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The first designer babies will not be overly designed. | [
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It's most likely that they will be created to eliminate a deadly genetic disease running in a family. | [
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As the technology progresses and gets more refined, more and more people may argue that not using genetic modification is unethical | [
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because it condemns children to preventable suffering and death and denies them the cure. | [
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But as soon as the first engineered kid is born, a door is opened that can't be closed anymore. | [
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Early on, vanity traits will mostly be left alone. | [
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But as genetic modification becomes more accepted and our knowledge of our genetic code enhances, the temptation will grow. | [
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Huge changes are made as a result of the personal decisions of millions of individuals that accumulate. | [
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This is a slippery slope. | [
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Modified humans could become the new standard. | [
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But as engineering becomes more normal and our knowledge improves, we could solve the single biggest mortality risk factor, aging. | [
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Two-thirds of the 150,000 people who die today will die of age-related causes. | [
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Currently, we think aging is caused by the accumulation of damage to our cells, like DNA breaks and the systems responsible for fixing those wearing off over time. | [
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But there are also genes that directly affect aging. | [
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A combination of genetic engineering and other therapy could stop or slow down aging, maybe even reverse it. | [
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We know from nature that there are animals immune to aging. | [
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Maybe we could even borrow a few genes for ourselves. | [
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Some scientists even think biological aging could be something that eventually just stops being a thing. | [
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We would still die at some point, but instead of doing so in hospitals at age 90, we might be able to spend a few thousand years with our loved ones. | [
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Research into this is in its infancy. | [
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But it is conceivable that people alive today might be the first to profit from effective anti-aging therapy. | [
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All we might need is for someone to convince a smart billionaire to make it their next problem to solve. | [
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On a bigger scale, we certainly could solve many problems by having a modified population. | [
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In possession of a modified immune system with a library of potential threats, we might become immune to most diseases that haunt us today. | [
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Many of you watching will feel uncomfortable and fear that we will create a world in which we will reject non-perfect humans and pre-select features and qualities based on our idea of what's healthy. | [
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Tests for dozens of genetic diseases or complications have become standard for pregnant women in much of the world. | [
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The decision to terminate a pregnancy is incredibly personal, but it's important to acknowledge the reality that we are pre-selecting humans based on medical conditions. | [
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There is also no use in pretending this will change, so we have to act carefully and respectfully as we advance the technology and can make more and more selections. | [
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The gene edit might achieve the desired result, disabling a disease, but also might accidentally trigger unwanted changes. | [
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We just don't know enough yet about the complex interplay of our genes to avoid unpredictable consequences. | [
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Working on accuracy and monitoring methods is a major concern as the first human trials begin. | [
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And since we've discussed a possible positive future, there are darker visions too. | [
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Could a state cement its rule forever by forcing gene editing on their subjects? | [
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What would stop a totalitarian regime from engineering an army of modified super soldiers? | [
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Scenarios like this one are far, far off into the future, if they ever become possible at all. | [
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The basic proof of concept for genetic engineering like this already exists today. | [
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The technology really is that powerful. | [
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While this might be a tempting reason to ban genetic editing and related research, that would certainly be a mistake. | [
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Only by participating can we make sure that further research is guided by caution, reason, oversight and transparency. | [
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Most of us have something wrong with them. | [
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In the future that lies ahead of us, would we have been allowed to exist? | [
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The technology is certainly a bit scary, but we have a lot to gain and genetic engineering might just be a step in the natural evolution of intelligent species in the universe. | [
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We could extend our life expectancy by centuries and travel to the stars. | [
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In its salivary glands, thousands of sporozoites wait until the insect penetrates your skin. | [
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Immediately after invading you, they head for the liver, where they quietly enter big cells and hide from the immune system. | [
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For up to a month, they stay here in stealth mode, consuming the cells alive and changing into their next form, small, drop-like mirrozoites. | [
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There are trillions of them, and a single one can lay up to 300 eggs at a time. | [
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For the first time in human history, we have the tools to make fast, large-scale changes to entire species, changing their genetic information as we please. | [
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Using genetic engineering, scientists successfully created a strain of mosquitoes that are immune to the malaria parasite by adding a new antibody gene that specifically targets plasmodium. | [
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