origins of viruses in the evolutionary history of life are unclear : some may have evolved from plasmids — pieces of dna that can move between cells — while others may have evolved from bacteria. in evolution, viruses are an important means of horizontal gene transfer, which increases genetic diversity in a way analogous to sexual reproduction. because viruses possess some but not all characteristics of life, they have been described as " organisms at the edge of life ", and as self - replicators. = = ecology = = ecology is the study of the distribution and abundance of life, the interaction between organisms and their environment. = = = ecosystems = = = the community of living ( biotic ) organisms in conjunction with the nonliving ( abiotic ) components ( e. g., water, light, radiation, temperature, humidity, atmosphere, acidity, and soil ) of their environment is called an ecosystem. these biotic and abiotic components are linked together through nutrient cycles and energy flows. energy from the sun enters the system through photosynthesis and is incorporated into plant tissue. by feeding on plants and on one another, animals move matter and energy through the system. they also influence the quantity of plant and microbial biomass present. by breaking down dead organic matter, decomposers release carbon back to the atmosphere and facilitate nutrient cycling by converting nutrients stored in dead biomass back to a form that can be readily used by plants and other microbes. = = = populations = = = a population is the group of organisms of the same species that occupies an area and reproduce from generation to generation. population size can be estimated by multiplying population density by the area or volume. the carrying capacity of an environment for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united kingdom desperately needed to manufacture explosives during world war i. biotechnology has also led to the development of antibiotics. in 1928, alexander fleming discovered the mold penicillium. his work led to the purification of the antibiotic formed by the mold by howard florey, ernst boris chain and norman heatley – to form what we today know as penicillin. in 1940, penicillin became available for medicinal use to treat bacterial infections in humans. the field of modern biotechnology is generally thought of as having been born in 1971 when paul berg ' s ( stanford ) experiments in gene splicing had early success. herbert w. boyer ( univ. calif. at san francisco ) and stanley n. cohen ( stanford ) significantly advanced the new technology in 1972 by transferring genetic material into a bacterium, such that the imported material would be reproduced. the commercial viability of a biotechnology industry was significantly expanded on june 16, 1980, when the united states supreme court ruled that a genetically modified microorganism could be patented in the case of diamond v. chakrabarty. indian - born ananda chakrabarty, working for general electric, had modified a bacterium ( of the genus pseudomonas ) capable of breaking down crude oil, which he proposed to use in treating oil spills. ( chakrabarty ' s work did not involve gene manipulation but rather the transfer of entire organelles between strains of the pseudomonas bacterium ). the mosfet invented at bell labs between 1955 and 1960, two years later, leland c. clark and champ lyons invented the first biosensor in 1962. biosensor mosfets were later developed, and they have since been widely used to measure physical, chemical, biological and environmental parameters. the first biofet was the ion - sensitive field - effect transistor ( isfet ), invented by piet bergveld is opened and the dna is purified. the gene is separated by using restriction enzymes to cut the dna into fragments or polymerase chain reaction ( pcr ) to amplify up the gene segment. these segments can then be extracted through gel electrophoresis. if the chosen gene or the donor organism ' s genome has been well studied it may already be accessible from a genetic library. if the dna sequence is known, but no copies of the gene are available, it can also be artificially synthesised. once isolated the gene is ligated into a plasmid that is then inserted into a bacterium. the plasmid is replicated when the bacteria divide, ensuring unlimited copies of the gene are available. the rk2 plasmid is notable for its ability to replicate in a wide variety of single - celled organisms, which makes it suitable as a genetic engineering tool. before the gene is inserted into the target organism it must be combined with other genetic elements. these include a promoter and terminator region, which initiate and end transcription. a selectable marker gene is added, which in most cases confers antibiotic resistance, so researchers can easily determine which cells have been successfully transformed. the gene can also be modified at this stage for better expression or effectiveness. these manipulations are carried out using recombinant dna techniques, such as restriction digests, ligations and molecular cloning. = = = inserting dna into the host genome = = = there are a number of techniques used to insert genetic material into the host genome. some bacteria can naturally take up foreign dna. this ability can be induced in other bacteria via stress ( e. g. thermal or electric shock ), which increases the cell membrane ' s permeability to dna ; up - taken dna can either integrate with the genome or exist as extrachromosomal dna. dna is generally inserted into animal cells using microinjection, where it can be injected through the cell ' s nuclear envelope directly into the nucleus, or through the use of viral vectors. plant genomes can be engineered by physical methods or by use of agrobacterium for the delivery of sequences hosted in t - dna binary vectors. in plants the dna is often inserted using agrobacterium - mediated transformation, taking advantage of the agrobacteriums t - dna sequence that allows natural insertion of genetic material into plant cells. other methods include biolistics, where particles of gold or tungsten are coated with dna and then shot into for natural scientists, with the creation of transgenic organisms one of the most important tools for analysis of gene function. genes and other genetic information from a wide range of organisms can be inserted into bacteria for storage and modification, creating genetically modified bacteria in the process. bacteria are cheap, easy to grow, clonal, multiply quickly, relatively easy to transform and can be stored at - 80 °c almost indefinitely. once a gene is isolated it can be stored inside the bacteria providing an unlimited supply for research. organisms are genetically engineered to discover the functions of certain genes. this could be the effect on the phenotype of the organism, where the gene is expressed or what other genes it interacts with. these experiments generally involve loss of function, gain of function, tracking and expression. loss of function experiments, such as in a gene knockout experiment, in which an organism is engineered to lack the activity of one or more genes. in a simple knockout a copy of the desired gene has been altered to make it non - functional. embryonic stem cells incorporate the altered gene, which replaces the already present functional copy. these stem cells are injected into blastocysts, which are implanted into surrogate mothers. this allows the experimenter to analyse the defects caused by this mutation and thereby determine the role of particular genes. it is used especially frequently in developmental biology. when this is done by creating a library of genes with point mutations at every position in the area of interest, or even every position in the whole gene, this is called " scanning mutagenesis ". the simplest method, and the first to be used, is " alanine scanning ", where every position in turn is mutated to the unreactive amino acid alanine. gain of function experiments, the logical counterpart of knockouts. these are sometimes performed in conjunction with knockout experiments to more finely establish the function of the desired gene. the process is much the same as that in knockout engineering, except that the construct is designed to increase the function of the gene, usually by providing extra copies of the gene or inducing synthesis of the protein more frequently. gain of function is used to tell whether or not a protein is sufficient for a function, but does not always mean it is required, especially when dealing with genetic or functional redundancy. tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. one way to do this is to replace the wild - type gene with a ' fusion ' gene, which is a juxtaposition Question: How do bacteria reproduce? A) budding B) nuclear fission C) binary fission D) sexual reproduction	C) binary fission
Context: cortisol, corticosterone and aldosterone activate full - length glucocorticoid receptor ( gr ) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. activation by aldosterone a mineralocorticoid, indicates partial divergence of elephant shark gr from the mr. progesterone activates elephant shark mr, but not elephant shark gr. progesterone inhibits steroid binding to elephant shark gr, but not to human gr. deletion of the n - terminal domain ( ntd ) from elephant shark gr ( truncated gr ) reduced the response to corticosteroids, while truncated and full - length elephant shark mr had similar responses to corticosteroids. chimeras of elephant shark gr ntd fused to mr dbd + lbd had increased activation by corticosteroids and progesterone compared to full - length elephant shark mr. elephant shark mr ntd fused to gr dbd + lbd had similar activation as full - length elephant shark mr, indicating that activation of human gr by the ntd evolved early in gr divergence from the mr. defective body parts. inside the body, artificial heart valves are in common use with artificial hearts and lungs seeing less common use but under active technology development. other medical devices and aids that can be considered prosthetics include hearing aids, artificial eyes, palatal obturator, gastric bands, and dentures. prostheses are specifically not orthoses, although given certain circumstances a prosthesis might end up performing some or all of the same functionary benefits as an orthosis. prostheses are technically the complete finished item. for instance, a c - leg knee alone is not a prosthesis, but only a prosthetic component. the complete prosthesis would consist of the attachment system to the residual limb – usually a " socket ", and all the attachment hardware components all the way down to and including the terminal device. despite the technical difference, the terms are often used interchangeably. the terms " prosthetic " and " orthotic " are adjectives used to describe devices such as a prosthetic knee. the terms " prosthetics " and " orthotics " are used to describe the respective allied health fields. an occupational therapist ' s role in prosthetics include therapy, training and evaluations. prosthetic training includes orientation to prosthetics components and terminology, donning and doffing, wearing schedule, and how to care for residual limb and the prosthesis. = = = exoskeletons = = = a powered exoskeleton is a wearable mobile machine that is powered by a system of electric motors, pneumatics, levers, hydraulics, or a combination of technologies that allow for limb movement with increased strength and endurance. its design aims to provide back support, sense the user ' s motion, and send a signal to motors which manage the gears. the exoskeleton supports the shoulder, waist and thigh, and assists movement for lifting and holding heavy items, while lowering back stress. = = = adaptive seating and positioning = = = people with balance and motor function challenges often need specialized equipment to sit or stand safely and securely. this equipment is frequently specialized for specific settings such as in a classroom or nursing home. positioning is often important in seating arrangements to ensure that user ' s body pressure is distributed equally without inhibiting movement in a desired way. positioning devices have been developed to aid in allowing people to stand and bear weight on their legs without risk of a fall. beam reveals the object ' s location. since radio waves travel at a constant speed close to the speed of light, by measuring the brief time delay between the outgoing pulse and the received " echo ", the range to the target can be calculated. the targets are often displayed graphically on a map display called a radar screen. doppler radar can measure a moving object ' s velocity, by measuring the change in frequency of the return radio waves due to the doppler effect. radar sets mainly use high frequencies in the microwave bands, because these frequencies create strong reflections from objects the size of vehicles and can be focused into narrow beams with compact antennas. parabolic ( dish ) antennas are widely used. in most radars the transmitting antenna also serves as the receiving antenna ; this is called a monostatic radar. a radar which uses separate transmitting and receiving antennas is called a bistatic radar. airport surveillance radar – in aviation, radar is the main tool of air traffic control. a rotating dish antenna sweeps a vertical fan - shaped beam of microwaves around the airspace and the radar set shows the location of aircraft as " blips " of light on a display called a radar screen. airport radar operates at 2. 7 – 2. 9 ghz in the microwave s band. in large airports the radar image is displayed on multiple screens in an operations room called the tracon ( terminal radar approach control ), where air traffic controllers direct the aircraft by radio to maintain safe aircraft separation. secondary surveillance radar – aircraft carry radar transponders, transceivers which when triggered by the incoming radar signal transmit a return microwave signal. this causes the aircraft to show up more strongly on the radar screen. the radar which triggers the transponder and receives the return beam, usually mounted on top of the primary radar dish, is called the secondary surveillance radar. since radar cannot measure an aircraft ' s altitude with any accuracy, the transponder also transmits back the aircraft ' s altitude measured by its altimeter, and an id number identifying the aircraft, which is displayed on the radar screen. electronic countermeasures ( ecm ) – military defensive electronic systems designed to degrade enemy radar effectiveness, or deceive it with false information, to prevent enemies from locating local forces. it often consists of powerful microwave transmitters that can mimic enemy radar signals to create false target indications on the enemy radar screens. marine radar – an s or x band radar on ships used to detect nearby ships and obstructions like bridges. a rotating antenna sweeps a vertical index chemical substances. in this scheme each chemical substance is identifiable by a number known as its cas registry number. = = = = molecule = = = = a molecule is the smallest indivisible portion of a pure chemical substance that has its unique set of chemical properties, that is, its potential to undergo a certain set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry trauma, reconstruction of the facial features using remains of deceased ( skull ) thus aiding identification. gender - based medicine studies the biological and physiological differences between the human sexes and how that affects differences in disease. health informatics is a relatively recent field that deal with the application of computers and information technology to medicine. hospice and palliative medicine is a relatively modern branch of clinical medicine that deals with pain and symptom relief and emotional support in patients with terminal illnesses including cancer and heart failure. hospital medicine is the general medical care of hospitalized patients. physicians whose primary professional focus is hospital medicine are called hospitalists in the united states and canada. the term most responsible physician ( mrp ) or attending physician is also used interchangeably to describe this role. laser medicine involves the use of lasers in the diagnostics or treatment of various conditions. many other health science fields, e. g. dietetics medical ethics deals with ethical and moral principles that apply values and judgments to the practice of medicine. medical humanities includes the humanities ( literature, philosophy, ethics, history and religion ), social science ( anthropology, cultural studies, psychology, sociology ), and the arts ( literature, theater, film, and visual arts ) and their application to medical education and practice. nosokinetics is the science / subject of measuring and modelling the process of care in health and social care systems. nosology is the classification of diseases for various purposes. occupational medicine is the provision of health advice to organizations and individuals to ensure that the highest standards of health and safety at work can be achieved and maintained. pain management ( also called pain medicine, or algiatry ) is the medical discipline concerned with the relief of pain. pharmacogenomics is a form of individualized medicine. podiatric medicine is the study of, diagnosis, and medical treatment of disorders of the foot, ankle, lower limb, hip and lower back. sexual medicine is concerned with diagnosing, assessing and treating all disorders related to sexuality. sports medicine deals with the treatment and prevention and rehabilitation of sports / exercise injuries such as muscle spasms, muscle tears, injuries to ligaments ( ligament tears or ruptures ) and their repair in athletes, amateur and professional. therapeutics is the field, more commonly referenced in earlier periods of history, of the various remedies that can be used to treat disease and promote health. travel medicine or emporiatrics deals with health problems of international travelers or travelers across highly different environments. tropical medicine deals with the prevention and treatment of tropical diseases interventions lacked sufficient evidence to support either benefit or harm. in modern clinical practice, physicians and physician assistants personally assess patients to diagnose, prognose, treat, and prevent disease using clinical judgment. the doctor - patient relationship typically begins with an interaction with an examination of the patient ' s medical history and medical record, followed by a medical interview and a physical examination. basic diagnostic medical devices ( e. g., stethoscope, tongue depressor ) are typically used. after examining for signs and interviewing for symptoms, the doctor may order medical tests ( e. g., blood tests ), take a biopsy, or prescribe pharmaceutical drugs or other therapies. differential diagnosis methods help to rule out conditions based on the information provided. during the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. the medical encounter is then documented in the medical record, which is a legal document in many jurisdictions. follow - ups may be shorter but follow the same general procedure, and specialists follow a similar process. the diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue. the components of the medical interview and encounter are : chief complaint ( cc ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have teeth. forensic optometry is the study of glasses and other eyewear relating to crime scenes and criminal investigations. forensic pathology is a field in which the principles of medicine and pathology are applied to determine a cause of death or injury in the context of a legal inquiry. forensic podiatry is an application of the study of feet footprint or footwear and their traces to analyze scene of crime and to establish personal identity in forensic examinations. forensic psychiatry is a specialized branch of psychiatry as applied to and based on scientific criminology. forensic psychology is the study of the mind of an individual, using forensic methods. usually it determines the circumstances behind a criminal ' s behavior. forensic seismology is the study of techniques to distinguish the seismic signals generated by underground nuclear explosions from those generated by earthquakes. forensic serology is the study of the body fluids. forensic social work is the specialist study of social work theories and their applications to a clinical, criminal justice or psychiatric setting. practitioners of forensic social work connected with the criminal justice system are often termed social supervisors, whilst the remaining use the interchangeable titles forensic social worker, approved mental health professional or forensic practitioner and they conduct specialist assessments of risk, care planning and act as an officer of the court. forensic toxicology is the study of the effect of drugs and poisons on / in the human body. forensic video analysis is the scientific examination, comparison and evaluation of video in legal matters. mobile device forensics is the scientific examination and evaluation of evidence found in mobile phones, e. g. call history and deleted sms, and includes sim card forensics. trace evidence analysis is the analysis and comparison of trace evidence including glass, paint, fibres and hair ( e. g., using micro - spectrophotometry ). wildlife forensic science applies a range of scientific disciplines to legal cases involving non - human biological evidence, to solve crimes such as poaching, animal abuse, and trade in endangered species. = = questionable techniques = = some forensic techniques, believed to be scientifically sound at the time they were used, have turned out later to have much less scientific merit or none. some such techniques include : comparative bullet - lead analysis was used by the fbi for over four decades, starting with the john f. kennedy assassination in 1963. the theory was that each batch of ammunition possessed a chemical makeup so distinct that a bullet could be traced back to a particular batch or even a specific box. internal studies and an outside study by the national academy of sciences found that the technique was unreliable due to like it, assist physical therapists by providing task - specific practice of walking in people following neurological injury. = = = prosthesis = = = a prosthesis, prosthetic, or prosthetic limb is a device that replaces a missing body part. it is part of the field of biomechatronics, the science of using mechanical devices with human muscular, musculoskeletal, and nervous systems to assist or enhance motor control lost by trauma, disease, or defect. prostheses are typically used to replace parts lost by injury ( traumatic ) or missing from birth ( congenital ) or to supplement defective body parts. inside the body, artificial heart valves are in common use with artificial hearts and lungs seeing less common use but under active technology development. other medical devices and aids that can be considered prosthetics include hearing aids, artificial eyes, palatal obturator, gastric bands, and dentures. prostheses are specifically not orthoses, although given certain circumstances a prosthesis might end up performing some or all of the same functionary benefits as an orthosis. prostheses are technically the complete finished item. for instance, a c - leg knee alone is not a prosthesis, but only a prosthetic component. the complete prosthesis would consist of the attachment system to the residual limb – usually a " socket ", and all the attachment hardware components all the way down to and including the terminal device. despite the technical difference, the terms are often used interchangeably. the terms " prosthetic " and " orthotic " are adjectives used to describe devices such as a prosthetic knee. the terms " prosthetics " and " orthotics " are used to describe the respective allied health fields. an occupational therapist ' s role in prosthetics include therapy, training and evaluations. prosthetic training includes orientation to prosthetics components and terminology, donning and doffing, wearing schedule, and how to care for residual limb and the prosthesis. = = = exoskeletons = = = a powered exoskeleton is a wearable mobile machine that is powered by a system of electric motors, pneumatics, levers, hydraulics, or a combination of technologies that allow for limb movement with increased strength and endurance. its design aims to provide back support, sense the user ' s motion, and send a signal to motors which manage the a minimum atmospheric temperature, or tropopause, occurs at a pressure of around 0. 1 bar in the atmospheres of earth, titan, jupiter, saturn, uranus and neptune, despite great differences in atmospheric composition, gravity, internal heat and sunlight. in all these bodies, the tropopause separates a stratosphere with a temperature profile that is controlled by the absorption of shortwave solar radiation, from a region below characterised by convection, weather, and clouds. however, it is not obvious why the tropopause occurs at the specific pressure near 0. 1 bar. here we use a physically - based model to demonstrate that, at atmospheric pressures lower than 0. 1 bar, transparency to thermal radiation allows shortwave heating to dominate, creating a stratosphere. at higher pressures, atmospheres become opaque to thermal radiation, causing temperatures to increase with depth and convection to ensue. a common dependence of infrared opacity on pressure, arising from the shared physics of molecular absorption, sets the 0. 1 bar tropopause. we hypothesize that a tropopause at a pressure of approximately 0. 1 bar is characteristic of many thick atmospheres, including exoplanets and exomoons in our galaxy and beyond. judicious use of this rule could help constrain the atmospheric structure, and thus the surface environments and habitability, of exoplanets. layer of the skin. these wearables are mounted directly onto the skin to continuously monitor physiological and metabolic processes, both dermal and subdermal. wireless capability is typically achieved through battery, bluetooth or nfc, making these devices convenient and portable as a type of wearable technology. currently, epidermal electronics are being developed in the fields of fitness and medical monitoring. current usage of epidermal technology is limited by existing fabrication processes. its current application relies on various sophisticated fabrication techniques such as by lithography or by directly printing on a carrier substrate before attaching directly to the body. research into printing epidermal electronics directly on the skin is currently available as a sole study source. the significance of epidermal electronics involves their mechanical properties, which resemble those of skin. the skin can be modeled as bilayer, composed of an epidermis having young ' s modulus ( e ) of 2 - 80 kpa and thickness of 0. 3 – 3 mm and a dermis having e of 140 - 600 kpa and thickness of 0. 05 - 1. 5 mm. together this bilayer responds plastically to tensile strains ≥ 30 %, below which the skin ' s surface stretches and wrinkles without deforming. properties of epidermal electronics mirror those of skin to allow them to perform in this same way. like skin, epidermal electronics are ultrathin ( h < 100 μm ), low - modulus ( e ≈70 kpa ), and lightweight ( < 10 mg / cm2 ), enabling them to conform to the skin without applying strain. conformal contact and proper adhesion enable the device to bend and stretch without delaminating, deforming or failing, thereby eliminating the challenges with conventional, bulky wearables, including measurement artifacts, hysteresis, and motion - induced irritation to the skin. with this inherent ability to take the shape of skin, epidermal electronics can accurately acquire data without altering the natural motion or behavior of skin. the thin, soft, flexible design of epidermal electronics resembles that of temporary tattoos laminated on the skin. essentially, these devices are " mechanically invisible " to the wearer. epidermal electronics devices may adhere to the skin via van der waals forces or elastomeric substrates. with only van der waals forces, an epidermal device has the same thermal mass per unit area ( 150 mj / cm2k ) as skin, when the skin ' s thickness is < 500 Question: The pituitary gland is associated with what bodily system? A) digestive B) endocrine C) nervous D) cardiovascular	B) endocrine
Context: their mechanical properties. = = tissue culture = = in many cases, creation of functional tissues and biological structures in vitro requires extensive culturing to promote survival, growth and inducement of functionality. in general, the basic requirements of cells must be maintained in culture, which include oxygen, ph, humidity, temperature, nutrients and osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively in future clinical stem cell therapies. mc2 biotek has also developed a bioreactor known as prototissue that uses gas exchange to maintain high oxygen levels within the cell chamber ; improving upon previous bioreactors, since the higher oxygen levels help the cell grow and undergo normal cell respiration. active there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively in future clinical stem cell therapies. mc2 biotek has also developed a bioreactor known as prototissue that uses gas exchange to maintain high oxygen levels within the cell chamber ; improving upon previous bioreactors, since the higher oxygen levels help the cell grow and undergo normal cell respiration. active areas of research on bioreactors includes increasing production scale and refining the physiological environment, both of which could improve the efficiency and efficacy of bioreactors in research or clinical use. bioreactors are currently used to study, among other things, cell and tissue level therapies, cell and tissue response to specific physiological environment changes, and development of disease and injury. = = = long fiber generation = = = in 2013, a group from the university of tokyo developed cell laden fibers up to a meter in length and on the order of 100 μm in size. these fibers were created using a microfluidic device that forms a kidneys and the majority of those currently in use are extracorporeal, such as with hemodialysis, which filters blood directly, or peritoneal dialysis, which filters via a fluid in the abdomen. in order to contribute to the biological functions of a kidney such as producing metabolic factors or hormones, some artificial kidneys incorporate renal cells. there has been progress in the way of making these devices smaller and more transportable, or even implantable. one challenge still to be faced in these smaller devices is countering the limited volume and therefore limited filtering capabilities. bioscaffolds have also been introduced to provide a framework upon which normal kidney tissue can be regenerated. these scaffolds encompass natural scaffolds ( e. g., decellularized kidneys, collagen hydrogel, or silk fibroin ), synthetic scaffolds ( e. g., poly [ lactic - co - glycolic acid ] or other polymers ), or a combination of two or more natural and synthetic scaffolds. these scaffolds can be implanted into the body either without cell treatment or after a period of stem cell seeding and incubation. in vitro and in vivo studies are being conducted to compare and optimize the type of scaffold and to assess whether cell seeding prior to implantation adds to the viability, regeneration and effective function of the kidneys. a recent systematic review and meta - analysis compared the results of published animal studies and identified that improved outcomes are reported with the use of hybrid ( mixed ) scaffolds and cell seeding ; however, the meta - analysis of these results were not in agreement with the evaluation of descriptive results from the review. therefore, further studies involving larger animals and novel scaffolds, and more transparent reproduction of previous studies are advisable. = = = biomimetics = = = biomimetics is a field that aims to produce materials and systems that replicate those present in nature. in the context of tissue engineering, this is a common approach used by engineers to create materials for these applications that are comparable to native tissues in terms of their structure, properties, and biocompatibility. material properties are largely dependent on physical, structural, and chemical characteristics of that material. subsequently, a biomimetic approach to system design will become significant in material integration, and a sufficient understanding of biological processes and interactions will be necessary. replication of biological systems and blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of while co - coculturing epithelial and adipocyte cells. the hystem kit is another 3 - d platform containing ecm components and hyaluronic acid that has been used for cancer research. additionally, hydrogel constituents can be chemically modified to assist in crosslinking and enhance their mechanical properties. = = tissue culture = = in many cases, creation of functional tissues and biological structures in vitro requires extensive culturing to promote survival, growth and inducement of functionality. in general, the basic requirements of cells must be maintained in culture, which include oxygen, ph, humidity, temperature, nutrients and osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively in future clinical stem cell therapies. mc2 biotek has also developed a bioreactor known as prototissue that uses gas exchange to maintain high oxygen levels within the cell chamber ; improving upon previous bioreactors, since the higher oxygen levels help the cell grow and undergo normal cell respiration. active areas of research on bioreactors includes increasing production scale and refining the physiological environment, both of which could improve the efficiency and efficacy of bioreactors in research or clinical use. bioreactors are currently used to study, among other things, cell and tissue level therapies, cell and tissue response to specific physiological the following purposes : allowing cell attachment and migration, delivering and retaining cells and biochemical factors, enabling diffusion of vital cell nutrients and expressed products, and exerting certain mechanical and biological influences to modify the behaviour of the cell phase. in 2009, an interdisciplinary team led by the thoracic surgeon thorsten walles implanted the first bioartificial transplant that provides an innate vascular network for post - transplant graft supply successfully into a patient awaiting tracheal reconstruction. to achieve the goal of tissue reconstruction, scaffolds must meet some specific requirements. high porosity and adequate pore size are necessary to facilitate cell seeding and diffusion throughout the whole structure of both cells and nutrients. biodegradability is often an essential factor since scaffolds should preferably be absorbed by the surrounding tissues without the necessity of surgical removal. the rate at which degradation occurs has to coincide as much as possible with the rate of tissue formation : this means that while cells are fabricating their own natural matrix structure around themselves, the scaffold is able to provide structural integrity within the body and eventually it will break down leaving the newly formed tissue which will take over the mechanical load. injectability is also important for clinical uses. recent research on organ printing is showing how crucial a good control of the 3d environment is to ensure reproducibility of experiments and offer better results. = = = materials = = = material selection is an essential aspect of producing a scaffold. the materials utilized can be natural or synthetic and can be biodegradable or non - biodegradable. additionally, they must be biocompatible, meaning that they do not cause any adverse effects to cells. silicone, for example, is a synthetic, non - biodegradable material commonly used as a drug delivery material, while gelatin is a biodegradable, natural material commonly used in cell - culture scaffolds the material needed for each application is different, and dependent on the desired mechanical properties of the material. tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone ( 100 - 150 mpa ), which is much higher compared to a scaffold for skin regeneration. there are a few versatile synthetic materials used for many different scaffold applications. one of these commonly used materials is polylactic acid ( pla ), a synthetic polymer. pla – polylactic acid. this is a polyester which Question: Why is it necessary to maintain proper levels of cations in intercellular fluids? A) keep cells healthy B) for digestion C) cell division D) reverse homeostasis	A) keep cells healthy
Context: , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became . microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of ##rozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokar they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off ##ochondria and chloroplasts, both of which are now part of modern - day eukaryotic cells. the major lineages of eukaryotes diversified in the precambrian about 1. 5 billion years ago and can be classified into eight major clades : alveolates, excavates, stramenopiles, plants, rhizarians, amoebozoans, fungi, and animals. five of these clades are collectively known as protists, which are mostly microscopic eukaryotic organisms that are not plants, fungi, or animals. while it is likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, invertebrates, or protozoans, the protist grouping is not a formal taxonomic group but is used for convenience. most protists are unicellular ; these are called microbial eukaryotes. plants are mainly multicellular organisms, predominantly photosynthetic eukaryotes of the kingdom plantae, which would exclude fungi and some algae. plant cells were derived by endosymbiosis of a cyanobacterium into an early eukaryote about one billion years ago, which gave rise to chloroplasts. the first several clades that emerged following primary endosymbiosis were aquatic and most of the aquatic photosynthetic eukaryotic organisms are collectively described as algae, which is a term of convenience as not all algae are closely related. algae comprise several distinct clades such as glaucophytes, which are microscopic freshwater algae that may have resembled in form to the early unicellular ancestor of plantae. unlike glaucophytes, the other algal clades such as red and green algae are multicellular. green algae comprise three major clades : chlorophytes, coleochaetophytes, and stoneworts. fungi are eukaryotes that digest foods outside their bodies, secreting digestive enzymes that break down large food molecules before absorbing them through their cell membranes. many fungi are also saprobes, feeding on dead organic matter, making them important decomposers in ecological systems. animals are multicellular eukaryotes. with few exceptions, animals likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, invertebrates, or protozoans, the protist grouping is not a formal taxonomic group but is used for convenience. most protists are unicellular ; these are called microbial eukaryotes. plants are mainly multicellular organisms, predominantly photosynthetic eukaryotes of the kingdom plantae, which would exclude fungi and some algae. plant cells were derived by endosymbiosis of a cyanobacterium into an early eukaryote about one billion years ago, which gave rise to chloroplasts. the first several clades that emerged following primary endosymbiosis were aquatic and most of the aquatic photosynthetic eukaryotic organisms are collectively described as algae, which is a term of convenience as not all algae are closely related. algae comprise several distinct clades such as glaucophytes, which are microscopic freshwater algae that may have resembled in form to the early unicellular ancestor of plantae. unlike glaucophytes, the other algal clades such as red and green algae are multicellular. green algae comprise three major clades : chlorophytes, coleochaetophytes, and stoneworts. fungi are eukaryotes that digest foods outside their bodies, secreting digestive enzymes that break down large food molecules before absorbing them through their cell membranes. many fungi are also saprobes, feeding on dead organic matter, making them important decomposers in ecological systems. animals are multicellular eukaryotes. with few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the two groups are not closely related. the cladistic method takes a systematic approach to characters, distinguishing between those that carry no information about shared evolutionary history – such as those evolved separately in different groups ( homoplasies ) or those left over from ancestors ( plesiomorphies ) – and derived characters, which by which botanists group organisms into categories such as genera or species. biological classification is a form of scientific taxonomy. modern taxonomy is rooted in the work of carl linnaeus, who grouped species according to shared physical characteristics. these groupings have since been revised to align better with the darwinian principle of common descent – grouping organisms by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the Question: Evolving from a single common ancestor, what group of organisms was perhaps the dominant life form on earth 250 million years ago? A) atoms B) acids C) fungi D) proteins	C) fungi
Context: a discontinuity of a turbulent ideal fluid is considered. it is supposed to be split and dispersed, or spread in the stochastic environment forming a gas without hydrostatic pressure. two equal - mass fragments of a discontinuity are indistinguishable from each other. a gas, that possesses such properties, must behave itself as the madelung medium. ##g mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, heat removes water. this step needs careful control, as rapid heating causes cracks and surface defects. the dried part is smaller than the green part, and is brittle, necessitating careful handling, since a small impact will cause crumbling and breaking. sintering is where the dried parts pass through a controlled heating process, and the oxides are chemically changed to cause bonding and densification. the fired part will be smaller than the dried part. = = forming methods = = ceramic forming techniques include throwing, slipcasting, tape casting, freeze - casting, injection molding, dry pressing, isostatic pressing, hot isostatic pressing ( hip ), 3d printing and others. methods for forming ceramic powders into complex shapes are desirable in many areas of technology. such methods are required for producing advanced, high - temperature structural parts such as heat engine components and turbines. materials other than ceramics which are used in these processes may include : wood, metal, water, plaster and epoxy — most of which will be eliminated upon firing. a ceramic - filled epoxy, such as martyte, is sometimes used to protect structural steel under conditions of rocket exhaust impingement. these forming techniques are well known for providing tools and other components with dimensional stability, surface quality, high ( near theoretical ) density and microstructural uniformity. the increasing use and diversity of specialty forms of ceramics adds to the diversity of process technologies to be used. thus, reinforcing fibers and filaments are mainly made by polymer, sol - gel, or cvd processes, but melt two possible interpretations of frw cosmologies ( perfect fluid or dissipative fluid ) are considered as consecutive phases of the system. necessary conditions are found, for the transition from perfect fluid to dissipative regime to occur, bringing out the conspicuous role played by a particular state of the system ( the ' ' critical point ' ' ). drag ( up to 15 % less during use ), and inertia ( for faster, stronger control response to change vehicle orientation to reduce detection ). two promising approaches are flexible wings, and fluidics. in flexible wings, much or all of a wing surface can change shape in flight to deflect air flow. adaptive compliant wings are a military and commercial effort. the x - 53 active aeroelastic wing was a us air force, boeing, and nasa effort. in fluidics, fluid injection into airflows is being researched for use in aircraft to control direction, in two ways : circulation control and thrust vectoring. in both, larger more complex mechanical parts are replaced by smaller, simpler, lower mass fluidic systems, in which larger forces in fluids are diverted by smaller jets or flows of fluid intermittently, to change the direction of vehicles. mechanical control surfaces that must move cause an important part of aircraft radar cross - section. omitting mechanical control surfaces can reduce radar returns. as of 2023, at least two countries are known to be researching fluidic control. in britain, bae systems has tested two fluidically controlled unmanned aircraft, one starting in 2010 named demon, and another starting in 2017 named magma, with the university of manchester. in the united states, the defense advanced research projects agency ( darpa ) program named control of revolutionary aircraft with novel effectors ( crane ) seeks "... to design, build, and flight test a novel x - plane that incorporates active flow control ( afc ) as a primary design consideration.... in 2023, the aircraft received its official designation as x - 65. " in january 2024, construction began, at boeing subsidiary aurora flight sciences. according to darpa, the aurora x - 65 could be completed and unveiled as soon as early 2025, with the first flight occurring in summer 2025. in circulation control, near the trailing edges of wings, aircraft flight control systems are replaced by slots which emit fluid flows. = = list of stealth aircraft = = f - 117 nighthawk b - 2 spirit f - 22 raptor f - 35 lightning ii j - 20 su - 57 b - 21 raider fc - 31 su - 75 checkmate = = list of stealth helicopters = = boeing – sikorsky rah - 66 comanche hughes 500p = = list of reduced - signature ships = = navy ships worldwide have incorporated signature - reduction features, mostly for the purpose of reducing anti - ship missile detection range and enhancing countermeasure effectiveness in this article i explain in detail a method for making small amounts of liquid oxygen in the classroom if there is no access to a cylinder of compressed oxygen gas. i also discuss two methods for identifying the fact that it is liquid oxygen as opposed to liquid nitrogen. also known as the gradient or slope. when two rivers of different sizes have the same fall, the larger river has the quicker flow, as its retardation by friction against its bed and banks is less in proportion to its volume than is the case with the smaller river. the fall available in a section of a river approximately corresponds to the slope of the country it traverses ; as rivers rise close to the highest part of their basins, generally in hilly regions, their fall is rapid near their source and gradually diminishes, with occasional irregularities, until, in traversing plains along the latter part of their course, their fall usually becomes quite gentle. accordingly, in large basins, rivers in most cases begin as torrents with a variable flow, and end as gently flowing rivers with a comparatively regular discharge. the irregular flow of rivers throughout their course forms one of the main difficulties in devising works for mitigating inundations or for increasing the navigable capabilities of rivers. in tropical countries subject to periodical rains, the rivers are in flood during the rainy season and have hardly any flow during the rest of the year, while in temperate regions, where the rainfall is more evenly distributed throughout the year, evaporation causes the available rainfall to be much less in hot summer weather than in the winter months, so that the rivers fall to their low stage in the summer and are liable to be in flood in the winter. in fact, with a temperate climate, the year may be divided into a warm and a cold season, extending from may to october and from november to april in the northern hemisphere respectively ; the rivers are low and moderate floods are of rare occurrence during the warm period, and the rivers are high and subject to occasional heavy floods after a considerable rainfall during the cold period in most years. the only exceptions are rivers which have their sources amongst mountains clad with perpetual snow and are fed by glaciers ; their floods occur in the summer from the melting of snow and ice, as exemplified by the rhone above the lake of geneva, and the arve which joins it below. but even these rivers are liable to have their flow modified by the influx of tributaries subject to different conditions, so that the rhone below lyon has a more uniform discharge than most rivers, as the summer floods of the arve are counteracted to a great extent by the low stage of the saone flowing into the rhone at lyon, which has its floods in the winter when the arve, on the contrary, is low. another serious obstacle encountered in river engineering consists in muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up the muck tube. the pressurized air flow must be constant to ensure regular air changes for the workers and prevent excessive inflow of mud or water at the base of the caisson. when the caisson hits bedrock, the sandhogs exit through the airlock and fill the box with concrete, forming a solid foundation pier. a pneumatic ( compressed - air ) caisson has the advantage of providing dry working conditions, which is better for placing concrete. it is also well suited for foundations for which other methods might cause settlement of adjacent structures. construction workers who leave the pressurized environment of the caisson must decompress at a rate that allows symptom - free release of inert gases dissolved in the body tissues if they are to avoid decompression sickness, a condition first identified in caisson workers, and originally named " caisson disease " in recognition of the occupational hazard. construction of the brooklyn bridge, which was built with the help of pressurised caissons, resulted in numerous workers being either killed or permanently injured by caisson disease during its construction. barotrauma of the ears, sinus cavities and lungs and dysbaric osteonecrosis are other risks. = = other uses = = caissons have also been used in the installation of hydraulic elevators where a single - stage ram is installed below the ground level. caissons, codenamed phoenix, were an integral part of the mulberry harbours used during the world war ii allied invasion of normandy. = = other meanings = = boat lift caissons : the word caisson is also used as a synonym for the moving trough part of caisson locks, canal lifts and inclines in which boats and ships rest while being lifted from one canal elevation to another ; the water is retained on the inside of the caisson, or excluded from the caisson, according to the respective operating principle. structural caissons : caisson is also sometimes used as a colloquial term for a reinforced concrete structure formed by pouring into a hollow cylindrical form, typically by placing a caisson form below grade in an open excavation and pouring once backfill is complete, or by ##s ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up the muck tube. the pressurized air flow must be constant to ensure regular air changes for the workers and prevent excessive inflow of mud or water at the base of the caisson. when the caisson hits bedrock, the sandhogs exit through the airlock and fill the box with concrete, forming a solid foundation pier. a pneumatic ( compressed - air ) caisson has the advantage of providing dry working conditions, which is better for placing concrete. it is also well suited for foundations for which other methods might cause settlement of adjacent structures. construction workers who leave the pressurized environment of the caisson must decompress at a rate that allows symptom - free release of inert gases dissolved in the body tissues if they are to avoid decompression sickness, a condition first identified in caisson workers, and originally named " caisson disease " in recognition of the occupational hazard. construction of the brooklyn bridge, which was built with the help of pressurised caissons, resulted in numerous workers being either killed or permanently injured by caisson disease during its construction. barotrauma of the ears, sinus cavities and lungs and dysbaric osteonecrosis are other risks. = = other uses = = caissons have also been used in the installation of hydraulic elevators where a single - stage ram is installed below the ground level. caissons, codenamed phoenix, were an integral part of the mulberry harbours used during the world war ii allied invasion of normandy. = = other meanings = = boat lift caissons : the word caisson is also used as a synonym for the moving trough part of caisson locks, canal lifts and inclines in which boats and ships rest while being lifted from one canal elevation to another ; the water is retained on the inside of the caisson, or excluded from the caisson or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for discharge than most rivers, as the summer floods of the arve are counteracted to a great extent by the low stage of the saone flowing into the rhone at lyon, which has its floods in the winter when the arve, on the contrary, is low. another serious obstacle encountered in river engineering consists in the large quantity of detritus they bring down in flood - time, derived mainly from the disintegration of the surface layers of the hills and slopes in the upper parts of the valleys by glaciers, frost and rain. the power of a current to transport materials varies with its velocity, so that torrents with a rapid fall near the sources of rivers can carry down rocks, boulders and large stones, which are by degrees ground by attrition in their onward course into slate, gravel, sand and silt, simultaneously with the gradual reduction in fall, and, consequently, in the transporting force of the current. accordingly, under ordinary conditions, most of the materials brought down from the high lands by torrential water courses are carried forward by the main river to the sea, or partially strewn over flat alluvial plains during floods ; the size of the materials forming the bed of the river or borne along by the stream is gradually reduced on proceeding seawards, so that in the po river in italy, for instance, pebbles and gravel are found for about 140 miles below turin, sand along the next 100 miles, and silt and mud in the last 110 miles ( 176 km ). = = channelization = = the removal of obstructions, natural or artificial ( e. g., trunks of trees, boulders and accumulations of gravel ) from a river bed furnishes a simple and efficient means of increasing the discharging capacity of its channel. such removals will consequently lower the height of floods upstream. every impediment to the flow, in proportion to its extent, raises the level of the river above it so as to produce the additional artificial fall necessary to convey the flow through the restricted channel, thereby reducing the total available fall. reducing the length of the channel by substituting straight cuts for a winding course is the only way in which the effective fall can be increased. this involves some loss of capacity in the channel as a whole, and in the case of a large river with a considerable flow it is difficult to maintain a straight cut owing to the tendency of the current to erode the banks and form again a sinuous channel. even if the cut is preserved by protecting the banks, Question: What two forms can fluids take? A) vapor or gas B) liquid or gas C) mixture or gas D) water or gas	B) liquid or gas
Context: ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, not completely stable as each water molecule continuously dissociates into hydrogen and hydroxyl ions before reforming into a water molecule again. in pure water, the number of hydrogen ions balances ( or equals ) the number of hydroxyl ions, resulting in a ph that is neutral. = = = organic compounds = = = organic compounds are molecules that contain carbon bonded to another element such as hydrogen. with the exception of water, nearly all the molecules that make up each organism contain carbon. carbon can form covalent bonds with up to four other atoms, enabling it to form diverse, large, and complex molecules. for example, a single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such as octane or ring - like structures such as glucose. the simplest form of an organic molecule is the hydrocarbon, which is a large family of organic compounds that are composed of hydrogen atoms bonded to a chain of carbon atoms. a hydrocarbon backbone can be substituted by other elements such as oxygen ( o ), hydrogen ( h ), phosphorus ( p ), and sulfur ( s ), which can change the chemical behavior of that compound. groups of atoms that contain these elements ( o -, h -, p -, and s - ) and are bonded to a central carbon atom or skeleton are called functional groups. there are six prominent functional groups that can be found in organisms : amino group, carboxyl group, carbonyl group, hydroxyl group, phosphate group, and sulfhydryl group. in 1953, the miller – urey experiment showed that organic compounds could be synthesized abiotically within a closed system mimicking the conditions of early earth, thus suggesting that complex organic molecules could have arisen spontaneously in early earth ( see abiogenesis ). = = = macromolecules = = = macromolecules are large molecules made up of smaller subunits or monomers. monomers include sugars, amino acids, and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws, which have become fundamental concepts in chemistry. some of them are : = = history = = the history of chemistry spans a period from the ancient past to the present. since several millennia bc, civilizations were using technologies that would eventually form the basis of the various branches of chemistry. examples include extracting metals from ores ##ulating the liquid below from the cold air above. water has the capacity to absorb energy, giving it a higher specific heat capacity than other solvents such as ethanol. thus, a large amount of energy is needed to break the hydrogen bonds between water molecules to convert liquid water into water vapor. as a molecule, water is not completely stable as each water molecule continuously dissociates into hydrogen and hydroxyl ions before reforming into a water molecule again. in pure water, the number of hydrogen ions balances ( or equals ) the number of hydroxyl ions, resulting in a ph that is neutral. = = = organic compounds = = = organic compounds are molecules that contain carbon bonded to another element such as hydrogen. with the exception of water, nearly all the molecules that make up each organism contain carbon. carbon can form covalent bonds with up to four other atoms, enabling it to form diverse, large, and complex molecules. for example, a single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such as octane or ring - like structures such as glucose. the simplest form of an organic molecule is the hydrocarbon, which is a large family of organic compounds that are composed of hydrogen atoms bonded to a chain of carbon atoms. a hydrocarbon backbone can be substituted by other elements such as oxygen ( o ), hydrogen ( h ), phosphorus ( p ), and sulfur ( s ), which can change the chemical behavior of that compound. groups of atoms that contain these elements ( o -, h -, p -, and s - ) and are bonded to a central carbon atom or skeleton are called functional groups. there are six prominent functional groups that can be found in organisms : amino group, carboxyl group, carbonyl group, hydroxyl group, phosphate group, and sulfhydryl group. in 1953, the miller – urey experiment showed that organic compounds could be synthesized abiotically within a closed system mimicking the conditions of early earth, thus suggesting that complex organic molecules could have arisen spontaneously in early earth ( see abiogenesis ). = = = macromolecules = = = macromolecules are large molecules made up of smaller subunits or monomers. monomers include sugars, amino acids, classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron , the oxygen atom has a slight negative charge and the two hydrogen atoms have a slight positive charge. this polar property of water allows it to attract other water molecules via hydrogen bonds, which makes water cohesive. surface tension results from the cohesive force due to the attraction between molecules at the surface of the liquid. water is also adhesive as it is able to adhere to the surface of any polar or charged non - water molecules. water is denser as a liquid than it is as a solid ( or ice ). this unique property of water allows ice to float above liquid water such as ponds, lakes, and oceans, thereby insulating the liquid below from the cold air above. water has the capacity to absorb energy, giving it a higher specific heat capacity than other solvents such as ethanol. thus, a large amount of energy is needed to break the hydrogen bonds between water molecules to convert liquid water into water vapor. as a molecule, water is not completely stable as each water molecule continuously dissociates into hydrogen and hydroxyl ions before reforming into a water molecule again. in pure water, the number of hydrogen ions balances ( or equals ) the number of hydroxyl ions, resulting in a ph that is neutral. = = = organic compounds = = = organic compounds are molecules that contain carbon bonded to another element such as hydrogen. with the exception of water, nearly all the molecules that make up each organism contain carbon. carbon can form covalent bonds with up to four other atoms, enabling it to form diverse, large, and complex molecules. for example, a single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such as octane or ring - like structures such as glucose. the simplest form of an organic molecule is the hydrocarbon, which is a large family of organic compounds that are composed of hydrogen atoms bonded to a chain of carbon atoms. a hydrocarbon backbone can be substituted by other elements such as oxygen ( o ), hydrogen ( h ), phosphorus ( p ), and sulfur ( s ), which can change the chemical behavior of that compound. groups of atoms that contain these elements ( o -, h -, p -, and s - ) and are bonded to a central carbon atom or skeleton are called functional groups. there are six superdielectric behavior was observed in pastes made of high surface area alumina filled to the level of incipient wetness with water containing dissolved sodium chloride ( table salt ). in some cases the dielectric constants were greater than 10 ^ 10. Question: What are ionic compounds that produce hydroxide ions when dissolved in water? A) isotopes B) bases C) acids D) enzymes	B) bases
Context: ##wi, turkana, dating from 3. 3 million years ago. stone tools diversified through the pleistocene period, which ended ~ 12, 000 years ago. the earliest evidence of warfare between two groups is recorded at the site of nataruk in turkana, kenya, where human skeletons with major traumatic injuries to the head, neck, ribs, knees and hands, including an embedded obsidian bladelet on a skull, are evidence of inter - group conflict between groups of nomadic hunter - gatherers 10, 000 years ago. humans entered the bronze age as they learned to smelt copper into an alloy with tin to make weapons. in asia where copper - tin ores are rare, this development was delayed until trading in bronze began in the third millennium bce. in the middle east and southern european regions, the bronze age follows the neolithic period, but in other parts of the world, the copper age is a transition from neolithic to the bronze age. although the iron age generally follows the bronze age, in some areas the iron age intrudes directly on the neolithic from outside the region, with the exception of sub - saharan africa where it was developed independently. the first large - scale use of iron weapons began in asia minor around the 14th century bce and in central europe around the 11th century bce followed by the middle east ( about 1000 bce ) and india and china. the assyrians are credited with the introduction of horse cavalry in warfare and the extensive use of iron weapons by 1100 bce. assyrians were also the first to use iron - tipped arrows. = = = post - classical technology = = = the wujing zongyao ( essentials of the military arts ), written by zeng gongliang, ding du, and others at the order of emperor renzong around 1043 during the song dynasty illustrate the eras focus on advancing intellectual issues and military technology due to the significance of warfare between the song and the liao, jin, and yuan to their north. the book covers topics of military strategy, training, and the production and employment of advanced weaponry. advances in military technology aided the song dynasty in its defense against hostile neighbors to the north. the flamethrower found its origins in byzantine - era greece, employing greek fire ( a chemically complex, highly flammable petrol fluid ) in a device with a siphon hose by the 7th century. : 77 the earliest reference to greek fire in china was made in 917, written by wu renchen in his spring and autumn annals of the ten kingdoms. : 80 in 91 the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy ". = = extraction = = extractive metallurgy is the practice of removing valuable metals from an ore and refining the extracted raw metals into a purer form. in order to convert a metal oxide or sulphide to a purer metal, the ore must be reduced physically, chemically, or electrolytically. extractive metallurgists are interested in three primary streams : feed, concentrate ( metal oxide / sulphide ) and tailings ( waste ). after mining, large pieces of the ore feed are broken through crushing or grinding in order to obtain particles small enough, where each particle is either mostly valuable or mostly waste. concentrating the particles of value in a form supporting separation enables the desired metal to be removed from waste products. mining may not be necessary, if the ore body and physical environment are conducive to leaching. leaching dissolves minerals in an ore body and results in an enriched solution. the solution ancient endosymbiotic relationship between an ancestral eukaryotic cell and a cyanobacterial resident. the algae are a polyphyletic group and are placed in various divisions, some more closely related to plants than others. there are many differences between them in features such as cell wall composition, biochemistry, pigmentation, chloroplast structure and nutrient reserves. the algal division charophyta, sister to the green algal division chlorophyta, is considered to contain the ancestor of true plants. the charophyte class charophyceae and the land plant sub - kingdom embryophyta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an o an oscillation with a period of around 500 kb in guanine and cytosine content ( gc % ) is observed in the dna sequence of human chromosome 21. this oscillation is localized in the rightmost one - eighth region of the chromosome, from 43. 5 mb to 46. 5 mb. five cycles of oscillation are observed in this region with six gc - rich peaks and five gc - poor valleys. the gc - poor valleys comprise regions with low density of cpg islands and, alternating between the two dna strands, low gene density regions. consequently, the long - range oscillation of gc % result in spacing patterns of both cpg island density, and to a lesser extent, gene densities. ##nita and hamangia, which are often grouped together under the name of ' old europe '. with the carpatho - balkan region described as the ' earliest metallurgical province in eurasia ', its scale and technical quality of metal production in the 6th – 5th millennia bc totally overshadowed that of any other contemporary production centre. the earliest documented use of lead ( possibly native or smelted ) in the near east dates from the 6th millennium bc, is from the late neolithic settlements of yarim tepe and arpachiyah in iraq. the artifacts suggest that lead smelting may have predated copper smelting. metallurgy of lead has also been found in the balkans during the same period. copper smelting is documented at sites in anatolia and at the site of tal - i iblis in southeastern iran from c. 5000 bc. copper smelting is first documented in the delta region of northern egypt in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and ##elting. metallurgy of lead has also been found in the balkans during the same period. copper smelting is documented at sites in anatolia and at the site of tal - i iblis in southeastern iran from c. 5000 bc. copper smelting is first documented in the delta region of northern egypt in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy pigmentation, chloroplast structure and nutrient reserves. the algal division charophyta, sister to the green algal division chlorophyta, is considered to contain the ancestor of true plants. the charophyte class charophyceae and the land plant sub - kingdom embryophyta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form ##nik, in present - day serbia. the site of plocnik has produced a smelted copper axe dating from 5, 500 bc, belonging to the vinca culture. the balkans and adjacent carpathian region were the location of major chalcolithic cultures including vinca, varna, karanovo, gumelnita and hamangia, which are often grouped together under the name of ' old europe '. with the carpatho - balkan region described as the ' earliest metallurgical province in eurasia ', its scale and technical quality of metal production in the 6th – 5th millennia bc totally overshadowed that of any other contemporary production centre. the earliest documented use of lead ( possibly native or smelted ) in the near east dates from the 6th millennium bc, is from the late neolithic settlements of yarim tepe and arpachiyah in iraq. the artifacts suggest that lead smelting may have predated copper smelting. metallurgy of lead has also been found in the balkans during the same period. copper smelting is documented at sites in anatolia and at the site of tal - i iblis in southeastern iran from c. 5000 bc. copper smelting is first documented in the delta region of northern egypt in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin . species boundaries in plants may be weaker than in animals, and cross species hybrids are often possible. a familiar example is peppermint, mentha × piperita, a sterile hybrid between mentha aquatica and spearmint, mentha spicata. the many cultivated varieties of wheat are the result of multiple inter - and intra - specific crosses between wild species and their hybrids. angiosperms with monoecious flowers often have self - incompatibility mechanisms that operate between the pollen and stigma so that the pollen either fails to reach the stigma or fails to germinate and produce male gametes. this is one of several methods used by plants to promote outcrossing. in many land plants the male and female gametes are produced by separate individuals. these species are said to be dioecious when referring to vascular plant sporophytes and dioicous when referring to bryophyte gametophytes. charles darwin in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy ". = = extraction = = extractive metallurgy is the practice of removing valuable metals from an ore and refining the extracted raw metals into a purer form. in order to convert a metal oxide or sulphide to a purer metal, the ore must be reduced physically, chemically, or electroly Question: When do end portions of two nonsister chromatids trade places? A) during respiration B) never C) at every crossover D) at night	C) at every crossover
Context: ##trophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist frits went. the first known auxin, indole - 3 - acetic acid ( iaa ), which promotes cell growth, was only isolated from plants about 50 years later. this compound mediates the tropic responses of shoots and roots towards light and gravity. the finding in 1939 that plant callus the structural components of cells. as a by - product of photosynthesis, plants release oxygen into the atmosphere, a gas that is required by nearly all living things to carry out cellular respiration. in addition, they are influential in the global carbon and water cycles and plant roots bind and stabilise soils, preventing soil erosion. plants are crucial to the future of human society as they provide food, oxygen, biochemicals, and products for people, as well as creating and preserving soil. historically, all living things were classified as either animals or plants and botany covered the study of all organisms not considered animals. botanists examine both the internal functions and processes within plant organelles, cells, tissues, whole plants, plant populations and plant communities. at each of these levels, a botanist may be concerned with the classification ( taxonomy ), phylogeny and evolution, structure ( anatomy and morphology ), or function ( physiology ) of plant life. the strictest definition of " plant " includes only the " land plants " or embryophytes, which include seed plants ( gymnosperms, including the pines, and flowering plants ) and the free - sporing cryptogams including ferns, clubmosses, liverworts, hornworts and mosses. embryophytes are multicellular eukaryotes descended from an ancestor that obtained its energy from sunlight by photosynthesis. they have life cycles with alternating haploid and diploid phases. the sexual haploid phase of embryophytes, known as the gametophyte, nurtures the developing diploid embryo sporophyte within its tissues for at least part of its life, even in the seed plants, where the gametophyte itself is nurtured by its parent sporophyte. other groups of organisms that were previously studied by botanists include bacteria ( now studied in bacteriology ), fungi ( mycology ) – including lichen - forming fungi ( lichenology ), non - chlorophyte algae ( phycology ), and viruses ( virology ). however, attention is still given to these groups by botanists, and fungi ( including lichens ) and photosynthetic protists are usually covered in introductory botany courses. palaeobotanists study ancient plants in the fossil record to provide information about the evolutionary history of plants. cyanobacteria, the first oxygen - releasing photosynthetic organisms on earth, are thought to have given rise to the the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist horticultural botany, phytopathology, and phytopharmacology. = = scope and importance = = the study of plants is vital because they underpin almost all animal life on earth by generating a large proportion of the oxygen and food that provide humans and other organisms with aerobic respiration with the chemical energy they need to exist. plants, algae and cyanobacteria are the major groups of organisms that carry out photosynthesis, a process that uses the energy of sunlight to convert water and carbon dioxide into sugars that can be used both as a source of chemical energy and of organic molecules that are used in the structural components of cells. as a by - product of photosynthesis, plants release oxygen into the atmosphere, a gas that is required by nearly all living things to carry out cellular respiration. in addition, they are influential in the global carbon and water cycles and plant roots bind and stabilise soils, preventing soil erosion. plants are crucial to the future of human society as they provide food, oxygen, biochemicals, and products for people, as well as creating and preserving soil. historically, all living things were classified as either animals or plants and botany covered the study of all organisms not considered animals. botanists examine both the internal functions and processes within plant organelles, cells, tissues, whole plants, plant populations and plant communities. at each of these levels, a botanist may be concerned with the classification ( taxonomy ), phylogeny and evolution, structure ( anatomy and morphology ), or function ( physiology ) of plant life. the strictest definition of " plant " includes only the " land plants " or embryophytes, which include seed plants ( gymnosperms, including the pines, and flowering plants ) and the free - sporing cryptogams including ferns, clubmosses, liverworts, hornworts and mosses. embryophytes are multicellular eukaryotes descended from an ancestor that obtained its energy from sunlight by photosynthesis. they have life cycles with alternating haploid and diploid phases. the sexual haploid phase of embryophytes, known as the gametophyte, nurtures the developing diploid embryo sporophyte within its tissues for at least part of its life, even in the seed plants, where the gametophyte itself is nurtured by its parent sporophyte. other groups of organisms that were previously studied by botanists include bacteria ( now studied in bacteriology ) decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream and taken up by the brain. by observing which areas of the brain take up the radioactive isotope, we can see which areas of the brain are more active than other areas. pet has similar spatial resolution to fmri, but it has extremely poor temporal resolution. electroencephalography. eeg measures the electrical fields generated by large populations of neurons in the cortex by placing a series of electrodes on the scalp of the subject. this technique has an extremely high temporal resolution, but a relatively poor spatial resolution. functional magnetic resonance imaging. fmri measures the relative amount of oxygenated blood flowing to different parts of the brain. more oxygenated blood in a particular region is assumed to correlate with an increase in neural activity in that part of the brain. this allows us to localize particular functions within different brain regions. fmri has moderate spatial and temporal resolution. optical imaging. this technique uses infrared transmitters and receivers to measure the amount of light reflectance by blood near different areas of the brain. since oxygenated and deoxygenated blood reflects light by different amounts, we can study which areas are more active ( i. e., those that have more oxygenated blood ). optical imaging has moderate temporal resolution, but poor spatial resolution. it also has the advantage that it is extremely safe and can be used to study infants ' brains. magnetoencephalography. meg measures magnetic fields resulting from cortical activity. it is similar to eeg, except that it has improved spatial resolution since the magnetic fields it measures are not as blurred or attenuated by the scalp, meninges and so forth as the electrical activity measured in eeg is. meg uses squid sensors to detect tiny magnetic fields. = = = computational modeling = = = computational models require a mathematically and logically formal representation of a problem. computer models are used in the simulation and experimental verification of different oxygen ion migration in li2mno3 was systematically studied by first - principles calculations. hole polaron is found effective to lower the migration barrier of oxygen ion. digest foods outside their bodies, secreting digestive enzymes that break down large food molecules before absorbing them through their cell membranes. many fungi are also saprobes, feeding on dead organic matter, making them important decomposers in ecological systems. animals are multicellular eukaryotes. with few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea. more than 6, 000 virus species have been described in detail. viruses are found in almost every ecosystem on earth and are the most numerous type of biological entity. the origins of viruses in the evolutionary history of life are unclear : some may have evolved from plasmids — pieces of dna that can move between cells — while others may have evolved from bacteria. in evolution, viruses are an important means of horizontal gene transfer, which increases genetic diversity in a way analogous to sexual reproduction. because viruses possess some but not all characteristics of life, they have been described as " organisms at the edge of life ", and as self - replicators. = = ecology = = ecology is the study of the distribution and abundance of life, the interaction between organisms and their environment. = = = ecosystems = = = the community of living ( biotic ) organisms in conjunction with the nonliving ( abiotic ) components ( e. g., water, light, radiation, temperature, humidity, atmosphere, acidity, and soil ) of their environment is called an ecosystem. these biotic and abiotic components are linked together through nutrient cycles and energy flows. energy from the sun enters the system through photosynthesis and is incorporated into plant tissue. by feeding on plants and on one another, animals move matter and energy through the system. they also influence the quantity of plant and microbial biomass present. by breaking down dead organic matter, decomposers release carbon back to the atmosphere and facilitate nutrient cycling by converting nutrients stored in dead biomass back to a form , characterizing organs as predominantly yin or yang, and understood the relationship between the pulse, the heart, and the flow of blood in the body centuries before it became accepted in the west. little evidence survives of how ancient indian cultures around the indus river understood nature, but some of their perspectives may be reflected in the vedas, a set of sacred hindu texts. they reveal a conception of the universe as ever - expanding and constantly being recycled and reformed. surgeons in the ayurvedic tradition saw health and illness as a combination of three humors : wind, bile and phlegm. a healthy life resulted from a balance among these humors. in ayurvedic thought, the body consisted of five elements : earth, water, fire, wind, and space. ayurvedic surgeons performed complex surgeries and developed a detailed understanding of human anatomy. pre - socratic philosophers in ancient greek culture brought natural philosophy a step closer to direct inquiry about cause and effect in nature between 600 and 400 bc. however, an element of magic and mythology remained. natural phenomena such as earthquakes and eclipses were explained increasingly in the context of nature itself instead of being attributed to angry gods. thales of miletus, an early philosopher who lived from 625 to 546 bc, explained earthquakes by theorizing that the world floated on water and that water was the fundamental element in nature. in the 5th century bc, leucippus was an early exponent of atomism, the idea that the world is made up of fundamental indivisible particles. pythagoras applied greek innovations in mathematics to astronomy and suggested that the earth was spherical. = = = aristotelian natural philosophy ( 400 bc – 1100 ad ) = = = later socratic and platonic thought focused on ethics, morals, and art and did not attempt an investigation of the physical world ; plato criticized pre - socratic thinkers as materialists and anti - religionists. aristotle, however, a student of plato who lived from 384 to 322 bc, paid closer attention to the natural world in his philosophy. in his history of animals, he described the inner workings of 110 species, including the stingray, catfish and bee. he investigated chick embryos by breaking open eggs and observing them at various stages of development. aristotle ' s works were influential through the 16th century, and he is considered to be the father of biology for his pioneering work in that science. he also presented philosophies about physics, nature, and astronomy using the decomposition theorem is deduced from local purity. ##vary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an ex Question: Through which part of the body do most animals take in oxygen? A) nose B) mouth C) rectum D) ears	B) mouth
Context: which constitutes anywhere from 30 % [ m / m ] to 90 % [ m / m ] of its composition by volume, yielding an array of materials with interesting thermomechanical properties. in the processing of glass - ceramics, molten glass is cooled down gradually before reheating and annealing. in this heat treatment the glass partly crystallizes. in many cases, so - called ' nucleation agents ' are added in order to regulate and control the crystallization process. because there is usually no pressing and sintering, glass - ceramics do not contain the volume fraction of porosity typically present in sintered ceramics. the term mainly refers to a mix of lithium and aluminosilicates which yields an array of materials with interesting thermomechanical properties. the most commercially important of these have the distinction of being impervious to thermal shock. thus, glass - ceramics have become extremely useful for countertop cooking. the negative thermal expansion coefficient ( tec ) of the crystalline ceramic phase can be balanced with the positive tec of the glassy phase. at a certain point ( ~ 70 % crystalline ) the glass - ceramic has a net tec near zero. this type of glass - ceramic exhibits excellent mechanical properties and can sustain repeated and quick temperature changes up to 1000 °c. = = processing steps = = the traditional ceramic process generally follows this sequence : milling → batching → mixing → forming → drying → firing → assembly. milling is the process by which materials are reduced from a large size to a smaller size. milling may involve breaking up cemented material ( in which case individual particles retain their shape ) or pulverization ( which involves grinding the particles themselves to a smaller size ). milling is generally done by mechanical means, including attrition ( which is particle - to - particle collision that results in agglomerate break up or particle shearing ), compression ( which applies a forces that results in fracturing ), and impact ( which employs a milling medium or the particles themselves to cause fracturing ). attrition milling equipment includes the wet scrubber ( also called the planetary mill or wet attrition mill ), which has paddles in water creating vortexes in which the material collides and break up. compression mills include the jaw crusher, roller crusher and cone crusher. impact mills include the ball mill, which has media that tumble and fracture the material, or the resonantacoustic mixer. shaft impactors cause particle - to particle attrition and compression building block. ceramics – not to be confused with raw, unfired clay – are usually seen in crystalline form. the vast majority of commercial glasses contain a metal oxide fused with silica. at the high temperatures used to prepare glass, the material is a viscous liquid which solidifies into a disordered state upon cooling. windowpanes and eyeglasses are important examples. fibers of glass are also used for long - range telecommunication and optical transmission. scratch resistant corning gorilla glass is a well - known example of the application of materials science to drastically improve the properties of common components. engineering ceramics are known for their stiffness and stability under high temperatures, compression and electrical stress. alumina, silicon carbide, and tungsten carbide are made from a fine powder of their constituents in a process of sintering with a binder. hot pressing provides higher density material. chemical vapor deposition can place a film of a ceramic on another material. cermets are ceramic particles containing some metals. the wear resistance of tools is derived from cemented carbides with the metal phase of cobalt and nickel typically added to modify properties. ceramics can be significantly strengthened for engineering applications using the principle of crack deflection. this process involves the strategic addition of second - phase particles within a ceramic matrix, optimizing their shape, size, and distribution to direct and control crack propagation. this approach enhances fracture toughness, paving the way for the creation of advanced, high - performance ceramics in various industries. = = = composites = = = another application of materials science in industry is making composite materials. these are structured materials composed of two or more macroscopic phases. applications range from structural elements such as steel - reinforced concrete, to the thermal insulating tiles, which play a key and integral role in nasa ' s space shuttle thermal protection system, which is used to protect the surface of the shuttle from the heat of re - entry into the earth ' s atmosphere. one example is reinforced carbon - carbon ( rcc ), the light gray material, which withstands re - entry temperatures up to 1, 510 °c ( 2, 750 °f ) and protects the space shuttle ' s wing leading edges and nose cap. rcc is a laminated composite material made from graphite rayon cloth and impregnated with a phenolic resin. after curing at high temperature in an autoclave, the laminate is pyrolized to convert the resin to carbon, impregnated with furfuryl alcohol in a high machining costs. there is a possibility for melt casting to be used for many of these approaches. potentially even more desirable is using melt - derived particles. in this method, quenching is done in a solid solution or in a fine eutectic structure, in which the particles are then processed by more typical ceramic powder processing methods into a useful body. there have also been preliminary attempts to use melt spraying as a means of forming composites by introducing the dispersed particulate, whisker, or fiber phase in conjunction with the melt spraying process. other methods besides melt infiltration to manufacture ceramic composites with long fiber reinforcement are chemical vapor infiltration and the infiltration of fiber preforms with organic precursor, which after pyrolysis yield an amorphous ceramic matrix, initially with a low density. with repeated cycles of infiltration and pyrolysis one of those types of ceramic matrix composites is produced. chemical vapor infiltration is used to manufacture carbon / carbon and silicon carbide reinforced with carbon or silicon carbide fibers. besides many process improvements, the first of two major needs for fiber composites is lower fiber costs. the second major need is fiber compositions or coatings, or composite processing, to reduce degradation that results from high - temperature composite exposure under oxidizing conditions. = = applications = = the products of technical ceramics include tiles used in the space shuttle program, gas burner nozzles, ballistic protection, nuclear fuel uranium oxide pellets, bio - medical implants, jet engine turbine blades, and missile nose cones. its products are often made from materials other than clay, chosen for their particular physical properties. these may be classified as follows : oxides : silica, alumina, zirconia non - oxides : carbides, borides, nitrides, silicides composites : particulate or whisker reinforced matrices, combinations of oxides and non - oxides ( e. g. polymers ). ceramics can be used in many technological industries. one application is the ceramic tiles on nasa ' s space shuttle, used to protect it and the future supersonic space planes from the searing heat of re - entry into the earth ' s atmosphere. they are also used widely in electronics and optics. in addition to the applications listed here, ceramics are also used as a coating in various engineering cases. an example would be a ceramic bearing coating over a titanium frame used for an aircraft. recently the field has come to include the studies of single the structural template or precursor which is created in the initial stages of chemical synthesis and physical forming. hence the importance of chemical powder and polymer processing as it pertains to the synthesis of industrial ceramics, glasses and glass - ceramics. there are numerous possible refinements of the sintering process. some of the most common involve pressing the green body to give the densification a head start and reduce the sintering time needed. sometimes organic binders such as polyvinyl alcohol are added to hold the green body together ; these burn out during the firing ( at 200 – 350 °c ). sometimes organic lubricants are added during pressing to increase densification. it is common to combine these, and add binders and lubricants to a powder, then press. ( the formulation of these organic chemical additives is an art in itself. this is particularly important in the manufacture of high performance ceramics such as those used by the billions for electronics, in capacitors, inductors, sensors, etc. ) a slurry can be used in place of a powder, and then cast into a desired shape, dried and then sintered. indeed, traditional pottery is done with this type of method, using a plastic mixture worked with the hands. if a mixture of different materials is used together in a ceramic, the sintering temperature is sometimes above the melting point of one minor component – a liquid phase sintering. this results in shorter sintering times compared to solid state sintering. such liquid phase sintering involves in faster diffusion processes and may result in abnormal grain growth. = = strength of ceramics = = a material ' s strength is dependent on its microstructure. the engineering processes to which a material is subjected can alter its microstructure. the variety of strengthening mechanisms that alter the strength of a material include the mechanism of grain boundary strengthening. thus, although yield strength is maximized with decreasing grain size, ultimately, very small grain sizes make the material brittle. considered in tandem with the fact that the yield strength is the parameter that predicts plastic deformation in the material, one can make informed decisions on how to increase the strength of a material depending on its microstructural properties and the desired end effect. the relation between yield stress and grain size is described mathematically by the hall - petch equation which is σ y = σ 0 + k y d { \ displaystyle \ sigma _ { y } = \ sigma _ { 0 } + { k _ { y } \ over { is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemical . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = , crystal structure, hazards associated with minerals, and the physical and chemical properties of minerals. petrology is the study of rocks, including the formation and composition of rocks. petrography is a branch of petrology that studies the typology and classification of rocks. = = earth ' s interior = = plate tectonics, mountain ranges, volcanoes, and earthquakes are geological phenomena that can be explained in terms of physical and chemical processes in the earth ' s crust. beneath the earth ' s crust lies the mantle which is heated by the radioactive decay of heavy elements. the mantle is not quite solid and consists of magma which is in a state of semi - perpetual convection. this convection process causes the lithospheric plates to move, albeit slowly. the resulting process is known as plate tectonics. areas of the crust where new crust is created are called divergent boundaries, those where it is brought back into the earth are convergent boundaries and those where plates slide past each other, but no new lithospheric material is created or destroyed, are referred to as transform ( or conservative ) boundaries. earthquakes result from the movement of the lithospheric plates, and they often occur near convergent boundaries where parts of the crust are forced into the earth as part of subduction. plate tectonics might be thought of as the process by which the earth is resurfaced. as the result of seafloor spreading, new crust and lithosphere is created by the flow of magma from the mantle to the near surface, through fissures, where it cools and solidifies. through subduction, oceanic crust and lithosphere vehemently returns to the convecting mantle. volcanoes result primarily from the melting of subducted crust material. crust material that is forced into the asthenosphere melts, and some portion of the melted material becomes light enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest was used before copper smelting was known. copper smelting is believed to have originated when the technology of pottery kilns allowed sufficiently high temperatures. the concentration of various elements such as arsenic increase with depth in copper ore deposits and smelting of these ores yields arsenical bronze, which can be sufficiently work hardened to be suitable for making tools. bronze is an alloy of copper with tin ; the latter being found in relatively few deposits globally caused a long time to elapse before true tin bronze became widespread. ( see : tin sources and trade in ancient times ) bronze was a major advancement over stone as a material for making tools, both because of its mechanical properties like strength and ductility and because it could be cast in molds to make intricately shaped objects. bronze significantly advanced shipbuilding technology with better tools and bronze nails. bronze nails replaced the old method of attaching boards of the hull with cord woven through drilled holes. better ships enabled long - distance trade and the advance of civilization. this technological trend apparently began in the fertile crescent and spread outward over time. these developments were not, and still are not, universal. the three - age system does not accurately describe the technology history of groups outside of eurasia, and does not apply at all in the case of some isolated populations, such as the spinifex people, the sentinelese, and various amazonian tribes, which still make use of stone age technology, and have not developed agricultural or metal technology. these villages preserve traditional customs in the face of global modernity, exhibiting a remarkable resistance to the rapid advancement of technology. = = = = iron age = = = = before iron smelting was developed the only iron was obtained from meteorites and is usually identified by having nickel content. meteoric iron was rare and valuable, but was sometimes used to make tools and other implements, such as fish hooks. the iron age involved the adoption of iron smelting technology. it generally replaced bronze and made it possible to produce tools which were stronger, lighter and cheaper to make than bronze equivalents. the raw materials to make iron, such as ore and limestone, are far more abundant than copper and especially tin ores. consequently, iron was produced in many areas. it was not possible to mass manufacture steel or pure iron because of the high temperatures required. furnaces could reach melting temperature but the crucibles and molds needed for melting and casting had not been developed. steel could be produced by forging bloomery iron to reduce the carbon content in a ##ctonics, mountain ranges, volcanoes, and earthquakes are geological phenomena that can be explained in terms of physical and chemical processes in the earth ' s crust. beneath the earth ' s crust lies the mantle which is heated by the radioactive decay of heavy elements. the mantle is not quite solid and consists of magma which is in a state of semi - perpetual convection. this convection process causes the lithospheric plates to move, albeit slowly. the resulting process is known as plate tectonics. areas of the crust where new crust is created are called divergent boundaries, those where it is brought back into the earth are convergent boundaries and those where plates slide past each other, but no new lithospheric material is created or destroyed, are referred to as transform ( or conservative ) boundaries. earthquakes result from the movement of the lithospheric plates, and they often occur near convergent boundaries where parts of the crust are forced into the earth as part of subduction. plate tectonics might be thought of as the process by which the earth is resurfaced. as the result of seafloor spreading, new crust and lithosphere is created by the flow of magma from the mantle to the near surface, through fissures, where it cools and solidifies. through subduction, oceanic crust and lithosphere vehemently returns to the convecting mantle. volcanoes result primarily from the melting of subducted crust material. crust material that is forced into the asthenosphere melts, and some portion of the melted material becomes light enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest layer. in all, the atmosphere is made up of about 78. 0 % nitrogen, 20. 9 % oxygen, and 0. 92 % argon, and small amounts of other gases including co2 and water vapor. water vapor and co2 cause the earth ' s atmosphere to catch and hold the sun ' s = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase which constitutes anywhere from 30 % [ m / m ] to 90 % [ m / m ] of its composition by volume, yielding an array of materials with interesting thermomechanical properties. in the processing of glass - ceramics, molten glass is cooled down gradually before reheating and annealing. in this heat treatment the glass partly crystallizes. in many cases, so - called ' nucleation agents ' are added in order to regulate and control the crystallization process. because there is usually no pressing and sintering, glass - ceramics do not contain the volume fraction of porosity typically present in sintered ceramics. the term mainly refers to a mix of lithium and aluminosilicates which yields an array of materials with interesting thermomechanical properties. the most commercially important of these have the distinction of being impervious to thermal shock. thus, glass - ceramics have become extremely useful for countertop cooking. the negative thermal expansion coefficient ( tec ) of the crystalline ceramic phase can be balanced with the positive tec of the glassy phase. at a certain point ( ~ 70 % crystalline ) the glass - ceramic has a net tec near zero. this type of glass - ceramic exhibits excellent mechanical properties and can sustain repeated and quick temperature changes up to 1000 °c. = = processing steps = = the traditional ceramic process generally follows this sequence : milling → batching → mixing → forming → drying → firing → assembly. milling is the process by which materials are reduced from a large size to a smaller size. milling may involve breaking up cemented material ( in which case individual particles retain their shape ) or pulverization ( which involves grinding the particles themselves to a smaller size ). milling is generally done by mechanical means, including attrition ( which is particle - to - particle collision that results in agglomerate break up or particle shearing ), compression ( which applies a forces that results in fracturing ), and impact ( which employs a milling medium or the particles themselves to cause fracturing ). attrition milling equipment includes the wet scrubber ( also called the planetary mill or wet attrition mill ), which has paddles in water creating vortexes in which Question: Magma can be created when temperature rises, pressure lowers, or what else is added? A) water B) dirt C) air D) sand	A) water
Context: fluid dynamics video demonstrating the evolution of dynamic stall on a wind turbine blade. the classical and the quantum motion of a massive body in the rotating tube is considered. photon is included. the spin motion described by the bargmann - michel - telegdi equation is considered in the rotation tube and rotating system. the kinematic moment of inertia of the rare earth even - even nuclei was calculated using three parametric energy based expression. the plot of kinematic moment of inertia versus nuclear spin shows a better sensitivity to back bending than energy plot. any two generating systems of the fundamental group of a closed surface are nielsen equivalent. an alternative explanation of 1 / f - noise in manganites is suggested and discussed in the muon storage rings the muons are subject to a very large radial acceleration. the equivalence principle implies a large gravity force. it has no effect on the muon lifetime. the curvature radiation is applied to the explain the circular polarization of frbs. significant circular polarization is reported in both apparently non - repeating and repeating frbs. curvature radiation can produce significant circular polarization at the wing of the radiation beam. in the curvature radiation scenario, in order to see significant circular polarization in frbs ( 1 ) more energetic bursts, ( 2 ) burst with electrons having higher lorentz factor, ( 3 ) a slowly rotating neutron star at the centre are required. different rotational period of the central neutron star may explain why some frbs have high circular polarization, while others don ' t. considering possible difference in refractive index for the parallel and perpendicular component of electric field, the position angle may change rapidly over the narrow pulse window of the radiation beam. the position angle swing in frbs may also be explained by this non - geometric origin, besides that of the rotating vector model. was done using the spinning wheel and weaving was done on a hand - and - foot - operated loom. it took from three to five spinners to supply one weaver. the invention of the flying shuttle in 1733 doubled the output of a weaver, creating a shortage of spinners. the spinning frame for wool was invented in 1738. the spinning jenny, invented in 1764, was a machine that used multiple spinning wheels ; however, it produced low quality thread. the water frame patented by richard arkwright in 1767, produced a better quality thread than the spinning jenny. the spinning mule, patented in 1779 by samuel crompton, produced a high quality thread. the power loom was invented by edmund cartwright in 1787. in the mid - 1750s, the steam engine was applied to the water power - constrained iron, copper and lead industries for powering blast bellows. these industries were located near the mines, some of which were using steam engines for mine pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, generation times. corn has been used to study mechanisms of photosynthesis and phloem loading of sugar in c4 plants. the single celled green alga chlamydomonas reinhardtii, while not an embryophyte itself, contains a green - pigmented chloroplast related to that of land plants, making it useful for study. a red alga cyanidioschyzon merolae has also been used to study some basic chloroplast functions. spinach, peas, soybeans and a moss physcomitrella patens are commonly used to study plant cell biology. agrobacterium tumefaciens, a soil rhizosphere bacterium, can attach to plant cells and infect them with a callus - inducing ti plasmid by horizontal gene transfer, causing a callus infection called crown gall disease. schell and van montagu ( 1977 ) hypothesised that the ti plasmid could be a natural vector for introducing the nif gene responsible for nitrogen fixation in the root nodules of legumes and other plant species. today, genetic modification of the ti plasmid is one of the main techniques for introduction of transgenes to plants and the creation of genetically modified crops. = = = epigenetics = = = epigenetics is the study of heritable changes in gene function that cannot be explained by changes in the underlying dna sequence but cause the organism ' s genes to behave ( or " express themselves " ) differently. one example of epigenetic change is the marking of the genes by dna methylation which determines whether they will be expressed or not. gene expression can also be controlled by repressor proteins that attach to silencer regions of the dna and prevent that region of the dna code from being expressed. epigenetic marks may be added or removed from the dna during programmed stages of development of the plant, and are responsible, for example, for the differences between anthers, petals and normal leaves, despite the fact that they all have the same underlying genetic code. epigenetic changes may be temporary or may remain through successive cell divisions for the remainder of the cell ' s life. some epigenetic changes have been shown to be heritable, while others are reset in the germ cells. epigenetic changes in eukaryotic biology serve to regulate the process of cellular differentiation. during morphogenesis, totipotent stem cells become the various parametric excitation of rotons by oscillating electric field exhibits a narrow resonance at the roton minimum frequency. the resonance width is in good agreement with experimental results on the microwave absorption in superfluid helium. Question: What is the rotational equivalent of a force? A) momentum B) torque C) power D) centripetal force	B) torque
Context: an antibody is to be generated. usually this is done by a series of injections of the antigen in question, over the course of several weeks. these injections are typically followed by the use of in vivo electroporation, which significantly enhances the immune response. once splenocytes are isolated from the mammal ' s spleen, the b cells are fused with immortalised myeloma cells. the fusion of the b cells with myeloma cells can be done using electrofusion. electrofusion causes the b cells and myeloma cells to align and fuse with the application of an electric field. alternatively, the b - cells and myelomas can be made to fuse by chemical protocols, most often using polyethylene glycol. the myeloma cells are selected beforehand to ensure they are not secreting antibody themselves and that they lack the hypoxanthine - guanine phosphoribosyltransferase ( hgprt ) gene, making them sensitive ( or vulnerable ) to the hat medium ( see below ). fused cells are incubated in hat medium ( hypoxanthine - aminopterin - thymidine medium ) for roughly 10 to 14 days. aminopterin blocks the pathway that allows for nucleotide synthesis. hence, unfused myeloma cells die, as they cannot produce nucleotides by the de novo or salvage pathways because they lack hgprt. removal of the unfused myeloma cells is necessary because they have the potential to outgrow other cells, especially weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then inc and myelomas can be made to fuse by chemical protocols, most often using polyethylene glycol. the myeloma cells are selected beforehand to ensure they are not secreting antibody themselves and that they lack the hypoxanthine - guanine phosphoribosyltransferase ( hgprt ) gene, making them sensitive ( or vulnerable ) to the hat medium ( see below ). fused cells are incubated in hat medium ( hypoxanthine - aminopterin - thymidine medium ) for roughly 10 to 14 days. aminopterin blocks the pathway that allows for nucleotide synthesis. hence, unfused myeloma cells die, as they cannot produce nucleotides by the de novo or salvage pathways because they lack hgprt. removal of the unfused myeloma cells is necessary because they have the potential to outgrow other cells, especially weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow ##se ( hgprt ) gene, making them sensitive ( or vulnerable ) to the hat medium ( see below ). fused cells are incubated in hat medium ( hypoxanthine - aminopterin - thymidine medium ) for roughly 10 to 14 days. aminopterin blocks the pathway that allows for nucleotide synthesis. hence, unfused myeloma cells die, as they cannot produce nucleotides by the de novo or salvage pathways because they lack hgprt. removal of the unfused myeloma cells is necessary because they have the potential to outgrow other cells, especially weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - s spleen, the b cells are fused with immortalised myeloma cells. the fusion of the b cells with myeloma cells can be done using electrofusion. electrofusion causes the b cells and myeloma cells to align and fuse with the application of an electric field. alternatively, the b - cells and myelomas can be made to fuse by chemical protocols, most often using polyethylene glycol. the myeloma cells are selected beforehand to ensure they are not secreting antibody themselves and that they lack the hypoxanthine - guanine phosphoribosyltransferase ( hgprt ) gene, making them sensitive ( or vulnerable ) to the hat medium ( see below ). fused cells are incubated in hat medium ( hypoxanthine - aminopterin - thymidine medium ) for roughly 10 to 14 days. aminopterin blocks the pathway that allows for nucleotide synthesis. hence, unfused myeloma cells die, as they cannot produce nucleotides by the de novo or salvage pathways because they lack hgprt. removal of the unfused myeloma cells is necessary because they have the potential to outgrow other cells, especially weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectromet for nucleotide synthesis. hence, unfused myeloma cells die, as they cannot produce nucleotides by the de novo or salvage pathways because they lack hgprt. removal of the unfused myeloma cells is necessary because they have the potential to outgrow other cells, especially weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, ##ry. immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. lifestyle medicine is the study of the chronic conditions, and how to prevent, treat and reverse them. medical physics is the study of the applications of physics principles in medicine. microbiology is the study of microorganisms, including protozoa, bacteria, fungi, and viruses. molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material. neuroscience includes those disciplines of science that are related to the study of the nervous system. a main focus of neuroscience is the biology and physiology of the human brain and spinal cord. some related clinical specialties include neurology, neurosurgery and psychiatry. nutrition science ( theoretical focus ) and dietetics ( practical focus ) is the study of the relationship of food and drink to health and disease, especially in determining an optimal diet. medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating disorders, allergies, malnutrition, and neoplastic diseases. pathology as a science is the study of disease – the causes, course, progression and resolution thereof. pharmacology is the study of drugs and their actions. photobiology is the study of the interactions between non - ionizing radiation and living organisms. physiology is the study of the normal functioning of the body and the underlying regulatory mechanisms. radiobiology is the study of the interactions between ionizing radiation and living organisms. toxicology is the study of hazardous effects of drugs and poisons. = = = specialties = = = in the broadest meaning of " medicine ", there are many different specialties. in the uk, most specialities have their own body or college, which has its own entrance examination. these are collectively known as the royal colleges, although not all currently use the term " royal ". the development of a speciality is often driven by new technology ( such as the development of effective anaesthetics ) or ways of working ( such as emergency departments ) ; the new specialty leads to the formation of a unifying body of doctors and the prestige of administering their own examination. within medical circles, specialities usually fit into one of two broad categories : " medicine " and " surgery ". " medicine " refers to the practice of non - operative medicine, and most of its subspecialties require preliminary training in internal medicine. in the uk weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - background : african swine fever is among the most devastating viral diseases of pigs. despite nearly a century of research, there is still no safe and effective vaccine available. the current situation is that either vaccines are safe but not effective, or they are effective but not safe. findings : the asf vaccine prepared using the inactivation method with propiolactone provided 98. 6 % protection within 100 days after three intranasal immunizations, spaced 7 days apart. conclusions : an inactivated vaccine made from complete african swine fever virus particles using propiolactone is safe and effective for controlling asf through mucosal immunity. listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, ##rates and peripheral blood, further development of this method is necessary before it can be used routinely. one major drawback of immuno - cytochemistry is that only tumor - associated and not tumor - specific monoclonal antibodies are used, and as a result, some cross - reaction with normal cells can occur. in order to effectively stage breast cancer and assess the efficacy of purging regimens prior to autologous stem cell infusion, it is important to detect even small quantities of breast cancer cells. immuno - histochemical methods are ideal for this purpose because they are simple, sensitive, and quite specific. franklin et al. performed a sensitive immuno - cytochemical assay by using a combination of four monoclonal antibodies ( 260f9, 520c9, 317g5 and bre - 3 ) against tumor cell surface glycoproteins to identify breast tumour cells in bone marrow and peripheral blood. they concluded from the results that immuno - cytochemical staining of bone marrow and peripheral blood is a sensitive and simple way to detect and quantify breast cancer cells. one of the main reasons for metastatic relapse in patients with solid tumours is the early dissemination of malignant cells. the use of monoclonal antibodies ( mabs ) specific for cytokeratins can identify disseminated individual epithelial tumor cells in the bone marrow. one study reports on having developed an immuno - cytochemical procedure for simultaneous labeling of cytokeratin component no. 18 ( ck18 ) and prostate specific antigen ( psa ). this would help in the further characterization of disseminated individual epithelial tumor cells in patients with prostate cancer. the twelve control aspirates from patients with benign prostatic hyperplasia showed negative staining, which further supports the specificity of ck18 in detecting epithelial tumour cells in bone marrow. in most cases of malignant disease complicated by effusion, neoplastic cells can be easily recognized. however, in some cases, malignant cells are not so easily seen or their presence is too doubtful to call it a positive report. the use of immuno - cytochemical techniques increases diagnostic accuracy in these cases. ghosh, mason and spriggs analysed 53 samples of pleural or peritoneal fluid from 41 patients with malignant disease. conventional cytological examination had not revealed any neoplastic cells. three monocl Question: What happens when when the immune system does not work properly? A) anemia B) diabetes C) stroke D) immunodeficiency	D) immunodeficiency
Context: techniques that provide heart and lung support. it is used primarily to support the lungs for a prolonged but still temporary timeframe ( 1 – 30 days ) and allow for recovery from reversible diseases. robert bartlett is known as the father of ecmo and performed the first treatment of a newborn using an ecmo machine in 1975. skin tissue - engineered skin is a type of bioartificial organ that is often used to treat burns, diabetic foot ulcers, or other large wounds that cannot heal well on their own. artificial skin can be made from autografts, allografts, and xenografts. autografted skin comes from a patient ' s own skin, which allows the dermis to have a faster healing rate, and the donor site can be re - harvested a few times. allograft skin often comes from cadaver skin and is mostly used to treat burn victims. lastly, xenografted skin comes from animals and provides a temporary healing structure for the skin. they assist in dermal regeneration, but cannot become part of the host skin. tissue - engineered skin is now available in commercial products. integra, originally used to only treat burns, consists of a collagen matrix and chondroitin sulfate that can be used as a skin replacement. the chondroitin sulfate functions as a component of proteoglycans, which helps to form the extracellular matrix. integra can be repopulated and revascularized while maintaining its dermal collagen architecture, making it a bioartificial organ dermagraft, another commercial - made tissue - engineered skin product, is made out of living fibroblasts. these fibroblasts proliferate and produce growth factors, collagen, and ecm proteins, that help build granulation tissue. = = = = heart = = = = since the number of patients awaiting a heart transplant is continuously increasing over time, and the number of patients on the waiting list surpasses the organ availability, artificial organs used as replacement therapy for terminal heart failure would help alleviate this difficulty. artificial hearts are usually used to bridge the heart transplantation or can be applied as replacement therapy for terminal heart malfunction. the total artificial heart ( tah ), first introduced by dr. vladimir p. demikhov in 1937, emerged as an ideal alternative. since then it has been developed and improved as a mechanical pump that provides long - term circulatory support and ##fts. autografted skin comes from a patient ' s own skin, which allows the dermis to have a faster healing rate, and the donor site can be re - harvested a few times. allograft skin often comes from cadaver skin and is mostly used to treat burn victims. lastly, xenografted skin comes from animals and provides a temporary healing structure for the skin. they assist in dermal regeneration, but cannot become part of the host skin. tissue - engineered skin is now available in commercial products. integra, originally used to only treat burns, consists of a collagen matrix and chondroitin sulfate that can be used as a skin replacement. the chondroitin sulfate functions as a component of proteoglycans, which helps to form the extracellular matrix. integra can be repopulated and revascularized while maintaining its dermal collagen architecture, making it a bioartificial organ dermagraft, another commercial - made tissue - engineered skin product, is made out of living fibroblasts. these fibroblasts proliferate and produce growth factors, collagen, and ecm proteins, that help build granulation tissue. = = = = heart = = = = since the number of patients awaiting a heart transplant is continuously increasing over time, and the number of patients on the waiting list surpasses the organ availability, artificial organs used as replacement therapy for terminal heart failure would help alleviate this difficulty. artificial hearts are usually used to bridge the heart transplantation or can be applied as replacement therapy for terminal heart malfunction. the total artificial heart ( tah ), first introduced by dr. vladimir p. demikhov in 1937, emerged as an ideal alternative. since then it has been developed and improved as a mechanical pump that provides long - term circulatory support and replaces diseased or damaged heart ventricles that cannot properly pump the blood, restoring thus the pulmonary and systemic flow. some of the current tahs include abiocor, an fda - approved device that comprises two artificial ventricles and their valves, and does not require subcutaneous connections, and is indicated for patients with biventricular heart failure. in 2010 syncardia released the portable freedom driver that allows patients to have a portable device without being confined to the hospital. = = = = kidney = = = = while kidney transplants are possible, renal failure is more often treated using an artificial kidney. the first artificial sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, 1975. skin tissue - engineered skin is a type of bioartificial organ that is often used to treat burns, diabetic foot ulcers, or other large wounds that cannot heal well on their own. artificial skin can be made from autografts, allografts, and xenografts. autografted skin comes from a patient ' s own skin, which allows the dermis to have a faster healing rate, and the donor site can be re - harvested a few times. allograft skin often comes from cadaver skin and is mostly used to treat burn victims. lastly, xenografted skin comes from animals and provides a temporary healing structure for the skin. they assist in dermal regeneration, but cannot become part of the host skin. tissue - engineered skin is now available in commercial products. integra, originally used to only treat burns, consists of a collagen matrix and chondroitin sulfate that can be used as a skin replacement. the chondroitin sulfate functions as a component of proteoglycans, which helps to form the extracellular matrix. integra can be repopulated and revascularized while maintaining its dermal collagen architecture, making it a bioartificial organ dermagraft, another commercial - made tissue - engineered skin product, is made out of living fibroblasts. these fibroblasts proliferate and produce growth factors, collagen, and ecm proteins, that help build granulation tissue. = = = = heart = = = = since the number of patients awaiting a heart transplant is continuously increasing over time, and the number of patients on the waiting list surpasses the organ availability, artificial organs used as replacement therapy for terminal heart failure would help alleviate this difficulty. artificial hearts are usually used to bridge the heart transplantation or can be applied as replacement therapy for terminal heart malfunction. the total artificial heart ( tah ), first introduced by dr. vladimir p. demikhov in 1937, emerged as an ideal alternative. since then it has been developed and improved as a mechanical pump that provides long - term circulatory support and replaces diseased or damaged heart ventricles that cannot properly pump the blood, restoring thus the pulmonary and systemic flow. some of the current tahs include abiocor, an fda - approved device that comprises two artificial ventricles and their valves, and does not require subcutaneous connections, and is indicated for within the military ranges from educational purposes, training exercises and sustainability technology. the technology used for educational purposes within the military are mainly wearables that tracks a soldier ' s vitals. by tracking a soldier ' s heart rate, blood pressure, emotional status, etc. helps the research and development team best help the soldiers. according to chemist, matt coppock, he has started to enhance a soldier ' s lethality by collecting different biorecognition receptors. by doing so it will eliminate emerging environmental threats to the soldiers. with the emergence of virtual reality it is only natural to start creating simulations using vr. this will better prepare the user for whatever situation they are training for. in the military there are combat simulations that soldiers will train on. the reason the military will use vr to train its soldiers is because it is the most interactive / immersive experience the user will feels without being put in a real situation. recent simulations include a soldier wearing a shock belt during a combat simulation. each time they are shot the belt will release a certain amount of electricity directly to the user ' s skin. this is to simulate a shot wound in the most humane way possible. there are many sustainability technologies that military personnel wear in the field. one of which is a boot insert. this insert gauges how soldiers are carrying the weight of their equipment and how daily terrain factors impact their mission panning optimization. these sensors will not only help the military plan the best timeline but will help keep the soldiers at best physical / mental health. = = fashion = = fashionable wearables are " designed garments and accessories that combines aesthetics and style with functional technology. " garments are the interface to the exterior mediated through digital technology. it allows endless possibilities for the dynamic customization of apparel. all clothes have social, psychological and physical functions. however, with the use of technology these functions can be amplified. there are some wearables that are called e - textiles. these are the combination of textiles ( fabric ) and electronic components to create wearable technology within clothing. they are also known as smart textile and digital textile. wearables are made from a functionality perspective or from an aesthetic perspective. when made from a functionality perspective, designers and engineers create wearables to provide convenience to the user. clothing and accessories are used as a tool to provide assistance to the user. designers and engineers are working together to incorporate technology in the manufacturing of garments in order to provide functionalities that can simplify the lives of the user. for example, through smartwatches a comparison of the sensitivities of methods which allow us to determine the coordinates of a moving hot body is made. you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), , social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary their mechanical properties. = = tissue culture = = in many cases, creation of functional tissues and biological structures in vitro requires extensive culturing to promote survival, growth and inducement of functionality. in general, the basic requirements of cells must be maintained in culture, which include oxygen, ph, humidity, temperature, nutrients and osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can ambient air ( see lockheed f - 117 nighthawk, rectangular nozzles on the lockheed martin f - 22 raptor, and serrated nozzle flaps on the lockheed martin f - 35 lightning ). often, cool air is deliberately injected into the exhaust flow to boost this process ( see ryan aqm - 91 firefly and northrop b - 2 spirit ). the stefan – boltzmann law shows how this results in less energy ( thermal radiation in infrared spectrum ) being released and thus reduces the heat signature. in some aircraft, the jet exhaust is vented above the wing surface to shield it from observers below, as in the lockheed f - 117 nighthawk, and the unstealthy fairchild republic a - 10 thunderbolt ii. to achieve infrared stealth, the exhaust gas is cooled to the temperatures where the brightest wavelengths it radiates are absorbed by atmospheric carbon dioxide and water vapor, greatly reducing the infrared visibility of the exhaust plume. another way to reduce the exhaust temperature is to circulate coolant fluids such as fuel inside the exhaust pipe, where the fuel tanks serve as heat sinks cooled by the flow of air along the wings. ground combat includes the use of both active and passive infrared sensors. thus, the united states marine corps ( usmc ) ground combat uniform requirements document specifies infrared reflective quality standards. = = reducing radio frequency ( rf ) emissions = = in addition to reducing infrared and acoustic emissions, a stealth vehicle must avoid radiating any other detectable energy, such as from onboard radars, communications systems, or rf leakage from electronics enclosures. the f - 117 uses passive infrared and low light level television sensor systems to aim its weapons and the f - 22 raptor has an advanced lpi radar which can illuminate enemy aircraft without triggering a radar warning receiver response. = = measuring = = the size of a target ' s image on radar is measured by the rcs, often represented by the symbol σ and expressed in square meters. this does not equal geometric area. a perfectly conducting sphere of projected cross sectional area 1 m2 ( i. e. a diameter of 1. 13 m ) will have an rcs of 1 m2. note that for radar wavelengths much less than the diameter of the sphere, rcs is independent of frequency. conversely, a square flat plate of area 1 m2 will have an rcs of σ = 4π a2 / λ2 ( where a = area, λ = wavelength ), or 13, 982 m2 at 10 ghz if the radar is perpendicular to the flat Question: What is the beneficial function to the body of sweating? A) regulating body temperature B) calorie loss C) diuretic effect D) pheromone release	A) regulating body temperature
Context: classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filtration behavior and selectivity. the selectivity is highly dependent on the separation process, the composition of the membrane and its electrochemical properties in addition to the pore size. with high selectivity, isotopes can be enriched ( uranium enrichment ) in nuclear engineering or industrial gases like nitrogen can be recovered ( gas separation ). ideally, even racemics can be enriched with a suitable membrane. when choosing membranes selectivity has priority over a high permeability, as low flows can easily be offset by increasing the filter surface with a modular structure. in gas phase filtration different deposition mechanisms are operative, so that particles having sizes below the pore size of the membrane can be retained as well. = = membrane classification = = bio - membrane is classified in two categories, synthetic membrane and natural membrane. synthetic membranes further classified in organic and inorganic membranes. organic membrane sub classified polymeric membranes and inorganic membrane sub classified ceramic polymers. = = synthesis of biomass membrane . most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell, there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support intense research in the materials science community due to the unique properties that they exhibit. nanostructure deals with objects and structures that are in the 1 – 100 nm range. in many materials, atoms or molecules agglomerate to form objects at the nanoscale. this causes many interesting electrical, magnetic, optical, and mechanical properties. in describing nanostructures, it is necessary to differentiate between the number of dimensions on the nanoscale. nanotextured surfaces have one dimension on the nanoscale, i. e., only the thickness of the surface of an object is between 0. 1 and 100 nm. nanotubes have two dimensions on the nanoscale, i. e., the diameter of the tube is between 0. 1 and 100 nm ; its length could be much greater. finally, spherical nanoparticles have three dimensions on the nanoscale, i. e., the particle is between 0. 1 and 100 nm in each spatial dimension. the terms nanoparticles and ultrafine particles ( ufp ) often are used synonymously although ufp can reach into the micrometre range. the term ' nanostructure ' is often used, when referring to magnetic technology. nanoscale structure in biology is often called ultrastructure. = = = = microstructure = = = = microstructure is defined as the structure of a prepared surface or thin foil of material as revealed by a microscope above 25× magnification. it deals with objects from 100 nm to a few cm. the microstructure of a material ( which can be broadly classified into metallic, polymeric, ceramic and composite ) can strongly influence physical properties such as strength, toughness, ductility, hardness, corrosion resistance, high / low temperature behavior, wear resistance, and so on. most of the traditional materials ( such as metals and ceramics ) are microstructured. the manufacture of a perfect crystal of a material is physically impossible. for example, any crystalline material will contain defects such as precipitates, grain boundaries ( hall – petch relationship ), vacancies, interstitial atoms or substitutional atoms. the microstructure of materials reveals these larger defects and advances in simulation have allowed an increased understanding of how defects can be used to enhance material properties. = = = = macrostructure = = = = macrostructure is the appearance of a material in the scale millimeters to meters, it is the structure of it is hard for us humans to recognize things in nature until we have invented them ourselves. for image - forming optics, nature has made virtually every kind of lens humans have devised. but what about lensless " imaging "? recently, we showed that a bare array of sensors on a curved substrate could achieve resolution not limited by diffraction - without any lens at all provided that the objects imaged conform to our a priori assumptions. is it possible that somewhere in nature we will find this kind of vision system? we think so and provide examples that seem to make no sense whatever unless they are using something like our lensless imaging work. generated by large populations of neurons in the cortex by placing a series of electrodes on the scalp of the subject. this technique has an extremely high temporal resolution, but a relatively poor spatial resolution. functional magnetic resonance imaging. fmri measures the relative amount of oxygenated blood flowing to different parts of the brain. more oxygenated blood in a particular region is assumed to correlate with an increase in neural activity in that part of the brain. this allows us to localize particular functions within different brain regions. fmri has moderate spatial and temporal resolution. optical imaging. this technique uses infrared transmitters and receivers to measure the amount of light reflectance by blood near different areas of the brain. since oxygenated and deoxygenated blood reflects light by different amounts, we can study which areas are more active ( i. e., those that have more oxygenated blood ). optical imaging has moderate temporal resolution, but poor spatial resolution. it also has the advantage that it is extremely safe and can be used to study infants ' brains. magnetoencephalography. meg measures magnetic fields resulting from cortical activity. it is similar to eeg, except that it has improved spatial resolution since the magnetic fields it measures are not as blurred or attenuated by the scalp, meninges and so forth as the electrical activity measured in eeg is. meg uses squid sensors to detect tiny magnetic fields. = = = computational modeling = = = computational models require a mathematically and logically formal representation of a problem. computer models are used in the simulation and experimental verification of different specific and general properties of intelligence. computational modeling can help us understand the functional organization of a particular cognitive phenomenon. approaches to cognitive modeling can be categorized as : ( 1 ) symbolic, on abstract mental functions of an intelligent mind by means of symbols ; ( 2 ) subsymbolic, on the neural and associative properties of the human brain ; and ( 3 ) across the symbolic – subsymbolic border, including hybrid. symbolic modeling evolved from the computer science paradigms using the technologies of knowledge - based systems, as well as a philosophical perspective ( e. g. " good old - fashioned artificial intelligence " ( gofai ) ). they were developed by the first cognitive researchers and later used in information engineering for expert systems. since the early 1990s it was generalized in systemics for the investigation of functional human - like intelligence models, such as personoids, and, in parallel, developed as the soar environment. recently, especially in scientists look through telescopes, study images on electronic screens, record meter readings, and so on. generally, on a basic level, they can agree on what they see, e. g., the thermometer shows 37. 9 degrees c. but, if these scientists have different ideas about the theories that have been developed to explain these basic observations, they may disagree about what they are observing. for example, before albert einstein ' s general theory of relativity, observers would have likely interpreted an image of the einstein cross as five different objects in space. in light of that theory, however, astronomers will tell you that there are actually only two objects, one in the center and four different images of a second object around the sides. alternatively, if other scientists suspect that something is wrong with the telescope and only one object is actually being observed, they are operating under yet another theory. observations that cannot be separated from theoretical interpretation are said to be theory - laden. all observation involves both perception and cognition. that is, one does not make an observation passively, but rather is actively engaged in distinguishing the phenomenon being observed from surrounding sensory data. therefore, observations are affected by one ' s underlying understanding of the way in which the world functions, and that understanding may influence what is perceived, noticed, or deemed worthy of consideration. in this sense, it can be argued that all observation is theory - laden. = = = the purpose of science = = = should science aim to determine ultimate truth, or are there questions that science cannot answer? scientific realists claim that science aims at truth and that one ought to regard scientific theories as true, approximately true, or likely true. conversely, scientific anti - realists argue that science does not aim ( or at least does not succeed ) at truth, especially truth about unobservables like electrons or other universes. instrumentalists argue that scientific theories should only be evaluated on whether they are useful. in their view, whether theories are true or not is beside the point, because the purpose of science is to make predictions and enable effective technology. realists often point to the success of recent scientific theories as evidence for the truth ( or near truth ) of current theories. antirealists point to either the many false theories in the history of science, epistemic morals, the success of false modeling assumptions, or widely termed postmodern criticisms of objectivity as evidence against scientific realism. antirealists attempt to explain the success of scientific theories without reference to truth. some antirealists claim that scientific education, science, in fact the whole society, extensively use images. between us and the world are the visual displays. screens, small and large, individual or not, are everywhere. images are increasingly the 2d substrate of our virtual interaction with reality. however images will never support a complete representation of the reality. three - dimensional representations will not change that. images are primarily a spatial representation of our world dedicated to our sight. key aspects such as energy and the associated forces are not spatially materialized. in classical physics, interaction description is based on newton equations with trajectory and force as the dual central concepts. images can in real time show all aspects of trajectories but not the associated dynamical aspects described by forces and energies. contrary to the real world, the world of images opposes no constrain, nor resistance to our actions. only the physical quantities, that do not contain mass in their dimension can be satisfactory represented by images. often symbols such as arrows are introduced to visualize the force vectors. small category. any ordinal number can be seen as a category when viewed as an ordered set. any monoid ( any algebraic structure with a single associative binary operation and an identity element ) forms a small category with a single object x. ( here, x is any fixed set. ) the morphisms from x to x are precisely the elements of the monoid, the identity morphism of x is the identity of the monoid, and the categorical composition of morphisms is given by the monoid operation. several definitions and theorems about monoids may be generalized for categories. similarly any group can be seen as a category with a single object in which every morphism is invertible, that is, for every morphism f there is a morphism g that is both left and right inverse to f under composition. a morphism that is invertible in this sense is called an isomorphism. a groupoid is a category in which every morphism is an isomorphism. groupoids are generalizations of groups, group actions and equivalence relations. actually, in the view of category the only difference between groupoid and group is that a groupoid may have more than one object but the group must have only one. consider a topological space x and fix a base point x 0 { \ displaystyle x _ { 0 } } of x, then π 1 ( x, x 0 ) { \ displaystyle \ pi _ { 1 } ( x, x _ { 0 } ) } is the fundamental group of the topological space x and the base point x 0 { \ displaystyle x _ { 0 } }, and as a set it has the structure of group ; if then let the base point x 0 { \ displaystyle x _ { 0 } } runs over all points of x, and take the union of all π 1 ( x, x 0 ) { \ displaystyle \ pi _ { 1 } ( x, x _ { 0 } ) }, then the set we get has only the structure of groupoid ( which is called as the fundamental groupoid of x ) : two loops ( under equivalence relation of homotopy ) may not have the same base point so they cannot multiply with each other. in the language of category, this means here two morphisms may not have the same source object ( or target object, because in this case for any morphism the source object and the target object are same : the base point ) so 0. 1 and 100 nm in each spatial dimension. the terms nanoparticles and ultrafine particles ( ufp ) often are used synonymously although ufp can reach into the micrometre range. the term ' nanostructure ' is often used, when referring to magnetic technology. nanoscale structure in biology is often called ultrastructure. = = = = microstructure = = = = microstructure is defined as the structure of a prepared surface or thin foil of material as revealed by a microscope above 25× magnification. it deals with objects from 100 nm to a few cm. the microstructure of a material ( which can be broadly classified into metallic, polymeric, ceramic and composite ) can strongly influence physical properties such as strength, toughness, ductility, hardness, corrosion resistance, high / low temperature behavior, wear resistance, and so on. most of the traditional materials ( such as metals and ceramics ) are microstructured. the manufacture of a perfect crystal of a material is physically impossible. for example, any crystalline material will contain defects such as precipitates, grain boundaries ( hall – petch relationship ), vacancies, interstitial atoms or substitutional atoms. the microstructure of materials reveals these larger defects and advances in simulation have allowed an increased understanding of how defects can be used to enhance material properties. = = = = macrostructure = = = = macrostructure is the appearance of a material in the scale millimeters to meters, it is the structure of the material as seen with the naked eye. = = = properties = = = materials exhibit myriad properties, including the following. mechanical properties, see strength of materials chemical properties, see chemistry electrical properties, see electricity thermal properties, see thermodynamics optical properties, see optics and photonics magnetic properties, see magnetism the properties of a material determine its usability and hence its engineering application. = = = processing = = = synthesis and processing involves the creation of a material with the desired micro - nanostructure. a material cannot be used in industry if no economically viable production method for it has been developed. therefore, developing processing methods for materials that are reasonably effective and cost - efficient is vital to the field of materials science. different materials require different processing or synthesis methods. for example, the processing of metals has historically defined eras such as the bronze age and iron age and is studied under the branch of materials science named physical metallurgy. in gravitational lensing, the concept of optical depth assumes the lens is dark. several microlensing detections have now been made where the lens may be bright. relations are developed between apparent and absolute optical depth in the regime of the apparent and absolute brightness of the lens. an apparent optical depth through bright lenses is always less than the true, absolute optical depth. the greater the intrinsic brightness of the lens, the more likely it will be found nearer the source. Question: What type of microscope is used to see extremely small objects? A) X-ray microscope B) electron microscope C) optical microscope D) ultrasonic microscope	B) electron microscope
Context: electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. = = = = substance and mixture = = = = a chemical substance is a kind of matter with a definite composition and set of properties. a collection of substances is called a mixture. examples of mixtures are air and alloys. = = = = mole and amount of substance = = = = the mole is a unit of measurement that denotes an amount of substance ( also called chemical amount ). one mole is defined to contain exactly 6. 02214076×1023 particles ( atoms, molecules, ions, or electrons ), where the number of particles per mole is known as the avogadro constant. molar concentration is the amount of a particular substance per volume of solution, and is commonly reported in mol / dm3. = = = phase = = = in addition to the specific chemical properties that distinguish different chemical classifications, chemicals can exist in several phases. for the most part, the chemical classifications are independent of these bulk phase in 2023, 639, 300 people died in france, 35, 900 fewer than in 2022, a year of high mortality. over the last twenty years, from 2004 to 2023, january 3rd was the deadliest day, while august 15th was the least deadly one. elderly people die significantly less often in the summer. deaths are also less frequent on public holidays and sundays. finally, the risk of dying is higher on one ' s birthday, especially for young people. the structural components of cells. as a by - product of photosynthesis, plants release oxygen into the atmosphere, a gas that is required by nearly all living things to carry out cellular respiration. in addition, they are influential in the global carbon and water cycles and plant roots bind and stabilise soils, preventing soil erosion. plants are crucial to the future of human society as they provide food, oxygen, biochemicals, and products for people, as well as creating and preserving soil. historically, all living things were classified as either animals or plants and botany covered the study of all organisms not considered animals. botanists examine both the internal functions and processes within plant organelles, cells, tissues, whole plants, plant populations and plant communities. at each of these levels, a botanist may be concerned with the classification ( taxonomy ), phylogeny and evolution, structure ( anatomy and morphology ), or function ( physiology ) of plant life. the strictest definition of " plant " includes only the " land plants " or embryophytes, which include seed plants ( gymnosperms, including the pines, and flowering plants ) and the free - sporing cryptogams including ferns, clubmosses, liverworts, hornworts and mosses. embryophytes are multicellular eukaryotes descended from an ancestor that obtained its energy from sunlight by photosynthesis. they have life cycles with alternating haploid and diploid phases. the sexual haploid phase of embryophytes, known as the gametophyte, nurtures the developing diploid embryo sporophyte within its tissues for at least part of its life, even in the seed plants, where the gametophyte itself is nurtured by its parent sporophyte. other groups of organisms that were previously studied by botanists include bacteria ( now studied in bacteriology ), fungi ( mycology ) – including lichen - forming fungi ( lichenology ), non - chlorophyte algae ( phycology ), and viruses ( virology ). however, attention is still given to these groups by botanists, and fungi ( including lichens ) and photosynthetic protists are usually covered in introductory botany courses. palaeobotanists study ancient plants in the fossil record to provide information about the evolutionary history of plants. cyanobacteria, the first oxygen - releasing photosynthetic organisms on earth, are thought to have given rise to the molecular nitrogen is the most commonly assumed background gas that supports habitability on rocky planets. despite its chemical inertness, nitrogen molecule is broken by lightning, hot volcanic vents, and bolide impacts, and can be converted into soluble nitrogen compounds and then sequestered in the ocean. the very stability of nitrogen, and that of nitrogen - based habitability, is thus called into question. here we determine the lifetime of molecular nitrogen vis - a - vis aqueous sequestration, by developing a novel model that couples atmospheric photochemistry and oceanic chemistry. we find that hno, the dominant nitrogen compounds produced in anoxic atmospheres, is converted to n2o in the ocean, rather than oxidized to nitrites or nitrates as previously assumed. this n2o is then released back into the atmosphere and quickly converted to n2. we also find that the deposition rate of no is severely limited by the kinetics of the aqueous - phase reaction that converts no to nitrites in the ocean. putting these insights together, we conclude that the atmosphere must produce nitrogen species at least as oxidized as no2 and hno2 to enable aqueous sequestration. the lifetime of molecular nitrogen in anoxic atmospheres is determined to be > 1 billion years on temperate planets of both sun - like and m dwarf stars. this result upholds the validity of molecular nitrogen as a universal background gas on rocky planets. enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest layer. in all, the atmosphere is made up of about 78. 0 % nitrogen, 20. 9 % oxygen, and 0. 92 % argon, and small amounts of other gases including co2 and water vapor. water vapor and co2 cause the earth ' s atmosphere to catch and hold the sun ' s energy through the greenhouse effect. this makes earth ' s surface warm enough for liquid water and life. in addition to trapping heat, the atmosphere also protects living organisms by shielding the earth ' s surface from cosmic rays. the magnetic field — created by the internal motions of the core — produces the magnetosphere which protects earth ' s atmosphere from the solar wind. as the earth is 4. 5 billion years old, it would have lost its atmosphere by now if there were no protective magnetosphere. = = earth ' s magnetic field = = = = hydrology = = hydrology is the study of the hydrosphere and the movement of water on earth. it emphasizes the study of how humans use and interact with freshwater supplies. study of water ' s movement is closely related to geomorphology and other branches of earth science. applied hydrology involves engineering to maintain aquatic environments and distribute water supplies. subdisciplines of hydrology include oceanography, hydrogeology, ecohydrology, and glaciology. oceanography is the study of oceans. hydrogeology is the study of groundwater. it includes the mapping of groundwater supplies and the analysis of groundwater contaminants. applied hydrogeology seeks to prevent contamination of groundwater and mineral springs and make it available as drinking water. the earliest exploitation of groundwater resources dates back to 3000 bc, and hydrogeology as a science was developed by hydrologists beginning in the 17th century. ecohydrology is the study of ecological systems in the hydrosphere. it can be divided into the physical study of aquatic ecosystems and the in this article i explain in detail a method for making small amounts of liquid oxygen in the classroom if there is no access to a cylinder of compressed oxygen gas. i also discuss two methods for identifying the fact that it is liquid oxygen as opposed to liquid nitrogen. we have combined measurements of the kinematics, morphology, and oxygen abundance of the ionized gas in \ izw18, one of the most metal - poor galaxies known, to examine the star formation history and chemical mixing processes. the most abundant molecule in every organism. water is important to life because it is an effective solvent, capable of dissolving solutes such as sodium and chloride ions or other small molecules to form an aqueous solution. once dissolved in water, these solutes are more likely to come in contact with one another and therefore take part in chemical reactions that sustain life. in terms of its molecular structure, water is a small polar molecule with a bent shape formed by the polar covalent bonds of two hydrogen ( h ) atoms to one oxygen ( o ) atom ( h2o ). because the o – h bonds are polar, the oxygen atom has a slight negative charge and the two hydrogen atoms have a slight positive charge. this polar property of water allows it to attract other water molecules via hydrogen bonds, which makes water cohesive. surface tension results from the cohesive force due to the attraction between molecules at the surface of the liquid. water is also adhesive as it is able to adhere to the surface of any polar or charged non - water molecules. water is denser as a liquid than it is as a solid ( or ice ). this unique property of water allows ice to float above liquid water such as ponds, lakes, and oceans, thereby insulating the liquid below from the cold air above. water has the capacity to absorb energy, giving it a higher specific heat capacity than other solvents such as ethanol. thus, a large amount of energy is needed to break the hydrogen bonds between water molecules to convert liquid water into water vapor. as a molecule, water is not completely stable as each water molecule continuously dissociates into hydrogen and hydroxyl ions before reforming into a water molecule again. in pure water, the number of hydrogen ions balances ( or equals ) the number of hydroxyl ions, resulting in a ph that is neutral. = = = organic compounds = = = organic compounds are molecules that contain carbon bonded to another element such as hydrogen. with the exception of water, nearly all the molecules that make up each organism contain carbon. carbon can form covalent bonds with up to four other atoms, enabling it to form diverse, large, and complex molecules. for example, a single carbon atom can form four single covalent bonds such as in methane, two double covalent bonds such as in carbon dioxide ( co2 ), or a triple covalent bond such as in carbon monoxide ( co ). moreover, carbon can form very long chains of interconnecting carbon – carbon bonds such plasma etching should not be conflated with the use of the same term when referring to orientation - dependent etching. the source gas for the plasma usually contains small molecules rich in chlorine or fluorine. for instance, carbon tetrachloride ( ccl4 ) etches silicon and aluminium, and trifluoromethane etches silicon dioxide and silicon nitride. a plasma containing oxygen is used to oxidize ( " ash " ) photoresist and facilitate its removal. ion milling, or sputter etching, uses lower pressures, often as low as 10−4 torr ( 10 mpa ). it bombards the wafer with energetic ions of noble gases, often ar +, which knock atoms from the substrate by transferring momentum. because the etching is performed by ions, which approach the wafer approximately from one direction, this process is highly anisotropic. on the other hand, it tends to display poor selectivity. reactive - ion etching ( rie ) operates under conditions intermediate between sputter and plasma etching ( between 10−3 and 10−1 torr ). deep reactive - ion etching ( drie ) modifies the rie technique to produce deep, narrow features. in reactive - ion etching ( rie ), the substrate is placed inside a reactor, and several gases are introduced. a plasma is struck in the gas mixture using an rf power source, which breaks the gas molecules into ions. the ions accelerate towards, and react with, the surface of the material being etched, forming another gaseous material. this is known as the chemical part of reactive ion etching. there is also a physical part, which is similar to the sputtering deposition process. if the ions have high enough energy, they can knock atoms out of the material to be etched without a chemical reaction. it is a very complex task to develop dry etch processes that balance chemical and physical etching, since there are many parameters to adjust. by changing the balance it is possible to influence the anisotropy of the etching, since the chemical part is isotropic and the physical part highly anisotropic the combination can form sidewalls that have shapes from rounded to vertical. deep reactive ion etching ( drie ) is a special subclass of rie that is growing in popularity. in this process, etch depths of hundreds of micrometers are achieved with almost vertical sidewalls. the primary technology is based on the the nro - ovro co imaging survey showed that molecular gas was more concentrated to the central kiloparsec in barred spiral galaxies than in their unbarred counterparts. the result provided not only evidence for bar - driven gas transport but also estimates on the mean rate of gas transfer and lower limits to the lifetime of bars. other lines of evidence for the bar - driven transport of ism in spiral galaxies are summarized. they are complementary with each other. Question: What is the most prevalent gas in the atmosphere, but not the most vital for life? A) nitrogen B) oxygen C) carbon dioxide D) argon	A) nitrogen
Context: casting, foundry methods, blast furnace extraction, and electrolytic extraction are all part of the required knowledge of a materials engineer. often the presence, absence, or variation of minute quantities of secondary elements and compounds in a bulk material will greatly affect the final properties of the materials produced. for example, steels are classified based on 1 / 10 and 1 / 100 weight percentages of the carbon and other alloying elements they contain. thus, the extracting and purifying methods used to extract iron in a blast furnace can affect the quality of steel that is produced. solid materials are generally grouped into three basic classifications : ceramics, metals, and polymers. this broad classification is based on the empirical makeup and atomic structure of the solid materials, and most solids fall into one of these broad categories. an item that is often made from each of these materials types is the beverage container. the material types used for beverage containers accordingly provide different advantages and disadvantages, depending on the material used. ceramic ( glass ) containers are optically transparent, impervious to the passage of carbon dioxide, relatively inexpensive, and are easily recycled, but are also heavy and fracture easily. metal ( aluminum alloy ) is relatively strong, is a good barrier to the diffusion of carbon dioxide, and is easily recycled. however, the cans are opaque, expensive to produce, and are easily dented and punctured. polymers ( polyethylene plastic ) are relatively strong, can be optically transparent, are inexpensive and lightweight, and can be recyclable, but are not as impervious to the passage of carbon dioxide as aluminum and glass. = = = ceramics and glasses = = = another application of materials science is the study of ceramics and glasses, typically the most brittle materials with industrial relevance. many ceramics and glasses exhibit covalent or ionic - covalent bonding with sio2 ( silica ) as a fundamental building block. ceramics – not to be confused with raw, unfired clay – are usually seen in crystalline form. the vast majority of commercial glasses contain a metal oxide fused with silica. at the high temperatures used to prepare glass, the material is a viscous liquid which solidifies into a disordered state upon cooling. windowpanes and eyeglasses are important examples. fibers of glass are also used for long - range telecommunication and optical transmission. scratch resistant corning gorilla glass is a well - known example of the application of materials science to drastically improve the properties of common components. engineering ceramics are known for their stiffness and based on 1 / 10 and 1 / 100 weight percentages of the carbon and other alloying elements they contain. thus, the extracting and purifying methods used to extract iron in a blast furnace can affect the quality of steel that is produced. solid materials are generally grouped into three basic classifications : ceramics, metals, and polymers. this broad classification is based on the empirical makeup and atomic structure of the solid materials, and most solids fall into one of these broad categories. an item that is often made from each of these materials types is the beverage container. the material types used for beverage containers accordingly provide different advantages and disadvantages, depending on the material used. ceramic ( glass ) containers are optically transparent, impervious to the passage of carbon dioxide, relatively inexpensive, and are easily recycled, but are also heavy and fracture easily. metal ( aluminum alloy ) is relatively strong, is a good barrier to the diffusion of carbon dioxide, and is easily recycled. however, the cans are opaque, expensive to produce, and are easily dented and punctured. polymers ( polyethylene plastic ) are relatively strong, can be optically transparent, are inexpensive and lightweight, and can be recyclable, but are not as impervious to the passage of carbon dioxide as aluminum and glass. = = = ceramics and glasses = = = another application of materials science is the study of ceramics and glasses, typically the most brittle materials with industrial relevance. many ceramics and glasses exhibit covalent or ionic - covalent bonding with sio2 ( silica ) as a fundamental building block. ceramics – not to be confused with raw, unfired clay – are usually seen in crystalline form. the vast majority of commercial glasses contain a metal oxide fused with silica. at the high temperatures used to prepare glass, the material is a viscous liquid which solidifies into a disordered state upon cooling. windowpanes and eyeglasses are important examples. fibers of glass are also used for long - range telecommunication and optical transmission. scratch resistant corning gorilla glass is a well - known example of the application of materials science to drastically improve the properties of common components. engineering ceramics are known for their stiffness and stability under high temperatures, compression and electrical stress. alumina, silicon carbide, and tungsten carbide are made from a fine powder of their constituents in a process of sintering with a binder. hot pressing provides higher density material. chemical vapor deposition can place a film of a ceramic on another was used before copper smelting was known. copper smelting is believed to have originated when the technology of pottery kilns allowed sufficiently high temperatures. the concentration of various elements such as arsenic increase with depth in copper ore deposits and smelting of these ores yields arsenical bronze, which can be sufficiently work hardened to be suitable for making tools. bronze is an alloy of copper with tin ; the latter being found in relatively few deposits globally caused a long time to elapse before true tin bronze became widespread. ( see : tin sources and trade in ancient times ) bronze was a major advancement over stone as a material for making tools, both because of its mechanical properties like strength and ductility and because it could be cast in molds to make intricately shaped objects. bronze significantly advanced shipbuilding technology with better tools and bronze nails. bronze nails replaced the old method of attaching boards of the hull with cord woven through drilled holes. better ships enabled long - distance trade and the advance of civilization. this technological trend apparently began in the fertile crescent and spread outward over time. these developments were not, and still are not, universal. the three - age system does not accurately describe the technology history of groups outside of eurasia, and does not apply at all in the case of some isolated populations, such as the spinifex people, the sentinelese, and various amazonian tribes, which still make use of stone age technology, and have not developed agricultural or metal technology. these villages preserve traditional customs in the face of global modernity, exhibiting a remarkable resistance to the rapid advancement of technology. = = = = iron age = = = = before iron smelting was developed the only iron was obtained from meteorites and is usually identified by having nickel content. meteoric iron was rare and valuable, but was sometimes used to make tools and other implements, such as fish hooks. the iron age involved the adoption of iron smelting technology. it generally replaced bronze and made it possible to produce tools which were stronger, lighter and cheaper to make than bronze equivalents. the raw materials to make iron, such as ore and limestone, are far more abundant than copper and especially tin ores. consequently, iron was produced in many areas. it was not possible to mass manufacture steel or pure iron because of the high temperatures required. furnaces could reach melting temperature but the crucibles and molds needed for melting and casting had not been developed. steel could be produced by forging bloomery iron to reduce the carbon content in a in 1738. the spinning jenny, invented in 1764, was a machine that used multiple spinning wheels ; however, it produced low quality thread. the water frame patented by richard arkwright in 1767, produced a better quality thread than the spinning jenny. the spinning mule, patented in 1779 by samuel crompton, produced a high quality thread. the power loom was invented by edmund cartwright in 1787. in the mid - 1750s, the steam engine was applied to the water power - constrained iron, copper and lead industries for powering blast bellows. these industries were located near the mines, some of which were using steam engines for mine pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, notably by richard roberts and joseph whitworth. the development of interchangeable parts through what is now called the american system of manufacturing began in the firearms industry at the u. s. federal arsenals in the early 19th century, and became widely used by the end of the century. until the enlightenment era, little progress surface. ceramics such as alumina, boron carbide and silicon carbide have been used in bulletproof vests to repel small arms rifle fire. such plates are known commonly as ballistic plates. similar material is used to protect cockpits of some military aircraft, because of the low weight of the material. silicon nitride parts are used in ceramic ball bearings. their higher hardness means that they are much less susceptible to wear and can offer more than triple lifetimes. they also deform less under load meaning they have less contact with the bearing retainer walls and can roll faster. in very high speed applications, heat from friction during rolling can cause problems for metal bearings ; problems which are reduced by the use of ceramics. ceramics are also more chemically resistant and can be used in wet environments where steel bearings would rust. the major drawback to using ceramics is a significantly higher cost. in many cases their electrically insulating properties may also be valuable in bearings. in the early 1980s, toyota researched production of an adiabatic ceramic engine which can run at a temperature of over 6000 °f ( 3300 °c ). ceramic engines do not require a cooling system and hence allow a major weight reduction and therefore greater fuel efficiency. fuel efficiency of the engine is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = is collected and processed to extract valuable metals. ore bodies often contain more than one valuable metal. tailings of a previous process may be used as a feed in another process to extract a secondary product from the original ore. additionally, a concentrate may contain more than one valuable metal. that concentrate would then be processed to separate the valuable metals into individual constituents. = = metal and its alloys = = much effort has been placed on understanding iron – carbon alloy system, which includes steels and cast irons. plain carbon steels ( those that contain essentially only carbon as an alloying element ) are used in low - cost, high - strength applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales the valuable metals into individual constituents. = = metal and its alloys = = much effort has been placed on understanding iron – carbon alloy system, which includes steels and cast irons. plain carbon steels ( those that contain essentially only carbon as an alloying element ) are used in low - cost, high - strength applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales is a commonly used practice that helps better understand the metal ' s elasticity and plasticity for different applications and production processes. in a saltwater environment, most ferrous metals and some non - ferrous alloys corrode quickly. metals exposed to cold or cryogenic conditions may undergo a ductile to brittle made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caissons ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up material. silicon nitride parts are used in ceramic ball bearings. their higher hardness means that they are much less susceptible to wear and can offer more than triple lifetimes. they also deform less under load meaning they have less contact with the bearing retainer walls and can roll faster. in very high speed applications, heat from friction during rolling can cause problems for metal bearings ; problems which are reduced by the use of ceramics. ceramics are also more chemically resistant and can be used in wet environments where steel bearings would rust. the major drawback to using ceramics is a significantly higher cost. in many cases their electrically insulating properties may also be valuable in bearings. in the early 1980s, toyota researched production of an adiabatic ceramic engine which can run at a temperature of over 6000 °f ( 3300 °c ). ceramic engines do not require a cooling system and hence allow a major weight reduction and therefore greater fuel efficiency. fuel efficiency of the engine is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are Question: Why wouldn't a teakettle have an aluminum handle? A) it is magnetic B) it isn't washable C) it absorbs light D) it conducts heat	D) it conducts heat
Context: , followed by a medical interview and a physical examination. basic diagnostic medical devices ( e. g., stethoscope, tongue depressor ) are typically used. after examining for signs and interviewing for symptoms, the doctor may order medical tests ( e. g., blood tests ), take a biopsy, or prescribe pharmaceutical drugs or other therapies. differential diagnosis methods help to rule out conditions based on the information provided. during the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. the medical encounter is then documented in the medical record, which is a legal document in many jurisdictions. follow - ups may be shorter but follow the same general procedure, and specialists follow a similar process. the diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue. the components of the medical interview and encounter are : chief complaint ( cc ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history scientists look through telescopes, study images on electronic screens, record meter readings, and so on. generally, on a basic level, they can agree on what they see, e. g., the thermometer shows 37. 9 degrees c. but, if these scientists have different ideas about the theories that have been developed to explain these basic observations, they may disagree about what they are observing. for example, before albert einstein ' s general theory of relativity, observers would have likely interpreted an image of the einstein cross as five different objects in space. in light of that theory, however, astronomers will tell you that there are actually only two objects, one in the center and four different images of a second object around the sides. alternatively, if other scientists suspect that something is wrong with the telescope and only one object is actually being observed, they are operating under yet another theory. observations that cannot be separated from theoretical interpretation are said to be theory - laden. all observation involves both perception and cognition. that is, one does not make an observation passively, but rather is actively engaged in distinguishing the phenomenon being observed from surrounding sensory data. therefore, observations are affected by one ' s underlying understanding of the way in which the world functions, and that understanding may influence what is perceived, noticed, or deemed worthy of consideration. in this sense, it can be argued that all observation is theory - laden. = = = the purpose of science = = = should science aim to determine ultimate truth, or are there questions that science cannot answer? scientific realists claim that science aims at truth and that one ought to regard scientific theories as true, approximately true, or likely true. conversely, scientific anti - realists argue that science does not aim ( or at least does not succeed ) at truth, especially truth about unobservables like electrons or other universes. instrumentalists argue that scientific theories should only be evaluated on whether they are useful. in their view, whether theories are true or not is beside the point, because the purpose of science is to make predictions and enable effective technology. realists often point to the success of recent scientific theories as evidence for the truth ( or near truth ) of current theories. antirealists point to either the many false theories in the history of science, epistemic morals, the success of false modeling assumptions, or widely termed postmodern criticisms of objectivity as evidence against scientific realism. antirealists attempt to explain the success of scientific theories without reference to truth. some antirealists claim that scientific , or prescribe pharmaceutical drugs or other therapies. differential diagnosis methods help to rule out conditions based on the information provided. during the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. the medical encounter is then documented in the medical record, which is a legal document in many jurisdictions. follow - ups may be shorter but follow the same general procedure, and specialists follow a similar process. the diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue. the components of the medical interview and encounter are : chief complaint ( cc ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses . biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems. biostatistics is the application of statistics to biological fields in the broadest sense. a knowledge of biostatistics is essential in the planning, evaluation, and interpretation of medical research. it is also fundamental to epidemiology and evidence - based medicine. cytology is the microscopic study of individual cells. embryology is the study of the early development of organisms. endocrinology is the study of hormones and their effect throughout the body of animals. epidemiology is the study of the demographics of disease processes, and includes, but is not limited to, the study of epidemics. genetics is the study of genes, and their role in biological inheritance. gynecology is the study of female reproductive system. histology is the study of the structures of biological tissues by light microscopy, electron microscopy and immunohistochemistry. immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. lifestyle medicine is the study of the chronic conditions, and how to prevent, treat and reverse them. medical physics is the study of the applications of physics principles in medicine. microbiology is the study of microorganisms, including protozoa, bacteria, fungi, and viruses. molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material. neuroscience includes those disciplines of science that are related to the study of the nervous system. a main focus of neuroscience is the biology and physiology of the human brain and spinal cord. some related clinical specialties include neurology, neurosurgery and psychiatry. nutrition science ( theoretical focus ) and dietetics ( practical focus ) is the study of the relationship of food and drink to health and disease, especially in determining an optimal diet. medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating disorders, allergies, malnutrition, and neoplastic diseases. pathology as a science is the study of disease – the causes, course, progression and resolution thereof. pharmacology is the study of drugs and their actions. photobiology is the study of the interactions between non - ionizing radiation and living organisms. physiology is the study of the normal functioning of the body and the underlying regulatory mechanisms. radiobiology is the study of the interactions between ionizing radiation and living organisms. interventions lacked sufficient evidence to support either benefit or harm. in modern clinical practice, physicians and physician assistants personally assess patients to diagnose, prognose, treat, and prevent disease using clinical judgment. the doctor - patient relationship typically begins with an interaction with an examination of the patient ' s medical history and medical record, followed by a medical interview and a physical examination. basic diagnostic medical devices ( e. g., stethoscope, tongue depressor ) are typically used. after examining for signs and interviewing for symptoms, the doctor may order medical tests ( e. g., blood tests ), take a biopsy, or prescribe pharmaceutical drugs or other therapies. differential diagnosis methods help to rule out conditions based on the information provided. during the encounter, properly informing the patient of all relevant facts is an important part of the relationship and the development of trust. the medical encounter is then documented in the medical record, which is a legal document in many jurisdictions. follow - ups may be shorter but follow the same general procedure, and specialists follow a similar process. the diagnosis and treatment may take only a few minutes or a few weeks, depending on the complexity of the issue. the components of the medical interview and encounter are : chief complaint ( cc ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have chemistry is the scientific study of the properties and behavior of matter. it is a physical science within the natural sciences that studies the chemical elements that make up matter and compounds made of atoms, molecules and ions : their composition, structure, properties, behavior and the changes they undergo during reactions with other substances. chemistry also addresses the nature of chemical bonds in chemical compounds. in the scope of its subject, chemistry occupies an intermediate position between physics and biology. it is sometimes called the central science because it provides a foundation for understanding both basic and applied scientific disciplines at a fundamental level. for example, chemistry explains aspects of plant growth ( botany ), the formation of igneous rocks ( geology ), how atmospheric ozone is formed and how environmental pollutants are degraded ( ecology ), the properties of the soil on the moon ( cosmochemistry ), how medications work ( pharmacology ), and how to collect dna evidence at a crime scene ( forensics ). chemistry has existed under various names since ancient times. it has evolved, and now chemistry encompasses various areas of specialisation, or subdisciplines, that continue to increase in number and interrelate to create further interdisciplinary fields of study. the applications of various fields of chemistry are used frequently for economic purposes in the chemical industry. = = etymology = = the word chemistry comes from a modification during the renaissance of the word alchemy, which referred to an earlier set of practices that encompassed elements of chemistry, metallurgy, philosophy, astrology, astronomy, mysticism, and medicine. alchemy is often associated with the quest to turn lead or other base metals into gold, though alchemists were also interested in many of the questions of modern chemistry. the modern word alchemy in turn is derived from the arabic word al - kimia ( الكیمیاء ). this may have egyptian origins since al - kimia is derived from the ancient greek χημια, which is in turn derived from the word kemet, which is the ancient name of egypt in the egyptian language. alternately, al - kimia may derive from χημεια ' cast together '. = = modern principles = = the current model of atomic structure is the quantum mechanical model. traditional chemistry starts with the study of elementary particles, atoms, molecules, substances, metals, crystals and other aggregates of matter. matter can be studied in solid, liquid, gas and plasma states, in isolation or in combination. the interactions, reactions and transformations that doing research is fighting, what any other thing the human being could do? fight against powers or to get powers, that depends on us. science can be a revolution or deadlocked idleness. still waters, without hitting the stones along their history, trend to form bogs. astronomy uses methods from astronomy to determine past celestial constellations for forensic purposes. forensic botany is the study of plant life in order to gain information regarding possible crimes. forensic chemistry is the study of detection and identification of illicit drugs, accelerants used in arson cases, explosive and gunshot residue. forensic dactyloscopy is the study of fingerprints. forensic document examination or questioned document examination answers questions about a disputed document using a variety of scientific processes and methods. many examinations involve a comparison of the questioned document, or components of the document, with a set of known standards. the most common type of examination involves handwriting, whereby the examiner tries to address concerns about potential authorship. forensic dna analysis takes advantage of the uniqueness of an individual ' s dna to answer forensic questions such as paternity / maternity testing and placing a suspect at a crime scene, e. g. in a rape investigation. forensic engineering is the scientific examination and analysis of structures and products relating to their failure or cause of damage. forensic entomology deals with the examination of insects in, on and around human remains to assist in determination of time or location of death. it is also possible to determine if the body was moved after death using entomology. forensic geology deals with trace evidence in the form of soils, minerals and petroleum. forensic geomorphology is the study of the ground surface to look for potential location ( s ) of buried object ( s ). forensic geophysics is the application of geophysical techniques such as radar for detecting objects hidden underground or underwater. forensic intelligence process starts with the collection of data and ends with the integration of results within into the analysis of crimes under investigation. forensic interviews are conducted using the science of professionally using expertise to conduct a variety of investigative interviews with victims, witnesses, suspects or other sources to determine the facts regarding suspicions, allegations or specific incidents in either public or private sector settings. forensic histopathology is the application of histological techniques and examination to forensic pathology practice. forensic limnology is the analysis of evidence collected from crime scenes in or around fresh - water sources. examination of biological organisms, in particular diatoms, can be useful in connecting suspects with victims. forensic linguistics deals with issues in the legal system that requires linguistic expertise. forensic meteorology is a site - specific analysis of past weather conditions for a point of loss. forensic metrology is the application of metrology to assess the reliability of scientific evidence obtained through measurements forensic microbiology is the study of the necrobiome. forensic nursing wounds or dead bodies should be examined, not avoided. the book became the first form of literature to help determine the cause of death. in one of song ci ' s accounts ( washing away of wrongs ), the case of a person murdered with a sickle was solved by an investigator who instructed each suspect to bring his sickle to one location. ( he realized it was a sickle by testing various blades on an animal carcass and comparing the wounds. ) flies, attracted by the smell of blood, eventually gathered on a single sickle. in light of this, the owner of that sickle confessed to the murder. the book also described how to distinguish between a drowning ( water in the lungs ) and strangulation ( broken neck cartilage ), and described evidence from examining corpses to determine if a death was caused by murder, suicide or accident. methods from around the world involved saliva and examination of the mouth and tongue to determine innocence or guilt, as a precursor to the polygraph test. in ancient india, some suspects were made to fill their mouths with dried rice and spit it back out. similarly, in ancient china, those accused of a crime would have rice powder placed in their mouths. in ancient middle - eastern cultures, the accused were made to lick hot metal rods briefly. it is thought that these tests had some validity since a guilty person would produce less saliva and thus have a drier mouth ; the accused would be considered guilty if rice was sticking to their mouths in abundance or if their tongues were severely burned due to lack of shielding from saliva. = = education and training = = initial glance, forensic intelligence may appear as a nascent facet of forensic science facilitated by advancements in information technologies such as computers, databases, and data - flow management software. however, a more profound examination reveals that forensic intelligence represents a genuine and emerging inclination among forensic practitioners to actively participate in investigative and policing strategies. in doing so, it elucidates existing practices within scientific literature, advocating for a paradigm shift from the prevailing conception of forensic science as a conglomerate of disciplines merely aiding the criminal justice system. instead, it urges a perspective that views forensic science as a discipline studying the informative potential of traces — remnants of criminal activity. embracing this transformative shift poses a significant challenge for education, necessitating a shift in learners ' mindset to accept concepts and methodologies in forensic intelligence. recent calls advocating for the integration of forensic scientists into the criminal justice system, as well as policing and intelligence missions, undersco not always mean it is required, especially when dealing with genetic or functional redundancy. tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. one way to do this is to replace the wild - type gene with a ' fusion ' gene, which is a juxtaposition of the wild - type gene with a reporting element such as green fluorescent protein ( gfp ) that will allow easy visualisation of the products of the genetic modification. while this is a useful technique, the manipulation can destroy the function of the gene, creating secondary effects and possibly calling into question the results of the experiment. more sophisticated techniques are now in development that can track protein products without mitigating their function, such as the addition of small sequences that will serve as binding motifs to monoclonal antibodies. expression studies aim to discover where and when specific proteins are produced. in these experiments, the dna sequence before the dna that codes for a protein, known as a gene ' s promoter, is reintroduced into an organism with the protein coding region replaced by a reporter gene such as gfp or an enzyme that catalyses the production of a dye. thus the time and place where a particular protein is produced can be observed. expression studies can be taken a step further by altering the promoter to find which pieces are crucial for the proper expression of the gene and are actually bound by transcription factor proteins ; this process is known as promoter bashing. = = = industrial = = = organisms can have their cells transformed with a gene coding for a useful protein, such as an enzyme, so that they will overexpress the desired protein. mass quantities of the protein can then be manufactured by growing the transformed organism in bioreactor equipment using industrial fermentation, and then purifying the protein. some genes do not work well in bacteria, so yeast, insect cells or mammalian cells can also be used. these techniques are used to produce medicines such as insulin, human growth hormone, and vaccines, supplements such as tryptophan, aid in the production of food ( chymosin in cheese making ) and fuels. other applications with genetically engineered bacteria could involve making them perform tasks outside their natural cycle, such as making biofuels, cleaning up oil spills, carbon and other toxic waste and detecting arsenic in drinking water. certain genetically modified microbes can also be used in biomining and bioremediation, due to their ability to extract heavy metals from their environment and incorporate them into compounds that are more easily recover Question: What can help scientist gather information for an investigation? A) controls B) variables C) conclusions D) observations	D) observations
Context: listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, christian emphasis on practical charity gave rise to the development of systematic nursing and hospitals, and the catholic church today remains the largest non - government provider of medical services in the world. advanced industrial countries ( with the exception of the united states ) and many developing countries provide medical services through a system of universal health care that aims to we cut the volume of surface code s gates by 25 % by omitting a hadamard gate. a watershed ( called a " divide " in north america ) over which rainfall flows down towards the river traversing the lowest part of the valley, whereas the rain falling on the far slope of the watershed flows away to another river draining an adjacent basin. river basins vary in extent according to the configuration of the country, ranging from the insignificant drainage areas of streams rising on high ground near the coast and flowing straight down into the sea, up to immense tracts of continents, where rivers rising on the slopes of mountain ranges far inland have to traverse vast stretches of valleys and plains before reaching the ocean. the size of the largest river basin of any country depends on the extent of the continent in which it is situated, its position in relation to the hilly regions in which rivers generally arise and the sea into which they flow, and the distance between the source and the outlet into the sea of the river draining it. the rate of flow of rivers depends mainly upon their fall, also known as the gradient or slope. when two rivers of different sizes have the same fall, the larger river has the quicker flow, as its retardation by friction against its bed and banks is less in proportion to its volume than is the case with the smaller river. the fall available in a section of a river approximately corresponds to the slope of the country it traverses ; as rivers rise close to the highest part of their basins, generally in hilly regions, their fall is rapid near their source and gradually diminishes, with occasional irregularities, until, in traversing plains along the latter part of their course, their fall usually becomes quite gentle. accordingly, in large basins, rivers in most cases begin as torrents with a variable flow, and end as gently flowing rivers with a comparatively regular discharge. the irregular flow of rivers throughout their course forms one of the main difficulties in devising works for mitigating inundations or for increasing the navigable capabilities of rivers. in tropical countries subject to periodical rains, the rivers are in flood during the rainy season and have hardly any flow during the rest of the year, while in temperate regions, where the rainfall is more evenly distributed throughout the year, evaporation causes the available rainfall to be much less in hot summer weather than in the winter months, so that the rivers fall to their low stage in the summer and are liable to be in flood in the winter. in fact, with a temperate climate, the year may be divided into a warm and a cold season, extending from may to october and from november to april in the northern above any tidal limit and their average freshwater discharge are proportionate to the extent of their basins and the amount of rain which, after falling over these basins, reaches the river channels in the bottom of the valleys, by which it is conveyed to the sea. the drainage basin of a river is the expanse of country bounded by a watershed ( called a " divide " in north america ) over which rainfall flows down towards the river traversing the lowest part of the valley, whereas the rain falling on the far slope of the watershed flows away to another river draining an adjacent basin. river basins vary in extent according to the configuration of the country, ranging from the insignificant drainage areas of streams rising on high ground near the coast and flowing straight down into the sea, up to immense tracts of continents, where rivers rising on the slopes of mountain ranges far inland have to traverse vast stretches of valleys and plains before reaching the ocean. the size of the largest river basin of any country depends on the extent of the continent in which it is situated, its position in relation to the hilly regions in which rivers generally arise and the sea into which they flow, and the distance between the source and the outlet into the sea of the river draining it. the rate of flow of rivers depends mainly upon their fall, also known as the gradient or slope. when two rivers of different sizes have the same fall, the larger river has the quicker flow, as its retardation by friction against its bed and banks is less in proportion to its volume than is the case with the smaller river. the fall available in a section of a river approximately corresponds to the slope of the country it traverses ; as rivers rise close to the highest part of their basins, generally in hilly regions, their fall is rapid near their source and gradually diminishes, with occasional irregularities, until, in traversing plains along the latter part of their course, their fall usually becomes quite gentle. accordingly, in large basins, rivers in most cases begin as torrents with a variable flow, and end as gently flowing rivers with a comparatively regular discharge. the irregular flow of rivers throughout their course forms one of the main difficulties in devising works for mitigating inundations or for increasing the navigable capabilities of rivers. in tropical countries subject to periodical rains, the rivers are in flood during the rainy season and have hardly any flow during the rest of the year, while in temperate regions, where the rainfall is more evenly distributed throughout the year, evaporation causes the available rainfall to be much less in hot summer all christian authors held that the earth was round. athenagoras, an eastern christian writing around the year 175 ad, said that the earth was spherical. methodius ( c. 290 ad ), an eastern christian writing against " the theory of the chaldeans and the egyptians " said : " let us first lay bare... the theory of the chaldeans and the egyptians. they say that the circumference of the universe is likened to the turnings of a well - rounded globe, the earth being a central point. they say that since its outline is spherical,... the earth should be the center of the universe, around which the heaven is whirling. " arnobius, another eastern christian writing sometime around 305 ad, described the round earth : " in the first place, indeed, the world itself is neither right nor left. it has neither upper nor lower regions, nor front nor back. for whatever is round and bounded on every side by the circumference of a solid sphere, has no beginning or end... " other advocates of a round earth included eusebius, hilary of poitiers, irenaeus, hippolytus of rome, firmicus maternus, ambrose, jerome, prudentius, favonius eulogius, and others. the only exceptions to this consensus up until the mid - fourth century were theophilus of antioch and lactantius, both of whom held anti - hellenistic views and associated the round - earth view with pagan cosmology. lactantius, a western christian writer and advisor to the first christian roman emperor, constantine, writing sometime between 304 and 313 ad, ridiculed the notion of antipodes and the philosophers who fancied that " the universe is round like a ball. they also thought that heaven revolves in accordance with the motion of the heavenly bodies.... for that reason, they constructed brass globes, as though after the figure of the universe. " the influential theologian and philosopher saint augustine, one of the four great church fathers of the western church, similarly objected to the " fable " of antipodes : but as to the fable that there are antipodes, that is to say, men on the opposite side of the earth, where the sun rises when it sets to us, men who walk with their feet opposite ours that is on no ground credible. and, indeed, it is not affirmed that this has been learned by historical knowledge, but by scientific conjecture sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures left no written records, the shift from nomadic life to settlement and agriculture can be inferred from a range of archaeological evidence. such evidence includes ancient tools, cave paintings, and other prehistoric art, such as the venus of willendorf. human remains also provide direct evidence, both through the examination of bones, and the study of mummies. scientists and historians have been able to form significant inferences about the lifestyle and culture of various prehistoric peoples, and especially their technology. = = = ancient = = = = = = = copper and bronze ages = = = = metallic copper occurs on the surface of weathered copper ore deposits and copper ##ate flux which is the volumetric flow rate per unit of membrane area. the solute sieving coefficient and hydraulic permeability allow the quick assessment of the synthetic membrane performance. = = membrane separation processes = = membrane separation processes have a very important role in the separation industry. nevertheless, they were not considered technically important until the mid - 1970s. membrane separation processes differ based on separation mechanisms and size of the separated particles. the widely used membrane processes include microfiltration, ultrafiltration, nanofiltration, reverse osmosis, electrolysis, dialysis, electrodialysis, gas separation, vapor permeation, pervaporation, membrane distillation, and membrane contactors. all processes except for pervaporation involve no phase change. all processes except electrodialysis are pressure driven. microfiltration and ultrafiltration is widely used in food and beverage processing ( beer microfiltration, apple juice ultrafiltration ), biotechnological applications and pharmaceutical industry ( antibiotic production, protein purification ), water purification and wastewater treatment, the microelectronics industry, and others. nanofiltration and reverse osmosis membranes are mainly used for water purification purposes. dense membranes are utilized for gas separations ( removal of co2 from natural gas, separating n2 from air, organic vapor removal from air or a nitrogen stream ) and sometimes in membrane distillation. the later process helps in the separation of azeotropic compositions reducing the costs of distillation processes. = = pore size and selectivity = = the pore sizes of technical membranes are specified differently depending on the manufacturer. one common distinction is by nominal pore size. it describes the maximum pore size distribution and gives only vague information about the retention capacity of a membrane. the exclusion limit or " cut - off " of the membrane is usually specified in the form of nmwc ( nominal molecular weight cut - off, or mwco, molecular weight cut off, with units in dalton ). it is defined as the minimum molecular weight of a globular molecule that is retained to 90 % by the membrane. the cut - off, depending on the method, can by converted to so - called d90, which is then expressed in a metric unit. in practice the mwco of the membrane should be at least 20 % lower than the molecular weight of the molecule that is to be separated. using track etched mica membranes beck and schultz demonstrated that hindered diffusion of molecules in pores can be described by the rankin equation. filter membranes are divided into four ##ning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures left no written records, the shift from nomadic life to settlement and agriculture can be inferred from a range of archaeological evidence. such evidence includes ancient tools, cave paintings, and other prehistoric art, such as the venus of willendorf. human remains also provide direct evidence, both through the examination of bones, and bare... the theory of the chaldeans and the egyptians. they say that the circumference of the universe is likened to the turnings of a well - rounded globe, the earth being a central point. they say that since its outline is spherical,... the earth should be the center of the universe, around which the heaven is whirling. " arnobius, another eastern christian writing sometime around 305 ad, described the round earth : " in the first place, indeed, the world itself is neither right nor left. it has neither upper nor lower regions, nor front nor back. for whatever is round and bounded on every side by the circumference of a solid sphere, has no beginning or end... " other advocates of a round earth included eusebius, hilary of poitiers, irenaeus, hippolytus of rome, firmicus maternus, ambrose, jerome, prudentius, favonius eulogius, and others. the only exceptions to this consensus up until the mid - fourth century were theophilus of antioch and lactantius, both of whom held anti - hellenistic views and associated the round - earth view with pagan cosmology. lactantius, a western christian writer and advisor to the first christian roman emperor, constantine, writing sometime between 304 and 313 ad, ridiculed the notion of antipodes and the philosophers who fancied that " the universe is round like a ball. they also thought that heaven revolves in accordance with the motion of the heavenly bodies.... for that reason, they constructed brass globes, as though after the figure of the universe. " the influential theologian and philosopher saint augustine, one of the four great church fathers of the western church, similarly objected to the " fable " of antipodes : but as to the fable that there are antipodes, that is to say, men on the opposite side of the earth, where the sun rises when it sets to us, men who walk with their feet opposite ours that is on no ground credible. and, indeed, it is not affirmed that this has been learned by historical knowledge, but by scientific conjecture, on the ground that the earth is suspended within the concavity of the sky, and that it has as much room on the one side of it as on the other : hence they say that the part that is beneath must also be inhabited. but they do not remark that, although it be supposed or scientifically Question: What do we call the region on the lung root formed by the entrance of the nerves at the hilum? A) renal plexus B) brain plexus C) heart plexus D) pulmonary plexus	D) pulmonary plexus
Context: ##trophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist frits went. the first known auxin, indole - 3 - acetic acid ( iaa ), which promotes cell growth, was only isolated from plants about 50 years later. this compound mediates the tropic responses of shoots and roots towards light and gravity. the finding in 1939 that plant callus slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for gly ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist ##logous in nature, and can be used in a myriad of ways, from helping repair skeletal tissue to replenishing beta cells in diabetic patients. allogenic : cells are obtained from the body of a donor of the same species as the recipient. while there are some ethical constraints to the use of human cells for in vitro studies ( i. e. human brain tissue chimera development ), the employment of dermal fibroblasts from human foreskin demonstrates an immunologically safe and thus a viable choice for allogenic tissue engineering of the skin. xenogenic : these cells are derived isolated cells from alternate species from the recipient. a notable example of xenogeneic tissue utilization is cardiovascular implant construction via animal cells. chimeric human - animal farming raises ethical concerns around the potential for improved consciousness from implanting human organs in animals. syngeneic or isogenic : these cells describe those borne from identical genetic code. this imparts an immunologic benefit similar to autologous cell lines ( see above ). autologous cells can be considered syngenic, but the classification also extends to non - autologously derived cells such as those from an identical twin, from genetically identical ( cloned ) research models, or induced stem cells ( isc ) as related to the donor. = = = stem cells = = = stem cells are undifferentiated cells with the ability to divide in culture and give rise to different forms of specialized cells. stem cells are divided into " adult " and " embryonic " stem cells according to their source. while there is still a large ethical debate related to the use of embryonic stem cells, it is thought that another alternative source – induced pluripotent stem cells – may be useful for the repair of diseased or damaged tissues, or may be used to grow new organs. totipotent cells are stem cells which can divide into further stem cells or differentiate into any cell type in the body, including extra - embryonic tissue. pluripotent cells are stem cells which can differentiate into any cell type in the body except extra - embryonic tissue. induced pluripotent stem cells ( ipscs ) are subclass of pluripotent stem cells resembling embryonic stem cells ( escs ) that have been derived from adult differentiated cells. ipscs are created by altering the expression of transcriptional factors in adult cells until they become like embryonic stem cells. multipotent stem cells can be differentiated into any cell oxygen ion migration in li2mno3 was systematically studied by first - principles calculations. hole polaron is found effective to lower the migration barrier of oxygen ion. release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist frits went. the first known auxin, indole - 3 - acetic acid ( iaa ), which promotes cell growth, was only isolated from plants about 50 years later. this compound mediates the tropic responses of shoots and roots towards light and gravity. the finding in 1939 that plant callus could be maintained in culture containing iaa, followed by the observation in 1947 that it could be induced to form roots and shoots by controlling the concentration of growth hormones were key steps in the development of plant biotechnology and genetic modification. cytokinins are a class of plant hormones named for their control of cell division ( especially wireless communication ( or just wireless, when the context allows ) is the transfer of information ( telecommunication ) between two or more points without the use of an electrical conductor, optical fiber or other continuous guided medium for the transfer. the most common wireless technologies use radio waves. with radio waves, intended distances can be short, such as a few meters for bluetooth, or as far as millions of kilometers for deep - space radio communications. it encompasses various types of fixed, mobile, and portable applications, including two - way radios, cellular telephones, personal digital assistants ( pdas ), and wireless networking. other examples of applications of radio wireless technology include gps units, garage door openers, wireless computer mouse, keyboards and headsets, headphones, radio receivers, satellite television, broadcast television and cordless telephones. somewhat less common methods of achieving wireless communications involve other electromagnetic phenomena, such as light and magnetic or electric fields, or the use of sound. the term wireless has been used twice in communications history, with slightly different meanings. it was initially used from about 1890 for the first radio transmitting and receiving technology, as in wireless telegraphy, until the new word radio replaced it around 1920. radio sets in the uk and the english - speaking world that were not portable continued to be referred to as wireless sets into the 1960s. the term wireless was revived in the 1980s and 1990s mainly to distinguish digital devices that communicate without wires, such as the examples listed in the previous paragraph, from those that require wires or cables. this became its primary usage in the 2000s, due to the advent of technologies such as mobile broadband, wi - fi, and bluetooth. wireless operations permit services, such as mobile and interplanetary communications, that are impossible or impractical to implement with the use of wires. the term is commonly used in the telecommunications industry to refer to telecommunications systems ( e. g. radio transmitters and receivers, remote controls, etc. ) that use some form of energy ( e. g. radio waves and acoustic energy ) to transfer information without the use of wires. information is transferred in this manner over both short and long distances. = = history = = = = = photophone = = = the first wireless telephone conversation occurred in 1880 when alexander graham bell and charles sumner tainter invented the photophone, a telephone that sent audio over a beam of light. the photophone required sunlight to operate, and a clear line of sight between the transmitter and receiver, which greatly decreased the viability of the photophone in any practical use nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of Question: Both oxygen and glucose are transported within the body via what? A) bone B) heart C) blood D) marrow	C) blood
Context: managing blood lipid levels is important for the treatment and prevention of diabetes, cardiovascular disease, and obesity. an easy - to - use, portable lipid blood test will accelerate more frequent testing by patients and at - risk populations. we used smartphone systems that are already familiar to many people. because smartphone systems can be carried around everywhere, blood can be measured easily and frequently. we compared the results of lipid tests with those of existing clinical diagnostic laboratory methods. we found that smartphone - based point - of - care lipid blood tests are as accurate as hospital - grade laboratory tests. our system will be useful for those who need to manage blood lipid levels to motivate them to track and control their behavior. required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthala by means of atomistic molecular dynamics simulations, we study cholesterol - dppc ( dipalmitoyl phosphatidylcholine ) bilayers of different composition, from pure dppc bilayers to a 1 : 1 mixture of dppc and cholesterol. the lateral - pressure profiles through the bilayers are computed and separated into contributions from the different components. we find that the pressure inside the bilayer changes qualitatively for cholesterol concentrations of about 20 % or higher. the pressure profile then turns from a rather flat shape into an alternating sequence of regions with large positive and negative lateral pressure. the changes in the lateral - pressure profile are so characteristic that specific interaction between cholesterol and molecules such as membrane proteins mediated solely via the lateral - pressure profile might become possible. and then graft healthy skin onto 80 percent of the boy ' s body which was affected by the illness. germline gene therapy would result in any change being inheritable, which has raised concerns within the scientific community. in 2015, crispr was used to edit the dna of non - viable human embryos, leading scientists of major world academies to call for a moratorium on inheritable human genome edits. there are also concerns that the technology could be used not just for treatment, but for enhancement, modification or alteration of a human beings ' appearance, adaptability, intelligence, character or behavior. the distinction between cure and enhancement can also be difficult to establish. in november 2018, he jiankui announced that he had edited the genomes of two human embryos, to attempt to disable the ccr5 gene, which codes for a receptor that hiv uses to enter cells. the work was widely condemned as unethical, dangerous, and premature. currently, germline modification is banned in 40 countries. scientists that do this type of research will often let embryos grow for a few days without allowing it to develop into a baby. researchers are altering the genome of pigs to induce the growth of human organs, with the aim of increasing the success of pig to human organ transplantation. scientists are creating " gene drives ", changing the genomes of mosquitoes to make them immune to malaria, and then looking to spread the genetically altered mosquitoes throughout the mosquito population in the hopes of eliminating the disease. = = = research = = = genetic engineering is an important tool for natural scientists, with the creation of transgenic organisms one of the most important tools for analysis of gene function. genes and other genetic information from a wide range of organisms can be inserted into bacteria for storage and modification, creating genetically modified bacteria in the process. bacteria are cheap, easy to grow, clonal, multiply quickly, relatively easy to transform and can be stored at - 80 °c almost indefinitely. once a gene is isolated it can be stored inside the bacteria providing an unlimited supply for research. organisms are genetically engineered to discover the functions of certain genes. this could be the effect on the phenotype of the organism, where the gene is expressed or what other genes it interacts with. these experiments generally involve loss of function, gain of function, tracking and expression. loss of function experiments, such as in a gene knockout experiment, in which an organism is engineered to lack the activity of one or more genes. in a simple knockout a copy the transversal and longitudinal resistance in the quantum hall effect regime was measured in a si mosfet sample in which a slot - gate allows one to vary the electron density and filling factor in different parts of the sample. in case of unequal gate voltages, the longitudinal resistances on the opposite sides of the sample differ from each other because the originated hall voltage difference is added to the longitudinal voltage only on one side depending on the gradient of the gate voltages and the direction of the external magnetic field. after subtracting the hall voltage difference, the increase in longitudinal resistance is observed when electrons on the opposite sides of the slot occupy landau levels with different spin orientations. osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. anemia is a major health burden worldwide. examining the hemoglobin level of blood is an important way to achieve the diagnosis of anemia, but it requires blood drawing and a blood test. in this work we propose a non - invasive, fast, and cost - effective screening test for iron - deficiency anemia in peruvian young children. our initial results show promising evidence for detecting conjunctival pallor anemia and artificial intelligence techniques with photos taken with a popular smartphone. tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively in future clinical stem cell therapies. mc2 biotek has also developed a bioreactor known as prototissue that uses gas exchange to maintain high oxygen levels within the cell chamber ; improving upon previous bioreactors, since the higher oxygen levels help the cell grow and undergo normal cell respiration. active areas of research on bioreactors includes increasing production scale and refining the physiological environment, both of which could improve the efficiency and efficacy of bioreactors in research or clinical use. bioreactors are currently used to study, among other things, cell and tissue level therapies, cell and tissue response to specific physiological environment changes, and development of disease and injury. = = = long fiber generation = = = in 2013, a group from the university of tokyo developed cell laden fibers up to a meter in length and on the order of 100 μm in size. these fibers were created using a microfluidic device that forms a double coaxial laminar flow. each ' layer ' of the microfluidic device ( cells seeded in ecm, a hydrogel sheath, and finally a calcium chloride solution ). the seeded cells culture within the hydrogel sheath for several days, and then the sheath is removed with viable cell fibers. various cell types were inserted into the ecm core, including myocytes, endothelial cells, nerve cell fibers, and epithelial cell fibers. this group then showed that these fibers can be woven together to fabricate tissues or organs in a mechanism similar to textile weaving. fibrous morphologies are advantageous in that they provide an alternative to traditional scaffold design, and many organs ( such as muscle ) are composed of fibrous cells. = = = bioartificial organs = = = an artificial organ is an engineered device that can be extra corporeal or implanted to support impaired or failing organ Question: An increase in the body's cholesterol levels can lead to your arteries filling with what? A) marble B) triglycerides C) fat D) plaque	D) plaque
Context: reaction to proceed more rapidly without being consumed by it — by reducing the amount of activation energy needed to convert reactants into products. enzymes also allow the regulation of the rate of a metabolic reaction, for example in response to changes in the cell ' s environment or to signals from other cells. = = = cellular respiration = = = cellular respiration is a set of metabolic reactions and processes that take place in cells to convert chemical energy from nutrients into adenosine triphosphate ( atp ), and then release waste products. the reactions involved in respiration are catabolic reactions, which break large molecules into smaller ones, releasing energy. respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. the overall reaction occurs in a series of biochemical steps, some of which are redox reactions. although cellular respiration is technically a combustion reaction, it clearly does not resemble one when it occurs in a cell because of the slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. , like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid in a predetermined sequence. after the control or power has been isolated, a key is released that can be used to grant access to individual or multiple doors. below is an example of what a trapped key interlock transfer block would look like. this is a part of a trapped key interlocking system. in order to obtain the keys in this system, a key must be inserted and turned ( like the key at the bottom of the system of the picture ). once the key is turned, the operator may retrieve the remaining keys that will be used to open other doors. once all keys are returned, then the operator will be allowed to take out the original key from the beginning. the key will not turn unless the remaining keys are put back in place. another example is an electric kiln. to prevent access to the inside of an electric kiln, a trapped key system may be used to interlock a disconnecting switch and the kiln door. while the switch is turned on, the key is held by the interlock attached to the disconnecting switch. to open the kiln door, the switch is first opened, which releases the key. the key can then be used to unlock the kiln door. while the key is removed from the switch interlock, a plunger from the interlock mechanically prevents the switch from closing. power cannot be re - applied to the kiln until the kiln door is locked, releasing the key, and the key is then returned to the disconnecting switch interlock. a similar two - part interlock system can be used anywhere it is necessary to ensure the energy supply to a machine is interrupted before the machine is entered for adjustment or maintenance. = = mechanical = = interlocks may be strictly mechanical. an example of a mechanical interlock is a steering wheel of a car. in modern days, most cars have an anti - theft feature that restricts the turning of the steering wheel if the key is not inserted in the ignition. this prevents an individual from pushing the car since the mechanical interlock restricts the directional motion of the front wheels of the car. in the operation of a device such as a press or cutter that is hand fed or the workpiece hand removed, the use of two buttons to actuate the device, one for each hand, greatly reduces the possibility of operation endangering the operator. no such system is fool - proof, and such systems are often augmented by the use of cable – pulled gloves worn by the operator ; these are . oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be ; however, a successful large - scale industrial application of the process was the development of continuous freeze drying of coffee. high - temperature short time processing – these processes, for the most part, are characterized by rapid heating and cooling, holding for a short time at a relatively high temperature and filling aseptically into sterile containers. decaffeination of coffee and tea – decaffeinated coffee and tea was first developed on a commercial basis in europe around 1900. the process is described in u. s. patent 897, 763. green coffee beans are treated with water, heat and solvents to remove the caffeine from the beans. process optimization – food technology now allows production of foods to be more efficient, oil saving technologies are now available on different forms. production methods and methodology have also become increasingly sophisticated. aseptic packaging – the process of filling a commercially sterile product into a sterile container and hermetically sealing the containers so that re - infection is prevented. thus, this results into a shelf stable product at ambient conditions. food irradiation – the process of exposing food and food packaging to ionizing radiation can effectively destroy organisms responsible for spoilage and foodborne illness and inhibit sprouting, extending shelf life. commercial fruit ripening rooms using ethylene as a plant hormone. food delivery – an order is typically made either through a restaurant or grocer ' s website or mobile app, or through a food ordering company. the ordered food is typically delivered in boxes or bags to the customer ' s doorsteps. = = categories = = technology has innovated these categories from the food industry : agricultural technology – or agtech, it is the use of technology in agriculture, horticulture, and aquaculture with the aim of improving yield, efficiency, and profitability. agricultural technology can be products, services or applications derived from agriculture that improve various input / output processes. food science – technology in this sector focuses on the development of new functional ingredients and alternative proteins. foodservice – technology innovated the way establishments prepare, supply, and serve food outside the home. there ' s a tendency to create the conditions for the restaurant of the future with robotics and cloudkitchens. consumer tech – technology allows what we call consumer electronics, which is the equipment of consumers with devices that facilitates the cooking process. food delivery – as the food delivery market is growing, companies and startups are rapidly revolutionizing the communication process between consumers and food establishments, with platform - to - consumer delivery as the oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for index chemical substances. in this scheme each chemical substance is identifiable by a number known as its cas registry number. = = = = molecule = = = = a molecule is the smallest indivisible portion of a pure chemical substance that has its unique set of chemical properties, that is, its potential to undergo a certain set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry Question: After citric acid forms, it goes through a series of reactions that release what, which is then captured in special molecules? A) hydrogen B) metabolytes C) energy D) chlorophyll	C) energy
Context: are studied in chemistry are usually the result of interactions between atoms, leading to rearrangements of the chemical bonds which hold atoms together. such behaviors are studied in a chemistry laboratory. the chemistry laboratory stereotypically uses various forms of laboratory glassware. however glassware is not central to chemistry, and a great deal of experimental ( as well as applied / industrial ) chemistry is done without it. a chemical reaction is a transformation of some substances into one or more different substances. the basis of such a chemical transformation is the rearrangement of electrons in the chemical bonds between atoms. it can be symbolically depicted through a chemical equation, which usually involves atoms as subjects. the number of atoms on the left and the right in the equation for a chemical transformation is equal. ( when the number of atoms on either side is unequal, the transformation is referred to as a nuclear reaction or radioactive decay. ) the type of chemical reactions a substance may undergo and the energy changes that may accompany it are constrained by certain basic rules, known as chemical laws. energy and entropy considerations are invariably important in almost all chemical studies. chemical substances are classified in terms of their structure, phase, as well as their chemical compositions. they can be analyzed using the tools of chemical analysis, e. g. spectroscopy and chromatography. scientists engaged in chemical research are known as chemists. most chemists specialize in one or more sub - disciplines. several concepts are essential for the study of chemistry ; some of them are : = = = matter = = = in chemistry, matter is defined as anything that has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = the atom is the basic unit of chemistry. it consists of a dense core called the atomic nucleus surrounded by a space occupied by an electron cloud. the nucleus is made up of positively charged protons and uncharged neutrons ( together called nucleons ), while the electron cloud consists of negatively charged electrons which orbit the nucleus. in a neutral atom, the negatively charged electrons balance out the positive charge of the protons. the nucleus is dense ; the mass of a nucleon is approximately 1, 836 times that of an electron, yet the radius of an atom is about 10, 000 times that of its nucleus. the atom analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( current model of atomic structure is the quantum mechanical model. traditional chemistry starts with the study of elementary particles, atoms, molecules, substances, metals, crystals and other aggregates of matter. matter can be studied in solid, liquid, gas and plasma states, in isolation or in combination. the interactions, reactions and transformations that are studied in chemistry are usually the result of interactions between atoms, leading to rearrangements of the chemical bonds which hold atoms together. such behaviors are studied in a chemistry laboratory. the chemistry laboratory stereotypically uses various forms of laboratory glassware. however glassware is not central to chemistry, and a great deal of experimental ( as well as applied / industrial ) chemistry is done without it. a chemical reaction is a transformation of some substances into one or more different substances. the basis of such a chemical transformation is the rearrangement of electrons in the chemical bonds between atoms. it can be symbolically depicted through a chemical equation, which usually involves atoms as subjects. the number of atoms on the left and the right in the equation for a chemical transformation is equal. ( when the number of atoms on either side is unequal, the transformation is referred to as a nuclear reaction or radioactive decay. ) the type of chemical reactions a substance may undergo and the energy changes that may accompany it are constrained by certain basic rules, known as chemical laws. energy and entropy considerations are invariably important in almost all chemical studies. chemical substances are classified in terms of their structure, phase, as well as their chemical compositions. they can be analyzed using the tools of chemical analysis, e. g. spectroscopy and chromatography. scientists engaged in chemical research are known as chemists. most chemists specialize in one or more sub - disciplines. several concepts are essential for the study of chemistry ; some of them are : = = = matter = = = in chemistry, matter is defined as anything that has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = the atom is the basic unit of chemistry. it consists of a dense core called the atomic nucleus surrounded by a space occupied by an electron cloud. the nucleus is made up of positively charged protons and uncharged neutrons ( together called nucleons ), while the electron cloud consists of negatively charged electrons which orbit the . oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants. a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. al - kimia is derived from the ancient greek χημια, which is in turn derived from the word kemet, which is the ancient name of egypt in the egyptian language. alternately, al - kimia may derive from χημεια ' cast together '. = = modern principles = = the current model of atomic structure is the quantum mechanical model. traditional chemistry starts with the study of elementary particles, atoms, molecules, substances, metals, crystals and other aggregates of matter. matter can be studied in solid, liquid, gas and plasma states, in isolation or in combination. the interactions, reactions and transformations that are studied in chemistry are usually the result of interactions between atoms, leading to rearrangements of the chemical bonds which hold atoms together. such behaviors are studied in a chemistry laboratory. the chemistry laboratory stereotypically uses various forms of laboratory glassware. however glassware is not central to chemistry, and a great deal of experimental ( as well as applied / industrial ) chemistry is done without it. a chemical reaction is a transformation of some substances into one or more different substances. the basis of such a chemical transformation is the rearrangement of electrons in the chemical bonds between atoms. it can be symbolically depicted through a chemical equation, which usually involves atoms as subjects. the number of atoms on the left and the right in the equation for a chemical transformation is equal. ( when the number of atoms on either side is unequal, the transformation is referred to as a nuclear reaction or radioactive decay. ) the type of chemical reactions a substance may undergo and the energy changes that may accompany it are constrained by certain basic rules, known as chemical laws. energy and entropy considerations are invariably important in almost all chemical studies. chemical substances are classified in terms of their structure, phase, as well as their chemical compositions. they can be analyzed using the tools of chemical analysis, e. g. spectroscopy and chromatography. scientists engaged in chemical research are known as chemists. most chemists specialize in one or more sub - disciplines. several concepts are essential for the study of chemistry ; some of them are : = = = matter = = = in chemistry, matter is defined as anything that has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws, which have become fundamental concepts in chemistry. some of them are : = = history = = the history of chemistry spans a period from the ancient past to the present. since several millennia bc, civilizations were using technologies that would eventually form the basis of the various branches of chemistry. examples include extracting metals from ores, making pottery and glazes, fermenting beer and wine, extracting chemicals from plants for medicine and perfume, rendering fat into soap, making glass, and making alloys like bronze. chemistry was preceded by its protoscience, alchemy, which operated a non - scientific approach to understanding the constituents of matter and their interactions. despite being unsuccessful in explaining the nature of matter and its transformations, alchemists set the stage for modern chemistry by performing experiments and recording the results. robert boyle, although skeptical of elements and convinced of alchemy, played a key part in elevating the " sacred art " as an Question: All chemical changes involve a transfer of what? A) energy B) nitrogen C) hydrogen D) pressure	A) energy
Context: or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, christian emphasis on practical charity gave rise to the development of systematic nursing and hospitals, and the catholic church today remains the largest non - government provider of medical services in the world. advanced industrial countries ( with the exception of the united states ) and many developing countries provide medical services through a system of universal health care that aims to scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws, which have become fundamental concepts in chemistry. some of them are : = = history = = the history of chemistry spans a period from the ancient past to the present. since several millennia bc, civilizations were using technologies that would eventually form the basis of the various branches of chemistry. examples include extracting metals from ores we reply to the comment arxiv : quant - ph / 0702060 on our letter arxiv : quant - ph / 0603120 [ phys. rev. lett. 96, 100402 ( 2006 ) ] an extended polya urn model with two colors, black and white, is studied with some slln and clt on the proportion of white balls. required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on oxygen ion migration in li2mno3 was systematically studied by first - principles calculations. hole polaron is found effective to lower the migration barrier of oxygen ion. ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. Question: The normal response of the respiratory system to elevated ph is to increase the amount of what in the blood? A) acid B) co2 C) glucose D) red blood cells	B) co2
Context: set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. = = = = substance and mixture = = = = a chemical substance is a kind of matter with a definite composition and set of properties. a collection of substances is called a mixture. examples of mixtures are air and alloys. = = = = mole and amount of substance = = = = the mole is a unit has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = the atom is the basic unit of chemistry. it consists of a dense core called the atomic nucleus surrounded by a space occupied by an electron cloud. the nucleus is made up of positively charged protons and uncharged neutrons ( together called nucleons ), while the electron cloud consists of negatively charged electrons which orbit the nucleus. in a neutral atom, the negatively charged electrons balance out the positive charge of the protons. the nucleus is dense ; the mass of a nucleon is approximately 1, 836 times that of an electron, yet the radius of an atom is about 10, 000 times that of its nucleus. the atom is also the smallest entity that can be envisaged to retain the chemical properties of the element, such as electronegativity, ionization potential, preferred oxidation state ( s ), coordination number, and preferred types of bonds to form ( e. g., metallic, ionic, covalent ). = = = = element = = = = a chemical element is a pure substance which is composed of a single type of atom, characterized by its particular number of protons in the nuclei of its atoms, known as the atomic number and represented by the symbol z. the mass number is the sum of the number of protons and neutrons in a nucleus. although all the nuclei of all atoms belonging to one element will have the same atomic number, they may not necessarily have the same mass number ; atoms of an element which have different mass numbers are known as isotopes. for example, all atoms with 6 protons in their nuclei are atoms of the chemical element carbon, but atoms of carbon may have mass numbers of 12 or 13. the standard presentation of the chemical elements is in the periodic table, which orders elements by atomic number. the periodic table is arranged in groups, or columns, and periods, or rows. the periodic table is useful in identifying periodic trends. = = = = compound = = = = a compound is a pure chemical substance composed of more than one element. the properties of a compound bear little similarity to those of its elements. the standard nomenclature of compounds is set by the international union of pure and applied chemistry ( iupac ). organic compounds are named to explain molecular structure and composition. an ionic bond is formed when a metal loses one or more of its electrons, becoming a positively charged cation, and the electrons are then gained by the non - metal atom, becoming a negatively charged anion. the two oppositely charged ions attract one another, and the ionic bond is the electrostatic force of attraction between them. for example, sodium ( na ), a metal, loses one electron to become an na + cation while chlorine ( cl ), a non - metal, gains this electron to become cl−. the ions are held together due to electrostatic attraction, and that compound sodium chloride ( nacl ), or common table salt, is formed. in a covalent bond, one or more pairs of valence electrons are shared by two atoms : the resulting electrically neutral group of bonded atoms is termed a molecule. atoms will share valence electrons in such a way as to create a noble gas electron configuration ( eight electrons in their outermost shell ) for each atom. atoms that tend to combine in such a way that they each have eight electrons in their valence shell are said to follow the octet rule. however, some elements like hydrogen and lithium need only two electrons in their outermost shell to attain this stable configuration ; these atoms are said to follow the duet rule, and in this way they are reaching the electron configuration of the noble gas helium, which has two electrons in its outer shell. similarly, theories from classical physics can be used to predict many ionic structures. with more complicated compounds, such as metal complexes, valence bond theory is less applicable and alternative approaches, such as the molecular orbital theory, are generally used. = = = energy = = = in the context of chemistry, energy is an attribute of a substance as a consequence of its atomic, molecular or aggregate structure. since a chemical transformation is accompanied by a change in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants. a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. according to brønsted – lowry acid – base theory, acids are substances that donate a positive hydrogen ion to another substance in a chemical reaction ; by extension, a base is the substance which receives that hydrogen ion. a third common theory is lewis acid – base theory, which is based on the formation of new chemical bonds. lewis theory explains that an acid is a substance which is capable of accepting a pair of electrons from another substance during the process of bond formation, while a base is a substance which can provide a pair of electrons to form a new bond. there are several other ways in which a substance may be classified as an acid or a base, as is evident in the history of this concept. acid strength is commonly measured by two methods. one measurement, based on the arrhenius definition of acidity, is ph, which is a measurement of the hydronium ion concentration in a solution, as expressed on a negative logarithmic scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their is the electrostatic force of attraction between them. for example, sodium ( na ), a metal, loses one electron to become an na + cation while chlorine ( cl ), a non - metal, gains this electron to become cl−. the ions are held together due to electrostatic attraction, and that compound sodium chloride ( nacl ), or common table salt, is formed. in a covalent bond, one or more pairs of valence electrons are shared by two atoms : the resulting electrically neutral group of bonded atoms is termed a molecule. atoms will share valence electrons in such a way as to create a noble gas electron configuration ( eight electrons in their outermost shell ) for each atom. atoms that tend to combine in such a way that they each have eight electrons in their valence shell are said to follow the octet rule. however, some elements like hydrogen and lithium need only two electrons in their outermost shell to attain this stable configuration ; these atoms are said to follow the duet rule, and in this way they are reaching the electron configuration of the noble gas helium, which has two electrons in its outer shell. similarly, theories from classical physics can be used to predict many ionic structures. with more complicated compounds, such as metal complexes, valence bond theory is less applicable and alternative approaches, such as the molecular orbital theory, are generally used. = = = energy = = = in the context of chemistry, energy is an attribute of a substance as a consequence of its atomic, molecular or aggregate structure. since a chemical transformation is accompanied by a change in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants. a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population index chemical substances. in this scheme each chemical substance is identifiable by a number known as its cas registry number. = = = = molecule = = = = a molecule is the smallest indivisible portion of a pure chemical substance that has its unique set of chemical properties, that is, its potential to undergo a certain set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry ##als force. each of these kinds of bonds is ascribed to some potential. these potentials create the interactions which hold atoms together in molecules or crystals. in many simple compounds, valence bond theory, the valence shell electron pair repulsion model ( vsepr ), and the concept of oxidation number can be used to explain molecular structure and composition. an ionic bond is formed when a metal loses one or more of its electrons, becoming a positively charged cation, and the electrons are then gained by the non - metal atom, becoming a negatively charged anion. the two oppositely charged ions attract one another, and the ionic bond is the electrostatic force of attraction between them. for example, sodium ( na ), a metal, loses one electron to become an na + cation while chlorine ( cl ), a non - metal, gains this electron to become cl−. the ions are held together due to electrostatic attraction, and that compound sodium chloride ( nacl ), or common table salt, is formed. in a covalent bond, one or more pairs of valence electrons are shared by two atoms : the resulting electrically neutral group of bonded atoms is termed a molecule. atoms will share valence electrons in such a way as to create a noble gas electron configuration ( eight electrons in their outermost shell ) for each atom. atoms that tend to combine in such a way that they each have eight electrons in their valence shell are said to follow the octet rule. however, some elements like hydrogen and lithium need only two electrons in their outermost shell to attain this stable configuration ; these atoms are said to follow the duet rule, and in this way they are reaching the electron configuration of the noble gas helium, which has two electrons in its outer shell. similarly, theories from classical physics can be used to predict many ionic structures. with more complicated compounds, such as metal complexes, valence bond theory is less applicable and alternative approaches, such as the molecular orbital theory, are generally used. = = = energy = = = in the context of chemistry, energy is an attribute of a substance as a consequence of its atomic, molecular or aggregate structure. since a chemical transformation is accompanied by a change in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants charges in the nuclei and the negative charges oscillating about them. more than simple attraction and repulsion, the energies and distributions characterize the availability of an electron to bond to another atom. the chemical bond can be a covalent bond, an ionic bond, a hydrogen bond or just because of van der waals force. each of these kinds of bonds is ascribed to some potential. these potentials create the interactions which hold atoms together in molecules or crystals. in many simple compounds, valence bond theory, the valence shell electron pair repulsion model ( vsepr ), and the concept of oxidation number can be used to explain molecular structure and composition. an ionic bond is formed when a metal loses one or more of its electrons, becoming a positively charged cation, and the electrons are then gained by the non - metal atom, becoming a negatively charged anion. the two oppositely charged ions attract one another, and the ionic bond is the electrostatic force of attraction between them. for example, sodium ( na ), a metal, loses one electron to become an na + cation while chlorine ( cl ), a non - metal, gains this electron to become cl−. the ions are held together due to electrostatic attraction, and that compound sodium chloride ( nacl ), or common table salt, is formed. in a covalent bond, one or more pairs of valence electrons are shared by two atoms : the resulting electrically neutral group of bonded atoms is termed a molecule. atoms will share valence electrons in such a way as to create a noble gas electron configuration ( eight electrons in their outermost shell ) for each atom. atoms that tend to combine in such a way that they each have eight electrons in their valence shell are said to follow the octet rule. however, some elements like hydrogen and lithium need only two electrons in their outermost shell to attain this stable configuration ; these atoms are said to follow the duet rule, and in this way they are reaching the electron configuration of the noble gas helium, which has two electrons in its outer shell. similarly, theories from classical physics can be used to predict many ionic structures. with more complicated compounds, such as metal complexes, valence bond theory is less applicable and alternative approaches, such as the molecular orbital theory, are generally used. = = = energy = = = in the context of chemistry, energy is an attribute of a substance as a consequence of its atomic, molecular or aggregate structure. since a chemical transformation is accompanied by a change g. spectroscopy and chromatography. scientists engaged in chemical research are known as chemists. most chemists specialize in one or more sub - disciplines. several concepts are essential for the study of chemistry ; some of them are : = = = matter = = = in chemistry, matter is defined as anything that has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = the atom is the basic unit of chemistry. it consists of a dense core called the atomic nucleus surrounded by a space occupied by an electron cloud. the nucleus is made up of positively charged protons and uncharged neutrons ( together called nucleons ), while the electron cloud consists of negatively charged electrons which orbit the nucleus. in a neutral atom, the negatively charged electrons balance out the positive charge of the protons. the nucleus is dense ; the mass of a nucleon is approximately 1, 836 times that of an electron, yet the radius of an atom is about 10, 000 times that of its nucleus. the atom is also the smallest entity that can be envisaged to retain the chemical properties of the element, such as electronegativity, ionization potential, preferred oxidation state ( s ), coordination number, and preferred types of bonds to form ( e. g., metallic, ionic, covalent ). = = = = element = = = = a chemical element is a pure substance which is composed of a single type of atom, characterized by its particular number of protons in the nuclei of its atoms, known as the atomic number and represented by the symbol z. the mass number is the sum of the number of protons and neutrons in a nucleus. although all the nuclei of all atoms belonging to one element will have the same atomic number, they may not necessarily have the same mass number ; atoms of an element which have different mass numbers are known as isotopes. for example, all atoms with 6 protons in their nuclei are atoms of the chemical element carbon, but atoms of carbon may have mass numbers of 12 or 13. the standard presentation of the chemical elements is in the periodic table, which orders elements by atomic number. the periodic table is arranged in groups, or columns, and periods, or rows. the periodic table is useful in identifying periodic trends Question: What part of an atom is electrically neutral? A) newtons B) protons C) electrons D) neutrons	D) neutrons
Context: lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h pencil. = = = multiple views and projections = = = in most cases, a single view is not sufficient to show all necessary features, and several views are used. types of views include the following : = = = = multiview projection = = = = a multiview projection is a type of orthographic projection that shows the object as it looks from the front, right, left, top, bottom, or back ( e. g. the primary views ), and is typically positioned relative to each other according to the rules of either first - angle or third - angle projection. the origin and vector direction of the projectors ( also called projection lines ) differs, as explained below. in first - angle projection, the parallel projectors originate as if radiated from behind the viewer and pass through the 3d object to project a 2d image onto the orthogonal plane behind it. the 3d object is projected into 2d " paper " space as if you were looking at a radiograph of the object : the top view is under the front view, the right view is at the left of the front view. first - angle projection is the iso standard and is primarily used in europe. in third - angle projection, the parallel projectors originate as if radiated from the far side of the object ##d product that is the focus of a tooling drawing. lines can also be classified by a letter classification in which each line is given a letter. type a lines show the outline of the feature of an object. they are the thickest lines on a drawing and done with a pencil softer than hb. type b lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h pencil. = = = multiple views and projections = = = in most cases, a single view is not sufficient to show all necessary features, and several views are used. types of views include the following : = = = = multiview projection = = = = a multiview projection is a type of orthographic projection that shows the object as it looks from the front, right, left, top, bottom, or back ( e. g. the primary views ), and is typically positioned relative to each other according to the rules of either first - angle or third - angle projection. the origin and vector direction of the projectors ( also called projection lines ) differs, as explained below. in first - angle projection, the parallel projectors originate as if radiated from behind the viewer and pass through the 3d object to project a 2d image onto the orthogonal plane behind it. the 3d object is projected into 2d " paper " space as if you were looking at a polygon is a shape that is bounded by a finite chain of straight line segments closing in a loop to form a closed chain or circuit. these segments are called its edges or sides, and the points where two edges meet are the polygon ' s vertices ( singular : vertex ) or corners. the interior of the polygon is sometimes called its body. an n - gon is a polygon with n sides. a polygon is a 2 - dimensional example of the more general polytope in any number of dimensions. a circle is a simple shape of two - dimensional geometry that is the set of all points in a plane that are at a given distance from a given point, the center. the distance between any of the points and the center is called the radius. it can also be defined as the locus of a point equidistant from a fixed point. a perimeter is a path that surrounds a two - dimensional shape. the term may be used either for the path or its length - it can be thought of as the length of the outline of a shape. the perimeter of a circle or ellipse is called its circumference. area is the quantity that expresses the extent of a two - dimensional figure or shape. there are several well - known formulas for the areas of simple shapes such as triangles, rectangles, and circles. = = = proportions = = = two quantities are proportional if a change in one is always accompanied by a change in the other, and if the changes are always related by use of a constant multiplier. the constant is called the coefficient of proportionality or proportionality constant. if one quantity is always the product of the other and a constant, the two are said to be directly proportional. x and y are directly proportional if the ratio y x { \ displaystyle { \ tfrac { y } { x } } } is constant. if the product of the two quantities is always equal to a constant, the two are said to be inversely proportional. x and y are inversely proportional if the product x y { \ displaystyle xy } is constant. = = = analytic geometry = = = analytic geometry is the study of geometry using a coordinate system. this contrasts with synthetic geometry. usually the cartesian coordinate system is applied to manipulate equations for planes, straight lines, and squares, often in two and sometimes in three dimensions. geometrically, one studies the euclidean plane ( 2 dimensions ) and euclidean space ( 3 dimensions ). as taught in school are commonly referred to as " cross - hatching ". phantom – ( not shown ) are alternately long - and double short - dashed thin lines used to represent a feature or component that is not part of the specified part or assembly. e. g. billet ends that may be used for testing, or the machined product that is the focus of a tooling drawing. lines can also be classified by a letter classification in which each line is given a letter. type a lines show the outline of the feature of an object. they are the thickest lines on a drawing and done with a pencil softer than hb. type b lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h pencil. = = = multiple views and projections = = = in most cases, a single view is not sufficient to show all necessary features, and several views are used. types of views include the following : = = = = multiview projection = = = = a multiview projection is a type of orthographic projection that shows the object as it looks from the front, right, left, top, bottom, or back ( e. g. the primary views ), and is typically positioned relative to each other according to the rules of either first - angle or third - angle projection. the origin and vector direction of the projectors ( are continuous lines used to depict edges directly visible from a particular angle. hidden – are short - dashed lines that may be used to represent edges that are not directly visible. center – are alternately long - and short - dashed lines that may be used to represent the axes of circular features. cutting plane – are thin, medium - dashed lines, or thick alternately long - and double short - dashed that may be used to define sections for section views. section – are thin lines in a pattern ( pattern determined by the material being " cut " or " sectioned " ) used to indicate surfaces in section views resulting from " cutting ". section lines are commonly referred to as " cross - hatching ". phantom – ( not shown ) are alternately long - and double short - dashed thin lines used to represent a feature or component that is not part of the specified part or assembly. e. g. billet ends that may be used for testing, or the machined product that is the focus of a tooling drawing. lines can also be classified by a letter classification in which each line is given a letter. type a lines show the outline of the feature of an object. they are the thickest lines on a drawing and done with a pencil softer than hb. type b lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h - dashed lines, or thick alternately long - and double short - dashed that may be used to define sections for section views. section – are thin lines in a pattern ( pattern determined by the material being " cut " or " sectioned " ) used to indicate surfaces in section views resulting from " cutting ". section lines are commonly referred to as " cross - hatching ". phantom – ( not shown ) are alternately long - and double short - dashed thin lines used to represent a feature or component that is not part of the specified part or assembly. e. g. billet ends that may be used for testing, or the machined product that is the focus of a tooling drawing. lines can also be classified by a letter classification in which each line is given a letter. type a lines show the outline of the feature of an object. they are the thickest lines on a drawing and done with a pencil softer than hb. type b lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h pencil. = = = multiple views and projections = = = in most cases, a single view is not sufficient to show all necessary features, and several views are used. types of views include the following : = = = = multiview projection = = = = a multiview projection is a type of orthographic projection the thickness of freshly made soap films is usually in the micron range, and interference colors make thickness fluctuations easily visible. circular patterns of constant thickness are commonly observed, either a thin film disc in a thicker film or the reverse. in this letter, we evidence the line tension at the origin of these circular patterns. using a well controlled soap film preparation, we produce a piece of thin film surrounded by a thicker film. the thickness profile, measured with a spectral camera, leads to a line tension of the order of 0. 1 nn which drives the relaxation of the thin film shape, initially very elongated, toward a circular shape. a balance between line tension and air friction leads to a quantitative prediction of the relaxation process. such a line tension is expected to play a role in the production of marginal regeneration patches, involved in soap film drainage and stability. , which are not contained in any other space. on the other hand, this excludes surfaces that have singularities, such as the vertex of a conical surface or points where a surface crosses itself. in classical geometry, a surface is generally defined as a locus of a point or a line. for example, a sphere is the locus of a point which is at a given distance of a fixed point, called the center ; a conical surface is the locus of a line passing through a fixed point and crossing a curve ; a surface of revolution is the locus of a curve rotating around a line. a ruled surface is the locus of a moving line satisfying some constraints ; in modern terminology, a ruled surface is a surface, which is a union of lines. = = terminology = = there are several kinds of surfaces that are considered in mathematics. an unambiguous terminology is thus necessary to distinguish them when needed. a topological surface is a surface that is a manifold of dimension two ( see § topological surface ). a differentiable surface is a surfaces that is a differentiable manifold ( see § differentiable surface ). every differentiable surface is a topological surface, but the converse is false. a " surface " is often implicitly supposed to be contained in a euclidean space of dimension 3, typically r3. a surface that is contained in a projective space is called a projective surface ( see § projective surface ). a surface that is not supposed to be included in another space is called an abstract surface. = = examples = = the graph of a continuous function of two variables, defined over a connected open subset of r2 is a topological surface. if the function is differentiable, the graph is a differentiable surface. a plane is both an algebraic surface and a differentiable surface. it is also a ruled surface and a surface of revolution. a circular cylinder ( that is, the locus of a line crossing a circle and parallel to a given direction ) is an algebraic surface and a differentiable surface. a circular cone ( locus of a line crossing a circle, and passing through a fixed point, the apex, which is outside the plane of the circle ) is an algebraic surface which is not a differentiable surface. if one removes the apex, the remainder of the cone is the union of two differentiable surfaces. the surface of a polyhedron is a topological surface, which is neither a differentiable surface nor an algebraic surface. a hyperbolic paraboloid ( the graph of the function z = xy ) is a differentiable surface and there cannot exist a single parametrization that covers the whole surface. therefore, one often considers surfaces which are parametrized by several parametric equations, whose images cover the surface. this is formalized by the concept of manifold : in the context of manifolds, typically in topology and differential geometry, a surface is a manifold of dimension two ; this means that a surface is a topological space such that every point has a neighborhood which is homeomorphic to an open subset of the euclidean plane ( see surface ( topology ) and surface ( differential geometry ) ). this allows defining surfaces in spaces of dimension higher than three, and even abstract surfaces, which are not contained in any other space. on the other hand, this excludes surfaces that have singularities, such as the vertex of a conical surface or points where a surface crosses itself. in classical geometry, a surface is generally defined as a locus of a point or a line. for example, a sphere is the locus of a point which is at a given distance of a fixed point, called the center ; a conical surface is the locus of a line passing through a fixed point and crossing a curve ; a surface of revolution is the locus of a curve rotating around a line. a ruled surface is the locus of a moving line satisfying some constraints ; in modern terminology, a ruled surface is a surface, which is a union of lines. = = terminology = = there are several kinds of surfaces that are considered in mathematics. an unambiguous terminology is thus necessary to distinguish them when needed. a topological surface is a surface that is a manifold of dimension two ( see § topological surface ). a differentiable surface is a surfaces that is a differentiable manifold ( see § differentiable surface ). every differentiable surface is a topological surface, but the converse is false. a " surface " is often implicitly supposed to be contained in a euclidean space of dimension 3, typically r3. a surface that is contained in a projective space is called a projective surface ( see § projective surface ). a surface that is not supposed to be included in another space is called an abstract surface. = = examples = = the graph of a continuous function of two variables, defined over a connected open subset of r2 is a topological surface. if the function is differentiable, the graph is a differentiable surface. a plane is both an algebraic surface and a differentiable surface. it is also a ruled surface and a surface of revolution. a circular cylinder ( that is, the locus of a line crossing a horn angle between a circle and its tangent is considered in euclid ' s elements, and euclid remarks that it is smaller than any acute rectilinear angle. already in antiquity, proclus wondered whether it is possible to bisect horn angles. we will give a construction of a bisector which was within the means of ancient geometers since the time of archimedes and apollonius. we will also compare it to the conformal bisection method introduced in modern times. Question: Bar, circle, and line are all types of what? A) theories B) graphs C) maps D) algorithms	B) graphs
Context: to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, found mainly in prokaryotes and some lower eukaryotes ( e. g., caenorhabditis elegans ). in positive regulation of gene expression, the activator is the transcription factor that stimulates transcription when it binds to the sequence near or at the promoter. negative regulation occurs when another transcription factor called a repressor binds to a dna sequence called an operator, which is part of an operon, to prevent transcription. repressors can be inhibited by compounds called inducers ( e. g., allolactose ), thereby allowing transcription to occur. specific genes that can be activated by inducers are called inducible genes, in contrast to constitutive genes that are almost constantly active. in contrast to both, structural genes encode proteins that are not involved in gene regulation. in addition to regulatory events involving the promoter, gene expression can also be regulated by epigenetic changes to chromatin, which is a complex of dna and protein found in eukaryotic cells. = = = genes, development, and evolution = = = development is the process by which a multicellular organism ( plant or animal ) goes through a series of changes, starting from a single cell, and taking on various forms that are characteristic of its life cycle. there are four key processes that underlie development : determination, differentiation, morphogenesis, and growth. determination sets the developmental fate of a cell, which becomes more restrictive during development. differentiation is the process by which specialized cells arise from less specialized cells such as stem cells. stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. cellular differentiation dramatically changes a cell ' s size, shape, membrane potential, metabolic activity, and responsiveness to signals, which are largely due to chromatin, which is a complex of dna and protein found in eukaryotic cells. = = = genes, development, and evolution = = = development is the process by which a multicellular organism ( plant or animal ) goes through a series of changes, starting from a single cell, and taking on various forms that are characteristic of its life cycle. there are four key processes that underlie development : determination, differentiation, morphogenesis, and growth. determination sets the developmental fate of a cell, which becomes more restrictive during development. differentiation is the process by which specialized cells arise from less specialized cells such as stem cells. stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. cellular differentiation dramatically changes a cell ' s size, shape, membrane potential, metabolic activity, and responsiveness to signals, which are largely due to highly controlled modifications in gene expression and epigenetics. with a few exceptions, cellular differentiation almost never involves a change in the dna sequence itself. thus, different cells can have very different physical characteristics despite having the same genome. morphogenesis, or the development of body form, is the result of spatial differences in gene expression. a small fraction of the genes in an organism ' s genome called the developmental - genetic toolkit control the development of that organism. these toolkit genes are highly conserved among phyla, meaning that they are ancient and very similar in widely separated groups of animals. differences in deployment of toolkit genes affect the body plan and the number, identity, and pattern of body parts. among the most important toolkit genes are the hox genes. hox genes determine where repeating parts, such as the many vertebrae of snakes, will grow in a developing embryo or larva. = = evolution = = = = = evolutionary processes = = = evolution is a central organizing concept in biology. it is the change in heritable characteristics of populations over successive generations. in artificial selection, animals were selectively bred for specific traits. given that traits are inherited, populations contain a varied mix of traits, and reproduction is able to increase any population, darwin argued that in the natural world, it was nature that played the role of humans in selecting for specific traits. darwin inferred that individuals who possessed heritable traits better adapted to their environments are more likely to survive and produce more offspring than other individuals. he further inferred that this would lead to the cross. the chromosome theory of inheritance, which states that genes are found on chromosomes, was supported by thomas morgans ' s experiments with fruit flies, which established the sex linkage between eye color and sex in these insects. = = = genes and dna = = = a gene is a unit of heredity that corresponds to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing to a region of deoxyribonucleic acid ( dna ) that carries genetic information that controls form or function of an organism. dna is composed of two polynucleotide chains that coil around each other to form a double helix. it is found as linear chromosomes in eukaryotes, and circular chromosomes in prokaryotes. the set of chromosomes in a cell is collectively known as its genome. in eukaryotes, dna is mainly in the cell nucleus. in prokaryotes, the dna is held within the nucleoid. the genetic information is held within genes, and the complete assemblage in an organism is called its genotype. dna replication is a semiconservative process whereby each strand serves as a template for a new strand of dna. mutations are heritable changes in dna. they can arise spontaneously as a result of replication errors that were not corrected by proofreading or can be induced by an environmental mutagen such as a chemical ( e. g., nitrous acid, benzopyrene ) or radiation ( e. g., x - ray, gamma ray, ultraviolet radiation, particles emitted by unstable isotopes ). mutations can lead to phenotypic effects such as loss - of - function, gain - of - function, and conditional mutations. some mutations are beneficial, as they are a source of genetic variation for evolution. others are harmful if they were to result in a loss of function of genes needed for survival. = = = gene expression = = = gene expression is the molecular process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, invertebrates, or protozoans, the protist grouping is not a formal taxonomic group but is used for convenience. most protists are unicellular ; these are called microbial eukaryotes. plants are mainly multicellular organisms, predominantly photosynthetic eukaryotes of the kingdom plantae, which would exclude fungi and some algae. plant cells were derived by endosymbiosis of a cyanobacterium into an early eukaryote about one billion years ago, which gave rise to chloroplasts. the first several clades that emerged following primary endosymbiosis were aquatic and most of the aquatic photosynthetic eukaryotic organisms are collectively described as algae, which is a term of convenience as not all algae are closely related. algae comprise several distinct clades such as glaucophytes, which are microscopic freshwater algae that may have resembled in form to the early unicellular ancestor of plantae. unlike glaucophytes, the other algal clades such as red and green algae are multicellular. green algae comprise three major clades : chlorophytes, coleochaetophytes, and stoneworts. fungi are eukaryotes that digest foods outside their bodies, secreting digestive enzymes that break down large food molecules before absorbing them through their cell membranes. many fungi are also saprobes, feeding on dead organic matter, making them important decomposers in ecological systems. animals are multicellular eukaryotes. with few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, . most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell, there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support and the creation of genetically modified crops. = = = epigenetics = = = epigenetics is the study of heritable changes in gene function that cannot be explained by changes in the underlying dna sequence but cause the organism ' s genes to behave ( or " express themselves " ) differently. one example of epigenetic change is the marking of the genes by dna methylation which determines whether they will be expressed or not. gene expression can also be controlled by repressor proteins that attach to silencer regions of the dna and prevent that region of the dna code from being expressed. epigenetic marks may be added or removed from the dna during programmed stages of development of the plant, and are responsible, for example, for the differences between anthers, petals and normal leaves, despite the fact that they all have the same underlying genetic code. epigenetic changes may be temporary or may remain through successive cell divisions for the remainder of the cell ' s life. some epigenetic changes have been shown to be heritable, while others are reset in the germ cells. epigenetic changes in eukaryotic biology serve to regulate the process of cellular differentiation. during morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo, which in turn become fully differentiated cells. a single fertilised egg cell, the zygote, gives rise to the many different plant cell types including parenchyma, xylem vessel elements, phloem sieve tubes, guard cells of the epidermis, etc. as it continues to divide. the process results from the epigenetic activation of some genes and inhibition of others. unlike animals, many plant cells, particularly those of the parenchyma, do not terminally differentiate, remaining totipotent with the ability to give rise to a new individual plant. exceptions include highly lignified cells, the sclerenchyma and xylem which are dead at maturity, and the phloem sieve tubes which lack nuclei. while plants use many of the same epigenetic mechanisms as animals, such as chromatin remodelling, an alternative hypothesis is that plants set their gene expression patterns using positional information from the environment and surrounding cells to determine their developmental fate. epigenetic changes can lead to paramutations, which do not follow the mendelian heritage rules. these epigenetic marks are carried from one generation to the next, process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, found mainly in prokaryotes and some lower eukaryotes ( e. g., caenorhabditis elegans ). in positive regulation of gene expression, the activator is the transcription factor that stimulates transcription when it binds to the sequence near or at the promoter. negative regulation occurs when another transcription factor called a repressor binds to a dna sequence called an operator, which is part of an operon, to prevent transcription. repressors can be inhibited by compounds called inducers ( e. g., allolactose ), thereby allowing transcription to occur. specific genes that can be activated by inducers are called inducible genes, in contrast to constitutive genes that are almost constantly active. in contrast to both, structural genes encode proteins that are not involved in gene regulation. in addition to regulatory events involving the promoter, gene expression can also be regulated by epigenetic changes to chromatin, which is a complex of dna and protein found in eukaryotic cells. = = = genes, development, and evolution = = = development is the process by which a multicellular organism ( plant or animal ) goes through a series of changes, starting from a single cell, and taking on various forms that are characteristic of its life cycle. there are four key processes that underlie development : determination, differentiation, morphogenesis, and growth. determination sets the developmental fate of a cell, which becomes more restrictive during development. differentiation is the process by which specialized cells arise from less specialized cells such as stem occurs when another transcription factor called a repressor binds to a dna sequence called an operator, which is part of an operon, to prevent transcription. repressors can be inhibited by compounds called inducers ( e. g., allolactose ), thereby allowing transcription to occur. specific genes that can be activated by inducers are called inducible genes, in contrast to constitutive genes that are almost constantly active. in contrast to both, structural genes encode proteins that are not involved in gene regulation. in addition to regulatory events involving the promoter, gene expression can also be regulated by epigenetic changes to chromatin, which is a complex of dna and protein found in eukaryotic cells. = = = genes, development, and evolution = = = development is the process by which a multicellular organism ( plant or animal ) goes through a series of changes, starting from a single cell, and taking on various forms that are characteristic of its life cycle. there are four key processes that underlie development : determination, differentiation, morphogenesis, and growth. determination sets the developmental fate of a cell, which becomes more restrictive during development. differentiation is the process by which specialized cells arise from less specialized cells such as stem cells. stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. cellular differentiation dramatically changes a cell ' s size, shape, membrane potential, metabolic activity, and responsiveness to signals, which are largely due to highly controlled modifications in gene expression and epigenetics. with a few exceptions, cellular differentiation almost never involves a change in the dna sequence itself. thus, different cells can have very different physical characteristics despite having the same genome. morphogenesis, or the development of body form, is the result of spatial differences in gene expression. a small fraction of the genes in an organism ' s genome called the developmental - genetic toolkit control the development of that organism. these toolkit genes are highly conserved among phyla, meaning that they are ancient and very similar in widely separated groups of animals. differences in deployment of toolkit genes affect the body plan and the number, identity, and pattern of body parts. among the most important toolkit genes are the hox genes. hox genes determine where repeating parts, such as the many vertebrae of snakes, will grow in a developing embryo or larva. = = evolution = = = = = evolutionary symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mitochondria and chloroplasts, both of which are now part of modern - day eukaryotic cells. the major lineages of eukaryotes diversified in the precambrian about 1. 5 billion years ago and can be classified into eight major clades : alveolates, excavates, stramenopiles, plants, rhizarians, amoebozoans, fungi, and animals. five of these clades are collectively known as protists, which are mostly microscopic eukaryotic organisms that are not plants, fungi, or animals. while it is likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, invertebrates, or protozoans, the protist grouping is not a formal taxonomic group but is used for convenience. most protists are unicellular ; these are called microbial eukaryotes. plants are mainly multicellular organisms, predominantly photosynthetic eukaryotes of the kingdom plantae, which would exclude fungi and some algae. plant cells were derived by endosymbiosis of a cyanobacterium into an early eukaryote about one billion years ago, which gave rise to chloroplasts. the first several clades that emerged following primary endosymbiosis were aquatic and most of the aquatic photosynthetic eukaryotic organisms are collectively described as algae, which is a term of convenience as not all algae are closely related. algae comprise several distinct clades such as glaucophytes, which are microscopic freshwater algae that may have resembled in form to the early unicellular ancestor of plantae. unlike glaucophytes, the other algal clades such as red and green algae are multicellular. green algae comprise three major clades : chlorophytes, coleochaetophytes, and stoneworts. fungi are eukaryotes that Question: Unlike eukaryotic cells, dna and rna synthesis in prokaryotic cells occurs together with synthesis of what? A) mutation B) fruit C) membrane D) protein	D) protein
Context: ##yotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial fertile and resistant, towards biotic and abiotic stress, plants and ensures application of environmentally friendly fertilizers and the use of biopesticides, it is mainly focused on the development of agriculture. on the other hand, some of the uses of green biotechnology involve microorganisms to clean and reduce waste. red biotechnology is the use of biotechnology in the medical and pharmaceutical industries, and health preservation. this branch involves the production of vaccines and antibiotics, regenerative therapies, creation of artificial organs and new diagnostics of diseases. as well as the development of hormones, stem cells, antibodies, sirna and diagnostic tests. white biotechnology, also known as industrial biotechnology, is biotechnology applied to industrial processes. an example is the designing of an organism to produce a useful chemical. another example is the using of enzymes as industrial catalysts to either produce valuable chemicals or destroy hazardous / polluting chemicals. white biotechnology tends to consume less in resources than traditional processes used to produce industrial goods. yellow biotechnology refers to the use of biotechnology in food production ( food industry ), for example in making wine ( winemaking ), cheese ( cheesemaking ), and beer ( brewing ) by fermentation. it has also been used to refer to biotechnology applied to insects. this includes biotechnology - based approaches for the control of harmful insects, the characterisation and utilisation of active ingredients or genes of insects for research, or application in agriculture and medicine and various other approaches. gray biotechnology is dedicated to environmental applications, and focused on the maintenance of biodiversity and the remotion of pollutants. brown biotechnology is related to the management of arid lands and deserts. one application is the creation of enhanced seeds that resist extreme environmental conditions of arid regions, which is related to the innovation, creation of agriculture techniques and management of resources. violet biotechnology is related to law, ethical and philosophical issues around biotechnology. microbial biotechnology has been proposed for the rapidly emerging area of biotechnology applications in space and microgravity ( space bioeconomy ) dark biotechnology is the color associated with bioterrorism or biological weapons and biowarfare which uses microorganisms, and toxins to cause diseases and death in humans, livestock and crops. = = = medicine = = = in medicine, modern biotechnology has many applications in areas such as pharmaceutical drug discoveries and production, pharmacogenomics, and genetic testing ( or genetic screening ). in 2021, nearly 40 % of the total company value of pharmaceutical biotech companies worldwide were active in oncology applications continue to expand as researchers develop new kinds of ceramics to serve different purposes. zirconium dioxide ceramics are used in the manufacture of knives. the blade of the ceramic knife will stay sharp for much longer than that of a steel knife, although it is more brittle and can be snapped by dropping it on a hard surface. ceramics such as alumina, boron carbide and silicon carbide have been used in bulletproof vests to repel small arms rifle fire. such plates are known commonly as ballistic plates. similar material is used to protect cockpits of some military aircraft, because of the low weight of the material. silicon nitride parts are used in ceramic ball bearings. their higher hardness means that they are much less susceptible to wear and can offer more than triple lifetimes. they also deform less under load meaning they have less contact with the bearing retainer walls and can roll faster. in very high speed applications, heat from friction during rolling can cause problems for metal bearings ; problems which are reduced by the use of ceramics. ceramics are also more chemically resistant and can be used in wet environments where steel bearings would rust. the major drawback to using ceramics is a significantly higher cost. in many cases their electrically insulating properties may also be valuable in bearings. in the early 1980s, toyota researched production of an adiabatic ceramic engine which can run at a temperature of over 6000 °f ( 3300 °c ). ceramic engines do not require a cooling system and hence allow a major weight reduction and therefore greater fuel efficiency. fuel efficiency of the engine is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such surface. ceramics such as alumina, boron carbide and silicon carbide have been used in bulletproof vests to repel small arms rifle fire. such plates are known commonly as ballistic plates. similar material is used to protect cockpits of some military aircraft, because of the low weight of the material. silicon nitride parts are used in ceramic ball bearings. their higher hardness means that they are much less susceptible to wear and can offer more than triple lifetimes. they also deform less under load meaning they have less contact with the bearing retainer walls and can roll faster. in very high speed applications, heat from friction during rolling can cause problems for metal bearings ; problems which are reduced by the use of ceramics. ceramics are also more chemically resistant and can be used in wet environments where steel bearings would rust. the major drawback to using ceramics is a significantly higher cost. in many cases their electrically insulating properties may also be valuable in bearings. in the early 1980s, toyota researched production of an adiabatic ceramic engine which can run at a temperature of over 6000 °f ( 3300 °c ). ceramic engines do not require a cooling system and hence allow a major weight reduction and therefore greater fuel efficiency. fuel efficiency of the engine is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive industrial applications. this branch of biotechnology is the most used for the industries of refining and combustion principally on the production of bio - oils with photosynthetic micro - algae. green biotechnology is biotechnology applied to agricultural processes. an example would be the selection and domestication of plants via micropropagation. another example is the designing of transgenic plants to grow under specific environments in the presence ( or absence ) of chemicals. one hope is that green biotechnology might produce more environmentally friendly solutions than traditional industrial agriculture. an example of this is the engineering of a plant to express a pesticide, thereby ending the need of external application of pesticides. an example of this would be bt corn. whether or not green biotechnology products such as this are ultimately more environmentally friendly is a topic of considerable debate. it is commonly considered as the next phase of green revolution, which can be seen as a platform to eradicate world hunger by using technologies which enable the production of more fertile and resistant, towards biotic and abiotic stress, plants and ensures application of environmentally friendly fertilizers and the use of biopesticides, it is mainly focused on the development of agriculture. on the other hand, some of the uses of green biotechnology involve microorganisms to clean and reduce waste. red biotechnology is the use of biotechnology in the medical and pharmaceutical industries, and health preservation. this branch involves the production of vaccines and antibiotics, regenerative therapies, creation of artificial organs and new diagnostics of diseases. as well as the development of hormones, stem cells, antibodies, sirna and diagnostic tests. white biotechnology, also known as industrial biotechnology, is biotechnology applied to industrial processes. an example is the designing of an organism to produce a useful chemical. another example is the using of enzymes as industrial catalysts to either produce valuable chemicals or destroy hazardous / polluting chemicals. white biotechnology tends to consume less in resources than traditional processes used to produce industrial goods. yellow biotechnology refers to the use of biotechnology in food production ( food industry ), for example in making wine ( winemaking ), cheese ( cheesemaking ), and beer ( brewing ) by fermentation. it has also been used to refer to biotechnology applied to insects. this includes biotechnology - based approaches for the control of harmful insects, the characterisation and utilisation of active ingredients or genes of insects for research, or application in agriculture and medicine and various other approaches. gray biotechnology is dedicated to environmental applications, and focused on the maintenance of biodiversity and the remotion of poll excavates, stramenopiles, plants, rhizarians, amoebozoans, fungi, and animals. five of these clades are collectively known as protists, which are mostly microscopic eukaryotic organisms that are not plants, fungi, or animals. while it is likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, invertebrates, or protozoans, the protist grouping is not a formal taxonomic group but is used for convenience. most protists are unicellular ; these are called microbial eukaryotes. plants are mainly multicellular organisms, predominantly photosynthetic eukaryotes of the kingdom plantae, which would exclude fungi and some algae. plant cells were derived by endosymbiosis of a cyanobacterium into an early eukaryote about one billion years ago, which gave rise to chloroplasts. the first several clades that emerged following primary endosymbiosis were aquatic and most of the aquatic photosynthetic eukaryotic organisms are collectively described as algae, which is a term of convenience as not all algae are closely related. algae comprise several distinct clades such as glaucophytes, which are microscopic freshwater algae that may have resembled in form to the early unicellular ancestor of plantae. unlike glaucophytes, the other algal clades such as red and green algae are multicellular. green algae comprise three major clades : chlorophytes, coleochaetophytes, and stoneworts. fungi are eukaryotes that digest foods outside their bodies, secreting digestive enzymes that break down large food molecules before absorbing them through their cell membranes. many fungi are also saprobes, feeding on dead organic matter, making them important decomposers in ecological systems. animals are multicellular eukaryotes. with few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mit for natural scientists, with the creation of transgenic organisms one of the most important tools for analysis of gene function. genes and other genetic information from a wide range of organisms can be inserted into bacteria for storage and modification, creating genetically modified bacteria in the process. bacteria are cheap, easy to grow, clonal, multiply quickly, relatively easy to transform and can be stored at - 80 °c almost indefinitely. once a gene is isolated it can be stored inside the bacteria providing an unlimited supply for research. organisms are genetically engineered to discover the functions of certain genes. this could be the effect on the phenotype of the organism, where the gene is expressed or what other genes it interacts with. these experiments generally involve loss of function, gain of function, tracking and expression. loss of function experiments, such as in a gene knockout experiment, in which an organism is engineered to lack the activity of one or more genes. in a simple knockout a copy of the desired gene has been altered to make it non - functional. embryonic stem cells incorporate the altered gene, which replaces the already present functional copy. these stem cells are injected into blastocysts, which are implanted into surrogate mothers. this allows the experimenter to analyse the defects caused by this mutation and thereby determine the role of particular genes. it is used especially frequently in developmental biology. when this is done by creating a library of genes with point mutations at every position in the area of interest, or even every position in the whole gene, this is called " scanning mutagenesis ". the simplest method, and the first to be used, is " alanine scanning ", where every position in turn is mutated to the unreactive amino acid alanine. gain of function experiments, the logical counterpart of knockouts. these are sometimes performed in conjunction with knockout experiments to more finely establish the function of the desired gene. the process is much the same as that in knockout engineering, except that the construct is designed to increase the function of the gene, usually by providing extra copies of the gene or inducing synthesis of the protein more frequently. gain of function is used to tell whether or not a protein is sufficient for a function, but does not always mean it is required, especially when dealing with genetic or functional redundancy. tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. one way to do this is to replace the wild - type gene with a ' fusion ' gene, which is a juxtaposition Question: What type of bacteria are sometimes used as weapons of bioterrorism? A) hypothermic B) pathogenic C) carcinogenic D) avian	B) pathogenic
Context: joints. = = = metal alloys = = = the alloys of iron ( steel, stainless steel, cast iron, tool steel, alloy steels ) make up the largest proportion of metals today both by quantity and commercial value. iron alloyed with various proportions of carbon gives low, mid and high carbon steels. an iron - carbon alloy is only considered steel if the carbon level is between 0. 01 % and 2. 00 % by weight. for steels, the hardness and tensile strength of the steel is related to the amount of carbon present, with increasing carbon levels also leading to lower ductility and toughness. heat treatment processes such as quenching and tempering can significantly change these properties, however. in contrast, certain metal alloys exhibit unique properties where their size and density remain unchanged across a range of temperatures. cast iron is defined as an iron – carbon alloy with more than 2. 00 %, but less than 6. 67 % carbon. stainless steel is defined as a regular steel alloy with greater than 10 % by weight alloying content of chromium. nickel and molybdenum are typically also added in stainless steels. other significant metallic alloys are those of aluminium, titanium, copper and magnesium. copper alloys have been known for a long time ( since the bronze age ), while the alloys of the other three metals have been relatively recently developed. due to the chemical reactivity of these metals, the electrolytic extraction processes required were only developed relatively recently. the alloys of aluminium, titanium and magnesium are also known and valued for their high strength to weight ratios and, in the case of magnesium, their ability to provide electromagnetic shielding. these materials are ideal for situations where high strength to weight ratios are more important than bulk cost, such as in the aerospace industry and certain automotive engineering applications. = = = semiconductors = = = a semiconductor is a material that has a resistivity between a conductor and insulator. modern day electronics run on semiconductors, and the industry had an estimated us $ 530 billion market in 2021. its electronic properties can be greatly altered through intentionally introducing impurities in a process referred to as doping. semiconductor materials are used to build diodes, transistors, light - emitting diodes ( leds ), and analog and digital electric circuits, among their many uses. semiconductor devices have replaced thermionic devices like vacuum tubes in most applications. semiconductor devices are manufactured both as single discrete devices and as integrated circuits ( ics ), which consist of a number — from a was done using the spinning wheel and weaving was done on a hand - and - foot - operated loom. it took from three to five spinners to supply one weaver. the invention of the flying shuttle in 1733 doubled the output of a weaver, creating a shortage of spinners. the spinning frame for wool was invented in 1738. the spinning jenny, invented in 1764, was a machine that used multiple spinning wheels ; however, it produced low quality thread. the water frame patented by richard arkwright in 1767, produced a better quality thread than the spinning jenny. the spinning mule, patented in 1779 by samuel crompton, produced a high quality thread. the power loom was invented by edmund cartwright in 1787. in the mid - 1750s, the steam engine was applied to the water power - constrained iron, copper and lead industries for powering blast bellows. these industries were located near the mines, some of which were using steam engines for mine pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, the classical and the quantum motion of a massive body in the rotating tube is considered. photon is included. the spin motion described by the bargmann - michel - telegdi equation is considered in the rotation tube and rotating system. inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase which constitutes anywhere from 30 % [ m / m ] to 90 % [ m / m ] of its composition by volume, yielding an array of materials with interesting thermomechanical properties. in the processing of glass - ceramics, molten glass is cooled down gradually before reheating and annealing. in this heat in 1738. the spinning jenny, invented in 1764, was a machine that used multiple spinning wheels ; however, it produced low quality thread. the water frame patented by richard arkwright in 1767, produced a better quality thread than the spinning jenny. the spinning mule, patented in 1779 by samuel crompton, produced a high quality thread. the power loom was invented by edmund cartwright in 1787. in the mid - 1750s, the steam engine was applied to the water power - constrained iron, copper and lead industries for powering blast bellows. these industries were located near the mines, some of which were using steam engines for mine pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened in 1830, the rocket locomotive of robert stephenson being one of its first working locomotives used. manufacture of ships ' pulley blocks by all - metal machines at the portsmouth block mills in 1803 instigated the age of sustained mass production. machine tools used by engineers to manufacture parts began in the first decade of the century, notably by richard roberts and joseph whitworth. the development of interchangeable parts through what is now called the american system of manufacturing began in the firearms industry at the u. s. federal arsenals in the early 19th century, and became widely used by the end of the century. until the enlightenment era, little progress as a traditional tool of external assistance, crutches play an important role in society. they have a wide range of applications to help either the elderly and disabled to walk or to treat certain illnesses or for post - operative rehabilitation. but there are many different types of crutches, including shoulder crutches and elbow crutches. how to choose has become an issue that deserves to be debated. because while crutches help people walk, they also have an impact on the body. inappropriate choice of crutches or long - term misuse can lead to problems such as scoliosis. previous studies were mainly experimental measurements or the construction of dynamic models to calculate the load on joints with crutches. these studies focus only on the level of the joints, ignoring the role that muscles play in this process. although some also take into account the degree of muscle activation, there is still a lack of quantitative analysis. the traditional dynamic model can be used to calculate the load on each joint. however, due to the activation of the muscle, this situation only causes part of the load transmitted to the joint, and the work of the chair will compensate the other part of the load. analysis at the muscle level allows a better understanding of the impact of crutches on the body. by comparing the levels of activation of the trunk muscles, it was found that the use of crutches for walking, especially a single crutch, can cause a large difference in the activation of the back muscles on the left and right sides, and this difference will cause muscle degeneration for a long time, leading to scoliosis. in this article taking scoliosis as an example, by analyzing the muscles around the spine, we can better understand the pathology and can better prevent diseases. the objective of this article is to analyze normal walking compared to walking with one or two crutches using opensim software to obtain the degree of activation of different muscles in order to analyze the impact of crutches on the body. . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = driven by cheap energy in the form of coal, produced in ever - increasing amounts from the abundant resources of britain. the british industrial revolution is characterized by developments in the areas of textile machinery, mining, metallurgy, transport and the invention of machine tools. before invention of machinery to spin yarn and weave cloth, spinning was done using the spinning wheel and weaving was done on a hand - and - foot - operated loom. it took from three to five spinners to supply one weaver. the invention of the flying shuttle in 1733 doubled the output of a weaver, creating a shortage of spinners. the spinning frame for wool was invented in 1738. the spinning jenny, invented in 1764, was a machine that used multiple spinning wheels ; however, it produced low quality thread. the water frame patented by richard arkwright in 1767, produced a better quality thread than the spinning jenny. the spinning mule, patented in 1779 by samuel crompton, produced a high quality thread. the power loom was invented by edmund cartwright in 1787. in the mid - 1750s, the steam engine was applied to the water power - constrained iron, copper and lead industries for powering blast bellows. these industries were located near the mines, some of which were using steam engines for mine pumping. steam engines were too powerful for leather bellows, so cast iron blowing cylinders were developed in 1768. steam powered blast furnaces achieved higher temperatures, allowing the use of more lime in iron blast furnace feed. ( lime rich slag was not free - flowing at the previously used temperatures. ) with a sufficient lime ratio, sulfur from coal or coke fuel reacts with the slag so that the sulfur does not contaminate the iron. coal and coke were cheaper and more abundant fuel. as a result, iron production rose significantly during the last decades of the 18th century. coal converted to coke fueled higher temperature blast furnaces and produced cast iron in much larger amounts than before, allowing the creation of a range of structures such as the iron bridge. cheap coal meant that industry was no longer constrained by water resources driving the mills, although it continued as a valuable source of power. the steam engine helped drain the mines, so more coal reserves could be accessed, and the output of coal increased. the development of the high - pressure steam engine made locomotives possible, and a transport revolution followed. the steam engine which had existed since the early 18th century, was practically applied to both steamboat and railway transportation. the liverpool and manchester railway, the first purpose - built railway line, opened firstly, we shall introduce the so - called snapping out walsh ' s brownian motion and present its relation with walsh ' s brownian motion. then the stiff problem related to walsh ' s brownian motion will be described and we shall build a phase transition for it. the snapping out walsh ' s brownian motion corresponds to the so - called semi - permeable pattern of this stiff problem. 28 size spectra of extensive air showers from 7 different experiments are analysed consistently. they are fitted by adjusting either 4 or 5 parameters : knee position, power law exponents above and below the knee, overall intensity and, in addition, a parameter describing the smoothness of the bend. the residuals are then normalized to the same knee position and averaged. when 5 parameters are employed no systematic deviation from a single smooth knee is apparent at the 1 % level up to a factor of 4 above the knee. at larger shower sizes a moderately significant deviation can be seen whose shape and position are compatible with a second knee caused by iron group nuclei. Question: What is the name of a joint in which one bone rotates in relation to another bone? A) pivot joint B) gliding C) ball and socket D) hinge	A) pivot joint
Context: two local macros are included ( gothic. sty and fleqn. sty ) written for the book " mathematicians from saint petersburg and their theorems ". electromagnetic induction. the transmission speed ranges from 2 mbit / s to 10 gbit / s. twisted pair cabling comes in two forms : unshielded twisted pair ( utp ) and shielded twisted - pair ( stp ). each form comes in several category ratings, designed for use in various scenarios. an optical fiber is a glass fiber. it carries pulses of light that represent data via lasers and optical amplifiers. some advantages of optical fibers over metal wires are very low transmission loss and immunity to electrical interference. using dense wave division multiplexing, optical fibers can simultaneously carry multiple streams of data on different wavelengths of light, which greatly increases the rate that data can be sent to up to trillions of bits per second. optic fibers can be used for long runs of cable carrying very high data rates, and are used for undersea communications cables to interconnect continents. there are two basic types of fiber optics, single - mode optical fiber ( smf ) and multi - mode optical fiber ( mmf ). single - mode fiber has the advantage of being able to sustain a coherent signal for dozens or even a hundred kilometers. multimode fiber is cheaper to terminate but is limited to a few hundred or even only a few dozens of meters, depending on the data rate and cable grade. = = = wireless = = = network connections can be established wirelessly using radio or other electromagnetic means of communication. terrestrial microwave – terrestrial microwave communication uses earth - based transmitters and receivers resembling satellite dishes. terrestrial microwaves are in the low gigahertz range, which limits all communications to line - of - sight. relay stations are spaced approximately 40 miles ( 64 km ) apart. communications satellites – satellites also communicate via microwave. the satellites are stationed in space, typically in geosynchronous orbit 35, 400 km ( 22, 000 mi ) above the equator. these earth - orbiting systems are capable of receiving and relaying voice, data, and tv signals. cellular networks use several radio communications technologies. the systems divide the region covered into multiple geographic areas. each area is served by a low - power transceiver. radio and spread spectrum technologies – wireless lans use a high - frequency radio technology similar to digital cellular. wireless lans use spread spectrum technology to enable communication between multiple devices in a limited area. ieee 802. 11 defines a common flavor of open - standards wireless radio - wave technology known as wi - fi. free - space optical communication uses visible or invisible light for communications. in most cases, line - of using the same method we provide negative answers to the following questions : is it possible to find real equations for complex polynomials in two variables up to topological equivalence ( lee rudolph )? can two topologically equivalent polynomials be connected by a continuous family of topologically equivalent polynomials? in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in cytokinesis. this can occur early in development to produce an autopolyploid or partly autopolyploid organism, or during normal processes of cellular differentiation to produce some cell types that are polyploid ( endopolyploidy ), or during gamete formation. an allopolyploid plant may result from a hybridisation event between two different species. both autopolyploid and allopolyploid plants can often reproduce normally, but may be unable to cross - breed successfully with the parent population because there is a mismatch in chromosome numbers. these plants that are reproductively isolated from the parent species but live within the same geographical area, may be sufficiently successful to form a new species. some otherwise sterile plant polyploids can still reproduce vegetatively or by seed apomixis, forming clonal populations of identical individuals. durum wheat is a fertile tetraploid allopolyploid hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable of creating cells of the other and producing adventitious shoots or roots. stolons and tubers are examples of shoots that can grow roots. roots that spread out close to the surface, such as those of willows, can produce shoots and ultimately new plants. in the event that one of the systems is lost, the other can often regrow it. in fact it is possible to grow an entire plant from a single leaf, as is the case with plants in streptocarpus sect. saintpaulia, or even a single cell – which can dedifferentiate into a callus ( a mass of unspecialised cells ) that can grow into a new plant. in vascular plants, the xylem and phloem are the conductive tissues that transport resources between shoots and roots. roots are often adapted to store food such as sugars or starch, as in sugar beets and carrots. i briefly review the progress of accretion disc theory since the seminal paper of shakura and sunyaev. ##nita and hamangia, which are often grouped together under the name of ' old europe '. with the carpatho - balkan region described as the ' earliest metallurgical province in eurasia ', its scale and technical quality of metal production in the 6th – 5th millennia bc totally overshadowed that of any other contemporary production centre. the earliest documented use of lead ( possibly native or smelted ) in the near east dates from the 6th millennium bc, is from the late neolithic settlements of yarim tepe and arpachiyah in iraq. the artifacts suggest that lead smelting may have predated copper smelting. metallurgy of lead has also been found in the balkans during the same period. copper smelting is documented at sites in anatolia and at the site of tal - i iblis in southeastern iran from c. 5000 bc. copper smelting is first documented in the delta region of northern egypt in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and . n. c. e. in total. unlike with later incubus albums, the songs were recorded to tape, and the band wanted to avoid creating music that they wouldn ' t be able to perform live. during the recording, the band utilized older analogue gear that they described as having " phat sounds and spider webs. " incubus chose jim wirt to produce the album, since he had worked with them on earlier recordings. einziger believed that wirt helped encourage their creativity during the recording of s. c. i. e. n. c. e., saying in 1997, " he helps us come up with strange stuff and he likes it when we do. he doesn ' t try to change what we do, he tries to enhance it. " einziger added in the same interview, " when we signed our record deal and started working on this album, we were worried that someone would come along and tell us to hold back, and try and make our songs a little more palatable. but that never happened. they kinda just said, ' do whatever you want '. with that kind of support, we just let everything kind of run wild. " pasillas similarly noted the lack of outside influence in 2017, saying " we didn ’ t have label people coming in hovering above us making sure we weren ' t wasting money. we were left to our own devices and we worked well that way. " in a 2018 interview with australian magazine heavy, boyd remembered " when we wrote s. c. i. e. n. c. e. we didn ' t know about any songwriting rules. it was like a chopped salad, schizophrenic album put together and we did it because we just didn ’ t know any better. we were just having a good time. " he also believes that incubus still hadn ' t found a distinct voice of their own yet, saying in 2022 that they sounded like the offspring from a " crazy orgy " between faith no more, mr. bungle, red hot chili peppers, bjork and other artists. einziger told guitar world in 2011 that the band developed more of their own sound on later albums since they had experienced more of the world through touring by then, and that on s. c. i. e. n. c. e. " [ we sounded ] like what we had been listening to. " for the liner notes, every member except dj lyfe and bassist alex katuni computer networking. coaxial cable is widely used for cable television systems, office buildings, and other work - sites for local area networks. transmission speed ranges from 200 million bits per second to more than 500 million bits per second. itu - t g. hn technology uses existing home wiring ( coaxial cable, phone lines and power lines ) to create a high - speed local area network. twisted pair cabling is used for wired ethernet and other standards. it typically consists of 4 pairs of copper cabling that can be utilized for both voice and data transmission. the use of two wires twisted together helps to reduce crosstalk and electromagnetic induction. the transmission speed ranges from 2 mbit / s to 10 gbit / s. twisted pair cabling comes in two forms : unshielded twisted pair ( utp ) and shielded twisted - pair ( stp ). each form comes in several category ratings, designed for use in various scenarios. an optical fiber is a glass fiber. it carries pulses of light that represent data via lasers and optical amplifiers. some advantages of optical fibers over metal wires are very low transmission loss and immunity to electrical interference. using dense wave division multiplexing, optical fibers can simultaneously carry multiple streams of data on different wavelengths of light, which greatly increases the rate that data can be sent to up to trillions of bits per second. optic fibers can be used for long runs of cable carrying very high data rates, and are used for undersea communications cables to interconnect continents. there are two basic types of fiber optics, single - mode optical fiber ( smf ) and multi - mode optical fiber ( mmf ). single - mode fiber has the advantage of being able to sustain a coherent signal for dozens or even a hundred kilometers. multimode fiber is cheaper to terminate but is limited to a few hundred or even only a few dozens of meters, depending on the data rate and cable grade. = = = wireless = = = network connections can be established wirelessly using radio or other electromagnetic means of communication. terrestrial microwave – terrestrial microwave communication uses earth - based transmitters and receivers resembling satellite dishes. terrestrial microwaves are in the low gigahertz range, which limits all communications to line - of - sight. relay stations are spaced approximately 40 miles ( 64 km ) apart. communications satellites – satellites also communicate via microwave. the satellites are stationed in space, typically in geosynchronous orbit 35, 400 km ( 22, 000 mi ) above the equator. these earth - orbiting systems are Question: Cirrus, stratus, and cumulus are types of what? A) clouds B) plants C) storms D) slopes	A) clouds
Context: the value of excess charge in the kernel of massive body ( and the opposite in sign excess charge at the surface ) caused by the influence of gravitational forces is determined. octet hyperon charge radii are calculated in a chiral constituent quark model including electromagnetic exchange currents between quarks. in impulse approximation one observes a decrease of the hyperon charge radii with increasing strangeness. this effect is reduced by exchange currents. due to exchange currents, the charge radius of the negatively charged hyperons are close to the proton charge radius. charges in the nuclei and the negative charges oscillating about them. more than simple attraction and repulsion, the energies and distributions characterize the availability of an electron to bond to another atom. the chemical bond can be a covalent bond, an ionic bond, a hydrogen bond or just because of van der waals force. each of these kinds of bonds is ascribed to some potential. these potentials create the interactions which hold atoms together in molecules or crystals. in many simple compounds, valence bond theory, the valence shell electron pair repulsion model ( vsepr ), and the concept of oxidation number can be used to explain molecular structure and composition. an ionic bond is formed when a metal loses one or more of its electrons, becoming a positively charged cation, and the electrons are then gained by the non - metal atom, becoming a negatively charged anion. the two oppositely charged ions attract one another, and the ionic bond is the electrostatic force of attraction between them. for example, sodium ( na ), a metal, loses one electron to become an na + cation while chlorine ( cl ), a non - metal, gains this electron to become cl−. the ions are held together due to electrostatic attraction, and that compound sodium chloride ( nacl ), or common table salt, is formed. in a covalent bond, one or more pairs of valence electrons are shared by two atoms : the resulting electrically neutral group of bonded atoms is termed a molecule. atoms will share valence electrons in such a way as to create a noble gas electron configuration ( eight electrons in their outermost shell ) for each atom. atoms that tend to combine in such a way that they each have eight electrons in their valence shell are said to follow the octet rule. however, some elements like hydrogen and lithium need only two electrons in their outermost shell to attain this stable configuration ; these atoms are said to follow the duet rule, and in this way they are reaching the electron configuration of the noble gas helium, which has two electrons in its outer shell. similarly, theories from classical physics can be used to predict many ionic structures. with more complicated compounds, such as metal complexes, valence bond theory is less applicable and alternative approaches, such as the molecular orbital theory, are generally used. = = = energy = = = in the context of chemistry, energy is an attribute of a substance as a consequence of its atomic, molecular or aggregate structure. since a chemical transformation is accompanied by a change ##als force. each of these kinds of bonds is ascribed to some potential. these potentials create the interactions which hold atoms together in molecules or crystals. in many simple compounds, valence bond theory, the valence shell electron pair repulsion model ( vsepr ), and the concept of oxidation number can be used to explain molecular structure and composition. an ionic bond is formed when a metal loses one or more of its electrons, becoming a positively charged cation, and the electrons are then gained by the non - metal atom, becoming a negatively charged anion. the two oppositely charged ions attract one another, and the ionic bond is the electrostatic force of attraction between them. for example, sodium ( na ), a metal, loses one electron to become an na + cation while chlorine ( cl ), a non - metal, gains this electron to become cl−. the ions are held together due to electrostatic attraction, and that compound sodium chloride ( nacl ), or common table salt, is formed. in a covalent bond, one or more pairs of valence electrons are shared by two atoms : the resulting electrically neutral group of bonded atoms is termed a molecule. atoms will share valence electrons in such a way as to create a noble gas electron configuration ( eight electrons in their outermost shell ) for each atom. atoms that tend to combine in such a way that they each have eight electrons in their valence shell are said to follow the octet rule. however, some elements like hydrogen and lithium need only two electrons in their outermost shell to attain this stable configuration ; these atoms are said to follow the duet rule, and in this way they are reaching the electron configuration of the noble gas helium, which has two electrons in its outer shell. similarly, theories from classical physics can be used to predict many ionic structures. with more complicated compounds, such as metal complexes, valence bond theory is less applicable and alternative approaches, such as the molecular orbital theory, are generally used. = = = energy = = = in the context of chemistry, energy is an attribute of a substance as a consequence of its atomic, molecular or aggregate structure. since a chemical transformation is accompanied by a change in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants it is believed that there may have been a large number of black holes formed in the very early universe. these would have quantised masses. a charged ` ` elementary black hole ' ' ( with the minimum possible mass ) can capture electrons, protons and other charged particles to form a ` ` black hole atom ' '. we find the spectrum of such an object with a view to laboratory and astronomical observation of them, and estimate the lifetime of the bound states. there is no limit to the charge of the black hole, which gives us the possibility of observing z > 137 bound states and transitions at the lower continuum. negatively charged black holes can capture protons. for z > 1, the orbiting protons will coalesce to form a nucleus ( after beta - decay of some protons to neutrons ), with a stability curve different to that of free nuclei. in this system there is also the distinct possibility of single quark capture. this leads to the formation of a coloured black hole that plays the role of an extremely heavy quark interacting strongly with the other two quarks. finally we consider atoms formed with much larger black holes. various charge pairings in strongly correlated electron systems are interpreted as quantum entanglement of a composite system. particles in the intermediate phase have a tendency to form the coherent superposition state of the localized state and the itinerant state, which induces the entanglement of both particles in the bipartite subsystems for increasing the entropy of the system. the correction to the entropic coulomb force becomes an immediate cause of charge pairing. the united rest mass and charge of a particle correspond to the two forms of the same regularity of the unified nature of its ultimate structure. each of them contains the electric, weak, strong and the gravitational contributions. as a consequence, the force of an attraction among the two neutrinos and force of their repulsion must be defined from the point of view of any of the existing types of the actions. therefore, to understand the nature of the micro world interaction at the fundamental level, one must use the fact that each of the four types of well known forces includes both a kind of the newton and a kind of the coulomb components. the opinion has been spoken that the existence of the gravitational parts of the united rest mass and charge would imply the availability of such a fifth force which come forwards in the system as a unified whole. , etc. electrostatic control - to avoid the build - up of static electricity in production of paper, plastics, synthetic textiles, etc., a ribbon - shaped source of the alpha emitter 241am can be placed close to the material at the end of the production line. the source ionizes the air to remove electric charges on the material. radioactive tracers - since radioactive isotopes behave, chemically, mostly like the inactive element, the behavior of a certain chemical substance can be followed by tracing the radioactivity. examples : adding a gamma tracer to a gas or liquid in a closed system makes it possible to find a hole in a tube. adding a tracer to the surface of the component of a motor makes it possible to measure wear by measuring the activity of the lubricating oil. oil and gas exploration - nuclear well logging is used to help predict the commercial viability of new or existing wells. the technology involves the use of a neutron or gamma - ray source and a radiation detector which are lowered into boreholes to determine the properties of the surrounding rock such as porosity and lithography. [ 1 ] road construction - nuclear moisture / density gauges are used to determine the density of soils, asphalt, and concrete. typically a cesium - 137 source is used. = = = commercial applications = = = radioluminescence tritium illumination : tritium is used with phosphor in rifle sights to increase nighttime firing accuracy. some runway markers and building exit signs use the same technology, to remain illuminated during blackouts. betavoltaics. smoke detector : an ionization smoke detector includes a tiny mass of radioactive americium - 241, which is a source of alpha radiation. two ionisation chambers are placed next to each other. both contain a small source of 241am that gives rise to a small constant current. one is closed and serves for comparison, the other is open to ambient air ; it has a gridded electrode. when smoke enters the open chamber, the current is disrupted as the smoke particles attach to the charged ions and restore them to a neutral electrical state. this reduces the current in the open chamber. when the current drops below a certain threshold, the alarm is triggered. = = = food processing and agriculture = = = in biology and agriculture, radiation is used to induce mutations to produce new or improved species, such as in atomic gardening. another use in insect control is the sterile insect technique, where male insects are sterilized by radiation and released, so they have strangelets ( stable lumps of quark matter ) can have masses and charges much higher than those of nuclei, but have very low charge - to - mass ratios. this is confirmed in a relativistic thomas - fermi model. the high charge allows astrophysical strangelet acceleration to energies orders of magnitude higher than for protons. in addition, strangelets are much less susceptible to the interactions with the cosmic microwave background that suppress the flux of cosmic ray protons and nuclei above energies of $ 10 ^ { 19 } $ - - $ 10 ^ { 20 } $ ev ( the gzk - cutoff ). this makes strangelets an interesting possibility for explaining ultra - high energy cosmic rays. equivalent of us $ 790 million in state subsidies. the same year, catl introduced its m3p battery, offering a 15 % increase in energy density, reaching 210 wh / kg. the battery replaces the iron in the lithium iron phosphate battery with a combination of magnesium, zinc, and aluminum. later that year, the company announced its shenxing lfp battery. the cathode of shenxing lfp is fully nano - crystallized, which accelerates ion movement and the response to charging signals. the anode ' s second - generation fast ion ring technology increases intercalation channels and shortens intercalation distance. its superconducting electrolyte formula reduces viscosity and improves conductivity. a new separator film reduces resistance. at room temperature, shenxing can charge from 0 to 80 % in 10 minutes and in just 30 minutes at - 10 °c, maintains 0 - 100 kph performance at low temperatures. safety is enhanced by using a safe coating for the electrolyte and the separator. a real - time fault testing system allows safe and fast refueling. ford announced a 2, 500 worker battery plant in marshall, michigan using catl technology. the facility would be a ford subsidiary. making the batteries domestically would enable ford customers to access federal subsidies. the project was paused after lawmakers questioned the tax subsidies. in november 2023, catl and stellantis announced that they are considering the possibility of a joint investment in the form of a joint venture with equivalent contributions. on 7 december 2023, catl and hong kong science and technology parks corporation ( hkstp ) signed a memorandum of understanding to establish a catl research center at the hkstp with investment of over hkd 1. 2 billion. in 2023, the world intellectual property organization ( wipo ) ’ s annual pct review ranked catl ' s number of patent applications published under the pct system as 8th in the world, with 1, 799 patent applications being published during 2023. in april 2024, catl announced tener, a large scale stationary energy storage system. it is claimed to feature all - round safety, zero degradation over five - years and 6. 25 mwh capacity per unit. it incorporates biomimetic sei ( solid electrolyte interphase ) and self - assembled electrolyte technologies. in august 2024, american legislators marco rubio and john moolenaar asked defense secretary lloyd austin to add catl to a list of companies prohibited Question: What is a buildup of electric charges on objects? A) potential B) wattage C) conduction D) static	D) static
Context: by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the two groups are not closely related. the cladistic method takes a systematic approach to characters, distinguishing between those that carry no information about shared evolutionary history – such as those evolved separately in different groups ( homoplasies ) or those left over from ancestors ( plesiomorphies ) – and derived characters, which by which botanists group organisms into categories such as genera or species. biological classification is a form of scientific taxonomy. modern taxonomy is rooted in the work of carl linnaeus, who grouped species according to shared physical characteristics. these groupings have since been revised to align better with the darwinian principle of common descent – grouping organisms by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the ##al nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the two groups are not closely related. the cladistic method takes a systematic approach to characters, distinguishing between those that carry no information about shared evolutionary history – such as those evolved separately in different groups ( homoplasies ) or those left over from ancestors ( plesiomorphies ) – and derived characters, which have been passed down from innovations in a shared ancestor ( apomorphies ). only derived characters, such as the spine - producing areoles of cacti, provide evidence for descent from a common ancestor. the results of cladistic analyses are expressed as cladograms : tree - like diagrams showing the , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive and their competitive or mutualistic interactions with other species. some ecologists even rely on empirical data from indigenous people that is gathered by ethnobotanists. this information can relay a great deal of information on how the land once was thousands of years ago and how it has changed over that time. the goals of plant ecology are to understand the causes of their distribution patterns, productivity, environmental impact, evolution, and responses to environmental change. plants depend on certain edaphic ( soil ) and climatic factors in their environment but can modify these factors too. for example, they can change their environment ' s albedo, increase runoff interception, stabilise mineral soils and develop their organic content, and affect local temperature. plants compete with other organisms in their ecosystem for resources. they interact with their neighbours at a variety of spatial scales in groups, populations and communities that collectively constitute vegetation. regions with characteristic vegetation types and dominant plants as well as similar abiotic and biotic factors, climate, and geography make up biomes like tundra or tropical rainforest. herbivores eat plants, but plants can defend themselves and some species are parasitic or even carnivorous. other organisms form mutually beneficial relationships with plants. for example, mycorrhizal fungi and rhizobia provide plants with nutrients in exchange for food, ants are recruited by ant plants to provide protection, honey bees, bats and other animals pollinate flowers and humans and other animals act as dispersal vectors to spread spores and seeds. = = = plants, climate and environmental change = = = plant responses to climate and other environmental changes can inform our understanding of how these changes affect ecosystem function and productivity. for example, plant phenology can be a useful proxy for temperature in historical climatology, and the biological impact of climate change and global warming. palynology, the analysis of fossil pollen deposits in sediments from thousands or millions of years ago allows the reconstruction of past climates. estimates of atmospheric co2 concentrations since the palaeozoic have been obtained from stomatal densities and the leaf shapes and sizes of ancient land plants. ozone depletion can expose plants to higher levels of ultraviolet radiation - b ( uv - b ), resulting in lower growth rates. moreover, information from studies of community ecology, plant systematics, and taxonomy is essential to understanding vegetation change, habitat destruction and species extinction. = = genetics = = inheritance in plants follows the same fundamental principles of genetics as in other multicellular organisms. gregor mendel discovered the genetic laws of inheritance by studying eat them. plants and other photosynthetic organisms are at the base of most food chains because they use the energy from the sun and nutrients from the soil and atmosphere, converting them into a form that can be used by animals. this is what ecologists call the first trophic level. the modern forms of the major staple foods, such as hemp, teff, maize, rice, wheat and other cereal grasses, pulses, bananas and plantains, as well as hemp, flax and cotton grown for their fibres, are the outcome of prehistoric selection over thousands of years from among wild ancestral plants with the most desirable characteristics. botanists study how plants produce food and how to increase yields, for example through plant breeding, making their work important to humanity ' s ability to feed the world and provide food security for future generations. botanists also study weeds, which are a considerable problem in agriculture, and the biology and control of plant pathogens in agriculture and natural ecosystems. ethnobotany is the study of the relationships between plants and people. when applied to the investigation of historical plant – people relationships ethnobotany may be referred to as archaeobotany or palaeoethnobotany. some of the earliest plant - people relationships arose between the indigenous people of canada in identifying edible plants from inedible plants. this relationship the indigenous people had with plants was recorded by ethnobotanists. = = plant biochemistry = = plant biochemistry is the study of the chemical processes used by plants. some of these processes are used in their primary metabolism like the photosynthetic calvin cycle and crassulacean acid metabolism. others make specialised materials like the cellulose and lignin used to build their bodies, and secondary products like resins and aroma compounds. plants and various other groups of photosynthetic eukaryotes collectively known as " algae " have unique organelles known as chloroplasts. chloroplasts are thought to be descended from cyanobacteria that formed endosymbiotic relationships with ancient plant and algal ancestors. chloroplasts and cyanobacteria contain the blue - green pigment chlorophyll a. chlorophyll a ( as well as its plant and green algal - specific cousin chlorophyll b ) absorbs light in the blue - violet and orange / red parts of the spectrum while reflecting and transmitting the green light that we see as the characteristic colour kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the two groups are not closely related. the cladistic method takes a systematic approach to characters, distinguishing between those that carry no information about shared evolutionary history – such as those evolved separately in different groups ( homoplasies ) or those left over from ancestors ( plesiomorphies ) – and derived characters, which have been passed down from innovations in a shared ancestor ( apomorphies ). only derived characters, such as the spine - producing areoles of cacti, provide evidence for descent from a common ancestor. the results of cladistic analyses are expressed as cladograms : tree - like diagrams showing the pattern of evolutionary branching and descent. from the 1990s onwards, the predominant approach to constructing phylogenies for living plants has been molecular phylogenetics, which uses molecular characters, particularly dna sequences, rather than morphological characters like the presence or absence of spines and areoles. the difference is that the genetic code itself is used one of the greatest discoveries of modern times is that of the expanding universe, almost invariably attributed to hubble ( 1929 ). what is not widely known is that the original treatise by lemaitre ( 1927 ) contained a rich fusion of both theory and of observation. stiglers law of eponymy is yet again affirmed : no scientific discovery is named after its original discoverer ( merton, 1957 ). an appeal is made for a lemaitre telescope, to honour the discoverer of the expanding universe. organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mitochondria and chloroplasts, both of which are now part of modern - day eukaryotic cells. the major lineages of eukaryotes diversified in the precambrian about 1. 5 billion years ago and can be classified into eight major clades : alveolates, excavates, stramenopiles, plants, rhizarians, amoebozoans, fungi, and animals. five of these clades are collectively known as protists, which are mostly microscopic eukaryotic organisms that are not plants, fungi, or animals. while it is likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, . species boundaries in plants may be weaker than in animals, and cross species hybrids are often possible. a familiar example is peppermint, mentha × piperita, a sterile hybrid between mentha aquatica and spearmint, mentha spicata. the many cultivated varieties of wheat are the result of multiple inter - and intra - specific crosses between wild species and their hybrids. angiosperms with monoecious flowers often have self - incompatibility mechanisms that operate between the pollen and stigma so that the pollen either fails to reach the stigma or fails to germinate and produce male gametes. this is one of several methods used by plants to promote outcrossing. in many land plants the male and female gametes are produced by separate individuals. these species are said to be dioecious when referring to vascular plant sporophytes and dioicous when referring to bryophyte gametophytes. charles darwin in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in Question: Where do you find the greatest biodiversity? A) in shallow lakes B) at the poles C) in the tropics D) in the tundra	C) in the tropics
Context: and still use the same basic biological methods. in brewing, malted grains ( containing enzymes ) convert starch from grains into sugar and then adding specific yeasts to produce beer. in this process, carbohydrates in the grains broke down into alcohols, such as ethanol. later, other cultures produced the process of lactic acid fermentation, which produced other preserved foods, such as soy sauce. fermentation was also used in this time period to produce leavened bread. although the process of fermentation was not fully understood until louis pasteur ' s work in 1857, it is still the first use of biotechnology to convert a food source into another form. before the time of charles darwin ' s work and life, animal and plant scientists had already used selective breeding. darwin added to that body of work with his scientific observations about the ability of science to change species. these accounts contributed to darwin ' s theory of natural selection. for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united kingdom desperately needed to manufacture explosives during world war i. biotechnology has also led to the development of antibiotics. in 1928, alexander fleming discovered the mold penicillium. his work led to the purification of the antibiotic formed by the mold by howard florey, ernst boris chain and norman heatley – to form what we today know as penicillin. in 1940, penicillin became available for medicinal use to treat bacterial infections in humans. the field of modern biotechnology is generally thought of as having been born in 1971 when paul berg ' s ( stanford ) experiments in gene splicing had early success. herbert w. boyer ( univ. calif. at san francisco ) and stanley n. cohen ( stanford ) significantly advanced the new technology in 1972 by transferring genetic material into a bacterium, such that the imported material would be reproduced. the commercial viability of a biotechnology industry was significantly expanded on june 16, 1980, when the united states the broad definition of " utilizing a biotechnological system to make products ". indeed, the cultivation of plants may be viewed as the earliest biotechnological enterprise. agriculture has been theorized to have become the dominant way of producing food since the neolithic revolution. through early biotechnology, the earliest farmers selected and bred the best - suited crops ( e. g., those with the highest yields ) to produce enough food to support a growing population. as crops and fields became increasingly large and difficult to maintain, it was discovered that specific organisms and their by - products could effectively fertilize, restore nitrogen, and control pests. throughout the history of agriculture, farmers have inadvertently altered the genetics of their crops through introducing them to new environments and breeding them with other plants — one of the first forms of biotechnology. these processes also were included in early fermentation of beer. these processes were introduced in early mesopotamia, egypt, china and india, and still use the same basic biological methods. in brewing, malted grains ( containing enzymes ) convert starch from grains into sugar and then adding specific yeasts to produce beer. in this process, carbohydrates in the grains broke down into alcohols, such as ethanol. later, other cultures produced the process of lactic acid fermentation, which produced other preserved foods, such as soy sauce. fermentation was also used in this time period to produce leavened bread. although the process of fermentation was not fully understood until louis pasteur ' s work in 1857, it is still the first use of biotechnology to convert a food source into another form. before the time of charles darwin ' s work and life, animal and plant scientists had already used selective breeding. darwin added to that body of work with his scientific observations about the ability of science to change species. these accounts contributed to darwin ' s theory of natural selection. for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united process of lactic acid fermentation, which produced other preserved foods, such as soy sauce. fermentation was also used in this time period to produce leavened bread. although the process of fermentation was not fully understood until louis pasteur ' s work in 1857, it is still the first use of biotechnology to convert a food source into another form. before the time of charles darwin ' s work and life, animal and plant scientists had already used selective breeding. darwin added to that body of work with his scientific observations about the ability of science to change species. these accounts contributed to darwin ' s theory of natural selection. for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united kingdom desperately needed to manufacture explosives during world war i. biotechnology has also led to the development of antibiotics. in 1928, alexander fleming discovered the mold penicillium. his work led to the purification of the antibiotic formed by the mold by howard florey, ernst boris chain and norman heatley – to form what we today know as penicillin. in 1940, penicillin became available for medicinal use to treat bacterial infections in humans. the field of modern biotechnology is generally thought of as having been born in 1971 when paul berg ' s ( stanford ) experiments in gene splicing had early success. herbert w. boyer ( univ. calif. at san francisco ) and stanley n. cohen ( stanford ) significantly advanced the new technology in 1972 by transferring genetic material into a bacterium, such that the imported material would be reproduced. the commercial viability of a biotechnology industry was significantly expanded on june 16, 1980, when the united states supreme court ruled that a genetically modified microorganism could be patented in the case of diamond v. chakrabarty. indian - born ananda chakrabarty, working for general electric, had modified a bacterium ( of the genus pseudomonas ) capable of breaking down crude oil, which he proposed to . throughout the history of agriculture, farmers have inadvertently altered the genetics of their crops through introducing them to new environments and breeding them with other plants — one of the first forms of biotechnology. these processes also were included in early fermentation of beer. these processes were introduced in early mesopotamia, egypt, china and india, and still use the same basic biological methods. in brewing, malted grains ( containing enzymes ) convert starch from grains into sugar and then adding specific yeasts to produce beer. in this process, carbohydrates in the grains broke down into alcohols, such as ethanol. later, other cultures produced the process of lactic acid fermentation, which produced other preserved foods, such as soy sauce. fermentation was also used in this time period to produce leavened bread. although the process of fermentation was not fully understood until louis pasteur ' s work in 1857, it is still the first use of biotechnology to convert a food source into another form. before the time of charles darwin ' s work and life, animal and plant scientists had already used selective breeding. darwin added to that body of work with his scientific observations about the ability of science to change species. these accounts contributed to darwin ' s theory of natural selection. for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united kingdom desperately needed to manufacture explosives during world war i. biotechnology has also led to the development of antibiotics. in 1928, alexander fleming discovered the mold penicillium. his work led to the purification of the antibiotic formed by the mold by howard florey, ernst boris chain and norman heatley – to form what we today know as penicillin. in 1940, penicillin became available for medicinal use to treat bacterial infections in humans. the field of modern biotechnology is generally thought of as having been born in 1971 when paul berg ' s ( stanford ) experiments in gene splicing had early success. herbert w. boyer . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = the best - suited crops ( e. g., those with the highest yields ) to produce enough food to support a growing population. as crops and fields became increasingly large and difficult to maintain, it was discovered that specific organisms and their by - products could effectively fertilize, restore nitrogen, and control pests. throughout the history of agriculture, farmers have inadvertently altered the genetics of their crops through introducing them to new environments and breeding them with other plants — one of the first forms of biotechnology. these processes also were included in early fermentation of beer. these processes were introduced in early mesopotamia, egypt, china and india, and still use the same basic biological methods. in brewing, malted grains ( containing enzymes ) convert starch from grains into sugar and then adding specific yeasts to produce beer. in this process, carbohydrates in the grains broke down into alcohols, such as ethanol. later, other cultures produced the process of lactic acid fermentation, which produced other preserved foods, such as soy sauce. fermentation was also used in this time period to produce leavened bread. although the process of fermentation was not fully understood until louis pasteur ' s work in 1857, it is still the first use of biotechnology to convert a food source into another form. before the time of charles darwin ' s work and life, animal and plant scientists had already used selective breeding. darwin added to that body of work with his scientific observations about the ability of science to change species. these accounts contributed to darwin ' s theory of natural selection. for thousands of years, humans have used selective breeding to improve the production of crops and livestock to use them for food. in selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. for example, this technique was used with corn to produce the largest and sweetest crops. in the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. in 1917, chaim weizmann first used a pure microbiological culture in an industrial process, that of manufacturing corn starch using clostridium acetobutylicum, to produce acetone, which the united kingdom desperately needed to manufacture explosives during world war i. biotechnology has also led to the development of antibiotics. in 1928, alexander fleming discovered the mold penicillium. his work led to the purification of the antibiotic formed by the mold by howard florey, ernst boris chain and norman heatley – to form use less energy than conventional thermal separation processes such as distillation, sublimation or crystallization. the separation process is purely physical and both fractions ( permeate and retentate ) can be obtained as useful products. cold separation using membrane technology is widely used in the food technology, biotechnology and pharmaceutical industries. furthermore, using membranes enables separations to take place that would be impossible using thermal separation methods. for example, it is impossible to separate the constituents of azeotropic liquids or solutes which form isomorphic crystals by distillation or recrystallization but such separations can be achieved using membrane technology. depending on the type of membrane, the selective separation of certain individual substances or substance mixtures is possible. important technical applications include the production of drinking water by reverse osmosis. in waste water treatment, membrane technology is becoming increasingly important. ultra / microfiltration can be very effective in removing colloids and macromolecules from wastewater. this is needed if wastewater is discharged into sensitive waters especially those designated for contact water sports and recreation. about half of the market is in medical applications such as artificial kidneys to remove toxic substances by hemodialysis and as artificial lung for bubble - free supply of oxygen in the blood. the importance of membrane technology is growing in the field of environmental protection ( nano - mem - pro ippc database ). even in modern energy recovery techniques, membranes are increasingly used, for example in fuel cells and in osmotic power plants. = = mass transfer = = two basic models can be distinguished for mass transfer through the membrane : the solution - diffusion model and the hydrodynamic model. in real membranes, these two transport mechanisms certainly occur side by side, especially during ultra - filtration. = = = solution - diffusion model = = = in the solution - diffusion model, transport occurs only by diffusion. the component that needs to be transported must first be dissolved in the membrane. the general approach of the solution - diffusion model is to assume that the chemical potential of the feed and permeate fluids are in equilibrium with the adjacent membrane surfaces such that appropriate expressions for the chemical potential in the fluid and membrane phases can be equated at the solution - membrane interface. this principle is more important for dense membranes without natural pores such as those used for reverse osmosis and in fuel cells. during the filtration process a boundary layer forms on the membrane. this concentration gradient is created by molecules which cannot pass through the membrane. the a wide range of opiate painkillers like heroin are obtained by chemical modification of morphine obtained from the opium poppy. popular stimulants come from plants, such as caffeine from coffee, tea and chocolate, and nicotine from tobacco. most alcoholic beverages come from fermentation of carbohydrate - rich plant products such as barley ( beer ), rice ( sake ) and grapes ( wine ). native americans have used various plants as ways of treating illness or disease for thousands of years. this knowledge native americans have on plants has been recorded by enthnobotanists and then in turn has been used by pharmaceutical companies as a way of drug discovery. plants can synthesise coloured dyes and pigments such as the anthocyanins responsible for the red colour of red wine, yellow weld and blue woad used together to produce lincoln green, indoxyl, source of the blue dye indigo traditionally used to dye denim and the artist ' s pigments gamboge and rose madder. sugar, starch, cotton, linen, hemp, some types of rope, wood and particle boards, papyrus and paper, vegetable oils, wax, and natural rubber are examples of commercially important materials made from plant tissues or their secondary products. charcoal, a pure form of carbon made by pyrolysis of wood, has a long history as a metal - smelting fuel, as a filter material and adsorbent and as an artist ' s material and is one of the three ingredients of gunpowder. cellulose, the world ' s most abundant organic polymer, can be converted into energy, fuels, materials and chemical feedstock. products made from cellulose include rayon and cellophane, wallpaper paste, biobutanol and gun cotton. sugarcane, rapeseed and soy are some of the plants with a highly fermentable sugar or oil content that are used as sources of biofuels, important alternatives to fossil fuels, such as biodiesel. sweetgrass was used by native americans to ward off bugs like mosquitoes. these bug repelling properties of sweetgrass were later found by the american chemical society in the molecules phytol and coumarin. = = plant ecology = = plant ecology is the science of the functional relationships between plants and their habitats – the environments where they complete their life cycles. plant ecologists study the composition of local and regional floras, their biodiversity, genetic diversity and fitness, the adaptation of plants to their environment, inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase which constitutes anywhere from 30 % [ m / m ] to 90 % [ m / m ] of its composition by volume, yielding an array of materials with interesting thermomechanical properties. in the processing of glass - ceramics, molten glass is cooled down gradually before reheating and annealing. in this heat industrial applications. this branch of biotechnology is the most used for the industries of refining and combustion principally on the production of bio - oils with photosynthetic micro - algae. green biotechnology is biotechnology applied to agricultural processes. an example would be the selection and domestication of plants via micropropagation. another example is the designing of transgenic plants to grow under specific environments in the presence ( or absence ) of chemicals. one hope is that green biotechnology might produce more environmentally friendly solutions than traditional industrial agriculture. an example of this is the engineering of a plant to express a pesticide, thereby ending the need of external application of pesticides. an example of this would be bt corn. whether or not green biotechnology products such as this are ultimately more environmentally friendly is a topic of considerable debate. it is commonly considered as the next phase of green revolution, which can be seen as a platform to eradicate world hunger by using technologies which enable the production of more fertile and resistant, towards biotic and abiotic stress, plants and ensures application of environmentally friendly fertilizers and the use of biopesticides, it is mainly focused on the development of agriculture. on the other hand, some of the uses of green biotechnology involve microorganisms to clean and reduce waste. red biotechnology is the use of biotechnology in the medical and pharmaceutical industries, and health preservation. this branch involves the production of vaccines and antibiotics, regenerative therapies, creation of artificial organs and new diagnostics of diseases. as well as the development of hormones, stem cells, antibodies, sirna and diagnostic tests. white biotechnology, also known as industrial biotechnology, is biotechnology applied to industrial processes. an example is the designing of an organism to produce a useful chemical. another example is the using of enzymes as industrial catalysts to either produce valuable chemicals or destroy hazardous / polluting chemicals. white biotechnology tends to consume less in resources than traditional processes used to produce industrial goods. yellow biotechnology refers to the use of biotechnology in food production ( food industry ), for example in making wine ( winemaking ), cheese ( cheesemaking ), and beer ( brewing ) by fermentation. it has also been used to refer to biotechnology applied to insects. this includes biotechnology - based approaches for the control of harmful insects, the characterisation and utilisation of active ingredients or genes of insects for research, or application in agriculture and medicine and various other approaches. gray biotechnology is dedicated to environmental applications, and focused on the maintenance of biodiversity and the remotion of poll Question: The ostwald process is the commercial method for producing what? A) citric acid B) chlorine C) nitric acid D) deoxyribonucleic acid	C) nitric acid
Context: into seven out of approximately 20 human test subjects as part of a long - term experiment. cartilage : lab - grown cartilage, cultured in vitro on a scaffold, was successfully used as an autologous transplant to repair patients ' knees. scaffold - free cartilage : cartilage generated without the use of exogenous scaffold material. in this methodology, all material in the construct is cellular produced directly by the cells. bioartificial heart : doris taylor ' s lab constructed a biocompatible rat heart by re - cellularising a de - cellularised rat heart. this scaffold and cells were placed in a bioreactor, where it matured to become a partially or fully transplantable organ. the work was called a " landmark ". the lab first stripped the cells away from a rat heart ( a process called " decellularization " ) and then injected rat stem cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase which constitutes anywhere from 30 % [ m / m ] to 90 % [ m / m ] of its composition by volume, yielding an array of materials with interesting thermomechanical properties. in the processing of glass - ceramics, molten glass is cooled down gradually before reheating and annealing. in this heat ##tronics, the science of using mechanical devices with human muscular, musculoskeletal, and nervous systems to assist or enhance motor control lost by trauma, disease, or defect. prostheses are typically used to replace parts lost by injury ( traumatic ) or missing from birth ( congenital ) or to supplement defective body parts. inside the body, artificial heart valves are in common use with artificial hearts and lungs seeing less common use but under active technology development. other medical devices and aids that can be considered prosthetics include hearing aids, artificial eyes, palatal obturator, gastric bands, and dentures. prostheses are specifically not orthoses, although given certain circumstances a prosthesis might end up performing some or all of the same functionary benefits as an orthosis. prostheses are technically the complete finished item. for instance, a c - leg knee alone is not a prosthesis, but only a prosthetic component. the complete prosthesis would consist of the attachment system to the residual limb – usually a " socket ", and all the attachment hardware components all the way down to and including the terminal device. despite the technical difference, the terms are often used interchangeably. the terms " prosthetic " and " orthotic " are adjectives used to describe devices such as a prosthetic knee. the terms " prosthetics " and " orthotics " are used to describe the respective allied health fields. an occupational therapist ' s role in prosthetics include therapy, training and evaluations. prosthetic training includes orientation to prosthetics components and terminology, donning and doffing, wearing schedule, and how to care for residual limb and the prosthesis. = = = exoskeletons = = = a powered exoskeleton is a wearable mobile machine that is powered by a system of electric motors, pneumatics, levers, hydraulics, or a combination of technologies that allow for limb movement with increased strength and endurance. its design aims to provide back support, sense the user ' s motion, and send a signal to motors which manage the gears. the exoskeleton supports the shoulder, waist and thigh, and assists movement for lifting and holding heavy items, while lowering back stress. = = = adaptive seating and positioning = = = people with balance and motor function challenges often need specialized equipment to sit or stand safely and securely. this equipment is frequently ; austrian experts have established that the wheel is between 5, 100 and 5, 350 years old. the invention of the wheel revolutionized trade and war. it did not take long to discover that wheeled wagons could be used to carry heavy loads. the ancient sumerians used a potter ' s wheel and may have invented it. a stone pottery wheel found in the city - state of ur dates to around 3, 429 bce, and even older fragments of wheel - thrown pottery have been found in the same area. fast ( rotary ) potters ' wheels enabled early mass production of pottery, but it was the use of the wheel as a transformer of energy ( through water wheels, windmills, and even treadmills ) that revolutionized the application of nonhuman power sources. the first two - wheeled carts were derived from travois and were first used in mesopotamia and iran in around 3, 000 bce. the oldest known constructed roadways are the stone - paved streets of the city - state of ur, dating to c. 4, 000 bce, and timber roads leading through the swamps of glastonbury, england, dating to around the same period. the first long - distance road, which came into use around 3, 500 bce, spanned 2, 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans also had a complex system of aqueducts, which were used to transport water across long distances. the first roman aqueduct was built in 312 bce. the eleventh and final ancient roman aqueduct was built in 226 ce. put together, the roman aqueducts extended over 450 km, but less than 70 km of this was above ground 28 size spectra of extensive air showers from 7 different experiments are analysed consistently. they are fitted by adjusting either 4 or 5 parameters : knee position, power law exponents above and below the knee, overall intensity and, in addition, a parameter describing the smoothness of the bend. the residuals are then normalized to the same knee position and averaged. when 5 parameters are employed no systematic deviation from a single smooth knee is apparent at the 1 % level up to a factor of 4 above the knee. at larger shower sizes a moderately significant deviation can be seen whose shape and position are compatible with a second knee caused by iron group nuclei. as a traditional tool of external assistance, crutches play an important role in society. they have a wide range of applications to help either the elderly and disabled to walk or to treat certain illnesses or for post - operative rehabilitation. but there are many different types of crutches, including shoulder crutches and elbow crutches. how to choose has become an issue that deserves to be debated. because while crutches help people walk, they also have an impact on the body. inappropriate choice of crutches or long - term misuse can lead to problems such as scoliosis. previous studies were mainly experimental measurements or the construction of dynamic models to calculate the load on joints with crutches. these studies focus only on the level of the joints, ignoring the role that muscles play in this process. although some also take into account the degree of muscle activation, there is still a lack of quantitative analysis. the traditional dynamic model can be used to calculate the load on each joint. however, due to the activation of the muscle, this situation only causes part of the load transmitted to the joint, and the work of the chair will compensate the other part of the load. analysis at the muscle level allows a better understanding of the impact of crutches on the body. by comparing the levels of activation of the trunk muscles, it was found that the use of crutches for walking, especially a single crutch, can cause a large difference in the activation of the back muscles on the left and right sides, and this difference will cause muscle degeneration for a long time, leading to scoliosis. in this article taking scoliosis as an example, by analyzing the muscles around the spine, we can better understand the pathology and can better prevent diseases. the objective of this article is to analyze normal walking compared to walking with one or two crutches using opensim software to obtain the degree of activation of different muscles in order to analyze the impact of crutches on the body. time estimates range from 5, 500 to 3, 000 bce with most experts putting it closer to 4, 000 bce. the oldest artifacts with drawings depicting wheeled carts date from about 3, 500 bce. more recently, the oldest - known wooden wheel in the world as of 2024 was found in the ljubljana marsh of slovenia ; austrian experts have established that the wheel is between 5, 100 and 5, 350 years old. the invention of the wheel revolutionized trade and war. it did not take long to discover that wheeled wagons could be used to carry heavy loads. the ancient sumerians used a potter ' s wheel and may have invented it. a stone pottery wheel found in the city - state of ur dates to around 3, 429 bce, and even older fragments of wheel - thrown pottery have been found in the same area. fast ( rotary ) potters ' wheels enabled early mass production of pottery, but it was the use of the wheel as a transformer of energy ( through water wheels, windmills, and even treadmills ) that revolutionized the application of nonhuman power sources. the first two - wheeled carts were derived from travois and were first used in mesopotamia and iran in around 3, 000 bce. the oldest known constructed roadways are the stone - paved streets of the city - state of ur, dating to c. 4, 000 bce, and timber roads leading through the swamps of glastonbury, england, dating to around the same period. the first long - distance road, which came into use around 3, 500 bce, spanned 2, 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans it. a stone pottery wheel found in the city - state of ur dates to around 3, 429 bce, and even older fragments of wheel - thrown pottery have been found in the same area. fast ( rotary ) potters ' wheels enabled early mass production of pottery, but it was the use of the wheel as a transformer of energy ( through water wheels, windmills, and even treadmills ) that revolutionized the application of nonhuman power sources. the first two - wheeled carts were derived from travois and were first used in mesopotamia and iran in around 3, 000 bce. the oldest known constructed roadways are the stone - paved streets of the city - state of ur, dating to c. 4, 000 bce, and timber roads leading through the swamps of glastonbury, england, dating to around the same period. the first long - distance road, which came into use around 3, 500 bce, spanned 2, 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans also had a complex system of aqueducts, which were used to transport water across long distances. the first roman aqueduct was built in 312 bce. the eleventh and final ancient roman aqueduct was built in 226 ce. put together, the roman aqueducts extended over 450 km, but less than 70 km of this was above ground and supported by arches. = = = pre - modern = = = innovations continued through the middle ages with the introduction of silk production ( in asia and later europe ), the horse collar, and horseshoes. simple machines ( such as the lever, the screw, and the pulley ) were combined into more complicated tools ##lling, pipe jacking and other operations. a caisson is sunk by self - weight, concrete or water ballast placed on top, or by hydraulic jacks. the leading edge ( or cutting shoe ) of the caisson is sloped out at a sharp angle to aid sinking in a vertical manner ; it is usually made of steel. the shoe is generally wider than the caisson to reduce friction, and the leading edge may be supplied with pressurised bentonite slurry, which swells in water, stabilizing settlement by filling depressions and voids. an open caisson may fill with water during sinking. the material is excavated by clamshell excavator bucket on crane. the formation level subsoil may still not be suitable for excavation or bearing capacity. the water in the caisson ( due to a high water table ) balances the upthrust forces of the soft soils underneath. if dewatered, the base may " pipe " or " boil ", causing the caisson to sink. to combat this problem, piles may be driven from the surface to act as : load - bearing walls, in that they transmit loads to deeper soils. anchors, in that they resist flotation because of the friction at the interface between their surfaces and the surrounding earth into which they have been driven. h - beam sections ( typical column sections, due to resistance to bending in all axis ) may be driven at angles " raked " to rock or other firmer soils ; the h - beams are left extended above the base. a reinforced concrete plug may be placed under the water, a process known as tremie concrete placement. when the caisson is dewatered, this plug acts as a pile cap, resisting the upward forces of the subsoil. = = = monolithic = = = a monolithic caisson ( or simply a monolith ) is larger than the other types of caisson, but similar to open caissons. such caissons are often found in quay walls, where resistance to impact from ships is required. = = = pneumatic = = = shallow caissons may be open to the air, whereas pneumatic caissons ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called Question: What includes the bones and cartilage? A) skull B) fossil C) lungs D) skeleton	D) skeleton
Context: why has the problematic of complexity appeared so late? and why would it be justified? ##simal cube of material relative to a reference configuration. mechanical strains are caused by mechanical stress, see stress - strain curve. the relationship between stress and strain is generally linear and reversible up until the yield point and the deformation is elastic. elasticity in materials occurs when applied stress does not surpass the energy required to break molecular bonds, allowing the material to deform reversibly and return to its original shape once the stress is removed. the linear relationship for a material is known as young ' s modulus. above the yield point, some degree of permanent distortion remains after unloading and is termed plastic deformation. the determination of the stress and strain throughout a solid object is given by the field of strength of materials and for a structure by structural analysis. in the above figure, it can be seen that the compressive loading ( indicated by the arrow ) has caused deformation in the cylinder so that the original shape ( dashed lines ) has changed ( deformed ) into one with bulging sides. the sides bulge because the material, although strong enough to not crack or otherwise fail, is not strong enough to support the load without change. as a result, the material is forced out laterally. internal forces ( in this case at right angles to the deformation ) resist the applied load. = = types of deformation = = depending on the type of material, size and geometry of the object, and the forces applied, various types of deformation may result. the image to the right shows the engineering stress vs. strain diagram for a typical ductile material such as steel. different deformation modes may occur under different conditions, as can be depicted using a deformation mechanism map. permanent deformation is irreversible ; the deformation stays even after removal of the applied forces, while the temporary deformation is recoverable as it disappears after the removal of applied forces. temporary deformation is also called elastic deformation, while the permanent deformation is called plastic deformation. = = = elastic deformation = = = the study of temporary or elastic deformation in the case of engineering strain is applied to materials used in mechanical and structural engineering, such as concrete and steel, which are subjected to very small deformations. engineering strain is modeled by infinitesimal strain theory, also called small strain theory, small deformation theory, small displacement theory, or small displacement - gradient theory where strains and rotations are both small. for some materials, e. g. elastomers and polymers, subjected to large deformations, the engineering definition of strain is not applicable, e. g. typical engineering strains genetic engineering takes the gene directly from one organism and delivers it to the other. this is much faster, can be used to insert any genes from any organism ( even ones from different domains ) and prevents other undesirable genes from also being added. genetic engineering could potentially fix severe genetic disorders in humans by replacing the defective gene with a functioning one. it is an important tool in research that allows the function of specific genes to be studied. drugs, vaccines and other products have been harvested from organisms engineered to produce them. crops have been developed that aid food security by increasing yield, nutritional value and tolerance to environmental stresses. the dna can be introduced directly into the host organism or into a cell that is then fused or hybridised with the host. this relies on recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro - injection, macro - injection or micro - encapsulation. genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. however, some broad definitions of genetic engineering include selective breeding. cloning and stem cell research, although not considered genetic engineering, are closely related and genetic engineering can be used within them. synthetic biology is an emerging discipline that takes genetic engineering a step further by introducing artificially synthesised material into an organism. plants, animals or microorganisms that have been changed through genetic engineering are termed genetically modified organisms or gmos. if genetic material from another species is added to the host, the resulting organism is called transgenic. if genetic material from the same species or a species that can naturally breed with the host is used the resulting organism is called cisgenic. if genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a knockout organism. in europe genetic modification is synonymous with genetic engineering while within the united states of america and canada genetic modification can also be used to refer to more conventional breeding methods. = = history = = humans have altered the genomes of species for thousands of years through selective breeding, or artificial selection : 1 : 1 as contrasted with natural selection. more recently, mutation breeding has used exposure to chemicals or radiation to produce a high frequency of random mutations, for selective breeding purposes. genetic engineering as the direct manipulation of dna by humans outside breeding and conjure is an automated modelling tool for constraint programming. in this documentation, you will find the following : a brief introduction to conjure, installation instructions, a description of how to use conjure through its command line user interface, a list of conjure ' s features, a description of conjure ' s input language essence, and a collection of simple demonstrations of conjure ' s use. defective gene with a functioning one. it is an important tool in research that allows the function of specific genes to be studied. drugs, vaccines and other products have been harvested from organisms engineered to produce them. crops have been developed that aid food security by increasing yield, nutritional value and tolerance to environmental stresses. the dna can be introduced directly into the host organism or into a cell that is then fused or hybridised with the host. this relies on recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro - injection, macro - injection or micro - encapsulation. genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. however, some broad definitions of genetic engineering include selective breeding. cloning and stem cell research, although not considered genetic engineering, are closely related and genetic engineering can be used within them. synthetic biology is an emerging discipline that takes genetic engineering a step further by introducing artificially synthesised material into an organism. plants, animals or microorganisms that have been changed through genetic engineering are termed genetically modified organisms or gmos. if genetic material from another species is added to the host, the resulting organism is called transgenic. if genetic material from the same species or a species that can naturally breed with the host is used the resulting organism is called cisgenic. if genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a knockout organism. in europe genetic modification is synonymous with genetic engineering while within the united states of america and canada genetic modification can also be used to refer to more conventional breeding methods. = = history = = humans have altered the genomes of species for thousands of years through selective breeding, or artificial selection : 1 : 1 as contrasted with natural selection. more recently, mutation breeding has used exposure to chemicals or radiation to produce a high frequency of random mutations, for selective breeding purposes. genetic engineering as the direct manipulation of dna by humans outside breeding and mutations has only existed since the 1970s. the term " genetic engineering " was coined by the russian - born geneticist nikolay timofeev - ressovsky in his 1934 paper " the experimental production of mutations ", published in the british journal biological reviews. jack williamson used the term in his science fiction novel dragon ' of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive their mechanical properties. = = tissue culture = = in many cases, creation of functional tissues and biological structures in vitro requires extensive culturing to promote survival, growth and inducement of functionality. in general, the basic requirements of cells must be maintained in culture, which include oxygen, ph, humidity, temperature, nutrients and osmotic pressure maintenance. tissue engineered cultures also present additional problems in maintaining culture conditions. in standard cell culture, diffusion is often the sole means of nutrient and metabolite transport. however, as a culture becomes larger and more complex, such as the case with engineered organs and whole tissues, other mechanisms must be employed to maintain the culture, such as the creation of capillary networks within the tissue. another issue with tissue culture is introducing the proper factors or stimuli required to induce functionality. in many cases, simple maintenance culture is not sufficient. growth factors, hormones, specific metabolites or nutrients, chemical and physical stimuli are sometimes required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can ##physical processes which take place in human beings as they make sense of information received through the visual system. the subject of the image. when developing an imaging system, designers must consider the observables associated with the subjects which will be imaged. these observables generally take the form of emitted or reflected energy, such as electromagnetic energy or mechanical energy. the capture device. once the observables associated with the subject are characterized, designers can then identify and integrate the technologies needed to capture those observables. for example, in the case of consumer digital cameras, those technologies include optics for collecting energy in the visible portion of the electromagnetic spectrum, and electronic detectors for converting the electromagnetic energy into an electronic signal. the processor. for all digital imaging systems, the electronic signals produced by the capture device must be manipulated by an algorithm which formats the signals so they can be displayed as an image. in practice, there are often multiple processors involved in the creation of a digital image. the display. the display takes the electronic signals which have been manipulated by the processor and renders them on some visual medium. examples include paper ( for printed, or " hard copy " images ), television, computer monitor, or projector. note that some imaging scientists will include additional " links " in their description of the imaging chain. for example, some will include the " source " of the energy which " illuminates " or interacts with the subject of the image. others will include storage and / or transmission systems. = = subfields = = subfields within imaging science include : image processing, computer vision, 3d computer graphics, animations, atmospheric optics, astronomical imaging, biological imaging, digital image restoration, digital imaging, color science, digital photography, holography, magnetic resonance imaging, medical imaging, microdensitometry, optics, photography, remote sensing, radar imaging, radiometry, silver halide, ultrasound imaging, photoacoustic imaging, thermal imaging, visual perception, and various printing technologies. = = methodologies = = acoustic imaging coherent imaging uses an active coherent illumination source, such as in radar, synthetic aperture radar ( sar ), medical ultrasound and optical coherence tomography ; non - coherent imaging systems include fluorescent microscopes, optical microscopes, and telescopes. chemical imaging, the simultaneous measurement of spectra and pictures digital imaging, creating digital images, generally by scanning or through digital photography disk image, a file which contains the exact content of a data storage medium document imaging, replicating documents commonly is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemical the designing of transgenic plants to grow under specific environments in the presence ( or absence ) of chemicals. one hope is that green biotechnology might produce more environmentally friendly solutions than traditional industrial agriculture. an example of this is the engineering of a plant to express a pesticide, thereby ending the need of external application of pesticides. an example of this would be bt corn. whether or not green biotechnology products such as this are ultimately more environmentally friendly is a topic of considerable debate. it is commonly considered as the next phase of green revolution, which can be seen as a platform to eradicate world hunger by using technologies which enable the production of more fertile and resistant, towards biotic and abiotic stress, plants and ensures application of environmentally friendly fertilizers and the use of biopesticides, it is mainly focused on the development of agriculture. on the other hand, some of the uses of green biotechnology involve microorganisms to clean and reduce waste. red biotechnology is the use of biotechnology in the medical and pharmaceutical industries, and health preservation. this branch involves the production of vaccines and antibiotics, regenerative therapies, creation of artificial organs and new diagnostics of diseases. as well as the development of hormones, stem cells, antibodies, sirna and diagnostic tests. white biotechnology, also known as industrial biotechnology, is biotechnology applied to industrial processes. an example is the designing of an organism to produce a useful chemical. another example is the using of enzymes as industrial catalysts to either produce valuable chemicals or destroy hazardous / polluting chemicals. white biotechnology tends to consume less in resources than traditional processes used to produce industrial goods. yellow biotechnology refers to the use of biotechnology in food production ( food industry ), for example in making wine ( winemaking ), cheese ( cheesemaking ), and beer ( brewing ) by fermentation. it has also been used to refer to biotechnology applied to insects. this includes biotechnology - based approaches for the control of harmful insects, the characterisation and utilisation of active ingredients or genes of insects for research, or application in agriculture and medicine and various other approaches. gray biotechnology is dedicated to environmental applications, and focused on the maintenance of biodiversity and the remotion of pollutants. brown biotechnology is related to the management of arid lands and deserts. one application is the creation of enhanced seeds that resist extreme environmental conditions of arid regions, which is related to the innovation, creation of agriculture techniques and management of resources. violet biotechnology is related to law, ethical and philosophical issues around biotechnology. micro Question: What type of constraints are placed on technological design? A) legal and social B) physical and social C) moral and legal D) physical and legal	B) physical and social
Context: slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for gly . respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. the overall reaction occurs in a series of biochemical steps, some of which are redox reactions. although cellular respiration is technically a combustion reaction, it clearly does not resemble one when it occurs in a cell because of the slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycol = = = cellular respiration is a set of metabolic reactions and processes that take place in cells to convert chemical energy from nutrients into adenosine triphosphate ( atp ), and then release waste products. the reactions involved in respiration are catabolic reactions, which break large molecules into smaller ones, releasing energy. respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. the overall reaction occurs in a series of biochemical steps, some of which are redox reactions. although cellular respiration is technically a combustion reaction, it clearly does not resemble one when it occurs in a cell because of the slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes reaction to proceed more rapidly without being consumed by it — by reducing the amount of activation energy needed to convert reactants into products. enzymes also allow the regulation of the rate of a metabolic reaction, for example in response to changes in the cell ' s environment or to signals from other cells. = = = cellular respiration = = = cellular respiration is a set of metabolic reactions and processes that take place in cells to convert chemical energy from nutrients into adenosine triphosphate ( atp ), and then release waste products. the reactions involved in respiration are catabolic reactions, which break large molecules into smaller ones, releasing energy. respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. the overall reaction occurs in a series of biochemical steps, some of which are redox reactions. although cellular respiration is technically a combustion reaction, it clearly does not resemble one when it occurs in a cell because of the slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = meiosis is a central feature of sexual reproduction in eukaryotes, and the most fundamental function of meiosis appears to be conservation of the integrity of the genome that is passed on to progeny by parents. two aspects of sexual reproduction, meiotic recombination and outcrossing, are likely maintained respectively by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by Question: What cycle is the second stage of cellular respiration? A) electron transport chain B) sodium potassium pump C) glycolysis D) krebs cycle	D) krebs cycle
Context: not always mean it is required, especially when dealing with genetic or functional redundancy. tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. one way to do this is to replace the wild - type gene with a ' fusion ' gene, which is a juxtaposition of the wild - type gene with a reporting element such as green fluorescent protein ( gfp ) that will allow easy visualisation of the products of the genetic modification. while this is a useful technique, the manipulation can destroy the function of the gene, creating secondary effects and possibly calling into question the results of the experiment. more sophisticated techniques are now in development that can track protein products without mitigating their function, such as the addition of small sequences that will serve as binding motifs to monoclonal antibodies. expression studies aim to discover where and when specific proteins are produced. in these experiments, the dna sequence before the dna that codes for a protein, known as a gene ' s promoter, is reintroduced into an organism with the protein coding region replaced by a reporter gene such as gfp or an enzyme that catalyses the production of a dye. thus the time and place where a particular protein is produced can be observed. expression studies can be taken a step further by altering the promoter to find which pieces are crucial for the proper expression of the gene and are actually bound by transcription factor proteins ; this process is known as promoter bashing. = = = industrial = = = organisms can have their cells transformed with a gene coding for a useful protein, such as an enzyme, so that they will overexpress the desired protein. mass quantities of the protein can then be manufactured by growing the transformed organism in bioreactor equipment using industrial fermentation, and then purifying the protein. some genes do not work well in bacteria, so yeast, insect cells or mammalian cells can also be used. these techniques are used to produce medicines such as insulin, human growth hormone, and vaccines, supplements such as tryptophan, aid in the production of food ( chymosin in cheese making ) and fuels. other applications with genetically engineered bacteria could involve making them perform tasks outside their natural cycle, such as making biofuels, cleaning up oil spills, carbon and other toxic waste and detecting arsenic in drinking water. certain genetically modified microbes can also be used in biomining and bioremediation, due to their ability to extract heavy metals from their environment and incorporate them into compounds that are more easily recover conditions of early earth, thus suggesting that complex organic molecules could have arisen spontaneously in early earth ( see abiogenesis ). = = = macromolecules = = = macromolecules are large molecules made up of smaller subunits or monomers. monomers include sugars, amino acids, and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids are polymers of nucleotides. their function is to store, transmit, and express hereditary information. = = cells = = cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, and that all cells arise from preexisting cells through cell division. most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes process by which a genotype encoded in dna gives rise to an observable phenotype in the proteins of an organism ' s body. this process is summarized by the central dogma of molecular biology, which was formulated by francis crick in 1958. according to the central dogma, genetic information flows from dna to rna to protein. there are two gene expression processes : transcription ( dna to rna ) and translation ( rna to protein ). = = = gene regulation = = = the regulation of gene expression by environmental factors and during different stages of development can occur at each step of the process such as transcription, rna splicing, translation, and post - translational modification of a protein. gene expression can be influenced by positive or negative regulation, depending on which of the two types of regulatory proteins called transcription factors bind to the dna sequence close to or at a promoter. a cluster of genes that share the same promoter is called an operon, found mainly in prokaryotes and some lower eukaryotes ( e. g., caenorhabditis elegans ). in positive regulation of gene expression, the activator is the transcription factor that stimulates transcription when it binds to the sequence near or at the promoter. negative regulation occurs when another transcription factor called a repressor binds to a dna sequence called an operator, which is part of an operon, to prevent transcription. repressors can be inhibited by compounds called inducers ( e. g., allolactose ), thereby allowing transcription to occur. specific genes that can be activated by inducers are called inducible genes, in contrast to constitutive genes that are almost constantly active. in contrast to both, structural genes encode proteins that are not involved in gene regulation. in addition to regulatory events involving the promoter, gene expression can also be regulated by epigenetic changes to chromatin, which is a complex of dna and protein found in eukaryotic cells. = = = genes, development, and evolution = = = development is the process by which a multicellular organism ( plant or animal ) goes through a series of changes, starting from a single cell, and taking on various forms that are characteristic of its life cycle. there are four key processes that underlie development : determination, differentiation, morphogenesis, and growth. determination sets the developmental fate of a cell, which becomes more restrictive during development. differentiation is the process by which specialized cells arise from less specialized cells such as stem water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids are polymers of nucleotides. their function is to store, transmit, and express hereditary information. = = cells = = cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, and that all cells arise from preexisting cells through cell division. most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell, there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of a binary 1 - error - correcting code can always be embedded in a 1 - perfect code of some larger length usability engineering, it ' s important target and identify human errors when interacting with the product of interest because if a user is expected to engage with a product, interface, or service in some way, the very introduction of a human in that engagement increases the potential of encountering human error. error should be reduced as much as possible in order to avoid frustration or injury. there are two main types of human errors which are categorized as slips and mistakes. slips are a very common kind of error involving automatic behaviors ( i. e. typos, hitting the wrong menu item ). when we experience slips, we have the correct goal in mind, but execute the wrong action. mistakes on the other hand involve conscious deliberation that result in the incorrect conclusion. when we experience mistakes, we have the wrong goal in mind and thereby execute the wrong action. even though slips are the more common type of error, they are no less dangerous. a certain type of slip error, a mode error, can be especially dangerous if a user is executing a high - risk task. for instance, if a user is operating a vehicle and does not realize they are in the wrong mode ( i. e. reverse ), they might step on the gas intending to drive, but instead accelerate into a garage wall or another car. in order to avoid modal errors, designers often employ modeless states in which users do not have to choose a mode at all, or they must execute a continuous action while intending to execute a certain mode ( i. e. pressing a key continuously in order to activate " lasso " mode in photoshop ). = = evaluation methods = = usability engineers conduct usability evaluations of existing or proposed interfaces and their findings are fed back to the designer for use in design or redesign. common usability evaluation methods include : card sorting cognitive task analysis cognitive walkthroughs contextual inquiry focus groups heuristic evaluations interviews questionnaires rite method surveys think aloud protocol usability testing = = software applications and development tools = = there are a variety of online resources that make the job of a usability engineer a little easier. online tools are only a useful tool, and do not substitute for a complete usability engineering analysis. some examples of these include : = = = the web metrics tool suite = = = this is a product of the national institute of standards and technology. this toolkit is focused on evaluating the html of a website versus a wide range of usability guidelines and includes : web static analyzer tool genetic engineering takes the gene directly from one organism and delivers it to the other. this is much faster, can be used to insert any genes from any organism ( even ones from different domains ) and prevents other undesirable genes from also being added. genetic engineering could potentially fix severe genetic disorders in humans by replacing the defective gene with a functioning one. it is an important tool in research that allows the function of specific genes to be studied. drugs, vaccines and other products have been harvested from organisms engineered to produce them. crops have been developed that aid food security by increasing yield, nutritional value and tolerance to environmental stresses. the dna can be introduced directly into the host organism or into a cell that is then fused or hybridised with the host. this relies on recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro - injection, macro - injection or micro - encapsulation. genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. however, some broad definitions of genetic engineering include selective breeding. cloning and stem cell research, although not considered genetic engineering, are closely related and genetic engineering can be used within them. synthetic biology is an emerging discipline that takes genetic engineering a step further by introducing artificially synthesised material into an organism. plants, animals or microorganisms that have been changed through genetic engineering are termed genetically modified organisms or gmos. if genetic material from another species is added to the host, the resulting organism is called transgenic. if genetic material from the same species or a species that can naturally breed with the host is used the resulting organism is called cisgenic. if genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a knockout organism. in europe genetic modification is synonymous with genetic engineering while within the united states of america and canada genetic modification can also be used to refer to more conventional breeding methods. = = history = = humans have altered the genomes of species for thousands of years through selective breeding, or artificial selection : 1 : 1 as contrasted with natural selection. more recently, mutation breeding has used exposure to chemicals or radiation to produce a high frequency of random mutations, for selective breeding purposes. genetic engineering as the direct manipulation of dna by humans outside breeding and ##ally, because the natural shapes of crystals reflect the atomic structure. further, physical properties are often controlled by crystalline defects. the understanding of crystal structures is an important prerequisite for understanding crystallographic defects. examples of crystal defects consist of dislocations including edges, screws, vacancies, self inter - stitials, and more that are linear, planar, and three dimensional types of defects. new and advanced materials that are being developed include nanomaterials, biomaterials. mostly, materials do not occur as a single crystal, but in polycrystalline form, as an aggregate of small crystals or grains with different orientations. because of this, the powder diffraction method, which uses diffraction patterns of polycrystalline samples with a large number of crystals, plays an important role in structural determination. most materials have a crystalline structure, but some important materials do not exhibit regular crystal structure. polymers display varying degrees of crystallinity, and many are completely non - crystalline. glass, some ceramics, and many natural materials are amorphous, not possessing any long - range order in their atomic arrangements. the study of polymers combines elements of chemical and statistical thermodynamics to give thermodynamic and mechanical descriptions of physical properties. = = = = nanostructure = = = = materials, which atoms and molecules form constituents in the nanoscale ( i. e., they form nanostructures ) are called nanomaterials. nanomaterials are the subject of intense research in the materials science community due to the unique properties that they exhibit. nanostructure deals with objects and structures that are in the 1 – 100 nm range. in many materials, atoms or molecules agglomerate to form objects at the nanoscale. this causes many interesting electrical, magnetic, optical, and mechanical properties. in describing nanostructures, it is necessary to differentiate between the number of dimensions on the nanoscale. nanotextured surfaces have one dimension on the nanoscale, i. e., only the thickness of the surface of an object is between 0. 1 and 100 nm. nanotubes have two dimensions on the nanoscale, i. e., the diameter of the tube is between 0. 1 and 100 nm ; its length could be much greater. finally, spherical nanoparticles have three dimensions on the nanoscale, i. e., the particle is between to that of a flat crack through the plain matrix. the magnitude of the toughening is determined by the mismatch strain caused by thermal contraction incompatibility and the microfracture resistance of the particle / matrix interface. the toughening becomes noticeable with a narrow size distribution of appropriately sized particles, and researchers typically accept that deflection effects in materials with roughly equiaxial grains may increase the fracture toughness by about twice the grain boundary value. the model reveals that the increase in toughness is dependent on particle shape and the volume fraction of the second phase, with the most effective morphology being the rod of high aspect ratio, which can account for a fourfold increase in fracture toughness. the toughening arises primarily from the twist of the crack front between particles, as indicated by deflection profiles. disc - shaped particles and spheres are less effective in toughening. fracture toughness, regardless of morphology, is determined by the twist of the crack front at its most severe configuration, rather than the initial tilt of the crack front. only for disc - shaped particles does the initial tilting of the crack front provide significant toughening ; however, the twist component still overrides the tilt - derived toughening. additional important features of the deflection analysis include the appearance of asymptotic toughening for the three morphologies at volume fractions in excess of 0. 2. it is also noted that a significant influence on the toughening by spherical particles is exerted by the interparticle spacing distribution ; greater toughening is afforded when spheres are nearly contacting such that twist angles approach π / 2. these predictions provide the basis for the design of high - toughness two - phase ceramic materials. the ideal second phase, in addition to maintaining chemical compatibility, should be present in amounts of 10 to 20 volume percent. greater amounts may diminish the toughness increase due to overlapping particles. particles with high aspect ratios, especially those with rod - shaped morphologies, are most suitable for maximum toughening. this model is often used to determine the factors that contribute to the increase in fracture toughness in ceramics which is ultimately useful in the development of advanced ceramic materials with improved performance. = = theory of chemical processing = = = = = microstructural uniformity = = = in the processing of fine ceramics, the irregular particle sizes and shapes in a typical powder often lead to non - uniform packing morphologies that result in packing density variations in the powder compact. uncontrolled aggl erroneous submission in violation of copyright removed by arxiv admin. Question: What phenomenon can cause a protein in an organism to be made incorrectly? A) allele B) mutation C) evolution D) heredity	B) mutation
Context: wave, carrying an information signal, occupies a range of frequencies. the information in a radio signal is usually concentrated in narrow frequency bands called sidebands ( sb ) just above and below the carrier frequency. the width in hertz of the frequency range that the radio signal occupies, the highest frequency minus the lowest frequency, is called its bandwidth ( bw ). for any given signal - to - noise ratio, a given bandwidth can carry the same amount of information regardless of where in the radio frequency spectrum it is located ; bandwidth is a measure of information - carrying capacity. the bandwidth required by a radio transmission depends on the data rate of the information being sent, and the spectral efficiency of the modulation method used ; how much data it can transmit in each unit of bandwidth. different types of information signals carried by radio have different data rates. for example, a television signal has a greater data rate than an audio signal. the radio spectrum, the total range of radio frequencies that can be used for communication in a given area, is a limited resource. each radio transmission occupies a portion of the total bandwidth available. radio bandwidth is regarded as an economic good which has a monetary cost and is in increasing demand. in some parts of the radio spectrum, the right to use a frequency band or even a single radio channel is bought and sold for millions of dollars. so there is an incentive to employ technology to minimize the bandwidth used by radio services. a slow transition from analog to digital radio transmission technologies began in the late 1990s. part of the reason for this is that digital modulation can often transmit more information ( a greater data rate ) in a given bandwidth than analog modulation, by using data compression algorithms, which reduce redundancy in the data to be sent, and more efficient modulation. other reasons for the transition is that digital modulation has greater noise immunity than analog, digital signal processing chips have more power and flexibility than analog circuits, and a wide variety of types of information can be transmitted using the same digital modulation. because it is a fixed resource which is in demand by an increasing number of users, the radio spectrum has become increasingly congested in recent decades, and the need to use it more effectively is driving many additional radio innovations such as trunked radio systems, spread spectrum ( ultra - wideband ) transmission, frequency reuse, dynamic spectrum management, frequency pooling, and cognitive radio. = = = itu frequency bands = = = the itu arbitrarily divides the radio spectrum into 12 bands, each beginning at a wavelength which is a power electromagnetic induction. the transmission speed ranges from 2 mbit / s to 10 gbit / s. twisted pair cabling comes in two forms : unshielded twisted pair ( utp ) and shielded twisted - pair ( stp ). each form comes in several category ratings, designed for use in various scenarios. an optical fiber is a glass fiber. it carries pulses of light that represent data via lasers and optical amplifiers. some advantages of optical fibers over metal wires are very low transmission loss and immunity to electrical interference. using dense wave division multiplexing, optical fibers can simultaneously carry multiple streams of data on different wavelengths of light, which greatly increases the rate that data can be sent to up to trillions of bits per second. optic fibers can be used for long runs of cable carrying very high data rates, and are used for undersea communications cables to interconnect continents. there are two basic types of fiber optics, single - mode optical fiber ( smf ) and multi - mode optical fiber ( mmf ). single - mode fiber has the advantage of being able to sustain a coherent signal for dozens or even a hundred kilometers. multimode fiber is cheaper to terminate but is limited to a few hundred or even only a few dozens of meters, depending on the data rate and cable grade. = = = wireless = = = network connections can be established wirelessly using radio or other electromagnetic means of communication. terrestrial microwave – terrestrial microwave communication uses earth - based transmitters and receivers resembling satellite dishes. terrestrial microwaves are in the low gigahertz range, which limits all communications to line - of - sight. relay stations are spaced approximately 40 miles ( 64 km ) apart. communications satellites – satellites also communicate via microwave. the satellites are stationed in space, typically in geosynchronous orbit 35, 400 km ( 22, 000 mi ) above the equator. these earth - orbiting systems are capable of receiving and relaying voice, data, and tv signals. cellular networks use several radio communications technologies. the systems divide the region covered into multiple geographic areas. each area is served by a low - power transceiver. radio and spread spectrum technologies – wireless lans use a high - frequency radio technology similar to digital cellular. wireless lans use spread spectrum technology to enable communication between multiple devices in a limited area. ieee 802. 11 defines a common flavor of open - standards wireless radio - wave technology known as wi - fi. free - space optical communication uses visible or invisible light for communications. in most cases, line - of generation of direct current in zigzag carbon nanotubes due to harmonic mixing of two coherent electromagnetic waves is being considered. the electromagnetic waves have commensurate frequencies of omega and two omega. the rectification of the waves at high frequencies is quite smooth whiles at low frequencies there are some fluctuations. the nonohmicity observed in the i - vcharacteristics is attributed to the nonparabolicity of the electron energy band which is very strong in carbon nanotubes because of high stark component. it is observed that the current falls off faster at lower electric field than the case in superlattice. for omega tau equal to two? the external electric field strength emax for the observation of negative differential conductivity occurs around 1. 03x10e6 v / m which is quite weak. it is interesting to note that the peak of the curve shifts to the left with increasing value of omega tau? the dynamic impedance of a sphere oscillating in an elastic medium is considered. oestreicher ' s formula for the impedance of a sphere bonded to the surrounding medium can be expressed simply in terms of three lumped impedances associated with the displaced mass and the longitudinal and transverse waves. if the surface of the sphere slips while the normal velocity remains continuous, the impedance formula is modified by adjusting the definition of the transverse impedance to include the interfacial impedance. stations located in places like light poles or building roofs. in the past, 4g networking had to rely on large cell towers in order to transmit signals over large distances. with the introduction of 5g networking, it is imperative that small cell stations are used because the mm wave spectrum, which is the specific type of band used in 5g services, strictly travels over short distances. if the distances between cell stations were longer, signals may suffer from interference from inclimate weather, or other objects such as houses, buildings, trees, and much more. in 5g networking, there are 3 main kinds of 5g : low - band, mid - band, and high - band. low - band frequencies operate below 2 ghz, mid - band frequencies operate between 2 – 10 ghz, and high - band frequencies operate between 20 and 100 ghz. verizon have seen outrageous numbers on their high - band 5g service, which they deem " ultraband ", which hit speeds of over 3 gbit / s. the main advantage of 5g networks is that the data transmission rate is much higher than the previous cellular network, up to 10 gbit / s, which is faster than the current wired internet and 100 times faster than the previous 4g lte cellular network. another advantage is lower network latency ( faster response time ), less than 1 millisecond, and 4g is 30 - 70 milliseconds. the peak rate needs to reach the gbit / s standard to meet the high data volume of high - definition video, virtual reality and so on. the air interface delay level needs to be around 1ms, which meets real - time applications such as autonomous driving and telemedicine. large network capacity, providing the connection capacity of 100 billion devices to meet iot communication. the spectrum efficiency is 10 times higher than lte. with continuous wide area coverage and high mobility, the user experience rate reaches 100 mbit / s. the flow density and the number of connections are greatly increased. since 5g is a relatively new type of service, only phones which are newly released or are upcoming can support 5g service. some of these phones include the iphone 12 / 13 ; select samsung devices such as the s21 series, note series, flip / fold series, a series ; google pixel 4a / 5 ; and a few more devices from other manufacturers. the first ever 5g smartphone, the samsung galaxy s20, was released by samsung in march 2020. following the release of samsung ' s s missiles, ships, vehicles, and also to map weather patterns and terrain. a radar set consists of a transmitter and receiver. the transmitter emits a narrow beam of radio waves which is swept around the surrounding space. when the beam strikes a target object, radio waves are reflected back to the receiver. the direction of the beam reveals the object ' s location. since radio waves travel at a constant speed close to the speed of light, by measuring the brief time delay between the outgoing pulse and the received " echo ", the range to the target can be calculated. the targets are often displayed graphically on a map display called a radar screen. doppler radar can measure a moving object ' s velocity, by measuring the change in frequency of the return radio waves due to the doppler effect. radar sets mainly use high frequencies in the microwave bands, because these frequencies create strong reflections from objects the size of vehicles and can be focused into narrow beams with compact antennas. parabolic ( dish ) antennas are widely used. in most radars the transmitting antenna also serves as the receiving antenna ; this is called a monostatic radar. a radar which uses separate transmitting and receiving antennas is called a bistatic radar. airport surveillance radar – in aviation, radar is the main tool of air traffic control. a rotating dish antenna sweeps a vertical fan - shaped beam of microwaves around the airspace and the radar set shows the location of aircraft as " blips " of light on a display called a radar screen. airport radar operates at 2. 7 – 2. 9 ghz in the microwave s band. in large airports the radar image is displayed on multiple screens in an operations room called the tracon ( terminal radar approach control ), where air traffic controllers direct the aircraft by radio to maintain safe aircraft separation. secondary surveillance radar – aircraft carry radar transponders, transceivers which when triggered by the incoming radar signal transmit a return microwave signal. this causes the aircraft to show up more strongly on the radar screen. the radar which triggers the transponder and receives the return beam, usually mounted on top of the primary radar dish, is called the secondary surveillance radar. since radar cannot measure an aircraft ' s altitude with any accuracy, the transponder also transmits back the aircraft ' s altitude measured by its altimeter, and an id number identifying the aircraft, which is displayed on the radar screen. electronic countermeasures ( ecm ) – military defensive electronic systems designed to degrade enemy radar effectiveness, or deceive it the higher microwave band 3 – 6 ghz, and millimeter wave band, around 28 and 39 ghz. since these frequencies have a shorter range than previous cellphone bands, the cells will be smaller than the cells in previous cellular networks which could be many miles across. millimeter - wave cells will only be a few blocks long, and instead of a cell base station and antenna tower, they will have many small antennas attached to utility poles and buildings. satellite phone ( satphone ) – a portable wireless telephone similar to a cell phone, connected to the telephone network through a radio link to an orbiting communications satellite instead of through cell towers. they are more expensive than cell phones ; but their advantage is that, unlike a cell phone which is limited to areas covered by cell towers, satphones can be used over most or all of the geographical area of the earth. in order for the phone to communicate with a satellite using a small omnidirectional antenna, first - generation systems use satellites in low earth orbit, about 400 – 700 miles ( 640 – 1, 100 km ) above the surface. with an orbital period of about 100 minutes, a satellite can only be in view of a phone for about 4 – 15 minutes, so the call is " handed off " to another satellite when one passes beyond the local horizon. therefore, large numbers of satellites, about 40 to 70, are required to ensure that at least one satellite is in view continuously from each point on earth. other satphone systems use satellites in geostationary orbit in which only a few satellites are needed, but these cannot be used at high latitudes because of terrestrial interference. cordless phone – a landline telephone in which the handset is portable and communicates with the rest of the phone by a short - range full duplex radio link, instead of being attached by a cord. both the handset and the base station have low - power radio transceivers that handle the short - range bidirectional radio link. as of 2022, cordless phones in most nations use the dect transmission standard. land mobile radio system – short - range mobile or portable half - duplex radio transceivers operating in the vhf or uhf band that can be used without a license. they are often installed in vehicles, with the mobile units communicating with a dispatcher at a fixed base station. special systems with reserved frequencies are used by first responder services ; police, fire, ambulance, and emergency services, and other government services. other systems are made for electromagnetic soliton - particle with both quasi - static and quick - oscillating wave parts is considered. its mass, spin, charge, and magnetic moment appear naturally when the interaction with distant solitons is considered. the substantiation of dirac equation for the wave part of the interacting soliton - particle is given. rolling out 5g services across the us. 5g started being deployed at the beginning of 2020 and has been growing ever since. according to the gsm association, by 2025, approximately 1. 7 billion subscribers will have a subscription with 5g service. 5g wireless signals are transmitted through large numbers of small cell stations located in places like light poles or building roofs. in the past, 4g networking had to rely on large cell towers in order to transmit signals over large distances. with the introduction of 5g networking, it is imperative that small cell stations are used because the mm wave spectrum, which is the specific type of band used in 5g services, strictly travels over short distances. if the distances between cell stations were longer, signals may suffer from interference from inclimate weather, or other objects such as houses, buildings, trees, and much more. in 5g networking, there are 3 main kinds of 5g : low - band, mid - band, and high - band. low - band frequencies operate below 2 ghz, mid - band frequencies operate between 2 – 10 ghz, and high - band frequencies operate between 20 and 100 ghz. verizon have seen outrageous numbers on their high - band 5g service, which they deem " ultraband ", which hit speeds of over 3 gbit / s. the main advantage of 5g networks is that the data transmission rate is much higher than the previous cellular network, up to 10 gbit / s, which is faster than the current wired internet and 100 times faster than the previous 4g lte cellular network. another advantage is lower network latency ( faster response time ), less than 1 millisecond, and 4g is 30 - 70 milliseconds. the peak rate needs to reach the gbit / s standard to meet the high data volume of high - definition video, virtual reality and so on. the air interface delay level needs to be around 1ms, which meets real - time applications such as autonomous driving and telemedicine. large network capacity, providing the connection capacity of 100 billion devices to meet iot communication. the spectrum efficiency is 10 times higher than lte. with continuous wide area coverage and high mobility, the user experience rate reaches 100 mbit / s. the flow density and the number of connections are greatly increased. since 5g is a relatively new type of service, only phones which are newly released or are upcoming can support 5g service. some of these phones include the iphone 12 / 13 ; select wireless communication ( or just wireless, when the context allows ) is the transfer of information ( telecommunication ) between two or more points without the use of an electrical conductor, optical fiber or other continuous guided medium for the transfer. the most common wireless technologies use radio waves. with radio waves, intended distances can be short, such as a few meters for bluetooth, or as far as millions of kilometers for deep - space radio communications. it encompasses various types of fixed, mobile, and portable applications, including two - way radios, cellular telephones, personal digital assistants ( pdas ), and wireless networking. other examples of applications of radio wireless technology include gps units, garage door openers, wireless computer mouse, keyboards and headsets, headphones, radio receivers, satellite television, broadcast television and cordless telephones. somewhat less common methods of achieving wireless communications involve other electromagnetic phenomena, such as light and magnetic or electric fields, or the use of sound. the term wireless has been used twice in communications history, with slightly different meanings. it was initially used from about 1890 for the first radio transmitting and receiving technology, as in wireless telegraphy, until the new word radio replaced it around 1920. radio sets in the uk and the english - speaking world that were not portable continued to be referred to as wireless sets into the 1960s. the term wireless was revived in the 1980s and 1990s mainly to distinguish digital devices that communicate without wires, such as the examples listed in the previous paragraph, from those that require wires or cables. this became its primary usage in the 2000s, due to the advent of technologies such as mobile broadband, wi - fi, and bluetooth. wireless operations permit services, such as mobile and interplanetary communications, that are impossible or impractical to implement with the use of wires. the term is commonly used in the telecommunications industry to refer to telecommunications systems ( e. g. radio transmitters and receivers, remote controls, etc. ) that use some form of energy ( e. g. radio waves and acoustic energy ) to transfer information without the use of wires. information is transferred in this manner over both short and long distances. = = history = = = = = photophone = = = the first wireless telephone conversation occurred in 1880 when alexander graham bell and charles sumner tainter invented the photophone, a telephone that sent audio over a beam of light. the photophone required sunlight to operate, and a clear line of sight between the transmitter and receiver, which greatly decreased the viability of the photophone in any practical use Question: What are mid-wavelength electromagnetic waves commonly referred to as? A) x-rays B) electricity C) gamma rays D) light	D) light
Context: the clinical symptoms of pulmonary embolism ( pe ) are very diverse and non - specific, which makes it difficult to diagnose. in addition, pulmonary embolism has multiple triggers and is one of the major causes of vascular death. therefore, if it can be detected and treated quickly, it can significantly reduce the risk of death in hospitalized patients. in the detection process, the cost of computed tomography pulmonary angiography ( ctpa ) is high, and angiography requires the injection of contrast agents, which increase the risk of damage to the patient. therefore, this study will use a deep learning approach to detect pulmonary embolism in all patients who take a ct image of the chest using a convolutional neural network. with the proposed pulmonary embolism detection system, we can detect the possibility of pulmonary embolism at the same time as the patient ' s first ct image, and schedule the ctpa test immediately, saving more than a week of ct image screening time and providing timely diagnosis and treatment to the patient. muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up the muck tube. the pressurized air flow must be constant to ensure regular air changes for the workers and prevent excessive inflow of mud or water at the base of the caisson. when the caisson hits bedrock, the sandhogs exit through the airlock and fill the box with concrete, forming a solid foundation pier. a pneumatic ( compressed - air ) caisson has the advantage of providing dry working conditions, which is better for placing concrete. it is also well suited for foundations for which other methods might cause settlement of adjacent structures. construction workers who leave the pressurized environment of the caisson must decompress at a rate that allows symptom - free release of inert gases dissolved in the body tissues if they are to avoid decompression sickness, a condition first identified in caisson workers, and originally named " caisson disease " in recognition of the occupational hazard. construction of the brooklyn bridge, which was built with the help of pressurised caissons, resulted in numerous workers being either killed or permanently injured by caisson disease during its construction. barotrauma of the ears, sinus cavities and lungs and dysbaric osteonecrosis are other risks. = = other uses = = caissons have also been used in the installation of hydraulic elevators where a single - stage ram is installed below the ground level. caissons, codenamed phoenix, were an integral part of the mulberry harbours used during the world war ii allied invasion of normandy. = = other meanings = = boat lift caissons : the word caisson is also used as a synonym for the moving trough part of caisson locks, canal lifts and inclines in which boats and ships rest while being lifted from one canal elevation to another ; the water is retained on the inside of the caisson, or excluded from the caisson, according to the respective operating principle. structural caissons : caisson is also sometimes used as a colloquial term for a reinforced concrete structure formed by pouring into a hollow cylindrical form, typically by placing a caisson form below grade in an open excavation and pouring once backfill is complete, or by fluid dynamics video demonstrating the evolution of dynamic stall on a wind turbine blade. comment on " event excess in the miniboone search for $ \ bar \ nu _ { \ mu } \ rightarrow \ bar \ nu _ e $ oscillations " the following purposes : allowing cell attachment and migration, delivering and retaining cells and biochemical factors, enabling diffusion of vital cell nutrients and expressed products, and exerting certain mechanical and biological influences to modify the behaviour of the cell phase. in 2009, an interdisciplinary team led by the thoracic surgeon thorsten walles implanted the first bioartificial transplant that provides an innate vascular network for post - transplant graft supply successfully into a patient awaiting tracheal reconstruction. to achieve the goal of tissue reconstruction, scaffolds must meet some specific requirements. high porosity and adequate pore size are necessary to facilitate cell seeding and diffusion throughout the whole structure of both cells and nutrients. biodegradability is often an essential factor since scaffolds should preferably be absorbed by the surrounding tissues without the necessity of surgical removal. the rate at which degradation occurs has to coincide as much as possible with the rate of tissue formation : this means that while cells are fabricating their own natural matrix structure around themselves, the scaffold is able to provide structural integrity within the body and eventually it will break down leaving the newly formed tissue which will take over the mechanical load. injectability is also important for clinical uses. recent research on organ printing is showing how crucial a good control of the 3d environment is to ensure reproducibility of experiments and offer better results. = = = materials = = = material selection is an essential aspect of producing a scaffold. the materials utilized can be natural or synthetic and can be biodegradable or non - biodegradable. additionally, they must be biocompatible, meaning that they do not cause any adverse effects to cells. silicone, for example, is a synthetic, non - biodegradable material commonly used as a drug delivery material, while gelatin is a biodegradable, natural material commonly used in cell - culture scaffolds the material needed for each application is different, and dependent on the desired mechanical properties of the material. tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone ( 100 - 150 mpa ), which is much higher compared to a scaffold for skin regeneration. there are a few versatile synthetic materials used for many different scaffold applications. one of these commonly used materials is polylactic acid ( pla ), a synthetic polymer. pla – polylactic acid. this is a polyester which medical purposes. cells are often ' seeded ' into these structures capable of supporting three - dimensional tissue formation. scaffolds mimic the extracellular matrix of the native tissue, recapitulating the in vivo milieu and allowing cells to influence their own microenvironments. they usually serve at least one of the following purposes : allowing cell attachment and migration, delivering and retaining cells and biochemical factors, enabling diffusion of vital cell nutrients and expressed products, and exerting certain mechanical and biological influences to modify the behaviour of the cell phase. in 2009, an interdisciplinary team led by the thoracic surgeon thorsten walles implanted the first bioartificial transplant that provides an innate vascular network for post - transplant graft supply successfully into a patient awaiting tracheal reconstruction. to achieve the goal of tissue reconstruction, scaffolds must meet some specific requirements. high porosity and adequate pore size are necessary to facilitate cell seeding and diffusion throughout the whole structure of both cells and nutrients. biodegradability is often an essential factor since scaffolds should preferably be absorbed by the surrounding tissues without the necessity of surgical removal. the rate at which degradation occurs has to coincide as much as possible with the rate of tissue formation : this means that while cells are fabricating their own natural matrix structure around themselves, the scaffold is able to provide structural integrity within the body and eventually it will break down leaving the newly formed tissue which will take over the mechanical load. injectability is also important for clinical uses. recent research on organ printing is showing how crucial a good control of the 3d environment is to ensure reproducibility of experiments and offer better results. = = = materials = = = material selection is an essential aspect of producing a scaffold. the materials utilized can be natural or synthetic and can be biodegradable or non - biodegradable. additionally, they must be biocompatible, meaning that they do not cause any adverse effects to cells. silicone, for example, is a synthetic, non - biodegradable material commonly used as a drug delivery material, while gelatin is a biodegradable, natural material commonly used in cell - culture scaffolds the material needed for each application is different, and dependent on the desired mechanical properties of the material. tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone ( 100 - 150 mpa ), listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, christian emphasis on practical charity gave rise to the development of systematic nursing and hospitals, and the catholic church today remains the largest non - government provider of medical services in the world. advanced industrial countries ( with the exception of the united states ) and many developing countries provide medical services through a system of universal health care that aims to classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filtration behavior and selectivity. the selectivity is highly dependent on the separation process, the composition of the membrane and its electrochemical properties in addition to the pore size. with high selectivity, isotopes can be enriched ( uranium enrichment ) in nuclear engineering or industrial gases like nitrogen can be recovered ( gas separation ). ideally, even racemics can be enriched with a suitable membrane. when choosing membranes selectivity has priority over a high permeability, as low flows can easily be offset by increasing the filter surface with a modular structure. in gas phase filtration different deposition mechanisms are operative, so that particles having sizes below the pore size of the membrane can be retained as well. = = membrane classification = = bio - membrane is classified in two categories, synthetic membrane and natural membrane. synthetic membranes further classified in organic and inorganic membranes. organic membrane sub classified polymeric membranes and inorganic membrane sub classified ceramic polymers. = = synthesis of biomass membrane development and interaction of starting vortices initiated by dielectric barrier discharge ( dbd ) plasma actuators in quiescent air are illustrated in the attached fluid dynamics videos. these include a series of smoke flow visualisations, showing the starting vortices moving parallel or normal to the wall at several different actuator configurations. see q - alg / 9710003 for the corrected version of this paper. Question: Bronchial tubes in the lungs branch into ever-smaller structures, finally ending in alveoli. the alveoli act like what? A) filters B) tiny bubbles C) springs D) bellows	B) tiny bubbles
Context: a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be classified as an acid or a base. there are several different theories which explain acid – base behavior. the simplest is arrhenius theory, which states that an acid is a substance that produces hydronium ions when it is dissolved in water, and a base is one that produces hydroxide ions when dissolved in water. . oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants. a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer reaction to proceed more rapidly without being consumed by it — by reducing the amount of activation energy needed to convert reactants into products. enzymes also allow the regulation of the rate of a metabolic reaction, for example in response to changes in the cell ' s environment or to signals from other cells. = = = cellular respiration = = = cellular respiration is a set of metabolic reactions and processes that take place in cells to convert chemical energy from nutrients into adenosine triphosphate ( atp ), and then release waste products. the reactions involved in respiration are catabolic reactions, which break large molecules into smaller ones, releasing energy. respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. the overall reaction occurs in a series of biochemical steps, some of which are redox reactions. although cellular respiration is technically a combustion reaction, it clearly does not resemble one when it occurs in a cell because of the slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle ), electron transport chain, and oxidative phosphorylation. glycolysis is a metabolic process that occurs in the cytoplasm whereby glucose is converted into two pyruvates, with two net molecules of atp being produced at the same time. each pyruvate is then oxidized into acetyl - coa by the pyruvate dehydrogenase complex, which also generates nadh and carbon dioxide. acetyl - coa enters the citric acid cycle, which takes places inside the mitochondrial matrix. at the end of the cycle, the total yield from 1 glucose ( or 2 pyruvates ) is 6 nadh, 2 fadh2, and 2 atp molecules. finally, the next stage is oxidative phosphorylation, which in eukaryotes, occurs in the mitochondrial cristae. oxidative phosphorylation comprises the electron transport chain, which is a series of four protein complexes that transfer electrons from one complex to another, thereby releasing energy from nadh and fadh2 that is coupled to the pumping of protons ( hydrogen ions ) across the inner mitochondrial membrane ( chemiosmosis ), which generates a proton motive force. energy with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by . a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of delay of ripening, increase of juice yield, and improvement of re - hydration. irradiation is a more general term of deliberate exposure of materials to radiation to achieve a technical goal ( in this context ' ionizing radiation ' is implied ). as such it is also used on non - food items, such as medical hardware, plastics, tubes for gas - pipelines, hoses for floor - heating, shrink - foils for food packaging, automobile parts, wires and cables ( isolation ), tires, and even gemstones. compared to the amount of food irradiated, the volume of those every - day applications is huge but not noticed by the consumer. the genuine effect of processing food by ionizing radiation relates to damages to the dna, the basic genetic information for life. microorganisms can no longer proliferate and continue their malignant or pathogenic activities. spoilage causing micro - organisms cannot continue their activities. insects do not survive or become incapable of procreation. plants cannot continue the natural ripening or aging process. all these effects are beneficial to the consumer and the food industry, likewise. the amount of energy imparted for effective food irradiation is low compared to cooking the same ; even at a typical dose of 10 kgy most food, which is ( with regard to warming ) physically equivalent to water, would warm by only about 2. 5 °c ( 4. 5 °f ). the specialty of processing food by ionizing radiation is the fact, that the energy density per atomic transition is very high, it can cleave molecules and induce ionization ( hence the name ) which cannot be achieved by mere heating. this is the reason for new beneficial effects, however at the same time, for new concerns. the treatment of solid food by ionizing radiation can provide an effect similar to heat pasteurization of liquids, such as milk. however, the use of the term, cold pasteurization, to describe irradiated foods is controversial, because pasteurization and irradiation are fundamentally different processes, although the intended end results can in some cases be similar. detractors of food irradiation have concerns about the health hazards of induced radioactivity. a report for the industry advocacy group american council on science and health entitled " irradiated foods " states : " the types of radiation sources approved for the treatment of foods have specific energy levels well below that which would cause any element in food to become radioactive. food undergoing irradiation does not become any more Question: What can be used to accelerate the rate at which chemical reactions occur? A) components B) protein C) enzymes D) hormones	C) enzymes
Context: higher concentrations of atmospheric nitrous oxide ( n2o ) are expected to slightly warm earth ' s surface because of increases in radiative forcing. radiative forcing is the difference in the net upward thermal radiation flux from the earth through a transparent atmosphere and radiation through an otherwise identical atmosphere with greenhouse gases. radiative forcing, normally measured in w / m ^ 2, depends on latitude, longitude and altitude, but it is often quoted for the tropopause, about 11 km of altitude for temperate latitudes, or for the top of the atmosphere at around 90 km. for current concentrations of greenhouse gases, the radiative forcing per added n2o molecule is about 230 times larger than the forcing per added carbon dioxide ( co2 ) molecule. this is due to the heavy saturation of the absorption band of the relatively abundant greenhouse gas, co2, compared to the much smaller saturation of the absorption bands of the trace greenhouse gas n2o. but the rate of increase of co2 molecules, about 2. 5 ppm / year ( ppm = part per million by mole ), is about 3000 times larger than the rate of increase of n2o molecules, which has held steady at around 0. 00085 ppm / year since 1985. so, the contribution of nitrous oxide to the annual increase in forcing is 230 / 3000 or about 1 / 13 that of co2. if the main greenhouse gases, co2, ch4 and n2o have contributed about 0. 1 c / decade of the warming observed over the past few decades, this would correspond to about 0. 00064 k per year or 0. 064 k per century of warming from n2o. proposals to place harsh restrictions on nitrous oxide emissions because of warming fears are not justified by these facts. restrictions would cause serious harm ; for example, by jeopardizing world food supplies. enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest layer. in all, the atmosphere is made up of about 78. 0 % nitrogen, 20. 9 % oxygen, and 0. 92 % argon, and small amounts of other gases including co2 and water vapor. water vapor and co2 cause the earth ' s atmosphere to catch and hold the sun ' s energy through the greenhouse effect. this makes earth ' s surface warm enough for liquid water and life. in addition to trapping heat, the atmosphere also protects living organisms by shielding the earth ' s surface from cosmic rays. the magnetic field — created by the internal motions of the core — produces the magnetosphere which protects earth ' s atmosphere from the solar wind. as the earth is 4. 5 billion years old, it would have lost its atmosphere by now if there were no protective magnetosphere. = = earth ' s magnetic field = = = = hydrology = = hydrology is the study of the hydrosphere and the movement of water on earth. it emphasizes the study of how humans use and interact with freshwater supplies. study of water ' s movement is closely related to geomorphology and other branches of earth science. applied hydrology involves engineering to maintain aquatic environments and distribute water supplies. subdisciplines of hydrology include oceanography, hydrogeology, ecohydrology, and glaciology. oceanography is the study of oceans. hydrogeology is the study of groundwater. it includes the mapping of groundwater supplies and the analysis of groundwater contaminants. applied hydrogeology seeks to prevent contamination of groundwater and mineral springs and make it available as drinking water. the earliest exploitation of groundwater resources dates back to 3000 bc, and hydrogeology as a science was developed by hydrologists beginning in the 17th century. ecohydrology is the study of ecological systems in the hydrosphere. it can be divided into the physical study of aquatic ecosystems and the variation in total solar irradiance is thought to have little effect on the earth ' s surface temperature because of the thermal time constant - - the characteristic response time of the earth ' s global surface temperature to changes in forcing. this time constant is large enough to smooth annual variations but not necessarily variations having a longer period such as those due to solar inertial motion ; the magnitude of these surface temperature variations is estimated. ambient air ( see lockheed f - 117 nighthawk, rectangular nozzles on the lockheed martin f - 22 raptor, and serrated nozzle flaps on the lockheed martin f - 35 lightning ). often, cool air is deliberately injected into the exhaust flow to boost this process ( see ryan aqm - 91 firefly and northrop b - 2 spirit ). the stefan – boltzmann law shows how this results in less energy ( thermal radiation in infrared spectrum ) being released and thus reduces the heat signature. in some aircraft, the jet exhaust is vented above the wing surface to shield it from observers below, as in the lockheed f - 117 nighthawk, and the unstealthy fairchild republic a - 10 thunderbolt ii. to achieve infrared stealth, the exhaust gas is cooled to the temperatures where the brightest wavelengths it radiates are absorbed by atmospheric carbon dioxide and water vapor, greatly reducing the infrared visibility of the exhaust plume. another way to reduce the exhaust temperature is to circulate coolant fluids such as fuel inside the exhaust pipe, where the fuel tanks serve as heat sinks cooled by the flow of air along the wings. ground combat includes the use of both active and passive infrared sensors. thus, the united states marine corps ( usmc ) ground combat uniform requirements document specifies infrared reflective quality standards. = = reducing radio frequency ( rf ) emissions = = in addition to reducing infrared and acoustic emissions, a stealth vehicle must avoid radiating any other detectable energy, such as from onboard radars, communications systems, or rf leakage from electronics enclosures. the f - 117 uses passive infrared and low light level television sensor systems to aim its weapons and the f - 22 raptor has an advanced lpi radar which can illuminate enemy aircraft without triggering a radar warning receiver response. = = measuring = = the size of a target ' s image on radar is measured by the rcs, often represented by the symbol σ and expressed in square meters. this does not equal geometric area. a perfectly conducting sphere of projected cross sectional area 1 m2 ( i. e. a diameter of 1. 13 m ) will have an rcs of 1 m2. note that for radar wavelengths much less than the diameter of the sphere, rcs is independent of frequency. conversely, a square flat plate of area 1 m2 will have an rcs of σ = 4π a2 / λ2 ( where a = area, λ = wavelength ), or 13, 982 m2 at 10 ghz if the radar is perpendicular to the flat the transition of our energy system to renewable energies is necessary in order not to heat up the climate any further and to achieve climate neutrality. the use of wind energy plays an important role in this transition in germany. but how much wind energy can be used and what are the possible consequences for the atmosphere if more and more wind energy is used? significantly greater strength and fracture toughness. another major change in the body during the firing or sintering process will be the establishment of the polycrystalline nature of the solid. significant grain growth tends to occur during sintering, with this growth depending on temperature and duration of the sintering process. the growth of grains will result in some form of grain size distribution, which will have a significant impact on the ultimate physical properties of the material. in particular, abnormal grain growth in which certain grains grow very large in a matrix of finer grains will significantly alter the physical and mechanical properties of the obtained ceramic. in the sintered body, grain sizes are a product of the thermal processing parameters as well as the initial particle size, or possibly the sizes of aggregates or particle clusters which arise during the initial stages of processing. the ultimate microstructure ( and thus the physical properties ) of the final product will be limited by and subject to the form of the structural template or precursor which is created in the initial stages of chemical synthesis and physical forming. hence the importance of chemical powder and polymer processing as it pertains to the synthesis of industrial ceramics, glasses and glass - ceramics. there are numerous possible refinements of the sintering process. some of the most common involve pressing the green body to give the densification a head start and reduce the sintering time needed. sometimes organic binders such as polyvinyl alcohol are added to hold the green body together ; these burn out during the firing ( at 200 – 350 °c ). sometimes organic lubricants are added during pressing to increase densification. it is common to combine these, and add binders and lubricants to a powder, then press. ( the formulation of these organic chemical additives is an art in itself. this is particularly important in the manufacture of high performance ceramics such as those used by the billions for electronics, in capacitors, inductors, sensors, etc. ) a slurry can be used in place of a powder, and then cast into a desired shape, dried and then sintered. indeed, traditional pottery is done with this type of method, using a plastic mixture worked with the hands. if a mixture of different materials is used together in a ceramic, the sintering temperature is sometimes above the melting point of one minor component – a liquid phase sintering. this results in shorter sintering times compared to solid state sintering. such liquid phase sintering involves in faster diffusion processes and may result in abnormal grain assuming only statistical mechanics and general relativity, we calculate the maximal temperature of gas of particles placed in ads space - time. if two particles with a given center of mass energy come close enough, according to classical gravity they will form a black hole. we focus only on the black holes with hawking temperature lower than the environment, because they do not disappear. the number density of such black holes grows with the temperature in the system. at a certain finite temperature, the thermodynamical system will be dominated by black holes. this critical temperature is lower than the planck temperature for the values of the ads vacuum energy density below the planck density. this result might be interesting from the ads / cft correspondence point of view, since it is different from the hawking - page phase transition, and it is not immediately clear what effect dynamically limits the maximal temperature of the thermal state on the cft side of the correspondence. a minimum atmospheric temperature, or tropopause, occurs at a pressure of around 0. 1 bar in the atmospheres of earth, titan, jupiter, saturn, uranus and neptune, despite great differences in atmospheric composition, gravity, internal heat and sunlight. in all these bodies, the tropopause separates a stratosphere with a temperature profile that is controlled by the absorption of shortwave solar radiation, from a region below characterised by convection, weather, and clouds. however, it is not obvious why the tropopause occurs at the specific pressure near 0. 1 bar. here we use a physically - based model to demonstrate that, at atmospheric pressures lower than 0. 1 bar, transparency to thermal radiation allows shortwave heating to dominate, creating a stratosphere. at higher pressures, atmospheres become opaque to thermal radiation, causing temperatures to increase with depth and convection to ensue. a common dependence of infrared opacity on pressure, arising from the shared physics of molecular absorption, sets the 0. 1 bar tropopause. we hypothesize that a tropopause at a pressure of approximately 0. 1 bar is characteristic of many thick atmospheres, including exoplanets and exomoons in our galaxy and beyond. judicious use of this rule could help constrain the atmospheric structure, and thus the surface environments and habitability, of exoplanets. a new mechanism of adjustment of vacuum energy down to the observed value from an initially huge one is considered. the mechanism is based on a very strong variation of the gravitational coupling constant in very early universe. the model predicts that the non - - compensated remnant of vacuum energy changes very slowly at late stages of the cosmological evolution and is naturally close to the observed one. asymptotically the effective vacuum energy tends to a negative value, so the cosmological expansion should stop and turn into contraction. there remains the problem of introduction of the usual matter into the model and therefore realising realistic cosmology. temperature changes up to 1000 °c. = = processing steps = = the traditional ceramic process generally follows this sequence : milling → batching → mixing → forming → drying → firing → assembly. milling is the process by which materials are reduced from a large size to a smaller size. milling may involve breaking up cemented material ( in which case individual particles retain their shape ) or pulverization ( which involves grinding the particles themselves to a smaller size ). milling is generally done by mechanical means, including attrition ( which is particle - to - particle collision that results in agglomerate break up or particle shearing ), compression ( which applies a forces that results in fracturing ), and impact ( which employs a milling medium or the particles themselves to cause fracturing ). attrition milling equipment includes the wet scrubber ( also called the planetary mill or wet attrition mill ), which has paddles in water creating vortexes in which the material collides and break up. compression mills include the jaw crusher, roller crusher and cone crusher. impact mills include the ball mill, which has media that tumble and fracture the material, or the resonantacoustic mixer. shaft impactors cause particle - to particle attrition and compression. batching is the process of weighing the oxides according to recipes, and preparing them for mixing and drying. mixing occurs after batching and is performed with various machines, such as dry mixing ribbon mixers ( a type of cement mixer ), resonantacoustic mixers, mueller mixers, and pug mills. wet mixing generally involves the same equipment. forming is making the mixed material into shapes, ranging from toilet bowls to spark plug insulators. forming can involve : ( 1 ) extrusion, such as extruding " slugs " to make bricks, ( 2 ) pressing to make shaped parts, ( 3 ) slip casting, as in making toilet bowls, wash basins and ornamentals like ceramic statues. forming produces a " green " part, ready for drying. green parts are soft, pliable, and over time will lose shape. handling the green product will change its shape. for example, a green brick can be " squeezed ", and after squeezing it will stay that way. drying is removing the water or binder from the formed material. spray drying is widely used to prepare powder for pressing operations. other dryers are tunnel dryers and periodic dryers. controlled heat is applied in this two - stage process. first, Question: Air temperature changes as what increases? A) salinity B) altitude C) density D) pressure	B) altitude
Context: in order to obtain the keys in this system, a key must be inserted and turned ( like the key at the bottom of the system of the picture ). once the key is turned, the operator may retrieve the remaining keys that will be used to open other doors. once all keys are returned, then the operator will be allowed to take out the original key from the beginning. the key will not turn unless the remaining keys are put back in place. another example is an electric kiln. to prevent access to the inside of an electric kiln, a trapped key system may be used to interlock a disconnecting switch and the kiln door. while the switch is turned on, the key is held by the interlock attached to the disconnecting switch. to open the kiln door, the switch is first opened, which releases the key. the key can then be used to unlock the kiln door. while the key is removed from the switch interlock, a plunger from the interlock mechanically prevents the switch from closing. power cannot be re - applied to the kiln until the kiln door is locked, releasing the key, and the key is then returned to the disconnecting switch interlock. a similar two - part interlock system can be used anywhere it is necessary to ensure the energy supply to a machine is interrupted before the machine is entered for adjustment or maintenance. = = mechanical = = interlocks may be strictly mechanical. an example of a mechanical interlock is a steering wheel of a car. in modern days, most cars have an anti - theft feature that restricts the turning of the steering wheel if the key is not inserted in the ignition. this prevents an individual from pushing the car since the mechanical interlock restricts the directional motion of the front wheels of the car. in the operation of a device such as a press or cutter that is hand fed or the workpiece hand removed, the use of two buttons to actuate the device, one for each hand, greatly reduces the possibility of operation endangering the operator. no such system is fool - proof, and such systems are often augmented by the use of cable – pulled gloves worn by the operator ; these are retracted away from the danger area by the stroke of the machine. a major problem in engineering operator safety is the tendency of operators to ignore safety precautions or even outright disabling forced interlocks due to work pressure and other factors. therefore, such safeties require and perhaps must facilitate operator cooperation. = = electrical = in a predetermined sequence. after the control or power has been isolated, a key is released that can be used to grant access to individual or multiple doors. below is an example of what a trapped key interlock transfer block would look like. this is a part of a trapped key interlocking system. in order to obtain the keys in this system, a key must be inserted and turned ( like the key at the bottom of the system of the picture ). once the key is turned, the operator may retrieve the remaining keys that will be used to open other doors. once all keys are returned, then the operator will be allowed to take out the original key from the beginning. the key will not turn unless the remaining keys are put back in place. another example is an electric kiln. to prevent access to the inside of an electric kiln, a trapped key system may be used to interlock a disconnecting switch and the kiln door. while the switch is turned on, the key is held by the interlock attached to the disconnecting switch. to open the kiln door, the switch is first opened, which releases the key. the key can then be used to unlock the kiln door. while the key is removed from the switch interlock, a plunger from the interlock mechanically prevents the switch from closing. power cannot be re - applied to the kiln until the kiln door is locked, releasing the key, and the key is then returned to the disconnecting switch interlock. a similar two - part interlock system can be used anywhere it is necessary to ensure the energy supply to a machine is interrupted before the machine is entered for adjustment or maintenance. = = mechanical = = interlocks may be strictly mechanical. an example of a mechanical interlock is a steering wheel of a car. in modern days, most cars have an anti - theft feature that restricts the turning of the steering wheel if the key is not inserted in the ignition. this prevents an individual from pushing the car since the mechanical interlock restricts the directional motion of the front wheels of the car. in the operation of a device such as a press or cutter that is hand fed or the workpiece hand removed, the use of two buttons to actuate the device, one for each hand, greatly reduces the possibility of operation endangering the operator. no such system is fool - proof, and such systems are often augmented by the use of cable – pulled gloves worn by the operator ; these are liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and this process may release or absorb energy. when the resulting nucleus is lighter than that of iron, energy is normally released ; when the nucleus is heavier than that of iron, energy is generally absorbed. this process of fusion occurs in stars, which derive their energy from hydrogen and helium. they form, through stellar nucleosynthesis, the light elements ( lithium to calcium ) as well as some of the heavy elements ( beyond iron and nickel, via the s - process ). the remaining abundance of heavy elements, from nickel to uranium and beyond, is due to supernova nucleosynthesis, the r - process. of course, these natural processes of astrophysics are not examples of nuclear " technology ". because of the very strong repulsion of nuclei, fusion is difficult to achieve in a controlled fashion. hydrogen bombs, formally known as thermonuclear weapons, obtain their enormous destructive power from fusion, but their energy cannot be controlled. controlled fusion is achieved in particle accelerators ; this is how many synthetic elements are produced. a fusor can also produce controlled fusion and is a useful neutron source. however, both of these devices operate at a net energy loss. controlled, viable fusion power has proven elusive, despite the occasional hoax. technical and theoretical difficulties have hindered the development of working civilian fusion technology, though research continues to this day around the world. nuclear fusion was initially pursued only in theoretical stages during world war ii, when scientists on the manhattan project ( led by edward teller ) investigated it as a method to build a bomb. the project abandoned fusion after concluding that it would require a fission reaction to detonate. it took until 1952 for the first full hydrogen bomb to be detonated, so - called because it used reactions between deuterium and tritium. fusion reactions are much more energetic per unit mass of fuel than fission reactions, but starting the fusion chain reaction is much more difficult. = = nuclear weapons = = a nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission or a combination of fission and fusion. both reactions release vast quantities of energy from relatively small amounts of matter. even small nuclear devices can devastate a city by blast, fire and radiation. nuclear weapons are considered weapons of mass destruction, and their use and control has been a major aspect of international policy since their debut. the design of a nuclear weapon is more complicated than it might seem. such a weapon must hold one or more subcritical fissile masses stable for deployment, then induce criticality ##physical processes which take place in human beings as they make sense of information received through the visual system. the subject of the image. when developing an imaging system, designers must consider the observables associated with the subjects which will be imaged. these observables generally take the form of emitted or reflected energy, such as electromagnetic energy or mechanical energy. the capture device. once the observables associated with the subject are characterized, designers can then identify and integrate the technologies needed to capture those observables. for example, in the case of consumer digital cameras, those technologies include optics for collecting energy in the visible portion of the electromagnetic spectrum, and electronic detectors for converting the electromagnetic energy into an electronic signal. the processor. for all digital imaging systems, the electronic signals produced by the capture device must be manipulated by an algorithm which formats the signals so they can be displayed as an image. in practice, there are often multiple processors involved in the creation of a digital image. the display. the display takes the electronic signals which have been manipulated by the processor and renders them on some visual medium. examples include paper ( for printed, or " hard copy " images ), television, computer monitor, or projector. note that some imaging scientists will include additional " links " in their description of the imaging chain. for example, some will include the " source " of the energy which " illuminates " or interacts with the subject of the image. others will include storage and / or transmission systems. = = subfields = = subfields within imaging science include : image processing, computer vision, 3d computer graphics, animations, atmospheric optics, astronomical imaging, biological imaging, digital image restoration, digital imaging, color science, digital photography, holography, magnetic resonance imaging, medical imaging, microdensitometry, optics, photography, remote sensing, radar imaging, radiometry, silver halide, ultrasound imaging, photoacoustic imaging, thermal imaging, visual perception, and various printing technologies. = = methodologies = = acoustic imaging coherent imaging uses an active coherent illumination source, such as in radar, synthetic aperture radar ( sar ), medical ultrasound and optical coherence tomography ; non - coherent imaging systems include fluorescent microscopes, optical microscopes, and telescopes. chemical imaging, the simultaneous measurement of spectra and pictures digital imaging, creating digital images, generally by scanning or through digital photography disk image, a file which contains the exact content of a data storage medium document imaging, replicating documents commonly any two generating systems of the fundamental group of a closed surface are nielsen equivalent. final version. to appear in discrete and continuous dynamical systems - a. other strands of proteins. = = = metabolism = = = all cells require energy to sustain cellular processes. metabolism is the set of chemical reactions in an organism. the three main purposes of metabolism are : the conversion of food to energy to run cellular processes ; the conversion of food / fuel to monomer building blocks ; and the elimination of metabolic wastes. these enzyme - catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. metabolic reactions may be categorized as catabolic — the breaking down of compounds ( for example, the breaking down of glucose to pyruvate by cellular respiration ) ; or anabolic — the building up ( synthesis ) of compounds ( such as proteins, carbohydrates, lipids, and nucleic acids ). usually, catabolism releases energy, and anabolism consumes energy. the chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme. enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. enzymes act as catalysts — they allow a reaction to proceed more rapidly without being consumed by it — by reducing the amount of activation energy needed to convert reactants into products. enzymes also allow the regulation of the rate of a metabolic reaction, for example in response to changes in the cell ' s environment or to signals from other cells. = = = cellular respiration = = = cellular respiration is a set of metabolic reactions and processes that take place in cells to convert chemical energy from nutrients into adenosine triphosphate ( atp ), and then release waste products. the reactions involved in respiration are catabolic reactions, which break large molecules into smaller ones, releasing energy. respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. the overall reaction occurs in a series of biochemical steps, some of which are redox reactions. although cellular respiration is technically a combustion reaction, it clearly does not resemble one when it occurs in a cell because of the slow, controlled release of energy from the series of reactions. sugar in the form of glucose is the main nutrient used by animal and plant cells in respiration. cellular respiration involving oxygen is called aerobic respiration, which has four stages : glycolysis, citric acid cycle ( or krebs cycle substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the ##nosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of Question: What happens to energy in a closed system? A) is wasted B) is conserved C) is destroyed D) is replicated	B) is conserved
Context: cobalt nanowires with a diameter in the range between 50 to 100nm can be prepared as single - crystal wires with the easy axis ( the c - axis ) perpendicular to the wire axis. the competition between the crystal anisotropy and demagnetization energy frustrates the magnetization direction. a periodic modulation of the angle between m and the wire axis yields a lower energy. an alternative explanation of 1 / f - noise in manganites is suggested and discussed ultramagnetized neutron stars or magnetars are magnetically powered neutron stars. their strong magnetic fields dominate the physical processes in their crusts and their surroundings. the past few years have seen several advances in our theoretical and observational understanding of these objects. in spite of a surfeit of observations, their spectra are still poorly understood. i will discuss the emission from strongly magnetized condensed matter surfaces of neutron stars, recent advances in our expectations of the surface composition of magnetars and a model for the non - thermal emission from these objects. torsion oscillations of the neutron star crust are landau damped by the alfven continuum in the bulk. for strong magnetic fields ( in magnetars ), undamped alfven eigenmodes appear. applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales is a commonly used practice that helps better understand the metal ' s elasticity and plasticity for different applications and production processes. in a saltwater environment, most ferrous metals and some non - ferrous alloys corrode quickly. metals exposed to cold or cryogenic conditions may undergo a ductile to brittle transition and lose their toughness, becoming more brittle and prone to cracking. metals under continual cyclic loading can suffer from metal fatigue. metals under constant stress at elevated temperatures can creep. = = = metalworking processes = = = casting – molten metal is poured into a shaped mold. variants of casting include sand casting, investment the valuable metals into individual constituents. = = metal and its alloys = = much effort has been placed on understanding iron – carbon alloy system, which includes steels and cast irons. plain carbon steels ( those that contain essentially only carbon as an alloying element ) are used in low - cost, high - strength applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales is a commonly used practice that helps better understand the metal ' s elasticity and plasticity for different applications and production processes. in a saltwater environment, most ferrous metals and some non - ferrous alloys corrode quickly. metals exposed to cold or cryogenic conditions may undergo a ductile to brittle the magnetization of superconducting samples is influenced by their porosity. in addition to structural modifications and improved cooling, the presence of pores also plays a role in trapping magnetic flux. pores have an impact on the irreversibility field, the full penetration field, and the remnant magnetization. generally, as porosity increases, these parameters tend to decrease. however, in the case of mesoscopic samples or samples with low critical current densities, increased porosity can actually enhance the trapping of magnetic flux. is collected and processed to extract valuable metals. ore bodies often contain more than one valuable metal. tailings of a previous process may be used as a feed in another process to extract a secondary product from the original ore. additionally, a concentrate may contain more than one valuable metal. that concentrate would then be processed to separate the valuable metals into individual constituents. = = metal and its alloys = = much effort has been placed on understanding iron – carbon alloy system, which includes steels and cast irons. plain carbon steels ( those that contain essentially only carbon as an alloying element ) are used in low - cost, high - strength applications, where neither weight nor corrosion are a major concern. cast irons, including ductile iron, are also part of the iron - carbon system. iron - manganese - chromium alloys ( hadfield - type steels ) are also used in non - magnetic applications such as directional drilling. other engineering metals include aluminium, chromium, copper, magnesium, nickel, titanium, zinc, and silicon. these metals are most often used as alloys with the noted exception of silicon, which is not a metal. other forms include : stainless steel, particularly austenitic stainless steels, galvanized steel, nickel alloys, titanium alloys, or occasionally copper alloys are used, where resistance to corrosion is important. aluminium alloys and magnesium alloys are commonly used, when a lightweight strong part is required such as in automotive and aerospace applications. copper - nickel alloys ( such as monel ) are used in highly corrosive environments and for non - magnetic applications. nickel - based superalloys like inconel are used in high - temperature applications such as gas turbines, turbochargers, pressure vessels, and heat exchangers. for extremely high temperatures, single crystal alloys are used to minimize creep. in modern electronics, high purity single crystal silicon is essential for metal - oxide - silicon transistors ( mos ) and integrated circuits. = = production = = in production engineering, metallurgy is concerned with the production of metallic components for use in consumer or engineering products. this involves production of alloys, shaping, heat treatment and surface treatment of product. the task of the metallurgist is to achieve balance between material properties, such as cost, weight, strength, toughness, hardness, corrosion, fatigue resistance and performance in temperature extremes. to achieve this goal, the operating environment must be carefully considered. determining the hardness of the metal using the rockwell, vickers, and brinell hardness scales insights from stripe incommensurabilities and antiferromagnetic stability indicate that the magnetic moments of both host cu ^ 2 + ions and cu atoms from electron doping support the thermal hall effect in cuprates, whereas those of o atoms from hole doping oppose it. two types of stars are known to have strong, large scale magnetic fields : the main sequence ap stars and the magnetic white dwarfs. this suggest that the former might be the progenitors of the latter. in order to test this idea, i have carried out a search for large scale magnetic fields in stars with evolutionary states which are intermediate, i. e. in horizontal branch stars and in hot subdwarfs. Question: What are magnetites naturally attracted to? A) aluminum B) glass C) iron D) stone	C) iron
Context: sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, as subjects perceive the sensory world, different stimuli elicit a number of neural representations. here, a subjective distance between stimuli is defined, measuring the degree of similarity between the underlying representations. as an example, the subjective distance between different locations in space is calculated from the activity of rodent hippocampal place cells, and lateral septal cells. such a distance is compared to the real distance, between locations. as the number of sampled neurons increases, the subjective distance shows a tendency to resemble the metrics of real space. , social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), along with an idea of what needs to be done to obtain a definitive diagnosis that would explain the patient ' s problem. on subsequent visits, the process may be repeated in an abbreviated manner to obtain any new history, symptoms, physical findings, lab or imaging results, or specialist consultations. = = institutions = = contemporary medicine is, in general, conducted within health care systems. legal, credentialing, and financing frameworks are established by individual governments, augmented on occasion by international organizations, such as churches. the characteristics of any given health care system have a significant impact on the way medical care is provided. from ancient times, christian emphasis on practical charity gave rise to the development of systematic nursing and hospitals, and the catholic church today remains the largest non - government provider of medical services in the world. advanced industrial countries ( with the exception of the united states ) and many developing countries provide medical services through a system of universal health care that aims to haptic technology ( also kinaesthetic communication or 3d touch ) is technology that can create an experience of touch by applying forces, vibrations, or motions to the user. these technologies can be used to create virtual objects in a computer simulation, to control virtual objects, and to enhance remote control of machines and devices ( telerobotics ). haptic devices may incorporate tactile sensors that measure forces exerted by the user on the interface. the word haptic, from the ancient greek : απτικος ( haptikos ), means " tactile, pertaining to the sense of touch ". simple haptic devices are common in the form of game controllers, joysticks, and steering wheels. haptic technology facilitates investigation of how the human sense of touch works by allowing the creation of controlled haptic virtual objects. vibrations and other tactile cues have also become an integral part of mobile user experience and interface design. most researchers distinguish three sensory systems related to sense of touch in humans : cutaneous, kinaesthetic and haptic. all perceptions mediated by cutaneous and kinaesthetic sensibility are referred to as tactual perception. the sense of touch may be classified as passive and active, and the term " haptic " is often associated with active touch to communicate or recognize objects. = = history = = one of the earliest applications of haptic technology was in large aircraft that use servomechanism systems to operate control surfaces. in lighter aircraft without servo systems, as the aircraft approached a stall, the aerodynamic buffeting ( vibrations ) was felt in the pilot ' s controls. this was a useful warning of a dangerous flight condition. servo systems tend to be " one - way ", meaning external forces applied aerodynamically to the control surfaces are not perceived at the controls, resulting in the lack of this important sensory cue. to address this, the missing normal forces are simulated with springs and weights. the angle of attack is measured, and as the critical stall point approaches a stick shaker is engaged which simulates the response of a simpler control system. alternatively, the servo force may be measured and the signal directed to a servo system on the control, also known as force feedback. force feedback has been implemented experimentally in some excavators and is useful when excavating mixed material such as large rocks embedded in silt or clay. it allows the operator to " feel " and work around unseen obstacles. in the 1960s, paul bach - passage of carbon dioxide as aluminum and glass. = = = ceramics and glasses = = = another application of materials science is the study of ceramics and glasses, typically the most brittle materials with industrial relevance. many ceramics and glasses exhibit covalent or ionic - covalent bonding with sio2 ( silica ) as a fundamental building block. ceramics – not to be confused with raw, unfired clay – are usually seen in crystalline form. the vast majority of commercial glasses contain a metal oxide fused with silica. at the high temperatures used to prepare glass, the material is a viscous liquid which solidifies into a disordered state upon cooling. windowpanes and eyeglasses are important examples. fibers of glass are also used for long - range telecommunication and optical transmission. scratch resistant corning gorilla glass is a well - known example of the application of materials science to drastically improve the properties of common components. engineering ceramics are known for their stiffness and stability under high temperatures, compression and electrical stress. alumina, silicon carbide, and tungsten carbide are made from a fine powder of their constituents in a process of sintering with a binder. hot pressing provides higher density material. chemical vapor deposition can place a film of a ceramic on another material. cermets are ceramic particles containing some metals. the wear resistance of tools is derived from cemented carbides with the metal phase of cobalt and nickel typically added to modify properties. ceramics can be significantly strengthened for engineering applications using the principle of crack deflection. this process involves the strategic addition of second - phase particles within a ceramic matrix, optimizing their shape, size, and distribution to direct and control crack propagation. this approach enhances fracture toughness, paving the way for the creation of advanced, high - performance ceramics in various industries. = = = composites = = = another application of materials science in industry is making composite materials. these are structured materials composed of two or more macroscopic phases. applications range from structural elements such as steel - reinforced concrete, to the thermal insulating tiles, which play a key and integral role in nasa ' s space shuttle thermal protection system, which is used to protect the surface of the shuttle from the heat of re - entry into the earth ' s atmosphere. one example is reinforced carbon - carbon ( rcc ), the light gray material, which withstands re - entry temperatures up to 1, 510 °c ( 2, 750 °f ) and protects the space shuttle ' s wing leading edges and nose cap in gravitational lensing, the concept of optical depth assumes the lens is dark. several microlensing detections have now been made where the lens may be bright. relations are developed between apparent and absolute optical depth in the regime of the apparent and absolute brightness of the lens. an apparent optical depth through bright lenses is always less than the true, absolute optical depth. the greater the intrinsic brightness of the lens, the more likely it will be found nearer the source. and evaporative emissions. nvh engineering ( noise, vibration, and harshness ) : nvh involves customer feedback ( both tactile [ felt ] and audible [ heard ] ) concerning a vehicle. while sound can be interpreted as a rattle, squeal, or hot, a tactile response can be seat vibration or a buzz in the steering wheel. this feedback is generated by components either rubbing, vibrating, or rotating. nvh response can be classified in various ways : powertrain nvh, road noise, wind noise, component noise, and squeak and rattle. note, there are both good and bad nvh qualities. the nvh engineer works to either eliminate bad nvh or change the " bad nvh " to good ( i. e., exhaust tones ). vehicle electronics : automotive electronics is an increasingly important aspect of automotive engineering. modern vehicles employ dozens of electronic systems. these systems are responsible for operational controls such as the throttle, brake and steering controls ; as well as many comfort - and - convenience systems such as the hvac, infotainment, and lighting systems. it would not be possible for automobiles to meet modern safety and fuel - economy requirements without electronic controls. performance : performance is a measurable and testable value of a vehicle ' s ability to perform in various conditions. performance can be considered in a wide variety of tasks, but it generally considers how quickly a car can accelerate ( e. g. standing start 1 / 4 mile elapsed time, 0 – 60 mph, etc. ), its top speed, how short and quickly a car can come to a complete stop from a set speed ( e. g. 70 - 0 mph ), how much g - force a car can generate without losing grip, recorded lap - times, cornering speed, brake fade, etc. performance can also reflect the amount of control in inclement weather ( snow, ice, rain ). shift quality : shift quality is the driver ' s perception of the vehicle to an automatic transmission shift event. this is influenced by the powertrain ( internal combustion engine, transmission ), and the vehicle ( driveline, suspension, engine and powertrain mounts, etc. ) shift feel is both a tactile ( felt ) and audible ( heard ) response of the vehicle. shift quality is experienced as various events : transmission shifts are felt as an upshift at acceleration ( 1 – 2 ), or a downshift maneuver in passing ( 4 – 2 the injuries of the inundations they have been designed to prevent, as the escape of floods from the raised river must occur sooner or later. inadequate planning controls which have permitted development on floodplains have been blamed for the flooding of domestic properties. channelization was done under the auspices or overall direction of engineers employed by the local authority or the national government. one of the most heavily channelized areas in the united states is west tennessee, where every major stream with one exception ( the hatchie river ) has been partially or completely channelized. channelization of a stream may be undertaken for several reasons. one is to make a stream more suitable for navigation or for navigation by larger vessels with deep draughts. another is to restrict water to a certain area of a stream ' s natural bottom lands so that the bulk of such lands can be made available for agriculture. a third reason is flood control, with the idea of giving a stream a sufficiently large and deep channel so that flooding beyond those limits will be minimal or nonexistent, at least on a routine basis. one major reason is to reduce natural erosion ; as a natural waterway curves back and forth, it usually deposits sand and gravel on the inside of the corners where the water flows slowly, and cuts sand, gravel, subsoil, and precious topsoil from the outside corners where it flows rapidly due to a change in direction. unlike sand and gravel, the topsoil that is eroded does not get deposited on the inside of the next corner of the river. it simply washes away. = = loss of wetlands = = channelization has several predictable and negative effects. one of them is loss of wetlands. wetlands are an excellent habitat for multiple forms of wildlife, and additionally serve as a " filter " for much of the world ' s surface fresh water. another is the fact that channelized streams are almost invariably straightened. for example, the channelization of florida ' s kissimmee river has been cited as a cause contributing to the loss of wetlands. this straightening causes the streams to flow more rapidly, which can, in some instances, vastly increase soil erosion. it can also increase flooding downstream from the channelized area, as larger volumes of water traveling more rapidly than normal can reach choke points over a shorter period of time than they otherwise would, with a net effect of flood control in one area coming at the expense of aggravated flooding in another. in addition, studies have shown that stream channelization results in declines of river fish populations. : 3 - 1ff a one of the most important senses in human life is vision, without it life is totally filled with darkness. according to who globally millions of people are visually impaired estimated there are 285 million, of whom some millions are blind. unfortunately, there are around 2. 4 million people are blind in our beloved country pakistan. human are a crucial part of society and the blind community is a main part of society. the technologies are grown so far to make the life of humans easier more comfortable and more reliable for. however, this disability of the blind community would reduce their chance of using such innovative products. therefore, the visually impaired community believe that they are burden to other societies and they do not capture in normal activities separates the blind people from society and because of this believe did not participate in the normally tasks of society. the visual impair people mainly face most of the problems in this real - time the aim of this work is to turn the real time world into an audio world by telling blind person about the objects in their way and can read printed text. this will enable blind persons to identify the things and read the text without any external help just by using the object detection and reading system in real time. objective of this work : i ) object detection ii ) read printed text, using state - of - the - art ( sota ) technology. Question: The visceral senses are most often below the limit of conscious perception because they are involved in this? A) sensory balance B) homeostatic manipulation C) subtle regulation D) homeostatic regulation	D) homeostatic regulation
Context: the standard theory of ideal gases ignores the interaction of the gas particles with the thermal radiation ( photon gas ) that fills the otherwise vacuum space between them. this is an unphysical feature since every material absorbs and radiates thermal energy. this interaction may be important in gases since the latter, unlike solids and liquids are capable of undergoing conspicuous volume changes. taking it into account makes the behaviour of the ideal gases more realistic and removes gibbs ' paradox. or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as can the apparent complexity we observe in the real world be generated from simple initial conditions via simple, deterministic rules? the recent report on laser cooling of liquid may contradict the law of energy conservation. a discontinuity of a turbulent ideal fluid is considered. it is supposed to be split and dispersed, or spread in the stochastic environment forming a gas without hydrostatic pressure. two equal - mass fragments of a discontinuity are indistinguishable from each other. a gas, that possesses such properties, must behave itself as the madelung medium. ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds index chemical substances. in this scheme each chemical substance is identifiable by a number known as its cas registry number. = = = = molecule = = = = a molecule is the smallest indivisible portion of a pure chemical substance that has its unique set of chemical properties, that is, its potential to undergo a certain set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry often called its structure. while the structure of diatomic, triatomic or tetra - atomic molecules may be trivial, ( linear, angular pyramidal etc. ) the structure of polyatomic molecules, that are constituted of more than six atoms ( of several elements ) can be crucial for its chemical nature. = = = = substance and mixture = = = = a chemical substance is a kind of matter with a definite composition and set of properties. a collection of substances is called a mixture. examples of mixtures are air and alloys. = = = = mole and amount of substance = = = = the mole is a unit of measurement that denotes an amount of substance ( also called chemical amount ). one mole is defined to contain exactly 6. 02214076×1023 particles ( atoms, molecules, ions, or electrons ), where the number of particles per mole is known as the avogadro constant. molar concentration is the amount of a particular substance per volume of solution, and is commonly reported in mol / dm3. = = = phase = = = in addition to the specific chemical properties that distinguish different chemical classifications, chemicals can exist in several phases. for the most part, the chemical classifications are independent of these bulk phase some examples and basic properties of ultrametric spaces are briefly discussed. Question: The ideal gas law does not require that the properties of what? A) liquid change B) copper change C) gas change D) transit change	C) gas change
Context: medical purposes. cells are often ' seeded ' into these structures capable of supporting three - dimensional tissue formation. scaffolds mimic the extracellular matrix of the native tissue, recapitulating the in vivo milieu and allowing cells to influence their own microenvironments. they usually serve at least one of the following purposes : allowing cell attachment and migration, delivering and retaining cells and biochemical factors, enabling diffusion of vital cell nutrients and expressed products, and exerting certain mechanical and biological influences to modify the behaviour of the cell phase. in 2009, an interdisciplinary team led by the thoracic surgeon thorsten walles implanted the first bioartificial transplant that provides an innate vascular network for post - transplant graft supply successfully into a patient awaiting tracheal reconstruction. to achieve the goal of tissue reconstruction, scaffolds must meet some specific requirements. high porosity and adequate pore size are necessary to facilitate cell seeding and diffusion throughout the whole structure of both cells and nutrients. biodegradability is often an essential factor since scaffolds should preferably be absorbed by the surrounding tissues without the necessity of surgical removal. the rate at which degradation occurs has to coincide as much as possible with the rate of tissue formation : this means that while cells are fabricating their own natural matrix structure around themselves, the scaffold is able to provide structural integrity within the body and eventually it will break down leaving the newly formed tissue which will take over the mechanical load. injectability is also important for clinical uses. recent research on organ printing is showing how crucial a good control of the 3d environment is to ensure reproducibility of experiments and offer better results. = = = materials = = = material selection is an essential aspect of producing a scaffold. the materials utilized can be natural or synthetic and can be biodegradable or non - biodegradable. additionally, they must be biocompatible, meaning that they do not cause any adverse effects to cells. silicone, for example, is a synthetic, non - biodegradable material commonly used as a drug delivery material, while gelatin is a biodegradable, natural material commonly used in cell - culture scaffolds the material needed for each application is different, and dependent on the desired mechanical properties of the material. tissue engineering of long bone defects for example, will require a rigid scaffold with a compressive strength similar to that of cortical bone ( 100 - 150 mpa ), required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the the clinical symptoms of pulmonary embolism ( pe ) are very diverse and non - specific, which makes it difficult to diagnose. in addition, pulmonary embolism has multiple triggers and is one of the major causes of vascular death. therefore, if it can be detected and treated quickly, it can significantly reduce the risk of death in hospitalized patients. in the detection process, the cost of computed tomography pulmonary angiography ( ctpa ) is high, and angiography requires the injection of contrast agents, which increase the risk of damage to the patient. therefore, this study will use a deep learning approach to detect pulmonary embolism in all patients who take a ct image of the chest using a convolutional neural network. with the proposed pulmonary embolism detection system, we can detect the possibility of pulmonary embolism at the same time as the patient ' s first ct image, and schedule the ctpa test immediately, saving more than a week of ct image screening time and providing timely diagnosis and treatment to the patient. parametric excitation of rotons by oscillating electric field exhibits a narrow resonance at the roton minimum frequency. the resonance width is in good agreement with experimental results on the microwave absorption in superfluid helium. oxygen ion migration in li2mno3 was systematically studied by first - principles calculations. hole polaron is found effective to lower the migration barrier of oxygen ion. fluid dynamics video demonstrating the evolution of dynamic stall on a wind turbine blade. . additionally, there are more sophisticated vr systems being developed which allow the user to use their entire body in their recovery. it also has sophisticated sensors that would allow medical professionals to collect data on muscle engagement and tension. it uses electrical impedance tomography, a form of noninvasive imaging to view muscle usage. another concern is the lack of major funding by big companies and the government into the field. many of these vr sets are off the shelf items, and not properly made for medical use. external add - ones are usually 3d printed or made from spare parts from other electronics. this lack of support means that patients who want to try this method have to be technically savvy, which is unlikely as many ailments only appear later in life. additionally, certain parts of vr like haptic feedback and tracking are still not advanced enough to be used reliably in a medical setting. another issue is the amount of vr devices that are available for purchase. while this does increase the options available, the differences between vr systems could impact patient recovery. the vast number of vr devices also makes it difficult for medical professionals to give and interpret information, as they might not have had practice with the specific model, which could lead to faulty advice being given out. = = = applications = = = currently other applications within healthcare are being explored, such as : applications for monitoring of glucose, alcohol, and lactate or blood oxygen, breath monitoring, heartbeat, heart rate and its variability, electromyography ( emg ), electrocardiogram ( ecg ) and electroencephalogram ( eeg ), body temperature, pressure ( e. g. in shoes ), sweat rate or sweat loss, levels of uric acid and ions – e. g. for preventing fatigue or injuries or for optimizing training patterns, including via " human - integrated electronics " forecasting changes in mood, stress, and health measuring blood alcohol content measuring athletic performance monitoring how sick the user is detecting early signs of infection long - term monitoring of patients with heart and circulatory problems that records an electrocardiogram and is self - moistening health risk assessment applications, including measures of frailty and risks of age - dependent diseases automatic documentation of care activities days - long continuous imaging of diverse organs via a wearable bioadhesive stretchable high - resolution ultrasound imaging patch or e. g. a wearable continuous heart ultrasound imager. ( potential novel diagnostic and monitoring tools ) sleep tracking cortisol monitoring for measuring stress measuring relaxation or alert the numerical radius of the general $ 2 \ times2 $ complex matrix is calculated. , behind which are structures termed reentrant triangles. radar waves penetrating the skin get trapped in these structures, reflecting off the internal faces and losing energy. this method was first used on the blackbird series : a - 12, yf - 12a, lockheed sr - 71 blackbird. the most efficient way to reflect radar waves back to the emitting radar is with orthogonal metal plates, forming a corner reflector consisting of either a dihedral ( two plates ) or a trihedral ( three orthogonal plates ). this configuration occurs in the tail of a conventional aircraft, where the vertical and horizontal components of the tail are set at right angles. stealth aircraft such as the f - 117 use a different arrangement, tilting the tail surfaces to reduce corner reflections formed between them. a more radical method is to omit the tail, as in the b - 2 spirit. the b - 2 ' s clean, low - drag flying wing configuration gives it exceptional range and reduces its radar profile. the flying wing design most closely resembles a so - called infinite flat plate ( as vertical control surfaces dramatically increase rcs ), the perfect stealth shape, as it would have no angles to reflect back radar waves. in addition to altering the tail, stealth design must bury the engines within the wing or fuselage, or in some cases where stealth is applied to an extant aircraft, install baffles in the air intakes, so that the compressor blades are not visible to radar. a stealthy shape must be devoid of complex bumps or protrusions of any kind, meaning that weapons, fuel tanks, and other stores must not be carried externally. any stealthy vehicle becomes un - stealthy when a door or hatch opens. parallel alignment of edges or even surfaces is also often used in stealth designs. the technique involves using a small number of edge orientations in the shape of the structure. for example, on the f - 22a raptor, the leading edges of the wing and the tail planes are set at the same angle. other smaller structures, such as the air intake bypass doors and the air refueling aperture, also use the same angles. the effect of this is to return a narrow radar signal in a very specific direction away from the radar emitter rather than returning a diffuse signal detectable at many angles. the effect is sometimes called " glitter " after the very brief signal seen when the reflected beam passes across a detector. it can be difficult for the radar operator to distinguish between a glitter event and a digital glitch in the processing system. stealth air examples are given of the usefulness of electrons in interaction with nuclei for probing fundamental interactions and structure Question: Vertebrates lacking what structures often use lungs for gas exchange? A) gills B) nostrils C) spores D) pores	A) gills
Context: remediation include ; soil contamination, hazardous waste, groundwater contamination, oil, gas and chemical spills. there are three most common types of environmental remediation. these include soil, water, and sediment remediation. soil remediation consists of removing contaminants in soil, as these pose great risks to humans and the ecosystem. some examples of this are heavy metals, pesticides, and radioactive materials. depending on the contaminant the remedial processes can be physical, chemical, thermal, or biological. water remediation is one of the most important considering water is an essential natural resource. depending on the source of water there will be different contaminants. surface water contamination mainly consists of agricultural, animal, and industrial waste, as well as acid mine drainage. there has been a rise in the need for water remediation due to the increased discharge of industrial waste, leading to a demand for sustainable water solutions. the market for water remediation is expected to consistently increase to $ 19. 6 billion by 2030. sediment remediation consists of removing contaminated sediments. is it almost similar to soil remediation except it is often more sophisticated as it involves additional contaminants. to reduce the contaminants it is likely to use physical, chemical, and biological processes that help with source control, but if these processes are executed correctly, there ' s a risk of contamination resurfacing. = = = solid waste management = = = solid waste management is the purification, consumption, reuse, disposal, and treatment of solid waste that is undertaken by the government or the ruling bodies of a city / town. it refers to the collection, treatment, and disposal of non - soluble, solid waste material. solid waste is associated with both industrial, institutional, commercial and residential activities. hazardous solid waste, when improperly disposed can encourage the infestation of insects and rodents, contributing to the spread of diseases. some of the most common types of solid waste management include ; landfills, vermicomposting, composting, recycling, and incineration. however, a major barrier for solid waste management practices is the high costs associated with recycling and the risks of creating more pollution. = = = e - waste recycling = = = the recycling of electronic waste ( e - waste ) has seen significant technological advancements due to increasing environmental concerns and the growing volume of electronic product disposals. traditional e - waste recycling methods, which often involve manual disassemb = = = = = = environmental remediation = = = environmental remediation is the process through which contaminants or pollutants in soil, water and other media are removed to improve environmental quality. the main focus is the reduction of hazardous substances within the environment. some of the areas involved in environmental remediation include ; soil contamination, hazardous waste, groundwater contamination, oil, gas and chemical spills. there are three most common types of environmental remediation. these include soil, water, and sediment remediation. soil remediation consists of removing contaminants in soil, as these pose great risks to humans and the ecosystem. some examples of this are heavy metals, pesticides, and radioactive materials. depending on the contaminant the remedial processes can be physical, chemical, thermal, or biological. water remediation is one of the most important considering water is an essential natural resource. depending on the source of water there will be different contaminants. surface water contamination mainly consists of agricultural, animal, and industrial waste, as well as acid mine drainage. there has been a rise in the need for water remediation due to the increased discharge of industrial waste, leading to a demand for sustainable water solutions. the market for water remediation is expected to consistently increase to $ 19. 6 billion by 2030. sediment remediation consists of removing contaminated sediments. is it almost similar to soil remediation except it is often more sophisticated as it involves additional contaminants. to reduce the contaminants it is likely to use physical, chemical, and biological processes that help with source control, but if these processes are executed correctly, there ' s a risk of contamination resurfacing. = = = solid waste management = = = solid waste management is the purification, consumption, reuse, disposal, and treatment of solid waste that is undertaken by the government or the ruling bodies of a city / town. it refers to the collection, treatment, and disposal of non - soluble, solid waste material. solid waste is associated with both industrial, institutional, commercial and residential activities. hazardous solid waste, when improperly disposed can encourage the infestation of insects and rodents, contributing to the spread of diseases. some of the most common types of solid waste management include ; landfills, vermicomposting, composting, recycling, and incineration. however, a major barrier for solid waste management practices is the high costs associated with recycling manifold of dimension two ( see § topological surface ). a differentiable surface is a surfaces that is a differentiable manifold ( see § differentiable surface ). every differentiable surface is a topological surface, but the converse is false. a " surface " is often implicitly supposed to be contained in a euclidean space of dimension 3, typically r3. a surface that is contained in a projective space is called a projective surface ( see § projective surface ). a surface that is not supposed to be included in another space is called an abstract surface. = = examples = = the graph of a continuous function of two variables, defined over a connected open subset of r2 is a topological surface. if the function is differentiable, the graph is a differentiable surface. a plane is both an algebraic surface and a differentiable surface. it is also a ruled surface and a surface of revolution. a circular cylinder ( that is, the locus of a line crossing a circle and parallel to a given direction ) is an algebraic surface and a differentiable surface. a circular cone ( locus of a line crossing a circle, and passing through a fixed point, the apex, which is outside the plane of the circle ) is an algebraic surface which is not a differentiable surface. if one removes the apex, the remainder of the cone is the union of two differentiable surfaces. the surface of a polyhedron is a topological surface, which is neither a differentiable surface nor an algebraic surface. a hyperbolic paraboloid ( the graph of the function z = xy ) is a differentiable surface and an algebraic surface. it is also a ruled surface, and, for this reason, is often used in architecture. a two - sheet hyperboloid is an algebraic surface and the union of two non - intersecting differentiable surfaces. = = parametric surface = = a parametric surface is the image of an open subset of the euclidean plane ( typically r 2 { \ displaystyle \ mathbb { r } ^ { 2 } } ) by a continuous function, in a topological space, generally a euclidean space of dimension at least three. usually the function is supposed to be continuously differentiable, and this will be always the case in this article. specifically, a parametric surface in r 3 { \ displaystyle \ mathbb { r } ^ { 3 } } is given by three functions of two variables u and v, called parameters x = f 1 ( u, v ), y = f 2 ( u, v ), z = f 3 the surface of the membrane, retentate is removed from the same side further downstream, whereas the permeate flow is tracked on the other side. in dead - end filtration, the direction of the fluid flow is normal to the membrane surface. both flow geometries offer some advantages and disadvantages. generally, dead - end filtration is used for feasibility studies on a laboratory scale. the dead - end membranes are relatively easy to fabricate which reduces the cost of the separation process. the dead - end membrane separation process is easy to implement and the process is usually cheaper than cross - flow membrane filtration. the dead - end filtration process is usually a batch - type process, where the filtering solution is loaded ( or slowly fed ) into the membrane device, which then allows passage of some particles subject to the driving force. the main disadvantage of dead - end filtration is the extensive membrane fouling and concentration polarization. the fouling is usually induced faster at higher driving forces. membrane fouling and particle retention in a feed solution also builds up a concentration gradients and particle backflow ( concentration polarization ). the tangential flow devices are more cost and labor - intensive, but they are less susceptible to fouling due to the sweeping effects and high shear rates of the passing flow. the most commonly used synthetic membrane devices ( modules ) are flat sheets / plates, spiral wounds, and hollow fibers. flat membranes used in filtration and separation processes can be enhanced with surface patterning, where microscopic structures are introduced to improve performance. these patterns increase surface area, optimize water flow, and reduce fouling, leading to higher permeability and longer membrane lifespan. research has shown that such modifications can significantly enhance efficiency in water purification, energy applications, and industrial separations. flat plates are usually constructed as circular thin flat membrane surfaces to be used in dead - end geometry modules. spiral wounds are constructed from similar flat membranes but in the form of a " pocket " containing two membrane sheets separated by a highly porous support plate. several such pockets are then wound around a tube to create a tangential flow geometry and to reduce membrane fouling. hollow fiber modules consist of an assembly of self - supporting fibers with dense skin separation layers, and a more open matrix helping to withstand pressure gradients and maintain structural integrity. the hollow fiber modules can contain up to 10, 000 fibers ranging from 200 to 2500 μm in diameter ; the main advantage of hollow fiber modules is the very large surface area within dimension 3, typically r3. a surface that is contained in a projective space is called a projective surface ( see § projective surface ). a surface that is not supposed to be included in another space is called an abstract surface. = = examples = = the graph of a continuous function of two variables, defined over a connected open subset of r2 is a topological surface. if the function is differentiable, the graph is a differentiable surface. a plane is both an algebraic surface and a differentiable surface. it is also a ruled surface and a surface of revolution. a circular cylinder ( that is, the locus of a line crossing a circle and parallel to a given direction ) is an algebraic surface and a differentiable surface. a circular cone ( locus of a line crossing a circle, and passing through a fixed point, the apex, which is outside the plane of the circle ) is an algebraic surface which is not a differentiable surface. if one removes the apex, the remainder of the cone is the union of two differentiable surfaces. the surface of a polyhedron is a topological surface, which is neither a differentiable surface nor an algebraic surface. a hyperbolic paraboloid ( the graph of the function z = xy ) is a differentiable surface and an algebraic surface. it is also a ruled surface, and, for this reason, is often used in architecture. a two - sheet hyperboloid is an algebraic surface and the union of two non - intersecting differentiable surfaces. = = parametric surface = = a parametric surface is the image of an open subset of the euclidean plane ( typically r 2 { \ displaystyle \ mathbb { r } ^ { 2 } } ) by a continuous function, in a topological space, generally a euclidean space of dimension at least three. usually the function is supposed to be continuously differentiable, and this will be always the case in this article. specifically, a parametric surface in r 3 { \ displaystyle \ mathbb { r } ^ { 3 } } is given by three functions of two variables u and v, called parameters x = f 1 ( u, v ), y = f 2 ( u, v ), z = f 3 ( u, v ). { \ displaystyle { \ begin { aligned } x & = f _ { 1 } ( u, v ), \ \ [ 4pt ] y & = f _ { 2 } ( u, v ), \ \ [ 4pt ] z & = f _ { 3 } delay of ripening, increase of juice yield, and improvement of re - hydration. irradiation is a more general term of deliberate exposure of materials to radiation to achieve a technical goal ( in this context ' ionizing radiation ' is implied ). as such it is also used on non - food items, such as medical hardware, plastics, tubes for gas - pipelines, hoses for floor - heating, shrink - foils for food packaging, automobile parts, wires and cables ( isolation ), tires, and even gemstones. compared to the amount of food irradiated, the volume of those every - day applications is huge but not noticed by the consumer. the genuine effect of processing food by ionizing radiation relates to damages to the dna, the basic genetic information for life. microorganisms can no longer proliferate and continue their malignant or pathogenic activities. spoilage causing micro - organisms cannot continue their activities. insects do not survive or become incapable of procreation. plants cannot continue the natural ripening or aging process. all these effects are beneficial to the consumer and the food industry, likewise. the amount of energy imparted for effective food irradiation is low compared to cooking the same ; even at a typical dose of 10 kgy most food, which is ( with regard to warming ) physically equivalent to water, would warm by only about 2. 5 °c ( 4. 5 °f ). the specialty of processing food by ionizing radiation is the fact, that the energy density per atomic transition is very high, it can cleave molecules and induce ionization ( hence the name ) which cannot be achieved by mere heating. this is the reason for new beneficial effects, however at the same time, for new concerns. the treatment of solid food by ionizing radiation can provide an effect similar to heat pasteurization of liquids, such as milk. however, the use of the term, cold pasteurization, to describe irradiated foods is controversial, because pasteurization and irradiation are fundamentally different processes, although the intended end results can in some cases be similar. detractors of food irradiation have concerns about the health hazards of induced radioactivity. a report for the industry advocacy group american council on science and health entitled " irradiated foods " states : " the types of radiation sources approved for the treatment of foods have specific energy levels well below that which would cause any element in food to become radioactive. food undergoing irradiation does not become any more ##nts from the air to reduce the potential adverse effects on humans and the environment. the process of air purification may be performed using methods such as mechanical filtration, ionization, activated carbon adsorption, photocatalytic oxidation, and ultraviolet light germicidal irradiation. = = = sewage treatment = = = = = = environmental remediation = = = environmental remediation is the process through which contaminants or pollutants in soil, water and other media are removed to improve environmental quality. the main focus is the reduction of hazardous substances within the environment. some of the areas involved in environmental remediation include ; soil contamination, hazardous waste, groundwater contamination, oil, gas and chemical spills. there are three most common types of environmental remediation. these include soil, water, and sediment remediation. soil remediation consists of removing contaminants in soil, as these pose great risks to humans and the ecosystem. some examples of this are heavy metals, pesticides, and radioactive materials. depending on the contaminant the remedial processes can be physical, chemical, thermal, or biological. water remediation is one of the most important considering water is an essential natural resource. depending on the source of water there will be different contaminants. surface water contamination mainly consists of agricultural, animal, and industrial waste, as well as acid mine drainage. there has been a rise in the need for water remediation due to the increased discharge of industrial waste, leading to a demand for sustainable water solutions. the market for water remediation is expected to consistently increase to $ 19. 6 billion by 2030. sediment remediation consists of removing contaminated sediments. is it almost similar to soil remediation except it is often more sophisticated as it involves additional contaminants. to reduce the contaminants it is likely to use physical, chemical, and biological processes that help with source control, but if these processes are executed correctly, there ' s a risk of contamination resurfacing. = = = solid waste management = = = solid waste management is the purification, consumption, reuse, disposal, and treatment of solid waste that is undertaken by the government or the ruling bodies of a city / town. it refers to the collection, treatment, and disposal of non - soluble, solid waste material. solid waste is associated with both industrial, institutional, commercial and residential activities. hazardous solid waste, when improperly disposed can encourage the generally, dead - end filtration is used for feasibility studies on a laboratory scale. the dead - end membranes are relatively easy to fabricate which reduces the cost of the separation process. the dead - end membrane separation process is easy to implement and the process is usually cheaper than cross - flow membrane filtration. the dead - end filtration process is usually a batch - type process, where the filtering solution is loaded ( or slowly fed ) into the membrane device, which then allows passage of some particles subject to the driving force. the main disadvantage of dead - end filtration is the extensive membrane fouling and concentration polarization. the fouling is usually induced faster at higher driving forces. membrane fouling and particle retention in a feed solution also builds up a concentration gradients and particle backflow ( concentration polarization ). the tangential flow devices are more cost and labor - intensive, but they are less susceptible to fouling due to the sweeping effects and high shear rates of the passing flow. the most commonly used synthetic membrane devices ( modules ) are flat sheets / plates, spiral wounds, and hollow fibers. flat membranes used in filtration and separation processes can be enhanced with surface patterning, where microscopic structures are introduced to improve performance. these patterns increase surface area, optimize water flow, and reduce fouling, leading to higher permeability and longer membrane lifespan. research has shown that such modifications can significantly enhance efficiency in water purification, energy applications, and industrial separations. flat plates are usually constructed as circular thin flat membrane surfaces to be used in dead - end geometry modules. spiral wounds are constructed from similar flat membranes but in the form of a " pocket " containing two membrane sheets separated by a highly porous support plate. several such pockets are then wound around a tube to create a tangential flow geometry and to reduce membrane fouling. hollow fiber modules consist of an assembly of self - supporting fibers with dense skin separation layers, and a more open matrix helping to withstand pressure gradients and maintain structural integrity. the hollow fiber modules can contain up to 10, 000 fibers ranging from 200 to 2500 μm in diameter ; the main advantage of hollow fiber modules is the very large surface area within an enclosed volume, increasing the efficiency of the separation process. the disc tube module uses a cross - flow geometry and consists of a pressure tube and hydraulic discs, which are held by a central tension rod, and membrane cushions that lie between two discs. = = membrane performance and governing equations = = the selection of synthetic membranes , which are not contained in any other space. on the other hand, this excludes surfaces that have singularities, such as the vertex of a conical surface or points where a surface crosses itself. in classical geometry, a surface is generally defined as a locus of a point or a line. for example, a sphere is the locus of a point which is at a given distance of a fixed point, called the center ; a conical surface is the locus of a line passing through a fixed point and crossing a curve ; a surface of revolution is the locus of a curve rotating around a line. a ruled surface is the locus of a moving line satisfying some constraints ; in modern terminology, a ruled surface is a surface, which is a union of lines. = = terminology = = there are several kinds of surfaces that are considered in mathematics. an unambiguous terminology is thus necessary to distinguish them when needed. a topological surface is a surface that is a manifold of dimension two ( see § topological surface ). a differentiable surface is a surfaces that is a differentiable manifold ( see § differentiable surface ). every differentiable surface is a topological surface, but the converse is false. a " surface " is often implicitly supposed to be contained in a euclidean space of dimension 3, typically r3. a surface that is contained in a projective space is called a projective surface ( see § projective surface ). a surface that is not supposed to be included in another space is called an abstract surface. = = examples = = the graph of a continuous function of two variables, defined over a connected open subset of r2 is a topological surface. if the function is differentiable, the graph is a differentiable surface. a plane is both an algebraic surface and a differentiable surface. it is also a ruled surface and a surface of revolution. a circular cylinder ( that is, the locus of a line crossing a circle and parallel to a given direction ) is an algebraic surface and a differentiable surface. a circular cone ( locus of a line crossing a circle, and passing through a fixed point, the apex, which is outside the plane of the circle ) is an algebraic surface which is not a differentiable surface. if one removes the apex, the remainder of the cone is the union of two differentiable surfaces. the surface of a polyhedron is a topological surface, which is neither a differentiable surface nor an algebraic surface. a hyperbolic paraboloid ( the graph of the function z = xy ) is a differentiable surface and onset of electro - chemical corrosion. similar problems are encountered in coastal and offshore structures. = = = anti - fouling = = = anti - fouling is the process of eliminating obstructive organisms from essential components of seawater systems. depending on the nature and location of marine growth, this process is performed in a number of different ways : marine organisms may grow and attach to the surfaces of the outboard suction inlets used to obtain water for cooling systems. electro - chlorination involves running high electrical current through sea water, altering the water ' s chemical composition to create sodium hypochlorite, purging any bio - matter. an electrolytic method of anti - fouling involves running electrical current through two anodes ( scardino, 2009 ). these anodes typically consist of copper and aluminum ( or alternatively, iron ). the first metal, copper anode, releases its ion into the water, creating an environment that is too toxic for bio - matter. the second metal, aluminum, coats the inside of the pipes to prevent corrosion. other forms of marine growth such as mussels and algae may attach themselves to the bottom of a ship ' s hull. this growth interferes with the smoothness and uniformity of the ship ' s hull, causing the ship to have a less hydrodynamic shape that causes it to be slower and less fuel - efficient. marine growth on the hull can be remedied by using special paint that prevents the growth of such organisms. = = = pollution control = = = = = = = sulfur emission = = = = the burning of marine fuels releases harmful pollutants into the atmosphere. ships burn marine diesel in addition to heavy fuel oil. heavy fuel oil, being the heaviest of refined oils, releases sulfur dioxide when burned. sulfur dioxide emissions have the potential to raise atmospheric and ocean acidity causing harm to marine life. however, heavy fuel oil may only be burned in international waters due to the pollution created. it is commercially advantageous due to the cost effectiveness compared to other marine fuels. it is prospected that heavy fuel oil will be phased out of commercial use by the year 2020 ( smith, 2018 ). = = = = oil and water discharge = = = = water, oil, and other substances collect at the bottom of the ship in what is known as the bilge. bilge water is pumped overboard, but must pass a pollution threshold test of 15 ppm ( parts per million ) of oil to be discharged. water is tested Question: What "kind" of water may take longer to become contaminated than surface water, while the natural cleaning process may take longer? A) dam water B) groundwater C) lake water D) spring water	B) groundwater
Context: c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy ". = = extraction = = extractive metallurgy is the practice of removing valuable metals from an ore and refining the extracted raw metals into a purer form. in order to convert a metal oxide or sulphide to a purer metal, the ore must be reduced physically, chemically, or electroly in isotope dating states : there are only three quite technical instances where a half - life changes, and these do not affect the dating methods : " only one technical exception occurs under terrestrial conditions, and this is not for an isotope used for dating.... the artificially - produced isotope, beryllium - 7 has been shown to change by up to 1. 5 %, depending on its chemical environment.... heavier atoms are even less subject to these minute changes, so the dates of rocks made by electron - capture decays would only be off by at most a few hundredths of a percent. " "... another case is material inside of stars, which is in a plasma state where electrons are not bound to atoms. in the extremely hot stellar environment, a completely different kind of decay can occur. ' bound - state beta decay ' occurs when the nucleus emits an electron into a bound electronic state close to the nucleus.... all normal matter, such as everything on earth, the moon, meteorites, etc. has electrons in normal positions, so these instances never apply to rocks, or anything colder than several hundred thousand degrees. " " the last case also involves very fast - moving matter. it has been demonstrated by atomic clocks in very fast spacecraft. these atomic clocks slow down very slightly ( only a second or so per year ) as predicted by einstein ' s theory of relativity. no rocks in our solar system are going fast enough to make a noticeable change in their dates. " = = = = radiohaloes = = = = in the 1970s, young earth creationist robert v. gentry proposed that radiohaloes in certain granites represented evidence for the earth being created instantaneously rather than gradually. this idea has been criticized by physicists and geologists on many grounds including that the rocks gentry studied were not primordial and that the radionuclides in question need not have been in the rocks initially. thomas a. baillieul, a geologist and retired senior environmental scientist with the united states department of energy, disputed gentry ' s claims in an article entitled, " ' polonium haloes ' refuted : a review of ' radioactive halos in a radio - chronological and cosmological perspective ' by robert v. gentry. " baillieul noted that gentry was a physicist with no background in geology and given the absence of this background, gentry had misrepresented the geological context from which the specimens were collected. additionally, he noted that gentry relied on research from the ##elting. metallurgy of lead has also been found in the balkans during the same period. copper smelting is documented at sites in anatolia and at the site of tal - i iblis in southeastern iran from c. 5000 bc. copper smelting is first documented in the delta region of northern egypt in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and medieval india, ancient and medieval japan, amongst others. a 16th century book by georg agricola, de re metallica, describes the highly developed and complex processes of mining metal ores, metal extraction, and metallurgy of the time. agricola has been described as the " father of metallurgy ". = = extraction = = extractive metallurgy is the practice of removing valuable metals from an ore and refining the extracted raw metals into a purer form. in order to convert a metal oxide or sulphide to a purer metal, the ore must be reduced physically, chemically, or electrolytically. extractive metallurgists are interested in three primary streams : feed, concentrate ( metal oxide / sulphide ) and tailings ( waste ). after mining, large pieces of the ore feed are broken through crushing or grinding in order to obtain particles small enough, where each particle is either mostly valuable or be the more significant to modern soil theory than fallou ' s. previously, soil had been considered a product of chemical transformations of rocks, a dead substrate from which plants derive nutritious elements. soil and bedrock were in fact equated. dokuchaev considers the soil as a natural body having its own genesis and its own history of development, a body with complex and multiform processes taking place within it. the soil is considered as different from bedrock. the latter becomes soil under the influence of a series of soil - formation factors ( climate, vegetation, country, relief and age ). according to him, soil should be called the " daily " or outward horizons of rocks regardless of the type ; they are changed naturally by the common effect of water, air and various kinds of living and dead organisms. a 1914 encyclopedic definition : " the different forms of earth on the surface of the rocks, formed by the breaking down or weathering of rocks ". serves to illustrate the historic view of soil which persisted from the 19th century. dokuchaev ' s late 19th century soil concept developed in the 20th century to one of soil as earthy material that has been altered by living processes. a corollary concept is that soil without a living component is simply a part of earth ' s outer layer. further refinement of the soil concept is occurring in view of an appreciation of energy transport and transformation within soil. the term is popularly applied to the material on the surface of the earth ' s moon and mars, a usage acceptable within a portion of the scientific community. accurate to this modern understanding of soil is nikiforoff ' s 1959 definition of soil as the " excited skin of the sub aerial part of the earth ' s crust ". = = areas of practice = = academically, soil scientists tend to be drawn to one of five areas of specialization : microbiology, pedology, edaphology, physics, or chemistry. yet the work specifics are very much dictated by the challenges facing our civilization ' s desire to sustain the land that supports it, and the distinctions between the sub - disciplines of soil science often blur in the process. soil science professionals commonly stay current in soil chemistry, soil physics, soil microbiology, pedology, and applied soil science in related disciplines. one exciting effort drawing in soil scientists in the u. s. as of 2004 is the soil quality initiative. central to the soil quality initiative is developing indices of soil health and then monitoring them in a way have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became other contemporary production centre. the earliest documented use of lead ( possibly native or smelted ) in the near east dates from the 6th millennium bc, is from the late neolithic settlements of yarim tepe and arpachiyah in iraq. the artifacts suggest that lead smelting may have predated copper smelting. metallurgy of lead has also been found in the balkans during the same period. copper smelting is documented at sites in anatolia and at the site of tal - i iblis in southeastern iran from c. 5000 bc. copper smelting is first documented in the delta region of northern egypt in c. 4000 bc, associated with the maadi culture. this represents the earliest evidence for smelting in africa. the varna necropolis, bulgaria, is a burial site located in the western industrial zone of varna, approximately 4 km from the city centre, internationally considered one of the key archaeological sites in world prehistory. the oldest gold treasure in the world, dating from 4, 600 bc to 4, 200 bc, was discovered at the site. the gold piece dating from 4, 500 bc, found in 2019 in durankulak, near varna is another important example. other signs of early metals are found from the third millennium bc in palmela, portugal, los millares, spain, and stonehenge, united kingdom. the precise beginnings, however, have not be clearly ascertained and new discoveries are both continuous and ongoing. in approximately 1900 bc, ancient iron smelting sites existed in tamil nadu. in the near east, about 3, 500 bc, it was discovered that by combining copper and tin, a superior metal could be made, an alloy called bronze. this represented a major technological shift known as the bronze age. the extraction of iron from its ore into a workable metal is much more difficult than for copper or tin. the process appears to have been invented by the hittites in about 1200 bc, beginning the iron age. the secret of extracting and working iron was a key factor in the success of the philistines. historical developments in ferrous metallurgy can be found in a wide variety of past cultures and civilizations. this includes the ancient and medieval kingdoms and empires of the middle east and near east, ancient iran, ancient egypt, ancient nubia, and anatolia in present - day turkey, ancient nok, carthage, the celts, greeks and romans of ancient europe, medieval europe, ancient and medieval china, ancient and to be separated conceptually from geology and crop production and treated as a whole. as a founding father of soil science, fallou has primacy in time. fallou was working on the origins of soil before dokuchaev was born ; however dokuchaev ' s work was more extensive and is considered to be the more significant to modern soil theory than fallou ' s. previously, soil had been considered a product of chemical transformations of rocks, a dead substrate from which plants derive nutritious elements. soil and bedrock were in fact equated. dokuchaev considers the soil as a natural body having its own genesis and its own history of development, a body with complex and multiform processes taking place within it. the soil is considered as different from bedrock. the latter becomes soil under the influence of a series of soil - formation factors ( climate, vegetation, country, relief and age ). according to him, soil should be called the " daily " or outward horizons of rocks regardless of the type ; they are changed naturally by the common effect of water, air and various kinds of living and dead organisms. a 1914 encyclopedic definition : " the different forms of earth on the surface of the rocks, formed by the breaking down or weathering of rocks ". serves to illustrate the historic view of soil which persisted from the 19th century. dokuchaev ' s late 19th century soil concept developed in the 20th century to one of soil as earthy material that has been altered by living processes. a corollary concept is that soil without a living component is simply a part of earth ' s outer layer. further refinement of the soil concept is occurring in view of an appreciation of energy transport and transformation within soil. the term is popularly applied to the material on the surface of the earth ' s moon and mars, a usage acceptable within a portion of the scientific community. accurate to this modern understanding of soil is nikiforoff ' s 1959 definition of soil as the " excited skin of the sub aerial part of the earth ' s crust ". = = areas of practice = = academically, soil scientists tend to be drawn to one of five areas of specialization : microbiology, pedology, edaphology, physics, or chemistry. yet the work specifics are very much dictated by the challenges facing our civilization ' s desire to sustain the land that supports it, and the distinctions between the sub - disciplines of soil science often blur in the process. soil science professionals commonly stay current the fundamental constants could not influence different elements uniformly, and a comparison between each of the elements ' resulting unique chronological timescales would then give inconsistent time estimates. in refutation of young earth claims of inconstant decay rates affecting the reliability of radiometric dating, roger c. wiens, a physicist specializing in isotope dating states : there are only three quite technical instances where a half - life changes, and these do not affect the dating methods : " only one technical exception occurs under terrestrial conditions, and this is not for an isotope used for dating.... the artificially - produced isotope, beryllium - 7 has been shown to change by up to 1. 5 %, depending on its chemical environment.... heavier atoms are even less subject to these minute changes, so the dates of rocks made by electron - capture decays would only be off by at most a few hundredths of a percent. " "... another case is material inside of stars, which is in a plasma state where electrons are not bound to atoms. in the extremely hot stellar environment, a completely different kind of decay can occur. ' bound - state beta decay ' occurs when the nucleus emits an electron into a bound electronic state close to the nucleus.... all normal matter, such as everything on earth, the moon, meteorites, etc. has electrons in normal positions, so these instances never apply to rocks, or anything colder than several hundred thousand degrees. " " the last case also involves very fast - moving matter. it has been demonstrated by atomic clocks in very fast spacecraft. these atomic clocks slow down very slightly ( only a second or so per year ) as predicted by einstein ' s theory of relativity. no rocks in our solar system are going fast enough to make a noticeable change in their dates. " = = = = radiohaloes = = = = in the 1970s, young earth creationist robert v. gentry proposed that radiohaloes in certain granites represented evidence for the earth being created instantaneously rather than gradually. this idea has been criticized by physicists and geologists on many grounds including that the rocks gentry studied were not primordial and that the radionuclides in question need not have been in the rocks initially. thomas a. baillieul, a geologist and retired senior environmental scientist with the united states department of energy, disputed gentry ' s claims in an article entitled, " ' polonium haloes ' refuted : a review of ' radioactive halos in a radio the luminescence of 3 speleothem samples from the acquafredda karst system and 1 from the novella cave ( gessi bolognesi natural park, italy ) has been recorded using excitation by impulse xe - lamp. all these carbonate speleothems are believed to be formed only from active co2 from the air, because the bedrock of the cave consist of gypsum and does not contain carbonates. the obtained photos of luminescence record the climate changes during the speleothem growth. u / th and 14c dating proved that studied speleothems started to grow since about 5, 000 years ago. the detailed analyses of the luminescence records is still in progress. Question: Long-term storage of what element occurs when matter from living organisms is buried deep underground and becomes fossilized? A) oxygen B) Nitrogen C) hydrogen D) carbon	D) carbon
Context: the cross section of elastic electron - proton scattering taking place in an electron gas is calculated within the closed time path method. it is found to be the sum of two terms, one being the expression in the vacuum except that it involves dressing due to the electron gas. the other term is due to the scattering particles - electron gas entanglement. this term dominates the usual one when the exchange energy is in the vicinity of the fermi energy. furthermore it makes the trajectories of the colliding particles more consistent and the collision more irreversible, rendering the scattering more classical in this regime. ##hography is quite small, large area patterns must be created by stitching together the small fields. ion track technology is a deep cutting tool with a resolution limit around 8 nm applicable to radiation resistant minerals, glasses and polymers. it is capable of generating holes in thin films without any development process. structural depth can be defined either by ion range or by material thickness. aspect ratios up to several 104 can be reached. the technique can shape and texture materials at a defined inclination angle. random pattern, single - ion track structures and an aimed pattern consisting of individual single tracks can be generated. x - ray lithography is a process used in the electronic industry to selectively remove parts of a thin film. it uses x - rays to transfer a geometric pattern from a mask to a light - sensitive chemical photoresist, or simply " resist ", on the substrate. a series of chemical treatments then engraves the produced pattern into the material underneath the photoresist. diamond patterning is a method of forming diamond mems. it is achieved by the lithographic application of diamond films to a substrate such as silicon. the patterns can be formed by selective deposition through a silicon dioxide mask, or by deposition followed by micromachining or focused ion beam milling. = = = etching processes = = = there are two basic categories of etching processes : wet etching and dry etching. in the former, the material is dissolved when immersed in a chemical solution. in the latter, the material is sputtered or dissolved using reactive ions or a vapor phase etchant. = = = = wet etching = = = = wet chemical etching consists of the selective removal of material by dipping a substrate into a solution that dissolves it. the chemical nature of this etching process provides good selectivity, which means the etching rate of the target material is considerably higher than the mask material if selected carefully. wet etching can be performed using either isotropic wet etchants or anisotropic wet etchants. isotropic wet etchant etch in all directions of the crystalline silicon at approximately equal rates. anisotropic wet etchants preferably etch along certain crystal planes at faster rates than other planes, thereby allowing more complicated 3 - d microstructures to be implemented. wet anisotropic etchants are often used in conjunction with boron etch stops wherein the surface of the silicon is heavily doped with boron resulting in a silicon material layer that is electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the ability of cells to receive, process, and transmit signals with its environment and with itself. signals can be non - chemical such as light, electrical impulses, and heat, or chemical signals ( or ligands ) that interact with receptors, which can be found embedded in the cell membrane of another cell or located deep inside a cell. there are generally four types of chemical signals : autocrine, paracrine, juxtacrine, and hormones. in autocrine signaling, the ligand affects the same cell that releases it. tumor cells, for example, can reproduce uncontrollably because they release signals that initiate their own self - division. in paracrine signaling, the ligand diffuses to nearby cells and affects them. for example, brain cells called neurons release ligands called neurotransmitters that diffuse across a synaptic cleft to bind with a receptor on an adjacent cell such as another neuron or muscle cell. in juxtacrine signaling, there is direct contact between the signaling and responding cells. finally, hormones are ligands that travel through the circulatory systems of animals or vascular systems of plants to reach their target cells. once a ligand binds with a receptor, it can influence the behavior of another cell, depending on the type of receptor. for instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. other types of receptors include protein kinase receptors ( e. g., receptor for the hormone insulin ) and g protein - coupled receptors. activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and the paper erroneously assumed that the normal carriers giving rise to the backflow could be either electrons or holes. an electron inside liquid helium forms a bubble of 17 \ aa in radius. in an external magnetic field, the two - level system of a spin 1 / 2 electron is ideal for the implementation of a qubit for quantum computing. the electron spin is well isolated from other thermal reservoirs so that the qubit should have very long coherence time. by confining a chain of single electron bubbles in a linear rf quadrupole trap, a multi - bit quantum register can be implemented. all spins in the register can be initialized to the ground state either by establishing thermal equilibrium at a temperature around 0. 1 k and at a magnetic field of 1 t or by sorting the bubbles to be loaded into the trap with magnetic separation. schemes are designed to address individual spins and to do two - qubit cnot operations between the neighboring spins. the final readout can be carried out through a measurement similar to the stern - gerlach experiment. regge - pole calculated low - energy electron elastic total cross sections ( tcss ) for complex heavy atoms and fullerene molecules are characterized generally by ground, metastable, and excited negative - ion formation, shape resonances and ramsauer - townsend minima. here the extracted anionic binding energies ( bes ) from the tcss of various atoms and fullerenes are used to highlight the ambiguous meaning of some current electron affinities ( eas ) of heavy complex atomic systems. the crucial question is : does the ea correspond to the be of the attached electron in the ground or excited state of the formed anion during the collision? the radiation on the material is transferred to the material exposed, as the properties of the exposed and unexposed regions differs. this exposed region can then be removed or treated providing a mask for the underlying substrate. photolithography is typically used with metal or other thin film deposition, wet and dry etching. sometimes, photolithography is used to create structure without any kind of post etching. one example is su8 based lens where su8 based square blocks are generated. then the photoresist is melted to form a semi - sphere which acts as a lens. electron beam lithography ( often abbreviated as e - beam lithography ) is the practice of scanning a beam of electrons in a patterned fashion across a surface covered with a film ( called the resist ), ( " exposing " the resist ) and of selectively removing either exposed or non - exposed regions of the resist ( " developing " ). the purpose, as with photolithography, is to create very small structures in the resist that can subsequently be transferred to the substrate material, often by etching. it was developed for manufacturing integrated circuits, and is also used for creating nanotechnology architectures. the primary advantage of electron beam lithography is that it is one of the ways to beat the diffraction limit of light and make features in the nanometer range. this form of maskless lithography has found wide usage in photomask - making used in photolithography, low - volume production of semiconductor components, and research & development. the key limitation of electron beam lithography is throughput, i. e., the very long time it takes to expose an entire silicon wafer or glass substrate. a long exposure time leaves the user vulnerable to beam drift or instability which may occur during the exposure. also, the turn - around time for reworking or re - design is lengthened unnecessarily if the pattern is not being changed the second time. it is known that focused - ion beam lithography has the capability of writing extremely fine lines ( less than 50 nm line and space has been achieved ) without proximity effect. however, because the writing field in ion - beam lithography is quite small, large area patterns must be created by stitching together the small fields. ion track technology is a deep cutting tool with a resolution limit around 8 nm applicable to radiation resistant minerals, glasses and polymers. it is capable of generating holes in thin films without any development process. structural depth can be defined are continuous lines used to depict edges directly visible from a particular angle. hidden – are short - dashed lines that may be used to represent edges that are not directly visible. center – are alternately long - and short - dashed lines that may be used to represent the axes of circular features. cutting plane – are thin, medium - dashed lines, or thick alternately long - and double short - dashed that may be used to define sections for section views. section – are thin lines in a pattern ( pattern determined by the material being " cut " or " sectioned " ) used to indicate surfaces in section views resulting from " cutting ". section lines are commonly referred to as " cross - hatching ". phantom – ( not shown ) are alternately long - and double short - dashed thin lines used to represent a feature or component that is not part of the specified part or assembly. e. g. billet ends that may be used for testing, or the machined product that is the focus of a tooling drawing. lines can also be classified by a letter classification in which each line is given a letter. type a lines show the outline of the feature of an object. they are the thickest lines on a drawing and done with a pencil softer than hb. type b lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h the connection between the quantum frequency of radiation by the transition of the electron from orbit n to orbit k and frequencies of circling of electron in these orbits for the atom of hydrogen is determined. - dashed lines, or thick alternately long - and double short - dashed that may be used to define sections for section views. section – are thin lines in a pattern ( pattern determined by the material being " cut " or " sectioned " ) used to indicate surfaces in section views resulting from " cutting ". section lines are commonly referred to as " cross - hatching ". phantom – ( not shown ) are alternately long - and double short - dashed thin lines used to represent a feature or component that is not part of the specified part or assembly. e. g. billet ends that may be used for testing, or the machined product that is the focus of a tooling drawing. lines can also be classified by a letter classification in which each line is given a letter. type a lines show the outline of the feature of an object. they are the thickest lines on a drawing and done with a pencil softer than hb. type b lines are dimension lines and are used for dimensioning, projecting, extending, or leaders. a harder pencil should be used, such as a 2h pencil. type c lines are used for breaks when the whole object is not shown. these are freehand drawn and only for short breaks. 2h pencil type d lines are similar to type c, except these are zigzagged and only for longer breaks. 2h pencil type e lines indicate hidden outlines of internal features of an object. these are dotted lines. 2h pencil type f lines are type e lines, except these are used for drawings in electrotechnology. 2h pencil type g lines are used for centre lines. these are dotted lines, but a long line of 10 – 20 mm, then a 1 mm gap, then a small line of 2 mm. 2h pencil type h lines are the same as type g, except that every second long line is thicker. these indicate the cutting plane of an object. 2h pencil type k lines indicate the alternate positions of an object and the line taken by that object. these are drawn with a long line of 10 – 20 mm, then a small gap, then a small line of 2 mm, then a gap, then another small line. 2h pencil. = = = multiple views and projections = = = in most cases, a single view is not sufficient to show all necessary features, and several views are used. types of views include the following : = = = = multiview projection = = = = a multiview projection is a type of orthographic projection Question: Electron configurations are a shorthand method of indicating what subshells electrons occupy in these? A) molecules B) atoms C) solutions D) acids	B) atoms
Context: pigment chlorophyll a. chlorophyll a ( as well as its plant and green algal - specific cousin chlorophyll b ) absorbs light in the blue - violet and orange / red parts of the spectrum while reflecting and transmitting the green light that we see as the characteristic colour of these organisms. the energy in the red and blue light that these pigments absorb is used by chloroplasts to make energy - rich carbon compounds from carbon dioxide and water by oxygenic photosynthesis, a process that generates molecular oxygen ( o2 ) as a by - product. the light energy captured by chlorophyll a is initially in the form of electrons ( and later a proton gradient ) that is used to make molecules of atp and nadph which temporarily store and transport energy. their energy is used in the light - independent reactions of the calvin cycle by the enzyme rubisco to produce molecules of the 3 - carbon sugar glyceraldehyde 3 - phosphate ( g3p ). glyceraldehyde 3 - phosphate is the first product of photosynthesis and the raw material from which glucose and almost all other organic molecules of biological origin are synthesised. some of the glucose is converted to starch which is stored in the chloroplast. starch is the characteristic energy store of most land plants and algae, while inulin, a polymer of fructose is used for the same purpose in the sunflower family asteraceae. some of the glucose is converted to sucrose ( common table sugar ) for export to the rest of the plant. unlike in animals ( which lack chloroplasts ), plants and their eukaryote relatives have delegated many biochemical roles to their chloroplasts, including synthesising all their fatty acids, and most amino acids. the fatty acids that chloroplasts make are used for many things, such as providing material to build cell membranes out of and making the polymer cutin which is found in the plant cuticle that protects land plants from drying out. plants synthesise a number of unique polymers like the polysaccharide molecules cellulose, pectin and xyloglucan from which the land plant cell wall is constructed. vascular land plants make lignin, a polymer used to strengthen the secondary cell walls of xylem tracheids and vessels to keep them from collapsing when a plant sucks water through them under water stress. lignin if stimulated emission could be turned off then only uncorrelated photons would be emitted from black bodies and the photon counting statistics would be poissonian. through the process of stimulated emission, some fraction of the photons emitted from a black body are correlated and thus emitted in clusters. this photon clustering can be calculated by semi - classical means. the corresponding results are in agreement with quantum theory. nanodust, which undergoes stochastic heating by single starlight photons in the interstellar medium, ranges from angstrom - sized large molecules containing tens to thousands of atoms ( e. g. polycyclic aromatic hydrocarbon molecules ) to grains of a couple tens of nanometers. the presence of nanograins in astrophysical environments has been revealed by a variety of interstellar phenomena : the optical luminescence, the near - and mid - infrared emission, the galactic foreground microwave emission, and the ultraviolet extinction which are ubiquitously seen in the interstellar medium of the milky way and beyond. nanograins ( e. g. nanodiamonds ) have also been identified as presolar in primitive meteorites based on their isotopically anomalous composition. considering the very processes that lead to the detection of nanodust in the ism for the nanodust in the solar system shows that the observation of solar system nanodust by these processes is less likely. necessary and sufficient conditions for a term to apply to an object. for example : " a platonic solid is a convex, regular polyhedron in three - dimensional euclidean space. " an extensional definition instead lists all objects where the term applies. for example : " a platonic solid is one of the following : tetrahedron, cube, octahedron, dodecahedron, or icosahedron. " in logic, the extension of a predicate is the set of all objects for which the predicate is true. further, the logical principle of extensionality judges two objects to objects to be equal if they satisfy the same external properties. since, by the axiom, two sets are defined to be equal if they satisfy membership, sets are extentional. jose ferreiros credits richard dedekind for being the first to explicitly state the principle, although he does not assert it as a definition : it very frequently happens that different things a, b, c... considered for any reason under a common point of view, are collected together in the mind, and one then says that they form a system s ; one calls the things a, b, c... the elements of the system s, they are contained in s ; conversely, s consists of these elements. such a system s ( or a collection, a manifold, a totality ), as an object of our thought, is likewise a thing ; it is completely determined when, for every thing, it is determined whether it is an element of s or not. = = = background = = = around the turn of the 20th century, mathematics faced several paradoxes and counter - intuitive results. for example, russell ' s paradox showed a contradiction of naive set theory, it was shown that the parallel postulate cannot be proved, the existence of mathematical objects that cannot be computed or explicitly described, and the existence of theorems of arithmetic that cannot be proved with peano arithmetic. the result was a foundational crisis of mathematics. the resolution of this crisis involved the rise of a new mathematical discipline called mathematical logic, which studies formal logic within mathematics. subsequent discoveries in the 20th century then stabilized the foundations of mathematics into a coherent framework valid for all mathematics. this framework is based on a systematic use of axiomatic method and on set theory, specifically zermelo – fraenkel set theory, developed by ernst zermelo and abraham fraenkel. this set theory ( and set theory in general ) is now considered the most common foundation of mathematics ( pvc ), polystyrene, nylons, polyesters, acrylics, polyurethanes, and polycarbonates. rubbers include natural rubber, styrene - butadiene rubber, chloroprene, and butadiene rubber. plastics are generally classified as commodity, specialty and engineering plastics. polyvinyl chloride ( pvc ) is widely used, inexpensive, and annual production quantities are large. it lends itself to a vast array of applications, from artificial leather to electrical insulation and cabling, packaging, and containers. its fabrication and processing are simple and well - established. the versatility of pvc is due to the wide range of plasticisers and other additives that it accepts. the term " additives " in polymer science refers to the chemicals and compounds added to the polymer base to modify its material properties. polycarbonate would be normally considered an engineering plastic ( other examples include peek, abs ). such plastics are valued for their superior strengths and other special material properties. they are usually not used for disposable applications, unlike commodity plastics. specialty plastics are materials with unique characteristics, such as ultra - high strength, electrical conductivity, electro - fluorescence, high thermal stability, etc. the dividing lines between the various types of plastics is not based on material but rather on their properties and applications. for example, polyethylene ( pe ) is a cheap, low friction polymer commonly used to make disposable bags for shopping and trash, and is considered a commodity plastic, whereas medium - density polyethylene ( mdpe ) is used for underground gas and water pipes, and another variety called ultra - high - molecular - weight polyethylene ( uhmwpe ) is an engineering plastic which is used extensively as the glide rails for industrial equipment and the low - friction socket in implanted hip joints. = = = metal alloys = = = the alloys of iron ( steel, stainless steel, cast iron, tool steel, alloy steels ) make up the largest proportion of metals today both by quantity and commercial value. iron alloyed with various proportions of carbon gives low, mid and high carbon steels. an iron - carbon alloy is only considered steel if the carbon level is between 0. 01 % and 2. 00 % by weight. for steels, the hardness and tensile strength of the steel is related to the amount of carbon present, with increasing carbon levels also leading to lower ductility and toughness. heat treatment and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids are polymers of nucleotides. their function is to store, transmit, and express hereditary information. = = cells = = cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, and that all cells arise from preexisting cells through cell division. most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell , specialty and engineering plastics. polyvinyl chloride ( pvc ) is widely used, inexpensive, and annual production quantities are large. it lends itself to a vast array of applications, from artificial leather to electrical insulation and cabling, packaging, and containers. its fabrication and processing are simple and well - established. the versatility of pvc is due to the wide range of plasticisers and other additives that it accepts. the term " additives " in polymer science refers to the chemicals and compounds added to the polymer base to modify its material properties. polycarbonate would be normally considered an engineering plastic ( other examples include peek, abs ). such plastics are valued for their superior strengths and other special material properties. they are usually not used for disposable applications, unlike commodity plastics. specialty plastics are materials with unique characteristics, such as ultra - high strength, electrical conductivity, electro - fluorescence, high thermal stability, etc. the dividing lines between the various types of plastics is not based on material but rather on their properties and applications. for example, polyethylene ( pe ) is a cheap, low friction polymer commonly used to make disposable bags for shopping and trash, and is considered a commodity plastic, whereas medium - density polyethylene ( mdpe ) is used for underground gas and water pipes, and another variety called ultra - high - molecular - weight polyethylene ( uhmwpe ) is an engineering plastic which is used extensively as the glide rails for industrial equipment and the low - friction socket in implanted hip joints. = = = metal alloys = = = the alloys of iron ( steel, stainless steel, cast iron, tool steel, alloy steels ) make up the largest proportion of metals today both by quantity and commercial value. iron alloyed with various proportions of carbon gives low, mid and high carbon steels. an iron - carbon alloy is only considered steel if the carbon level is between 0. 01 % and 2. 00 % by weight. for steels, the hardness and tensile strength of the steel is related to the amount of carbon present, with increasing carbon levels also leading to lower ductility and toughness. heat treatment processes such as quenching and tempering can significantly change these properties, however. in contrast, certain metal alloys exhibit unique properties where their size and density remain unchanged across a range of temperatures. cast iron is defined as an iron – carbon alloy with more than 2. 00 %, but less than 6. 67 % the status of the theory of color confinemnt is discussed. 13, 1960 ; and china component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. a radiological weapon is a type of nuclear weapon designed to distribute hazardous nuclear material in enemy areas. such a weapon would not have the explosive capability of a fission or fusion bomb, but would kill many people and contaminate a large area. a radiological weapon has never been deployed. while considered useless by a conventional military, such a weapon raises concerns over nuclear terrorism. there have been over 2, 000 nuclear tests conducted since 1945. in 1963, all nuclear and many non - nuclear states signed the limited test ban treaty, pledging to refrain from testing nuclear weapons in the atmosphere, underwater, or in outer space. the treaty permitted underground nuclear testing. france continued atmospheric testing until 1974, while china continued up until 1980. the last underground test by the united states was in 1992, the soviet union in 1990, the united kingdom in 1991, and both france and china continued testing until 1996. after signing the comprehensive test ban treaty in 1996 ( which had as of 2011 not entered into force ), all of these states have pledged to discontinue all nuclear testing. non - signatories india and pakistan last tested nuclear weapons in 1998. nuclear weapons are the most destructive weapons known - the archetypal weapons of mass destruction. throughout the cold war, the opposing powers had huge nuclear arsenals, sufficient to kill hundreds of millions of people. generations of people grew up under the shadow of nuclear devastation, portrayed in films such as dr. strangelove and the atomic cafe. however, the tremendous energy release in the detonation of a nuclear weapon also suggested the possibility of a new energy source. = = civilian uses = = = = = nuclear power = = = nuclear power is a type of nuclear technology involving the controlled use of nuclear fission to release energy for work including propulsion, heat, and the generation of electricity. nuclear energy is produced by a controlled nuclear chain reaction which creates heat — and which is used to boil water, produce steam, and drive a steam turbine. the turbine is used to generate electricity and / or to do mechanical work. currently nuclear power provides approximately 15. 7 % of the world ' s electricity ( in 2004 ) and is used to propel aircraft carriers, icebreakers and submarines ( so far economics and fears in some ports have prevented the use of nuclear power in transport ships ). all nuclear power plants use fission. no man - made fusion reaction reflectometer ), which takes measurements in the visible region ( and a little beyond ) of a given color sample. if the custom of taking readings at 10 nanometer increments is followed, the visible light range of 400 – 700 nm will yield 31 readings. these readings are typically used to draw the sample ' s spectral reflectance curve ( how much it reflects, as a function of wavelength ) — the most accurate data that can be provided regarding its characteristics. the readings by themselves are typically not as useful as their tristimulus values, which can be converted into chromaticity co - ordinates and manipulated through color space transformations. for this purpose, a spectrocolorimeter may be used. a spectrocolorimeter is simply a spectrophotometer that can estimate tristimulus values by numerical integration ( of the color matching functions ' inner product with the illuminant ' s spectral power distribution ). one benefit of spectrocolorimeters over tristimulus colorimeters is that they do not have optical filters, which are subject to manufacturing variance, and have a fixed spectral transmittance curve — until they age. on the other hand, tristimulus colorimeters are purpose - built, cheaper, and easier to use. the cie ( international commission on illumination ) recommends using measurement intervals under 5 nm, even for smooth spectra. sparser measurements fail to accurately characterize spiky emission spectra, such as that of the red phosphor of a crt display, depicted aside. = = = color temperature meter = = = photographers and cinematographers use information provided by these meters to decide what color balancing should be done to make different light sources appear to have the same color temperature. if the user enters the reference color temperature, the meter can calculate the mired difference between the measurement and the reference, enabling the user to choose a corrective color gel or photographic filter with the closest mired factor. internally the meter is typically a silicon photodiode tristimulus colorimeter. the correlated color temperature can be calculated from the tristimulus values by first calculating the chromaticity co - ordinates in the cie 1960 color space, then finding the closest point on the planckian locus. = = see also = = color science photometry radiometry = = references = = = = further reading = = schanda, janos d. ( 1997 ). " colorimetry " ( pdf ). in casimer decusatis ( ed. ). handbook Question: Light emitted by atoms is polychromatic—containing more than one of these? A) wavelength B) filter C) gravity D) weight	A) wavelength
Context: blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with support matrices for tissue engineering applications. an adequate environment for promoting cell growth, differentiation, and integration with the existing tissue is a critical factor for cell - based building blocks. manipulation of any of these cell processes create alternative avenues for the development of new tissue ( e. g., cell reprogramming - somatic cells, vascularization ). = = = isolation = = = techniques for cell isolation depend on the cell source. centrifugation and apheresis are techniques used for extracting cells from biofluids ( e. g., blood ). whereas digestion processes, typically using enzymes to remove the extra required. for example, certain cells respond to changes in oxygen tension as part of their normal development, such as chondrocytes, which must adapt to low oxygen conditions or hypoxia during skeletal development. others, such as endothelial cells, respond to shear stress from fluid flow, which is encountered in blood vessels. mechanical stimuli, such as pressure pulses seem to be beneficial to all kind of cardiovascular tissue such as heart valves, blood vessels or pericardium. = = = bioreactors = = = in tissue engineering, a bioreactor is a device that attempts to simulate a physiological environment in order to promote cell or tissue growth in vitro. a physiological environment can consist of many different parameters such as temperature, pressure, oxygen or carbon dioxide concentration, or osmolality of fluid environment, and it can extend to all kinds of biological, chemical or mechanical stimuli. therefore, there are systems that may include the application of forces such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the this scaffold and cells were placed in a bioreactor, where it matured to become a partially or fully transplantable organ. the work was called a " landmark ". the lab first stripped the cells away from a rat heart ( a process called " decellularization " ) and then injected rat stem cells into the decellularized rat heart. tissue - engineered blood vessels : blood vessels that have been grown in a lab and can be used to repair damaged blood vessels without eliciting an immune response. tissue engineered blood vessels have been developed by many different approaches. they could be implanted as pre - seeded cellularized blood vessels, as acellular vascular grafts made with decellularized vessels or synthetic vascular grafts. artificial skin constructed from human skin cells embedded in a hydrogel, such as in the case of bio - printed constructs for battlefield burn repairs. artificial bone marrow : bone marrow cultured in vitro to be transplanted serves as a " just cells " approach to tissue engineering. tissue engineered bone : a structural matrix can be composed of metals such as titanium, polymers of varying degradation rates, or certain types of ceramics. materials are often chosen to recruit osteoblasts to aid in reforming the bone and returning biological function. various types of cells can be added directly into the matrix to expedite the process. laboratory - grown penis : decellularized scaffolds of rabbit penises were recellularised with smooth muscle and endothelial cells. the organ was then transplanted to live rabbits and functioned comparably to the native organ, suggesting potential as treatment for genital trauma. oral mucosa tissue engineering uses a cells and scaffold approach to replicate the 3 dimensional structure and function of oral mucosa. = = cells as building blocks = = cells are one of the main components for the success of tissue engineering approaches. tissue engineering uses cells as strategies for creation / replacement of new tissue. examples include fibroblasts used for skin repair or renewal, chondrocytes used for cartilage repair ( maci – fda approved product ), and hepatocytes used in liver support systems cells can be used alone or with support matrices for tissue engineering applications. an adequate environment for promoting cell growth, differentiation, and integration with the existing tissue is a critical factor for cell - based building blocks. manipulation of any of these cell processes create alternative avenues for the development of new tissue ( e. g., cell reprogramming - somatic managing blood lipid levels is important for the treatment and prevention of diabetes, cardiovascular disease, and obesity. an easy - to - use, portable lipid blood test will accelerate more frequent testing by patients and at - risk populations. we used smartphone systems that are already familiar to many people. because smartphone systems can be carried around everywhere, blood can be measured easily and frequently. we compared the results of lipid tests with those of existing clinical diagnostic laboratory methods. we found that smartphone - based point - of - care lipid blood tests are as accurate as hospital - grade laboratory tests. our system will be useful for those who need to manage blood lipid levels to motivate them to track and control their behavior. exchanges between the blood compartment and the surrounding tissues require a tight regulation by the endothelial barrier. recent reports inferred that ve - cadherin, an endothelial specific cell - cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. indeed, a growing number of permeability inducing factors ( pifs ) was shown to elicit signaling mechanisms culminating in ve - cadherin destabilization and global alteration of the junctional architecture. conversely, anti - pifs protect from ve - cadherin disruption and enhance cell cohesion. these findings provide evidence on how endothelial cell - cell junctions impact the vascular network, and change our perception about normal and aberrant angiogenesis. , characterizing organs as predominantly yin or yang, and understood the relationship between the pulse, the heart, and the flow of blood in the body centuries before it became accepted in the west. little evidence survives of how ancient indian cultures around the indus river understood nature, but some of their perspectives may be reflected in the vedas, a set of sacred hindu texts. they reveal a conception of the universe as ever - expanding and constantly being recycled and reformed. surgeons in the ayurvedic tradition saw health and illness as a combination of three humors : wind, bile and phlegm. a healthy life resulted from a balance among these humors. in ayurvedic thought, the body consisted of five elements : earth, water, fire, wind, and space. ayurvedic surgeons performed complex surgeries and developed a detailed understanding of human anatomy. pre - socratic philosophers in ancient greek culture brought natural philosophy a step closer to direct inquiry about cause and effect in nature between 600 and 400 bc. however, an element of magic and mythology remained. natural phenomena such as earthquakes and eclipses were explained increasingly in the context of nature itself instead of being attributed to angry gods. thales of miletus, an early philosopher who lived from 625 to 546 bc, explained earthquakes by theorizing that the world floated on water and that water was the fundamental element in nature. in the 5th century bc, leucippus was an early exponent of atomism, the idea that the world is made up of fundamental indivisible particles. pythagoras applied greek innovations in mathematics to astronomy and suggested that the earth was spherical. = = = aristotelian natural philosophy ( 400 bc – 1100 ad ) = = = later socratic and platonic thought focused on ethics, morals, and art and did not attempt an investigation of the physical world ; plato criticized pre - socratic thinkers as materialists and anti - religionists. aristotle, however, a student of plato who lived from 384 to 322 bc, paid closer attention to the natural world in his philosophy. in his history of animals, he described the inner workings of 110 species, including the stingray, catfish and bee. he investigated chick embryos by breaking open eggs and observing them at various stages of development. aristotle ' s works were influential through the 16th century, and he is considered to be the father of biology for his pioneering work in that science. he also presented philosophies about physics, nature, and astronomy using the flow of fluids at branching junctions plays important kinematic and dynamic roles in most biological and industrial flow systems. the present paper highlights some key issues related to the flow of fluids at these junctions with special emphasis on the biological flow networks particularly blood transportation vasculature. such as electromagnetic forces, mechanical pressures, or fluid pressures to the tissue. these systems can be two - or three - dimensional setups. bioreactors can be used in both academic and industry applications. general - use and application - specific bioreactors are also commercially available, which may provide static chemical stimulation or a combination of chemical and mechanical stimulation. cell proliferation and differentiation are largely influenced by mechanical and biochemical cues in the surrounding extracellular matrix environment. bioreactors are typically developed to replicate the specific physiological environment of the tissue being grown ( e. g., flex and fluid shearing for heart tissue growth ). this can allow specialized cell lines to thrive in cultures replicating their native environments, but it also makes bioreactors attractive tools for culturing stem cells. a successful stem - cell - based bioreactor is effective at expanding stem cells with uniform properties and / or promoting controlled, reproducible differentiation into selected mature cell types. there are a variety of bioreactors designed for 3d cell cultures. there are small plastic cylindrical chambers, as well as glass chambers, with regulated internal humidity and moisture specifically engineered for the purpose of growing cells in three dimensions. the bioreactor uses bioactive synthetic materials such as polyethylene terephthalate membranes to surround the spheroid cells in an environment that maintains high levels of nutrients. they are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100 % humidity throughout. this humidity is important to achieve maximum cell growth and function. the bioreactor chamber is part of a larger device that rotates to ensure equal cell growth in each direction across three dimensions. quinxell technologies now under quintech life sciences from singapore has developed a bioreactor known as the tisxell biaxial bioreactor which is specially designed for the purpose of tissue engineering. it is the first bioreactor in the world to have a spherical glass chamber with biaxial rotation ; specifically to mimic the rotation of the fetus in the womb ; which provides a conducive environment for the growth of tissues. multiple forms of mechanical stimulation have also been combined into a single bioreactor. using gene expression analysis, one academic study found that applying a combination of cyclic strain and ultrasound stimulation to pre - osteoblast cells in a bioreactor accelerated matrix maturation and differentiation. the technology of this combined stimulation bioreactor could be used to grow bone cells more quickly and effectively as subjective artistic creations, artistic paintings carry emotion of their creators. emotions expressed in paintings and emotion aroused in spectators by paintings are two kinds of emotions that scholars have paid attention to. traditional studies on emotions expressed by paintings are mainly conducted from qualitative perspectives, with neither quantitative output on the emotional values of a painting, nor exploration of trends in the expression of emotion in art history. in this research we threat facial expressions in paintings as an artistic characteristics of art history and employ cognitive computation technology to identify the facial emotions in paintings and to investigate the quantitative measures of paintings from three emotion - related aspects : the spatial and temporal patterns of painting emotions in art history, the gender difference on the emotion of paintings and the color preference associated with emotions. we discovered that the emotion of happiness has a growing trend from ancient to modern times in paintings history, and men and women have different facial expressions patterns along time. as for color preference, artists with different culture backgrounds had similar association preferences between colors and emotions. Question: What fatty material inside arteries can restrict blood flow in the artery? A) cholesterol B) marble C) plaque D) collagen	C) plaque
Context: missiles, ships, vehicles, and also to map weather patterns and terrain. a radar set consists of a transmitter and receiver. the transmitter emits a narrow beam of radio waves which is swept around the surrounding space. when the beam strikes a target object, radio waves are reflected back to the receiver. the direction of the beam reveals the object ' s location. since radio waves travel at a constant speed close to the speed of light, by measuring the brief time delay between the outgoing pulse and the received " echo ", the range to the target can be calculated. the targets are often displayed graphically on a map display called a radar screen. doppler radar can measure a moving object ' s velocity, by measuring the change in frequency of the return radio waves due to the doppler effect. radar sets mainly use high frequencies in the microwave bands, because these frequencies create strong reflections from objects the size of vehicles and can be focused into narrow beams with compact antennas. parabolic ( dish ) antennas are widely used. in most radars the transmitting antenna also serves as the receiving antenna ; this is called a monostatic radar. a radar which uses separate transmitting and receiving antennas is called a bistatic radar. airport surveillance radar – in aviation, radar is the main tool of air traffic control. a rotating dish antenna sweeps a vertical fan - shaped beam of microwaves around the airspace and the radar set shows the location of aircraft as " blips " of light on a display called a radar screen. airport radar operates at 2. 7 – 2. 9 ghz in the microwave s band. in large airports the radar image is displayed on multiple screens in an operations room called the tracon ( terminal radar approach control ), where air traffic controllers direct the aircraft by radio to maintain safe aircraft separation. secondary surveillance radar – aircraft carry radar transponders, transceivers which when triggered by the incoming radar signal transmit a return microwave signal. this causes the aircraft to show up more strongly on the radar screen. the radar which triggers the transponder and receives the return beam, usually mounted on top of the primary radar dish, is called the secondary surveillance radar. since radar cannot measure an aircraft ' s altitude with any accuracy, the transponder also transmits back the aircraft ' s altitude measured by its altimeter, and an id number identifying the aircraft, which is displayed on the radar screen. electronic countermeasures ( ecm ) – military defensive electronic systems designed to degrade enemy radar effectiveness, or deceive it the group velocity of light has been measured at eight different wavelengths between 385 nm and 532 nm in the mediterranean sea at a depth of about 2. 2 km with the antares optical beacon systems. a parametrisation of the dependence of the refractive index on wavelength based on the salinity, pressure and temperature of the sea water at the antares site is in good agreement with these measurements. unitary recordings in freely - moving pulse weakly electric fish suggest spike timing encoding of electrosensory signals subsea engineering and the ability to detect, track and destroy submarines ( anti - submarine warfare ) required the parallel development of a host of marine scientific instrumentation and sensors. visible light is not transferred far underwater, so the medium for transmission of data is primarily acoustic. high - frequency sound is used to measure the depth of the ocean, determine the nature of the seafloor, and detect submerged objects. the higher the frequency, the higher the definition of the data that is returned. sound navigation and ranging or sonar was developed during the first world war to detect submarines, and has been greatly refined through to the present day. submarines similarly use sonar equipment to detect and target other submarines and surface ships, and to detect submerged obstacles such as seamounts that pose a navigational obstacle. simple echo - sounders point straight down and can give an accurate reading of ocean depth ( or look up at the underside of sea - ice ). more advanced echo sounders use a fan - shaped beam or sound, or multiple beams to derive highly detailed images of the ocean floor. high power systems can penetrate the soil and seabed rocks to give information about the geology of the seafloor, and are widely used in geophysics for the discovery of hydrocarbons, or for engineering survey. for close - range underwater communications, optical transmission is possible, mainly using blue lasers. these have a high bandwidth compared with acoustic systems, but the range is usually only a few tens of metres, and ideally at night. as well as acoustic communications and navigation, sensors have been developed to measure ocean parameters such as temperature, salinity, oxygen levels and other properties including nitrate levels, levels of trace chemicals and environmental dna. the industry trend has been towards smaller, more accurate and more affordable systems so that they can be purchased and used by university departments and small companies as well as large corporations, research organisations and governments. the sensors and instruments are fitted to autonomous and remotely - operated systems as well as ships, and are enabling these systems to take on tasks that hitherto required an expensive human - crewed platform. manufacture of marine sensors and instruments mainly takes place in asia, europe and north america. products are advertised in specialist journals, and through trade shows such as oceanology international and ocean business which help raise awareness of the products. = = = environmental engineering = = = in every coastal and offshore project, environmental sustainability is an important consideration for the preservation of ocean ecosystems and natural resources. instances in which marine engineers benefit from knowledge of environmental engineering include creation of fisheries, clean it is stronger, then demodulates it, extracting the original modulation signal from the modulated carrier wave. the modulation signal is converted by a transducer back to a human - usable form : an audio signal is converted to sound waves by a loudspeaker or earphones, a video signal is converted to images by a display, while a digital signal is applied to a computer or microprocessor, which interacts with human users. the radio waves from many transmitters pass through the air simultaneously without interfering with each other because each transmitter ' s radio waves oscillate at a different frequency, measured in hertz ( hz ), kilohertz ( khz ), megahertz ( mhz ) or gigahertz ( ghz ). the receiving antenna typically picks up the radio signals of many transmitters. the receiver uses tuned circuits to select the radio signal desired out of all the signals picked up by the antenna and reject the others. a tuned circuit acts like a resonator, similar to a tuning fork. it has a natural resonant frequency at which it oscillates. the resonant frequency of the receiver ' s tuned circuit is adjusted by the user to the frequency of the desired radio station ; this is called tuning. the oscillating radio signal from the desired station causes the tuned circuit to oscillate in sympathy, and it passes the signal on to the rest of the receiver. radio signals at other frequencies are blocked by the tuned circuit and not passed on. = = = bandwidth = = = a modulated radio wave, carrying an information signal, occupies a range of frequencies. the information in a radio signal is usually concentrated in narrow frequency bands called sidebands ( sb ) just above and below the carrier frequency. the width in hertz of the frequency range that the radio signal occupies, the highest frequency minus the lowest frequency, is called its bandwidth ( bw ). for any given signal - to - noise ratio, a given bandwidth can carry the same amount of information regardless of where in the radio frequency spectrum it is located ; bandwidth is a measure of information - carrying capacity. the bandwidth required by a radio transmission depends on the data rate of the information being sent, and the spectral efficiency of the modulation method used ; how much data it can transmit in each unit of bandwidth. different types of information signals carried by radio have different data rates. for example, a television signal has a greater data rate than an audio signal. the radio spectrum, the total range of are combined in the proper order into one bitstream. many other types of modulation are also used. in some types, the carrier wave is suppressed, and only one or both modulation sidebands are transmitted. the modulated carrier is amplified in the transmitter and applied to a transmitting antenna which radiates the energy as radio waves. the radio waves carry the information to the receiver location. at the receiver, the radio wave induces a tiny oscillating voltage in the receiving antenna – a weaker replica of the current in the transmitting antenna. this voltage is applied to the radio receiver, which amplifies the weak radio signal so it is stronger, then demodulates it, extracting the original modulation signal from the modulated carrier wave. the modulation signal is converted by a transducer back to a human - usable form : an audio signal is converted to sound waves by a loudspeaker or earphones, a video signal is converted to images by a display, while a digital signal is applied to a computer or microprocessor, which interacts with human users. the radio waves from many transmitters pass through the air simultaneously without interfering with each other because each transmitter ' s radio waves oscillate at a different frequency, measured in hertz ( hz ), kilohertz ( khz ), megahertz ( mhz ) or gigahertz ( ghz ). the receiving antenna typically picks up the radio signals of many transmitters. the receiver uses tuned circuits to select the radio signal desired out of all the signals picked up by the antenna and reject the others. a tuned circuit acts like a resonator, similar to a tuning fork. it has a natural resonant frequency at which it oscillates. the resonant frequency of the receiver ' s tuned circuit is adjusted by the user to the frequency of the desired radio station ; this is called tuning. the oscillating radio signal from the desired station causes the tuned circuit to oscillate in sympathy, and it passes the signal on to the rest of the receiver. radio signals at other frequencies are blocked by the tuned circuit and not passed on. = = = bandwidth = = = a modulated radio wave, carrying an information signal, occupies a range of frequencies. the information in a radio signal is usually concentrated in narrow frequency bands called sidebands ( sb ) just above and below the carrier frequency. the width in hertz of the frequency range that the radio signal occupies, the highest frequency minus the lowest frequency, beacon transmits two signals simultaneously on different frequencies. a directional antenna transmits a beam of radio waves that rotates like a lighthouse at a fixed rate, 30 times per second. when the directional beam is facing north, an omnidirectional antenna transmits a pulse. by measuring the difference in phase of these two signals, an aircraft can determine its bearing ( or " radial " ) from the station accurately. by taking a bearing on two vor beacons an aircraft can determine its position ( called a " fix " ) to an accuracy of about 90 metres ( 300 ft ). most vor beacons also have a distance measuring capability, called distance measuring equipment ( dme ) ; these are called vor / dme ' s. the aircraft transmits a radio signal to the vor / dme beacon and a transponder transmits a return signal. from the propagation delay between the transmitted and received signal the aircraft can calculate its distance from the beacon. this allows an aircraft to determine its location " fix " from only one vor beacon. since line - of - sight vhf frequencies are used vor beacons have a range of about 200 miles for aircraft at cruising altitude. tacan is a similar military radio beacon system which transmits in 962 – 1213 mhz, and a combined vor and tacan beacon is called a vortac. the number of vor beacons is declining as aviation switches to the rnav system that relies on global positioning system satellite navigation. instrument landing system ( ils ) - a short range radio navigation aid at airports which guides aircraft landing in low visibility conditions. it consists of multiple antennas at the end of each runway that radiate two beams of radio waves along the approach to the runway : the localizer ( 108 to 111. 95 mhz frequency ), which provides horizontal guidance, a heading line to keep the aircraft centered on the runway, and the glideslope ( 329. 15 to 335 mhz ) for vertical guidance, to keep the aircraft descending at the proper rate for a smooth touchdown at the correct point on the runway. each aircraft has a receiver instrument and antenna which receives the beams, with an indicator to tell the pilot whether he is on the correct horizontal and vertical approach. the ils beams are receivable for at least 15 miles, and have a radiated power of 25 watts. ils systems at airports are being replaced by systems that use satellite navigation. non - directional beacon ( ndb ) – legacy fixed radio beacons used before the vo the nervous system. these kinds of tests can be divided into recordings of : ( 1 ) spontaneous or continuously running electrical activity, or ( 2 ) stimulus evoked responses. subspecialties include electroencephalography, electromyography, evoked potential, nerve conduction study and polysomnography. sometimes these tests are performed by techs without a medical degree, but the interpretation of these tests is done by a medical professional. diagnostic radiology is concerned with imaging of the body, e. g. by x - rays, x - ray computed tomography, ultrasonography, and nuclear magnetic resonance tomography. interventional radiologists can access areas in the body under imaging for an intervention or diagnostic sampling. nuclear medicine is concerned with studying human organ systems by administering radiolabelled substances ( radiopharmaceuticals ) to the body, which can then be imaged outside the body by a gamma camera or a pet scanner. each radiopharmaceutical consists of two parts : a tracer that is specific for the function under study ( e. g., neurotransmitter pathway, metabolic pathway, blood flow, or other ), and a radionuclide ( usually either a gamma - emitter or a positron emitter ). there is a degree of overlap between nuclear medicine and radiology, as evidenced by the emergence of combined devices such as the pet / ct scanner. pathology as a medical specialty is the branch of medicine that deals with the study of diseases and the morphologic, physiologic changes produced by them. as a diagnostic specialty, pathology can be considered the basis of modern scientific medical knowledge and plays a large role in evidence - based medicine. many modern molecular tests such as flow cytometry, polymerase chain reaction ( pcr ), immunohistochemistry, cytogenetics, gene rearrangements studies and fluorescent in situ hybridization ( fish ) fall within the territory of pathology. = = = = other major specialties = = = = the following are some major medical specialties that do not directly fit into any of the above - mentioned groups : anesthesiology ( also known as anaesthetics ) : concerned with the perioperative management of the surgical patient. the anesthesiologist ' s role during surgery is to prevent derangement in the vital organs ' ( i. e. brain, heart, kidneys ) functions and postoperative pain. outside of beam reveals the object ' s location. since radio waves travel at a constant speed close to the speed of light, by measuring the brief time delay between the outgoing pulse and the received " echo ", the range to the target can be calculated. the targets are often displayed graphically on a map display called a radar screen. doppler radar can measure a moving object ' s velocity, by measuring the change in frequency of the return radio waves due to the doppler effect. radar sets mainly use high frequencies in the microwave bands, because these frequencies create strong reflections from objects the size of vehicles and can be focused into narrow beams with compact antennas. parabolic ( dish ) antennas are widely used. in most radars the transmitting antenna also serves as the receiving antenna ; this is called a monostatic radar. a radar which uses separate transmitting and receiving antennas is called a bistatic radar. airport surveillance radar – in aviation, radar is the main tool of air traffic control. a rotating dish antenna sweeps a vertical fan - shaped beam of microwaves around the airspace and the radar set shows the location of aircraft as " blips " of light on a display called a radar screen. airport radar operates at 2. 7 – 2. 9 ghz in the microwave s band. in large airports the radar image is displayed on multiple screens in an operations room called the tracon ( terminal radar approach control ), where air traffic controllers direct the aircraft by radio to maintain safe aircraft separation. secondary surveillance radar – aircraft carry radar transponders, transceivers which when triggered by the incoming radar signal transmit a return microwave signal. this causes the aircraft to show up more strongly on the radar screen. the radar which triggers the transponder and receives the return beam, usually mounted on top of the primary radar dish, is called the secondary surveillance radar. since radar cannot measure an aircraft ' s altitude with any accuracy, the transponder also transmits back the aircraft ' s altitude measured by its altimeter, and an id number identifying the aircraft, which is displayed on the radar screen. electronic countermeasures ( ecm ) – military defensive electronic systems designed to degrade enemy radar effectiveness, or deceive it with false information, to prevent enemies from locating local forces. it often consists of powerful microwave transmitters that can mimic enemy radar signals to create false target indications on the enemy radar screens. marine radar – an s or x band radar on ships used to detect nearby ships and obstructions like bridges. a rotating antenna sweeps a vertical even artillery shells to their target, and handheld gps receivers are produced for hikers and the military. radio beacon – a fixed location terrestrial radio transmitter which transmits a continuous radio signal used by aircraft and ships for navigation. the locations of beacons are plotted on navigational maps used by aircraft and ships. vhf omnidirectional range ( vor ) – a worldwide aircraft radio navigation system consisting of fixed ground radio beacons transmitting between 108. 00 and 117. 95 mhz in the very high frequency ( vhf ) band. an automated navigational instrument on the aircraft displays a bearing to a nearby vor transmitter. a vor beacon transmits two signals simultaneously on different frequencies. a directional antenna transmits a beam of radio waves that rotates like a lighthouse at a fixed rate, 30 times per second. when the directional beam is facing north, an omnidirectional antenna transmits a pulse. by measuring the difference in phase of these two signals, an aircraft can determine its bearing ( or " radial " ) from the station accurately. by taking a bearing on two vor beacons an aircraft can determine its position ( called a " fix " ) to an accuracy of about 90 metres ( 300 ft ). most vor beacons also have a distance measuring capability, called distance measuring equipment ( dme ) ; these are called vor / dme ' s. the aircraft transmits a radio signal to the vor / dme beacon and a transponder transmits a return signal. from the propagation delay between the transmitted and received signal the aircraft can calculate its distance from the beacon. this allows an aircraft to determine its location " fix " from only one vor beacon. since line - of - sight vhf frequencies are used vor beacons have a range of about 200 miles for aircraft at cruising altitude. tacan is a similar military radio beacon system which transmits in 962 – 1213 mhz, and a combined vor and tacan beacon is called a vortac. the number of vor beacons is declining as aviation switches to the rnav system that relies on global positioning system satellite navigation. instrument landing system ( ils ) - a short range radio navigation aid at airports which guides aircraft landing in low visibility conditions. it consists of multiple antennas at the end of each runway that radiate two beams of radio waves along the approach to the runway : the localizer ( 108 to 111. 95 mhz frequency ), which provides horizontal guidance, a heading line to keep the aircraft centered on Question: What is used to record seismic waves? A) transmitter B) topometer C) seismograph D) odometer	C) seismograph
Context: the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist pigment chlorophyll a. chlorophyll a ( as well as its plant and green algal - specific cousin chlorophyll b ) absorbs light in the blue - violet and orange / red parts of the spectrum while reflecting and transmitting the green light that we see as the characteristic colour of these organisms. the energy in the red and blue light that these pigments absorb is used by chloroplasts to make energy - rich carbon compounds from carbon dioxide and water by oxygenic photosynthesis, a process that generates molecular oxygen ( o2 ) as a by - product. the light energy captured by chlorophyll a is initially in the form of electrons ( and later a proton gradient ) that is used to make molecules of atp and nadph which temporarily store and transport energy. their energy is used in the light - independent reactions of the calvin cycle by the enzyme rubisco to produce molecules of the 3 - carbon sugar glyceraldehyde 3 - phosphate ( g3p ). glyceraldehyde 3 - phosphate is the first product of photosynthesis and the raw material from which glucose and almost all other organic molecules of biological origin are synthesised. some of the glucose is converted to starch which is stored in the chloroplast. starch is the characteristic energy store of most land plants and algae, while inulin, a polymer of fructose is used for the same purpose in the sunflower family asteraceae. some of the glucose is converted to sucrose ( common table sugar ) for export to the rest of the plant. unlike in animals ( which lack chloroplasts ), plants and their eukaryote relatives have delegated many biochemical roles to their chloroplasts, including synthesising all their fatty acids, and most amino acids. the fatty acids that chloroplasts make are used for many things, such as providing material to build cell membranes out of and making the polymer cutin which is found in the plant cuticle that protects land plants from drying out. plants synthesise a number of unique polymers like the polysaccharide molecules cellulose, pectin and xyloglucan from which the land plant cell wall is constructed. vascular land plants make lignin, a polymer used to strengthen the secondary cell walls of xylem tracheids and vessels to keep them from collapsing when a plant sucks water through them under water stress. lignin of these organisms. the energy in the red and blue light that these pigments absorb is used by chloroplasts to make energy - rich carbon compounds from carbon dioxide and water by oxygenic photosynthesis, a process that generates molecular oxygen ( o2 ) as a by - product. the light energy captured by chlorophyll a is initially in the form of electrons ( and later a proton gradient ) that is used to make molecules of atp and nadph which temporarily store and transport energy. their energy is used in the light - independent reactions of the calvin cycle by the enzyme rubisco to produce molecules of the 3 - carbon sugar glyceraldehyde 3 - phosphate ( g3p ). glyceraldehyde 3 - phosphate is the first product of photosynthesis and the raw material from which glucose and almost all other organic molecules of biological origin are synthesised. some of the glucose is converted to starch which is stored in the chloroplast. starch is the characteristic energy store of most land plants and algae, while inulin, a polymer of fructose is used for the same purpose in the sunflower family asteraceae. some of the glucose is converted to sucrose ( common table sugar ) for export to the rest of the plant. unlike in animals ( which lack chloroplasts ), plants and their eukaryote relatives have delegated many biochemical roles to their chloroplasts, including synthesising all their fatty acids, and most amino acids. the fatty acids that chloroplasts make are used for many things, such as providing material to build cell membranes out of and making the polymer cutin which is found in the plant cuticle that protects land plants from drying out. plants synthesise a number of unique polymers like the polysaccharide molecules cellulose, pectin and xyloglucan from which the land plant cell wall is constructed. vascular land plants make lignin, a polymer used to strengthen the secondary cell walls of xylem tracheids and vessels to keep them from collapsing when a plant sucks water through them under water stress. lignin is also used in other cell types like sclerenchyma fibres that provide structural support for a plant and is a major constituent of wood. sporopollenin is a chemically resistant polymer found in the outer cell walls of spores and pollen of land plants responsible for the survival of early land plant spores and much sunlight the plant receives each day. this can result in adaptive changes in a process known as photomorphogenesis. phytochromes are the photoreceptors in a plant that are sensitive to light. = = plant anatomy and morphology = = plant anatomy is the study of the structure of plant cells and tissues, whereas plant morphology is the study of their external form. all plants are multicellular eukaryotes, their dna stored in nuclei. the characteristic features of plant cells that distinguish them from those of animals and fungi include a primary cell wall composed of the polysaccharides cellulose, hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable of creating cells of the other and producing adventitious shoots or roots. stolons and tubers are examples of shoots that can grow roots. roots that spread out close to the surface, such as those of willows, can produce shoots and ultimately new plants. in the event that one of the systems is lost energy they need to exist. plants, algae and cyanobacteria are the major groups of organisms that carry out photosynthesis, a process that uses the energy of sunlight to convert water and carbon dioxide into sugars that can be used both as a source of chemical energy and of organic molecules that are used in the structural components of cells. as a by - product of photosynthesis, plants release oxygen into the atmosphere, a gas that is required by nearly all living things to carry out cellular respiration. in addition, they are influential in the global carbon and water cycles and plant roots bind and stabilise soils, preventing soil erosion. plants are crucial to the future of human society as they provide food, oxygen, biochemicals, and products for people, as well as creating and preserving soil. historically, all living things were classified as either animals or plants and botany covered the study of all organisms not considered animals. botanists examine both the internal functions and processes within plant organelles, cells, tissues, whole plants, plant populations and plant communities. at each of these levels, a botanist may be concerned with the classification ( taxonomy ), phylogeny and evolution, structure ( anatomy and morphology ), or function ( physiology ) of plant life. the strictest definition of " plant " includes only the " land plants " or embryophytes, which include seed plants ( gymnosperms, including the pines, and flowering plants ) and the free - sporing cryptogams including ferns, clubmosses, liverworts, hornworts and mosses. embryophytes are multicellular eukaryotes descended from an ancestor that obtained its energy from sunlight by photosynthesis. they have life cycles with alternating haploid and diploid phases. the sexual haploid phase of embryophytes, known as the gametophyte, nurtures the developing diploid embryo sporophyte within its tissues for at least part of its life, even in the seed plants, where the gametophyte itself is nurtured by its parent sporophyte. other groups of organisms that were previously studied by botanists include bacteria ( now studied in bacteriology ), fungi ( mycology ) – including lichen - forming fungi ( lichenology ), non - chlorophyte algae ( phycology ), and viruses ( virology ). however, attention is still given to these groups by botanists, and fungi ( including lichens ) and photos by chlorophyll a is initially in the form of electrons ( and later a proton gradient ) that is used to make molecules of atp and nadph which temporarily store and transport energy. their energy is used in the light - independent reactions of the calvin cycle by the enzyme rubisco to produce molecules of the 3 - carbon sugar glyceraldehyde 3 - phosphate ( g3p ). glyceraldehyde 3 - phosphate is the first product of photosynthesis and the raw material from which glucose and almost all other organic molecules of biological origin are synthesised. some of the glucose is converted to starch which is stored in the chloroplast. starch is the characteristic energy store of most land plants and algae, while inulin, a polymer of fructose is used for the same purpose in the sunflower family asteraceae. some of the glucose is converted to sucrose ( common table sugar ) for export to the rest of the plant. unlike in animals ( which lack chloroplasts ), plants and their eukaryote relatives have delegated many biochemical roles to their chloroplasts, including synthesising all their fatty acids, and most amino acids. the fatty acids that chloroplasts make are used for many things, such as providing material to build cell membranes out of and making the polymer cutin which is found in the plant cuticle that protects land plants from drying out. plants synthesise a number of unique polymers like the polysaccharide molecules cellulose, pectin and xyloglucan from which the land plant cell wall is constructed. vascular land plants make lignin, a polymer used to strengthen the secondary cell walls of xylem tracheids and vessels to keep them from collapsing when a plant sucks water through them under water stress. lignin is also used in other cell types like sclerenchyma fibres that provide structural support for a plant and is a major constituent of wood. sporopollenin is a chemically resistant polymer found in the outer cell walls of spores and pollen of land plants responsible for the survival of early land plant spores and the pollen of seed plants in the fossil record. it is widely regarded as a marker for the start of land plant evolution during the ordovician period. the concentration of carbon dioxide in the atmosphere today is much lower than it was when plants emerged onto land during the ordovician and silurian periods. from the oil of jasminum grandiflorum which regulates wound responses in plants by unblocking the expression of genes required in the systemic acquired resistance response to pathogen attack. in addition to being the primary energy source for plants, light functions as a signalling device, providing information to the plant, such as how much sunlight the plant receives each day. this can result in adaptive changes in a process known as photomorphogenesis. phytochromes are the photoreceptors in a plant that are sensitive to light. = = plant anatomy and morphology = = plant anatomy is the study of the structure of plant cells and tissues, whereas plant morphology is the study of their external form. all plants are multicellular eukaryotes, their dna stored in nuclei. the characteristic features of plant cells that distinguish them from those of animals and fungi include a primary cell wall composed of the polysaccharides cellulose, hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and electrons to drive the synthesis of glucose by fixing atmospheric carbon dioxide into existing organic carbon compounds, such as ribulose bisphosphate ( rubp ) in a sequence of light - independent ( or dark ) reactions called the calvin cycle. = = = cell signaling = = = cell signaling ( or communication ) is the ability of cells to receive, process, and transmit signals with its environment and with itself. signals can be non - chemical such as light, electrical impulses, and heat, or chemical signals ( or ligands ) that interact with receptors, which can be found embedded in the cell membrane of another cell or located deep inside a cell. there are generally four types of chemical signals : autocrine, paracrine, juxtacrine, and hormones. in autocrine signaling, the ligand affects the same cell that releases it. tumor cells, for example, can reproduce uncontrollably because they release signals that initiate their their primary metabolism like the photosynthetic calvin cycle and crassulacean acid metabolism. others make specialised materials like the cellulose and lignin used to build their bodies, and secondary products like resins and aroma compounds. plants and various other groups of photosynthetic eukaryotes collectively known as " algae " have unique organelles known as chloroplasts. chloroplasts are thought to be descended from cyanobacteria that formed endosymbiotic relationships with ancient plant and algal ancestors. chloroplasts and cyanobacteria contain the blue - green pigment chlorophyll a. chlorophyll a ( as well as its plant and green algal - specific cousin chlorophyll b ) absorbs light in the blue - violet and orange / red parts of the spectrum while reflecting and transmitting the green light that we see as the characteristic colour of these organisms. the energy in the red and blue light that these pigments absorb is used by chloroplasts to make energy - rich carbon compounds from carbon dioxide and water by oxygenic photosynthesis, a process that generates molecular oxygen ( o2 ) as a by - product. the light energy captured by chlorophyll a is initially in the form of electrons ( and later a proton gradient ) that is used to make molecules of atp and nadph which temporarily store and transport energy. their energy is used in the light - independent reactions of the calvin cycle by the enzyme rubisco to produce molecules of the 3 - carbon sugar glyceraldehyde 3 - phosphate ( g3p ). glyceraldehyde 3 - phosphate is the first product of photosynthesis and the raw material from which glucose and almost all other organic molecules of biological origin are synthesised. some of the glucose is converted to starch which is stored in the chloroplast. starch is the characteristic energy store of most land plants and algae, while inulin, a polymer of fructose is used for the same purpose in the sunflower family asteraceae. some of the glucose is converted to sucrose ( common table sugar ) for export to the rest of the plant. unlike in animals ( which lack chloroplasts ), plants and their eukaryote relatives have delegated many biochemical roles to their chloroplasts, including synthesising all their fatty acids, and most amino acids. the fatty acids that Question: What does a solar power plant turn sunlight into? A) batteries B) electricity C) mechanical energy D) machinery	B) electricity
Context: factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic the motion and photon emission of electrons in a superlattice may be described as in an undulator. therefore, there is a close analogy between ballistic electrons in a superlattice and electrons in a free electron laser ( fel ). touching upon this analogy the intensity of photon emission in the ir region and the gain are calculated. it is shown that the amplification can be significant, reaching tens of percent. activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer. thus, because vibrational and rotational energy levels are more closely spaced than electronic energy levels, heat is more easily transferred between substances relative to light or other forms of electronic energy. for example, ultraviolet electromagnetic radiation is not transferred with as much efficacy from one substance to another as thermal or electrical energy. the existence of characteristic energy levels for different chemical substances is useful for their identification by the analysis of spectral lines. different kinds of spectra are often used in chemical spectroscopy, e. g. ir, microwave, nmr, esr, etc. spectroscopy is also used to identify the composition of remote objects – like stars and distant galaxies – by a rydberg gas of no entrained in a supersonic molecular beam releases electrons as it evolves to form an ultracold plasma. the size of this signal, compared with that extracted by the subsequent application of a pulsed electric field, determines the absolute magnitude of the plasma charge. this information, combined with the number density of ions, supports a simple thermochemical model that explains the evolution of the plasma to an ultracold electron temperature. the cross section of elastic electron - proton scattering taking place in an electron gas is calculated within the closed time path method. it is found to be the sum of two terms, one being the expression in the vacuum except that it involves dressing due to the electron gas. the other term is due to the scattering particles - electron gas entanglement. this term dominates the usual one when the exchange energy is in the vicinity of the fermi energy. furthermore it makes the trajectories of the colliding particles more consistent and the collision more irreversible, rendering the scattering more classical in this regime. analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( scale. thus, solutions that have a low ph have a high hydronium ion concentration and can be said to be more acidic. the other measurement, based on the brønsted – lowry definition, is the acid dissociation constant ( ka ), which measures the relative ability of a substance to act as an acid under the brønsted – lowry definition of an acid. that is, substances with a higher ka are more likely to donate hydrogen ions in chemical reactions than those with lower ka values. = = = redox = = = redox ( reduction - oxidation ) reactions include all chemical reactions in which atoms have their oxidation state changed by either gaining electrons ( reduction ) or losing electrons ( oxidation ). substances that have the ability to oxidize other substances are said to be oxidative and are known as oxidizing agents, oxidants or oxidizers. an oxidant removes electrons from another substance. similarly, substances that have the ability to reduce other substances are said to be reductive and are known as reducing agents, reductants, or reducers. a reductant transfers electrons to another substance and is thus oxidized itself. and because it " donates " electrons it is also called an electron donor. oxidation and reduction properly refer to a change in oxidation number — the actual transfer of electrons may never occur. thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. = = = equilibrium = = = although the concept of equilibrium is widely used across sciences, in the context of chemistry, it arises whenever a number of different states of the chemical composition are possible, as for example, in a mixture of several chemical compounds that can react with one another, or when a substance can be present in more than one kind of phase. a system of chemical substances at equilibrium, even though having an unchanging composition, is most often not static ; molecules of the substances continue to react with one another thus giving rise to a dynamic equilibrium. thus the concept describes the state in which the parameters such as chemical composition remain unchanged over time. = = = chemical laws = = = chemical reactions are governed by certain laws, which have become fundamental concepts in chemistry. some of them are : = = history = = the history of chemistry spans a period from the ancient past to the present. since several millennia bc, civilizations were using technologies that would eventually form the basis of the various branches of chemistry. examples include extracting metals from ores . a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of . oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( i. e. ' microscopic chemical events ' ). = = = ions and salts = = = an ion is a charged species, an atom or a molecule, that has lost or gained one or more electrons. when an atom loses an electron and thus has more protons than electrons, the atom is a positively charged ion or cation. when an atom gains an electron and thus has more electrons than protons, the atom is a negatively charged ion or anion. cations and anions can form a crystalline lattice of neutral salts, such as the na + and cl− ions forming sodium chloride, or nacl. examples of polyatomic ions that do not split up during acid – base reactions are hydroxide ( oh− ) and phosphate ( po43− ). plasma is composed of gaseous matter that has been completely ionized, usually through high temperature. = = = acidity and basicity = = = a substance can often be endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer Question: Moving electrons have a form of kinetic energy called what? A) electrical energy B) electromagnetism C) deformed energy D) potential energy	A) electrical energy
Context: carbon chains are sometimes considered as possible carriers of some diffuse interstellar bands. spectroscopic observations in uv band carried by spectrometer stis fed with hst, give us the possibility to detect many interstellar molecules. we focused our attention on c2 molecule and we detected it in spectra of three reddened stars ( hd27778, hd147933, hd207198 ). interstellar molecule c2 was detected as a set of absorption lines around 2313 angstroms. pigment chlorophyll a. chlorophyll a ( as well as its plant and green algal - specific cousin chlorophyll b ) absorbs light in the blue - violet and orange / red parts of the spectrum while reflecting and transmitting the green light that we see as the characteristic colour of these organisms. the energy in the red and blue light that these pigments absorb is used by chloroplasts to make energy - rich carbon compounds from carbon dioxide and water by oxygenic photosynthesis, a process that generates molecular oxygen ( o2 ) as a by - product. the light energy captured by chlorophyll a is initially in the form of electrons ( and later a proton gradient ) that is used to make molecules of atp and nadph which temporarily store and transport energy. their energy is used in the light - independent reactions of the calvin cycle by the enzyme rubisco to produce molecules of the 3 - carbon sugar glyceraldehyde 3 - phosphate ( g3p ). glyceraldehyde 3 - phosphate is the first product of photosynthesis and the raw material from which glucose and almost all other organic molecules of biological origin are synthesised. some of the glucose is converted to starch which is stored in the chloroplast. starch is the characteristic energy store of most land plants and algae, while inulin, a polymer of fructose is used for the same purpose in the sunflower family asteraceae. some of the glucose is converted to sucrose ( common table sugar ) for export to the rest of the plant. unlike in animals ( which lack chloroplasts ), plants and their eukaryote relatives have delegated many biochemical roles to their chloroplasts, including synthesising all their fatty acids, and most amino acids. the fatty acids that chloroplasts make are used for many things, such as providing material to build cell membranes out of and making the polymer cutin which is found in the plant cuticle that protects land plants from drying out. plants synthesise a number of unique polymers like the polysaccharide molecules cellulose, pectin and xyloglucan from which the land plant cell wall is constructed. vascular land plants make lignin, a polymer used to strengthen the secondary cell walls of xylem tracheids and vessels to keep them from collapsing when a plant sucks water through them under water stress. lignin much sunlight the plant receives each day. this can result in adaptive changes in a process known as photomorphogenesis. phytochromes are the photoreceptors in a plant that are sensitive to light. = = plant anatomy and morphology = = plant anatomy is the study of the structure of plant cells and tissues, whereas plant morphology is the study of their external form. all plants are multicellular eukaryotes, their dna stored in nuclei. the characteristic features of plant cells that distinguish them from those of animals and fungi include a primary cell wall composed of the polysaccharides cellulose, hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable of creating cells of the other and producing adventitious shoots or roots. stolons and tubers are examples of shoots that can grow roots. roots that spread out close to the surface, such as those of willows, can produce shoots and ultimately new plants. in the event that one of the systems is lost reflectometer ), which takes measurements in the visible region ( and a little beyond ) of a given color sample. if the custom of taking readings at 10 nanometer increments is followed, the visible light range of 400 – 700 nm will yield 31 readings. these readings are typically used to draw the sample ' s spectral reflectance curve ( how much it reflects, as a function of wavelength ) — the most accurate data that can be provided regarding its characteristics. the readings by themselves are typically not as useful as their tristimulus values, which can be converted into chromaticity co - ordinates and manipulated through color space transformations. for this purpose, a spectrocolorimeter may be used. a spectrocolorimeter is simply a spectrophotometer that can estimate tristimulus values by numerical integration ( of the color matching functions ' inner product with the illuminant ' s spectral power distribution ). one benefit of spectrocolorimeters over tristimulus colorimeters is that they do not have optical filters, which are subject to manufacturing variance, and have a fixed spectral transmittance curve — until they age. on the other hand, tristimulus colorimeters are purpose - built, cheaper, and easier to use. the cie ( international commission on illumination ) recommends using measurement intervals under 5 nm, even for smooth spectra. sparser measurements fail to accurately characterize spiky emission spectra, such as that of the red phosphor of a crt display, depicted aside. = = = color temperature meter = = = photographers and cinematographers use information provided by these meters to decide what color balancing should be done to make different light sources appear to have the same color temperature. if the user enters the reference color temperature, the meter can calculate the mired difference between the measurement and the reference, enabling the user to choose a corrective color gel or photographic filter with the closest mired factor. internally the meter is typically a silicon photodiode tristimulus colorimeter. the correlated color temperature can be calculated from the tristimulus values by first calculating the chromaticity co - ordinates in the cie 1960 color space, then finding the closest point on the planckian locus. = = see also = = color science photometry radiometry = = references = = = = further reading = = schanda, janos d. ( 1997 ). " colorimetry " ( pdf ). in casimer decusatis ( ed. ). handbook from the oil of jasminum grandiflorum which regulates wound responses in plants by unblocking the expression of genes required in the systemic acquired resistance response to pathogen attack. in addition to being the primary energy source for plants, light functions as a signalling device, providing information to the plant, such as how much sunlight the plant receives each day. this can result in adaptive changes in a process known as photomorphogenesis. phytochromes are the photoreceptors in a plant that are sensitive to light. = = plant anatomy and morphology = = plant anatomy is the study of the structure of plant cells and tissues, whereas plant morphology is the study of their external form. all plants are multicellular eukaryotes, their dna stored in nuclei. the characteristic features of plant cells that distinguish them from those of animals and fungi include a primary cell wall composed of the polysaccharides cellulose, hemicellulose and pectin, larger vacuoles than in animal cells and the presence of plastids with unique photosynthetic and biosynthetic functions as in the chloroplasts. other plastids contain storage products such as starch ( amyloplasts ) or lipids ( elaioplasts ). uniquely, streptophyte cells and those of the green algal order trentepohliales divide by construction of a phragmoplast as a template for building a cell plate late in cell division. the bodies of vascular plants including clubmosses, ferns and seed plants ( gymnosperms and angiosperms ) generally have aerial and subterranean subsystems. the shoots consist of stems bearing green photosynthesising leaves and reproductive structures. the underground vascularised roots bear root hairs at their tips and generally lack chlorophyll. non - vascular plants, the liverworts, hornworts and mosses do not produce ground - penetrating vascular roots and most of the plant participates in photosynthesis. the sporophyte generation is nonphotosynthetic in liverworts but may be able to contribute part of its energy needs by photosynthesis in mosses and hornworts. the root system and the shoot system are interdependent – the usually nonphotosynthetic root system depends on the shoot system for food, and the usually photosynthetic shoot system depends on water and minerals from the root system. cells in each system are capable excess lightweight products of slow neutron capture in the photosphere, over the mass range of 25 to 207 amu, confirm the solar mass separation recorded by excess lightweight isotopes in the solar wind, over the mass range of 3 to 136 amu [ solar abundance of the elements, meteoritics, volume 18, 1983, pages 209 to 222 ]. both measurements show that major elements inside the sun are fe, o, ni, si and s, like those in rocky planets. the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in the transpiration stream. diffusion, osmosis, and active transport and mass flow are all different ways transport can occur. examples of elements that plants need to transport are nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur. in vascular plants, these elements are extracted from the soil as soluble ions by the roots and transported throughout the plant in the xylem. most of the elements required for plant nutrition come from the chemical breakdown of soil minerals. sucrose produced by photosynthesis is transported from the leaves to other parts of the plant in the phloem and plant hormones are transported by a variety of processes. = = = plant hormones = = = plants are not passive, but respond to external signals such as light, touch, and injury by moving or growing towards or away from the stimulus, as appropriate. tangible evidence of touch sensitivity is the almost instantaneous collapse of leaflets of mimosa pudica, the insect traps of venus flytrap and bladderworts, and the pollinia of orchids. the hypothesis that plant growth and development is coordinated by plant hormones or plant growth regulators first emerged in the late 19th century. darwin experimented on the movements of plant shoots and roots towards light and gravity, and concluded " it is hardly an exaggeration to say that the tip of the radicle.. acts like the brain of one of the lower animals.. directing the several movements ". about the same time, the role of auxins ( from the greek auxein, to grow ) in control of plant growth was first outlined by the dutch scientist of a light source can be measured with a spectroradiometer, which works by optically collecting the light, then passing it through a monochromator before reading it in narrow bands of wavelength. reflected color can be measured using a spectrophotometer ( also called spectroreflectometer or reflectometer ), which takes measurements in the visible region ( and a little beyond ) of a given color sample. if the custom of taking readings at 10 nanometer increments is followed, the visible light range of 400 – 700 nm will yield 31 readings. these readings are typically used to draw the sample ' s spectral reflectance curve ( how much it reflects, as a function of wavelength ) — the most accurate data that can be provided regarding its characteristics. the readings by themselves are typically not as useful as their tristimulus values, which can be converted into chromaticity co - ordinates and manipulated through color space transformations. for this purpose, a spectrocolorimeter may be used. a spectrocolorimeter is simply a spectrophotometer that can estimate tristimulus values by numerical integration ( of the color matching functions ' inner product with the illuminant ' s spectral power distribution ). one benefit of spectrocolorimeters over tristimulus colorimeters is that they do not have optical filters, which are subject to manufacturing variance, and have a fixed spectral transmittance curve — until they age. on the other hand, tristimulus colorimeters are purpose - built, cheaper, and easier to use. the cie ( international commission on illumination ) recommends using measurement intervals under 5 nm, even for smooth spectra. sparser measurements fail to accurately characterize spiky emission spectra, such as that of the red phosphor of a crt display, depicted aside. = = = color temperature meter = = = photographers and cinematographers use information provided by these meters to decide what color balancing should be done to make different light sources appear to have the same color temperature. if the user enters the reference color temperature, the meter can calculate the mired difference between the measurement and the reference, enabling the user to choose a corrective color gel or photographic filter with the closest mired factor. internally the meter is typically a silicon photodiode tristimulus colorimeter. the correlated color temperature can be calculated from the tristimulus values by first calculating the chromaticity co - ordinates in the cie 1960 color space, then finding the closest the separation of dark and regular matter during galactic collisions. finally, the spitzer space telescope is an infrared telescope launched in 2003 from a delta ii rocket. it is in a trailing orbit around the sun, following the earth and discovered the existence of brown dwarf stars. other telescopes, such as the cosmic background explorer and the wilkinson microwave anisotropy probe, provided evidence to support the big bang. the james webb space telescope, named after the nasa administrator who lead the apollo program, is an infrared observatory launched in 2021. the james webb space telescope is a direct successor to the hubble space telescope, intended to observe the formation of the first galaxies. other space telescopes include the kepler space telescope, launched in 2009 to identify planets orbiting extrasolar stars that may be terran and possibly harbor life. the first exoplanet that the kepler space telescope confirmed was kepler - 22b, orbiting within the habitable zone of its star. nasa also launched a number of different satellites to study earth, such as television infrared observation satellite ( tiros ) in 1960, which was the first weather satellite. nasa and the united states weather bureau cooperated on future tiros and the second generation nimbus program of weather satellites. it also worked with the environmental science services administration on a series of weather satellites and the agency launched its experimental applications technology satellites into geosynchronous orbit. nasa ' s first dedicated earth observation satellite, landsat, was launched in 1972. this led to nasa and the national oceanic and atmospheric administration jointly developing the geostationary operational environmental satellite and discovering ozone depletion. = = = space shuttle = = = nasa had been pursuing spaceplane development since the 1960s, blending the administration ' s dual aeronautics and space missions. nasa viewed a spaceplane as part of a larger program, providing routine and economical logistical support to a space station in earth orbit that would be used as a hub for lunar and mars missions. a reusable launch vehicle would then have ended the need for expensive and expendable boosters like the saturn v. in 1969, nasa designated the johnson space center as the lead center for the design, development, and manufacturing of the space shuttle orbiter, while the marshall space flight center would lead the development of the launch system. nasa ' s series of lifting body aircraft, culminating in the joint nasa - us air force martin marietta x - 24, directly informed the development of the space shuttle and future hypersonic flight aircraft. official development of the space shuttle began in 1972, with rockwell international contracted to the status of the theory of color confinemnt is discussed. Question: Sunlight contains many different wavelengths, which you see when they separate into what? A) rainbow B) charges C) sounds D) shadows	A) rainbow
Context: to epidemiology and evidence - based medicine. cytology is the microscopic study of individual cells. embryology is the study of the early development of organisms. endocrinology is the study of hormones and their effect throughout the body of animals. epidemiology is the study of the demographics of disease processes, and includes, but is not limited to, the study of epidemics. genetics is the study of genes, and their role in biological inheritance. gynecology is the study of female reproductive system. histology is the study of the structures of biological tissues by light microscopy, electron microscopy and immunohistochemistry. immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. lifestyle medicine is the study of the chronic conditions, and how to prevent, treat and reverse them. medical physics is the study of the applications of physics principles in medicine. microbiology is the study of microorganisms, including protozoa, bacteria, fungi, and viruses. molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material. neuroscience includes those disciplines of science that are related to the study of the nervous system. a main focus of neuroscience is the biology and physiology of the human brain and spinal cord. some related clinical specialties include neurology, neurosurgery and psychiatry. nutrition science ( theoretical focus ) and dietetics ( practical focus ) is the study of the relationship of food and drink to health and disease, especially in determining an optimal diet. medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating disorders, allergies, malnutrition, and neoplastic diseases. pathology as a science is the study of disease – the causes, course, progression and resolution thereof. pharmacology is the study of drugs and their actions. photobiology is the study of the interactions between non - ionizing radiation and living organisms. physiology is the study of the normal functioning of the body and the underlying regulatory mechanisms. radiobiology is the study of the interactions between ionizing radiation and living organisms. toxicology is the study of hazardous effects of drugs and poisons. = = = specialties = = = in the broadest meaning of " medicine ", there are many different specialties. in the uk, most specialities have their own body or college, which has its own entrance examination. these are collectively known contrast to macroscopic or gross anatomy, cytology and histology are concerned with microscopic structures. biochemistry is the study of the chemistry taking place in living organisms, especially the structure and function of their chemical components. biomechanics is the study of the structure and function of biological systems by means of the methods of mechanics. biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems. biostatistics is the application of statistics to biological fields in the broadest sense. a knowledge of biostatistics is essential in the planning, evaluation, and interpretation of medical research. it is also fundamental to epidemiology and evidence - based medicine. cytology is the microscopic study of individual cells. embryology is the study of the early development of organisms. endocrinology is the study of hormones and their effect throughout the body of animals. epidemiology is the study of the demographics of disease processes, and includes, but is not limited to, the study of epidemics. genetics is the study of genes, and their role in biological inheritance. gynecology is the study of female reproductive system. histology is the study of the structures of biological tissues by light microscopy, electron microscopy and immunohistochemistry. immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. lifestyle medicine is the study of the chronic conditions, and how to prevent, treat and reverse them. medical physics is the study of the applications of physics principles in medicine. microbiology is the study of microorganisms, including protozoa, bacteria, fungi, and viruses. molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material. neuroscience includes those disciplines of science that are related to the study of the nervous system. a main focus of neuroscience is the biology and physiology of the human brain and spinal cord. some related clinical specialties include neurology, neurosurgery and psychiatry. nutrition science ( theoretical focus ) and dietetics ( practical focus ) is the study of the relationship of food and drink to health and disease, especially in determining an optimal diet. medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating disorders, allergies, malnutrition, and neoplastic diseases. pathology as a science is the study of disease – the causes, course, progression and resolution thereof. for natural scientists, with the creation of transgenic organisms one of the most important tools for analysis of gene function. genes and other genetic information from a wide range of organisms can be inserted into bacteria for storage and modification, creating genetically modified bacteria in the process. bacteria are cheap, easy to grow, clonal, multiply quickly, relatively easy to transform and can be stored at - 80 °c almost indefinitely. once a gene is isolated it can be stored inside the bacteria providing an unlimited supply for research. organisms are genetically engineered to discover the functions of certain genes. this could be the effect on the phenotype of the organism, where the gene is expressed or what other genes it interacts with. these experiments generally involve loss of function, gain of function, tracking and expression. loss of function experiments, such as in a gene knockout experiment, in which an organism is engineered to lack the activity of one or more genes. in a simple knockout a copy of the desired gene has been altered to make it non - functional. embryonic stem cells incorporate the altered gene, which replaces the already present functional copy. these stem cells are injected into blastocysts, which are implanted into surrogate mothers. this allows the experimenter to analyse the defects caused by this mutation and thereby determine the role of particular genes. it is used especially frequently in developmental biology. when this is done by creating a library of genes with point mutations at every position in the area of interest, or even every position in the whole gene, this is called " scanning mutagenesis ". the simplest method, and the first to be used, is " alanine scanning ", where every position in turn is mutated to the unreactive amino acid alanine. gain of function experiments, the logical counterpart of knockouts. these are sometimes performed in conjunction with knockout experiments to more finely establish the function of the desired gene. the process is much the same as that in knockout engineering, except that the construct is designed to increase the function of the gene, usually by providing extra copies of the gene or inducing synthesis of the protein more frequently. gain of function is used to tell whether or not a protein is sufficient for a function, but does not always mean it is required, especially when dealing with genetic or functional redundancy. tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. one way to do this is to replace the wild - type gene with a ' fusion ' gene, which is a juxtaposition . biophysics is an interdisciplinary science that uses the methods of physics and physical chemistry to study biological systems. biostatistics is the application of statistics to biological fields in the broadest sense. a knowledge of biostatistics is essential in the planning, evaluation, and interpretation of medical research. it is also fundamental to epidemiology and evidence - based medicine. cytology is the microscopic study of individual cells. embryology is the study of the early development of organisms. endocrinology is the study of hormones and their effect throughout the body of animals. epidemiology is the study of the demographics of disease processes, and includes, but is not limited to, the study of epidemics. genetics is the study of genes, and their role in biological inheritance. gynecology is the study of female reproductive system. histology is the study of the structures of biological tissues by light microscopy, electron microscopy and immunohistochemistry. immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. lifestyle medicine is the study of the chronic conditions, and how to prevent, treat and reverse them. medical physics is the study of the applications of physics principles in medicine. microbiology is the study of microorganisms, including protozoa, bacteria, fungi, and viruses. molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material. neuroscience includes those disciplines of science that are related to the study of the nervous system. a main focus of neuroscience is the biology and physiology of the human brain and spinal cord. some related clinical specialties include neurology, neurosurgery and psychiatry. nutrition science ( theoretical focus ) and dietetics ( practical focus ) is the study of the relationship of food and drink to health and disease, especially in determining an optimal diet. medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating disorders, allergies, malnutrition, and neoplastic diseases. pathology as a science is the study of disease – the causes, course, progression and resolution thereof. pharmacology is the study of drugs and their actions. photobiology is the study of the interactions between non - ionizing radiation and living organisms. physiology is the study of the normal functioning of the body and the underlying regulatory mechanisms. radiobiology is the study of the interactions between ionizing radiation and living organisms. , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive biology is the scientific study of life and living organisms. it is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, origin, evolution, and distribution of life. central to biology are five fundamental themes : the cell as the basic unit of life, genes and heredity as the basis of inheritance, evolution as the driver of biological diversity, energy transformation for sustaining life processes, and the maintenance of internal stability ( homeostasis ). biology examines life across multiple levels of organization, from molecules and cells to organisms, populations, and ecosystems. subdisciplines include molecular biology, physiology, ecology, evolutionary biology, developmental biology, and systematics, among others. each of these fields applies a range of methods to investigate biological phenomena, including observation, experimentation, and mathematical modeling. modern biology is grounded in the theory of evolution by natural selection, first articulated by charles darwin, and in the molecular understanding of genes encoded in dna. the discovery of the structure of dna and advances in molecular genetics have transformed many areas of biology, leading to applications in medicine, agriculture, biotechnology, and environmental science. life on earth is believed to have originated over 3. 7 billion years ago. today, it includes a vast diversity of organisms — from single - celled archaea and bacteria to complex multicellular plants, fungi, and animals. biologists classify organisms based on shared characteristics and evolutionary relationships, using taxonomic and phylogenetic frameworks. these organisms interact with each other and with their environments in ecosystems, where they play roles in energy flow and nutrient cycling. as a constantly evolving field, biology incorporates new discoveries and technologies that enhance the understanding of life and its processes, while contributing to solutions for challenges such as disease, climate change, and biodiversity loss. = = history = = the earliest of roots of science, which included medicine, can be traced to ancient egypt and mesopotamia in around 3000 to 1200 bce. their contributions shaped ancient greek natural philosophy. ancient greek philosophers such as aristotle ( 384 – 322 bce ) contributed extensively to the development of biological knowledge. he explored biological causation and the diversity of life. his successor, theophrastus, began the scientific study of plants. scholars of the medieval islamic world who wrote on biology included al - jahiz ( 781 – 869 ), al - dinawari ( 828 – 896 ), who wrote on botany, and rhazes ( 865 – 925 ) who wrote on anatomy and physiology. medicine was especially well groups of organisms. divisions related to the broader historical sense of botany include bacteriology, mycology ( or fungology ), and phycology – respectively, the study of bacteria, fungi, and algae – with lichenology as a subfield of mycology. the narrower sense of botany as the study of embryophytes ( land plants ) is called phytology. bryology is the study of mosses ( and in the broader sense also liverworts and hornworts ). pteridology ( or filicology ) is the study of ferns and allied plants. a number of other taxa of ranks varying from family to subgenus have terms for their study, including agrostology ( or graminology ) for the study of grasses, synantherology for the study of composites, and batology for the study of brambles. study can also be divided by guild rather than clade or grade. for example, dendrology is the study of woody plants. many divisions of biology have botanical subfields. these are commonly denoted by prefixing the word plant ( e. g. plant taxonomy, plant ecology, plant anatomy, plant morphology, plant systematics ), or prefixing or substituting the prefix phyto - ( e. g. phytochemistry, phytogeography ). the study of fossil plants is called palaeobotany. other fields are denoted by adding or substituting the word botany ( e. g. systematic botany ). phytosociology is a subfield of plant ecology that classifies and studies communities of plants. the intersection of fields from the above pair of categories gives rise to fields such as bryogeography, the study of the distribution of mosses. different parts of plants also give rise to their own subfields, including xylology, carpology ( or fructology ), and palynology, these being the study of wood, fruit and pollen / spores respectively. botany also overlaps on the one hand with agriculture, horticulture and silviculture, and on the other hand with medicine and pharmacology, giving rise to fields such as agronomy, horticultural botany, phytopathology, and phytopharmacology. = = scope and importance = = the study of plants is vital because they underpin almost all animal life on earth by generating a large proportion of the oxygen and food that provide humans and other organisms with aerobic respiration with the chemical , and includes, but is not limited to, the study of epidemics. genetics is the study of genes, and their role in biological inheritance. gynecology is the study of female reproductive system. histology is the study of the structures of biological tissues by light microscopy, electron microscopy and immunohistochemistry. immunology is the study of the immune system, which includes the innate and adaptive immune system in humans, for example. lifestyle medicine is the study of the chronic conditions, and how to prevent, treat and reverse them. medical physics is the study of the applications of physics principles in medicine. microbiology is the study of microorganisms, including protozoa, bacteria, fungi, and viruses. molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material. neuroscience includes those disciplines of science that are related to the study of the nervous system. a main focus of neuroscience is the biology and physiology of the human brain and spinal cord. some related clinical specialties include neurology, neurosurgery and psychiatry. nutrition science ( theoretical focus ) and dietetics ( practical focus ) is the study of the relationship of food and drink to health and disease, especially in determining an optimal diet. medical nutrition therapy is done by dietitians and is prescribed for diabetes, cardiovascular diseases, weight and eating disorders, allergies, malnutrition, and neoplastic diseases. pathology as a science is the study of disease – the causes, course, progression and resolution thereof. pharmacology is the study of drugs and their actions. photobiology is the study of the interactions between non - ionizing radiation and living organisms. physiology is the study of the normal functioning of the body and the underlying regulatory mechanisms. radiobiology is the study of the interactions between ionizing radiation and living organisms. toxicology is the study of hazardous effects of drugs and poisons. = = = specialties = = = in the broadest meaning of " medicine ", there are many different specialties. in the uk, most specialities have their own body or college, which has its own entrance examination. these are collectively known as the royal colleges, although not all currently use the term " royal ". the development of a speciality is often driven by new technology ( such as the development of effective anaesthetics ) or ways of working ( such as emergency departments ) ; the new specialty leads to the formation of a unifying body of diploid embryo sporophyte within its tissues for at least part of its life, even in the seed plants, where the gametophyte itself is nurtured by its parent sporophyte. other groups of organisms that were previously studied by botanists include bacteria ( now studied in bacteriology ), fungi ( mycology ) – including lichen - forming fungi ( lichenology ), non - chlorophyte algae ( phycology ), and viruses ( virology ). however, attention is still given to these groups by botanists, and fungi ( including lichens ) and photosynthetic protists are usually covered in introductory botany courses. palaeobotanists study ancient plants in the fossil record to provide information about the evolutionary history of plants. cyanobacteria, the first oxygen - releasing photosynthetic organisms on earth, are thought to have given rise to the ancestor of plants by entering into an endosymbiotic relationship with an early eukaryote, ultimately becoming the chloroplasts in plant cells. the new photosynthetic plants ( along with their algal relatives ) accelerated the rise in atmospheric oxygen started by the cyanobacteria, changing the ancient oxygen - free, reducing, atmosphere to one in which free oxygen has been abundant for more than 2 billion years. among the important botanical questions of the 21st century are the role of plants as primary producers in the global cycling of life ' s basic ingredients : energy, carbon, oxygen, nitrogen and water, and ways that our plant stewardship can help address the global environmental issues of resource management, conservation, human food security, biologically invasive organisms, carbon sequestration, climate change, and sustainability. = = = human nutrition = = = virtually all staple foods come either directly from primary production by plants, or indirectly from animals that eat them. plants and other photosynthetic organisms are at the base of most food chains because they use the energy from the sun and nutrients from the soil and atmosphere, converting them into a form that can be used by animals. this is what ecologists call the first trophic level. the modern forms of the major staple foods, such as hemp, teff, maize, rice, wheat and other cereal grasses, pulses, bananas and plantains, as well as hemp, flax and cotton grown for their fibres, are the outcome of prehistoric selection over thousands of years from among wild ancestral plants with the most by which botanists group organisms into categories such as genera or species. biological classification is a form of scientific taxonomy. modern taxonomy is rooted in the work of carl linnaeus, who grouped species according to shared physical characteristics. these groupings have since been revised to align better with the darwinian principle of common descent – grouping organisms by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the Question: The study of how organisms develop is known as? A) embryology B) botany C) ethology D) physics	A) embryology
Context: in a voltaic cell, positive ( negative ) ions flow from the low ( high ) potential electrode to the high ( low ) potential electrode, driven by an ` electromotive force ' which points in opposite direction and overcomes the electric force. similarly in a superconductor charge flows in direction opposite to that dictated by the faraday electric field as the magnetic field is expelled in the meissner effect. the puzzle is the same in both cases : what drives electric charges against electromagnetic forces? i propose that the answer is also the same in both cases : kinetic energy lowering, or ` quantum pressure '. = = when 0 is said to be neither positive nor negative, the following phrases may refer to the sign of a number : a number is positive if it is greater than zero. a number is negative if it is less than zero. a number is non - negative if it is greater than or equal to zero. a number is non - positive if it is less than or equal to zero. when 0 is said to be both positive and negative, modified phrases are used to refer to the sign of a number : a number is strictly positive if it is greater than zero. a number is strictly negative if it is less than zero. a number is positive if it is greater than or equal to zero. a number is negative if it is less than or equal to zero. for example, the absolute value of a real number is always " non - negative ", but is not necessarily " positive " in the first interpretation, whereas in the second interpretation, it is called " positive " — though not necessarily " strictly positive ". the same terminology is sometimes used for functions that yield real or other signed values. for example, a function would be called a positive function if its values are positive for all arguments of its domain, or a non - negative function if all of its values are non - negative. = = = complex numbers = = = complex numbers are impossible to order, so they cannot carry the structure of an ordered ring, and, accordingly, cannot be partitioned into positive and negative complex numbers. they do, however, share an attribute with the reals, which is called absolute value or magnitude. magnitudes are always non - negative real numbers, and to any non - zero number there belongs a positive real number, its absolute value. for example, the absolute value of −3 and the absolute value of 3 are both equal to 3. this is written in symbols as \| −3 \| = 3 and \| 3 \| = 3. in general, any arbitrary real value can be specified by its magnitude and its sign. using the standard encoding, any real value is given by the product of the magnitude and the sign in standard encoding. this relation can be generalized to define a sign for complex numbers. since the real and complex numbers both form a field and contain the positive reals, they also contain the reciprocals of the magnitudes of all non - zero numbers. this means that any non - zero number may be multiplied with the reciprocal of its magnitude, that is, divided by its magnitude. it is immediate that the quotient the project consists to determine, mathematically, the trajectory that will take an artificial satellite to fight against the air resistance. during our work, we had to consider that our satellite will crash to the surface of our planet. we started our study by understanding the system of forces that are acting between our satellite and the earth. in this work, we had to study the second law of newton by taking knowledge of the air friction, the speed of the satellite which helped us to find the equation that relates the trajectory of the satellite itself, its speed and the density of the air depending on the altitude. finally, we had to find a mathematic relation that links the density with the altitude and then we had to put it into our movement equation. in order to verify our model, we ' ll see what happens if we give a zero velocity to the satellite. odd numbers. the above definition of parity applies only to integer numbers, hence it cannot be applied to numbers with decimals or fractions like 1 / 2 or 4. 6978. see the section " higher mathematics " below for some extensions of the notion of parity to a larger class of " numbers " or in other more general settings. even and odd numbers have opposite parities, e. g., 22 ( even number ) and 13 ( odd number ) have opposite parities. in particular, the parity of zero is even. any two consecutive integers have opposite parity. a number ( i. e., integer ) expressed in the decimal numeral system is even or odd according to whether its last digit is even or odd. that is, if the last digit is 1, 3, 5, 7, or 9, then it is odd ; otherwise it is even — as the last digit of any even number is 0, 2, 4, 6, or 8. the same idea will work using any even base. in particular, a number expressed in the binary numeral system is odd if its last digit is 1 ; and it is even if its last digit is 0. in an odd base, the number is even according to the sum of its digits — it is even if and only if the sum of its digits is even. = = definition = = an even number is an integer of the form x = 2 k { \ displaystyle x = 2k } where k is an integer ; an odd number is an integer of the form x = 2 k + 1. { \ displaystyle x = 2k + 1. } an equivalent definition is that an even number is divisible by 2 : 2 \| x { \ displaystyle 2 \ \| \ x } and an odd number is not : 2 [UNK] \| x { \ displaystyle 2 \ not \| \ x } the sets of even and odd numbers can be defined as following : { 2 k : k ∈ z } { \ displaystyle \ { 2k : k \ in \ mathbb { z } \ } } { 2 k + 1 : k ∈ z } { \ displaystyle \ { 2k + 1 : k \ in \ mathbb { z } \ } } the set of even numbers is a prime ideal of z { \ displaystyle \ mathbb { z } } and the quotient ring z / 2 z { \ displaystyle \ mathbb { z } / 2 \ mathbb { z } in mathematics, parity is the property of an integer of whether it is even or odd. an integer is even if it is divisible by 2, and odd if it is not. for example, −4, 0, and 82 are even numbers, while −3, 5, 23, and 69 are odd numbers. the above definition of parity applies only to integer numbers, hence it cannot be applied to numbers with decimals or fractions like 1 / 2 or 4. 6978. see the section " higher mathematics " below for some extensions of the notion of parity to a larger class of " numbers " or in other more general settings. even and odd numbers have opposite parities, e. g., 22 ( even number ) and 13 ( odd number ) have opposite parities. in particular, the parity of zero is even. any two consecutive integers have opposite parity. a number ( i. e., integer ) expressed in the decimal numeral system is even or odd according to whether its last digit is even or odd. that is, if the last digit is 1, 3, 5, 7, or 9, then it is odd ; otherwise it is even — as the last digit of any even number is 0, 2, 4, 6, or 8. the same idea will work using any even base. in particular, a number expressed in the binary numeral system is odd if its last digit is 1 ; and it is even if its last digit is 0. in an odd base, the number is even according to the sum of its digits — it is even if and only if the sum of its digits is even. = = definition = = an even number is an integer of the form x = 2 k { \ displaystyle x = 2k } where k is an integer ; an odd number is an integer of the form x = 2 k + 1. { \ displaystyle x = 2k + 1. } an equivalent definition is that an even number is divisible by 2 : 2 \| x { \ displaystyle 2 \ \| \ x } and an odd number is not : 2 [UNK] \| x { \ displaystyle 2 \ not \| \ x } the sets of even and odd numbers can be defined as following : { 2 k : k ∈ z } { \ displaystyle \ { 2k : k \ in \ mathbb { z } \ } } { 2 k + 1 : k ∈ z } { \ displaystyle \ { 2k + men ' s sports include baseball, basketball, cross country, football, golf, swimming & diving, cheerleading, tennis and track & field ; while women ' s sports include basketball, cross country, softball, swimming and diving, tennis, track & field, cheerleading, and volleyball. their cheerleading squad has, in the past, only competed the national cheerleaders & dance association ( nca & nda ) college nationals along with buzz and the goldrush dance team competing here as well. however, in the 2022 season, goldrush competed at the universal cheerleaders & dance association ( uca & uda ) college nationals for the first time and in 2023 the cheer team will compete here for the first time as well. the institute mascots are buzz and the ramblin ' wreck. the institute ' s traditional football rival is the university of georgia ; the rivalry is considered one of the fiercest in college football. the rivalry is commonly referred to as clean, old - fashioned hate, which is also the title of a book about the subject. there is also a long - standing rivalry with clemson. tech has eighteen varsity sports : football, women ' s and men ' s basketball, baseball, softball, volleyball, golf, men ' s and women ' s tennis, men ' s and women ' s swimming and diving, men ' s and women ' s track and field, men ' s and women ' s cross country, and coed cheerleading. four georgia tech football teams were selected as national champions in news polls : 1917, 1928, 1952, and 1990. in may 2007, the women ' s tennis team won the ncaa national championship with a 4 – 2 victory over ucla, the first ever national title granted by the ncaa to tech. = = = fight songs = = = tech ' s fight song " i ' m a ramblin ' wreck from georgia tech " is known worldwide. first published in the 1908 blue print, it was adapted from an old drinking song ( " son of a gambolier " ) and embellished with trumpet flourishes by frank roman. then - vice president richard nixon and soviet premier nikita khrushchev sang the song together when they met in moscow in 1958 to reduce the tension between them. as the story goes, nixon did not know any russian songs, but khrushchev knew that one american song as it had been sung on the ed sullivan show. " i ' m a ramblin ' wreck " has had many other notable moments in its history the recent report on laser cooling of liquid may contradict the law of energy conservation. , only competed the national cheerleaders & dance association ( nca & nda ) college nationals along with buzz and the goldrush dance team competing here as well. however, in the 2022 season, goldrush competed at the universal cheerleaders & dance association ( uca & uda ) college nationals for the first time and in 2023 the cheer team will compete here for the first time as well. the institute mascots are buzz and the ramblin ' wreck. the institute ' s traditional football rival is the university of georgia ; the rivalry is considered one of the fiercest in college football. the rivalry is commonly referred to as clean, old - fashioned hate, which is also the title of a book about the subject. there is also a long - standing rivalry with clemson. tech has eighteen varsity sports : football, women ' s and men ' s basketball, baseball, softball, volleyball, golf, men ' s and women ' s tennis, men ' s and women ' s swimming and diving, men ' s and women ' s track and field, men ' s and women ' s cross country, and coed cheerleading. four georgia tech football teams were selected as national champions in news polls : 1917, 1928, 1952, and 1990. in may 2007, the women ' s tennis team won the ncaa national championship with a 4 – 2 victory over ucla, the first ever national title granted by the ncaa to tech. = = = fight songs = = = tech ' s fight song " i ' m a ramblin ' wreck from georgia tech " is known worldwide. first published in the 1908 blue print, it was adapted from an old drinking song ( " son of a gambolier " ) and embellished with trumpet flourishes by frank roman. then - vice president richard nixon and soviet premier nikita khrushchev sang the song together when they met in moscow in 1958 to reduce the tension between them. as the story goes, nixon did not know any russian songs, but khrushchev knew that one american song as it had been sung on the ed sullivan show. " i ' m a ramblin ' wreck " has had many other notable moments in its history. it is reportedly the first school song to have been played in space. gregory peck sang the song while strumming a ukulele in the movie the man in the gray flannel suit. john wayne whistled it in the high and the mighty. tim holt ' s character sings a few bars of it in so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : 42 – 48 confirmation bias is a form of cognitive bias. : 553 from the literature, astrology believers often tend to selectively remember those predictions that turned out to be true and do not remember those that turned out false. another, separate, form of confirmation bias also plays a role, where believers often fail to . this, he argued, would have been more persuasive and would have produced less controversy. the use of poetic imagery based on the concepts of the macrocosm and microcosm, " as above so below " to decide meaning such as edward w. james ' example of " mars above is red, so mars below means blood and war ", is a false cause fallacy. : 26 many astrologers claim that astrology is scientific. if one were to attempt to try to explain it scientifically, there are only four fundamental forces ( conventionally ), limiting the choice of possible natural mechanisms. : 65 some astrologers have proposed conventional causal agents such as electromagnetism and gravity. the strength of these forces drops off with distance. : 65 scientists reject these proposed mechanisms as implausible since, for example, the magnetic field, when measured from earth, of a large but distant planet such as jupiter is far smaller than that produced by ordinary household appliances. astronomer phil plait noted that in terms of magnitude, the sun is the only object with an electromagnetic field of note, but astrology isn ' t based just off the sun alone. : 65 while astrologers could try to suggest a fifth force, this is inconsistent with the trends in physics with the unification of electromagnetism and the weak force into the electroweak force. if the astrologer insisted on being inconsistent with the current understanding and evidential basis of physics, that would be an extraordinary claim. : 65 it would also be inconsistent with the other forces which drop off with distance. : 65 if distance is irrelevant, then, logically, all objects in space should be taken into account. : 66 carl jung sought to invoke synchronicity, the claim that two events have some sort of acausal connection, to explain the lack of statistically significant results on astrology from a single study he conducted. however, synchronicity itself is considered neither testable nor falsifiable. the study was subsequently heavily criticised for its non - random sample and its use of statistics and also its lack of consistency with astrology. = = psychology = = psychological studies have not found any robust relationship between astrological signs and life outcomes. for example, a study showed that zodiac signs are no more effective than random numbers in predicting subjective well - being and quality of life. it has also been shown that confirmation bias is a psychological factor that contributes to belief in astrology. : 344 : 180 – 181 : Question: What type of force always opposes the direction of motion? A) binary friction B) harmonic friction C) kinetic friction D) strong force	C) kinetic friction
Context: this process may release or absorb energy. when the resulting nucleus is lighter than that of iron, energy is normally released ; when the nucleus is heavier than that of iron, energy is generally absorbed. this process of fusion occurs in stars, which derive their energy from hydrogen and helium. they form, through stellar nucleosynthesis, the light elements ( lithium to calcium ) as well as some of the heavy elements ( beyond iron and nickel, via the s - process ). the remaining abundance of heavy elements, from nickel to uranium and beyond, is due to supernova nucleosynthesis, the r - process. of course, these natural processes of astrophysics are not examples of nuclear " technology ". because of the very strong repulsion of nuclei, fusion is difficult to achieve in a controlled fashion. hydrogen bombs, formally known as thermonuclear weapons, obtain their enormous destructive power from fusion, but their energy cannot be controlled. controlled fusion is achieved in particle accelerators ; this is how many synthetic elements are produced. a fusor can also produce controlled fusion and is a useful neutron source. however, both of these devices operate at a net energy loss. controlled, viable fusion power has proven elusive, despite the occasional hoax. technical and theoretical difficulties have hindered the development of working civilian fusion technology, though research continues to this day around the world. nuclear fusion was initially pursued only in theoretical stages during world war ii, when scientists on the manhattan project ( led by edward teller ) investigated it as a method to build a bomb. the project abandoned fusion after concluding that it would require a fission reaction to detonate. it took until 1952 for the first full hydrogen bomb to be detonated, so - called because it used reactions between deuterium and tritium. fusion reactions are much more energetic per unit mass of fuel than fission reactions, but starting the fusion chain reaction is much more difficult. = = nuclear weapons = = a nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission or a combination of fission and fusion. both reactions release vast quantities of energy from relatively small amounts of matter. even small nuclear devices can devastate a city by blast, fire and radiation. nuclear weapons are considered weapons of mass destruction, and their use and control has been a major aspect of international policy since their debut. the design of a nuclear weapon is more complicated than it might seem. such a weapon must hold one or more subcritical fissile masses stable for deployment, then induce criticality to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. if there are enough immediate decays to carry on the chain reaction, the mass is said to be prompt critical, and the energy release will grow rapidly and uncontrollably, usually leading to an explosion. when discovered on the eve of world war ii, this insight led multiple countries to begin programs investigating the possibility of constructing an atomic bomb — a weapon which utilized fission reactions to generate far more energy than could be created with chemical explosives. the manhattan project, run by the united states with the help of the united kingdom and canada, developed multiple fission weapons which were used against japan in 1945 at hiroshima and nagasaki. during the project, the first fission reactors were developed as well, though they were primarily for weapons manufacture and did not generate electricity. in 1951, the first nuclear fission power plant was the first to produce electricity at the experimental breeder reactor no. 1 ( ebr - 1 ), in arco, idaho, ushering in the " atomic age " of more intensive human energy use. however, if the mass is critical only when the delayed neutrons are included, then the reaction can be controlled, for example by the introduction or removal of neutron absorbers. this is what allows nuclear reactors to be built. fast neutrons are not easily captured by nuclei hazard. many of the scientists working on radioactivity died of cancer as a result of their exposure. radioactive patent medicines mostly disappeared, but other applications of radioactive materials persisted, such as the use of radium salts to produce glowing dials on meters. as the atom came to be better understood, the nature of radioactivity became clearer. some larger atomic nuclei are unstable, and so decay ( release matter or energy ) after a random interval. the three forms of radiation that becquerel and the curies discovered are also more fully understood. alpha decay is when a nucleus releases an alpha particle, which is two protons and two neutrons, equivalent to a helium nucleus. beta decay is the release of a beta particle, a high - energy electron. gamma decay releases gamma rays, which unlike alpha and beta radiation are not matter but electromagnetic radiation of very high frequency, and therefore energy. this type of radiation is the most dangerous and most difficult to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. if there are enough immediate decays to carry on the chain reaction, the mass is said to be prompt critical, and the energy release will grow rapidly and uncontrollably, usually leading to an explosion. when discovered on the eve of world war ii, this insight led multiple countries to begin programs investigating the possibility , they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. if there are enough immediate decays to carry on the chain reaction, the mass is said to be prompt critical, and the energy release will grow rapidly and uncontrollably, usually leading to an explosion. when discovered on the eve of world war ii, this insight led multiple countries to begin programs investigating the possibility of constructing an atomic bomb — a weapon which utilized fission reactions to generate far more energy than could be created with chemical explosives. the manhattan project, run by the united states with the help of the united kingdom and canada, developed multiple fission weapons which were used against japan in 1945 at hiroshima and nagasaki. during the project, the first fission reactors were developed as well, though they were primarily for weapons manufacture and did not generate electricity. in 1951, the first nuclear fission power plant was the first to produce electricity at the experimental breeder reactor no. 1 ( ebr - 1 ), in arco, idaho, ushering in the " atomic age " of more intensive human energy use. however, if the mass is critical only when the delayed neutrons are included, then the reaction can be controlled, for example by the introduction or removal of neutron absorbers. this is what allows nuclear reactors to be built. fast neutrons are not easily captured by nuclei ; they must be slowed ( slow neutrons ), generally by collision with the nuclei of a neutron moderator, before they can be easily captured. today, this type of fission is commonly used to generate electricity. = = = nuclear fusion = = = if nuclei are forced to collide, they can undergo nuclear fusion. this process may release or absorb energy. when the resulting nucleus is lighter than that of iron, energy is normally released ; when the nucleus is heavier than that of iron, energy is generally absorbed. this process of fusion occurs in stars, which derive their energy from hydrogen and helium. they form, through stellar nucleos two neutrons, equivalent to a helium nucleus. beta decay is the release of a beta particle, a high - energy electron. gamma decay releases gamma rays, which unlike alpha and beta radiation are not matter but electromagnetic radiation of very high frequency, and therefore energy. this type of radiation is the most dangerous and most difficult to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. if there are enough immediate decays to carry on the chain reaction, the mass is said to be prompt critical, and the energy release will grow rapidly and uncontrollably, usually leading to an explosion. when discovered on the eve of world war ii, this insight led multiple countries to begin programs investigating the possibility of constructing an atomic bomb — a weapon which utilized fission reactions to generate far more energy than could be created with chemical explosives. the manhattan project, run by the united states with the help of the united kingdom and canada, developed multiple fission weapons which were used against japan in 1945 at hiroshima and nagasaki. during the project, the first fission reactors were developed as well, though they were primarily for weapons manufacture and did not generate electricity. in 1951, the first nuclear fission power plant was the first to produce electricity at the experimental breeder reactor no. 1 ( ebr - 1 ), in arco, idaho, ushering in the " analyzing their radiation spectra. the term chemical energy is often used to indicate the potential of a chemical substance to undergo a transformation through a chemical reaction or to transform other chemical substances. = = = reaction = = = when a chemical substance is transformed as a result of its interaction with another substance or with energy, a chemical reaction is said to have occurred. a chemical reaction is therefore a concept related to the " reaction " of a substance when it comes in close contact with another, whether as a mixture or a solution ; exposure to some form of energy, or both. it results in some energy exchange between the constituents of the reaction as well as with the system environment, which may be designed vessels — often laboratory glassware. chemical reactions can result in the formation or dissociation of molecules, that is, molecules breaking apart to form two or more molecules or rearrangement of atoms within or across molecules. chemical reactions usually involve the making or breaking of chemical bonds. oxidation, reduction, dissociation, acid – base neutralization and molecular rearrangement are some examples of common chemical reactions. a chemical reaction can be symbolically depicted through a chemical equation. while in a non - nuclear chemical reaction the number and kind of atoms on both sides of the equation are equal, for a nuclear reaction this holds true only for the nuclear particles viz. protons and neutrons. the sequence of steps in which the reorganization of chemical bonds may be taking place in the course of a chemical reaction is called its mechanism. a chemical reaction can be envisioned to take place in a number of steps, each of which may have a different speed. many reaction intermediates with variable stability can thus be envisaged during the course of a reaction. reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. many physical chemists specialize in exploring and proposing the mechanisms of various chemical reactions. several empirical rules, like the woodward – hoffmann rules often come in handy while proposing a mechanism for a chemical reaction. according to the iupac gold book, a chemical reaction is " a process that results in the interconversion of chemical species. " accordingly, a chemical reaction may be an elementary reaction or a stepwise reaction. an additional caveat is made, in that this definition includes cases where the interconversion of conformers is experimentally observable. such detectable chemical reactions normally involve sets of molecular entities as indicated by this definition, but it is often conceptually convenient to use the term also for changes involving single molecular entities ( quack medicine ( as had the discoveries of electricity and magnetism, earlier ), and a number of patent medicines and treatments involving radioactivity were put forward. gradually it was realized that the radiation produced by radioactive decay was ionizing radiation, and that even quantities too small to burn could pose a severe long - term hazard. many of the scientists working on radioactivity died of cancer as a result of their exposure. radioactive patent medicines mostly disappeared, but other applications of radioactive materials persisted, such as the use of radium salts to produce glowing dials on meters. as the atom came to be better understood, the nature of radioactivity became clearer. some larger atomic nuclei are unstable, and so decay ( release matter or energy ) after a random interval. the three forms of radiation that becquerel and the curies discovered are also more fully understood. alpha decay is when a nucleus releases an alpha particle, which is two protons and two neutrons, equivalent to a helium nucleus. beta decay is the release of a beta particle, a high - energy electron. gamma decay releases gamma rays, which unlike alpha and beta radiation are not matter but electromagnetic radiation of very high frequency, and therefore energy. this type of radiation is the most dangerous and most difficult to block. all three types of radiation occur naturally in certain elements. it has also become clear that the ultimate source of most terrestrial energy is nuclear, either through radiation from the sun caused by stellar thermonuclear reactions or by radioactive decay of uranium within the earth, the principal source of geothermal energy. = = = nuclear fission = = = in natural nuclear radiation, the byproducts are very small compared to the nuclei from which they originate. nuclear fission is the process of splitting a nucleus into roughly equal parts, and releasing energy and neutrons in the process. if these neutrons are captured by another unstable nucleus, they can fission as well, leading to a chain reaction. the average number of neutrons released per nucleus that go on to fission another nucleus is referred to as k. values of k larger than 1 mean that the fission reaction is releasing more neutrons than it absorbs, and therefore is referred to as a self - sustaining chain reaction. a mass of fissile material large enough ( and in a suitable configuration ) to induce a self - sustaining chain reaction is called a critical mass. when a neutron is captured by a suitable nucleus, fission may occur immediately, or the nucleus may persist in an unstable state for a short time. atomic age " of more intensive human energy use. however, if the mass is critical only when the delayed neutrons are included, then the reaction can be controlled, for example by the introduction or removal of neutron absorbers. this is what allows nuclear reactors to be built. fast neutrons are not easily captured by nuclei ; they must be slowed ( slow neutrons ), generally by collision with the nuclei of a neutron moderator, before they can be easily captured. today, this type of fission is commonly used to generate electricity. = = = nuclear fusion = = = if nuclei are forced to collide, they can undergo nuclear fusion. this process may release or absorb energy. when the resulting nucleus is lighter than that of iron, energy is normally released ; when the nucleus is heavier than that of iron, energy is generally absorbed. this process of fusion occurs in stars, which derive their energy from hydrogen and helium. they form, through stellar nucleosynthesis, the light elements ( lithium to calcium ) as well as some of the heavy elements ( beyond iron and nickel, via the s - process ). the remaining abundance of heavy elements, from nickel to uranium and beyond, is due to supernova nucleosynthesis, the r - process. of course, these natural processes of astrophysics are not examples of nuclear " technology ". because of the very strong repulsion of nuclei, fusion is difficult to achieve in a controlled fashion. hydrogen bombs, formally known as thermonuclear weapons, obtain their enormous destructive power from fusion, but their energy cannot be controlled. controlled fusion is achieved in particle accelerators ; this is how many synthetic elements are produced. a fusor can also produce controlled fusion and is a useful neutron source. however, both of these devices operate at a net energy loss. controlled, viable fusion power has proven elusive, despite the occasional hoax. technical and theoretical difficulties have hindered the development of working civilian fusion technology, though research continues to this day around the world. nuclear fusion was initially pursued only in theoretical stages during world war ii, when scientists on the manhattan project ( led by edward teller ) investigated it as a method to build a bomb. the project abandoned fusion after concluding that it would require a fission reaction to detonate. it took until 1952 for the first full hydrogen bomb to be detonated, so - called because it used reactions between deuterium and tritium. fusion reactions are much more energetic per unit mass of fuel than fission reactions, but starting the fusion chain reaction is much more radiation exposure. marie curie died from aplastic anemia which resulted from her high levels of exposure. two scientists, an american and canadian respectively, harry daghlian and louis slotin, died after mishandling the same plutonium mass. unlike conventional weapons, the intense light, heat, and explosive force is not the only deadly component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. civilian nuclear and radiological accidents primarily involve nuclear power plants. most common are nuclear leaks that expose workers to hazardous material. a nuclear meltdown refers to the more serious hazard of releasing nuclear material into the surrounding environment. the most significant meltdowns occurred at three mile island in pennsylvania and chernobyl in the soviet ukraine. the earthquake and tsunami on march 11, 2011 caused serious damage to three nuclear reactors and a spent fuel storage pond at the fukushima daiichi nuclear power plant in japan. military reactors that experienced similar accidents were windscale in the united kingdom and sl - 1 in the united states. military accidents usually involve the loss or unexpected detonation of nuclear weapons. the castle bravo test in 1954 produced a larger yield than expected, which contaminated nearby islands, a japanese fishing boat ( with one fatality ), and raised concerns about contaminated fish in japan. in the 1950s through 1970s, several nuclear bombs were lost from submarines and aircraft, some of which have never been recovered. the last twenty years have seen a marked decline in such accidents. = = examples of environmental benefits = = proponents of nuclear energy note that annually, nuclear - generated electricity reduces 470 million metric tons of carbon dioxide emissions that would otherwise come from fossil fuels. additionally, the amount of comparatively low waste that nuclear energy does create is safely disposed of by the large scale nuclear energy production facilities or it is repurposed / recycled for other energy uses. proponents of nuclear energy also bring to attention the opportunity cost of utilizing other forms of electricity. for example, the environmental protection agency estimates that coal kills 30, 000 people a year, as a result of its environmental impact, while 60 people died in the chernobyl disaster. a real world example of impact provided by proponents of nuclear energy is the 650, 000 ton increase in carbon emissions in the two months following the closure of the vermont yankee nuclear plant. = = see also = = atomic age lists of nuclear disasters and radioactive incidents nuclear power debate outline of nuclear technology radiology = = references = = = = external links = = nuclear energy institute – beneficial uses liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and Question: What kind of energy is released when the nucleus of an atom is split? A) microwave B) atomic C) nuclear D) kinetic	C) nuclear
Context: enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest layer. in all, the atmosphere is made up of about 78. 0 % nitrogen, 20. 9 % oxygen, and 0. 92 % argon, and small amounts of other gases including co2 and water vapor. water vapor and co2 cause the earth ' s atmosphere to catch and hold the sun ' s energy through the greenhouse effect. this makes earth ' s surface warm enough for liquid water and life. in addition to trapping heat, the atmosphere also protects living organisms by shielding the earth ' s surface from cosmic rays. the magnetic field — created by the internal motions of the core — produces the magnetosphere which protects earth ' s atmosphere from the solar wind. as the earth is 4. 5 billion years old, it would have lost its atmosphere by now if there were no protective magnetosphere. = = earth ' s magnetic field = = = = hydrology = = hydrology is the study of the hydrosphere and the movement of water on earth. it emphasizes the study of how humans use and interact with freshwater supplies. study of water ' s movement is closely related to geomorphology and other branches of earth science. applied hydrology involves engineering to maintain aquatic environments and distribute water supplies. subdisciplines of hydrology include oceanography, hydrogeology, ecohydrology, and glaciology. oceanography is the study of oceans. hydrogeology is the study of groundwater. it includes the mapping of groundwater supplies and the analysis of groundwater contaminants. applied hydrogeology seeks to prevent contamination of groundwater and mineral springs and make it available as drinking water. the earliest exploitation of groundwater resources dates back to 3000 bc, and hydrogeology as a science was developed by hydrologists beginning in the 17th century. ecohydrology is the study of ecological systems in the hydrosphere. it can be divided into the physical study of aquatic ecosystems and the the paper erroneously assumed that the normal carriers giving rise to the backflow could be either electrons or holes. ambient air ( see lockheed f - 117 nighthawk, rectangular nozzles on the lockheed martin f - 22 raptor, and serrated nozzle flaps on the lockheed martin f - 35 lightning ). often, cool air is deliberately injected into the exhaust flow to boost this process ( see ryan aqm - 91 firefly and northrop b - 2 spirit ). the stefan – boltzmann law shows how this results in less energy ( thermal radiation in infrared spectrum ) being released and thus reduces the heat signature. in some aircraft, the jet exhaust is vented above the wing surface to shield it from observers below, as in the lockheed f - 117 nighthawk, and the unstealthy fairchild republic a - 10 thunderbolt ii. to achieve infrared stealth, the exhaust gas is cooled to the temperatures where the brightest wavelengths it radiates are absorbed by atmospheric carbon dioxide and water vapor, greatly reducing the infrared visibility of the exhaust plume. another way to reduce the exhaust temperature is to circulate coolant fluids such as fuel inside the exhaust pipe, where the fuel tanks serve as heat sinks cooled by the flow of air along the wings. ground combat includes the use of both active and passive infrared sensors. thus, the united states marine corps ( usmc ) ground combat uniform requirements document specifies infrared reflective quality standards. = = reducing radio frequency ( rf ) emissions = = in addition to reducing infrared and acoustic emissions, a stealth vehicle must avoid radiating any other detectable energy, such as from onboard radars, communications systems, or rf leakage from electronics enclosures. the f - 117 uses passive infrared and low light level television sensor systems to aim its weapons and the f - 22 raptor has an advanced lpi radar which can illuminate enemy aircraft without triggering a radar warning receiver response. = = measuring = = the size of a target ' s image on radar is measured by the rcs, often represented by the symbol σ and expressed in square meters. this does not equal geometric area. a perfectly conducting sphere of projected cross sectional area 1 m2 ( i. e. a diameter of 1. 13 m ) will have an rcs of 1 m2. note that for radar wavelengths much less than the diameter of the sphere, rcs is independent of frequency. conversely, a square flat plate of area 1 m2 will have an rcs of σ = 4π a2 / λ2 ( where a = area, λ = wavelength ), or 13, 982 m2 at 10 ghz if the radar is perpendicular to the flat cools and solidifies. through subduction, oceanic crust and lithosphere vehemently returns to the convecting mantle. volcanoes result primarily from the melting of subducted crust material. crust material that is forced into the asthenosphere melts, and some portion of the melted material becomes light enough to rise to the surface — giving birth to volcanoes. = = atmospheric science = = atmospheric science initially developed in the late - 19th century as a means to forecast the weather through meteorology, the study of weather. atmospheric chemistry was developed in the 20th century to measure air pollution and expanded in the 1970s in response to acid rain. climatology studies the climate and climate change. the troposphere, stratosphere, mesosphere, thermosphere, and exosphere are the five layers which make up earth ' s atmosphere. 75 % of the mass in the atmosphere is located within the troposphere, the lowest layer. in all, the atmosphere is made up of about 78. 0 % nitrogen, 20. 9 % oxygen, and 0. 92 % argon, and small amounts of other gases including co2 and water vapor. water vapor and co2 cause the earth ' s atmosphere to catch and hold the sun ' s energy through the greenhouse effect. this makes earth ' s surface warm enough for liquid water and life. in addition to trapping heat, the atmosphere also protects living organisms by shielding the earth ' s surface from cosmic rays. the magnetic field — created by the internal motions of the core — produces the magnetosphere which protects earth ' s atmosphere from the solar wind. as the earth is 4. 5 billion years old, it would have lost its atmosphere by now if there were no protective magnetosphere. = = earth ' s magnetic field = = = = hydrology = = hydrology is the study of the hydrosphere and the movement of water on earth. it emphasizes the study of how humans use and interact with freshwater supplies. study of water ' s movement is closely related to geomorphology and other branches of earth science. applied hydrology involves engineering to maintain aquatic environments and distribute water supplies. subdisciplines of hydrology include oceanography, hydrogeology, ecohydrology, and glaciology. oceanography is the study of oceans. hydrogeology is the study of groundwater. it includes the mapping of groundwater supplies and the analysis of groundwater contaminants. applied hydrogeology seeks to prevent contamination of groundwater and mineral springs and make team of physicists who were concerned that nazi germany might also be seeking to build a bomb based on nuclear fission. ( the earliest known nuclear reaction on earth occurred naturally, 1. 7 billion years ago, in oklo, gabon, africa. ) the second artificial nuclear reactor, the x - 10 graphite reactor, was also a part of the manhattan project, as were the plutonium - producing reactors of the hanford engineer works. the first nuclear reactor to generate electricity was experimental breeder reactor i ( ebr - i ), which did so near arco, idaho, in 1951. ebr - i was a standalone facility, not connected to a grid, but a later idaho research reactor in the borax series did briefly supply power to the town of arco in 1955. the first commercial nuclear power plant, built to be connected to an electrical grid, is the obninsk nuclear power plant, which began operation in 1954. the second is the shippingport atomic power station, which produced electricity in 1957. for a chronology, from the discovery of uranium to the current era, see outline history of nuclear energy or history of nuclear power. also see history of nuclear engineering part 1 : radioactivity, part 2 : building the bomb, and part 3 : atoms for peace. see list of commercial nuclear reactors for a comprehensive listing of nuclear power reactors and iaea power reactor information system ( pris ) for worldwide and country - level statistics on nuclear power generation. = = sub - disciplines = = nuclear engineers work in such areas as the following : nuclear reactor design, which has evolved from the generation i, proof - of concept, reactors of the 1950s and 1960s, to generation ii, generation iii, and generation iv concepts thermal hydraulics and heat transfer. in a typical nuclear power plant, heat generates steam that drives a steam turbine and a generator that produces electricity materials science as it relates to nuclear power applications managing the nuclear fuel cycle, in which fissile material is obtained, formed into fuel, removed when depleted, and safely stored or reprocessed nuclear propulsion, mainly for military naval vessels, but there have been concepts for aircraft and missiles. nuclear power has been used in space since the 1960s plasma physics, which is integral to the development of fusion power weapons development and management generation of radionuclides, which have applications in industry, medicine, and many other areas nuclear waste management health physics nuclear medicine and medical physics health and safety instrumentation and control engineering process engineering project management quality engineering reactor operations nuclear security ( detection of the infrared excess around the white dwarf g29 - 38 can be explained by emission from an opaque flat ring of dust with an inner radius 0. 14 of the radius of the sun and an outer radius approximately equal to the sun ' s. this ring lies within the roche region of the white dwarf where an asteroid could have been tidally destroyed, producing a system reminiscent of saturn ' s rings. accretion onto the white dwarf from this circumstellar dust can explain the observed calcium abundance in the atmosphere of g29 - 38. either as a bombardment by a series of asteroids or because of one large disruption, the total amount of matter accreted onto the white dwarf may have been comparable to the total mass of asteroids in the solar system, or, equivalently, about 1 % of the mass in the asteroid belt around the main sequence star zeta lep. ( potassium hydroxide ), where si < 111 > planes etch approximately 100 times slower than other planes ( crystallographic orientations ). therefore, etching a rectangular hole in a ( 100 ) - si wafer results in a pyramid shaped etch pit with 54. 7° walls, instead of a hole with curved sidewalls as with isotropic etching. hydrofluoric acid is commonly used as an aqueous etchant for silicon dioxide ( sio2, also known as box for soi ), usually in 49 % concentrated form, 5 : 1, 10 : 1 or 20 : 1 boe ( buffered oxide etchant ) or bhf ( buffered hf ). they were first used in medieval times for glass etching. it was used in ic fabrication for patterning the gate oxide until the process step was replaced by rie. hydrofluoric acid is considered one of the more dangerous acids in the cleanroom. electrochemical etching ( ece ) for dopant - selective removal of silicon is a common method to automate and to selectively control etching. an active p – n diode junction is required, and either type of dopant can be the etch - resistant ( " etch - stop " ) material. boron is the most common etch - stop dopant. in combination with wet anisotropic etching as described above, ece has been used successfully for controlling silicon diaphragm thickness in commercial piezoresistive silicon pressure sensors. selectively doped regions can be created either by implantation, diffusion, or epitaxial deposition of silicon. = = = = dry etching = = = = xenon difluoride ( xef2 ) is a dry vapor phase isotropic etch for silicon originally applied for mems in 1995 at university of california, los angeles. primarily used for releasing metal and dielectric structures by undercutting silicon, xef2 has the advantage of a stiction - free release unlike wet etchants. its etch selectivity to silicon is very high, allowing it to work with photoresist, sio2, silicon nitride, and various metals for masking. its reaction to silicon is " plasmaless ", is purely chemical and spontaneous and is often operated in pulsed mode. models of the etching action are available, and university laboratories and various commercial tools offer solutions using this approach. modern in this article i explain in detail a method for making small amounts of liquid oxygen in the classroom if there is no access to a cylinder of compressed oxygen gas. i also discuss two methods for identifying the fact that it is liquid oxygen as opposed to liquid nitrogen. ##s ( sometimes called pressurized caissons ), which penetrate soft mud, are bottomless boxes sealed at the top and filled with compressed air to keep water and mud out at depth. an airlock allows access to the chamber. workers, called sandhogs in american english, move mud and rock debris ( called muck ) from the edge of the workspace to a water - filled pit, connected by a tube ( called the muck tube ) to the surface. a crane at the surface removes the soil with a clamshell bucket. the water pressure in the tube balances the air pressure, with excess air escaping up the muck tube. the pressurized air flow must be constant to ensure regular air changes for the workers and prevent excessive inflow of mud or water at the base of the caisson. when the caisson hits bedrock, the sandhogs exit through the airlock and fill the box with concrete, forming a solid foundation pier. a pneumatic ( compressed - air ) caisson has the advantage of providing dry working conditions, which is better for placing concrete. it is also well suited for foundations for which other methods might cause settlement of adjacent structures. construction workers who leave the pressurized environment of the caisson must decompress at a rate that allows symptom - free release of inert gases dissolved in the body tissues if they are to avoid decompression sickness, a condition first identified in caisson workers, and originally named " caisson disease " in recognition of the occupational hazard. construction of the brooklyn bridge, which was built with the help of pressurised caissons, resulted in numerous workers being either killed or permanently injured by caisson disease during its construction. barotrauma of the ears, sinus cavities and lungs and dysbaric osteonecrosis are other risks. = = other uses = = caissons have also been used in the installation of hydraulic elevators where a single - stage ram is installed below the ground level. caissons, codenamed phoenix, were an integral part of the mulberry harbours used during the world war ii allied invasion of normandy. = = other meanings = = boat lift caissons : the word caisson is also used as a synonym for the moving trough part of caisson locks, canal lifts and inclines in which boats and ships rest while being lifted from one canal elevation to another ; the water is retained on the inside of the caisson, or excluded from the caisson given invariant percolation on a regular tree, where the probability of an edge to be open equals $ p $, is it always possible to find an infinite self - avoiding path along which the density of open edges is bigger then $ p $? Question: When did we learn there was a hole in the ozone layer? A) 1990's B) 1970s C) 1980s D) 1950s	C) 1980s
Context: young plant cells, and electroporation, which involves using an electric shock to make the cell membrane permeable to plasmid dna. as only a single cell is transformed with genetic material, the organism must be regenerated from that single cell. in plants this is accomplished through the use of tissue culture. in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes of homologous recombination and nonhomologous end - joining. there are four families of engineered nucleases : meganucleases, zinc finger nucleases, transcription activator - like effector nucleases ( talens ), and the cas9 - guiderna system ( adapted from crispr ). talen and crispr are the two most commonly used and each has its own advantages. talens have greater target specificity, while crispr is easier to design and more efficient. in addition to enhancing gene targeting, engineered nucleases can be used to introduce mutations in a voltaic cell, positive ( negative ) ions flow from the low ( high ) potential electrode to the high ( low ) potential electrode, driven by an ` electromotive force ' which points in opposite direction and overcomes the electric force. similarly in a superconductor charge flows in direction opposite to that dictated by the faraday electric field as the magnetic field is expelled in the meissner effect. the puzzle is the same in both cases : what drives electric charges against electromagnetic forces? i propose that the answer is also the same in both cases : kinetic energy lowering, or ` quantum pressure '. induced stem cells ( isc ) as related to the donor. = = = stem cells = = = stem cells are undifferentiated cells with the ability to divide in culture and give rise to different forms of specialized cells. stem cells are divided into " adult " and " embryonic " stem cells according to their source. while there is still a large ethical debate related to the use of embryonic stem cells, it is thought that another alternative source – induced pluripotent stem cells – may be useful for the repair of diseased or damaged tissues, or may be used to grow new organs. totipotent cells are stem cells which can divide into further stem cells or differentiate into any cell type in the body, including extra - embryonic tissue. pluripotent cells are stem cells which can differentiate into any cell type in the body except extra - embryonic tissue. induced pluripotent stem cells ( ipscs ) are subclass of pluripotent stem cells resembling embryonic stem cells ( escs ) that have been derived from adult differentiated cells. ipscs are created by altering the expression of transcriptional factors in adult cells until they become like embryonic stem cells. multipotent stem cells can be differentiated into any cell within the same class, such as blood or bone. a common example of multipotent cells is mesenchymal stem cells ( mscs ). = = scaffolds = = scaffolds are materials that have been engineered to cause desirable cellular interactions to contribute to the formation of new functional tissues for medical purposes. cells are often ' seeded ' into these structures capable of supporting three - dimensional tissue formation. scaffolds mimic the extracellular matrix of the native tissue, recapitulating the in vivo milieu and allowing cells to influence their own microenvironments. they usually serve at least one of the following purposes : allowing cell attachment and migration, delivering and retaining cells and biochemical factors, enabling diffusion of vital cell nutrients and expressed products, and exerting certain mechanical and biological influences to modify the behaviour of the cell phase. in 2009, an interdisciplinary team led by the thoracic surgeon thorsten walles implanted the first bioartificial transplant that provides an innate vascular network for post - transplant graft supply successfully into a patient awaiting tracheal reconstruction. to achieve the goal of tissue reconstruction, scaffolds must meet some specific requirements. high porosity and adequate pore size are necessary to facilitate cell seed industrial applications. this branch of biotechnology is the most used for the industries of refining and combustion principally on the production of bio - oils with photosynthetic micro - algae. green biotechnology is biotechnology applied to agricultural processes. an example would be the selection and domestication of plants via micropropagation. another example is the designing of transgenic plants to grow under specific environments in the presence ( or absence ) of chemicals. one hope is that green biotechnology might produce more environmentally friendly solutions than traditional industrial agriculture. an example of this is the engineering of a plant to express a pesticide, thereby ending the need of external application of pesticides. an example of this would be bt corn. whether or not green biotechnology products such as this are ultimately more environmentally friendly is a topic of considerable debate. it is commonly considered as the next phase of green revolution, which can be seen as a platform to eradicate world hunger by using technologies which enable the production of more fertile and resistant, towards biotic and abiotic stress, plants and ensures application of environmentally friendly fertilizers and the use of biopesticides, it is mainly focused on the development of agriculture. on the other hand, some of the uses of green biotechnology involve microorganisms to clean and reduce waste. red biotechnology is the use of biotechnology in the medical and pharmaceutical industries, and health preservation. this branch involves the production of vaccines and antibiotics, regenerative therapies, creation of artificial organs and new diagnostics of diseases. as well as the development of hormones, stem cells, antibodies, sirna and diagnostic tests. white biotechnology, also known as industrial biotechnology, is biotechnology applied to industrial processes. an example is the designing of an organism to produce a useful chemical. another example is the using of enzymes as industrial catalysts to either produce valuable chemicals or destroy hazardous / polluting chemicals. white biotechnology tends to consume less in resources than traditional processes used to produce industrial goods. yellow biotechnology refers to the use of biotechnology in food production ( food industry ), for example in making wine ( winemaking ), cheese ( cheesemaking ), and beer ( brewing ) by fermentation. it has also been used to refer to biotechnology applied to insects. this includes biotechnology - based approaches for the control of harmful insects, the characterisation and utilisation of active ingredients or genes of insects for research, or application in agriculture and medicine and various other approaches. gray biotechnology is dedicated to environmental applications, and focused on the maintenance of biodiversity and the remotion of poll animal cells using microinjection, where it can be injected through the cell ' s nuclear envelope directly into the nucleus, or through the use of viral vectors. plant genomes can be engineered by physical methods or by use of agrobacterium for the delivery of sequences hosted in t - dna binary vectors. in plants the dna is often inserted using agrobacterium - mediated transformation, taking advantage of the agrobacteriums t - dna sequence that allows natural insertion of genetic material into plant cells. other methods include biolistics, where particles of gold or tungsten are coated with dna and then shot into young plant cells, and electroporation, which involves using an electric shock to make the cell membrane permeable to plasmid dna. as only a single cell is transformed with genetic material, the organism must be regenerated from that single cell. in plants this is accomplished through the use of tissue culture. in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes in plants the dna is often inserted using agrobacterium - mediated transformation, taking advantage of the agrobacteriums t - dna sequence that allows natural insertion of genetic material into plant cells. other methods include biolistics, where particles of gold or tungsten are coated with dna and then shot into young plant cells, and electroporation, which involves using an electric shock to make the cell membrane permeable to plasmid dna. as only a single cell is transformed with genetic material, the organism must be regenerated from that single cell. in plants this is accomplished through the use of tissue culture. in animals it is necessary to ensure that the inserted dna is present in the embryonic stem cells. bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. selectable markers are used to easily differentiate transformed from untransformed cells. these markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant. further testing using pcr, southern hybridization, and dna sequencing is conducted to confirm that an organism contains the new gene. these tests can also confirm the chromosomal location and copy number of the inserted gene. the presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products ( rna and protein ) are also used. these include northern hybridisation, quantitative rt - pcr, western blot, immunofluorescence, elisa and phenotypic analysis. the new genetic material can be inserted randomly within the host genome or targeted to a specific location. the technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene. this tends to occur at a relatively low frequency in plants and animals and generally requires the use of selectable markers. the frequency of gene targeting can be greatly enhanced through genome editing. genome editing uses artificially engineered nucleases that create specific double - stranded breaks at desired locations in the genome, and use the cell ' s endogenous mechanisms to repair the induced break by the natural processes of homologous recombination and nonhomologous end - joining. there are four families of engineered nucleases : meganucleases, zinc finger nucleases, transcription activator - like effector nucleases ( talens ), and the cas9 - guide best - known and controversial applications of genetic engineering is the creation and use of genetically modified crops or genetically modified livestock to produce genetically modified food. crops have been developed to increase production, increase tolerance to abiotic stresses, alter the composition of the food, or to produce novel products. the first crops to be released commercially on a large scale provided protection from insect pests or tolerance to herbicides. fungal and virus resistant crops have also been developed or are in development. this makes the insect and weed management of crops easier and can indirectly increase crop yield. gm crops that directly improve yield by accelerating growth or making the plant more hardy ( by improving salt, cold or drought tolerance ) are also under development. in 2016 salmon have been genetically modified with growth hormones to reach normal adult size much faster. gmos have been developed that modify the quality of produce by increasing the nutritional value or providing more industrially useful qualities or quantities. the amflora potato produces a more industrially useful blend of starches. soybeans and canola have been genetically modified to produce more healthy oils. the first commercialised gm food was a tomato that had delayed ripening, increasing its shelf life. plants and animals have been engineered to produce materials they do not normally make. pharming uses crops and animals as bioreactors to produce vaccines, drug intermediates, or the drugs themselves ; the useful product is purified from the harvest and then used in the standard pharmaceutical production process. cows and goats have been engineered to express drugs and other proteins in their milk, and in 2009 the fda approved a drug produced in goat milk. = = = other applications = = = genetic engineering has potential applications in conservation and natural area management. gene transfer through viral vectors has been proposed as a means of controlling invasive species as well as vaccinating threatened fauna from disease. transgenic trees have been suggested as a way to confer resistance to pathogens in wild populations. with the increasing risks of maladaptation in organisms as a result of climate change and other perturbations, facilitated adaptation through gene tweaking could be one solution to reducing extinction risks. applications of genetic engineering in conservation are thus far mostly theoretical and have yet to be put into practice. genetic engineering is also being used to create microbial art. some bacteria have been genetically engineered to create black and white photographs. novelty items such as lavender - colored carnations, blue roses, and glowing fish, have also been produced through genetic engineering. = = regulation = = the regulation of genetic engineering any two generating systems of the fundamental group of a closed surface are nielsen equivalent. ##s can be tested against these mouse models. gene therapy is the genetic engineering of humans, generally by replacing defective genes with effective ones. clinical research using somatic gene therapy has been conducted with several diseases, including x - linked scid, chronic lymphocytic leukemia ( cll ), and parkinson ' s disease. in 2012, alipogene tiparvovec became the first gene therapy treatment to be approved for clinical use. in 2015 a virus was used to insert a healthy gene into the skin cells of a boy suffering from a rare skin disease, epidermolysis bullosa, in order to grow, and then graft healthy skin onto 80 percent of the boy ' s body which was affected by the illness. germline gene therapy would result in any change being inheritable, which has raised concerns within the scientific community. in 2015, crispr was used to edit the dna of non - viable human embryos, leading scientists of major world academies to call for a moratorium on inheritable human genome edits. there are also concerns that the technology could be used not just for treatment, but for enhancement, modification or alteration of a human beings ' appearance, adaptability, intelligence, character or behavior. the distinction between cure and enhancement can also be difficult to establish. in november 2018, he jiankui announced that he had edited the genomes of two human embryos, to attempt to disable the ccr5 gene, which codes for a receptor that hiv uses to enter cells. the work was widely condemned as unethical, dangerous, and premature. currently, germline modification is banned in 40 countries. scientists that do this type of research will often let embryos grow for a few days without allowing it to develop into a baby. researchers are altering the genome of pigs to induce the growth of human organs, with the aim of increasing the success of pig to human organ transplantation. scientists are creating " gene drives ", changing the genomes of mosquitoes to make them immune to malaria, and then looking to spread the genetically altered mosquitoes throughout the mosquito population in the hopes of eliminating the disease. = = = research = = = genetic engineering is an important tool for natural scientists, with the creation of transgenic organisms one of the most important tools for analysis of gene function. genes and other genetic information from a wide range of organisms can be inserted into bacteria for storage and modification, creating genetically modified bacteria in the process. bacteria are cheap, easy to grow, clonal, multi defective gene with a functioning one. it is an important tool in research that allows the function of specific genes to be studied. drugs, vaccines and other products have been harvested from organisms engineered to produce them. crops have been developed that aid food security by increasing yield, nutritional value and tolerance to environmental stresses. the dna can be introduced directly into the host organism or into a cell that is then fused or hybridised with the host. this relies on recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro - injection, macro - injection or micro - encapsulation. genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. however, some broad definitions of genetic engineering include selective breeding. cloning and stem cell research, although not considered genetic engineering, are closely related and genetic engineering can be used within them. synthetic biology is an emerging discipline that takes genetic engineering a step further by introducing artificially synthesised material into an organism. plants, animals or microorganisms that have been changed through genetic engineering are termed genetically modified organisms or gmos. if genetic material from another species is added to the host, the resulting organism is called transgenic. if genetic material from the same species or a species that can naturally breed with the host is used the resulting organism is called cisgenic. if genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a knockout organism. in europe genetic modification is synonymous with genetic engineering while within the united states of america and canada genetic modification can also be used to refer to more conventional breeding methods. = = history = = humans have altered the genomes of species for thousands of years through selective breeding, or artificial selection : 1 : 1 as contrasted with natural selection. more recently, mutation breeding has used exposure to chemicals or radiation to produce a high frequency of random mutations, for selective breeding purposes. genetic engineering as the direct manipulation of dna by humans outside breeding and mutations has only existed since the 1970s. the term " genetic engineering " was coined by the russian - born geneticist nikolay timofeev - ressovsky in his 1934 paper " the experimental production of mutations ", published in the british journal biological reviews. jack williamson used the term in his science fiction novel dragon ' Question: What type of generators use electromagnetic induction to change kinetic energy to electrical energy? A) radiators B) conductors C) thermal generators D) electric generators	D) electric generators
Context: has rest mass and volume ( it takes up space ) and is made up of particles. the particles that make up matter have rest mass as well – not all particles have rest mass, such as the photon. matter can be a pure chemical substance or a mixture of substances. = = = = atom = = = = the atom is the basic unit of chemistry. it consists of a dense core called the atomic nucleus surrounded by a space occupied by an electron cloud. the nucleus is made up of positively charged protons and uncharged neutrons ( together called nucleons ), while the electron cloud consists of negatively charged electrons which orbit the nucleus. in a neutral atom, the negatively charged electrons balance out the positive charge of the protons. the nucleus is dense ; the mass of a nucleon is approximately 1, 836 times that of an electron, yet the radius of an atom is about 10, 000 times that of its nucleus. the atom is also the smallest entity that can be envisaged to retain the chemical properties of the element, such as electronegativity, ionization potential, preferred oxidation state ( s ), coordination number, and preferred types of bonds to form ( e. g., metallic, ionic, covalent ). = = = = element = = = = a chemical element is a pure substance which is composed of a single type of atom, characterized by its particular number of protons in the nuclei of its atoms, known as the atomic number and represented by the symbol z. the mass number is the sum of the number of protons and neutrons in a nucleus. although all the nuclei of all atoms belonging to one element will have the same atomic number, they may not necessarily have the same mass number ; atoms of an element which have different mass numbers are known as isotopes. for example, all atoms with 6 protons in their nuclei are atoms of the chemical element carbon, but atoms of carbon may have mass numbers of 12 or 13. the standard presentation of the chemical elements is in the periodic table, which orders elements by atomic number. the periodic table is arranged in groups, or columns, and periods, or rows. the periodic table is useful in identifying periodic trends. = = = = compound = = = = a compound is a pure chemical substance composed of more than one element. the properties of a compound bear little similarity to those of its elements. the standard nomenclature of compounds is set by the international union of pure and applied chemistry ( iupac ). organic compounds are named or homogeneous distribution of the dispersed particle or fiber phase. consider first the processing of particulate composites. the particulate phase of greatest interest is tetragonal zirconia because of the toughening that can be achieved from the phase transformation from the metastable tetragonal to the monoclinic crystalline phase, aka transformation toughening. there is also substantial interest in dispersion of hard, non - oxide phases such as sic, tib, tic, boron, carbon and especially oxide matrices like alumina and mullite. there is also interest too incorporating other ceramic particulates, especially those of highly anisotropic thermal expansion. examples include al2o3, tio2, graphite, and boron nitride. in processing particulate composites, the issue is not only homogeneity of the size and spatial distribution of the dispersed and matrix phases, but also control of the matrix grain size. however, there is some built - in self - control due to inhibition of matrix grain growth by the dispersed phase. particulate composites, though generally offer increased resistance to damage, failure, or both, are still quite sensitive to inhomogeneities of composition as well as other processing defects such as pores. thus they need good processing to be effective. particulate composites have been made on a commercial basis by simply mixing powders of the two constituents. although this approach is inherently limited in the homogeneity that can be achieved, it is the most readily adaptable for existing ceramic production technology. however, other approaches are of interest. from the technological standpoint, a particularly desirable approach to fabricating particulate composites is to coat the matrix or its precursor onto fine particles of the dispersed phase with good control of the starting dispersed particle size and the resultant matrix coating thickness. one should in principle be able to achieve the ultimate in homogeneity of distribution and thereby optimize composite performance. this can also have other ramifications, such as allowing more useful composite performance to be achieved in a body having porosity, which might be desired for other factors, such as limiting thermal conductivity. there are also some opportunities to utilize melt processing for fabrication of ceramic, particulate, whisker and short - fiber, and continuous - fiber composites. both particulate and whisker composites are conceivable by solid - state precipitation after solidification of the melt. this can also be obtained in some cases by sintering, the crystals of potassium hydrogen carbonate ( khco3 ) and the kdco3 analogue are isomorphous. they are composed of hydrogen or deuterium bonded centrosymmetric dimers ( hco3 - ) ( 2 ) or ( dco3 - ) ( 2 ). the space group symmetry of khpd1 - pco3 ( p approximate to 0. 75 ) determined with neutron diffraction is identical to those of khco3 and kdco3. this is at variance with a random distribution of h and d nuclei. these crystals are macroscopic quantum systems in which protons or / and deuterons merge into macroscopic states. ( create a critical mass ) for detonation. it also is quite difficult to ensure that such a chain reaction consumes a significant fraction of the fuel before the device flies apart. the procurement of a nuclear fuel is also more difficult than it might seem, since sufficiently unstable substances for this process do not currently occur naturally on earth in suitable amounts. one isotope of uranium, namely uranium - 235, is naturally occurring and sufficiently unstable, but it is always found mixed with the more stable isotope uranium - 238. the latter accounts for more than 99 % of the weight of natural uranium. therefore, some method of isotope separation based on the weight of three neutrons must be performed to enrich ( isolate ) uranium - 235. alternatively, the element plutonium possesses an isotope that is sufficiently unstable for this process to be usable. terrestrial plutonium does not currently occur naturally in sufficient quantities for such use, so it must be manufactured in a nuclear reactor. ultimately, the manhattan project manufactured nuclear weapons based on each of these elements. they detonated the first nuclear weapon in a test code - named " trinity ", near alamogordo, new mexico, on july 16, 1945. the test was conducted to ensure that the implosion method of detonation would work, which it did. a uranium bomb, little boy, was dropped on the japanese city hiroshima on august 6, 1945, followed three days later by the plutonium - based fat man on nagasaki. in the wake of unprecedented devastation and casualties from a single weapon, the japanese government soon surrendered, ending world war ii. since these bombings, no nuclear weapons have been deployed offensively. nevertheless, they prompted an arms race to develop increasingly destructive bombs to provide a nuclear deterrent. just over four years later, on august 29, 1949, the soviet union detonated its first fission weapon. the united kingdom followed on october 2, 1952 ; france, on february 13, 1960 ; and china component to a nuclear weapon. approximately half of the deaths from hiroshima and nagasaki died two to five years afterward from radiation exposure. a radiological weapon is a type of nuclear weapon designed to distribute hazardous nuclear material in enemy areas. such a weapon would not have the explosive capability of a fission or fusion bomb, but would kill many people and contaminate a large area. a radiological weapon has never been deployed. while considered useless by a conventional military, such a weapon raises concerns over nuclear terrorism. there have been over 2, 000 nuclear tests conducted since 1945. in 1963, all nuclear and many non - that shows the object as it looks from the front, right, left, top, bottom, or back ( e. g. the primary views ), and is typically positioned relative to each other according to the rules of either first - angle or third - angle projection. the origin and vector direction of the projectors ( also called projection lines ) differs, as explained below. in first - angle projection, the parallel projectors originate as if radiated from behind the viewer and pass through the 3d object to project a 2d image onto the orthogonal plane behind it. the 3d object is projected into 2d " paper " space as if you were looking at a radiograph of the object : the top view is under the front view, the right view is at the left of the front view. first - angle projection is the iso standard and is primarily used in europe. in third - angle projection, the parallel projectors originate as if radiated from the far side of the object and pass through the 3d object to project a 2d image onto the orthogonal plane in front of it. the views of the 3d object are like the panels of a box that envelopes the object, and the panels pivot as they open up flat into the plane of the drawing. thus the left view is placed on the left and the top view on the top ; and the features closest to the front of the 3d object will appear closest to the front view in the drawing. third - angle projection is primarily used in the united states and canada, where it is the default projection system according to asme standard asme y14. 3m. until the late 19th century, first - angle projection was the norm in north america as well as europe ; but circa the 1890s, third - angle projection spread throughout the north american engineering and manufacturing communities to the point of becoming a widely followed convention, and it was an asa standard by the 1950s. circa world war i, british practice was frequently mixing the use of both projection methods. as shown above, the determination of what surface constitutes the front, back, top, and bottom varies depending on the projection method used. not all views are necessarily used. generally only as many views are used as are necessary to convey all needed information clearly and economically. the front, top, and right - side views are commonly considered the core group of views included by default, but any combination of views may be used depending on the needs of the particular design. in addition to the six principal views ( front, back, top, bottom, right side, left side ), the greek letter π ( pi ) ). some more complicated examples : the real part and the absolute value of a complex number are invariant under complex conjugation. the tricolorability of knots. the degree of a polynomial is invariant under a linear change of variables. the dimension and homology groups of a topological object are invariant under homeomorphism. the number of fixed points of a dynamical system is invariant under many mathematical operations. euclidean distance is invariant under orthogonal transformations. area is invariant under linear maps which have determinant ±1 ( see equiareal map § linear transformations ). some invariants of projective transformations include collinearity of three or more points, concurrency of three or more lines, conic sections, and the cross - ratio. the determinant, trace, eigenvectors, and eigenvalues of a linear endomorphism are invariant under a change of basis. in other words, the spectrum of a matrix is invariant under a change of basis. the principal invariants of tensors do not change with rotation of the coordinate system ( see invariants of tensors ). the singular values of a matrix are invariant under orthogonal transformations. lebesgue measure is invariant under translations. the variance of a probability distribution is invariant under translations of the real line. hence the variance of a random variable is unchanged after the addition of a constant. the fixed points of a transformation are the elements in the domain that are invariant under the transformation. they may, depending on the application, be called symmetric with respect to that transformation. for example, objects with translational symmetry are invariant under certain translations. the integral [UNK] m k d μ { \ textstyle \ int _ { m } k \, d \ mu } of the gaussian curvature k { \ displaystyle k } of a two - dimensional riemannian manifold ( m, g ) { \ displaystyle ( m, g ) } is invariant under changes of the riemannian metric g { \ displaystyle g }. this is the gauss – bonnet theorem. = = = mu puzzle = = = the mu puzzle is a good example of a logical problem where determining an invariant is of use for an impossibility proof. the puzzle asks one to start with the word mi and transform it into the word mu, using in each step one of the following transformation rules : if a string ends with an i, a u may be appended ( xi → xiu ) the string after the m may be completely duplicated ( . most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes shaping the cell. cell membranes are involved in various cellular processes such as cell adhesion, storing electrical energy, and cell signalling and serve as the attachment surface for several extracellular structures such as a cell wall, glycocalyx, and cytoskeleton. within the cytoplasm of a cell, there are many biomolecules such as proteins and nucleic acids. in addition to biomolecules, eukaryotic cells have specialized structures called organelles that have their own lipid bilayers or are spatially units. these organelles include the cell nucleus, which contains most of the cell ' s dna, or mitochondria, which generate adenosine triphosphate ( atp ) to power cellular processes. other organelles such as endoplasmic reticulum and golgi apparatus play a role in the synthesis and packaging of proteins, respectively. biomolecules such as proteins can be engulfed by lysosomes, another specialized organelle. plant cells have additional organelles that distinguish them from animal cells such as a cell wall that provides support for the plant cell, chloroplasts that harvest sunlight energy to produce sugar, and vacuoles that provide storage and structural support phase, aka transformation toughening. there is also substantial interest in dispersion of hard, non - oxide phases such as sic, tib, tic, boron, carbon and especially oxide matrices like alumina and mullite. there is also interest too incorporating other ceramic particulates, especially those of highly anisotropic thermal expansion. examples include al2o3, tio2, graphite, and boron nitride. in processing particulate composites, the issue is not only homogeneity of the size and spatial distribution of the dispersed and matrix phases, but also control of the matrix grain size. however, there is some built - in self - control due to inhibition of matrix grain growth by the dispersed phase. particulate composites, though generally offer increased resistance to damage, failure, or both, are still quite sensitive to inhomogeneities of composition as well as other processing defects such as pores. thus they need good processing to be effective. particulate composites have been made on a commercial basis by simply mixing powders of the two constituents. although this approach is inherently limited in the homogeneity that can be achieved, it is the most readily adaptable for existing ceramic production technology. however, other approaches are of interest. from the technological standpoint, a particularly desirable approach to fabricating particulate composites is to coat the matrix or its precursor onto fine particles of the dispersed phase with good control of the starting dispersed particle size and the resultant matrix coating thickness. one should in principle be able to achieve the ultimate in homogeneity of distribution and thereby optimize composite performance. this can also have other ramifications, such as allowing more useful composite performance to be achieved in a body having porosity, which might be desired for other factors, such as limiting thermal conductivity. there are also some opportunities to utilize melt processing for fabrication of ceramic, particulate, whisker and short - fiber, and continuous - fiber composites. both particulate and whisker composites are conceivable by solid - state precipitation after solidification of the melt. this can also be obtained in some cases by sintering, as for precipitation - toughened, partially stabilized zirconia. similarly, it is known that one can directionally solidify ceramic eutectic mixtures and hence obtain uniaxially aligned fiber composites. such composite processing has typically been limited to very simple shapes and thus suffers from serious economic problems due to index chemical substances. in this scheme each chemical substance is identifiable by a number known as its cas registry number. = = = = molecule = = = = a molecule is the smallest indivisible portion of a pure chemical substance that has its unique set of chemical properties, that is, its potential to undergo a certain set of chemical reactions with other substances. however, this definition only works well for substances that are composed of molecules, which is not true of many substances ( see below ). molecules are typically a set of atoms bound together by covalent bonds, such that the structure is electrically neutral and all valence electrons are paired with other electrons either in bonds or in lone pairs. thus, molecules exist as electrically neutral units, unlike ions. when this rule is broken, giving the " molecule " a charge, the result is sometimes named a molecular ion or a polyatomic ion. however, the discrete and separate nature of the molecular concept usually requires that molecular ions be present only in well - separated form, such as a directed beam in a vacuum in a mass spectrometer. charged polyatomic collections residing in solids ( for example, common sulfate or nitrate ions ) are generally not considered " molecules " in chemistry. some molecules contain one or more unpaired electrons, creating radicals. most radicals are comparatively reactive, but some, such as nitric oxide ( no ) can be stable. the " inert " or noble gas elements ( helium, neon, argon, krypton, xenon and radon ) are composed of lone atoms as their smallest discrete unit, but the other isolated chemical elements consist of either molecules or networks of atoms bonded to each other in some way. identifiable molecules compose familiar substances such as water, air, and many organic compounds like alcohol, sugar, gasoline, and the various pharmaceuticals. however, not all substances or chemical compounds consist of discrete molecules, and indeed most of the solid substances that make up the solid crust, mantle, and core of the earth are chemical compounds without molecules. these other types of substances, such as ionic compounds and network solids, are organized in such a way as to lack the existence of identifiable molecules per se. instead, these substances are discussed in terms of formula units or unit cells as the smallest repeating structure within the substance. examples of such substances are mineral salts ( such as table salt ), solids like carbon and diamond, metals, and familiar silica and silicate minerals such as quartz and granite. one of the main characteristics of a molecule is its geometry lengthened unnecessarily if the pattern is not being changed the second time. it is known that focused - ion beam lithography has the capability of writing extremely fine lines ( less than 50 nm line and space has been achieved ) without proximity effect. however, because the writing field in ion - beam lithography is quite small, large area patterns must be created by stitching together the small fields. ion track technology is a deep cutting tool with a resolution limit around 8 nm applicable to radiation resistant minerals, glasses and polymers. it is capable of generating holes in thin films without any development process. structural depth can be defined either by ion range or by material thickness. aspect ratios up to several 104 can be reached. the technique can shape and texture materials at a defined inclination angle. random pattern, single - ion track structures and an aimed pattern consisting of individual single tracks can be generated. x - ray lithography is a process used in the electronic industry to selectively remove parts of a thin film. it uses x - rays to transfer a geometric pattern from a mask to a light - sensitive chemical photoresist, or simply " resist ", on the substrate. a series of chemical treatments then engraves the produced pattern into the material underneath the photoresist. diamond patterning is a method of forming diamond mems. it is achieved by the lithographic application of diamond films to a substrate such as silicon. the patterns can be formed by selective deposition through a silicon dioxide mask, or by deposition followed by micromachining or focused ion beam milling. = = = etching processes = = = there are two basic categories of etching processes : wet etching and dry etching. in the former, the material is dissolved when immersed in a chemical solution. in the latter, the material is sputtered or dissolved using reactive ions or a vapor phase etchant. = = = = wet etching = = = = wet chemical etching consists of the selective removal of material by dipping a substrate into a solution that dissolves it. the chemical nature of this etching process provides good selectivity, which means the etching rate of the target material is considerably higher than the mask material if selected carefully. wet etching can be performed using either isotropic wet etchants or anisotropic wet etchants. isotropic wet etchant etch in all directions of the crystalline silicon at approximately equal rates. anisotropic wet etchants preferably etch along certain crystal Question: In the simple cubic system, the atoms or ions are located in which part of the cell? A) mitochondria B) walls C) plasma D) corners	D) corners
Context: they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea ##ning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures left no written records, the shift from nomadic life to settlement and agriculture can be inferred from a range of archaeological evidence. such evidence includes ancient tools, cave paintings, and other prehistoric art, such as the venus of willendorf. human remains also provide direct evidence, both through the examination of bones, and have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became which could be used as tools, primarily in the form of choppers or scrapers. these tools greatly aided the early humans in their hunter - gatherer lifestyle to perform a variety of tasks including butchering carcasses ( and breaking bones to get at the marrow ) ; chopping wood ; cracking open nuts ; skinning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures developed music and engaged in organized warfare. stone age humans developed ocean - worthy outrigger canoe technology, leading to migration across the malay archipelago, across the indian ocean to madagascar and also across the pacific ocean, which required knowledge of the ocean currents, weather patterns, sailing, and celestial navigation. although paleolithic cultures left no written records, the shift from nomadic life to settlement and agriculture can be inferred from a range of archaeological evidence. such evidence includes ancient tools, cave paintings, and other prehistoric art, such as the venus of willendorf. human remains also provide direct evidence, both through the examination of bones, and the study of mummies. scientists and historians have been able to form significant inferences about the lifestyle and culture of various prehistoric peoples, and especially their technology. = = = ancient = = = = = = = copper and bronze ages = = = = metallic copper occurs on the surface of weathered copper ore deposits and copper . microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of ##rozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokar unitary recordings in freely - moving pulse weakly electric fish suggest spike timing encoding of electrosensory signals into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off ##thic, or " old stone age ", and spans all of human history up to the development of agriculture approximately 12, 000 years ago. to make a stone tool, a " core " of hard stone with specific flaking properties ( such as flint ) was struck with a hammerstone. this flaking produced sharp edges which could be used as tools, primarily in the form of choppers or scrapers. these tools greatly aided the early humans in their hunter - gatherer lifestyle to perform a variety of tasks including butchering carcasses ( and breaking bones to get at the marrow ) ; chopping wood ; cracking open nuts ; skinning an animal for its hide, and even forming other tools out of softer materials such as bone and wood. the earliest stone tools were irrelevant, being little more than a fractured rock. in the acheulian era, beginning approximately 1. 65 million years ago, methods of working these stones into specific shapes, such as hand axes emerged. this early stone age is described as the lower paleolithic. the middle paleolithic, approximately 300, 000 years ago, saw the introduction of the prepared - core technique, where multiple blades could be rapidly formed from a single core stone. the upper paleolithic, beginning approximately 40, 000 years ago, saw the introduction of pressure flaking, where a wood, bone, or antler punch could be used to shape a stone very finely. the end of the last ice age about 10, 000 years ago is taken as the end point of the upper paleolithic and the beginning of the epipaleolithic / mesolithic. the mesolithic technology included the use of microliths as composite stone tools, along with wood, bone, and antler tools. the later stone age, during which the rudiments of agricultural technology were developed, is called the neolithic period. during this period, polished stone tools were made from a variety of hard rocks such as flint, jade, jadeite, and greenstone, largely by working exposures as quarries, but later the valuable rocks were pursued by tunneling underground, the first steps in mining technology. the polished axes were used for forest clearance and the establishment of crop farming and were so effective as to remain in use when bronze and iron appeared. these stone axes were used alongside a continued use of stone tools such as a range of projectiles, knives, and scrapers, as well as tools, made from organic materials such as wood, bone, and antler. stone age cultures Question: What are the earliest and simplest vertebrates? A) fish B) whales C) bears D) birds	A) fish
Context: behavioral responses to different stimuli, one can understand something about how those stimuli are processed. lewandowski & strohmetz ( 2009 ) reviewed a collection of innovative uses of behavioral measurement in psychology including behavioral traces, behavioral observations, and behavioral choice. behavioral traces are pieces of evidence that indicate behavior occurred, but the actor is not present ( e. g., litter in a parking lot or readings on an electric meter ). behavioral observations involve the direct witnessing of the actor engaging in the behavior ( e. g., watching how close a person sits next to another person ). behavioral choices are when a person selects between two or more options ( e. g., voting behavior, choice of a punishment for another participant ). reaction time. the time between the presentation of a stimulus and an appropriate response can indicate differences between two cognitive processes, and can indicate some things about their nature. for example, if in a search task the reaction times vary proportionally with the number of elements, then it is evident that this cognitive process of searching involves serial instead of parallel processing. psychophysical responses. psychophysical experiments are an old psychological technique, which has been adopted by cognitive psychology. they typically involve making judgments of some physical property, e. g. the loudness of a sound. correlation of subjective scales between individuals can show cognitive or sensory biases as compared to actual physical measurements. some examples include : sameness judgments for colors, tones, textures, etc. threshold differences for colors, tones, textures, etc. eye tracking. this methodology is used to study a variety of cognitive processes, most notably visual perception and language processing. the fixation point of the eyes is linked to an individual ' s focus of attention. thus, by monitoring eye movements, we can study what information is being processed at a given time. eye tracking allows us to study cognitive processes on extremely short time scales. eye movements reflect online decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream is not present ( e. g., litter in a parking lot or readings on an electric meter ). behavioral observations involve the direct witnessing of the actor engaging in the behavior ( e. g., watching how close a person sits next to another person ). behavioral choices are when a person selects between two or more options ( e. g., voting behavior, choice of a punishment for another participant ). reaction time. the time between the presentation of a stimulus and an appropriate response can indicate differences between two cognitive processes, and can indicate some things about their nature. for example, if in a search task the reaction times vary proportionally with the number of elements, then it is evident that this cognitive process of searching involves serial instead of parallel processing. psychophysical responses. psychophysical experiments are an old psychological technique, which has been adopted by cognitive psychology. they typically involve making judgments of some physical property, e. g. the loudness of a sound. correlation of subjective scales between individuals can show cognitive or sensory biases as compared to actual physical measurements. some examples include : sameness judgments for colors, tones, textures, etc. threshold differences for colors, tones, textures, etc. eye tracking. this methodology is used to study a variety of cognitive processes, most notably visual perception and language processing. the fixation point of the eyes is linked to an individual ' s focus of attention. thus, by monitoring eye movements, we can study what information is being processed at a given time. eye tracking allows us to study cognitive processes on extremely short time scales. eye movements reflect online decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream and taken up by the brain. by observing which areas of the brain take up the radioactive isotope, we can see which areas of the brain are more active than other areas. pet has similar spatial resolution to fmri, but it has extremely poor temporal resolution. electroencephalography. eeg measures the electrical fields cell. in juxtacrine signaling, there is direct contact between the signaling and responding cells. finally, hormones are ligands that travel through the circulatory systems of animals or vascular systems of plants to reach their target cells. once a ligand binds with a receptor, it can influence the behavior of another cell, depending on the type of receptor. for instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. other types of receptors include protein kinase receptors ( e. g., receptor for the hormone insulin ) and g protein - coupled receptors. activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions options ( e. g., voting behavior, choice of a punishment for another participant ). reaction time. the time between the presentation of a stimulus and an appropriate response can indicate differences between two cognitive processes, and can indicate some things about their nature. for example, if in a search task the reaction times vary proportionally with the number of elements, then it is evident that this cognitive process of searching involves serial instead of parallel processing. psychophysical responses. psychophysical experiments are an old psychological technique, which has been adopted by cognitive psychology. they typically involve making judgments of some physical property, e. g. the loudness of a sound. correlation of subjective scales between individuals can show cognitive or sensory biases as compared to actual physical measurements. some examples include : sameness judgments for colors, tones, textures, etc. threshold differences for colors, tones, textures, etc. eye tracking. this methodology is used to study a variety of cognitive processes, most notably visual perception and language processing. the fixation point of the eyes is linked to an individual ' s focus of attention. thus, by monitoring eye movements, we can study what information is being processed at a given time. eye tracking allows us to study cognitive processes on extremely short time scales. eye movements reflect online decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream and taken up by the brain. by observing which areas of the brain take up the radioactive isotope, we can see which areas of the brain are more active than other areas. pet has similar spatial resolution to fmri, but it has extremely poor temporal resolution. electroencephalography. eeg measures the electrical fields generated by large populations of neurons in the cortex by placing a series of electrodes on the scalp of the subject. this technique has an extremely high temporal resolution, but a relatively poor spatial resolution. functional magnetic resonance imaging. fmri measures the relative amount of oxygenated blood flowing to different parts of the brain. more oxygen can be activated by inducers are called inducible genes, in contrast to constitutive genes that are almost constantly active. in contrast to both, structural genes encode proteins that are not involved in gene regulation. in addition to regulatory events involving the promoter, gene expression can also be regulated by epigenetic changes to chromatin, which is a complex of dna and protein found in eukaryotic cells. = = = genes, development, and evolution = = = development is the process by which a multicellular organism ( plant or animal ) goes through a series of changes, starting from a single cell, and taking on various forms that are characteristic of its life cycle. there are four key processes that underlie development : determination, differentiation, morphogenesis, and growth. determination sets the developmental fate of a cell, which becomes more restrictive during development. differentiation is the process by which specialized cells arise from less specialized cells such as stem cells. stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. cellular differentiation dramatically changes a cell ' s size, shape, membrane potential, metabolic activity, and responsiveness to signals, which are largely due to highly controlled modifications in gene expression and epigenetics. with a few exceptions, cellular differentiation almost never involves a change in the dna sequence itself. thus, different cells can have very different physical characteristics despite having the same genome. morphogenesis, or the development of body form, is the result of spatial differences in gene expression. a small fraction of the genes in an organism ' s genome called the developmental - genetic toolkit control the development of that organism. these toolkit genes are highly conserved among phyla, meaning that they are ancient and very similar in widely separated groups of animals. differences in deployment of toolkit genes affect the body plan and the number, identity, and pattern of body parts. among the most important toolkit genes are the hox genes. hox genes determine where repeating parts, such as the many vertebrae of snakes, will grow in a developing embryo or larva. = = evolution = = = = = evolutionary processes = = = evolution is a central organizing concept in biology. it is the change in heritable characteristics of populations over successive generations. in artificial selection, animals were selectively bred for specific traits. given that traits are inherited, populations contain a varied mix of traits, and reproduction is able to increase any population, in one or more of these kinds of structures, it is invariably accompanied by an increase or decrease of energy of the substances involved. some energy is transferred between the surroundings and the reactants of the reaction in the form of heat or light ; thus the products of a reaction may have more or less energy than the reactants. a reaction is said to be exergonic if the final state is lower on the energy scale than the initial state ; in the case of endergonic reactions the situation is the reverse. a reaction is said to be exothermic if the reaction releases heat to the surroundings ; in the case of endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid own self - division. in paracrine signaling, the ligand diffuses to nearby cells and affects them. for example, brain cells called neurons release ligands called neurotransmitters that diffuse across a synaptic cleft to bind with a receptor on an adjacent cell such as another neuron or muscle cell. in juxtacrine signaling, there is direct contact between the signaling and responding cells. finally, hormones are ligands that travel through the circulatory systems of animals or vascular systems of plants to reach their target cells. once a ligand binds with a receptor, it can influence the behavior of another cell, depending on the type of receptor. for instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. other types of receptors include protein kinase receptors ( e. g., receptor for the hormone insulin ) and g protein - coupled receptors. activation of g protein - coupled receptors can initiate second messenger cascades. the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events is called signal transduction. = = = cell cycle = = = the cell cycle is a series of events that take place in a cell that cause it to divide into two daughter cells. these events include the duplication of its dna and some of its organelles, and the subsequent partitioning of its cytoplasm into two daughter cells in a process called cell division. in eukaryotes ( i. e., animal, plant, fungal, and protist cells ), there are two distinct types of cell division : mitosis and meiosis. mitosis is part of the cell cycle, in which replicated chromosomes are separated into two new nuclei. cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. in general, mitosis ( division of the nucleus ) is preceded by the s stage of interphase ( during which the dna is replicated ) and is often followed by telophase and cytokinesis ; which divides the cytoplasm, organelles and cell membrane of one cell into two new cells containing roughly equal shares of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as variation in total solar irradiance is thought to have little effect on the earth ' s surface temperature because of the thermal time constant - - the characteristic response time of the earth ' s global surface temperature to changes in forcing. this time constant is large enough to smooth annual variations but not necessarily variations having a longer period such as those due to solar inertial motion ; the magnitude of these surface temperature variations is estimated. superdielectric behavior was observed in pastes made of high surface area alumina filled to the level of incipient wetness with water containing dissolved sodium chloride ( table salt ). in some cases the dielectric constants were greater than 10 ^ 10. endothermic reactions, the reaction absorbs heat from the surroundings. chemical reactions are invariably not possible unless the reactants surmount an energy barrier known as the activation energy. the speed of a chemical reaction ( at given temperature t ) is related to the activation energy e, by the boltzmann ' s population factor e − e / k t { \ displaystyle e ^ { - e / kt } } – that is the probability of a molecule to have energy greater than or equal to e at the given temperature t. this exponential dependence of a reaction rate on temperature is known as the arrhenius equation. the activation energy necessary for a chemical reaction to occur can be in the form of heat, light, electricity or mechanical force in the form of ultrasound. a related concept free energy, which also incorporates entropy considerations, is a very useful means for predicting the feasibility of a reaction and determining the state of equilibrium of a chemical reaction, in chemical thermodynamics. a reaction is feasible only if the total change in the gibbs free energy is negative, δ g ≤ 0 { \ displaystyle \ delta g \ leq 0 \, } ; if it is equal to zero the chemical reaction is said to be at equilibrium. there exist only limited possible states of energy for electrons, atoms and molecules. these are determined by the rules of quantum mechanics, which require quantization of energy of a bound system. the atoms / molecules in a higher energy state are said to be excited. the molecules / atoms of substance in an excited energy state are often much more reactive ; that is, more amenable to chemical reactions. the phase of a substance is invariably determined by its energy and the energy of its surroundings. when the intermolecular forces of a substance are such that the energy of the surroundings is not sufficient to overcome them, it occurs in a more ordered phase like liquid or solid as is the case with water ( h2o ) ; a liquid at room temperature because its molecules are bound by hydrogen bonds. whereas hydrogen sulfide ( h2s ) is a gas at room temperature and standard pressure, as its molecules are bound by weaker dipole – dipole interactions. the transfer of energy from one chemical substance to another depends on the size of energy quanta emitted from one substance. however, heat energy is often transferred more easily from almost any substance to another because the phonons responsible for vibrational and rotational energy levels in a substance have much less energy than photons invoked for the electronic energy transfer Question: Behaviors are responses to stimuli. they can either be instinctual/innate behaviors, which are not influenced by the environment, or learned behaviors, which are influenced by this? A) spontaneous mutation B) environmental changes C) inheritance D) osmosis	B) environmental changes
Context: ##yotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mit the manufacturer. one common distinction is by nominal pore size. it describes the maximum pore size distribution and gives only vague information about the retention capacity of a membrane. the exclusion limit or " cut - off " of the membrane is usually specified in the form of nmwc ( nominal molecular weight cut - off, or mwco, molecular weight cut off, with units in dalton ). it is defined as the minimum molecular weight of a globular molecule that is retained to 90 % by the membrane. the cut - off, depending on the method, can by converted to so - called d90, which is then expressed in a metric unit. in practice the mwco of the membrane should be at least 20 % lower than the molecular weight of the molecule that is to be separated. using track etched mica membranes beck and schultz demonstrated that hindered diffusion of molecules in pores can be described by the rankin equation. filter membranes are divided into four classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filt mwco, molecular weight cut off, with units in dalton ). it is defined as the minimum molecular weight of a globular molecule that is retained to 90 % by the membrane. the cut - off, depending on the method, can by converted to so - called d90, which is then expressed in a metric unit. in practice the mwco of the membrane should be at least 20 % lower than the molecular weight of the molecule that is to be separated. using track etched mica membranes beck and schultz demonstrated that hindered diffusion of molecules in pores can be described by the rankin equation. filter membranes are divided into four classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filtration behavior and selectivity. the selectivity is highly dependent on the separation process, the composition of the membrane and its electrochemical properties in addition to the pore size. with high selectivity, isotopes can be enriched ( uranium enrichment ) in nuclear engineering or industrial gases like nitrogen can be recovered ( gas separation ) urinary tract infection ( utis ) is referred as one of the most common infection in medical sectors worldwide and antimicrobial resistance ( amr ) is also a global threat to human that is related with many diseases. as antibiotics used for the treatment of infectious diseases, the rate of resistance is increasing day by day. gram positive pathogens are commonly found in urine sample collected from different age groups of people, associated with uti. the study was conducted in a diagnostic center in dhaka, bangladesh with total 1308 urine samples from november 2021 to april 2022. gram positive pathogens were isolated and antimicrobial susceptibility tests were done. from total 121 samples of gram positive bacteria the highest prevalence rate of utis was found in age group of 21 - 30 year. mostly enterococcus spp. ( 33. 05 % ) staphylococcus aureus ( 27. 27 % ), streptococcus spp. ( 20. 66 % ), beta - hemolytic streptococci ( 19. 00 % ) were found as causative agents of uti compared to others. the majority of isolates have been detected as multi - drug resistant ( mdr ). the higher percentage of antibiotic resistance were found against azithromycin ( 75 % ), and cefixime ( 64. 46 % ). this research focused on the regular basis of surveillance for the gram - positive bacteria antibiotic susceptibility to increase awareness about the use of proper antibiotic thus minimize the drug resistance. the thickness of freshly made soap films is usually in the micron range, and interference colors make thickness fluctuations easily visible. circular patterns of constant thickness are commonly observed, either a thin film disc in a thicker film or the reverse. in this letter, we evidence the line tension at the origin of these circular patterns. using a well controlled soap film preparation, we produce a piece of thin film surrounded by a thicker film. the thickness profile, measured with a spectral camera, leads to a line tension of the order of 0. 1 nn which drives the relaxation of the thin film shape, initially very elongated, toward a circular shape. a balance between line tension and air friction leads to a quantitative prediction of the relaxation process. such a line tension is expected to play a role in the production of marginal regeneration patches, involved in soap film drainage and stability. the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive classes according to pore size : the form and shape of the membrane pores are highly dependent on the manufacturing process and are often difficult to specify. therefore, for characterization, test filtrations are carried out and the pore diameter refers to the diameter of the smallest particles which could not pass through the membrane. the rejection can be determined in various ways and provides an indirect measurement of the pore size. one possibility is the filtration of macromolecules ( often dextran, polyethylene glycol or albumin ), another is measurement of the cut - off by gel permeation chromatography. these methods are used mainly to measure membranes for ultrafiltration applications. another testing method is the filtration of particles with defined size and their measurement with a particle sizer or by laser induced breakdown spectroscopy ( libs ). a vivid characterization is to measure the rejection of dextran blue or other colored molecules. the retention of bacteriophage and bacteria, the so - called " bacteria challenge test ", can also provide information about the pore size. to determine the pore diameter, physical methods such as porosimeter ( mercury, liquid - liquid porosimeter and bubble point test ) are also used, but a certain form of the pores ( such as cylindrical or concatenated spherical holes ) is assumed. such methods are used for membranes whose pore geometry does not match the ideal, and we get " nominal " pore diameter, which characterizes the membrane, but does not necessarily reflect its actual filtration behavior and selectivity. the selectivity is highly dependent on the separation process, the composition of the membrane and its electrochemical properties in addition to the pore size. with high selectivity, isotopes can be enriched ( uranium enrichment ) in nuclear engineering or industrial gases like nitrogen can be recovered ( gas separation ). ideally, even racemics can be enriched with a suitable membrane. when choosing membranes selectivity has priority over a high permeability, as low flows can easily be offset by increasing the filter surface with a modular structure. in gas phase filtration different deposition mechanisms are operative, so that particles having sizes below the pore size of the membrane can be retained as well. = = membrane classification = = bio - membrane is classified in two categories, synthetic membrane and natural membrane. synthetic membranes further classified in organic and inorganic membranes. organic membrane sub classified polymeric membranes and inorganic membrane sub classified ceramic polymers. = = synthesis of biomass membrane Question: Gram-positive and gram-negative bacteria are distinguished by thickness of what? A) cell wall B) cell membrane C) cell length D) cell weight	A) cell wall
Context: ##ysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to ##simal cube of material relative to a reference configuration. mechanical strains are caused by mechanical stress, see stress - strain curve. the relationship between stress and strain is generally linear and reversible up until the yield point and the deformation is elastic. elasticity in materials occurs when applied stress does not surpass the energy required to break molecular bonds, allowing the material to deform reversibly and return to its original shape once the stress is removed. the linear relationship for a material is known as young ' s modulus. above the yield point, some degree of permanent distortion remains after unloading and is termed plastic deformation. the determination of the stress and strain throughout a solid object is given by the field of strength of materials and for a structure by structural analysis. in the above figure, it can be seen that the compressive loading ( indicated by the arrow ) has caused deformation in the cylinder so that the original shape ( dashed lines ) has changed ( deformed ) into one with bulging sides. the sides bulge because the material, although strong enough to not crack or otherwise fail, is not strong enough to support the load without change. as a result, the material is forced out laterally. internal forces ( in this case at right angles to the deformation ) resist the applied load. = = types of deformation = = depending on the type of material, size and geometry of the object, and the forces applied, various types of deformation may result. the image to the right shows the engineering stress vs. strain diagram for a typical ductile material such as steel. different deformation modes may occur under different conditions, as can be depicted using a deformation mechanism map. permanent deformation is irreversible ; the deformation stays even after removal of the applied forces, while the temporary deformation is recoverable as it disappears after the removal of applied forces. temporary deformation is also called elastic deformation, while the permanent deformation is called plastic deformation. = = = elastic deformation = = = the study of temporary or elastic deformation in the case of engineering strain is applied to materials used in mechanical and structural engineering, such as concrete and steel, which are subjected to very small deformations. engineering strain is modeled by infinitesimal strain theory, also called small strain theory, small deformation theory, small displacement theory, or small displacement - gradient theory where strains and rotations are both small. for some materials, e. g. elastomers and polymers, subjected to large deformations, the engineering definition of strain is not applicable, e. g. typical engineering strains liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of the earth ' s atmosphere, and supplies most of the energy necessary for life on earth. photosynthesis has four stages : light absorption, electron transport, atp synthesis, and carbon fixation. light absorption is the initial step of photosynthesis whereby light energy is absorbed by chlorophyll pigments attached to proteins in the thylakoid membranes. the absorbed light energy is used to remove electrons from a donor ( water ) to a primary electron acceptor, a quinone designated as q. in the second stage, electrons move from the quinone primary electron acceptor through a series of electron carriers until they reach a final electron acceptor, which is usually the oxidized form of nadp +, which is reduced to nadph, a process that takes place in a protein complex called photosystem i ( psi ). the transport of electrons is coupled to the movement of protons ( or hydrogen ) from the stroma to the thylakoid membrane, which forms a ph gradient across the membrane as hydrogen becomes more concentrated in the lumen than in the stroma. this is analogous to the proton - motive force generated across the inner mitochondrial membrane in aerobic respiration. during the third stage of photosynthesis, the movement of protons down their concentration gradients from the thylakoid lumen to the stroma through the atp synthase is coupled to the synthesis of atp by that same atp synthase. the nadph and atps generated by the light - dependent reactions in the second and third stages, respectively, provide the energy and . additionally, there are more sophisticated vr systems being developed which allow the user to use their entire body in their recovery. it also has sophisticated sensors that would allow medical professionals to collect data on muscle engagement and tension. it uses electrical impedance tomography, a form of noninvasive imaging to view muscle usage. another concern is the lack of major funding by big companies and the government into the field. many of these vr sets are off the shelf items, and not properly made for medical use. external add - ones are usually 3d printed or made from spare parts from other electronics. this lack of support means that patients who want to try this method have to be technically savvy, which is unlikely as many ailments only appear later in life. additionally, certain parts of vr like haptic feedback and tracking are still not advanced enough to be used reliably in a medical setting. another issue is the amount of vr devices that are available for purchase. while this does increase the options available, the differences between vr systems could impact patient recovery. the vast number of vr devices also makes it difficult for medical professionals to give and interpret information, as they might not have had practice with the specific model, which could lead to faulty advice being given out. = = = applications = = = currently other applications within healthcare are being explored, such as : applications for monitoring of glucose, alcohol, and lactate or blood oxygen, breath monitoring, heartbeat, heart rate and its variability, electromyography ( emg ), electrocardiogram ( ecg ) and electroencephalogram ( eeg ), body temperature, pressure ( e. g. in shoes ), sweat rate or sweat loss, levels of uric acid and ions – e. g. for preventing fatigue or injuries or for optimizing training patterns, including via " human - integrated electronics " forecasting changes in mood, stress, and health measuring blood alcohol content measuring athletic performance monitoring how sick the user is detecting early signs of infection long - term monitoring of patients with heart and circulatory problems that records an electrocardiogram and is self - moistening health risk assessment applications, including measures of frailty and risks of age - dependent diseases automatic documentation of care activities days - long continuous imaging of diverse organs via a wearable bioadhesive stretchable high - resolution ultrasound imaging patch or e. g. a wearable continuous heart ultrasound imager. ( potential novel diagnostic and monitoring tools ) sleep tracking cortisol monitoring for measuring stress measuring relaxation or alert general modes : static failure, and fatigue failure. static structural failure occurs when, upon being loaded ( having a force applied ) the object being analyzed either breaks or is deformed plastically, depending on the criterion for failure. fatigue failure occurs when an object fails after a number of repeated loading and unloading cycles. fatigue failure occurs because of imperfections in the object : a microscopic crack on the surface of the object, for instance, will grow slightly with each cycle ( propagation ) until the crack is large enough to cause ultimate failure. failure is not simply defined as when a part breaks, however ; it is defined as when a part does not operate as intended. some systems, such as the perforated top sections of some plastic bags, are designed to break. if these systems do not break, failure analysis might be employed to determine the cause. structural analysis is often used by mechanical engineers after a failure has occurred, or when designing to prevent failure. engineers often use online documents and books such as those published by asm to aid them in determining the type of failure and possible causes. once theory is applied to a mechanical design, physical testing is often performed to verify calculated results. structural analysis may be used in an office when designing parts, in the field to analyze failed parts, or in laboratories where parts might undergo controlled failure tests. = = = thermodynamics and thermo - science = = = thermodynamics is an applied science used in several branches of engineering, including mechanical and chemical engineering. at its simplest, thermodynamics is the study of energy, its use and transformation through a system. typically, engineering thermodynamics is concerned with changing energy from one form to another. as an example, automotive engines convert chemical energy ( enthalpy ) from the fuel into heat, and then into mechanical work that eventually turns the wheels. thermodynamics principles are used by mechanical engineers in the fields of heat transfer, thermofluids, and energy conversion. mechanical engineers use thermo - science to design engines and power plants, heating, ventilation, and air - conditioning ( hvac ) systems, heat exchangers, heat sinks, radiators, refrigeration, insulation, and others. = = = design and drafting = = = drafting or technical drawing is the means by which mechanical engineers design products and create instructions for manufacturing parts. a technical drawing can be a computer model or hand - drawn schematic showing all the dimensions necessary to manufacture a from the proton motive force drives the enzyme atp synthase to synthesize more atps by phosphorylating adps. the transfer of electrons terminates with molecular oxygen being the final electron acceptor. if oxygen were not present, pyruvate would not be metabolized by cellular respiration but undergoes a process of fermentation. the pyruvate is not transported into the mitochondrion but remains in the cytoplasm, where it is converted to waste products that may be removed from the cell. this serves the purpose of oxidizing the electron carriers so that they can perform glycolysis again and removing the excess pyruvate. fermentation oxidizes nadh to nad + so it can be re - used in glycolysis. in the absence of oxygen, fermentation prevents the buildup of nadh in the cytoplasm and provides nad + for glycolysis. this waste product varies depending on the organism. in skeletal muscles, the waste product is lactic acid. this type of fermentation is called lactic acid fermentation. in strenuous exercise, when energy demands exceed energy supply, the respiratory chain cannot process all of the hydrogen atoms joined by nadh. during anaerobic glycolysis, nad + regenerates when pairs of hydrogen combine with pyruvate to form lactate. lactate formation is catalyzed by lactate dehydrogenase in a reversible reaction. lactate can also be used as an indirect precursor for liver glycogen. during recovery, when oxygen becomes available, nad + attaches to hydrogen from lactate to form atp. in yeast, the waste products are ethanol and carbon dioxide. this type of fermentation is known as alcoholic or ethanol fermentation. the atp generated in this process is made by substrate - level phosphorylation, which does not require oxygen. = = = photosynthesis = = = photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that can later be released to fuel the organism ' s metabolic activities via cellular respiration. this chemical energy is stored in carbohydrate molecules, such as sugars, which are synthesized from carbon dioxide and water. in most cases, oxygen is released as a waste product. most plants, algae, and cyanobacteria perform photosynthesis, which is largely responsible for producing and maintaining the oxygen content of ##tronics, the science of using mechanical devices with human muscular, musculoskeletal, and nervous systems to assist or enhance motor control lost by trauma, disease, or defect. prostheses are typically used to replace parts lost by injury ( traumatic ) or missing from birth ( congenital ) or to supplement defective body parts. inside the body, artificial heart valves are in common use with artificial hearts and lungs seeing less common use but under active technology development. other medical devices and aids that can be considered prosthetics include hearing aids, artificial eyes, palatal obturator, gastric bands, and dentures. prostheses are specifically not orthoses, although given certain circumstances a prosthesis might end up performing some or all of the same functionary benefits as an orthosis. prostheses are technically the complete finished item. for instance, a c - leg knee alone is not a prosthesis, but only a prosthetic component. the complete prosthesis would consist of the attachment system to the residual limb – usually a " socket ", and all the attachment hardware components all the way down to and including the terminal device. despite the technical difference, the terms are often used interchangeably. the terms " prosthetic " and " orthotic " are adjectives used to describe devices such as a prosthetic knee. the terms " prosthetics " and " orthotics " are used to describe the respective allied health fields. an occupational therapist ' s role in prosthetics include therapy, training and evaluations. prosthetic training includes orientation to prosthetics components and terminology, donning and doffing, wearing schedule, and how to care for residual limb and the prosthesis. = = = exoskeletons = = = a powered exoskeleton is a wearable mobile machine that is powered by a system of electric motors, pneumatics, levers, hydraulics, or a combination of technologies that allow for limb movement with increased strength and endurance. its design aims to provide back support, sense the user ' s motion, and send a signal to motors which manage the gears. the exoskeleton supports the shoulder, waist and thigh, and assists movement for lifting and holding heavy items, while lowering back stress. = = = adaptive seating and positioning = = = people with balance and motor function challenges often need specialized equipment to sit or stand safely and securely. this equipment is frequently some references for the breaking strength of fused silica fibers compiled in 1999. is also higher at high temperature, as shown by carnot ' s theorem. in a conventional metallic engine, much of the energy released from the fuel must be dissipated as waste heat in order to prevent a meltdown of the metallic parts. despite all of these desirable properties, such engines are not in production because the manufacturing of ceramic parts in the requisite precision and durability is difficult. imperfection in the ceramic leads to cracks, which can lead to potentially dangerous equipment failure. such engines are possible in laboratory settings, but mass - production is not feasible with current technology. work is being done in developing ceramic parts for gas turbine engines. currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemical Question: What is common in muscles that have become exhausted by use? A) clumps acid fermentation B) Blood Acid Fermentation C) lactic acid fermentation D) vibration acid fermentation	C) lactic acid fermentation
Context: pigmentation, chloroplast structure and nutrient reserves. the algal division charophyta, sister to the green algal division chlorophyta, is considered to contain the ancestor of true plants. the charophyte class charophyceae and the land plant sub - kingdom embryophyta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form ##ta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xylem and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. hetero diploid embryo sporophyte within its tissues for at least part of its life, even in the seed plants, where the gametophyte itself is nurtured by its parent sporophyte. other groups of organisms that were previously studied by botanists include bacteria ( now studied in bacteriology ), fungi ( mycology ) – including lichen - forming fungi ( lichenology ), non - chlorophyte algae ( phycology ), and viruses ( virology ). however, attention is still given to these groups by botanists, and fungi ( including lichens ) and photosynthetic protists are usually covered in introductory botany courses. palaeobotanists study ancient plants in the fossil record to provide information about the evolutionary history of plants. cyanobacteria, the first oxygen - releasing photosynthetic organisms on earth, are thought to have given rise to the ancestor of plants by entering into an endosymbiotic relationship with an early eukaryote, ultimately becoming the chloroplasts in plant cells. the new photosynthetic plants ( along with their algal relatives ) accelerated the rise in atmospheric oxygen started by the cyanobacteria, changing the ancient oxygen - free, reducing, atmosphere to one in which free oxygen has been abundant for more than 2 billion years. among the important botanical questions of the 21st century are the role of plants as primary producers in the global cycling of life ' s basic ingredients : energy, carbon, oxygen, nitrogen and water, and ways that our plant stewardship can help address the global environmental issues of resource management, conservation, human food security, biologically invasive organisms, carbon sequestration, climate change, and sustainability. = = = human nutrition = = = virtually all staple foods come either directly from primary production by plants, or indirectly from animals that eat them. plants and other photosynthetic organisms are at the base of most food chains because they use the energy from the sun and nutrients from the soil and atmosphere, converting them into a form that can be used by animals. this is what ecologists call the first trophic level. the modern forms of the major staple foods, such as hemp, teff, maize, rice, wheat and other cereal grasses, pulses, bananas and plantains, as well as hemp, flax and cotton grown for their fibres, are the outcome of prehistoric selection over thousands of years from among wild ancestral plants with the most they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea conditions of early earth, thus suggesting that complex organic molecules could have arisen spontaneously in early earth ( see abiogenesis ). = = = macromolecules = = = macromolecules are large molecules made up of smaller subunits or monomers. monomers include sugars, amino acids, and nucleotides. carbohydrates include monomers and polymers of sugars. lipids are the only class of macromolecules that are not made up of polymers. they include steroids, phospholipids, and fats, largely nonpolar and hydrophobic ( water - repelling ) substances. proteins are the most diverse of the macromolecules. they include enzymes, transport proteins, large signaling molecules, antibodies, and structural proteins. the basic unit ( or monomer ) of a protein is an amino acid. twenty amino acids are used in proteins. nucleic acids are polymers of nucleotides. their function is to store, transmit, and express hereditary information. = = cells = = cell theory states that cells are the fundamental units of life, that all living things are composed of one or more cells, and that all cells arise from preexisting cells through cell division. most cells are very small, with diameters ranging from 1 to 100 micrometers and are therefore only visible under a light or electron microscope. there are generally two types of cells : eukaryotic cells, which contain a nucleus, and prokaryotic cells, which do not. prokaryotes are single - celled organisms such as bacteria, whereas eukaryotes can be single - celled or multicellular. in multicellular organisms, every cell in the organism ' s body is derived ultimately from a single cell in a fertilized egg. = = = cell structure = = = every cell is enclosed within a cell membrane that separates its cytoplasm from the extracellular space. a cell membrane consists of a lipid bilayer, including cholesterols that sit between phospholipids to maintain their fluidity at various temperatures. cell membranes are semipermeable, allowing small molecules such as oxygen, carbon dioxide, and water to pass through while restricting the movement of larger molecules and charged particles such as ions. cell membranes also contain membrane proteins, including integral membrane proteins that go across the membrane serving as membrane transporters, and peripheral proteins that loosely attach to the outer side of the cell membrane, acting as enzymes , and finally large gunpowder - propelled arrows and rocket weaponry. : 220 – 221 eventually, perishable bamboo was replaced with hollow tubes of cast iron, and so too did the terminology of this new weapon change, from ' fire - spear ' huo qiang to ' fire - tube ' huo tong. : 221 this ancestor to the gun was complemented by the ancestor to the cannon, what the chinese referred to since the 13th century as the ' multiple bullets magazine erupter ' bai zu lian zhu pao, a tube of bronze or cast iron that was filled with about 100 lead balls. : 263 – 264 the earliest known depiction of a gun is a sculpture from a cave in sichuan, dating to 1128, that portrays a figure carrying a vase - shaped bombard, firing flames and a cannonball. however, the oldest existent archaeological discovery of a metal barrel handgun is from the chinese heilongjiang excavation, dated to 1288. : 293 the chinese also discovered the explosive potential of packing hollowed cannonball shells with gunpowder. written later by jiao yu in his huolongjing ( mid - 14th century ), this manuscript recorded an earlier song - era cast - iron cannon known as the ' flying - cloud thunderclap eruptor ' ( fei yun pi - li pao ). the manuscript stated that : as noted before, the change in terminology for these new weapons during the song period were gradual. the early song cannons were at first termed the same way as the chinese trebuchet catapult. a later ming dynasty scholar known as mao yuanyi would explain this use of terminology and true origins of the cannon in his text of the wubei zhi, written in 1628 : the 14th - century huolongjing was also one of the first chinese texts to carefully describe to the use of explosive land mines, which had been used by the late song chinese against the mongols in 1277, and employed by the yuan dynasty afterwards. the innovation of the detonated land mine was accredited to one luo qianxia in the campaign of defense against the mongol invasion by kublai khan, : 192 later chinese texts revealed that the chinese land mine employed either a rip cord or a motion booby trap of a pin releasing falling weights that rotated a steel flint wheel, which in turn created sparks that ignited the train of fuses for the land mines. : 199 furthermore, the song employed the earliest known gunpowder - propelled rockets in warfare during the late 13th century, : 477 its earliest form being the bachelor of engineering ( b. eng. or b. e., depending on the institution ) ; the baccalaureat en genie ( b. ing., the french equivalent of a b. eng. ; sometimes referred to as a baccalaureat en ingenierie ) ; the bachelor of applied science ( b. a. sc. ) ; and the bachelor of science in engineering ( b. sc. eng. ). the canadian engineering accreditation board ( ceab ), a division of the engineers canada, sets out and maintains the standards of accreditation among canadian undergraduate engineering programs. graduates of those programs are deemed by the profession to have the required academic qualifications to be licensed as professional engineers in canada. this practice is intended to maintain standards of education and allow mobility of engineers in different provinces of canada. a ceab - accredited degree is the minimum academic requirement for registration as a professional engineer anywhere in the country and the standard against which all other engineering academic qualifications are measured. graduation from an accredited program, which normally involves four years of study, is a required first step to becoming a professional engineer. regulation and accreditation are accomplished through a self - governing body ( the name of which varies from province to province ), which is given the power by statute to register and discipline engineers, as well as regulate the field of engineering in the individual provinces. graduates of non - ceab - accredited programs must demonstrate that their education is at least equivalent to that of a graduate of a ceab - accredited program. = = = nigeria = = = in nigeria, the bachelor of engineering ( b. eng ) is a five year undergraduate professional degree course. the title of " engineer " or " engr " is protected in nigeria, making it impossible for any one to be addressed officially as one, if not a certified engineer. certification comes with registration and accreditation by council for the regulation of engineering in nigeria ( coren ). it is the regulatory body that governs the practice of engineering in nigeria. the membership is required to practice engineering independently. it is a requirement for some engineering firms and is mandatory for government contracts. = = see also = = bachelor ' s degree bachelor of technology bachelor of applied technology bachelor of science bachelor of applied science bachelor of science in information technology engineer ' s degree master ' s degree master of engineering master of science in engineering master of science master of applied science master of science in information technology institute of technology vocational university polytechnic ( greece ) polytechnic ( portugal ) polytechnic ( united kingdom ) = = references = = ##m and phloem that reproduced by spores germinating into free - living gametophytes evolved during the silurian period and diversified into several lineages during the late silurian and early devonian. representatives of the lycopods have survived to the present day. by the end of the devonian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to described as having homologous features ( or synapomorphy ). phylogeny provides the basis of biological classification. this classification system is rank - based, with the highest rank being the domain followed by kingdom, phylum, class, order, family, genus, and species. all organisms can be classified as belonging to one of three domains : archaea ( originally archaebacteria ), bacteria ( originally eubacteria ), or eukarya ( includes the fungi, plant, and animal kingdoms ). = = = history of life = = = the history of life on earth traces how organisms have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests be classified as belonging to one of three domains : archaea ( originally archaebacteria ), bacteria ( originally eubacteria ), or eukarya ( includes the fungi, plant, and animal kingdoms ). = = = history of life = = = the history of life on earth traces how organisms have evolved from the earliest emergence of life to present day. earth formed about 4. 5 billion years ago and all life on earth, both living and extinct, descended from a last universal common ancestor that lived about 3. 5 billion years ago. geologists have developed a geologic time scale that divides the history of the earth into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event Question: What is another term for the early larval stage of a frog? A) ovary B) tadpole C) egg D) young	B) tadpole
Context: the hun tian theory ), or as being without substance while the heavenly bodies float freely ( the hsuan yeh theory ), the earth was at all times flat, although perhaps bulging up slightly. the model of an egg was often used by chinese astronomers such as zhang heng ( 78 – 139 ad ) to describe the heavens as spherical : the heavens are like a hen ' s egg and as round as a crossbow bullet ; the earth is like the yolk of the egg, and lies in the centre. this analogy with a curved egg led some modern historians, notably joseph needham, to conjecture that chinese astronomers were, after all, aware of the earth ' s sphericity. the egg reference, however, was rather meant to clarify the relative position of the flat earth to the heavens : in a passage of zhang heng ' s cosmogony not translated by needham, zhang himself says : " heaven takes its body from the yang, so it is round and in motion. earth takes its body from the yin, so it is flat and quiescent ". the point of the egg analogy is simply to stress that the earth is completely enclosed by heaven, rather than merely covered from above as the kai tian describes. chinese astronomers, many of them brilliant men by any standards, continued to think in flat - earth terms until the seventeenth century ; this surprising fact might be the starting - point for a re - examination of the apparent facility with which the idea of a spherical earth found acceptance in fifth - century bc greece. further examples cited by needham supposed to demonstrate dissenting voices from the ancient chinese consensus actually refer without exception to the earth being square, not to it being flat. accordingly, the 13th - century scholar li ye, who argued that the movements of the round heaven would be hindered by a square earth, did not advocate a spherical earth, but rather that its edge should be rounded off so as to be circular. however, needham disagrees, affirming that li ye believed the earth to be spherical, similar in shape to the heavens but much smaller. this was preconceived by the 4th - century scholar yu xi, who argued for the infinity of outer space surrounding the earth and that the latter could be either square or round, in accordance to the shape of the heavens. when chinese geographers of the 17th century, influenced by european cartography and astronomy, showed the earth as a sphere that could be circumnavigated by sailing around the globe, they ##ian period, several groups, including the lycopods, sphenophylls and progymnosperms, had independently evolved " megaspory " – their spores were of two distinct sizes, larger megaspores and smaller microspores. their reduced gametophytes developed from megaspores retained within the spore - producing organs ( megasporangia ) of the sporophyte, a condition known as endospory. seeds consist of an endosporic megasporangium surrounded by one or two sheathing layers ( integuments ). the young sporophyte develops within the seed, which on germination splits to release it. the earliest known seed plants date from the latest devonian famennian stage. following the evolution of the seed habit, seed plants diversified, giving rise to a number of now - extinct groups, including seed ferns, as well as the modern gymnosperms and angiosperms. gymnosperms produce " naked seeds " not fully enclosed in an ovary ; modern representatives include conifers, cycads, ginkgo, and gnetales. angiosperms produce seeds enclosed in a structure such as a carpel or an ovary. ongoing research on the molecular phylogenetics of living plants appears to show that the angiosperms are a sister clade to the gymnosperms. = = plant physiology = = plant physiology encompasses all the internal chemical and physical activities of plants associated with life. chemicals obtained from the air, soil and water form the basis of all plant metabolism. the energy of sunlight, captured by oxygenic photosynthesis and released by cellular respiration, is the basis of almost all life. photoautotrophs, including all green plants, algae and cyanobacteria gather energy directly from sunlight by photosynthesis. heterotrophs including all animals, all fungi, all completely parasitic plants, and non - photosynthetic bacteria take in organic molecules produced by photoautotrophs and respire them or use them in the construction of cells and tissues. respiration is the oxidation of carbon compounds by breaking them down into simpler structures to release the energy they contain, essentially the opposite of photosynthesis. molecules are moved within plants by transport processes that operate at a variety of spatial scales. subcellular transport of ions, electrons and molecules such as water and enzymes occurs across cell membranes. minerals and water are transported from roots to other parts of the plant in if a fintie group g acts topologically and faithfully on r ^ 3, then g is a subgroup of o ( 3 ) offended athenian audiences ; in this play, he speculated that the titular sorceress medea killed her own children, as opposed to their being killed by other corinthians after her departure. in historiography, what is now called speculative fiction has previously been termed historical invention, historical fiction, and similar names. these terms have been extensively applied in literary criticism to the works of william shakespeare. for example, in a midsummer night ' s dream, he places several characters from different locations and times into the fairyland of the fictional merovingian germanic sovereign oberon ; these characters include the athenian duke theseus, the amazonian queen hippolyta, the english fairy puck, and the roman god cupid. in mythography, the concept of speculative fiction has been termed mythopoesis or mythopoeia. this process involves the creative design and development of lore and mythology for works of fiction. the term ' s definition comes from use by j. r. r. tolkien ; his series of novels, the lord of the rings, shows an application of the process. themes common in mythopoeia, such as the supernatural, alternate history, and sexuality, continue to be explored in works produced in modern speculative fiction. speculative fiction in the general sense of hypothetical history, explanation, or ahistorical storytelling has been attributed to authors in ostensibly non - fiction modes since herodotus of halicarnassus ( fl. 5th century bce ) with his histories ; it was already both created and edited out by early encyclopedic writers such sima qian ( c. 145 or 135 bce – 86 bce ), author of shiji. these examples highlight a caveat — many works that are now viewed as speculative fiction long predated the labelling of the genre. in the broadest sense, the genre ' s concept does two things : it captures both conscious and unconscious aspects of human psychology in making sense of the world, and it responds to the world by creating imaginative, inventive, and artistic expressions. such expressions can contribute to practical societal progress through interpersonal influences ; social and cultural movements ; scientific research and advances ; and the philosophy of science. in english - language usage in arts and literature since the mid 20th century, the term speculative fiction has often been attributed to robert a. heinlein, who first used it in an editorial in the saturday evening post ( on 8 february 1947 ). in the article, heinlein used speculative fiction as a synonym for science fiction ; in describe the heavens as spherical : the heavens are like a hen ' s egg and as round as a crossbow bullet ; the earth is like the yolk of the egg, and lies in the centre. this analogy with a curved egg led some modern historians, notably joseph needham, to conjecture that chinese astronomers were, after all, aware of the earth ' s sphericity. the egg reference, however, was rather meant to clarify the relative position of the flat earth to the heavens : in a passage of zhang heng ' s cosmogony not translated by needham, zhang himself says : " heaven takes its body from the yang, so it is round and in motion. earth takes its body from the yin, so it is flat and quiescent ". the point of the egg analogy is simply to stress that the earth is completely enclosed by heaven, rather than merely covered from above as the kai tian describes. chinese astronomers, many of them brilliant men by any standards, continued to think in flat - earth terms until the seventeenth century ; this surprising fact might be the starting - point for a re - examination of the apparent facility with which the idea of a spherical earth found acceptance in fifth - century bc greece. further examples cited by needham supposed to demonstrate dissenting voices from the ancient chinese consensus actually refer without exception to the earth being square, not to it being flat. accordingly, the 13th - century scholar li ye, who argued that the movements of the round heaven would be hindered by a square earth, did not advocate a spherical earth, but rather that its edge should be rounded off so as to be circular. however, needham disagrees, affirming that li ye believed the earth to be spherical, similar in shape to the heavens but much smaller. this was preconceived by the 4th - century scholar yu xi, who argued for the infinity of outer space surrounding the earth and that the latter could be either square or round, in accordance to the shape of the heavens. when chinese geographers of the 17th century, influenced by european cartography and astronomy, showed the earth as a sphere that could be circumnavigated by sailing around the globe, they did so with formulaic terminology previously used by zhang heng to describe the spherical shape of the sun and moon ( i. e. that they were as round as a crossbow bullet ). as noted in the book huainanzi, in the 2nd century bc, chinese astronomers effectively inverted eratosthenes ' calculation of these cellular components. the different stages of mitosis all together define the mitotic phase of an animal cell cycle — the division of the mother cell into two genetically identical daughter cells. the cell cycle is a vital process by which a single - celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. after cell division, each of the daughter cells begin the interphase of a new cycle. in contrast to mitosis, meiosis results in four haploid daughter cells by undergoing one round of dna replication followed by two divisions. homologous chromosomes are separated in the first division ( meiosis i ), and sister chromatids are separated in the second division ( meiosis ii ). both of these cell division cycles are used in the process of sexual reproduction at some point in their life cycle. both are believed to be present in the last eukaryotic common ancestor. prokaryotes ( i. e., archaea and bacteria ) can also undergo cell division ( or binary fission ). unlike the processes of mitosis and meiosis in eukaryotes, binary fission in prokaryotes takes place without the formation of a spindle apparatus on the cell. before binary fission, dna in the bacterium is tightly coiled. after it has uncoiled and duplicated, it is pulled to the separate poles of the bacterium as it increases the size to prepare for splitting. growth of a new cell wall begins to separate the bacterium ( triggered by ftsz polymerization and " z - ring " formation ). the new cell wall ( septum ) fully develops, resulting in the complete split of the bacterium. the new daughter cells have tightly coiled dna rods, ribosomes, and plasmids. = = = sexual reproduction and meiosis = = = meiosis is a central feature of sexual reproduction in eukaryotes, and the most fundamental function of meiosis appears to be conservation of the integrity of the genome that is passed on to progeny by parents. two aspects of sexual reproduction, meiotic recombination and outcrossing, are likely maintained respectively by the adaptive advantages of recombinational repair of genomic dna damage and genetic complementation which masks the expression of deleterious recessive mutations. the beneficial effect of genetic complementation, derived from outcrossing ( cross - fertilization ) is also referred to as hybrid vigor or heterosis. charles the paper is withdrawn by the author because it is superseded by cond - mat / 0303357. ##tase, human chorionic gonadotrophin, α - fetoprotein and others are organ - associated antigens and the production of monoclonal antibodies against these antigens helps in determining the nature of a primary tumor. monoclonal antibodies are especially useful in distinguishing morphologically similar lesions, like pleural and peritoneal mesothelioma, adenocarcinoma, and in the determination of the organ or tissue origin of undifferentiated metastases. selected monoclonal antibodies help in the detection of occult metastases ( cancer of unknown primary origin ) by immuno - cytological analysis of bone marrow, other tissue aspirates, as well as lymph nodes and other tissues and can have increased sensitivity over normal histopathological staining. one study performed a sensitive immuno - histochemical assay on bone marrow aspirates of 20 patients with localized prostate cancer. three monoclonal antibodies ( t16, c26, and ae - 1 ), capable of recognizing membrane and cytoskeletal antigens expressed by epithelial cells to detect tumour cells, were used in the assay. bone marrow aspirates of 22 % of patients with localized prostate cancer ( stage b, 0 / 5 ; stage c, 2 / 4 ), and 36 % patients with metastatic prostate cancer ( stage d1, 0 / 7 patients ; stage d2, 4 / 4 patients ) had antigen - positive cells in their bone marrow. it was concluded that immuno - histochemical staining of bone marrow aspirates are very useful to detect occult bone marrow metastases in patients with apparently localized prostate cancer. although immuno - cytochemistry using tumor - associated monoclonal antibodies has led to an improved ability to detect occult breast cancer cells in bone marrow aspirates and peripheral blood, further development of this method is necessary before it can be used routinely. one major drawback of immuno - cytochemistry is that only tumor - associated and not tumor - specific monoclonal antibodies are used, and as a result, some cross - reaction with normal cells can occur. in order to effectively stage breast cancer and assess the efficacy of purging regimens prior to autologous stem cell infusion, it is important to detect even small quantities of breast cancer cells. immuno - histochemical methods are ideal for this purpose because they are simple, sensitive, and quite specific in mathematics, a projection is an idempotent mapping of a set ( or other mathematical structure ) into a subset ( or sub - structure ). in this case, idempotent means that projecting twice is the same as projecting once. the restriction to a subspace of a projection is also called a projection, even if the idempotence property is lost. an everyday example of a projection is the casting of shadows onto a plane ( sheet of paper ) : the projection of a point is its shadow on the sheet of paper, and the projection ( shadow ) of a point on the sheet of paper is that point itself ( idempotency ). the shadow of a three - dimensional sphere is a disk. originally, the notion of projection was introduced in euclidean geometry to denote the projection of the three - dimensional euclidean space onto a plane in it, like the shadow example. the two main projections of this kind are : the projection from a point onto a plane or central projection : if c is a point, called the center of projection, then the projection of a point p different from c onto a plane that does not contain c is the intersection of the line cp with the plane. the points p such that the line cp is parallel to the plane does not have any image by the projection, but one often says that they project to a point at infinity of the plane ( see projective geometry for a formalization of this terminology ). the projection of the point c itself is not defined. the projection parallel to a direction d, onto a plane or parallel projection : the image of a point p is the intersection of the plane with the line parallel to d passing through p. see affine space § projection for an accurate definition, generalized to any dimension. the concept of projection in mathematics is a very old one, and most likely has its roots in the phenomenon of the shadows cast by real - world objects on the ground. this rudimentary idea was refined and abstracted, first in a geometric context and later in other branches of mathematics. over time different versions of the concept developed, but today, in a sufficiently abstract setting, we can unify these variations. in cartography, a map projection is a map of a part of the surface of the earth onto a plane, which, in some cases, but not always, is the restriction of a projection in the above meaning. the 3d projections are also at the basis of the theory of perspective. the need for unifying the two kinds of projections and of defining the image this article is withdrawn because of a mistake in the main result of the paper. Question: The release of an egg from an ovary, is part of what cycle? A) stomach B) menstrual C) life D) fetal	B) menstrual
Context: ) : the reason for the current medical visit. these are the symptoms. they are in the patient ' s own words and are recorded along with the duration of each one. also called chief concern or presenting complaint. current activity : occupation, hobbies, what the patient actually does. family history ( fh ) : listing of diseases in the family that may impact the patient. a family tree is sometimes used. history of present illness ( hpi ) : the chronological order of events of symptoms and further clarification of each symptom. distinguishable from history of previous illness, often called past medical history ( pmh ). medical history comprises hpi and pmh. medications ( rx ) : what drugs the patient takes including prescribed, over - the - counter, and home remedies, as well as alternative and herbal medicines or remedies. allergies are also recorded. past medical history ( pmh / pmhx ) : concurrent medical problems, past hospitalizations and operations, injuries, past infectious diseases or vaccinations, history of known allergies. review of systems ( ros ) or systems inquiry : a set of additional questions to ask, which may be missed on hpi : a general enquiry ( have you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, the hun tian theory ), or as being without substance while the heavenly bodies float freely ( the hsuan yeh theory ), the earth was at all times flat, although perhaps bulging up slightly. the model of an egg was often used by chinese astronomers such as zhang heng ( 78 – 139 ad ) to describe the heavens as spherical : the heavens are like a hen ' s egg and as round as a crossbow bullet ; the earth is like the yolk of the egg, and lies in the centre. this analogy with a curved egg led some modern historians, notably joseph needham, to conjecture that chinese astronomers were, after all, aware of the earth ' s sphericity. the egg reference, however, was rather meant to clarify the relative position of the flat earth to the heavens : in a passage of zhang heng ' s cosmogony not translated by needham, zhang himself says : " heaven takes its body from the yang, so it is round and in motion. earth takes its body from the yin, so it is flat and quiescent ". the point of the egg analogy is simply to stress that the earth is completely enclosed by heaven, rather than merely covered from above as the kai tian describes. chinese astronomers, many of them brilliant men by any standards, continued to think in flat - earth terms until the seventeenth century ; this surprising fact might be the starting - point for a re - examination of the apparent facility with which the idea of a spherical earth found acceptance in fifth - century bc greece. further examples cited by needham supposed to demonstrate dissenting voices from the ancient chinese consensus actually refer without exception to the earth being square, not to it being flat. accordingly, the 13th - century scholar li ye, who argued that the movements of the round heaven would be hindered by a square earth, did not advocate a spherical earth, but rather that its edge should be rounded off so as to be circular. however, needham disagrees, affirming that li ye believed the earth to be spherical, similar in shape to the heavens but much smaller. this was preconceived by the 4th - century scholar yu xi, who argued for the infinity of outer space surrounding the earth and that the latter could be either square or round, in accordance to the shape of the heavens. when chinese geographers of the 17th century, influenced by european cartography and astronomy, showed the earth as a sphere that could be circumnavigated by sailing around the globe, they describe the heavens as spherical : the heavens are like a hen ' s egg and as round as a crossbow bullet ; the earth is like the yolk of the egg, and lies in the centre. this analogy with a curved egg led some modern historians, notably joseph needham, to conjecture that chinese astronomers were, after all, aware of the earth ' s sphericity. the egg reference, however, was rather meant to clarify the relative position of the flat earth to the heavens : in a passage of zhang heng ' s cosmogony not translated by needham, zhang himself says : " heaven takes its body from the yang, so it is round and in motion. earth takes its body from the yin, so it is flat and quiescent ". the point of the egg analogy is simply to stress that the earth is completely enclosed by heaven, rather than merely covered from above as the kai tian describes. chinese astronomers, many of them brilliant men by any standards, continued to think in flat - earth terms until the seventeenth century ; this surprising fact might be the starting - point for a re - examination of the apparent facility with which the idea of a spherical earth found acceptance in fifth - century bc greece. further examples cited by needham supposed to demonstrate dissenting voices from the ancient chinese consensus actually refer without exception to the earth being square, not to it being flat. accordingly, the 13th - century scholar li ye, who argued that the movements of the round heaven would be hindered by a square earth, did not advocate a spherical earth, but rather that its edge should be rounded off so as to be circular. however, needham disagrees, affirming that li ye believed the earth to be spherical, similar in shape to the heavens but much smaller. this was preconceived by the 4th - century scholar yu xi, who argued for the infinity of outer space surrounding the earth and that the latter could be either square or round, in accordance to the shape of the heavens. when chinese geographers of the 17th century, influenced by european cartography and astronomy, showed the earth as a sphere that could be circumnavigated by sailing around the globe, they did so with formulaic terminology previously used by zhang heng to describe the spherical shape of the sun and moon ( i. e. that they were as round as a crossbow bullet ). as noted in the book huainanzi, in the 2nd century bc, chinese astronomers effectively inverted eratosthenes ' calculation diagnosis and management of hereditary disorders. neurology is concerned with diseases of the nervous system. in the uk, neurology is a subspecialty of general medicine. obstetrics and gynecology ( often abbreviated as ob / gyn ( american english ) or obs & gynae ( british english ) ) are concerned respectively with childbirth and the female reproductive and associated organs. reproductive medicine and fertility medicine are generally practiced by gynecological specialists. pediatrics ( ae ) or paediatrics ( be ) is devoted to the care of infants, children, and adolescents. like internal medicine, there are many pediatric subspecialties for specific age ranges, organ systems, disease classes, and sites of care delivery. pharmaceutical medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of marketing of medicines for the benefit of patients and public health. physical medicine and rehabilitation ( or physiatry ) is concerned with functional improvement after injury, illness, or congenital disorders. podiatric medicine is the study of, diagnosis, and medical and surgical treatment of disorders of the foot, ankle, lower limb, hip and lower back. preventive medicine is the branch of medicine concerned with preventing disease. community health or public health is an aspect of health services concerned with threats to the overall health of a community based on population health analysis. psychiatry is the branch of medicine concerned with the bio - psycho - social study of the etiology, diagnosis, treatment and prevention of cognitive, perceptual, emotional and behavioral disorders. related fields include psychotherapy and clinical psychology. = = = interdisciplinary fields = = = some interdisciplinary sub - specialties of medicine include : addiction medicine deals with the treatment of addiction. aerospace medicine deals with medical problems related to flying and space travel. biomedical engineering is a field dealing with the application of engineering principles to medical practice. clinical pharmacology is concerned with how systems of therapeutics interact with patients. conservation medicine studies the relationship between human and non - human animal health, and environmental conditions. also known as ecological medicine, environmental medicine, or medical geology. disaster medicine deals with medical aspects of emergency preparedness, disaster mitigation and management. diving medicine ( or hyperbaric medicine ) is the prevention and treatment of diving - related problems. evolutionary medicine is a perspective on medicine derived through applying evolutionary theory. forensic medicine deals with medical questions in legal context, such as determination of the time and cause of death, type of weapon used to inflict system ( sls ) that would also send an orion spacecraft on a distant retrograde orbit. the first tentative steps of returning to crewed lunar missions will be artemis ii, which is to include the orion crew module, propelled by the sls, and is expected to launch no later than april 2026. this mission is to be a 10 - day mission planned to briefly place a crew of four into a lunar flyby. artemis iii aims to conduct the first crewed lunar landing since apollo 17, and is scheduled for no earlier than mid - 2027. in support of the artemis missions, nasa has been funding private companies to land robotic probes on the lunar surface in a program known as the commercial lunar payload services. as of march 2022, nasa has awarded contracts for robotic lunar probes to companies such as intuitive machines, firefly space systems, and astrobotic. on april 16, 2021, nasa announced they had selected the spacex lunar starship as its human landing system. the agency ' s space launch system rocket will launch four astronauts aboard the orion spacecraft for their multi - day journey to lunar orbit where they will transfer to spacex ' s starship for the final leg of their journey to the surface of the moon. in november 2021, it was announced that the goal of landing astronauts on the moon by 2024 had slipped to no earlier than 2027 due to numerous factors. artemis i launched on november 16, 2022, and returned to earth safely on december 11, 2022. as of april 2025, nasa plans to launch artemis ii in april 2026. and artemis iii in 2027. additional artemis missions, artemis iv, artemis v, and artemis vi are planned to launch between 2028 and 2031. nasa ' s next major space initiative is the construction of the lunar gateway, a small space station in lunar orbit. this space station will be designed primarily for non - continuous human habitation. the construction of the gateway is expected to begin in 2027 with the launch of the first two modules : the power and propulsion element ( ppe ) and the habitation and logistics outpost ( halo ). operations on the gateway will begin with the artemis iv mission, which plans to deliver a crew of four to the gateway in 2028. in 2017, nasa was directed by the congressional nasa transition authorization act of 2017 to get humans to mars - orbit ( or to the martian surface ) by the 2030s. = = = = commercial leo development ( 2021 – present ) = = = = the commercial low river valley during ancient times. the papyrus was harvested by field workers and brought to processing centers where it was cut into thin strips. the strips were then laid - out side by side and covered in plant resin. the second layer of strips was laid on perpendicularly, then both pressed together until the sheet was dry. the sheets were then joined to form a roll and later used for writing. egyptian society made several significant advances during dynastic periods in many areas of technology. according to hossam elanzeery, they were the first civilization to use timekeeping devices such as sundials, shadow clocks, and obelisks and successfully leveraged their knowledge of astronomy to create a calendar model that society still uses today. they developed shipbuilding technology that saw them progress from papyrus reed vessels to cedar wood ships while also pioneering the use of rope trusses and stem - mounted rudders. the egyptians also used their knowledge of anatomy to lay the foundation for many modern medical techniques and practiced the earliest known version of neuroscience. elanzeery also states that they used and furthered mathematical science, as evidenced in the building of the pyramids. ancient egyptians also invented and pioneered many food technologies that have become the basis of modern food technology processes. based on paintings and reliefs found in tombs, as well as archaeological artifacts, scholars like paul t nicholson believe that the ancient egyptians established systematic farming practices, engaged in cereal processing, brewed beer and baked bread, processed meat, practiced viticulture and created the basis for modern wine production, and created condiments to complement, preserve and mask the flavors of their food. = = = = indus valley = = = = the indus valley civilization, situated in a resource - rich area ( in modern pakistan and northwestern india ), is notable for its early application of city planning, sanitation technologies, and plumbing. indus valley construction and architecture, called ' vaastu shastra ', suggests a thorough understanding of materials engineering, hydrology, and sanitation. = = = = china = = = = the chinese made many first - known discoveries and developments. major technological contributions from china include the earliest known form of the binary code and epigenetic sequencing, early seismological detectors, matches, paper, helicopter rotor, raised - relief map, the double - action piston pump, cast iron, water powered blast furnace bellows, the iron plough, the multi - tube seed drill, the wheelbarrow, the parachute, the compass, the rudder, the crossbow, the south pointing chariot and gunpowder practice, general practice or primary care is, in many countries, the first port - of - call for patients with non - emergency medical problems. family physicians often provide services across a broad range of settings including office based practices, emergency department coverage, inpatient care, and nursing home care. medical genetics is concerned with the diagnosis and management of hereditary disorders. neurology is concerned with diseases of the nervous system. in the uk, neurology is a subspecialty of general medicine. obstetrics and gynecology ( often abbreviated as ob / gyn ( american english ) or obs & gynae ( british english ) ) are concerned respectively with childbirth and the female reproductive and associated organs. reproductive medicine and fertility medicine are generally practiced by gynecological specialists. pediatrics ( ae ) or paediatrics ( be ) is devoted to the care of infants, children, and adolescents. like internal medicine, there are many pediatric subspecialties for specific age ranges, organ systems, disease classes, and sites of care delivery. pharmaceutical medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of marketing of medicines for the benefit of patients and public health. physical medicine and rehabilitation ( or physiatry ) is concerned with functional improvement after injury, illness, or congenital disorders. podiatric medicine is the study of, diagnosis, and medical and surgical treatment of disorders of the foot, ankle, lower limb, hip and lower back. preventive medicine is the branch of medicine concerned with preventing disease. community health or public health is an aspect of health services concerned with threats to the overall health of a community based on population health analysis. psychiatry is the branch of medicine concerned with the bio - psycho - social study of the etiology, diagnosis, treatment and prevention of cognitive, perceptual, emotional and behavioral disorders. related fields include psychotherapy and clinical psychology. = = = interdisciplinary fields = = = some interdisciplinary sub - specialties of medicine include : addiction medicine deals with the treatment of addiction. aerospace medicine deals with medical problems related to flying and space travel. biomedical engineering is a field dealing with the application of engineering principles to medical practice. clinical pharmacology is concerned with how systems of therapeutics interact with patients. conservation medicine studies the relationship between human and non - human animal health, and environmental conditions. also known as ecological medicine, environmental medicine, or medical geology. disaster medicine deals with medical aspects of emergency preparedness, disaster mitigation decision making during a task, and they provide us with some insight into the ways in which those decisions may be processed. = = = brain imaging = = = brain imaging involves analyzing activity within the brain while performing various tasks. this allows us to link behavior and brain function to help understand how information is processed. different types of imaging techniques vary in their temporal ( time - based ) and spatial ( location - based ) resolution. brain imaging is often used in cognitive neuroscience. single - photon emission computed tomography and positron emission tomography. spect and pet use radioactive isotopes, which are injected into the subject ' s bloodstream and taken up by the brain. by observing which areas of the brain take up the radioactive isotope, we can see which areas of the brain are more active than other areas. pet has similar spatial resolution to fmri, but it has extremely poor temporal resolution. electroencephalography. eeg measures the electrical fields generated by large populations of neurons in the cortex by placing a series of electrodes on the scalp of the subject. this technique has an extremely high temporal resolution, but a relatively poor spatial resolution. functional magnetic resonance imaging. fmri measures the relative amount of oxygenated blood flowing to different parts of the brain. more oxygenated blood in a particular region is assumed to correlate with an increase in neural activity in that part of the brain. this allows us to localize particular functions within different brain regions. fmri has moderate spatial and temporal resolution. optical imaging. this technique uses infrared transmitters and receivers to measure the amount of light reflectance by blood near different areas of the brain. since oxygenated and deoxygenated blood reflects light by different amounts, we can study which areas are more active ( i. e., those that have more oxygenated blood ). optical imaging has moderate temporal resolution, but poor spatial resolution. it also has the advantage that it is extremely safe and can be used to study infants ' brains. magnetoencephalography. meg measures magnetic fields resulting from cortical activity. it is similar to eeg, except that it has improved spatial resolution since the magnetic fields it measures are not as blurred or attenuated by the scalp, meninges and so forth as the electrical activity measured in eeg is. meg uses squid sensors to detect tiny magnetic fields. = = = computational modeling = = = computational models require a mathematically and logically formal representation of a problem. computer models are used in the simulation and experimental verification of different you noticed any weight loss, change in sleep quality, fevers, lumps and bumps? etc. ), followed by questions on the body ' s main organ systems ( heart, lungs, digestive tract, urinary tract, etc. ). social history ( sh ) : birthplace, residences, marital history, social and economic status, habits ( including diet, medications, tobacco, alcohol ). the physical examination is the examination of the patient for medical signs of disease that are objective and observable, in contrast to symptoms that are volunteered by the patient and are not necessarily objectively observable. the healthcare provider uses sight, hearing, touch, and sometimes smell ( e. g., in infection, uremia, diabetic ketoacidosis ). four actions are the basis of physical examination : inspection, palpation ( feel ), percussion ( tap to determine resonance characteristics ), and auscultation ( listen ), generally in that order, although auscultation occurs prior to percussion and palpation for abdominal assessments. the clinical examination involves the study of : abdomen and rectum cardiovascular ( heart and blood vessels ) general appearance of the patient and specific indicators of disease ( nutritional status, presence of jaundice, pallor or clubbing ) genitalia ( and pregnancy if the patient is or could be pregnant ) head, eye, ear, nose, and throat ( heent ) musculoskeletal ( including spine and extremities ) neurological ( consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves ) psychiatric ( orientation, mental state, mood, evidence of abnormal perception or thought ). respiratory ( large airways and lungs ) skin vital signs including height, weight, body temperature, blood pressure, pulse, respiration rate, and hemoglobin oxygen saturation it is to likely focus on areas of interest highlighted in the medical history and may not include everything listed above. the treatment plan may include ordering additional medical laboratory tests and medical imaging studies, starting therapy, referral to a specialist, or watchful observation. a follow - up may be advised. depending upon the health insurance plan and the managed care system, various forms of " utilization review ", such as prior authorization of tests, may place barriers on accessing expensive services. the medical decision - making ( mdm ) process includes the analysis and synthesis of all the above data to come up with a list of possible diagnoses ( the differential diagnoses ), an oscillation with a period of around 500 kb in guanine and cytosine content ( gc % ) is observed in the dna sequence of human chromosome 21. this oscillation is localized in the rightmost one - eighth region of the chromosome, from 43. 5 mb to 46. 5 mb. five cycles of oscillation are observed in this region with six gc - rich peaks and five gc - poor valleys. the gc - poor valleys comprise regions with low density of cpg islands and, alternating between the two dna strands, low gene density regions. consequently, the long - range oscillation of gc % result in spacing patterns of both cpg island density, and to a lesser extent, gene densities. Question: Which part of the body shows does horner's syndrome affect? A) the nose B) one eye C) the mouth D) the tongue	B) one eye
Context: parametric excitation of rotons by oscillating electric field exhibits a narrow resonance at the roton minimum frequency. the resonance width is in good agreement with experimental results on the microwave absorption in superfluid helium. new non - perturbatives excitations in the massless thirring and schwinger models are discussed. an oscillation with a period of around 500 kb in guanine and cytosine content ( gc % ) is observed in the dna sequence of human chromosome 21. this oscillation is localized in the rightmost one - eighth region of the chromosome, from 43. 5 mb to 46. 5 mb. five cycles of oscillation are observed in this region with six gc - rich peaks and five gc - poor valleys. the gc - poor valleys comprise regions with low density of cpg islands and, alternating between the two dna strands, low gene density regions. consequently, the long - range oscillation of gc % result in spacing patterns of both cpg island density, and to a lesser extent, gene densities. consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea. more than 6, 000 virus species have been described in detail. viruses are found in almost every ecosystem on earth and are the most numerous type of biological entity. the origins of viruses in the evolutionary history of life are unclear : some may have evolved from plasmids — pieces of dna that can move between cells — while others may have evolved from bacteria. in evolution, viruses are an important means of horizontal gene transfer, which increases genetic diversity in a way analogous to sexual reproduction. because viruses possess some but not all characteristics of life, they have been described as " organisms at the edge of life ", and as self - replicators. = = ecology = = ecology is the study of the distribution and abundance of life, the interaction between organisms and their environment. = = = ecosystems = = = the community of living ( biotic ) organisms in conjunction with the nonliving ( abiotic ) components ( e. g., water, light, radiation, temperature, humidity, atmosphere, acidity, and soil ) of their environment is called an ecosystem. these biotic and abiotic components are linked together through nutrient cycles and energy flows. energy from the sun enters the system through photosynthesis and is incorporated into plant tissue. by feeding on plants and on one another, animals move matter and energy through the system. they also influence the quantity of plant and microbial biomass present. by breaking down dead organic matter, decomposers release carbon back to the atmosphere and facilitate nutrient cycling by converting nutrients stored in dead biomass back to a form that can be readily used by plants and other microbes. = = = populations = = = a population is the group of organisms of the same species that occupies an area and reproduce from generation to generation. population size can be estimated by multiplying population density by the area or volume. the carrying capacity of an environment it is argued that two - particle collisions of relativistic particles " at a distance ", irrespective of their position in the configuration space, generate uniform distribution of particles in lorentz invariant phase space. various mechanisms of thermal photon production are reviewed and their implications for heavy ion collisions are briefly sketched. in his 1878 book the effects of cross and self - fertilization in the vegetable kingdom at the start of chapter xii noted " the first and most important of the conclusions which may be drawn from the observations given in this volume, is that generally cross - fertilisation is beneficial and self - fertilisation often injurious, at least with the plants on which i experimented. " an important adaptive benefit of outcrossing is that it allows the masking of deleterious mutations in the genome of progeny. this beneficial effect is also known as hybrid vigor or heterosis. once outcrossing is established, subsequent switching to inbreeding becomes disadvantageous since it allows expression of the previously masked deleterious recessive mutations, commonly referred to as inbreeding depression. unlike in higher animals, where parthenogenesis is rare, asexual reproduction may occur in plants by several different mechanisms. the formation of stem tubers in potato is one example. particularly in arctic or alpine habitats, where opportunities for fertilisation of flowers by animals are rare, plantlets or bulbs, may develop instead of flowers, replacing sexual reproduction with asexual reproduction and giving rise to clonal populations genetically identical to the parent. this is one of several types of apomixis that occur in plants. apomixis can also happen in a seed, producing a seed that contains an embryo genetically identical to the parent. most sexually reproducing organisms are diploid, with paired chromosomes, but doubling of their chromosome number may occur due to errors in cytokinesis. this can occur early in development to produce an autopolyploid or partly autopolyploid organism, or during normal processes of cellular differentiation to produce some cell types that are polyploid ( endopolyploidy ), or during gamete formation. an allopolyploid plant may result from a hybridisation event between two different species. both autopolyploid and allopolyploid plants can often reproduce normally, but may be unable to cross - breed successfully with the parent population because there is a mismatch in chromosome numbers. these plants that are reproductively isolated from the parent species but live within the same geographical area, may be sufficiently successful to form a new species. some otherwise sterile plant polyploids can still reproduce vegetatively or by seed apomixis, forming clonal populations of identical individuals. durum wheat is a fertile tetraploid allopolyploid an attempt had been made to get algebraic structure of 2d complex harmonic oscillator. it is a review of some results in odd symplectic geometry related to the batalin - vilkovisky formalism unitary recordings in freely - moving pulse weakly electric fish suggest spike timing encoding of electrosensory signals Question: In which way to vertebrates reproduces? A) biologically B) anally C) sexually D) asexually	C) sexually
Context: as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = = glass - ceramics = = glass - ceramic materials share many properties with both glasses and ceramics. glass - ceramics have an amorphous phase and one or more crystalline phases and are produced by a so - called " controlled crystallization ", which is typically avoided in glass manufacturing. glass - ceramics often contain a crystalline phase polymer diodes require cathodes that do not corrode the polymer but do have low work function to minimize the electron injection barrier. first - principles calculations demonstrate that the work function of the ( 1000 ) surface of the compound ca2n is half an ev lower than that of the elemental metal ca ( 2. 35 vs. 2. 87 ev ). moreover its reactivity is expected to be smaller. this makes ca2n an interesting candidate to replace calcium as cathode material for polymer light emitting diode devices. is called its bandwidth ( bw ). for any given signal - to - noise ratio, a given bandwidth can carry the same amount of information regardless of where in the radio frequency spectrum it is located ; bandwidth is a measure of information - carrying capacity. the bandwidth required by a radio transmission depends on the data rate of the information being sent, and the spectral efficiency of the modulation method used ; how much data it can transmit in each unit of bandwidth. different types of information signals carried by radio have different data rates. for example, a television signal has a greater data rate than an audio signal. the radio spectrum, the total range of radio frequencies that can be used for communication in a given area, is a limited resource. each radio transmission occupies a portion of the total bandwidth available. radio bandwidth is regarded as an economic good which has a monetary cost and is in increasing demand. in some parts of the radio spectrum, the right to use a frequency band or even a single radio channel is bought and sold for millions of dollars. so there is an incentive to employ technology to minimize the bandwidth used by radio services. a slow transition from analog to digital radio transmission technologies began in the late 1990s. part of the reason for this is that digital modulation can often transmit more information ( a greater data rate ) in a given bandwidth than analog modulation, by using data compression algorithms, which reduce redundancy in the data to be sent, and more efficient modulation. other reasons for the transition is that digital modulation has greater noise immunity than analog, digital signal processing chips have more power and flexibility than analog circuits, and a wide variety of types of information can be transmitted using the same digital modulation. because it is a fixed resource which is in demand by an increasing number of users, the radio spectrum has become increasingly congested in recent decades, and the need to use it more effectively is driving many additional radio innovations such as trunked radio systems, spread spectrum ( ultra - wideband ) transmission, frequency reuse, dynamic spectrum management, frequency pooling, and cognitive radio. = = = itu frequency bands = = = the itu arbitrarily divides the radio spectrum into 12 bands, each beginning at a wavelength which is a power of ten ( 10n ) metres, with corresponding frequency of 3 times a power of ten, and each covering a decade of frequency or wavelength. each of these bands has a traditional name : it can be seen that the bandwidth, the range of frequencies, contained in each band is not equal but increases exponentially as the have to move to track it. in a satellite ground station a microwave transmitter and large satellite dish antenna transmit a microwave uplink beam to the satellite. the uplink signal carries many channels of telecommunications traffic, such as long - distance telephone calls, television programs, and internet signals, using a technique called frequency - division multiplexing ( fdm ). on the satellite, a transponder receives the signal, translates it to a different downlink frequency to avoid interfering with the uplink signal, and retransmits it down to another ground station, which may be widely separated from the first. there the downlink signal is demodulated and the telecommunications traffic it carries is sent to its local destinations through landlines. communication satellites typically have several dozen transponders on different frequencies, which are leased by different users. direct broadcast satellite – a geostationary communication satellite that transmits retail programming directly to receivers in subscriber ' s homes and vehicles on earth, in satellite radio and tv systems. it uses a higher transmitter power than other communication satellites, to allow the signal to be received by consumers with a small unobtrusive antenna. for example, satellite television uses downlink frequencies from 12. 2 to 12. 7 ghz in the ku band transmitted at 100 to 250 watts, which can be received by relatively small 43 – 80 cm ( 17 – 31 in ) satellite dishes mounted on the outside of buildings. = = = other applications = = = = = = = radar = = = = radar is a radiolocation method used to locate and track aircraft, spacecraft, missiles, ships, vehicles, and also to map weather patterns and terrain. a radar set consists of a transmitter and receiver. the transmitter emits a narrow beam of radio waves which is swept around the surrounding space. when the beam strikes a target object, radio waves are reflected back to the receiver. the direction of the beam reveals the object ' s location. since radio waves travel at a constant speed close to the speed of light, by measuring the brief time delay between the outgoing pulse and the received " echo ", the range to the target can be calculated. the targets are often displayed graphically on a map display called a radar screen. doppler radar can measure a moving object ' s velocity, by measuring the change in frequency of the return radio waves due to the doppler effect. radar sets mainly use high frequencies in the microwave bands, because these frequencies create strong reflections from objects the size of vehicles and can be focused into narrow beams with beyond the 11 permitted in the united states for the 2. 4 ghz band, while japan has three more ( 12 – 14 ). 802. 11a / h / j / n / ac / ax can use the 5 ghz u - nii band, which, for much of the world, offers at least 23 non - overlapping 20 mhz channels. this is in contrast to the 2. 4 ghz frequency band where the channels are only 5 mhz wide. in general, lower frequencies have longer range but have less capacity. the 5 ghz bands are absorbed to a greater degree by common building materials than the 2. 4 ghz bands and usually give a shorter range. as 802. 11 specifications evolved to support higher throughput, the protocols have become much more efficient in their bandwidth use. additionally, they have gained the ability to aggregate channels together to gain still more throughput where the bandwidth for additional channels is available. 802. 11n allows for double radio spectrum bandwidth ( 40 mhz ) per channel compared to 802. 11a or 802. 11g ( 20 mhz ). 802. 11n can be set to limit itself to 20 mhz bandwidth to prevent interference in dense communities. in the 5 ghz band, 20 mhz, 40 mhz, 80 mhz, and 160 mhz channels are permitted with some restrictions, giving much faster connections. = = = communication stack = = = wi - fi is part of the ieee 802 protocol family. the data is organized into 802. 11 frames that are very similar to ethernet frames at the data link layer, but with extra address fields. mac addresses are used as network addresses for routing over the lan. wi - fi ' s mac and physical layer ( phy ) specifications are defined by ieee 802. 11 for modulating and receiving one or more carrier waves to transmit the data in the infrared, and 2. 4, 3. 6, 5, 6, or 60 ghz frequency bands. they are created and maintained by the ieee lan / man standards committee ( ieee 802 ). the base version of the standard was released in 1997 and has had many subsequent amendments. the standard and amendments provide the basis for wireless network products using the wi - fi brand. while each amendment is officially revoked when incorporated in the latest version of the standard, the corporate world tends to market to the revisions because they concisely denote capabilities of their products. as a result, in the market place, each revision tends to become its own standard. in addition to 802. 11, the ieee 802 protocol family has specific provisions for wi - fi. changed their sound to a more straightforward rock style. the penultimate track " deep inside " is another of the lighter songs on the album, drawing heavily from funk music. however, it also has a short heavy metal section beginning roughly 3 minutes into the song. the lyrics reference being high on drugs at 3 a. m. in the morning, and as the song goes on the time progresses to 4 a. m. and eventually 5 a. m. " deep inside " stopped being performed live when alex katunich left incubus at the beginning of april 2003, with the last known performance coming during december 2001. the closing track " calgone " lyrically revolves around an alien abduction. it ends with a sound clip of the band arguing with dj lyfe ( who is referred to by his real name of gavin ), for supposedly deleting a track they had been working on in the studio. on physical versions of the album, " calgone " is followed by a hidden track called " segue 1 ", which plays after 30 seconds of silence. the hidden track is also known as " jose loves kate moss, part 1 ", and has been treated as a separate track on streaming sites such as spotify. it begins with a sound recording at a morgue, and the pathologist is describing injuries a patient had sustained during a car crash on may 12, 1997. the hidden track goes on to feature several different sound samples and funk / electronic musical pieces. it samples sounds from the 1985 sorcerer pinball machine and the song " show me your titz ", from hoobastank ' s 1997 demo muffins. it also has an electronic piece in the style of mozart ' s toy symphony, a sound sample of an unknown woman saying " is this the shit, or what? ", and a short skit parodying the karate kid. = = = title and artwork = = = in 1997, einziger claimed that the title reflected the experimental nature of the album, and the creative freedom the band were given. he was quoted as saying, " our album is called s. c. i. e. n. c. e. because we were able to experiment. we were able to take our time and get everything to sound the way we wanted it to — weird science and energetic funk. " it has also been mentioned by various band members that the acronym s. c. i. e. n. c. e. stands for sailing catamarans is every nautical captain the information being sent, and the spectral efficiency of the modulation method used ; how much data it can transmit in each unit of bandwidth. different types of information signals carried by radio have different data rates. for example, a television signal has a greater data rate than an audio signal. the radio spectrum, the total range of radio frequencies that can be used for communication in a given area, is a limited resource. each radio transmission occupies a portion of the total bandwidth available. radio bandwidth is regarded as an economic good which has a monetary cost and is in increasing demand. in some parts of the radio spectrum, the right to use a frequency band or even a single radio channel is bought and sold for millions of dollars. so there is an incentive to employ technology to minimize the bandwidth used by radio services. a slow transition from analog to digital radio transmission technologies began in the late 1990s. part of the reason for this is that digital modulation can often transmit more information ( a greater data rate ) in a given bandwidth than analog modulation, by using data compression algorithms, which reduce redundancy in the data to be sent, and more efficient modulation. other reasons for the transition is that digital modulation has greater noise immunity than analog, digital signal processing chips have more power and flexibility than analog circuits, and a wide variety of types of information can be transmitted using the same digital modulation. because it is a fixed resource which is in demand by an increasing number of users, the radio spectrum has become increasingly congested in recent decades, and the need to use it more effectively is driving many additional radio innovations such as trunked radio systems, spread spectrum ( ultra - wideband ) transmission, frequency reuse, dynamic spectrum management, frequency pooling, and cognitive radio. = = = itu frequency bands = = = the itu arbitrarily divides the radio spectrum into 12 bands, each beginning at a wavelength which is a power of ten ( 10n ) metres, with corresponding frequency of 3 times a power of ten, and each covering a decade of frequency or wavelength. each of these bands has a traditional name : it can be seen that the bandwidth, the range of frequencies, contained in each band is not equal but increases exponentially as the frequency increases ; each band contains ten times the bandwidth of the preceding band. the term " tremendously low frequency " ( tlf ) has been used for wavelengths from 1 – 3 hz ( 300, 000 – 100, 000 km ), though the term has not been defined by the itu. = = regulation = different possibilities of a detection of signals from extra space dimensions at high energy colliders are reviewed. . currently, even blades made of advanced metal alloys used in the engines ' hot section require cooling and careful limiting of operating temperatures. turbine engines made with ceramics could operate more efficiently, giving aircraft greater range and payload for a set amount of fuel. recently, there have been advances in ceramics which include bio - ceramics, such as dental implants and synthetic bones. hydroxyapatite, the natural mineral component of bone, has been made synthetically from a number of biological and chemical sources and can be formed into ceramic materials. orthopedic implants made from these materials bond readily to bone and other tissues in the body without rejection or inflammatory reactions. because of this, they are of great interest for gene delivery and tissue engineering scaffolds. most hydroxyapatite ceramics are very porous and lack mechanical strength and are used to coat metal orthopedic devices to aid in forming a bond to bone or as bone fillers. they are also used as fillers for orthopedic plastic screws to aid in reducing the inflammation and increase absorption of these plastic materials. work is being done to make strong, fully dense nano crystalline hydroxyapatite ceramic materials for orthopedic weight bearing devices, replacing foreign metal and plastic orthopedic materials with a synthetic, but naturally occurring, bone mineral. ultimately these ceramic materials may be used as bone replacements or with the incorporation of protein collagens, synthetic bones. durable actinide - containing ceramic materials have many applications such as in nuclear fuels for burning excess pu and in chemically - inert sources of alpha irradiation for power supply of unmanned space vehicles or to produce electricity for microelectronic devices. both use and disposal of radioactive actinides require their immobilization in a durable host material. nuclear waste long - lived radionuclides such as actinides are immobilized using chemically - durable crystalline materials based on polycrystalline ceramics and large single crystals. alumina ceramics are widely utilized in the chemical industry due to their excellent chemical stability and high resistance to corrosion. it is used as acid - resistant pump impellers and pump bodies, ensuring long - lasting performance in transferring aggressive fluids. they are also used in acid - carrying pipe linings to prevent contamination and maintain fluid purity, which is crucial in industries like pharmaceuticals and food processing. valves made from alumina ceramics demonstrate exceptional durability and resistance to chemical attack, making them reliable for controlling the flow of corrosive liquids. = , and this often works with little to no disruption. to minimize collisions with wi - fi and non - wi - fi devices, wi - fi employs carrier - sense multiple access with collision avoidance ( csma / ca ), where transmitters listen before transmitting and delay transmission of packets if they detect that other devices are active on the channel, or if noise is detected from adjacent channels or non - wi - fi sources. nevertheless, wi - fi networks are still susceptible to the hidden node and exposed node problem. a standard speed wi - fi signal occupies five channels in the 2. 4 ghz band. interference can be caused by overlapping channels. any two channel numbers that differ by five or more, such as 2 and 7, do not overlap ( no adjacent - channel interference ). the oft - repeated adage that channels 1, 6, and 11 are the only non - overlapping channels is, therefore, not accurate. channels 1, 6, and 11 are the only group of three non - overlapping channels in north america. however, whether the overlap is significant depends on physical spacing. channels that are four apart interfere a negligible amount – much less than reusing channels ( which causes co - channel interference ) – if transmitters are at least a few metres apart. in europe and japan where channel 13 is available, using channels 1, 5, 9, and 13 for 802. 11g and 802. 11n is viable and recommended. however, multiple 2. 4 ghz 802. 11b and 802. 11g access - points default to the same channel on initial startup, contributing to congestion on certain channels. wi - fi pollution, or an excessive number of access points in the area, can prevent access and interfere with other devices ' use of other access points as well as with decreased signal - to - noise ratio ( snr ) between access points. these issues can become a problem in high - density areas, such as large apartment complexes or office buildings with multiple wi - fi access points. other devices use the 2. 4 ghz band : microwave ovens, ism band devices, security cameras, zigbee devices, bluetooth devices, video senders, cordless phones, baby monitors, and, in some countries, amateur radio, all of which can cause significant additional interference. it is also an issue when municipalities or other large entities ( such as universities ) seek to provide large area coverage. on some 5 ghz bands interference from radar systems can occur in some places. for base stations that support those bands they employ dynamic frequency selection Question: What contains more calcium than any other organ? A) gall bladder B) lungs C) fingernails D) bones	D) bones
Context: there are a few different mechanisms that can cause white dwarf stars to vary in brightness, providing opportunities to probe the physics, structures, and formation of these compact stellar remnants. the observational characteristics of the three most common types of white dwarf variability are summarized : stellar pulsations, rotation, and ellipsoidal variations from tidal distortion in binary systems. stellar pulsations are emphasized as the most complex type of variability, which also has the greatest potential to reveal the conditions of white dwarf interiors. the united rest mass and charge of a particle correspond to the two forms of the same regularity of the unified nature of its ultimate structure. each of them contains the electric, weak, strong and the gravitational contributions. as a consequence, the force of an attraction among the two neutrinos and force of their repulsion must be defined from the point of view of any of the existing types of the actions. therefore, to understand the nature of the micro world interaction at the fundamental level, one must use the fact that each of the four types of well known forces includes both a kind of the newton and a kind of the coulomb components. the opinion has been spoken that the existence of the gravitational parts of the united rest mass and charge would imply the availability of such a fifth force which come forwards in the system as a unified whole. of the u. k. an unnamed third country is helping as well. according to a report, russia has provided critical help in the project. india ' s main defence - industrial partner is russia, which has carried out considerable research into hypersonic propulsion. the 1 - metric - ton, 5. 6 - meter - long ( 18 ft ) air vehicle under construction features a flattened octagonal cross section with mid - body stub - wings and raked tail fins and a 3. 7 - meter rectangular section air intake. the scramjet engine is located under the mid - body, with the aftbody serving as part of the exhaust nozzle. development work on the engine is also in progress. two parallel fences in the forebody are meant to reduce spillage and increase thrust. part span flaps are provided at the trailing edge of the wings for roll control. a deflectable nozzle cowl at the combustor end can deflect up to 25° to ensure satisfactory performance during power - off and power - on phases. surfaces of the airframe ' s bottom, wings and tail are made of titanium alloy, while aluminum alloy comprises the top surface. the inner surface of the double - wall engine is niobium alloy and the outer surface is nimonic alloy. due to technology denial of material for the scramjet engine, a new program was initiated and the materials were developed in - house. this led to self - sufficiency in the area and the scramjet engine was ground tested successfully for 20s instead of the initial 3s. in the 12 june 2019 test, the cruise vehicle was mounted on an agni - i solid rocket motor to take it to the required altitude. after the required altitude was reached and the mach was achieved, the cruise vehicle was ejected out of the launch vehicle. mid - air the scramjet engine was auto - ignited, and propelled the cruise vehicle at mach 6. drdo spent $ 30 million during design and development phase while $ 4. 5 million was spent on hstdv prototype development. = = testing = = = = = wind tunnel testing = = = a 1 : 16 scale model of the vehicle was tested at a hypersonic wind tunnel operated by israel aerospace industries. the isolated intake has been tested at a trisonic wind tunnel at india ' s national aerospace laboratory ( nal ) in bangalore. during the lab testing the scramjet engine was tested twice for 20s. a total of five to six tests are required before the test flight. the test flight was the military and society field of study. veterans and their issues represent a microcosm of the field. military recruits represent inputs that flow from the community into the armed forces, veterans are outputs that leave the military and reenter society changed by their time as soldiers, sailors, marines and airmen. both society and veteran face multiple layers of adaptation and adjustment upon their reentry. the definition of veteran is surprisingly fluid across countries. in the us, veteran ' s status is established after a service member has completed a minimum period of service. australia requires deployment to a combat zone. in the uk " everyone who has performed military service for at least one day and drawn a day ' s pay is termed a veteran. " the study of veterans focuses much attention on their, sometimes, uneasy transition back to civilian society. " veterans must navigate a complex cultural transition when moving between environments, " and they can expect positive and negative transition outcomes. finding a good job and reestablishing a fulfilling family life is high on their resettlement agenda. military life is often violent and dangerous. the trauma of combat often results in post - traumatic stress disorder as well as painful physical health challenges which often lead to homelessness, suicide, substance, and excessive alcohol use, and family dysfunction. society recognizes its responsibilities to veterans by offering programs and policies designed to redress these problems. veterans also exert an influence on society often through the political process. for example, how do veterans vote and establish party affiliation? during the 2004 presidential election veterans were basically bipartisan. veterans who fought in croatia ' s war of independence voted for the nationalist parties in greater numbers. = = = reserve forces = = = reserve forces are service members who serve the armed forces on a part - time basis. these men and women constitute a " reserve " force that countries rely on for their defense, disaster support, and some day - to - day operations etc. in the united states an active reservist spends a weekend a month and two weeks a year in training. the size of a county ' s reserve force often depends on the type of recruitment method. nations with a volunteer force tend to have a lower reserve percentage. recently the role of the reserves has changed. in many countries it has gone from a strategic force, largely static, to an operational force, largely dynamic. after wwii, relatively large standing forces took care of most operational needs. reserves were held back strategically and deployed in times of emergency for example during the cuban missile crisis. subsequently, the strategic and budget situation changed and ##angulation from bearings taken by two rdf stations separated geographically, as the point where the two bearing lines cross, this is called a " fix ". military forces use rdf to locate enemy forces by their tactical radio transmissions, counterintelligence services use it to locate clandestine transmitters used by espionage agents, and governments use it to locate unlicensed transmitters or interference sources. older rdf receivers used rotatable loop antennas, the antenna is rotated until the radio signal strength is weakest, indicating the transmitter is in one of the antenna ' s two nulls. the nulls are used since they are sharper than the antenna ' s lobes ( maxima ). more modern receivers use phased array antennas which have a much greater angular resolution. animal migration tracking – a widely used technique in wildlife biology, conservation biology, and wildlife management in which small battery - powered radio transmitters are attached to wild animals so their movements can be tracked with a directional rdf receiver. sometimes the transmitter is implanted in the animal. the vhf band is typically used since antennas in this band are fairly compact. the receiver has a directional antenna ( typically a small yagi ) which is rotated until the received signal is strongest ; at this point the antenna is pointing in the direction of the animal. sophisticated systems used in recent years use satellites to track the animal, or geolocation tags with gps receivers which record and transmit a log of the animal ' s location. = = = = remote control = = = = radio remote control is the use of electronic control signals sent by radio waves from a transmitter to control the actions of a device at a remote location. remote control systems may also include telemetry channels in the other direction, used to transmit real - time information on the state of the device back to the control station. uncrewed spacecraft are an example of remote - controlled machines, controlled by commands transmitted by satellite ground stations. most handheld remote controls used to control consumer electronics products like televisions or dvd players actually operate by infrared light rather than radio waves, so are not examples of radio remote control. a security concern with remote control systems is spoofing, in which an unauthorized person transmits an imitation of the control signal to take control of the device. examples of radio remote control : unmanned aerial vehicle ( uav, drone ) – a drone is an aircraft without an onboard pilot, flown by remote control by a pilot in another location, usually in a piloting station on the ground. they are used by the military for reconnaissance and ground attack, and a suitable choice of the four components of the metric tensor which are at our discretion allows to represent geodesically also the non - gravitational motions. emitter rather than returning a diffuse signal detectable at many angles. the effect is sometimes called " glitter " after the very brief signal seen when the reflected beam passes across a detector. it can be difficult for the radar operator to distinguish between a glitter event and a digital glitch in the processing system. stealth airframes sometimes display distinctive serrations on some exposed edges, such as the engine ports. the yf - 23 has such serrations on the exhaust ports. this is another example in the parallel alignment of features, this time on the external airframe. the shaping requirements detracted greatly from the f - 117 ' s aerodynamic properties. it is inherently unstable, and cannot be flown without a fly - by - wire control system. similarly, coating the cockpit canopy with a thin film transparent conductor ( vapor - deposited gold or indium tin oxide ) helps to reduce the aircraft ' s radar profile, because radar waves would normally enter the cockpit, reflect off objects ( the inside of a cockpit has a complex shape, with a pilot helmet alone forming a sizeable return ), and possibly return to the radar, but the conductive coating creates a controlled shape that deflects the incoming radar waves away from the radar. the coating is thin enough that it has no adverse effect on pilot vision. = = = = ships = = = = ships have also adopted similar methods. though the earlier american arleigh burke - class destroyers incorporated some signature - reduction features. the norwegian skjold - class corvettes was the first coastal defence and the french la fayette - class frigates the first ocean - going stealth ships to enter service. other examples are the dutch de zeven provincien - class frigates, the taiwanese tuo chiang - class corvettes, german sachsen - class frigates, the swedish visby - class corvette, the american san antonio - class amphibious transport docks, and most modern warship designs. = = = materials = = = = = = = non - metallic airframe = = = = dielectric composite materials are more transparent to radar, whereas electrically conductive materials such as metals and carbon fibers reflect electromagnetic energy incident on the material ' s surface. composites may also contain ferrites to optimize the dielectric and magnetic properties of a material for its application. = = = = radar - absorbent material = = = = radiation - absorbent material ( ram ), often as paints, are used especially on the edges of metal surfaces. while the material and thickness of ram coatings can consume organic material, breathe oxygen, are able to move, can reproduce sexually, and grow from a hollow sphere of cells, the blastula, during embryonic development. over 1. 5 million living animal species have been described — of which around 1 million are insects — but it has been estimated there are over 7 million animal species in total. they have complex interactions with each other and their environments, forming intricate food webs. = = = viruses = = = viruses are submicroscopic infectious agents that replicate inside the cells of organisms. viruses infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea. more than 6, 000 virus species have been described in detail. viruses are found in almost every ecosystem on earth and are the most numerous type of biological entity. the origins of viruses in the evolutionary history of life are unclear : some may have evolved from plasmids — pieces of dna that can move between cells — while others may have evolved from bacteria. in evolution, viruses are an important means of horizontal gene transfer, which increases genetic diversity in a way analogous to sexual reproduction. because viruses possess some but not all characteristics of life, they have been described as " organisms at the edge of life ", and as self - replicators. = = ecology = = ecology is the study of the distribution and abundance of life, the interaction between organisms and their environment. = = = ecosystems = = = the community of living ( biotic ) organisms in conjunction with the nonliving ( abiotic ) components ( e. g., water, light, radiation, temperature, humidity, atmosphere, acidity, and soil ) of their environment is called an ecosystem. these biotic and abiotic components are linked together through nutrient cycles and energy flows. energy from the sun enters the system through photosynthesis and is incorporated into plant tissue. by feeding on plants and on one another, animals move matter and energy through the system. they also influence the quantity of plant and microbial biomass present. by breaking down dead organic matter, decomposers release carbon back to the atmosphere and facilitate nutrient cycling by converting nutrients stored in dead biomass back to a form that can be readily used by plants and other microbes. = = = populations = = = a population is the group of organisms of the same species that occupies an area and reproduce from generation to generation. population size can be estimated by multiplying population density by the area or volume. the carrying capacity of an environment , 400 km from the persian gulf to the mediterranean sea, but was not paved and was only partially maintained. in around 2, 000 bce, the minoans on the greek island of crete built a 50 km road leading from the palace of gortyn on the south side of the island, through the mountains, to the palace of knossos on the north side of the island. unlike the earlier road, the minoan road was completely paved. ancient minoan private homes had running water. a bathtub virtually identical to modern ones was unearthed at the palace of knossos. several minoan private homes also had toilets, which could be flushed by pouring water down the drain. the ancient romans had many public flush toilets, which emptied into an extensive sewage system. the primary sewer in rome was the cloaca maxima ; construction began on it in the sixth century bce and it is still in use today. the ancient romans also had a complex system of aqueducts, which were used to transport water across long distances. the first roman aqueduct was built in 312 bce. the eleventh and final ancient roman aqueduct was built in 226 ce. put together, the roman aqueducts extended over 450 km, but less than 70 km of this was above ground and supported by arches. = = = pre - modern = = = innovations continued through the middle ages with the introduction of silk production ( in asia and later europe ), the horse collar, and horseshoes. simple machines ( such as the lever, the screw, and the pulley ) were combined into more complicated tools, such as the wheelbarrow, windmills, and clocks. a system of universities developed and spread scientific ideas and practices, including oxford and cambridge. the renaissance era produced many innovations, including the introduction of the movable type printing press to europe, which facilitated the communication of knowledge. technology became increasingly influenced by science, beginning a cycle of mutual advancement. = = = modern = = = starting in the united kingdom in the 18th century, the discovery of steam power set off the industrial revolution, which saw wide - ranging technological discoveries, particularly in the areas of agriculture, manufacturing, mining, metallurgy, and transport, and the widespread application of the factory system. this was followed a century later by the second industrial revolution which led to rapid scientific discovery, standardization, and mass production. new technologies were developed, including sewage systems, electricity, light bulbs, electric motors, railroads, automobiles, and airplanes. these technological advances led to significant developments in medicine , airline baggage tags and are implanted under the skin in pets and livestock ( microchip implant ) and even people. privacy concerns have been addressed with tags that use encrypted signals and authenticate the reader before responding. passive tags use 125 – 134 khz, 13, 900 mhz and 2. 4 and 5 ghz ism bands and have a short range. active tags, powered by a battery, are larger but can transmit a stronger signal, giving them a range of hundreds of meters. submarine communication – when submerged, submarines are cut off from all ordinary radio communication with their military command authorities by the conductive seawater. however radio waves of low enough frequencies, in the vlf ( 30 to 3 khz ) and elf ( below 3 khz ) bands are able to penetrate seawater. navies operate large shore transmitting stations with power output in the megawatt range to transmit encrypted messages to their submarines in the world ' s oceans. due to the small bandwidth, these systems cannot transmit voice, only text messages at a slow data rate. the communication channel is one - way, since the long antennas needed to transmit vlf or elf waves cannot fit on a submarine. vlf transmitters use miles long wire antennas like umbrella antennas. a few nations use elf transmitters operating around 80 hz, which can communicate with submarines at lower depths. these use even larger antennas called ground dipoles, consisting of two ground ( earth ) connections 23 – 60 km ( 14 – 37 miles ) apart, linked by overhead transmission lines to a power plant transmitter. = = = space communication = = = this is radio communication between a spacecraft and an earth - based ground station, or another spacecraft. communication with spacecraft involves the longest transmission distances of any radio links, up to billions of kilometers for interplanetary spacecraft. in order to receive the weak signals from distant spacecraft, satellite ground stations use large parabolic " dish " antennas up to 25 metres ( 82 ft ) in diameter and extremely sensitive receivers. high frequencies in the microwave band are used, since microwaves pass through the ionosphere without refraction, and at microwave frequencies the high - gain antennas needed to focus the radio energy into a narrow beam pointed at the receiver are small and take up a minimum of space in a satellite. portions of the uhf, l, c, s, ku and ka band are allocated for space communication. a radio link that transmits data from the earth ' s surface to a spacecraft is called an uplink, while a link that transmits data from the spacecraft Question: One of the main features all vetebrates have in common is what? A) skeleton B) hard shell C) brain D) backbone	D) backbone
Context: pluripotent cell lines of the embryo, which in turn become fully differentiated cells. a single fertilised egg cell, the zygote, gives rise to the many different plant cell types including parenchyma, xylem vessel elements, phloem sieve tubes, guard cells of the epidermis, etc. as it continues to divide. the process results from the epigenetic activation of some genes and inhibition of others. unlike animals, many plant cells, particularly those of the parenchyma, do not terminally differentiate, remaining totipotent with the ability to give rise to a new individual plant. exceptions include highly lignified cells, the sclerenchyma and xylem which are dead at maturity, and the phloem sieve tubes which lack nuclei. while plants use many of the same epigenetic mechanisms as animals, such as chromatin remodelling, an alternative hypothesis is that plants set their gene expression patterns using positional information from the environment and surrounding cells to determine their developmental fate. epigenetic changes can lead to paramutations, which do not follow the mendelian heritage rules. these epigenetic marks are carried from one generation to the next, with one allele inducing a change on the other. = = plant evolution = = the chloroplasts of plants have a number of biochemical, structural and genetic similarities to cyanobacteria, ( commonly but incorrectly known as " blue - green algae " ) and are thought to be derived from an ancient endosymbiotic relationship between an ancestral eukaryotic cell and a cyanobacterial resident. the algae are a polyphyletic group and are placed in various divisions, some more closely related to plants than others. there are many differences between them in features such as cell wall composition, biochemistry, pigmentation, chloroplast structure and nutrient reserves. the algal division charophyta, sister to the green algal division chlorophyta, is considered to contain the ancestor of true plants. the charophyte class charophyceae and the land plant sub - kingdom embryophyta together form the monophyletic group or clade streptophytina. nonvascular land plants are embryophytes that lack the vascular tissues xylem and phloem. they include mosses, liverworts and hornworts. pteridophytic vascular plants with true xyle and peripheral blood. they concluded from the results that immuno - cytochemical staining of bone marrow and peripheral blood is a sensitive and simple way to detect and quantify breast cancer cells. one of the main reasons for metastatic relapse in patients with solid tumours is the early dissemination of malignant cells. the use of monoclonal antibodies ( mabs ) specific for cytokeratins can identify disseminated individual epithelial tumor cells in the bone marrow. one study reports on having developed an immuno - cytochemical procedure for simultaneous labeling of cytokeratin component no. 18 ( ck18 ) and prostate specific antigen ( psa ). this would help in the further characterization of disseminated individual epithelial tumor cells in patients with prostate cancer. the twelve control aspirates from patients with benign prostatic hyperplasia showed negative staining, which further supports the specificity of ck18 in detecting epithelial tumour cells in bone marrow. in most cases of malignant disease complicated by effusion, neoplastic cells can be easily recognized. however, in some cases, malignant cells are not so easily seen or their presence is too doubtful to call it a positive report. the use of immuno - cytochemical techniques increases diagnostic accuracy in these cases. ghosh, mason and spriggs analysed 53 samples of pleural or peritoneal fluid from 41 patients with malignant disease. conventional cytological examination had not revealed any neoplastic cells. three monoclonal antibodies ( anti - cea, ca 1 and hmfg - 2 ) were used to search for malignant cells. immunocytochemical labelling was performed on unstained smears, which had been stored at - 20 °c up to 18 months. twelve of the forty - one cases in which immuno - cytochemical staining was performed, revealed malignant cells. the result represented an increase in diagnostic accuracy of approximately 20 %. the study concluded that in patients with suspected malignant disease, immuno - cytochemical labeling should be used routinely in the examination of cytologically negative samples and has important implications with respect to patient management. another application of immuno - cytochemical staining is for the detection of two antigens in the same smear. double staining with light chain antibodies and with t and b cell markers can indicate the neoplastic origin of a lymph ##ubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - 20 °c or lower until required. by using culture supernatant or a purified immunoglobulin preparation, further analysis of a potential monoclonal antibody producing hybridoma can be made in terms of reactivity, specificity, and cross - reactivity. = = applications = = the use of monoclonal antibodies is numerous and includes the prevention, diagnosis, and treatment of disease. for example, monoclonal antibodies can distinguish subsets of b cells and t cells, which is helpful in identifying different types of leukaemias. in addition, specific monoclonal antibodies have been used to define cell surface markers on white blood cells and other cell types. this led to the cluster of differentiation series of markers. these are often referred to as cd markers and define several hundred different cell surface components of cells, each specified by binding of a particular monoclonal antibody. such antibodies are extremely useful for fluorescence - activated cell sorting, ##gnant cells. the use of monoclonal antibodies ( mabs ) specific for cytokeratins can identify disseminated individual epithelial tumor cells in the bone marrow. one study reports on having developed an immuno - cytochemical procedure for simultaneous labeling of cytokeratin component no. 18 ( ck18 ) and prostate specific antigen ( psa ). this would help in the further characterization of disseminated individual epithelial tumor cells in patients with prostate cancer. the twelve control aspirates from patients with benign prostatic hyperplasia showed negative staining, which further supports the specificity of ck18 in detecting epithelial tumour cells in bone marrow. in most cases of malignant disease complicated by effusion, neoplastic cells can be easily recognized. however, in some cases, malignant cells are not so easily seen or their presence is too doubtful to call it a positive report. the use of immuno - cytochemical techniques increases diagnostic accuracy in these cases. ghosh, mason and spriggs analysed 53 samples of pleural or peritoneal fluid from 41 patients with malignant disease. conventional cytological examination had not revealed any neoplastic cells. three monoclonal antibodies ( anti - cea, ca 1 and hmfg - 2 ) were used to search for malignant cells. immunocytochemical labelling was performed on unstained smears, which had been stored at - 20 °c up to 18 months. twelve of the forty - one cases in which immuno - cytochemical staining was performed, revealed malignant cells. the result represented an increase in diagnostic accuracy of approximately 20 %. the study concluded that in patients with suspected malignant disease, immuno - cytochemical labeling should be used routinely in the examination of cytologically negative samples and has important implications with respect to patient management. another application of immuno - cytochemical staining is for the detection of two antigens in the same smear. double staining with light chain antibodies and with t and b cell markers can indicate the neoplastic origin of a lymphoma. one study has reported the isolation of a hybridoma cell line ( clone 1e10 ), which produces a monoclonal antibody ( igm, k isotype ). this monoclonal antibody shows specific immuno - cytochemical staining of nucleoli. tissues and tumours can ##ry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - 20 °c or lower until required. by using culture supernatant or a purified immunoglobulin preparation, further analysis of a potential monoclonal antibody producing hybridoma can be made in terms of reactivity, specificity, and cross - reactivity. = = applications = = the use of monoclonal antibodies is numerous and includes the prevention, diagnosis, and treatment of disease. for example, monoclonal antibodies can distinguish subsets of b cells and t cells, which is helpful in identifying different types of leukaemias. in addition, specific monoclonal antibodies have been used to define cell surface markers on white blood cells and other cell types. this led to the cluster of differentiation series of markers. these are often referred to as cd markers and define several hundred different cell surface components of cells, each specified by binding of a particular monoclonal antibody. such antibodies are extremely useful for fluorescence - activated cell sorting, the specific isolation of particular types of cells. = = = in diagnostic histopathology = = = with the help of monoclonal antibodies, tissues and organs can be classified based on their expression of certain defined markers, which reflect tissue or cellular genesis. prostate specific antigen, placental alkaline phospha a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - 20 °c or lower until required. by using culture supernatant or a purified immunoglobulin preparation, further analysis of a potential monoclonal antibody producing hybridoma can be made in terms of reactivity, specificity, and cross - reactivity. = = applications = = the use of mono ##clonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, are changed to larger tissue culture flasks. this maintains the well - being of the hybridomas and provides enough cells for cryopreservation and supernatant for subsequent investigations. the culture supernatant can yield 1 to 60 μg / ml of monoclonal antibody, which is maintained at - 20 °c or lower until required. by using culture supernatant or a purified immunoglobulin preparation, further analysis of a potential monoclonal antibody producing hybridoma can be made in terms of reactivity, specificity, and cross - reactivity. = = applications = = the use of monoclonal antibodies is numerous and includes the prevention, diagnosis, and treatment of disease. for example, monoclonal antibodies can distinguish subsets of b cells and t cells, which is helpful in identifying different types of leukaemias. in addition, specific monoclonal antibodies have been used to define cell surface markers or removed from the dna during programmed stages of development of the plant, and are responsible, for example, for the differences between anthers, petals and normal leaves, despite the fact that they all have the same underlying genetic code. epigenetic changes may be temporary or may remain through successive cell divisions for the remainder of the cell ' s life. some epigenetic changes have been shown to be heritable, while others are reset in the germ cells. epigenetic changes in eukaryotic biology serve to regulate the process of cellular differentiation. during morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo, which in turn become fully differentiated cells. a single fertilised egg cell, the zygote, gives rise to the many different plant cell types including parenchyma, xylem vessel elements, phloem sieve tubes, guard cells of the epidermis, etc. as it continues to divide. the process results from the epigenetic activation of some genes and inhibition of others. unlike animals, many plant cells, particularly those of the parenchyma, do not terminally differentiate, remaining totipotent with the ability to give rise to a new individual plant. exceptions include highly lignified cells, the sclerenchyma and xylem which are dead at maturity, and the phloem sieve tubes which lack nuclei. while plants use many of the same epigenetic mechanisms as animals, such as chromatin remodelling, an alternative hypothesis is that plants set their gene expression patterns using positional information from the environment and surrounding cells to determine their developmental fate. epigenetic changes can lead to paramutations, which do not follow the mendelian heritage rules. these epigenetic marks are carried from one generation to the next, with one allele inducing a change on the other. = = plant evolution = = the chloroplasts of plants have a number of biochemical, structural and genetic similarities to cyanobacteria, ( commonly but incorrectly known as " blue - green algae " ) and are thought to be derived from an ancient endosymbiotic relationship between an ancestral eukaryotic cell and a cyanobacterial resident. the algae are a polyphyletic group and are placed in various divisions, some more closely related to plants than others. there are many differences between them in features such as cell wall composition, biochemistry, ##tase, human chorionic gonadotrophin, α - fetoprotein and others are organ - associated antigens and the production of monoclonal antibodies against these antigens helps in determining the nature of a primary tumor. monoclonal antibodies are especially useful in distinguishing morphologically similar lesions, like pleural and peritoneal mesothelioma, adenocarcinoma, and in the determination of the organ or tissue origin of undifferentiated metastases. selected monoclonal antibodies help in the detection of occult metastases ( cancer of unknown primary origin ) by immuno - cytological analysis of bone marrow, other tissue aspirates, as well as lymph nodes and other tissues and can have increased sensitivity over normal histopathological staining. one study performed a sensitive immuno - histochemical assay on bone marrow aspirates of 20 patients with localized prostate cancer. three monoclonal antibodies ( t16, c26, and ae - 1 ), capable of recognizing membrane and cytoskeletal antigens expressed by epithelial cells to detect tumour cells, were used in the assay. bone marrow aspirates of 22 % of patients with localized prostate cancer ( stage b, 0 / 5 ; stage c, 2 / 4 ), and 36 % patients with metastatic prostate cancer ( stage d1, 0 / 7 patients ; stage d2, 4 / 4 patients ) had antigen - positive cells in their bone marrow. it was concluded that immuno - histochemical staining of bone marrow aspirates are very useful to detect occult bone marrow metastases in patients with apparently localized prostate cancer. although immuno - cytochemistry using tumor - associated monoclonal antibodies has led to an improved ability to detect occult breast cancer cells in bone marrow aspirates and peripheral blood, further development of this method is necessary before it can be used routinely. one major drawback of immuno - cytochemistry is that only tumor - associated and not tumor - specific monoclonal antibodies are used, and as a result, some cross - reaction with normal cells can occur. in order to effectively stage breast cancer and assess the efficacy of purging regimens prior to autologous stem cell infusion, it is important to detect even small quantities of breast cancer cells. immuno - histochemical methods are ideal for this purpose because they are simple, sensitive, and quite specific for nucleotide synthesis. hence, unfused myeloma cells die, as they cannot produce nucleotides by the de novo or salvage pathways because they lack hgprt. removal of the unfused myeloma cells is necessary because they have the potential to outgrow other cells, especially weakly established hybridomas. unfused b cells die as they have a short life span. in this way, only the b cell - myeloma hybrids survive, since the hgprt gene coming from the b cells is functional. these cells produce antibodies ( a property of b cells ) and are immortal ( a property of myeloma cells ). the incubated medium is then diluted into multi - well plates to such an extent that each well contains only one cell. since the antibodies in a well are produced by the same b cell, they will be directed towards the same epitope, and are thus monoclonal antibodies. the next stage is a rapid primary screening process, which identifies and selects only those hybridomas that produce antibodies of appropriate specificity. the first screening technique used is called elisa. the hybridoma culture supernatant, secondary enzyme labeled conjugate, and chromogenic substrate, are then incubated, and the formation of a colored product indicates a positive hybridoma. alternatively, immunocytochemical, western blot, and immunoprecipitation - mass spectrometry. unlike western blot assays, immunoprecipitation - mass spectrometry facilitates screening and ranking of clones which bind to the native ( non - denaturated ) forms of antigen proteins. flow cytometry screening has been used for primary screening of a large number ( ~ 1000 ) of hybridoma clones recognizing the native form of the antigen on the cell surface. in the flow cytometry - based screening, a mixture of antigen - negative cells and antigen - positive cells is used as the antigen to be tested for each hybridoma supernatant sample. the b cell that produces the desired antibodies can be cloned to produce many identical daughter clones. supplemental media containing interleukin - 6 ( such as briclone ) are essential for this step. once a hybridoma colony is established, it will continually grow in culture medium like rpmi - 1640 ( with antibiotics and fetal bovine serum ) and produce antibodies. multiwell plates are used initially to grow the hybridomas, and after selection, Question: Cytoplasmic determinants are distributed how in unfertilized eggs? A) from left to right B) unevenly C) evenly D) symmetrically	B) unevenly
Context: waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mit ##yotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of the earth ' s crust. bacteria also live in symbiotic and parasitic relationships with plants and animals. most bacteria have not been characterised, and only about 27 percent of the bacterial phyla have species that can be grown in the laboratory. archaea constitute the other domain of prokaryotic cells and were initially classified as bacteria, receiving the name archaebacteria ( in the archaebacteria kingdom ), a term that has fallen out of use. archaeal cells have unique properties separating them from the other two domains, bacteria and eukaryota. archaea are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. by which botanists group organisms into categories such as genera or species. biological classification is a form of scientific taxonomy. modern taxonomy is rooted in the work of carl linnaeus, who grouped species according to shared physical characteristics. these groupings have since been revised to align better with the darwinian principle of common descent – grouping organisms by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the by ancestry rather than superficial characteristics. while scientists do not always agree on how to classify organisms, molecular phylogenetics, which uses dna sequences as data, has driven many recent revisions along evolutionary lines and is likely to continue to do so. the dominant classification system is called linnaean taxonomy. it includes ranks and binomial nomenclature. the nomenclature of botanical organisms is codified in the international code of nomenclature for algae, fungi, and plants ( icn ) and administered by the international botanical congress. kingdom plantae belongs to domain eukaryota and is broken down recursively until each species is separately classified. the order is : kingdom ; phylum ( or division ) ; class ; order ; family ; genus ( plural genera ) ; species. the scientific name of a plant represents its genus and its species within the genus, resulting in a single worldwide name for each organism. for example, the tiger lily is lilium columbianum. lilium is the genus, and columbianum the specific epithet. the combination is the name of the species. when writing the scientific name of an organism, it is proper to capitalise the first letter in the genus and put all of the specific epithet in lowercase. additionally, the entire term is ordinarily italicised ( or underlined when italics are not available ). the evolutionary relationships and heredity of a group of organisms is called its phylogeny. phylogenetic studies attempt to discover phylogenies. the basic approach is to use similarities based on shared inheritance to determine relationships. as an example, species of pereskia are trees or bushes with prominent leaves. they do not obviously resemble a typical leafless cactus such as an echinocactus. however, both pereskia and echinocactus have spines produced from areoles ( highly specialised pad - like structures ) suggesting that the two genera are indeed related. judging relationships based on shared characters requires care, since plants may resemble one another through convergent evolution in which characters have arisen independently. some euphorbias have leafless, rounded bodies adapted to water conservation similar to those of globular cacti, but characters such as the structure of their flowers make it clear that the two groups are not closely related. the cladistic method takes a systematic approach to characters, distinguishing between those that carry no information about shared evolutionary history – such as those evolved separately in different groups ( homoplasies ) or those left over from ancestors ( plesiomorphies ) – and derived characters, which are further divided into multiple recognized phyla. archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of haloquadratum walsbyi. despite this morphological similarity to bacteria, archaea possess genes and several metabolic pathways that are more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mitochondria and chloroplasts, both of which are now part of modern - day eukaryotic cells. the major lineages of eukaryotes diversified in the precambrian about 1. 5 billion years ago and can be classified into eight major clades : alveolates, organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mitochondria and chloroplasts, both of which are now part of modern - day eukaryotic cells. the major lineages of eukaryotes diversified in the precambrian about 1. 5 billion years ago and can be classified into eight major clades : alveolates, excavates, stramenopiles, plants, rhizarians, amoebozoans, fungi, and animals. five of these clades are collectively known as protists, which are mostly microscopic eukaryotic organisms that are not plants, fungi, or animals. while it is likely that protists share a common ancestor ( the last eukaryotic common ancestor ), protists by themselves do not constitute a separate clade as some protists may be more closely related to plants, fungi, or animals than they are to other protists. like groupings such as algae, , tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off the non - avian dinosaurs, mammals increased rapidly in size and diversity. such mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. = = diversity = = = = = bacteria and archaea = = = bacteria are a type of cell that constitute a large domain of prokaryotic microorganisms. typically a few micrometers in length, bacteria have a number of shapes, ranging from spheres to rods and spirals. bacteria were among the first life forms to appear on earth, and are present in most of its habitats. bacteria inhabit soil, water, acidic hot springs, radioactive into major divisions, starting with four eons ( hadean, archean, proterozoic, and phanerozoic ), the first three of which are collectively known as the precambrian, which lasted approximately 4 billion years. each eon can be divided into eras, with the phanerozoic eon that began 539 million years ago being subdivided into paleozoic, mesozoic, and cenozoic eras. these three eras together comprise eleven periods ( cambrian, ordovician, silurian, devonian, carboniferous, permian, triassic, jurassic, cretaceous, tertiary, and quaternary ). the similarities among all known present - day species indicate that they have diverged through the process of evolution from their common ancestor. biologists regard the ubiquity of the genetic code as evidence of universal common descent for all bacteria, archaea, and eukaryotes. microbial mats of coexisting bacteria and archaea were the dominant form of life in the early archean eon and many of the major steps in early evolution are thought to have taken place in this environment. the earliest evidence of eukaryotes dates from 1. 85 billion years ago, and while they may have been present earlier, their diversification accelerated when they started using oxygen in their metabolism. later, around 1. 7 billion years ago, multicellular organisms began to appear, with differentiated cells performing specialised functions. algae - like multicellular land plants are dated back to about 1 billion years ago, although evidence suggests that microorganisms formed the earliest terrestrial ecosystems, at least 2. 7 billion years ago. microorganisms are thought to have paved the way for the inception of land plants in the ordovician period. land plants were so successful that they are thought to have contributed to the late devonian extinction event. ediacara biota appear during the ediacaran period, while vertebrates, along with most other modern phyla originated about 525 million years ago during the cambrian explosion. during the permian period, synapsids, including the ancestors of mammals, dominated the land, but most of this group became extinct in the permian – triassic extinction event 252 million years ago. during the recovery from this catastrophe, archosaurs became the most abundant land vertebrates ; one archosaur group, the dinosaurs, dominated the jurassic and cretaceous periods. after the cretaceous – paleogene extinction event 66 million years ago killed off more closely related to those of eukaryotes, notably for the enzymes involved in transcription and translation. other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. archaea use more energy sources than eukaryotes : these range from organic compounds, such as sugars, to ammonia, metal ions or even hydrogen gas. salt - tolerant archaea ( the haloarchaea ) use sunlight as an energy source, and other species of archaea fix carbon, but unlike plants and cyanobacteria, no known species of archaea does both. archaea reproduce asexually by binary fission, fragmentation, or budding ; unlike bacteria, no known species of archaea form endospores. the first observed archaea were extremophiles, living in extreme environments, such as hot springs and salt lakes with no other organisms. improved molecular detection tools led to the discovery of archaea in almost every habitat, including soil, oceans, and marshlands. archaea are particularly numerous in the oceans, and the archaea in plankton may be one of the most abundant groups of organisms on the planet. archaea are a major part of earth ' s life. they are part of the microbiota of all organisms. in the human microbiome, they are important in the gut, mouth, and on the skin. their morphological, metabolic, and geographical diversity permits them to play multiple ecological roles : carbon fixation ; nitrogen cycling ; organic compound turnover ; and maintaining microbial symbiotic and syntrophic communities, for example. = = = eukaryotes = = = eukaryotes are hypothesized to have split from archaea, which was followed by their endosymbioses with bacteria ( or symbiogenesis ) that gave rise to mitochondria and chloroplasts, both of which are now part of modern - day eukaryotic cells. the major lineages of eukaryotes diversified in the precambrian about 1. 5 billion years ago and can be classified into eight major clades : alveolates, excavates, stramenopiles, plants, rhizarians, amoebozoans, fungi, and animals. five of these clades are collectively known as protists, which are mostly microscopic eukaryotic organisms that are not plants, fungi, or animals. while it is Question: What relatively new addition to and highest level of the system of taxonomic classification includes just three divisions, the eukarya, the archaea, and the bacteria? A) element B) content C) branch D) domain	D) domain

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